Gene therapy for hematological disorders relies in the hereditary change of Compact disc34+ cells, a heterogeneous cell population containing on the subject of 0. cells suffered gene observing for a extended period of period with a 6.7-fold higher recovery of barcodes compared to transduced control cells. Furthermore, Compact disc133-LV-transduced cells had been able of repopulating supplementary recipients. Finally, we present that this concentrating on technique can end up being utilized for transfer of a healing gene into Compact disc34+ cells attained from sufferers struggling of X-linked chronic granulomatous disease. In bottom line, immediate gene transfer into Compact disc133+ cells enables for suffered long lasting engraftment of gene adjusted cells. Launch A series of stage 1/2 scientific studies have got supplied convincing proof that modification of hereditary flaws by gene transfer Hbb-bh1 into hematopoietic Compact disc34+ cells is normally an choice healing strategy to allogeneic ...
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Cadmium (Compact disc) is a popular soil pollutant; hence, the root molecular handles of plant Compact disc tolerance are of significant curiosity. Cys-rich metallothionein protein are the primary chelators of Compact BRL-49653 disc and various other large metals in pets (including human beings) (Imura et al., 1989; Clemens, 2001). Bakers fungus contains an individual metallothionein gene, (copper level of resistance associated proteins), which stocks lots of the simple features of the pet metallothionein genes (Butt and Ecker, 1987). Metallothioneins also are likely involved in rock chelation and rock homeostasis in plant life (Zhou BRL-49653 and Goldsbrough, 1994). Furthermore to metallothioneins, plant life synthesize the glutathione-derived phytochelatins, which bind Compact disc and thereby decrease the relationship of its free of charge ionic type BRL-49653 with essential cytosolic proteins (Clemens et al., 1999; Ha et al., 1999). Extrusion of BRL-49653 Compact disc with the ABC ...
A Geotrichum-like fungus isolated from a biodeteriorated compact disc (CD) was able to degrade in vitro the components of different CD types. The fungal hyphae inside the CD fragments grew through the aluminium layer and produced the solubilization of this metal. Furthermore, examination of CDs by scanning electron microscopy showed that the fungus was able to destroy the pits and lands structures grooved in the polycarbonate layer, confirming degradation of this aromatic polymer. The fungus secretes aryl-alcohol oxidase and Mn2+-oxidizing peroxidase, two kinds of oxidoreductases characteristic of ligninolytic basidiomycetes. Analysis of the ITS region of ribosomal DNA, as well as the morphological characteristics, the lack of sexual forms and the profile of enzymes secreted in liquid medium identified the fungus as a Geotrichum-like anamorph of Bjerkandera adusta (Willd.) P. ...
IL-10-producing B (Breg) cells regulate various immune responses. way (Fig. 4A and ?and4B).4B). CCR7 Up coming we determined if the improvement of Compact disc40hiCD5+ B cells was reliant BMS-707035 on IL-10 in mice. The splenic inhabitants of Compact disc40hiCD5+ Breg cells was significantly elevated in LPS-stimulated WT (IL-10+/+) mice however not in IL-10?/? mice (Fig. 4C). These outcomes strongly claim that the forming of Compact disc40hiCD5+ Breg cells was governed by IL-10 in mice. Fig. 4. The forming of LPS-induced Compact disc40hiCD5+ B cells would depend on endogenous IL-10 creation in mice. (A) Consultant images (B) regularity and variety of IL-10-making splenic B cells in mice treated with LPS (1 mg/kg i.v.) for 0 to 3 times. For intracellular … Debate Breg cells have already been acknowledged to possess anti-inflammatory activity in a variety of immune responses. The phenotypic characterization of Breg cells remains incomplete Nevertheless. The purpose of our research was to look ...
Rat Compact disc39 a membrane-bound ectonucleoside triphosphate diphosphohydrolase that hydrolyzes extracellular nucleoside tri- and diphosphates is anchored towards the membrane by two transmembrane domains at both ends of the molecule. transmembrane domain name indicates that there is contact between particular faces of the transmembrane domains. strains DH5α (strain YMR4 ([24]. Standard rich (YPD) and complete minimal uracil drop-out (DO-U) media were used for yeast [25]. The composition of the DO-U medium with 0.3 mM ATP was 0.9 g of DO-U powder 5 g of IKBKB antibody (NH4)2SO4 1.02 g of MgSO4-7H2O 0.1675 g of CaCl2 0.1 g of NaCl 0.55 g of KCl 12.1 g of Tris base and 0.165 g of ATP disodium salt (Sigma Aldrich) per liter of water; the pH was titrated to 7.2 with HCl. Glucose (2%) vitamins and trace elements (DIFCO SB-262470 manual) were added after sterilization. Creation of an acid phosphatase-negative strain of and genes respectively to create an acid phosphatase-negative (APN) YMR4 yeast ...
Background A T cell costimulatory molecule with dipeptidyl peptidase IV (DPPIV) activity in its extracellular area, Compact disc26 is a multifunctional molecule connected with various protein such as for example adenosine deaminase, caveolin-1, CXCR4, collagen, and fibronectin, while using a significant function in the regulation of inflammatory tumor and replies biology. molecule in the formalin-fixed paraffin-embedded tissue is critical. SOLUTIONS TO develop book anti-CD26 mAbs with the capacity of binding towards the denatured Compact disc26, we immunized mice with Compact disc26 proteins denatured in urea buffer. Following the fusion of myeloma and splenocytes cells, the mAbs had been screened for particular reactivity with individual Compact disc26 by stream cytometry, enzyme-linked immunosorbent assay, and immunohistochemistry. The binding competitiveness of novel anti-CD26 mAbs using the humanized anti-CD26 mAb YS110 was also analyzed. Results Weve been successful in developing book ...
Purpose To assess aldehyde dehydrogenase (ALDH) reflection in adult individual and murine submandibular gland (SMG) control cells and to determine the impact of ALDH3 account activation in SMG control cell enrichment. a story ALDH3 activator (Alda-89) or with automobile implemented by quantification of c-Kit+/Compact disc90+ SMG control cells and BrdUrd+ salispheres. Outcomes Even more than 99% of Compact disc34+ huSMG control cells tarnished positive for c-Kit, Compact disc90 and 70% colocalized with Compact disc44, Nestin. Likewise, 73.8% c-Kit+ mSMG control cells colocalized with Sca-1, whereas 80.7% with CD90. Functionally, these cells produced BrdUrd+ salispheres, which differentiated into acinar- and ductal-like buildings when cultured in 3D collagen. Both adult individual and murine SMG control cells demonstrated higher reflection of ALDH3 than in their nonCstem cells and 84% of these cells possess measurable ALDH1 activity. Alda-89 infusion in adult rodents considerably elevated ...
Bispecific antibodies (bsAbs) participating T cells are rising as a probable immunotherapeutic tool for the treatment of hematologic malignancies. co-stimulus buy AescinIIB via the Compact disc137-Compact disc137 ligand axis through Compact disc137L reflection on MSCs. This research demonstrates that MSCs possess the potential to end up being utilized buy AescinIIB as mobile creation devices for bsAb-based growth immunotherapy in the potential. Launch T-cell getting bispecific antibodies (bsAbs) are a appealing device for cancers treatment. This course of antibodies creates a transient synapse between Testosterone levels cells and cancers cells by presenting to a surface area antigen on cancers cells with one limb and concurrently enrolling Testosterone levels cells via the Compact disc3 domains, which is normally the indication sending part of the T-cell receptor complicated.1 The polarization of the T-cell complicated network marketing leads to an activation of bsAb buy AescinIIB recruited T ...
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NKG2D can be an activating receptor expressed on the top of defense cells including subsets of T lymphocytes. and exactly how these molecules influence autoimmune pathological procedures. Several studies have got recommended that NKG2D and its own ligands are likely involved in the pathobiology of MS. Weve previously proven that multiple NKG2DL are detectable on the proteins level on individual oligodendrocytes in principal civilizations (16). We confirmed that disruption from the NKG2D-NKG2DL relationship NIC3 inhibits eliminating of individual oligodendrocytes mediated by turned on human immune system effectors including Compact disc8 T lymphocytes (16). We discovered oligodendrocytes NIC3 expressing MICA/B in post-mortem MS tissue and Compact disc8 T lymphocytes near these NIC3 MICA/B-expressing cells (16). Notably, Co-workers and Ruck demonstrated that Compact disc4 T lymphocytes having NKG2D are enriched in the bloodstream, cerebrospinal liquid and post-mortem human brain lesions of MS ...
A number of immune-based therapies continues to be developed to be able to boost or induce protective Compact disc8+ T cell responses to be able to control HIV replication. [10]. Sadly, these fresh vaccines and therapies usually do not deliver the expected success yet. For example, Autran et al. reported considerably elevated viral lots in chronically contaminated patients set alongside the placebo group after discontinuation of therapy pursuing immunization with vCP1452, the HIV-recombinant canarypox vaccine (ALVAC-HIV) [11]. Incredibly, individuals receiving more dosages from the vaccine rapidly required treatment resumption more. Analysis of the results immensely important how the vaccine didnt elicit protecting HIV-specific Compact disc8+ T cell reactions [12]. Moreover, primarily induction of triggered Compact disc4+ T cell reactions was proven in vaccines, which increased target cell availability and rendered patients even more vunerable to Volasertib distributor disease progression ...
possesses unique cell-surface lipids which have been implicated in virulence. diacyl sulfolipid SL1278, a biosynthetic precursor of SL-1, is normally a well noted energetic metabolite (find Fig. 1). SL1278 was discovered to bind towards the MHC-like lipid receptor Compact disc1b also to stimulate the cytokines IFN- and IL-2 in Compact disc8+ T-cells from donors positive for the tuberculin buy 79307-93-0 epidermis test (18). Following work using artificial analogs of SL1278 demonstrated that the power of SL1278 to elicit a Compact disc1-limited T-cell response would depend on the space from the fatty acidity buy 79307-93-0 acyl stores, aswell buy 79307-93-0 as the existence and amount of methyl-branched substituents for the acyl stores (19). Elucidating the biosynthetic pathway of SL-1 can be a key element in focusing on how regulates SL-1 and its own precursors like a potential system for host immune system modulation. Lots of the preliminary measures in SL-1 biosynthesis have already been ...
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A prototype CFSM will be further developed to facilitate single-molecule manipulation. A sealed gasket encloses the sample chamber, which will be mounted on a spinning compact disk (see figure). A ds-DNA library, containing important transcription initiation and termination sequences, will be spotted on the lower surface of the sample chamber using DNA microarray technology. Each ds-DNA, prepared with biotin at its distal end, will bind a strepavidin-coated fluorescent microsphere. The centrifugal force will push (when viewed in a rotating frame of reference) these microspheres radially and so cause the attached ds-DNA to stretch. The laser on a modified compact disk player will be used to track the bead displacement. The centrifugal force on each microsphere can be calculated based on their size, density and radial velocity. The centrifugal force plotted against microsphere displacement will provide information about the physical properties (persistence length, overstretching transition, etc) ...
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Marxism has been adopted by a large number of academics and other scholars working in various disciplines. The theoretical development of Marxist archaeology was first developed in the Soviet Union in 1929, when a young archaeologist named Vladislav I. Ravdonikas (1894-1976) published a report entitled For a Soviet history of material culture. Within this work, the very discipline of archaeology as it then stood was criticised as being inherently bourgeois, therefore anti-socialist and so, as a part of the academic reforms instituted in the Soviet Union under the administration of Premier Joseph Stalin, a great emphasis was placed on the adoption of Marxist archaeology throughout the country.[35] These theoretical developments were subsequently adopted by archaeologists working in capitalist states outside of the Leninist bloc, most notably by the Australian academic V. Gordon Childe (1892-1957), who used Marxist theory in his understandings of the development of human society.[36] Marxist ...
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The role of the right hemisphere in recovery of language function after left hemisphere stroke remains unclear. This prospective study aimed to determine the relationship between bilateral hemispheric changes and severity of aphasia in patients with chronic left hemisphere stroke. Twenty-three patients with left hemisphere stroke with aphasia and 10 healthy control patients underwent high-resolution T1-weighted and diffusion tensor imaging. Patients with aphasia were assessed using the Korean version of the Western Aphasia Battery, and severity of aphasia was quantified in terms of aphasia quotient; patients were classified into two groups - the mild-to-moderate and severe groups - on the basis of severity of aphasia ...
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This Study Guide is designed to enhance your understanding of Results Now: How We Can Achieve Unprecedented, an ASCD book written by Mike Schmoker and published in July 2006. It will help you make connections between the text and the school or school district in which you work. The study guide can be used after you have read the entire book or as you finish each chapter. Most of the questions contained in this study guide are ones you can think about on your own. But you might also consider pairing with another colleague or forming a group of people who have read (or are reading) Results Now.. ...
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Supplementary MaterialsSupplementary_Components C Supplemental material for Effects of cladribine tablets on lymphocyte subsets in individuals with multiple sclerosis: an extended analysis of surface markers Supplementary_Materials. and reconstitution in ORACLE-MS, CLARITY, and CLARITY Extension during the 1st yr of treatment (i.e. the first course of CT1.75) in individuals randomized to CT3.5. Methods: Lymphocyte subtypes were analyzed using multiparameter circulation cytometry. Changes in cell counts and relative proportions of lymphocytes were evaluated at weeks 5, 13, 24, and 48. Results: Across studies, consistent and similar selective kinetics of immune cell populations occurred following a 1st treatment yr with CT. A rapid reduction in CD16+/CD56+ cells (week 5 nadir), a more marked reduction in Compact disc19+ B KPT-6566 cells (week 13 nadir), and a less-pronounced influence on Compact disc4+ (week 13 nadir) and Compact disc8+ T Srebf1 cells (week 24 nadir) was proven. There KPT-6566 is ...
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The dark, moody, and mystical fantasy begun in Thorn Jack, the first novel in the Night and Nothing series, continues in this bewitching follow up--an intriguing blend of Twilight, Buffy the Vampire Slayer, Alice in Wonderland, and A Midsummer Nights Dream--in which Finn Sullivan discovers that her town, Fair Hollow, borders a dangerous otherworld..... Serafina Sullivan and her father left San Francisco to escape the painful memory of her older sister Lily Roses suicide. But soon after she arrived in bohemian Fair Hollow, New York, Finn discovered a terrifying secret connected to Lily Rose. The placid surface of this picture-perfect town concealed an eerie supernatural world--and at its center, the wealthy, beautiful, and terrifying Fata family.. Though the striking and mysterious Jack Fata tried to push Finn away to protect her, their attraction was too powerful to resist. To save him, Finn--a girl named for the angels and a brave Irish prince--banished a cabal of malevolent enemies to ...
This list contains acronyms, initialisms, and pseudo-blends that begin with the letter H. For the purposes of this list: acronym = an abbreviation pronounced as if it were a word, e.g., SARS = severe acute respiratory syndrome, pronounced to rhyme with cars initialism = an abbreviation pronounced wholly or partly using the names of its constituent letters, e.g., CD = compact disc, pronounced cee dee pseudo-blend = an abbreviation whose extra or omitted letters mean that it cannot stand as a true acronym, initialism, or portmanteau (a word formed by combining two or more words). (a) = acronym, e.g.: SARS - (a) Severe acute respiratory syndrome (i) = initialism, e.g.: CD - (i) Compact disc (p) = pseudo-blend, e.g.: UNIFEM - (p) United Nations Development Fund for Women (s) = symbol (none of the above, representing and pronounced as something else; for example: MHz - Megahertz) (Main list of acronyms) Top H0-9 HA HB HC HD HE HF HG HH HI HJ HK HL HM HN HO HP HQ HR HS HT HU HV HW HX HY HZ h - (s) ...
Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells--taken without her knowledge--became one of the most important tools in medicine. The first immortal human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, theyd weigh more than 50 million metric tons--as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bombs effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions. Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave. Now Rebecca Skloot takes us on an extraordinary journey, from the colored ward of Johns Hopkins Hospital in the 1950s to stark white ...
The individual T-cell leukemia virus type 1 (HTLV-1) Tax protein hijacks the host ubiquitin machinery to activate IB kinases (IKKs) and NF-B and promote cell survival; nevertheless, the essential ubiquitinated elements downstream of Taxes included in cell alteration are unidentified. of HTLV-1 changed cells and the immortalization of principal Testosterone levels cells by HTLV-1. As a result, T63-connected polyubiquitination represents a story regulatory system managing MCL-1 balance that provides been usurped by a virus-like oncogene to precipitate cell success and alteration. Writer Overview HTLV-1 infections is certainly etiologically connected to the advancement of the neuroinflammatory disorder HTLV-1 linked myelopathy/exotic spastic paraparesis (Pig/TSP) and adult T-cell leukemia (ATL), an intense Compact disc4+Compact disc25+ malignancy. The HTLV-1 regulatory proteins Taxes constitutively activates the IB kinases (IKKs) and NF-B to promote cell success, transformation and proliferation. ...
It was just another after-work happy-hour bar downtown, where business professionals unwound with a few drinks, complained about the boss, maybe hooked up with someone for the night. Until something went terribly wrong. At first it was just a friction in the air. The noise intensified. The crowd seemed oppressive. Some sharp words were exchanged, some pushing and shoving. Then the madness descended. And after twelve minutes of chaos and violence, eighty people lay dead. Eve Dallas is trying to sort out the inexplicable events. Surviving witnesses talk about seeing things -- monsters and swarms of bees. They describe sudden, overwhelming feelings of fear and rage and paranoia. When forensics makes its report, the mass delusions make more sense: it appears the bar patrons were exposed to a cocktail of chemicals and illegal drugs that could drive people into temporary insanity -- if not kill them outright. But that doesnt explain who would unleash such horror -- or why. Eves husband, Roarke, ...
The use of complementary and alternative medicine (CAM) is increasing. The most common reported reason for CAM use is dissatisfaction with conventional healthcare. Several studies have reported factors influencing CAM usage and beliefs in the general public but the beliefs of healthcare staff are less well known. This paper reports the results of an online survey of 537 healthcare staff. Our study demonstrated an increased rate of patient referral for CAM from both personal CAM users and those trained in CAM. There was a high level of optimism amongst respondents as to the role CAM may play in patient care with mental health, depression and palliative care cited as the areas with highest expected benefit. Doctors were generally less optimistic about the likelihood of benefit compared to other healthcare staff. Implications for clinical practice, future research and staff education are discussed.. ...
Transfer Pathway Option 1: Are you already a qualified, certified instructor for a different, recognized First Aid agency, such as St. Johns Ambulance or the Life Saving Society? You can qualify for this transfer pathway. Youll complete the Fundamentals of Instruction, including the online learning and the two in-class days, but you will be exempt from the two days of Discipline-Specific first aid and CPR classroom instruction. Instead, youll move right to the Teaching Experience step.. Transfer Pathway Option 2: Are you a current Canadian Red Cross Water Safety Instructor or Instructor Trainer, or alternatively, are you a teacher at the elementary or secondary level? You can qualify for this transfer pathway. Youll complete the online learning (Fundamentals of Instruction), but you are exempt from the two days of Fundamentals of Instruction classroom instruction. Instead, youll move straight to the two days of Discipline Specific classroom instruction.. If you have any questions, dont ...
Required reading for students in medicine, nursing, public & community health, dentistry, pharmacy, & allied health sciences, A Study Guide to Epidemiology & Biostatistics contains clear & succinct explanations of complex topics. Successfully used by thousands of students, heres the one & only comprehensive study guide that will expose your students to all of the basic principles of epidemiology & biostatistics, help your students understand biostatistics & epidemiology without becoming bogged down in mathematical computation, & enable students & health professionals to intelligently read & appraise the health literature.Morton, Richard F. is the author of Study Guide to Epidemiology and Biostatistics - J. Richard Hebel - Hardcover - 3rd ed with ISBN 9780834201576 and ISBN 0834201577. [read more] ...
Find Your People Study Guide plus Streaming Video Book Description : This Study Guide includes: Individual access to 8 streaming video sessions Discussion and reflection questions with video notes Personal study between sessions Leaders Guide Never in the history of civilization have we been more connected and felt more alone. We are all so lonely. What if fundamentally the ways we have set up our lives is broken? Weve withdrawn rather than moved through it. We want supper clubs and friends, instead of war partners. We have a wrong view of community. This 8-session video Bible study begins with a look at the original community in Genesis, the Trinity, and the creation of people to see what God had planned for us all along. We will also discover throughout the study the five life patterns required to build deep, connected relationships: Proximity Shared Mission Transparency Accountability Consistency The eight sessions include: Week 1: Introduction / Gods Plan It is not good for man to be ...
Essential reading for students & health professionals in medicine, nursing, public & community health, dentistry, pharmacy, & allied health sciences, A Study Guide to Epidemiology & Biostatistics contains clear & succinct explanations of complex topics. Each chapter contains two components: the study notes & the exercises. The study notes briefly explain the major issues of a given topic. The exercises component requires you to apply the knowledge gained from epidemiology examples. Successfully used by thousands, its the one & only comprehensive study guide that will expose you to all of the basic principles of epidemiology & biostatistics, help you understand biostatistics & epidemiology without becoming bogged down in mathematical computation, & enable you to intelligently read & appraise the health literature. It is a must-have resource for those who will become users of epidemiological reports.Hebel, J. Richard is the author of Study Guide to Epidemiology and Biostatistics, published 2001 ...
A one-stop study resource for nutrition. Study Guide to accompany Nutrition: Everyday Choices is an important resource for students of nutrition, offering a host of tools to make study time more efficient and more effective. Aligned chapter-by-chapter with the textbook, this guide gives you everything you need to fully internalize essential information. Each chapter includes a condensed overview of the topic, an outline of chapter topics, key vocabulary, practice questions, and exercises in multiple-choice, true/false, and matching format. Focused, productive study leads to information retention, and nutrition students will value the resources provided in this study guide. ...
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During his internship at Willow Garage, Pablo Speciale a masters student from Vibot worked on allowing robots to better perceive their environment by improving calibration across multiple RGB cameras. Proper calibration allows robots to accurately interact with their environment by combining measurements from different cameras in an optimization process. In this method, calibration is obtained by minimizing the reprojection error with a non-linear solver (in our case, Ceres Solver). The approach starts off with the assumption that one camera is already calibrated with respect to the robot. Next, an initial calibration from the robot model is taken. This solution is able to estimate the best relative position between cameras by taking measurements of 2D patterns, in our case, a checkerboard thats held by the PR2. By using this process, proper calibration is achieved when all points move as a rigid entity during movement of the robot and its joints.. The goal of this project was the creation of a ...
Extrinsically calibrating a multi camera system based on scene images only is in general a very difficult problem. One promising approach computes the extrinsic parameters from sufficiently many pairwise relative poses, which can be reasonably estimated even in case of very many incorrectly matched point correspondences. Obviously, the quality of the calibration highly depends on the correctness of the relative pose estimates. As a limited number of relative poses suffices, we propose automatically selecting only the most reliable ones based on an uncertainty measure. Our selection criterion is equivalent to computing a shortest subgraph consisting of shortest triangle paths. The contribution of this paper consists of a mathematically rigorous proof of the correctness of an efficient algorithm for that problem. In experiments on synthetic and real data, we show that our selection algorithm produces greatly improved calibration results, both, in case of varying portions of outliers as well as varying
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Orchestra Baobab. According to the band, this could be a result of the many different musical experiences the guitarist, Charles Ndiaye, and Seck have had since the song was first written.. The confluence of different musical traditions, languages, sources of songs and instruments in Orchestra Baobabs music makes for a rich listening experience, but reading the lyrics and knowing some of their histories makes it even richer.. Gems like a beautiful woman can never pass away (from Mariama) and the shame that I have for my love for you might cause betrayal (from Magnokouto), even plainer ones like a good marriage is beyond price, are lost on the many who would understandably not think or bother to dig up lyrics to each song on A Tribute.... Album liner notes are going the way of the compact disks theyve long accompanied. Though all the lyrics on A Tribute… are published online, the guess is that only the particularly ardent fan will find and read the lyrics while listening to the ...
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Now in a revised and expanded second edition, this popular text provides a comprehensive introduction to the study of persuasive messages and their effects. Concepts and methods from communication and social psychology are seamlessly integrated to give students a solid grasp of foundational issues in persuasion research, the core features of persuasive transactions, and major models of persuasive communication. Retaining the clear organization and wealth of concrete examples that distinguished the original text, the second edition has been updated throughout with new data and theoretical developments. Two entirely new chapters cover the role of emotional appeals in persuasive transactions and the nature of resistance to interpersonal influence, among other topics.
HIGH POINT, N.C., Dec. 4, 2013 - Dr. Kirstin Squint, assistant professor of English at High Point University, was recently elected to the Executive Council of the Society for the Study of Southern Literature.. Squint, who will serve a three-year term as an SSSL Executive Council member, specializes in U.S. multi-ethnic literature. Her current research focuses on Native American literature of the South.. It is an honor for me to be elected to the SSSL Executive Council, Squint says. I am looking forward to serving an organization whose members engage in rigorous scholarly activity and who support and promote literature of the U.S. South.. Squint regularly teaches literature by multi-ethnic Southern writers, and her participation in SSSL helps to maintain the currency with theoretical developments in the field. Participation in the group has also given her an opportunity to network with numerous writers and scholars through the groups biennial conference.. The SSSL, a nonprofit organization ...
The cognitive sciences are currently witnessing a surge of research that integrates questions that traditionally were the prerogative of the social sciences and humanities. One cornerstone of this development is an anti-Cartesian view of the human body as a shaper of higher cognition, somewhat parallel to the much cited body-turn in the social sciences. A growing camp of cognitive scientists now emphasizes that cognition is not disconnected from the human body, but grounded in sensory percepts, affect and other inner somatic experience, as well as imagery and sensorimotor activations. The debate revolves around the catchwords embodiment (of language or thought) and (perceptual) grounding or perceptual simulation. In this essay I will introduce empirical and theoretical developments of this field. The perspective applied takes into view the contribution of the body and bodily experience to cognition, thereby opening a compellingly fresh vista on ancient quandaries about the human ...
This dissertation addresses the anomalous properties of water at high temperatures near the vapor-liquid critical point and at low temperatures in the supercooled liquid region. The first part of the dissertation is concerned with the concentration dependence of the critical temperature, density, and pressure of an aqueous sodium chloride solution. Because of the practical importance of an accurate knowledge of critical parameters for industrial, geochemical, and biological applications, an empirical equation for the critical locus of aqueous sodium chloride solutions was adopted in 1999 by the International Association for the Properties of Water and Steam (IAPWS) as a guideline. However, since this original ,italic,Guideline on the Critical Locus of Aqueous Solutions of Sodium Chloride,/italic, was developed, two new theoretical developments occurred, motivating the first part of this dissertation. Here, I present a theory-based formulation for the critical parameters of aqueous sodium ...
Changes in conscious level have been associated with changes in dynamical integration and segregation among distributed brain regions. Recent theoretical developments emphasize changes in directed functional (i.e., causal) connectivity as reflected in quantities such as integrated information and causal density. Here we develop and illustrate a rigorous methodology for assessing causal connectivity from electroencephalographic (EEG) signals using Granger causality (GC). Our method addresses the challenges of non-stationarity and bias by dividing data into short segments and applying permutation analysis. We apply the method to EEG data obtained from subjects undergoing propofol-induced anaesthesia, with signals source-localized to the anterior and posterior cingulate cortices. We found significant increases in bidirectional GC in most subjects during loss-of-consciousness, especially in the beta and gamma frequency ranges. Corroborating a previous analysis we also found increases in synchrony in
The Positivity Project, also referred to as P2, uses 24 character strengths to help students build positive relationships. Positive relationships are the cornerstone to health, happiness and resilience. Each week all children in grades kindergarten through fifth grade will be introduced and explicitly taught the same character strength. Everyone in our Long Meadow family will be provided with the same definition for each character strength. This common language along with classroom instruction tailored to each grade level, will help to provide students with a deeper understanding of each character trait. Children will soon be able to see what the character trait looks like through the use of videos, books, and discussions. Children will be able to identify character traits in themselves and others ...
The Positivity Project, also referred to as P2, uses 24 character strengths to help students build positive relationships. Positive relationships are the cornerstone to health, happiness and resilience. Each week all children in grades kindergarten through fifth grade will be introduced and explicitly taught the same character strength. Everyone in our Long Meadow family will be provided with the same definition for each character strength. This common language along with classroom instruction tailored to each grade level, will help to provide students with a deeper understanding of each character trait. Children will soon be able to see what the character trait looks like through the use of videos, books, and discussions. Children will be able to identify character traits in themselves and others ...
FOR IMMEDIATE RELEASE July 2, 2020Department of Education Releases Statewide Survey to Inform Framework for Returning to Classroom Instruction Maine Department of Education continues to work with educators and health experts from across the State to develop health markers and corresponding plans to ensure the safe return to classroom instruction. As this work develops, the Department…. Read More ...
A calibration approach was developed to correct for systematic between-cohort dietary measurement errors in the European Prospective Investigation into Cancer and Nutrition (EPIC), a large multicenter cohort study. To validate the 24-h diet recalls (24-HDRs) as reference measurements for between-cohort calibration, we estimated the agreement between center mean nitrogen (N) and total energy intakes and mean 24-h urinary N. Similar analyses using N and energy intake data from different dietary questionnaires (DQs) used at study baseline were conducted to estimate the effect of the calibration approach. This study was conducted between 1995 and 1999, and involved 1103 volunteers of both genders from 12 centers participating in European Prospective Investigation into Cancer and Nutrition. Pearsons correlation coefficients were weighted for study center sample size. When both genders were considered together (n = 22), the correlation coefficients between the center mean log-transformed urinary estimates
Nick serves as a Senior Account Manager at Learning Pool, with a specific focus on ensuring that clients meet and exceed their goals around L&D. He began his learning career in a traditional classroom environment, where he acted as a Graduate Teaching Fellow at Radford University. During this time he led the classroom instruction for Public Speaking, Critical Thinking, and Communication Theory courses. While his career has led him to pursue various roles within the public relations and staffing industry, his passion for education has brought him to return to a career in learning technology with Learning Pool. In his time at Learning Pool, Nick has helped to drive the success of clients such as Royal Caribbean, Indeed, Veterans Affairs, and US Public Health Service Commissioned Corps.. When he is not working to ensure the success of his clients L&D initiatives, you can find Nick enjoying the great outdoors. As an avid fisherman, bowhunter, kayaker and mountain biker, Nick is most at home when he ...
Can the Beatles do it again? Back in the 80s, when the groups original British albums were reissued on compact disc, music fans who had been skeptical about replacing their vinyl records could hold out no longer, thus giving the rising CD format a huge push toward its current dominance. Now the new kid on the home-video block is Digital Video (or Versatile) Disc DVD the movie-on-a-CD that offers superlative picture and sound. The first DVD
0129] The computer system 1400 may include a memory 1404 that can communicate via a bus 1408. The memory 1404 may be a main memory, a static memory, or a dynamic memory. The memory 1404 may include, but is not limited to computer readable storage media such as various types of volatile and non-volatile storage media, including but not limited to random access memory, read-only memory, programmable read-only memory, electrically programmable read-only memory, electrically erasable read-only memory, flash memory, magnetic tape or disk, optical media and the like. In one embodiment, the memory 1404 includes a cache or random access memory for the processor 1402. In alternative embodiments, the memory 1404 is separate from the processor 1402, such as a cache memory of a processor, the system memory, or other memory. The memory 1404 may be an external storage device or database for storing data. Examples include a hard drive, compact disc (CD), digital video disc (DVD), memory card, memory stick, ...
0182]The computer system 1500 may include a memory 1504 that can communicate via a bus 1508. The memory 1504 may be a main memory, a static memory, or a dynamic memory. The memory 1504 may include, but may not be limited to computer readable storage media such as various types of volatile and non-volatile storage media, including but not limited to random access memory, read-only memory, programmable read-only memory, electrically programmable read-only memory, electrically erasable read-only memory, flash memory, magnetic tape or disk, optical media and the like. In one case, the memory 1504 may include a cache or random access memory for the processor 1502. Alternatively or in addition, the memory 1504 may be separate from the processor 1502, such as a cache memory of a processor, the system memory, or other memory. The memory 1504 may be an external storage device or database for storing data. Examples may include a hard drive, compact disc (CD), digital video disc (DVD), memory card, ...
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Use this extensive study guide to help you review topics you will be tested on when taking the DSST Business Ethics and Society exam. In just a...