TY - JOUR. T1 - Explaining the decline in coronary heart disease mortality rates in Japan. T2 - Contributions of changes in risk factors and evidence-based treatments between 1980 and 2012. AU - Ogata, Soshiro. AU - Nishimura, Kunihiro. AU - Guzman-Castillo, Maria. AU - Sumita, Yoko. AU - Nakai, Michikazu. AU - Nakao, Yoko M.. AU - Nishi, Nobuo. AU - Noguchi, Teruo. AU - Sekikawa, Akira. AU - Saito, Yoshihiko. AU - Watanabe, Taeko. AU - Kobayashi, Yasuki. AU - Okamura, Tomonori. AU - Ogawa, Hisao. AU - Yasuda, Satoshi. AU - Miyamoto, Yoshihiro. AU - Capewell, Simon. AU - OFlaherty, Martin. PY - 2019/9/15. Y1 - 2019/9/15. N2 - Background: We aimed to quantify contributions of changes in risks and uptake of evidence-based treatment to coronary heart disease (CHD) mortality trends in Japan between 1980 and 2012. Methods: We conducted a modelling study for the general population of Japan aged 35 to 84 years using the validated IMPACT model incorporating data sources like Vital Statistics. The main ...
Stressful Life Events and Coronary Heart Disease Patients, 978-613-8-23434-0, Psychological factors play a very important role in the existence and formation of Heart diseases, especially Coronary Heart Disease (CHD). Nowadays, heart diseases especially CHD which its clinical spectrum varies from silence ischemia to stable angina, unstable angina, myocardial infection and sudden heart death is one of the three main causes of death in the industrial countries besides cancer and brain stroke. Fifty million people die annually around the world; 12 million of them die because of cardiovascular diseases.Stress can affect persons health through behavioral and physiologic changes. Stress can also lead to heart diseases through psychological changes. It seems that stress has direct effects on coronary arteries and heart muscles. Nontraditional risk factors, such as psychological traits, have been increasingly recognized as important contributors to the genesis and outcomes of coronary artery disease. Mental
The Stanford Five-City Project was initiated in 1978 to evaluate the effects of community-wide health education on coronary heart disease risk factors in two control San Luis Obispo and Modesto and two treatment Monterey and Salinas cities. This paper examines sex differences in the prevalence of smoking, hypercholesterolemia, and hypertension...
This multicenter, randomized, double-blind, placebo-controlled, parallel-group study will evaluate the potential of dalcetrapib to reduce cardiovascular morbidity and mortality in patients with stable coronary heart disease (CHD), with CHD risk equivalents or at elevated risk for cardiovascular disease. Eligible patients will be randomized to receive either dalcetrapib 600 mg orally daily or placebo orally daily, on a background of contemporary, guidelines-based medical care. Anticipated time on study treatment is 4 years ...
This multicenter, randomized, double-blind, placebo-controlled, parallel-group study will evaluate the potential of dalcetrapib to reduce cardiovascular morbidity and mortality in patients with stable coronary heart disease (CHD), with CHD risk equivalents or at elevated risk for cardiovascular disease. Eligible patients will be randomized to receive either dalcetrapib 600 mg orally daily or placebo orally daily, on a background of contemporary, guidelines-based medical care. Anticipated time on study treatment is 4 years ...
heartdiseasehotline - informative website on coronary heart disease, congential heart disease, heart disease women, rheumatic heart disease, heart disease prevention, heart disease risk (archive ID #3) - Read it at RSS2.com
heartdiseasehotline - informative website on coronary heart disease, congential heart disease, heart disease women, rheumatic heart disease, heart disease prevention, heart disease risk - Read it at RSS2.com
Coronary heart disease currently affects more than 7 million Americans, making it the most common form of heart disease. Men initially have a greater risk for developing coronary heart disease than women do. Once a woman reaches menopause however, her risk for heart disease eventually equals or surpasses that of a man. Experts believe this may be due in part to a decrease in the production of estrogen, a female sex hormone that appears to offer some protection against heart disease.. Coronary heart disease remains the number one cause of death for both women and men in the US, accounting for more than 500,000 deaths from heart attacks each year. Experts agree that many of these deaths can be prevented by changes in lifestyle, which when implemented, can directly reduce your chances for developing coronary heart disease.. Risk factors for coronary heart disease are circumstances or conditions that increase the likelihood of your developing this disease. Risk factors are generally divided into two ...
Heart disease is the number one killer in the United States (American Heart Association, 2005). The purpose of this study was to demonstrate the results of a twelve-week exercise program on coronary heart disease risk factors in full-time hospital employees. Methods: The participants were given cardiovascular, weight training, and flexibility recommendations to follow during a twelve-week period. The main heart disease risk factors measured before and after the completion of the exercise program were blood pressure, total cholesterol, HDL-cholesterol, and body mass index. The information was put into the Framingham Heart Score to estimate the participants 10-year risk of developing heart disease. Other factors measured to show the benefits of exercise included resting heart rate, weight, body fat percentage, waist and hip ratio, maximal oxygen uptake (VO2), and flexibility. Results: There were no significant results from any measurements taken.
BACKGROUND Adult height has been inversely associated with coronary heart disease risk in several studies. The mechanism for this association is not well understood, however, and this was investigated by examining components of stature, cardiovascular disease risk factors and subsequent coronary heart disease in a prospective study. METHODS All men aged 45-59 years living in the town of Caerphilly, South Wales were approached, and 2512 (89%) responded and underwent a detailed examination, which included measurement of height and sitting height (from which an estimate of leg length was derived). Participants were followed up through repeat examinations and the cumulative incidence of coronary heart disease-both fatal and non-fatal-over a 15 year follow up period is the end point in this report. RESULTS Cross sectional associations between cardiovascular risk factors and components of stature (total height, leg length and trunk length) demonstrated that factors related to the insulin resistance ...
Results:. Study 1: 10-year cardiovascular mortality was significantly and linearly associated with glycemic control (fasting blood glucose and glycated hemoglobin A1 levels) independently of the mode of treatment. A high fasting blood glucose level significantly predicted cardiovascular mortality in multiple logistic regression analysis independently of other risk factors. Study 2: Glycated hemoglobin A1c was the most important single risk factor associated with coronary heart disease death or all coronary heart disease events. In multiple logistic regression analysis, glycated hemoglobin A1c was significantly associated with coronary heart disease death after adjustment for other cardiovascular risk factors. ...
Higher magnesium intake was linked to a statistically significant risk reduction in fatal coronary heart disease and a risk reduction for sudden cardiac death among postmenopausal women, according to an analysis published in the Journal of Women’s Health.“Our understanding of the etiology and risk factors for fatal coronary heart disease and sudden cardiac death, particularly among
TY - JOUR. T1 - Ten-year predicted coronary heart disease risk in HIV-infected men and women. AU - Kaplan, Robert C.. AU - Kingsley, Lawrence A.. AU - Sharrett, A. Richey. AU - Li, Xiuhong. AU - Lazar, Jason. AU - Tien, Phyllis C.. AU - Mack, Wendy J.. AU - Cohen, Mardge H.. AU - Jacobson, Lisa. AU - Gange, Stephen J.. PY - 2007/10/22. Y1 - 2007/10/22. N2 - Background. Highly active antiretroviral therapy (HAART), in addition to traditional vascular risk factors, may affect coronary heart disease (CHD) risk in individuals with human immunodeficiency virus (HIV) infection. Methods. Among HIV-infected (931 men and 1455 women) and HIV-uninfected (1099 men and 576 women) adults, the predicted risk of CHD was estimated on the basis of age, sex, lipid and blood pressure levels, the presence of diabetes, and smoking status. Results. Among HIV-infected men, 2% had moderate predicted risk of CHD (10-year CHD risk, 15%-25%), and 17% had high predicted risk (10-year CHD risk of ≥25% or diabetes). Among ...
Results. Both middle-aged and elderly men with T wave amplitudes ≥0.15 mV had a lower risk of myocardial infarction, coronary heart disease death and sudden death than men with T wave amplitudes 0.05 to 0.15 mV. The adjusted relative risk of coronary heart disease death was 0.5 (95% confidence interval [CI] 0.2 to 1.0); in men with T wave amplitude ≤0.05 mV, relative risk was 2.0 (95% CI 1.3 to 3.1). Slight ST segment elevation was also associated with decreased risk: relative risk 0.5 (95% CI 0.3 to 1.0) compared with the isoelectric ST segment level. In men with ST segment depression, relative risk was 2.2 (95% CI 1.4 to 3.4). The associations of T wave amplitude and ST segment level were independent of each other. ...
I dont know what to make of this new study. http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001177 Background...
I dont like Mondays"---day of the week of coronary heart disease deaths in Scotland: study of routinely collected data Academic Article ...
In a prospective study of over 17 000 civil servants followed up for 25 years, there was an inverse association between SES and CHD mortality in participants with and without prevalent CHD at baseline.. The inverse social gradient in CHD mortality could be a result of increased incidence (aetiology), case fatality (prognosis) or both among those of lower SES. Case fatality includes both survival of an acute event, such as myocardial infarction, and prognosis in chronic manifestations of CHD, such as angina. We studied the latter-established CHD in a working population- and found a significant effect of SES on CHD mortality among those with prevalent CHD defined by symptomatic status. When prevalent CHD was defined by Q, ST or T abnormality in the absence of symptoms, the SES effect was similar but the confidence intervals spanned unity. Participants with both symptoms and ECG abnormality were at very high risk (relative to those without symptoms or any ECG abnormality) and in this group there ...
Doug Manuel, MD, MSc, William M. Flanagan, BM, Meltem Tuna, PhD, Anya Okhmatovskaia, PhD, Philippe Finès, PhD; Carol Bennett, MSc. Coronary heart disease risk factors in Canada: a Microsimulation predictive model. Simulated Technology for Applied Research (STAR). Slideshow 3725048 by cicero
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TY - JOUR. T1 - Consensus on. T2 - Screening and therapy of coronary heart disease in diabetic patients. AU - Rivellese, A. A.. AU - Piatti, P. M.. PY - 2011/10. Y1 - 2011/10. N2 - The screening and best treatment for coronary heart disease in diabetic patients is still a matter of debate. For this reason the main Italian scientific societies dealing with diabetes and cardiovascular diseases have tried to finalize a document providing shared recommendations based on the available evidence on: 1) how and who to screen for coronary heart disease, 2) methodologies for the characterization of existing coronary heart disease 3) evaluation of the optimal treatment of cardiovascular risk factors and 4) appropriate revascularization procedures. For each of these points, the levels of evidence and strength of recommendations used in the Italian Standard of Care were adopted.. AB - The screening and best treatment for coronary heart disease in diabetic patients is still a matter of debate. For this reason ...
TY - JOUR. T1 - Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke. T2 - A pooled analysis of 97 prospective cohorts with 1·8 million participants. AU - The Global Burden of Metabolic Risk Factors for Chronic Diseases Collaboration (BMI Mediated Effects). AU - Lu, Yuan. AU - Hajifathalian, Kaveh. AU - Ezzati, Majid. AU - Woodward, Mark. AU - Rimm, Eric B.. AU - Danaei, Goodarz. AU - Selmer, Randi. AU - Strand, Bjorn H.. AU - Dobson, A.. AU - Hozawa, A.. AU - Nozaki, A.. AU - Okayama, Akira. AU - Rodgers, A.. AU - Tamakoshi, A.. AU - Zhou, B. F.. AU - Zhou, B.. AU - Yao, C. H.. AU - Jiang, C. Q.. AU - Gu, D. F.. AU - Heng, D.. AU - Giles, Graham G.. AU - Shan, G. L.. AU - Whitlock, G.. AU - Arima, H.. AU - Kim, H. C.. AU - Christensen, H.. AU - Horibe, H.. AU - Maegawa, H.. AU - Tanaka, H.. AU - Ueshima, Hirotsugu. AU - Zhang, H. Y.. AU - Kim, I. S.. AU - Suh, I.. AU - Fuh, J. L.. AU - Lee, J.. AU - Woo, Jean. AU - Xie, J. ...
Objectives. We attempted to determine whether elevated levels of the classic coronary heart disease risk factors are associated with increased coronary risk and all-cause mortality among elderly men with and without coronary heart disease at baseline. Methods. The classic coronary risk factor levels and risk of coronary events and total...
BackgroundCurrent guidelines do not recommend routine cardiac stress testing in patients with stable coronary heart disease (CHD) unless they report symptoms of
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The Treating to New Targets (TNT) trial compared atorvastatin 80 mg (aiming at reducing LDL cholesterol | or = 75 mg/dl) and atorvastatin 10 mg (LDL | or = 100 mg/dl as target) in 10,001 patients with stable coronary heart disease followed up for 5 years. A reduction of major cardiovascular events of 22% was observed in the atorvastatin 80 mg group as compared to the atorvastatin 10 mg group (hazard ratio: 0.78; 95 % interval of confidence: 0.69-0.89; p | 0.001). Such clinical efficacy was obtained while a good drug safety profile was maintained. Total mortality was not significantly different between the two groups. However, and remarkably, cardiovascular death was not the first cause of death anymore in this atorvastatin-treated population. The results of TNT in patients with stable coronary heart disease thus confirm the results of PROVE-IT in patients with acute coronary syndrome. These two randomised controlled trials should encourage considering a LDL cholesterol level of 75 mg/dl (rather than
A high body mass index (BMI) is associated with an increased risk of mortality from coronary heart disease (CHD); however, a low BMI may also be associated with an increased mortality risk. There is limited information on the relation of incident CHD risk across a wide range of BMI, particularly in women. We examined the relation between BMI and incident CHD overall and across different risk factors of the disease in the Million Women Study. 1.2 million women (mean age = 56 years) participants without heart disease, stroke, or cancer (except non-melanoma skin cancer) at baseline (1996 to 2001) were followed prospectively for 9 years on average. Adjusted relative risks and 20-year cumulative incidence from age 55 to 74 years were calculated for CHD using Cox regression. After excluding the first 4 years of follow-up, we found that 32,465 women had a first coronary event (hospitalization or death) during follow-up. The adjusted relative risk for incident CHD per 5 kg/m2 increase in BMI was 1.23 (95%
Lifestyle and risk factor results clearly demonstrate a challenging gap between what is recommended in scientific guidelines and what is achieved in daily practice in high risk individuals in primary prevention of CVD.. Primary prevention of heart disease needs a comprehensive, multidisciplinary approach involving the high-risk population, their GPs and other health professionals, a health insurance system dedicated to prevention and all this complemented by a population strategy involving the community at large.. The European Society of Cardiology together with other partner Societies has engaged in a comprehensive programme of prevention of cardiovascular disease (CVD) since 1994. Guidelines on this important topic have been developed and updated at regular intervals over the last 13 years, most recently in 2007. The implementation of these guidelines is facilitated by the Joint European Prevention Committee and the new European Association for Cardiovascular Prevention and Rehabilitation ...
DALLAS, TX -The American Heart Association (AHA) and Verily, (formerly Google Life Sciences) announced today that AstraZeneca (AZ) has joined them in a bold new approach to find a cure for coronary heart disease and improve cardiovascular health. With a commitment of $75 million dollars over at least a five year period, the three organizations have initiated the single largest research project funding one leader and team in the fight to cure coronary heart disease. The application period for this new research enterprise officially opens today at 5:00 PM ET at: www.onebraveidea.com. The three organizations have joined forces to find one brave idea from a visionary leader. This person and their team will be awarded the opportunity and challenge to make a difference for the millions of people directly affected by coronary heart disease. Their goal: prevent or reverse coronary heart disease and its consequences, therein restoring cardiovascular health. Launched as One Brave Idea™, this research ...
Treating depression in those with coronary heart disease: CODIACS Vanguard Randomized Controlled Trial. NEW YORK - Depressive symptoms after heart disease are associated with a markedly increased risk of death or another heart attack. However, less has been known about whether treating heart attack survivors for depressive symptoms could relieve these symptoms, be cost-effective, and ultimately, reduce medical risk? Columbia University Medical Centers Karina W. Davidson, PhD and her research team now report a patient-centered approach that answers these questions in the affirmative.. With a grant from the National Institutes of Healths National Heart, Lung, and Blood Institute (NHLBI), Dr. Karina Davidson, director of the Center for Behavioral Cardiovascular Health at CUMC, and her team completed a randomized controlled trial with 150 patients with elevated depressive symptoms two to six months after hospitalization for heart disease. Patients were recruited from seven centers across the ...
TY - JOUR. T1 - Can non-medical factors contribute to disparities in coronary heart disease treatments?. AU - Barnhart, Janice M.. AU - Cohen, Oshra. AU - Wright, Natania. AU - Wylie-Rosett, Judith. PY - 2006/8/1. Y1 - 2006/8/1. N2 - Racial/ethnic and sex disparities in coronary heart disease treatment exist. We previously reported that physicians perceive non-clinical variables, such as a patients desire for a second opinion, as affecting revascularization decisions. The results of that study are further examined here, using factor analysis to identify significant interrelationships among the non-clinical variables, which could contribute to disparities in coronary revascularization (i.e., percutaneous transluminal coronary angioplasty [PTCA] or coronary artery bypass graft [CABG]). Five content themes emerged using factor analysis; these are related to the patients socioeconomic/lifestyle status, treatment preference, physician interaction, health-assertiveness, and aggressiveness. For the ...
Coronary heart disease (CHD) is when your coronary arteries become narrowed by a gradual build-up of fatty material within their walls called atherosclerosis. These arteries supply your heart muscle with oxygen-rich blood. The most common symptom of coronary heart disease (CHD) is chest pain.. You can also experience other symptoms, such as a light headed sensation, palpitations and shortness of breath. Some people may not have any symptoms before they are diagnosed.. Your arteries may become so narrow that they cannot deliver enough oxygen-rich blood to your heart. The pain and discomfort you may feel as a result is called angina.. If a piece of atheroma breaks off it may cause a blood clot to form. If it blocks your coronary artery and cuts off the supply of oxygen-rich blood to your heart muscle, your heart may become permanently damaged. This is known as a heart attack.. There are several ways you can help reduce your risk of developing coronary heart disease (CHD), such as lowering your ...
In the article by Williams et al, "Is Optimal Medical Therapy "Optimal Therapy" for Multivessel Coronary Artery Disease?: Optimal Management of Multivessel Coronary Artery Disease," which appeared in the September 7, 2010 issue of the journal (Circulation 2010;122:943-945), there were two typographical errors:. On page 943, in the fourth paragraph "Coronary Artery Surgical Study" should read "Coronary Artery Surgery Study.". In the same paragraph, "European Coronary Surgical Study" should read "European Coronary Surgery Study.". The text has been corrected in the current online version of the manuscript. The authors regret the error.. ...
Baseline characteristics were compared between people with and without a family history of premature CHD. A Student t test was used for continuous variables (age, body mass index, waist circumference, waist/hip ratio, systolic and diastolic blood pressure, total cholesterol, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol) a χ2 test was used for categorical variables (sex, smoking status, diabetes mellitus). Because triglycerides and the FRS were not normally distributed, these parameters were log-transformed. The log-transformed variables were normally distributed and were compared using a Student t test.. The Framingham risk score was calculated using a previously reported algorithm, which takes into account age, sex, total cholesterol, HDL cholesterol, systolic and diastolic blood pressure, smoking and the presence of diabetes. Since the FRS overestimates CHD risk in Europeans, and more specifically in the EPIC-Norfolk study population, we recalibrated ...
Psychosocial characteristics have been linked to coronary heart disease. In the Belgian Job Stress Project (1994-1999), the authors examined the independent role of perceived job stress on the short-term incidence of clinical manifest coronary events in a large occupational cohort. A total of 14,337 middle-aged men completed the Job Content Questionnaire to determine the dimensions of the extended job strain model, job demands, decision latitude, and social support. Jobs were categorized into high strain, low strain, active jobs, and passive jobs. During the 3-year follow-up, 87 coronary events were registered. At baseline, 17% of workers experienced high strain. Job demands and decision latitude were not significantly related to the development of coronary heart disease after adjustment for covariates. The 38% risk excess among subjects classified in the high-strain category did not reach statistical significance. However, coronary heart disease incidence was substantially associated with the ...
Background: Lifestyle changes and drug treatment can improve the prognosis and quality of life for patients with coronary heart disease (CHD), but their co-operation with suggested treatment is often limited. The aim of this thesis was to study how patients and their spouses conceive CHD and its treatment.. Material and Methods: The research design used was inductive and descriptive. The studies were based on three complementary sets of data. Patients with CHD (n=23) and spouses (n=25) were interviewed one year after an episode of the disease. Consecutive patients with CHD derived from another investigation were interviewed within six weeks or one year after the coronary event (n=113). All semi-structured interviews, tape-recorded or from notes taken by hand, were subjected to analysis within the phenomenographic framework.. Findings: The patients conceptions of CHD varied and were vague, even as judged on a lay level. They were associated with symptoms rather than with the disease. ...
Linköping University, Faculty of Health Sciences. Linköping University, Department of Medical and Health Sciences, Division of Cardiovascular Medicine. Östergötlands Läns Landsting, Heart and Medicine Center, Department of Cardiology in Linköping. ...
Many patients with coronary disease and a positive exercise test have episodes of ST-segment depression during ambulatory monitoring, the majority of which are silent.42 43 44 45 46 47 48 49 Surprisingly, ambulatory ischemia monitoring has not been widely applied in the assessment of asymptomatic ischemia in diabetics. Chiariello et al15 compared the incidence of ambulatory ischemia during 24-hour AECG monitoring among 51 patients with diabetes (74% of whom had evidence of coronary disease), 70 nondiabetic patients with coronary disease, and 40 nondiabetic patients without overt coronary disease. They reported that 36% of the diabetic patients had at least one episode of asymptomatic ischemia, significantly higher than the 17% of patients in the nondiabetic group with coronary disease. Additionally, 73% of the total episodes of ST-segment deviation in the diabetic group were asymptomatic, significantly higher than the 60% of episodes in the nondiabetic group. These data cannot be directly ...
We have found that both mean and maximum measurements of CCA and ICA IMT are heritable. Heritability estimates using correlation coefficients and variance components methods are similar, and the magnitude of heritabilities for carotid IMT is similar to those reported for other quantitative cardiovascular traits such as systolic blood pressure and serum cholesterol. These data suggest that a substantial proportion of the variability in carotid IMT is explained by genetic factors.. Carotid IMT is a marker of subclinical cardiovascular disease that has been shown to be associated with traditional coronary heart disease risk factors3-6 and coronary atherosclerotic burden7,8 and to be predictive of subsequent cardiovascular events.9,10 Multiple prior studies have demonstrated the contribution of genetic factors to individual coronary heart disease risk factors, including systolic blood pressure,23 HDL cholesterol,24 and diabetes mellitus.25 A large study of 21 000 twins demonstrated an increased risk ...
Coronary heart disease remains a leading cause of mortality in the United States, with 84 percent of persons 65 years or older dying from this disease. Secondary preventive measures, including lifestyle modification and pharmacotherapy, are important for elderly patients because of the variable impacts on morbidity and mortality rates and quality of life. Participating in light to moderate activities significantly decreases mortality rates in elderly patients. Smoking cessation translates into a reduction in overall mortality and morbidity rates at least equal to that of other preventive measures such as aspirin or beta-blocker therapy. Recent studies on the effects of lowering low-density lipoprotein cholesterol levels to below 100 mg per dL have shown a substantial reduction in coronary heart disease mortality and nonfatal myocardial infarction rates, with a persistent effect in patients older than 75 years. Hypertension, manifesting mostly as isolated systolic blood pressure elevation, also should be
Coronary heart disease is a preventable disease in many patients. Prevention requires meeting specific treatment targets to address each patients risk factors. As I counsel my patients, I find that meeting these targets is often challenging. New medications and public health campaigns have led to significant reductions in cholesterol levels and rates of smoking? two of the major risk factors for coronary heart disease. Despite this progress, a recent study presented at the American Heart Associations Scientific Sessions 2009 suggests any strides forward have been tempered by a rise in the rates of obesity in the U.S. population. The result, according to the studys lead investigator: no net improvement in reducing the overall risk profile for coronary heart disease over the past 20 years.. ...
Results 1. Genotypes and frequencies of P2Y12 gene polymorphisms (rs9859552) in control group and coronary heart disease group both were GG genotype.. 2. Genotypes and frequencies of P2Y12 gene polymorphisms (rs6801273) in control group and coronary heart disease group were as below: CC genotype 10.0% vs 13.7%; CT genotype 40.0% vs 44.5%; TT genotype 50.0% vs 41.8%. There was no significant difference between control group and coronary heart disease group (p=0.33).. ...
A new treatment available to combat valvular heart disease could be an opportunity to improve the care provided to those who would previously have been too ill for open heart surgery - and cut mortality rates in patients with the disease. Dr Mark De Belder explains.
Data & statistics on Heart Disease Death Rate by Race in Iowa: Heart Disease Death Rate by Race in Iowa, 2001-2005, Age-Adjusted Mortality: Heart Disease (Quad Cities Area by Race; 2001-2003 Deaths per 100,000 Population), Heart Disease Mortality Rates: 2000-2006...
Coronary heart disease is a common term for the buildup of plaque in the hearts arteries that could lead to heart attack. But what about coronary artery disease? Is there a difference? The short answer is often no - health professionals frequently use the terms interchangeably.However, coronary heart disease , or CHD, is actually a result of coronary artery disease, or CAD, said Edward Fisher, M.D., Ph.D., an American Heart Association volunteer who is the Leon H.
Low social position and South Asian ethnicity are both associated with increased risk of dying from coronary heart disease,1 2 but the impact of differential access to medical care on these inequalities remains uncertain. If access to coronary management matched coronary incidence, then low social position and South Asian ethnicity would be associated with higher rates of use. For social position, most studies,3-10 but not all,11-13 find the opposite-high social deprivation is associated with lower rates of coronary angiography and revascularisation. Several studies, mainly small and retrospective, report less aggressive treatment of South Asian people with coronary disease compared with white patients.14-22 Such potential healthcare disparities have stimulated calls in the United States and United Kingdom for remedial action.23 24. Three interrelated questions remain unanswered. Firstly, in a general population that exhibits social and ethnic differences in rates of coronary heart disease, do ...
BACKGROUND: The GENetIcs of sUbSequent Coronary Heart Disease (GENIUS-CHD) consortium was established to facilitate discovery and validation of genetic variants and biomarkers for risk of subsequent CHD events, in individuals with established CHD.. METHODS: The consortium currently includes 57 studies from 18 countries, recruiting 185,614 participants with either acute coronary syndrome, stable CHD or a mixture of both at baseline. All studies collected biological samples and followed-up study participants prospectively for subsequent events.. RESULTS: Enrollment into the individual studies took place between 1985 to present day with duration of follow up ranging from 9 months to 15 years. Within each study, participants with CHD are predominantly of self-reported European descent (38%-100%), mostly male (44%-91%) with mean ages at recruitment ranging from 40 to 75 years. Initial feasibility analyses, using a federated analysis approach, yielded expected associations between age (HR 1.15 95% ...
Learn more about Atherosclerosis and Heart Disease Prevention at Doctors Hospital of Augusta Coronary Artery Disease Coronary Heart Disease Uses Principal ...
Learn more about Atherosclerosis and Heart Disease Prevention at Doctors Hospital of Augusta Coronary Artery Disease Coronary Heart Disease Uses Principal ...
Learn more about Atherosclerosis and Heart Disease Prevention at Reston Hospital Center Coronary Artery Disease Coronary Heart Disease Uses Principal Proposed...
According to the Food and Drug Administration (FDA), the test - called the PLAC Test for Lp-PLA2 - has been cleared for use in both men and women with no history of heart disease, but studies have shown it is more accurate in predicting coronary heart disease risk (CHD) in women. News on NewsHub.org
RESULTS: The meta-regression analysis included 108 randomised trials involving 299 310 participants at risk of cardiovascular events. All analyses that adjusted for changes in low density lipoprotein cholesterol showed no association between treatment induced change in high density lipoprotein cholesterol and risk ratios for coronary heart disease deaths, coronary heart disease events, or total deaths. With all trials included, change in high density lipoprotein cholesterol explained almost no variability ...
The term "heart disease" refers to several types of heart conditions, the most common type of which is coronary heart disease (also called coronary artery disease). This occurs when plaque builds up in the arteries that supply blood to the heart. Coronary heart disease can cause heart attack, angina, heart failure, and arrhythmias. These conditions are also the leading cause of disability in the United States and prevent many folks from working and enjoying family activities. But there is good news; its preventable and controllable, and the tips offered by the CDC are a really good place to start.. Written by: Tricia Doane, FizzNiche Staff Writer. Есть игры с трехмерной графикой и эффектами. Есть игры о картах и ее друзей. Также вы найдете Веселую Обезьянку и ее друзей. Также есть посвященные сериалам и фильмам. Довольно популярны сейчас ...
The ETT can be used to investigate coronary heart disease (sometimes called coronary artery disease). This disease is due to narrowing of the coronary arteries. It can cause chest pains (angina) and other problems. So, if you develop chest pains you may be advised to have an ETT to help clarify the cause. However, different investigations (eg, coronary angiography or myocardial perfusion scintigraphy) are now preferred to diagnose whether you have coronary heart disease.. Many people with coronary heart disease have a normal ECG at rest. During exercise the heart beats faster and needs more oxygen. If one or more of your coronary arteries are narrowed, part or parts of the heart muscle do not get enough oxygen. This can cause the ECG tracing to become abnormal when you exercise. Therefore, if you have a positive ETT (an abnormal reading) you are likely to have coronary heart disease.. If you already have coronary heart disease, the degree of abnormality on the ECG tracing from the ETT can give a ...
Lp(a) is an independent risk factor for recurrent atherosclerotic heart disease in men and women after menopause. Excess levels of Lp(a) are seen in both males and females, more common in Africans, African Americans, and Asian populations than in whites. Since the standard lipid profile does not report Lp(a), it has to be ordered separately. Screening for Lp(a) should be considered under the following circumstances: (a) patient or family history of premature atherosclerotic heart disease, (b) familial history of hyperlipidemia, (c) established atherosclerotic heart disease with a normal routine lipid profile, (d) hyperlipidemia refractory to therapy, and (e) history of recurrent arterial stenosis. Treatment options are (a) a new extended-release form of niacin 3 to 4 g daily (although most effective in lowering Lp(a) and in reducing atherosclerotic heart disease mortality rates, its use may be limited because of side effects); (b) estrogen replacement after menopause, (however, concomitant ...
Lp(a) is an independent risk factor for recurrent atherosclerotic heart disease in men and women after menopause. Excess levels of Lp(a) are seen in both males and females, more common in Africans, African Americans, and Asian populations than in whites. Since the standard lipid profile does not report Lp(a), it has to be ordered separately. Screening for Lp(a) should be considered under the following circumstances: (a) patient or family history of premature atherosclerotic heart disease, (b) familial history of hyperlipidemia, (c) established atherosclerotic heart disease with a normal routine lipid profile, (d) hyperlipidemia refractory to therapy, and (e) history of recurrent arterial stenosis. Treatment options are (a) a new extended-release form of niacin 3 to 4 g daily (although most effective in lowering Lp(a) and in reducing atherosclerotic heart disease mortality rates, its use may be limited because of side effects); (b) estrogen replacement after menopause, (however, concomitant ...
Associations between Interleukin-1 Gene Polymorphisms and Coronary Heart Disease Risk: A Meta-Analysis. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Kannel, W.B. and Lavine, B.S. (2003) Coronary Heart Disease Risk in People 65 Years of Age and Older. Progress in Cardiovascular Nursing, 18, 135-140.
Be aware of Coronary Artery Disease (CAD) that represents 1 out of 3 deaths in women. Learn more on Coronary Heart Disease (CHD) in women.
Investigate the possibility that family history beyond early-onset coronary heart disease might contribute to coronary heart disease susceptibility, the authors studied associations between additional family history and the coronary artery calcium score.
Cardiovascular Disease Cardiovascular disease is defined as medical conditions affecting the cardiovascular system, including heart, blood vessels(arteries and veins). I. Coronary heart disease Coronary heart disease is defined as a condition of narrowing coronary arteries that lead to blockage of the blood flow in the arteries as a result of hardening arterial wall, cholesterol building …. ...
In familial hypercholesterolemia (FH) elevated Lp(a) concentrations are more frequent than in the general Caucasian population, but the clinical relevance of Lp(a) as a risk-factor in this group of patients is controversial. In 91 adult patients with heterozygous FH due to LDL-receptor defect we analyzed the correlation between Lp(a) concentrations, presence of coronary heart disease (CHD) and degree of atherosclerosis of the carotid arteries assessed by duplex scan. Coronary heart disease was present in 32 patients (24 males, 8 females). In the group without CHD the median of the Lp(a) distribution was 23 mg/dl, in the group with CHD 43 mg/dl (P | 0.05). The median of Lp(a) was 8 mg/dl in patients without pathological changes in the duplex scan of the carotids, 13 mg/dl in the group with intimal thickening, 25 mg/dl in patients with non-obstructing plaques, and 45 mg/dl in presence of | 30% luminal obstruction (P | 0.01). The role of Lp(a) as an independent risk factor was analyzed by stepwise logistic
The researchers identified that the longer hours participants worked, the extra probably they had been to create CHD within 10 years, states a recent article in the Medical News Today. Fine Treatment recommends Dr. Allens Device for Heart Treatment to use daily, including working hours, for the treatment of CHD, just when people experience discomfort in chest or angina, to prevent a heart attack and improve their heart muscle condition.. A recent article, Long working hours linked to increased risk of coronary heart disease, dated September 16, 2014, in the Medical News Today, states, "According to a recent poll, 18% of adults employed full-time in the US work more than 60 hours a week. Although these long hours may benefit pay packets, the same may not be said for heart health; a new study suggests long working hours may increase the risk of coronary heart disease." These who worked 61-70 hours a week were at 42% greater threat of CHD than these who worked 31-40 hours a week.. In this study, ...
Bhopal R, Unwin N, White M, Yallop J, Walker L, Alberti KGMM, Harland J, Patel S, Ahmad N, Turner C, Watson B, Kaur D, Kulkarni A, Laker M, Tavridou ...
So, what causes a person to have coronary heart disease? First off, CHD is usually caused due to a build-up of fatty deposits on the walls of the arteries around the walls of the heart of a person suffering this disease. Due to this build-up, the blood flow is restricted making it hard for the heart to function normally.. Of course, your lifestyle has something to do with it such as being obese or overweight, smoking, and lack of physical activity. This is actually a series of consequences, take the lack of physical activity or exercise as an example, due to lack of exercise and unbalanced diet, you may be overweight which then would lead to either diabetes or high blood cholesterol level.. Another unhealthy lifestyle is smoking, this is a major risk factor for coronary heart disease since both nicotine and carbon monoxide puts a strain on the heart by making it work faster than normal, increasing your risk of blood clots. The other chemicals that can be found in cigarettes also contribute by ...
TY - JOUR. T1 - Association of Circulating Metabolites With Risk of Coronary Heart Disease in a European Population. T2 - Results From the Biomarkers for Cardiovascular Risk Assessment in Europe (BiomarCaRE) Consortium. AU - Cavus, Ersin. AU - Karakas, Mahir. AU - Ojeda, Francisco M. AU - Kontto, Jukka. AU - Veronesi, Giovanni. AU - Ferrario, Marco Mario. AU - Linneberg, Allan. AU - Jørgensen, Torben. AU - Meisinger, Christa. AU - Thorand, Barbara. AU - Iacoviello, Licia. AU - Börnigen, Daniela. AU - Woodward, Mark. AU - Schnabel, Renate. AU - Costanzo, Simona. AU - Tunstall-Pedoe, Hugh. AU - Koenig, Wolfgang. AU - Kuulasmaa, Kari. AU - Salomaa, Veikko. AU - Blankenberg, Stefan. AU - Zeller, Tanja. PY - 2019/10/30. Y1 - 2019/10/30. N2 - Importance: Risk stratification for coronary heart disease (CHD) remains challenging because of the complex causative mechanism of the disease. Metabolomic profiling offers the potential to detect new biomarkers and improve CHD risk assessment.Objective: To ...
How to distinguish the authenticity of coronary heart disease,Some preliminary judgment is coronary heart disease, mainly to see what aspects?1, from the patients symptoms, angina pectoris of coronary
Background: Persistent inflammation has been proposed to contribute to various stages in the pathogenesis of cardiovascular disease. Interleukin-6 receptor (IL6R) signalling propagates downstream inflammation cascades. To assess whether this pathway is causally relevant to coronary heart disease, we studied a functional genetic variant known to affect IL6R signalling.. Methods: In a collaborative meta-analysis, we studied Asp358Ala (rs2228145) in IL6R in relation to a panel of conventional risk factors and inflammation biomarkers in 125 222 participants. We also compared the frequency of Asp358Ala in 51 441 patients with coronary heart disease and in 136 226 controls. To gain insight into possible mechanisms, we assessed Asp358Ala in relation to localised gene expression and to postlipopolysaccharide stimulation of interleukin 6.. Findings: The minor allele frequency of Asp358Ala was 39%. Asp358Ala was not associated with lipid concentrations, blood pressure, adiposity, dysglycaemia, or smoking ...
Heart Disease Treatment. Studies show this treatment effective when it comes to Heart Disease Prevention. Discover a treatment that works.
A new genetic test could help predict which individuals will develop coronary heart disease among those with similar conventional risk factors. The length of the terminating structures of chromosomes, telomeres, can be used to predict cardiovascular mortality in middle-aged men, according to a study from Leicester in the UK which analysed blood samples collected for the West of Scotland Primary Prevention Study, (WOSCOPS). Nilesh Samani gave Helen Morant the details ...
Robert Clarke and colleagues conduct a meta-analysis of unpublished datasets to examine the causal relationship between elevation of homocysteine levels in the blood and the risk of coronary heart disease. Their data suggest that an increase in homocysteine levels is not likely to result in an increase in risk of coronary heart disease.
Coronary heart disease (CHD) is the most common cause of death in the UK. Learn about the Epidemiology of Coronary Heart Disease.
Sometimes, one may feel the heart pounds, flutters, or seem to skip beats. These are called palpitations that may be bothersome or even frightening, but most of them are not serious and seldom require treatment. They often go away on their own. Most of the time, they are caused by stress and anxiety, or because one had too much caffeine, nicotine, or alcohol. ...
Cigarette smoking can harm almost every organ of the body and reduce the health of smokers in general. Smokers can eventually develop many diseases, including lung cancers, heart disease, high blood pressure, stroke and chronic obstructive pulmonary disease (COPD). So nearly every nation in the world have been trying very hard to reduce the smoking rates. ...
Free medicine essay example on coronary heart disease: definition and strategies to identify the risk factors on Essays Professors.
Clinicians guide to lipids and coronary heart disease , Clinicians guide to lipids and coronary heart disease , کتابخانه دیجیتال دانشگاه علوم پزشکی اصفهان
Smoking Causes Coronary Heart Disease on Stop Smoking Tips | According to the National Institute of Health, coronary heart disease is the most common type of…
Information about coronary heart disease. Read our content about coronary heart disease symptoms, which include trouble breathing, and the ways to treat it.
The article presents the results of the study on the effect of a three-month application of «Theraflex®» in the complex therapy of comorbid pathology - osteoarthritis of the knee joints in combination with coronary heart disease. The positive drug effect on the symptoms of the combined pathology, both gonarthrosis and coronary heart disease, is shown. A conclusion is made about the active influence of «Theraflex®» on the pathogenetic mechanisms of gonarthrosis progression.. ...
How does malnutrition lead to coronary heart disease - How does malnutrition lead to coronary heart disease? Answered. Already answered.
For decades, your odds of suffering a heart attack were based on your cholesterol numbers, but the nations first new heart disease prevention guidelines in a decade focus more broadly on risk factors.
Preventive Cardiology Inc. has a number of resources to help you learn more about heart disease prevention. Visit our website for more information!
Miller M.; Martos J.; Kwiterovich P.O.Jr; Pearson T.A., 1990: Low levels of hdl predict subsequent coronary events in men with coronary disease and desirable cholesterol levels
Learn more about Atherosclerosis and Heart Disease Prevention at Medical Center of Aurora Natural TherapiesHerbs and Supplements to Be Used With Cautionrevision ...
Heart Disease Prevention at Sutter Pacific. Learn more about our services and how we partner with you to create personalized care.
Changes in coronary care and secondary prevention were strongly linked with declining coronary endpoints. Scores and benefits followed a geographical east-to-west gradient. The apparent effects of the treatment might be exaggerated by other changes in economically successful populations, so their sp …
However, women more often experience subtle, atypical signs - fatigue, shortness of breath, discomfort in the chest or upper body and pain in the abdominal region - that frequently mimic heartburn and other health problems.. Other Gender Differences in Heart Disease. On average, women with coronary heart disease are 10 years older than men who have the disease. Women also are more likely to have multiple risk factors (such as diabetes and vascular disease) and to have silent heart attacks. They are more likely to experience sudden death than men.. Medical research has shown that early mortality (in-hospital or 30-day) after coronary artery bypass graft (CABG) surgery is greater in women than men.2-5 In an article published by Circulation in 2002, Vaccarino and coworkers found that although the death rate following bypass surgery was higher in women of all ages, sex differences were more pronounced in younger patients. Women under 50 years of age were three times more likely to die than men (3.4 ...
Coronary heart disease (CHD) or coronary artery disease occurs when a coronary artery clogs and narrows because of a buildup of plaque.
Lot of patients come to our OPD and ask us as to why they developed Coronary Artery Disease. Once I say that this is because of long standing diabetes and blood pressure, their immediate reply would be why they developed heart disease even though their sugar and pressure has been well under control for the past 10 years. So, that obviously means that taking medicines alone for the adequate control of sugar and pressure is not enough and you have to go beyond. This is called "Lifestyle Modification".. Dr. K.P.Suresh Kumar, Chief Cardiologist at Kauvery Hospital, talks about the importance of medicines, diet and physical activity to control Coronary Heart Disease.. ...
Coronary Artery Disease (CAD) and Coronary Heart Disease (CHD) can be used interchangeably, as one is the precursor to the other. In simple terms, Coronary He
The article by Azambuja & Duncan is a stimulus for rethinking cardiovascular disease (CVD) epidemiology. As the authors acknowledged, many individuals with atherosclerosis, a major component of the causal pathway for CVD, lack identifiable traditional risk factors. This is a reasonable argument for searching for other potential etiologies, and a potential infectious risk factor has recently gained strong support. The authors presented ecological evidence of an association between coronary heart disease mortality and influenza infection. If true, prevention of CVD could be substantially changed. However, as the authors stated, ecological analysis may have many flaws and epidemiological data lack robustness due to the many possible confounding factors. Thus, socioeconomic level is an important risk factor for CVD and also a strong potential confounder for the association between coronary heart disease mortality and influenza infection. Interestingly, as mentioned by Azambuja & Duncan, the high ...
This months public health achievement - the decline in deaths from coronary heart disease (CHD) and stroke (a.k.a., cardiovascular disease [CVD]) - is one that hits close to home for me. My maternal grandfather died of a heart attack and both my paternal grandparents have had heart attacks as well. My mom is on meds for high cholesterol, hypertension and diabetes (all risk factors for heart attack). My dad hasnt been tested, but Id be willing to bet that he has all of that too. With all this heart disease on both sides of my family, Im at high risk for getting it, so anything I can do to mitigate that risk, Im all for it!. Some random interesting things about the decline of CHD and stroke:. ...
Coronary heart disease (CHD) and myocardial infarction (heart attack) are the most lethal forms of CHD. The five major risk factors for CHD are...
Clinical guidelines have suggested that calculation of global CHD risk is a useful addition to the clinicians armamentarium to reduce the burden of CHD in the population. However, we found surprisingly little evidence that physician knowledge of global CHD risk currently translates into improved clinical outcomes. We found two fair quality studies that showed that physician knowledge of global CHD risk is associated with increased prescription of cardiovascular drugs in high risk (but not all) patients. Two additional fair quality studies showed no effect on their primary outcomes, but one was underpowered and the other focused on prescribing of lifestyle changes, rather than drugs whose prescribing might be expected to be targeted by risk level. One of these aforementioned studies showed improved blood pressure in high-risk patients, but no improvement in the proportion of patients at high risk, perhaps due to the high proportion of participants with baseline risks significantly exceeding the ...
Coronary heart disease (CHD) is now the leading cause of death and disability in almost all regions of the world. Despite recent declines in age-standardized death rates from CHD globally, the number of CHD deaths have been increasing due to a combination of growth in population numbers and their longevity. In addition, manifestation and outcome of CHD varies substantially between and within countries....
Coronary Heart Disease is plaque buildup in your arteries. Its known as hardening of the arteries, too. Arteries carry blood and oxygen to your heart.
A person with coronary heart disease has an accumulation of fatty deposits in the coronary arteries. These deposits narrow the arteries and can decrease or block the flow of blood to the heart.
A person with coronary heart disease has an accumulation of fatty deposits in the coronary arteries. These deposits narrow the arteries and can decrease or block the flow of blood to the heart.
A person with coronary heart disease has an accumulation of fatty deposits in the coronary arteries. These deposits narrow the arteries and can decrease or block the flow of blood to the heart.
A person with coronary heart disease has an accumulation of fatty deposits in the coronary arteries. These deposits narrow the arteries and can decrease or block the flow of blood to the heart.
A person with coronary heart disease has an accumulation of fatty deposits in the coronary arteries. These deposits narrow the arteries and can decrease or block the flow of blood to the heart.