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GBIF data worden gebruikt in wetenschappelijke publicaties. Deze pagina verschaft een overzicht, via de literatuur verzamel site Mendeley, van publicaties die GBIF noemen of die gebaseerd zijn op GBIF data.. ...

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Recombinant Human coronavirus SARS Nucleoprotein is an Escherichia coli Protein fragment 1 to 49 aa range, | 95% purity and validated in WB, ELISA, SDS-PAGE.

Poppe, M.; Wittig, S.; Jurida, L.; Bartkuhn, M.; Wilhelm, J.; Müller, H.; Beuerlein, K.; Karl, N.; Bhuju, S.; Ziebuhr, J.; Schmitz, M.Lienhard.; Kracht, M., 2017: The NF-κB-dependent and -independent transcriptome and chromatin landscapes of human coronavirus 229E-infected cells

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Human coronavirus. Coloured transmission electron micrograph (TEM) of Human coronavirus particles (purple circles). Coronaviruses primarily infect the upper respiratory and gastrointestinal tract and can cause the common cold, gastrointestinal infections and SARS (severe acute respiratory syndrome). Coronaviruses are named after the corona (crown) of surface proteins (dark dots) that are used to penetrate a host cell. Once inside the cell, the virus particles (virions) use the cells machinery to make more copies of themselves. Magnification: x67,000 when printed 10 centimetres tall. - Stock Image C001/0467

The four endemic human coronaviruses HCoV-229E, -NL63, -OC43, and -HKU1 contribute a considerable share of upper and lower respiratory tract infections in adults and children. While their clinical representation resembles that of many other agents of the common cold, their evolutionary histories, an …

Human coronaviruses can sometimes cause lower-respiratory tract illnesses, such as pneumonia or bronchitis. This is more common in people with cardiopulmonary disease, people with weakened immune systems, infants, and older adults.. Other human coronaviruses. Two other human coronaviruses, MERS-CoV and SARS-CoV have been known to frequently cause severe symptoms. MERS symptoms usually include fever, cough, and shortness of breath which often progress to pneumonia. About 3 or 4 out of every 10 patients reported with MERS have died. MERS cases continue to occur, primarily in the Arabian Peninsula. SARS symptoms often included fever, chills, and body aches which usually progressed to pneumonia. No human cases of SARS have been reported anywhere in the world since 2004.. Transmission. Human coronaviruses most commonly spread from an infected person to others through the air by coughing and sneezing close personal contact, such as touching or shaking hands touching an object or surface with the virus ...

Human coronaviruses (HCV) cause various respiratory, gastrointestinal and possibly neurological disorders. Very little is known of the molecular biology of these ubiquitous pathogens. We have...

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Coronaviruses were classified as a distinct group of viruses in 19681 and are now recognized as the etiologic agents of an increasing number of diseases of man and animals2-7. At least four members...

Pandemics, even more than other medical problems, require swift integration of knowledge. When caused by a new virus, understanding the underlying biology may help finding solutions. In a setting where there are a large number of loosely related projects and initiatives, we need common ground, also known as a

Nucleic Acid: Human Coronavirus 229E plasmid for in vitro transcription. (Diagnostic reagent, Derived product, Nucleic Acid, Cloned nucleic acid)

John Yin is working to find out whether junk particles produced by mouse viruses exist in human coronaviruses, and whether they may be the key to understanding how the viruses spread and interact with host cells.. ...

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1. PerlmanS, NetlandJ (2009) Coronaviruses post-SARS: update on replication and pathogenesis. Nat Rev Microbiol 7: 439-450.. 2. RotaPA, ObersteMS, MonroeSS, NixWA, CampganoliR, et al. (2003) Characterization of a novel coronavirus associated with severe acute respiratory syndrome. Science 300: 1394-1399.. 3. DrostenC, GuntherS, PreiserW, van der WerfS, BrodtHR, et al. (2003) Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N Engl J Med 348: 1967-1976.. 4. PyrcK, BerkhoutB, van der HoekL (2007) The novel human coronaviruses NL63 and HKU1. J Virol 81: 3051-3057.. 5. ZakiAM, van BoheemenS, BestebroerTM, OsterhausAD, FouchierRA (2012) Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N Engl J Med 367: 1814-1820.. 6. DanielssonN, CatchpoleM (2012) Novel coronavirus associated with severe respiratory disease: case definition and public health measures. Euro Surveill 17: 20282.. 7. AssiriA, McGeerA, PerlTM, PriceCS, Al RabeeahAA, et al. ...

Human coronaviruses are common throughout the world and were first identified in the mid-1960s. Seven different coronaviruses, that scientists know of, can infect people and make them sick.. Common human coronaviruses, including types 229E, NL63, OC43, and HKU1, usually cause mild to moderate upper-respiratory tract illnesses, like the common cold. Most people get infected with these viruses at some point in their lives. These illnesses usually only last for a short amount of time. Human coronaviruses can sometimes cause lower-respiratory tract illnesses, such as pneumonia or bronchitis. This is more common in people with cardiopulmonary disease, people with weakened immune systems, infants, and older adults.. Two other human coronaviruses, MERS-CoV and SARS-CoV, have been known to frequently cause severe symptoms. MERS symptoms usually include fever, cough, and shortness of breath which often progress to pneumonia. About 3 or 4 out of every 10 patients reported with MERS have died. MERS cases ...

TY - JOUR. T1 - Oligomerization of the carboxyl terminal domain of the human coronavirus 229E nucleocapsid protein. AU - Lo, Yu Sheng. AU - Lin, Shing Yen. AU - Wang, Shiu Mei. AU - Wang, Chin Tien. AU - Chiu, Ya Li. AU - Huang, Tai Huang. AU - Hou, Ming Hon. N1 - Funding Information: This work was supported by the NSC Grant 100-2113-M-005-004-MY3 to M.-H.H. We thank Dr. Hui-Chi Hung (Chung-Hsing University) for her help on AUC experiments. PY - 2013/1/16. Y1 - 2013/1/16. N2 - The coronavirus (CoV) N protein oligomerizes via its carboxyl terminus. However, the oligomerization mechanism of the C-terminal domains (CTD) of CoV N proteins remains unclear. Based on the protein disorder prediction system, a comprehensive series of HCoV-229E N protein mutants with truncated CTD was generated and systematically investigated by biophysical and biochemical analyses to clarify the role of the C-terminal tail of the HCoV-229E N protein in oligomerization. These results indicate that the last C-terminal tail ...

http://philosophers-stone.info/wp-content/uploads/2020/11/The-scam-has-been-confirmed-Dsalud-November-2020.pdf). Have any human coronaviruses been isolated?. the alleged isolation work of suspected human coronaviruses 229E (said to have been isolated in 1965), OC43 (in 1967), SARS-CoV (in 2003), NL63 (in 2004), HKU1 (in 2005) and MERSCoV (in 2012).. In essence, NOT ONE OF THE SEVEN SUPPOSED HUMAN CORONAVIRUS HAS REALLY BEEN ISOLATED. The only thing that has been different between them are the laboratory procedures and techniques that were becoming progressively more sophisticated which, in this case, has implied not a greater accuracy but a greater capacity for deception and self-deception that has culminated in the virtual manufacture of the SARS-CoV-2.. And the obvious consequence of the lack of evidence of its isolation is that such coronaviruses cannot be held responsible for any disease. Moreover, all tests - of whatever kind - based on the presumed components of these viruses ...

Home and office disinfectant. As a disinfectant, KAYQUAT II kills over 20 different bacteria/virus. Our disinfectant spray meets EPAs criteria for use against Human Coronavirus. For spray applications, cover or remove all food products. For Human Coronavirus treated surfaces must remain wet for 1 minute.

Since the first cases of coronavirus were reported in December 2019 in Wuhan, China, the scientific community has been searching for an effective treatment, relying largely on prior knowledge about the other 6 known human coronaviruses to date, of which, the SARS-CoV and the MERS-CoV were responsible for major epidemics in 2003 and 2012 respectively.. It was precisely in 2003 when Savarino et al. hypothesized the possible usefulness of chloroquine and hydroxychloroquine in the treatment of SARS-CoV,1 prompting several studies in subsequent years trying to evaluate its in vitro antiviral efficacy against this and other human coronaviruses, collected in a review recently published by Raoult et al.2. The different investigations carried out since then attribute to these 2 drugs an antiviral action dependent on multiple mechanisms, sometimes replicated in in vivo studies, and that, in the case of COVID-19, could include interference with glycosylation of the ACE2 receptor that the virus uses to bind ...

In deze video, tonen we een alternatieve methode voor de detectie en titering van virussen met behulp van een enzymatische antigeen...

Before the SARS outbreak only two human coronaviruses (HCoV) were known: HCoV-OC43 and HCoV-229E. With the discovery of SARS-CoV in 2003, a third family member ...

The ongoing outbreak of the novel human coronavirus SARS-CoV-2 (also known as 2019-nCoV) has become a global health concern. Rapid and ease-to-use diagnostic techniques are urgently needed to diagnose SARS-CoV-2 infection.We devised a reverse transcription multiple cross displacement amplification (RT-MCDA) coupled with nanoparticles-based biosensor (BS) assay (RT-MCDA-BS) for rapid, sensitive and specific diagnosis of COVID-19. Two primer sets were designed to target the open reading frame 1a/b (F1ab) and nucleoprotein gene (N) of SARS-CoV-2. A total of 183 clinical samples, including 65 patients with COVID-19 infections and 118 patients with other pathogen infections, were used to testify the assays feasibility. The diagnosis results were visually reported using BS.The designed assay was performed using a simple instrument which could maintain the reaction in a constant temperature at 64°C for only 35 min. The total procedure of COVID-19 RT-MCDA-BS test could be finished within 1 h. The ...

4IUM: Deubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cells.

There are many types of human coronaviruses including some that commonly cause mild upper-respiratory tract illnesses. COVID-19 is a new disease, caused by a novel (or new) coronavirus that has not previously been seen in humans. ...

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