TY - JOUR. T1 - Likelihood of obstructive coronary disease in metabolic syndrome patients with abnormal stress echocardiography. AU - Al Badarin, Firas J.. AU - From, Aaron M.. AU - McCully, Robert B.. AU - Lopez-Jimenez, Francisco. PY - 2011/10/20. Y1 - 2011/10/20. N2 - Background: Metabolic syndrome (MetSx) encompasses several risk factors for macrovascular coronary artery disease. An association between MetSx and coronary syndrome X has also been reported, suggesting that patients with MetSx are more likely to have endothelial dysfunction in the setting of angiographically normal coronary arteries. It remains unknown whether MetSx patients with abnormal stress echocardiography (SE) are more likely to have obstructive coronary disease (CAD) compared to patients without MetSx. Methods: We identified symptomatic patients without known CAD and abnormal SE who underwent coronary angiography within 4 weeks after the SE. Patients were grouped according to their MetSx and impaired fasting glucose ...

TY - JOUR. T1 - Metabolic syndrome and angiographic coronary artery disease prevalence in association with the framingham risk score. AU - Konstantinou, Dimitris M.. AU - Chatzizisis, Yiannis S.. AU - Louridas, George E.. AU - Giannoglou, George D.. PY - 2010/6/1. Y1 - 2010/6/1. N2 - Background: The association of metabolic syndrome with coronary artery disease (CAD) has been studied extensively. However, little is known about the effect of Framingham risk score (FRS) and metabolic syndrome components on the association of metabolic syndrome with angiographically significant CAD. Our aim was to investigate whether that relationship is influenced by individuals 10-year CAD risk profile as assessed by FRS. Furthermore, we sought to elucidate whether metabolic syndrome is associated with angiographically significant CAD independently of its individual components. Methods: We studied a consecutive sample of 150 patients undergoing coronary angiography for the evaluation of chest pain. Metabolic ...

TY - JOUR. T1 - Internal pudendal artery stenoses and erectile dysfunction. T2 - Correlation with angiographic coronary artery disease. AU - Rogers, Jason H. AU - Karimi, Houshang. AU - Kao, John. AU - Link, Daniel P. AU - Javidan, Javid. AU - Yamasaki, Dwayne S.. AU - Dolan, Mark. AU - Laird, John R.. AU - Low, Reginald. PY - 2010/11/15. Y1 - 2010/11/15. N2 - Objectives: To describe the angiographic characteristics of pelvic arterial disease in patients with erectile dysfunction (ED) nonresponsive to phosphodiesterase-5 inhibitors (PDE5i) and suspected coronary artery disease (CAD). Background: ED and CAD share common risk factors which can result in endothelial dysfunction, atherosclerosis and flow-limiting stenoses in the coronary and internal pudendal arteries. Methods: Ten patients undergoing cardiac catheterization with ED and a history of unsatisfactory response to a PDE5i were studied. ED severity was quantified using the International Index of ED scoring system. We performed angiography ...

OBJECTIVES: This study sought to ascertain the relationship of 9p21 locus with: 1) angiographic coronary artery disease (CAD) burden; and 2) myocardial infarction (MI) in individuals with underlying CAD. BACKGROUND: Chromosome 9p21 variants have been robustly associated with coronary heart disease, but questions remain on the mechanism of risk, specifically whether the locus contributes to coronary atheroma burden or plaque instability. METHODS: We established a collaboration of 21 studies consisting of 33,673 subjects with information on both CAD (clinical or angiographic) and MI status along with 9p21 genotype. Tabular data are provided for each cohort on the presence and burden of angiographic CAD, MI cases with underlying CAD, and the diabetic status of all subjects. RESULTS: We first confirmed an association between 9p21 and CAD with angiographically defined cases and control subjects (pooled odds ratio [OR]: 1.31, 95% confidence interval [CI]: 1.20 to 1.43). Among subjects with angiographic CAD (n

BACKGROUND: Patients with obstructive left main coronary artery disease are usually treated with coronary-artery bypass grafting (CABG). Randomized trials have suggested that drug-eluting stents may be an acceptable alternative to CABG in selected patients with left main coronary disease. METHODS: We randomly assigned 1905 eligible patients with left main coronary artery disease of low or intermediate anatomical complexity to undergo either percutaneous coronary intervention (PCI) with fluoropolymer-based cobalt-chromium everolimus-eluting stents (PCI group, 948 patients) or CABG (CABG group, 957 patients). Anatomic complexity was assessed at the sites and defined by a Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery (SYNTAX) score of 32 or lower (the SYNTAX score reflects a comprehensive angiographic assessment of the coronary vasculature, with 0 as the lowest score and higher scores [no upper limit] indicating more complex coronary anatomy). The primary end point was

We have developed a novel approach that allows rapid computation of FFR during diagnostic coronary angiography. In the study population of 73 patients with intermediate coronary lesions in 84 vessels, the QFR showed good agreement with the pressure wire-determined standard FFR measurements. The agreement was particularly favorable with QFR derived from contrast-flow (cQFR) and adenosine-flow models (aQFR), which both incorporated patient-specific flow by frame count analysis. Positive and negative likelihood ratios were of diagnostic value for use in the individual patient with cQFR and aQFR, although the positive likelihood ratio was of insufficient diagnostic value to be clinically useful with fQFR and a DS% of ≥50% (21).. In this study, the vessel-based diagnostic accuracy for determining the functional significance of an intermediate stenosis (i.e., FFR ≤ 0.80) was only 65%, if based on a single 3D QCA anatomic parameter of diameter stenosis of ≥50%. This is in line with a recent study ...

Spontaneous coronary artery dissection (SCAD) is a rare but often fatal cause of ischaemic heart disease occurring predominantly in young or middle aged, otherwise healthy subjects. Although about 250 cases of SCAD have been reported in the literature, to the best of our knowledge, spontaneous three vessel coronary dissection associated with typical effort angina has never been reported. This case illustrates coronary angiography and intravascular ultrasound images in a patient with SCAD involving all three vessels and treated by stenting.. A 57 year old man presented with exertional chest pain. His risk factors included smoking, hypertension, and hyperlipidaemia. ECG showed an abnormal Q wave in lead III and 1 mm ST depression in III, aVF. Technetium-99m sestamibi SPECT image showed a moderate fixed defect in the inferior wall and a reversible defect in the anterior wall. Selective coronary angiography revealed SCAD involving all three vessels. Right coronary angiogram showed linear dissection ...

TY - JOUR. T1 - Noninvasive visualization of the left main coronary artery by cross sectional echocardiography. AU - Weyman, A. E.. AU - Feigenbaum, Harvey. AU - Dillon, J. C.. AU - Johnston, K. W.. AU - Eggleton, R. C.. PY - 1976. Y1 - 1976. N2 - Real time cross sectional echocardiographic studies of the left main coronary artery (LMCA) were performed in 15 normal patients, 15 patients with angiographically proven coronary artery disease but normal left main coronary segments, three patients with greater than 75% obstruction of the left main coronary artery, and one patient with a large aneurysm of the left main coronary artery. In normal subjects the LMCA evaginates from the inferolateral wall of the aorta. The artery appears as two dominant parallel linear echoes separated by a clear space representing the lumen of the vessel. The LMCA courses beneath the right ventricular outflow tract and can generally be followed to its expected point of bifurcation. Confirmation that this structure was in ...

Coronary dissection and total coronary occlusion leading to emergency coronary surgery are the most frequent complications of percutaneous transluminal coronary angioplasty (PTCA) and their occurrence usually is unpredictable. To identify angiographic characteristics of coronary stenoses that may affect the incidence of these complications, the diagnostic pre-PTCA coronary angiograms of 38 consecutive patients (group I) undergoing emergency coronary surgery for dissection or occlusion were reviewed and compared with the angiograms of a random sample of 38 patients (stratified for left anterior descending and right coronary arteries) from a group of 1151 who did not need emergency coronary surgery (group II). Stenosis morphology before angioplasty was considered complicated if at least one of the following criteria was present: irregular borders, intraluminal lucency, and localization of stenosis in curve or at bifurcation. Baseline characteristics, maximum inflation pressures, types of balloon ...

BACKGROUND: In patients with non-ST-segment elevation acute coronary syndrome (NSTEACS), coronary pathology may range from structurally normal vessels to severe coronary artery disease.. OBJECTIVES: The purpose of this study was to test if coronary computed tomography angiography (CTA) may be used to exclude coronary artery stenosis ≥50% in patients with NSTEACS.. METHODS: The VERDICT (Very Early Versus Deferred Invasive Evaluation Using Computerized Tomography in Patients With Acute Coronary Syndromes) trial (NCT02061891) evaluated the outcome of patients with confirmed NSTEACS randomized 1:1 to very early (within 12 h) or standard (48 to 72 h) invasive coronary angiography (ICA). As an observational component of the trial, a clinically blinded coronary CTA was conducted prior to ICA in both groups. The primary endpoint was the ability of coronary CTA to rule out coronary artery stenosis (≥50% stenosis) in the entire population, expressed as the negative predictive value (NPV), using ICA as ...

BACKGROUND: In patients with non-ST-segment elevation acute coronary syndrome (NSTEACS), coronary pathology may range from structurally normal vessels to severe coronary artery disease.. OBJECTIVES: The purpose of this study was to test if coronary computed tomography angiography (CTA) may be used to exclude coronary artery stenosis ≥50% in patients with NSTEACS.. METHODS: The VERDICT (Very Early Versus Deferred Invasive Evaluation Using Computerized Tomography in Patients With Acute Coronary Syndromes) trial (NCT02061891) evaluated the outcome of patients with confirmed NSTEACS randomized 1:1 to very early (within 12 h) or standard (48 to 72 h) invasive coronary angiography (ICA). As an observational component of the trial, a clinically blinded coronary CTA was conducted prior to ICA in both groups. The primary endpoint was the ability of coronary CTA to rule out coronary artery stenosis (≥50% stenosis) in the entire population, expressed as the negative predictive value (NPV), using ICA as ...

Background: Coronary artery disease is sometimes associated with chronic conduction block. Our aim is to correlate between chronic conduction block and coronary artery disease. We performed ECG and coronary angiography of all patients who were admitted for permanent pacemaker implantation to find correlation between them. Methods: Coronary angiography was performed in all 160 patients of chronic conduction block during twenty four months of study period who were admitted for pacemaker implantation. We compared the coronary artery disease in different types of conduction block. Results: Among the study population 35(22%) patients are of single vessel coronary artery disease (CAD),13 (8%) patients had double vessel coronary artery disease, 6 (4%) patients had triple vessel coronary artery disease, 2 (1%) patients had left main disease and 104 (65%) patients had normal or insignificant coronary anatomy. Conclusion: Coronary artery disease is quite common in chronic conduction disorder. So there ...

Endogenous oxidative DNA damage is caused by multiple endogenous and exogenous factors. It is not completely known whether coronary angiography has an effect on DNA damage. The aim of this study was to investigate whether coronary angiography causes oxidative DNA damage. Fifty-four patients who underwent elective coronary angiography for diagnostic purpose were enrolled to the study. For each subject, the frequency of oxidative DNA damage was analyzed by using the comet assay, which is a sensitive biomarker of DNA damage, before and after diagnostic procedures. A highly significant increase of DNA damage mean score was observed in all patients after the coronary angiography procedure (p < 0.001). No significant associations were found between the change in oxidative DNA damage and dose of contrast media and radiation exposure time. A significant correlation was observed between the change of DNA damage and age, hyperlipidemia, hypertension, smoking, Gensini score index, and vitamin B,2 (r = ...

As coronary angiography became more widely practiced in the 1960s, it was soon apparent that not all patients with clinical suspicion of coronary artery disease (CAD) had obstruction of epicardial coronary arteries. Several published series, including the National Heart, Lung, and Blood Institute-sponsored CASS (Coronary Artery Surgery Study) and the WISE (Womens Ischemia Syndrome Evaluation) study, have reported that up to one-half of patients undergoing coronary angiography are found to have normal or nonobstructed epicardial coronary arteries (1-3). In 1967, Likoff et al. (4) reported on 15 women ranging in age from 30 to 53 years with chest pain despite normal coronary angiograms (CPNCA), but with electrocardiographic (ECG) abnormalities at rest (ST-segment depression or T-wave inversion) that were accentuated by exercise. Despite the ECG changes during exercise, the hemodynamic response-as assessed by pulmonary artery pressure, cardiac output, and oxygen consumption-was reported as normal ...

Background and Purpose: Acute myocardial infarction(AMI) occurs in 1-2% of patients treated with carotid artery stenting(CAS), and is considered as one of the most serious perioperative complication. We assessed coronary artery stenosis in patients treated with CAS using coronary CTA or coronary angiography.. Methods: Consecutive sixty-two patients (47 men, mean age 73.4 years) treated with CAS were examined by coronary CTA or angiography within 3 months before CAS between January 2010 and August 2012. In patients suspected coronary artery stenosis by coronary CTA, coronary angiography was performed. Significantly coronary artery stenosis was defined as that greater than 75%.. Results: CAS was performed in 62 patients, and coronary artery was evaluated in 57 patients. Patients with allergic reaction for contrast agents, renal failure, and poor general condition were excluded from this study. Thirty-eight patients had significant coronary artery stenosis. Twenty-nine of them had any history of ...

Definition of Left main coronary artery in the Legal Dictionary - by Free online English dictionary and encyclopedia. What is Left main coronary artery? Meaning of Left main coronary artery as a legal term. What does Left main coronary artery mean in law?

The role of vaspin in the pathogenesis of stable coronary artery disease (SCAD) have been repeatedly addressed in clinical studies. However, from the point of view of clinical practice, the results of earlier studies are still inconclusive. The data of 106 SCAD patients who received coronary angiography and 85 coronary artery disease-free controls were collected and analysed. The patients were divided into subgroups according to their pre-test probability (PTP) and according to the result of coronary angiography. Fasting vaspin concentrations were compared between subgroups of SCAD patients and between target group and controls. The effect of age and smoking on the result of coronary angiography was compared to the effect of vaspin using the binomial regression. We did not find significant difference in vaspin level between target group and controls. Unless the pre-test probability was taken into account, we did not find vaspin difference in the target group, when dividing patients on the basis of

Background: Although a shorter hemostasis duration would be expected when compared with the conventional radial approach as the diameter of the distal radial artery is smaller than that of the conventional radial artery, the optimal duration of hemostasis in diagnostic coronary angiography (CAG) via the distal radial approach, termed the snuffbox approach, has not been well investigated. Methods: Data from 171 patients were retrospectively collected (55 and 116 patients in the 4-French [Fr] and 5-Fr sheath groups, respectively). The patients had suspected myocardial ischemia and were undergoing diagnostic CAG via the snuffbox approach at a single center between January 2019 and August 2019. Results: The mean age of the study population was 67.6 ± 11.0 years, and 69% were male. The left snuffbox approach was performed in 146 (85.4%) patients. The mean snuffbox puncture time, defined as the time interval between local anesthesia and sheath cannulation, was 145.1 ± 120.8 s. The hemostasis ...

Purpose: Percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) is still one of the challenging procedures. Multislice computed tomographic coronary angiography (CTCA) allows reliable non-invasive evaluation of coronary artery by visualizing calcium deposit, vessel tortuosity, distal flow, etc. even in the occluded site. The aim of this study is to determine the morphological predictors of procedural success in PCI for CTO using CTCA, and to estimate the value of CTCA to predict procedural outcome.. Methods: Using Somatom Sensation Cardiac 64, we performed CTCA in 91 patients who have CTO prior to PCI, and 93 CTO lesions were scanned. CTO was defined as complete occlusion of a major coronary artery on catheter coronary angiography, which was deemed to be of , 3 months duration. Procedural success was defined as complete cross of the guidewire to the occluded site. Retrograde approach, in which the guidewire was advanced from the distal end of the occluded site through the ...

A boy aged 16 years and 10 months had typical Kawasaki disease diagnosed when aged 1 year and 8 months. Selective coronary angiography at the age of 5 years and 7 months showed a giant aneurysm (diameter 8.6 mm) on the right coronary artery (segment 2), and dilatation of the left circumflex artery (segment 11; diameter 7 mm). Although coronary angiography at age 8 years 3 months showed similar dilated lesions at segments 2 and 11, a new small dilated lesion with a diameter of 2.7 mm appeared at segment 4 (arrow). The dilated lesions at segments 2 and 11 were smaller at age 12 years and 4 months, and calcification was apparent in the aneurysm at segment 2. Two new aneurysms were observed at age 16 years and 10 months, one in the left anterior descending artery (segment 6), and the other in the right coronary artery proximal to the formerly existing aneurysm (arrow). Mild localised stenosis was detected at the proximal and distal ends of the aneurysm in segment 2. The aneurysm in segment 4 ...

Background The dimensions of the coronary arteries have been shown to vary among ethnic groups. There are no data available regarding the normal size of coronary arteries in Iranians. This study aimed to investigate normal coronary artery dimensions in a Northwestern Iranian population and to compare it with pooled data of Indo-Asians and Caucasians in previous studies. Methods The study included 200 adults with suspected coronary disease who were referred for elective coronary angiography between June 2012 and March 2013 and were found to have normal epicardial flow in the coronary arteries. Quantitative coronary angiography was carried out on the longest atheroma-free part of the proximal segment of each coronary artery in all patients. Two Indo-Asian and Caucasian groups were selected and pooled for comparison with the available reports on individuals without coronary artery disease. Results The mean diameters of the left main coronary artery, proximal left anterior descending artery, ...

BACKGROUND: Adverse cardiac event rates are higher for percutaneous coronary intervention (PCI) of bifurcation lesions. Currently, provisional stenting or a simple stenting strategy is the standard treatment for bifurcated lesions, but its performance remains limited because of a risk of side-branch (SB) closure and a higher rate of target lesion revascularization (TLR). We report a new provisional side-branch stenting strategy to treat coronary bifurcation lesions using a balloon-stent kissing technique (BSKT).. METHODS: From January 2011 to December 2012, a total of 60 patients with 60 bifurcation lesions underwent PCI using BSKT. Baseline and postprocedural quantitative coronary angiography (QCA) analyses were performed. Procedural and immediate clinical outcomes were reviewed.. RESULTS: The majority of patients presented with acute coronary syndrome (98%) and had true bifurcation lesions (98%). TIMI-3 flow was established in 100% of the main branch and SB lesions. QCA revealed preservation ...

Background: The aim of our study is to determine the incidence of single coronary artery (SCA). SCA is a rarely seen coronary anomaly in which the right coronary artery and the left main coronary artery arise from single aortic sinus. Although SCA has a benign course in most cases and its clinical significance is unknown, in some autopsy studies it was shown to be related to sudden cardiac death.. Materials and methods: SCA patients detected among 215,140 coronary angiographies (CAG) performed between 1998 and 2013 in SANKO Hospital were included in our study. The classification of CAG was made according to the two different classifications defined by Smith and Lipton and colleagues.. Results: A total number of 215,140 patients who underwent routine CAG were included in the study, and SCA was detected in 67 (0.031%) patients. There were 6 (9%) type R-I, 23 (34%) type R-II, 10 (15%) type R-III, 16 (24%) type L-I and 12 (18%) type L-II patients according to the angiographic ...

TY - JOUR. T1 - Variation among cardiologists in the utilization of right heart catheterization at time of coronary angiography. AU - Malone, Michael L.. AU - Bajwa, Tanvir K.. AU - Battiola, Richard J.. AU - Fortsas, Michael. AU - Aman, Saleem. AU - Solomon, David J.. AU - Goodwin, James S.. PY - 1996/2. Y1 - 1996/2. N2 - To describe how often a right heart catheterization was performed at the time of coronary angiography, the patient characteristics that predicted the use of this procedure, and the variation among cardiologists in the use of this test, we reviewed all cases of coronary angiography (n = 1,282) during the first 2 mo of 1993 at two large community hospitals. Fifty-two percent of the cases received a right heart catheterization at the time of their coronary angiography. The following characteristics were associated with the receipt of a right heart catheterization in a logistic regression analysis: cardiomyopathy (odds ratio = 2.59, 95% Cl = 1.01, 6.62), congestive heart failure ...

LMT compression may occur in patients with PAH with severely dilated PAs and can be identified with either computed tomographic coronary angiography or selective coronary angiography (1). There are several reports of the safety of stent implantation and resolution of typical angina in such patients (1,2). In patients with LMT compression, atypical symptoms, and no evidence of rest ischemia, further testing is warranted to assess the physiological significance of the stenosis. This is relevant in this context because coronary blood flow and subendocardial perfusion are diastolic events (3,4), and LMT compression from an enlarged PA is a systolic event; hence, not all such lesions lead to ischemia. Exercise stress testing is relatively contraindicated in patients with severe PAH, and vasodilator stress nuclear testing may miss global ischemia in patients with left main disease. Thus, instantaneous wave-free ratio and fractional flow reserve are best suited for evaluating stenosis significance in ...

BACKGROUND: Conventional coronary angiography (CA) is still recommended before valvular surgery. Preliminary studies suggest that multislice spiral computed tomography coronary angiography (MSCT-CA) can be used to rule out coronary artery disease (CAD). AIM: To assess prospectively the safety of ruling out CAD before surgery solely on the basis of normal MSCT-CA in patients with severe aortic valve disease. METHODS: We included all consecutive patients scheduled for aortic valve surgery. We first estimated the calcium score (Agatston score equivalent [ASE]). Patients underwent injected MSCT if the ASE was|1000. CA was cancelled when MSCT-CA quality was sufficient and showed no significant CAD. Our primary endpoint was the occurrence of perioperative myocardial infarction in patients who underwent surgery with no prior CA. RESULTS: Between 1st July 2005 and 30th June 2008, we included 199 patients with severe aortic valve disease: 118 men (59%); mean age 69+/-12 years; 63 patients (32%) underwent CA

TY - JOUR. T1 - Sequential follow-up results of catheter intervention for coronary artery lesions after Kawasaki disease. T2 - Quantitative coronary artery angiography and intravascular ultrasound imaging study. AU - Ishii, Masahiro. AU - Ueno, Takafumi. AU - Ikeda, Hisao. AU - Iemura, Motofumi. AU - Sugimura, Tetsu. AU - Furui, Jun. AU - Sugahara, Yoko. AU - Muta, Hiromi. AU - Akagi, Teiji. AU - Nomura, Yuichi. AU - Homma, Tomoki. AU - Yokoi, Hiroyoshi. AU - Nobuyoshi, Masakiyo. AU - Matsuishi, Toyojiro. AU - Kato, Hirohisa. PY - 2002/6/25. Y1 - 2002/6/25. N2 - Background - The purpose of this study was to assess the sequential follow-up results of catheter intervention in Kawasaki disease by use of quantitative coronary angiography (QCA) and intravascular ultrasound imaging. Methods and Results - Catheter intervention was performed on 23 stenotic lesions in 22 patients (aged 2 to 24 years). Percutaneous balloon angioplasty (PBA) was performed in 4 patients, stent implantation in 7, ...

Quantitation of coronary luminal diameter with a 20 MHz mechanically rotating intravascular ultrasound (IVUS) catheter was compared with orthogonal-view cineangiography by use of a semiautomated edge-detection algorithm in 48 patients undergoing coronary angioplasty. Quantitative comparison of 196 matched segments was attempted, but in only 174 (88.8%) was a direct comparison of the two techniques possible. In angiographically normal coronary arteries (46 segments) the correlation between the values obtained by quantitative coronary angiography (QCA) and those achieved by IVUS was excellent (r = 0.92, p , 0.0001). For mild stenoses (80 segments) the correlation coefficient was only fair (r = 0.467, p , 0.001). After percutaneous transluminal coronary angioplasty the correlation coefficient between IVUS and QCA data (48 segments) was very weak (r = 0.282, p , 0.05). In conclusion, coronary IVUS is feasible and safe and even for a limited range of coronary arterial narrowing, significant ...

AIMS:. To investigate whether the use of intravascular ultrasound virtual histology (IVUS-VH) leads to any improvements in stent deployment, when performed in patients considered to have had an optimal percutaneous coronary intervention (PCI) by quantitative coronary angiography (QCA).. METHODS AND RESULTS:. After optimal PCI result (residual stenosis by QCA,30%), IVUS-VH was performed in 100 patients by protocol, with the option to use the information left to the discretion of the operators. Patients were categorised as: Group1 (n=54), where the IVUS-VH findings were used to evaluate the need for further optimisation of the stent deployment; and Group2 (n=46), where the IVUS-VH was documentary such that the stenting results were considered optimal according to QCA. Optimal stent deployment on IVUS-VH was defined as: normal stent expansion, absence of stent malapposition, complete lesion coverage as indicated by a plaque burden (PB%) between 30-40% and necrotic core confluent to the lumen,10% or ...

Unhealthy lifestyle factors such as smoking, obesity, inactivity and type 2 diabetes are endemic in the Middle East. The public health consequences might be detrimental; however, local studies on risk factors for coronary artery disease (CAD) are scarce. Patients referred for coronary angiography at a tertiary hospital in Amman, Jordan, between January and December 2015, were included in this study. Risk factors for CAD were assessed in a multivariate logistic regression model, and presented as odds ratio (OR) with 95% confidence interval (CI). Among 557 participants, 356 (63.9%) had CAD and 201 (36.1%) had a normal cardiogram. The majority (n = 395, 70.9%) were male, and median age was 55 years (interquartile range 47-64). Two-hundred-and-fifteen (38.6%) individuals reported previous diabetes, and 287 (51.5%) were current or previous smokers. In multivariate analysis, male gender (OR 3.7, 95% CI 2.3-6.0), age (45-54 years: OR 4.8, 95% CI 2.7-8.5; 55-64 years: OR 6.0, 95% CI 3.2-11.4; ≥65 years: OR 15

OBJECTIVES: The aim of the present study was to evaluate, in low-to-intermediate pre-test probability patients who were referred for coronary computed tomography angiography (CTA) and did not show obstructive coronary artery disease (CAD), whether an intramural course of a coronary artery is associated with worse outcome compared with patients without an intramural course of the coronary arteries. BACKGROUND: The prognostic value of an intramural course of the coronary arteries on coronary CTA in patients without obstructive CAD is not well-known. METHODS: The study population consisted of 947 patients with a low-to-intermediate pre-test probability who were referred for coronary CTA and who did not have obstructive CAD. During follow-up, the occurrence of unstable angina pectoris that required hospitalization, nonfatal myocardial infarction, and all-cause mortality was evaluated. Results : On coronary CTA, 210 patients (22%) had an intramural course of a coronary artery. The median depth of the ...

Background: Renal insufficiency plays a critical role in the pathogenesis of ischemic heart disease. The aim of the present study was to investigate the prevalence of renal dysfunction and its impact on prognosis in patients with left main coronary artery disease (LMCAD) and stable angina pectoris. Methods and Results: A total of 626 consecutive patients with significant coronary artery stenosis were enrolled. Renal insufficiency was graded using estimated glomerular filtration rate (eGFR) before coronary angiography. Chronic kidney disease (CKD) was defined as eGFR ...

Blockages prevent your heart from getting oxygen and important nutrients. This procedure is used to diagnose coronary heart disease and coronary microvascular disease after chest pain, sudden cardiac arrest, or abnormal results from tests such as an electrocardiogram (EKG) of the heart or an exercise stress test. It is important to detect blockages because over time they can cause chest pain, especially with physical activity or stress, or a heart attack. If you are having a heart attack, coronary angiography can help your doctors plan your treatment.. Cardiologists, or doctors who specialize in the heart, will perform coronary angiography in a hospital or specialized laboratory. You will stay awake so you can follow your doctors instructions, but you will get medicine to relax you during the procedure. You will lie on your back on a movable table. Often, coronary angiography is done with a cardiac catheterization procedure. For this, your doctor will clean and numb an area on the arm, groin or ...

CT Coronary Angiography Test Cost in Hyderabad. Packages starting for Angiogram test from Rs.12,500 at top hospitals. Compare quotes and book appointments online to avail discounts on Credihealth.

TY - JOUR. T1 - Feasibility of an automatic computer-assisted algorithm for the detection of significant coronary artery disease in patients presenting with acute chest pain. AU - Kang, Ki Woon. AU - Chang, Hyuk Jae. AU - Shim, Hackjoon. AU - Kim, Young Jin. AU - Choi, Byoung Wook. AU - Yang, Woo In. AU - Shim, Jee Young. AU - Ha, Jongwon. AU - Chung, Namsik. N1 - Funding Information: This work was supported by Industrial Strategic Technology Development Program, 10038419, Intelligent Image Diagnosis and Therapy-support System funded by the Ministry of Knowledge Economy (MKE, Republic of Korea).. PY - 2012/4. Y1 - 2012/4. N2 - Automatic computer-assisted detection (auto-CAD) of significant coronary artery disease (CAD) in coronary computed tomography angiography (cCTA) has been shown to have relatively high accuracy. However, to date, scarce data are available regarding the performance of auto-CAD in the setting of acute chest pain. This study sought to demonstrate the feasibility of an auto-CAD ...

In the past, two reliable methods leading to improvements in the accuracy of coronary angiography have been introduced. Interestingly, we demonstrated the first practical experience with intracoronary ultrasound more than a decade ago [5]. Since that time, virtual histology and optical coherence tomography have significantly improved our options for evaluation of coronary anatomy. Moreover, several studies have demonstrated that intravascular ultrasound guided interventions resulted in a reduced incidence of adverse clinical outcomes, especially in patients with proximal stenoses (left main coronary artery or proximal bifurcation lesions) [6]. On the other hand, evaluation of coronary anatomy and accurate morphology of coronary lesions have certain limitations, both with regard to hemodynamic significance and assessing the extent of ischemic myocardium, which is probably the key to choosing an optimal therapy. The only way currently to easily establish the hemodynamic significance of a ...

There are ,400,000 percutaneous transluminal coronary angioplasty (PTCA) procedures performed each year in the United States, at an estimated cost of 6 billion dollars ([1]). Health care providers are under intense pressure from third-party payers to reduce the cost associated with PTCA ([2]). One proposed cost reduction strategy is to perform PTCA at the time of the initial diagnostic catheterization (combined, ad hoc or add-on procedures [[3, 4]]). Along with the potential for decreasing length of hospital stay and costs ([3]), these combined PTCAs may also reduce the risk of peripheral vascular complications and patient exposure to radiation and contrast agents ([3]).. However, the potential benefits of performing combined procedures must be weighed against their possible risks. Performing PTCA immediately after a diagnostic procedure involves prolongation of the catheterization procedure and may not allow for as careful an assessment of the indications for or technical difficulty of ...

TY - JOUR. T1 - Usefulness of myocardial perfusion echocardiography to identify obstructive coronary artery disease in patients with abnormal ventricular septal motion. AU - Spevack, Daniel M.. AU - Shoyeb, Abu. AU - Yoon, Andrew J.. AU - Gordon, Garet M.. AU - Matros, Todd. AU - Reynolds, Harmony A.. AU - Shah, Alan. AU - Tunick, Paul A.. AU - Kronzon, Itzhak. PY - 2005/4/1. Y1 - 2005/4/1. N2 - Twenty-three patients who had septal wall motion abnormalities and who underwent angiography within 2 weeks were evaluated by myocardial perfusion echocardiography. Mean perfusion score (plateau video intensity times the wash-in rate) was lower in segments that were supplied by obstructed coronary arteries in real time (7.5 vs 22.6 dB/s, p ,0.005) and with end-systolic triggering (8.6 vs 20.9 dB/s, p ,0.001). Lower mean septal perfusion scores (,12 dB/s) were seen in 14 of 16 patients who had obstructive septal coronary artery disease, and normal mean septal perfusion scores were seen in 6 of 7 patients ...

Recent evidence suggests that higher restenosis rate is observed after coronary angioplasty of an infarct-related artery. Furthermore, angiographic restenosis seems associated with a deterioration of left ventricular function at follow-up. The aim of this study was to assess the acute results and angiographic restenosis following coronary artery stenting of infarct-related (Group 1) and non infarct-related coronary arteries (Group 2). We retrospectively analyzed the results of 381 consecutive patients treated with Palmaz-Schatz coronary stent implantation between May 1992 and January 1996. Stenting of the infarct-related artery was performed in 154 patients (Group 1), while 227 patients (Group 2) received stenting of the non infarct-related artery. Both groups had similar age, gender, clinical conditions and coronary angiographic pattern. There were no significant differences between groups, concerning type of stented coronary vessel (left anterior descending-LAD 52.4% vs non-LAD 47.6%, Group 1, ...

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Objectives Our aim was to compare the effectiveness between right radial approach (RRA) and left radial approach (LRA) by means of a randomized study in a large unselected patient population undergoing diagnostic coronary angiography. Methods Totally, 1,000 patients were randomized to undergo to RRA (n = 500) or LRA (n = 500). Procedure success was defined as coronary angiography completed with the initial radial artery approach without changing to another route. Performance of the procedure: Total procedural duration, the number of catheters and guidewires used were recorded. Safety of the procedure: The parameters collected for radiation exposure were dose area product (DAP) and fluoroscopy time. Results The percentage of success was not different between the two aproaches (LRA, 94.0%; RRA,93.8%; P = 0.96). The crossover rate to femoral was low, accounting for 38 cases (3.8%), without differences between RRA and LRA (20 and 18 cases, respectively, P > 0.05). An almost triple incidence of ...

Hazy filling defect on coronary angiography: insights from optical coherence tomography Other Refereed Contribution to Refereed Journals ...

TY - JOUR. T1 - Prognostic value of combined CT angiography and myocardial perfusion imaging versus invasive coronary angiography and nuclear stress perfusion imaging in the prediction of major adverse cardiovascular events. T2 - The CORE320 multicenter study. AU - CORE320 Investigators. AU - Chen, Marcus Y.. AU - Rochitte, Carlos E.. AU - Arbab-Zadeh, Armin. AU - Dewey, Marc. AU - George, Richard T.. AU - Miller, Julie M.. AU - Niinuma, Hiroyuki. AU - Yoshioka, Kunihiro. AU - Kitagawa, Kakuya. AU - Sakuma, Hajime. AU - Laham, Roger. AU - Vavere, Andrea L.. AU - Cerci, Rodrigo J.. AU - Mehra, Vishal C.. AU - Nomura, Cesar. AU - Kofoed, Klaus F.. AU - Jinzaki, Masahiro. AU - Kuribayashi, Sachio. AU - Scholte, Arthur J.. AU - Laule, Michael. AU - Tan, Swee Yaw. AU - Hoe, John. AU - Paul, Narinder. AU - Rybicki, Frank J.. AU - Brinker, Jeffrey A.. AU - Arai, Andrew E.. AU - Matheson, Matthew B.. AU - Cox, Christopher. AU - Clouse, Melvin E.. AU - Di Carli, Marcelo F.. AU - Lima, João A.C.. N1 - ...

TY - JOUR. T1 - Reimplantation of anomalous right coronary artery from left main coronary artery. T2 - A surgical option. AU - Karimi, Mohsen. AU - Murdison, Kenneth A. AU - Blackwood, Wesley. AU - Davis, Wesley. PY - 2010/4/1. Y1 - 2010/4/1. N2 - Anomalous right coronary artery (ARCA) from left sinus of Valsalva could present in several forms either being intramural or extramural, and most occurring with separate ostium from left coronary system. ARCA originating from the left main coronary artery (LMCA) is very rare and treatments proposed for this type of anomaly are pulmonary artery translocation or coronary artery bypass grafting (CABG) of the right coronary system. There has not been any report in the literature of successful reimplantation of ARCA from LMCA, to the best of our knowledge, as another surgical option for this anomaly. We are reporting a case of successful surgical reimplantation of an ARCA from LMCA.. AB - Anomalous right coronary artery (ARCA) from left sinus of Valsalva ...

TY - JOUR. T1 - Impact of the Extent of Coronary Artery Disease on Outcomes After Revascularization for Unprotected Left Main Coronary Artery Stenosis. AU - Kim, Young Hak. AU - Park, Duk Woo. AU - Kim, Won Jang. AU - Lee, Jong Young. AU - Yun, Sung Cheol. AU - Kang, Soo Jin. AU - Lee, Seung Whan. AU - Lee, Cheol Whan. AU - Hong, Myeong Ki. AU - Park, Seong Wook. AU - Park, Seung Jung. PY - 2010/6/8. Y1 - 2010/6/8. N2 - Objectives: This study was designed to examine the impact of the extent of coronary disease on long-term outcomes after coronary stenting or coronary artery bypass graft (CABG) surgery for unprotected left main coronary artery (ULMCA) stenosis. Background: The differential outcome of ULMCA revascularization according to the coronary involvement remains uncertain. Methods: From the MAIN-COMPARE (Revascularization for Unprotected Left Main Coronary Artery Stenosis: Comparison of Percutaneous Coronary Angioplasty versus Surgical Revascularization) registry, 2,240 patients with ULMCA ...

TY - JOUR. T1 - Determinants of fluoroscopy time for invasive coronary angiography and percutaneous coronary intervention. T2 - Insights from the NCDR®. AU - Fazel, Reza. AU - Curtis, Jeptha. AU - Wang, Yongfei. AU - Einstein, Andrew J.. AU - Smith-Bindman, Rebecca. AU - Tsai, Thomas T.. AU - Chen, Jersey. AU - Shah, Nilay D.. AU - Krumholz, Harlan M.. AU - Nallamothu, Brahmajee K.. N1 - Copyright: Copyright 2014 Elsevier B.V., All rights reserved.. PY - 2013/12/1. Y1 - 2013/12/1. N2 - Objectives Identifying the distributions and determinants of fluoroscopy time for invasive coronary angiography (ICA) and percutaneous coronary intervention (PCI). Background ICA and PCI are significant contributors to radiation exposure from medical imaging in the US. Fluoroscopy time is a potentially modifiable determinant of radiation exposure for these procedures, but has not been well characterized in contemporary practice. Methods We evaluated the distribution of fluoroscopy time in patients undergoing ICA ...

Spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndrome and sudden cardiac death with high predilection for premenopausal women. The overall incidence of SCAD in patients referred for coronary angiography has been reported to vary between 0.1% and 1%. In a series of 94 antemortem and postmortem cases the mean age for men was 46 years and the mean age for women was 39 years. In this series, the dissection of right coronary artery was more common in men while the left coronary artery system was most commonly affected in women. Although the precise etiology of SCAD remains unclear, several risk factors such as atherosclerosis, connective tissue disorder, peri-partum episode, and trauma have been postulated. Consequently, SCAD could result in a wide spectrum of presentations ranging from chest pain to extensive myocardial infarction. Notably, sudden cardiac death has been a common mode of clinical presentation in many previously reported cases. While the definitive diagnosis

Keywords: Anomaly, congenital anomalies, coronary artery nomalies, fistula PCI congenital anomalies, gender, PCI.. Abstract: Background: Although not well established; gender may play a role in the incidence, clinical manifestations, and atherosclerotic burden of Coronary Artery Anomalies (CAAS). Our aim is to investigate the impact of gender on coronary artery anomalies. Methods: All coronary angiograms performed at the University Heart Center Zurich, Switzerland, between January 2000 and December 2016 were investigated. Those of anomalous origin, course and termination (fistula) were included in the analysis with the exclusion of coronary artery aneurysms and myocardial bridges. Results: Out of the original 39577 angiographic studies that included 28550 males and 11026 females, Coronary Artery Anomalies (CAAS) were documented in 130 (0.32%) patients of whom 69.2% (n=90) and 30.8%(n=40) were males and females respectively. However, the overall prevalence of coronary anomalies amongst both ...

Looking for online definition of Coronary catheterization in the Medical Dictionary? Coronary catheterization explanation free. What is Coronary catheterization? Meaning of Coronary catheterization medical term. What does Coronary catheterization mean?

OBJECTIVES We sought to ascertain the utility of adenosine thallium-201 tomography for assessing graft stenoses late after coronary artery bypass graft surgery. BACKGROUND Although pharmacologic perfusion imaging has been increasingly used in the assessment of patients with coronary artery disease, the value of this stress modality for detecting coronary artery bypass graft stenosis late after surgery is unknown. METHODS We studied 109 patients who underwent both adenosine thallium-201 tomography and coronary angiography at 6.7 +/- 4.8 (mean +/- SD) years after coronary artery bypass graft surgery. Adenosine thallium-201 tomography was assessed quantitatively by computer-generated polar maps of the myocardial thallium-201 activity. RESULTS On coronary angiography, significant graft stenoses were present in 68 patients, 65 of whom had a corresponding perfusion defect as shown by thallium-201 tomography (sensitivity 96%). Significant stenoses were present in 107 (37.8%) of 283 grafts. The overall

ST-elevation myocardial infarction (STEMI) rarely occurs among patients 18 to 34 years old. Spontaneous coronary artery dissection (SCAD) is a rare cause of STEMI and is frequently described among patients in peripartum period. SCAD has a high mortality rate if not recognized and treated immediately. We present a case of SCAD presenting as STEMI in a 19-year-old nonpregnant patient. A 19-year-old female with chronic kidney disease, complained of sudden onset substernal chest pain. Physical examination showed a blood pressure of 140/90 mm Hg, HR of 112 bpm, with note of rales, pedal edema, and cold clammy extremities. Electrocardiogram showed ST-elevation in leads V3 to V6. Cardiac troponin was elevated and echocardiography revealed left ventricular segmental hypokinesia and depressed systolic function. Patient was diagnosed with acute anterolateral wall STEMI. Coronary angiogram revealed total occlusion of the mid-segment of the left anterior descending artery (LAD), while the rest of the ...

Is spontaneous coronary artery dissection (SCAD) related to vascular inflammation and epicardial fat? -insights from computed tomography coronary angiography

Diagnostic cardiac catheterization and coronary angiography are considered the gold standard in the assessment of the anatomy and physiology of the heart and its associated vasculature. In 1929, Forssmann demonstrated the feasibility of cardiac catheterization in humans when he passed a urological catheter from a vein in his arm to his right atrium and documented the catheters position in the heart by x-ray. In the 1940s, Cournand and Richards applied this technique to patients with cardiovascular disease to evaluate cardiac function. These three physicians were awarded the Nobel Prize in 1956. In 1958, Sones inadvertently performed the first selective coronary angiography when a catheter in the left ventricle slipped back across the aortic valve, engaged the right coronary artery, and power-injected 40 mL of contrast down the vessel. The resulting angiogram provided superb anatomic detail of the artery, and the patient suffered no adverse effects. Sones went on to develop selective coronary ...

The use of Coronary Artery Bypass Grafting (CABG) rather than Percutaneous Coronary Intervention (PCI) for the management of patients with triple vessel or left main coronary artery disease is associated with lower rates of major adverse cardiac or cerebrovascular events at 1 year. The conclusion is based on a trail (STNTAX trail) published in New England Journal of Medicine March 2009 edition.. The SYNTAX (Synergy between PCI with taxus and cardiac surgery) trail, conducted in United States and several countries in Europe, involved 1800 patients with previously untreated triple vessel disease or left main coronary artery disease. The patients were randomly assigned to undergo CABG or PCI and were monitored for the subsequent 12 month period for any major cardiac or cerebrovascular event. Death from any cause, stroke, myocardial infarction and repeat revascularization were considered as major adverse events. The research was sponsored by Boston Scientific, developer of the drug eluting taxus ...

Coronary artery aneurysm is an abnormal dilatation of part of the coronary artery. Acquired causes include atherosclerosis, Kawasaki disease and coronary catheterization. It can also be congenital. It is often found coincidentally on coronary angiography. Generally, it has a good prognosis. In Kawasakis disease, untreated, there is a 1-2% death rate, from cardiac causes. Nichols L, Lagana S, Parwani A (May 2008). Coronary artery aneurysm: a review and hypothesis regarding etiology. Arch. Pathol. Lab. Med. 132 (5): 823-8. doi:10.1043/1543-2165(2008)132[823:CAAARA]2.0.CO;2. PMID 18466032. Fukazawa R, Ikegam E, Watanabe M, et al. (May 2007). Coronary artery aneurysm induced by Kawasaki disease in children show features typical senescence. Circ. J. 71 (5): 709-15. doi:10.1253/circj.71.709. PMID 17456996. Archived from the original (- Scholar search) on 2012-12-19. Seabra-Gomes R, Somerville J, Ross DN, Emanuel R, Parker DJ, Wong M (April 1974). Congenital coronary artery aneurysms. Br Heart ...

Spontaneous coronary artery dissection (SCAD) is a rare myocardial ischemic disease that threatens patients life. Various risk factors are associated with SCAD, such as smoking, severe hypertension and psychological reasons.

Long term objective:Discover molecular and cellular mechanisms of SCAD and develop biomarkers to enable prediction and prevention.. The purpose of the research is to identify mutations (defects in the genetic blueprint) that cause tears in blood vessels that supply the heart. Some mutations may be inherited (passed on) from a parent without an apparent blood vessel problem while others may develop for the first time in the affected person. The study includes individuals diagnosed with spontaneous coronary artery dissection and their biological parents.. Adults with SCAD will be identified both retrospectively and prospectively.Confirmation of the diagnosis by review of coronary angiography will be required before proceeding with the informed consent process and blood or saliva sample procurement. ...

Background and Purpose: Coronary artery disease in moyamoya disease (MMD) have been described sporadically in several case reports. The purpose of this study is to determine the prevalence and characteristics of coronary artery disease in patients with MMD.. Methods: From August 1991 to December 2012, 446 patients diagnosed with adult MMD at our hospital. Baseline characteristics and prevalence of coronary artery disease were reviewed based on medical records and laboratory findings. The findings of conventional coronary angiography and/or coronary computed tomography were also reviewed for the presence and appearance of coronary artery lesion.. Results: - Of 446 patients with adult MMD, 21 patients were found to have coronary artery disease. Ten patients were treated with coronary artery bypass graft (n=4) or percutaneous coronary intervention (n=6) for unstable angina or myocardial infarction. Eleven were treated with medication for stable angina (n=6) and variant angina with mild degree of ...

OBJECTIVE: To compare radiation doses delivered at prospectively ECG-triggered sequential- (SEQ), retrospectively ECG-gated spiral- (RETRO) and prospectively ECG-triggered high-pitch spiral- (HP) computed tomography coronary angiography (CTCA) protocols, as well as catheter coronary angiography (CCA) using an anthropomorphic phantom. MATERIALS AND METHODS: An anthropomorphic Alderson phantom equipped with 50 thermoluminescent dosimeters (TLDs) was scanned using different CTCA protocols and an uncomplicated diagnostic CCA examination was simulated. Absorbed doses were experimentally determined and effective doses calculated using the dose-length product (DLP) for CTCA and the dose-area product (DAP) for CCA, as well as according to International Commission on Radiation Protection (ICRP) publications 60 and 103. RESULTS: Effective organ doses were significantly lower for HP protocols (100kV: 0.17±0.26mSv; 120kV: 0.26±0.39mSv) compared to SEQ protocols (100kV: 0.50±0.79mSv; 120kV: 0.90±1.41mSv; ...

Coronary artery disease is a condition in which the coronary arteries are narrowed by deposits called plaques.. The coronary arteries originate from the aorta and supply blood and oxygen to your heart muscle allowing it pump blood to the body. Normal coronary arteries allow blood to flow freely. However, these arteries can become narrowed by inflammatory fatty deposits called plaques. This disease process is called atherosclerosis. Atherosclerosis that occurs in the coronary arteries is called coronary artery disease.. These plaques build up over time and can decrease the amount of oxygen reaching your heart. Mild coronary artery disease may develop over decades without any symptoms. More severe coronary artery disease can cause chest pain, called angina, and shortness of breath.. If a plaque suddenly ruptures, a blood clot can form and block the hearts blood supply. This is called a heart attack and it can cause permanent damage to the heart. Over time, severe coronary artery disease can also ...

Study Start Date: April 2014. Spontaneous Coronary Artery Dissection (SCAD) is an unpredictable event in which patients typically first present with a sudden, unexpected heart attack. The condition can affect all age groups and is recognised as a cause of heart attacks in young adults. Although both men and women can be affected by SCAD, the condition is more common in women, particularly during or shortly after pregnancy.. SCAD results from an acute bleed into the vessel wall of a coronary artery creating a false lumen (a lumen is the term for the inside of a blood vessel, the tube down which the blood is supposed to flow). This accumulation of blood compresses the true lumen, restricting or preventing blood flow to the heart muscle. Little is currently known about the underlying causes of SCAD and its long-term outcomes, or indeed, how best to treat it. (Picture below shows angiographs of vessel before (A) and after (B) stenting.). ...

DISCUSSION AND CONCLUSION: C-CTA is an effective method in detecting coronary artery diseases, variations and anomalies. There are studies indicating that c-CTA is superior to catheter angiography in the diagnosis of coronary artery anomalies. Coronary artery anomalies are the uncommon category of cardiac diseases. Their incidence in the community is 1-2%. Our study supports that c-CTA is an imaging method that is used in the diagnosis of coronary artery anomalies and variations and provides detailed information ...

THE ROLE OFMULTIDETECTOR COMPUTED TOMOGRAPHY CORONARY ANGIOGRAPHY IN THE FOLLOW UP OF CORONARY ARTERY FISTULA AFTER CLOSURE BY PERCUTANEOUS INTERVENTION ...

U.S., Feb. 9 -- ClinicalTrials.gov registry received information related to the study (NCT03042845) titled Randomized Comparison of JUDkins vs tiGEr Catheter in Coronary Angiography Via the Right Radial Artery: the JUDGE Study on Feb. 1. Brief Summary: The investigators aim to assess safety and efficiency of Tiger II (5Fr; Terumo Interventional Systems, Somerset, New Jersey) vs Judkins (5Fr; 3.5L/4R, Medtronic Co) catheters, in coronary angiography via the right transradial route. This is a prospective, randomized, study of parallel design. Consecutive patients with acute coronary syndrome (ACS), eligible for non-urgent coronary angiography, are randomized after successful cannulation of right radial artery and informed consent to either Tigger II or Judkins 3.5L/4R catheters. Study Start Date: Study Type: Interventional Condition: Coronary Artery Disease Intervention: Device: Tiger cardiac catheter Tiger cardiac catheter Device: Judkins 3.5L/4R cardiac catheters Judkins 3.5L/4R cardiac ...

Title:Intracoronary Injection of Glycoprotein IIb/IIIa, Abciximab, as Adjuvant Therapy in Primary Coronary Intervention. VOLUME: 11 ISSUE: 2. Author(s):Andrea Rognoni, Alessadro Lupi, Chiara Cavallino, Roberta Rosso, Alessia Veia, Sara Bacchini and Angelo Sante Bongo. Affiliation:Coronary Care Unit and Catheterization Laboratory, Hospital Maggiore della Carita, Corso Mazzini 18, 28100 Novara, Italy.. Keywords:STEMI, Acute coronary syndrome, adjuvant therapy, bleeding, GP IIb/IIIa inhibitors, in - stent restenosis, no - reflow phenomenon, percutaneous coronary intervention, platelet, thrombosis.. Abstract:Acute coronary syndromes and, in paticular, ST - segment elevation myocardial infarction are the principle causes or mortality and morbidity in the industrialized countries. The manadgement of acute myocadial infarction is much debated in the literature; primary percutaneous coronary intervention is the treatment of choice. In the recent years there has been an increasing interest in the ...

An anomalous coronary artery (ACA) is a coronary artery that has an abnormality or malformation. The malformation is congenital (present at birth) and is most often related to the origin or location of the coronary artery. However, there may be other defective areas in the coronary artery. Likewise, it may affect the overall size and shape of the affected coronary artery or arteries. ACA may also occur along with other congenital heart defects.. This condition may also be called congenital coronary artery anomaly (CAA).. Although they are present at birth, ACAs are often not diagnosed until late adolescence or adulthood, because of the lack of symptoms or because symptoms may not be recognized as being caused by ACA. Teens or adults with unknown ACA may have an initial episode of chest pain, heart failure, or even sudden cardiac death before the condition is recognized.. ...

In this study, we investigate plaques located at the left coronary bifurcation. We focus on the effect that the resulting changes in wall shear stress (WSS) and wall pressure stress gradient (WPSG) have on atherosclerotic progress in coronary artery disease. Coronary plaques were simulated and placed at the left main stem and the left anterior descending to produce ,50% narrowing of the coronary lumen. Computational fluid dynamics analysis was carried out, simulating realistic physiological conditions that show the in vivo cardiac haemodynamic. WSS and WPSG in the left coronary artery were calculated and compared in the left coronary models, with and without the presence of plaques during cardiac cycles. Our results showed that WSS decreased while WPSG was increased in coronary side branches due to the presence of plaques. There is a direct correlation between coronary plaques and subsequent WSS and WPSG variations based on the bifurcation plaques simulated in the realistic coronary ...

article{af90d0aa-e201-4e8a-80ec-fd031ac8fe29, abstract = {BACKGROUND: The study aimed to investigate patient and spouse perception of cognitive functioning 1 to 2 years after coronary artery bypass grafting. METHODS: Seventy-six married patients who had undergone coronary artery bypass grafting were selected and sex- and age-matched with 75 concurrent married patients who had undergone percutaneous transluminal coronary angioplasty. Couples received a letter of explanation and then completed telephone interviews. Forty-seven questions assessed memory, concentration, general health, social functioning, and emotional state. Response choices were: improved, unchanged, or deteriorated function after coronary artery bypass grafting/percutaneous transluminal coronary angioplasty. RESULTS: Patients who had undergone coronary artery bypass grafting did not differ in subjective ratings on any measure from patients who had undergone percutaneous transluminal coronary angioplasty. There were no differences ...

Fractional flow reserve (FFR) is a reliable tool for the functional assessment of coronary stenoses. FFR computed tomography (CT) derived (FFRCT) has shown to be accurate, but its clinical usefulness in patients with complex coronary artery disease remains to be investigated. The present study sought to determine the impact of FFRCT on heart teams treatment decision-making and selection of vessels for revascularization in patients with 3-vessel coronary artery disease. Methods: The trial was an international, multicenter study randomizing 2 heart teams to make a treatment decision between percutaneous coronary interventions and coronary artery bypass grafting using either coronary computed tomography angiography or conventional angiography. The heart teams received the FFRCT and had to make a treatment decision and planning integrating the functional component of the stenoses. Each heart team calculated the anatomic SYNTAX score, the noninvasive functional SYNTAX score and subsequently ...

Acute Coronary Syndrome in a Patient with a Single Coronary Artery Arising from the Right Sinus of Valsalva: A Case Report Tripodi, Alberto; DellAmore, Andrea; Aquino, Tommaso; Pagliaro, Marco; Fedeli, Corrado; Magnano, Diego; Calvi, Simone; Zussa, Claudio; Lamarra, Mauro; DellAmore, Andrea // Heart, Lung & Circulation;Oct2008, Vol. 17 Issue 5, p421 Coronary anomalies can involve origin or distribution of the artery. Most of these anomalies are not clinically important. A single coronary artery arising from the right coronary sinus of Valsalva is an extremely rare anatomic anomaly. Usually coronary artery malformation is associated with... ...

TY - JOUR. T1 - Increased exercise thallium-201 lung uptake. T2 - A noninvasive prognostic index in two-vessel coronary artery disease. AU - Miller, D. D.. AU - Kaul, S.. AU - Strauss, H. W.. AU - Newell, J. B.. AU - Okada, R. D.. AU - Boucher, C. A.. N1 - Copyright: Copyright 2004 Elsevier B.V., All rights reserved.. PY - 1988. Y1 - 1988. N2 - To determine the physiologic impact of two-vessel coronary artery disease and its effect on prognosis, a series of clinical, angiographic, exercise and quantitative thallium-201 (Tl-201) imaging parameters were analyzed in 85 consecutive two-vessel coronary artery disease patients followed for 52 ± 27 months after coronary angiography and Tl-201 scintigraphy. End points were cardiac death (n = 3), myocardial infarction (n = 6) and coronary bypass graft surgery more than three months after testing (n = 16). Using Cox Hazards survival analysis, early cardiac events were not predicted by: myocardial infarction or anginal history; resting left ventricular ...

TY - JOUR. T1 - Segmental coronary artery disease. T2 - Detection by rotating slant-hole collimator tomography and planar thallium 201 myocardial scintigraphy. AU - Starling, M. R.. AU - Dehmer, G. J.. AU - Lancaster, J. L.. PY - 1985/1/1. Y1 - 1985/1/1. N2 - Normal quantitative circumferential profile limits were established for a 30° bilateral rotating slant-hole (RSH) collimator tomographic system. This systems value in detecting segmental coronary artery disease was assessed in a study evaluating 196 patients by thallium 201 myocardial scintigraphy and coronary arteriography. Profile curves were calculated from images of 20 healthy patients and used to identify significant coronary artery disease (≥ 70% diameter narrowing) in the left anterior descending (LAD), the right, and the left circumflex (LCx) coronary arteries. In a group of 86 patients, an abnormality on the apical or middle plane optimally identified segmental coronary artery disease. When such abnormalities were prospectively ...

Background: With the improved lifestyle of people, the incidence of coronary artery disease is gradually increasing. Approximately 15% - 20% of patients undergoing diagnostic catheterization had one or more chronically occluded coronary arteries. Method: The patients who were diagnosed with chronic total occlusion (CTO) in our hospital within one year period have been included. They were initially divided into two groups based on angiographic reports: single vessel disease (SVD) and non-single vessel disease (non-SVD) group, then into optimal medical therapy (OMT) group, percutaneous coronary intervention (PCI) group and coronary artery bypass graft (CABG) group. Finally, PCI group is further divided into PCI of CTO lesion (CTO PCI group) and PCI of non-CTO lesion (non-CTO PCI group). Results: A total of 261 patients were enrolled as CTO patients, mean age was 62.83 years, 70.1% were male patients. The incidence rate of common risk factors was hypertension (64.4%), followed by smoking (48.3%), diabetes

Coronary artery disease is among the most common causes of disability and death. Often, by the time symptoms occur, the process may already be far advanced. Frequently,t he first symptom of coronary artery disease is heart attack and sudden death. Dangerous coronary artery disease may be present in individuals that are totally asymptomatic. A recent study showed that a family history of early-onset coronary artery disease (CAD) is associated with significant amounts of plaque in the coronary arteries apparently healthy patients.. Researchers demonstrated a significant amount of plaque present (coronary plaque burden) in apparently healthy middle-aged close relatives of individuals with early-onset of coronary artery disease. This study underscores the fact that asymptomatic patients may benefit from early cardiac screening and that is especially true for individuals with a family history of early-onset CAD may benefit from screening for subclinical atherosclerosis.. The Cardiac portion of the ...

Chest pain following successful percutaneous coronary interventions is a common problem. Although the development of chest pain after coronary interventions may be of benign character, it is disturbing to patients, relatives and hospital staff. Such pain may be indicative of acute coronary artery closure, coronary artery spasm or myocardial infarction, but may also simply reflect local coronary artery trauma. The distinction between these causes of chest pain is crucial in selecting optimal care.Management of these patients may involve repeat coronary angiography and additional intervention. Commonly, repeat coronary angiography following percutaneous transluminal coronary angioplasty (PTCA) in patients with chest pain demonstrates widely patent lesion sites suggesting that the pain was due to coronary artery spasm, coronary arterial wall stretching or was of non-cardiac origin. ...

The effect of a new coronary vasodilator (Persantin), which produces a marked increase in coronary blood flow (up to 159 per cent in normal animals) without increasing cardiac contractility or cardiac work, has been studied in the experimental animal. This is associated with a marked decrease in coronary resistance. There is an increase in the coronary venous oxygen content and a decrease in the coronary A-V oxygen difference; the cardiac output is only slightly affected. Increase in the coronary blood flow has also been observed in dogs in which coronary in sufficiency has been produced by coronary ligation and by narrowing of the lumen of the coronary artery by the application of casein rings. This was accompanied by no significant increase in cardiac work.. ...

Title: Surgical or Interventional Revascularization in Diabetic Patients with Coronary Artery Disease?. VOLUME: 6 ISSUE: 6. Author(s):E. Apostolakis, I. Koniari, D. Velissaris and Efstratios N. Koletsis. Affiliation:Department of Cardiothoracic Surgery, Department of Anaesthesiology and ICU, University of Patras, Patras, Greece.. Keywords:Coronary artery disease, Diabetes mellitus, Coronary artery bypass grafting, Percutaneous transluminal coronary angioplasty, Myocardial infarction, Revascularization, percutaneous transluminal, Surgical revascularization, prothrombotic situation, lipoproteins, manifestations, triglyceride-rich, triggering mechanisms, Plaque-angiogenesis, catabolism, CABG surgery, Abciximab, ischemia, SPECT, AWESOME, worsening symptoms, BASKET-LATE, MACE, perioperatively. Abstract: The combination of diabetes mellitus and coronary artery disease (CAD) constitutes an aggressive disease characterized biologically by chronic inflammatory, proliferative and pro-thrombotic situation. ...

TY - JOUR. T1 - Performance of computed tomography-derived fractional flow reserve using reduced-order modelling and static computed tomography stress myocardial perfusion imaging for detection of haemodynamically significant coronary stenosis. AU - Ihdayhid, Abdul Rahman. AU - Sakaguchi, Takuya. AU - Linde, Jesper J.. AU - Sørgaard, Mathias H.. AU - Kofoed, Klaus F.. AU - Fujisawa, Yasuko. AU - Hislop-Jambrich, Jacqui. AU - Nerlekar, Nitesh. AU - Cameron, James D.. AU - Munnur, Ravi K.. AU - Crosset, Marcus. AU - Wong, Dennis T.L.. AU - Seneviratne, Sujith K.. AU - Ko, Brian S.. PY - 2018/11/1. Y1 - 2018/11/1. N2 - Aims: To compare the diagnostic performance of a reduced-order computed tomography-derived fractional flow reserve (CT-FFR) technique derived from luminal deformation and static CT stress myocardial perfusion (CTP).Methods and results: Forty-six patients (84 vessels) with suspected coronary artery disease from a single institution planned for elective coronary angiography ...

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