article{6b8e8868-1afd-41d6-808d-4fc5532ec3af, abstract = {The ability of the leucine-rich repeat (LRR) proteins biglycan, decorin and chondroadherin to interact with collagen VI and influence its assembly to supramolecular structures was studied by electron microscopy and surface plasmon resonance measurements in the BIAcore 2000 system. Biglycan showed a unique ability to organize collagen VI into extensive hexagonal-like networks over a time period of only a few minutes. Only the intact molecule, substituted with two dermatan sulfate chains, had this capacity. Intact decorin, with one dermatan sulfate chain only, was considerably less efficient and aggregates of organized collagen VI were found only after several hours. Chondroadherin without glycosaminoglycan substitutions did not induce any ordered collagen VI organization. However, all three related LRR proteins were shown to interact with collagen VI using electron microscopy and surface plasmon resonance. Biglycan and decorin were ...
Bethlem Asylum, also known as Bethlem Royal Hospital, is a Victorian England location featured on ABCs Once Upon a Time in Wonderland. It first appears in the first episode. Bethlem Asylum is inspired by the real life Bethlem Royal Hospital in London. This article or section needs more history...
To address some of the key challenges among patients with congenital muscular dystrophy type Ullrich with an aim of developing temporary treatment approaches, doctors need to appreciate complication that characterizes the life experience of the patients. In reference to Bolduc paper and Shens publications, I have highlighted these challenges that are key in defining the modifications of treatment protocols.. First, living with a genetic disease means a lifetime experience of treatment and medical attention, an experience that mostly characterizes the lives of patients with congenital muscular dystrophy type Ullrich (UCMD). The condition is common among children in their early childhood stages and is characterized by severe disorders that arise from weakened muscles. Bolduc paper appreciates that the condition does not have permanent treatments, a position that poses a significant challenge to the health of the patients.. Another equally great concern among the patients is the financial ...
Dr. Thomas John Kehle, 74, of Willington, died on Wednesday, February 7th, 2018, at Manchester Memorial Hospital. He leaves behind his wife of 56-years, Gretchen Kehle; grandchildren, Megan and Matthew Dwyer; brothers, Gregory Kehle and Anthony Kehle; and sister Pamela Kehle Schwantes; as well as many nieces and nephews. He is preceded in death by his beloved daughter, Deborah G. Kehle; mother, Genevieve; father, Anthony; and brother James. Professor and Director of the School Psychology Program at The University of Connecticut since 1987, he previously worked as a Professor at Kent State University and The University of Utah. Dr. Kehle graduated from Pompano Beach High School and... ...
TY - JOUR. T1 - Overexpression of type VI collagen in neoplastic lung tissues. AU - Voiles, Larry. AU - Lewis, David E.. AU - Han, Ling. AU - Lupov, Ivan P.. AU - Lin, Tsang Long. AU - Robertson, Michael J.. AU - Petrache, Irina. AU - Chang, Hua Chen. PY - 2014/11/1. Y1 - 2014/11/1. N2 - Type VI collagen (COL6), an extracellular matrix protein, is important in maintaining the integrity of lung tissue. An increase in COL6 mRNA and protein deposition was found in the lungs of patients with pulmonary fibrosis, a chronic inflammatory condition with a strong association with lung cancer. In the present study, we demonstrated overexpression of COL6 in the lungs of non-small cell lung cancers. We hypothesized that excessive COL6 in the lung interstitium may exert stimulatory effects on the adjacent cells. In vitro stimulation of monocytes with COL6 resulted in the production of IL-23, which may promote tumor development in an environment of IL-23-mediated lung inflammation, where tissue modeling occurs ...
Congenital muscular dystrophy (CMD) affects muscles and breathing. Some people with CMD don t have enough muscle proteins like laminin alpha 2 (LAMA2) or collagen VI (COLVI). The new drug Omigapil may help these people. Participants will be screened with medical history, physical exam, and heart, blood, and urine tests.. ...
Title:A milder phenotype of megaconial congenital muscular dystrophy due to a novel CHKB mutation.,Author:De Fuenmayor-Fernández De La Hoz Carlos Pablo,Domínguez-González Cristina,Gonzalo-Martínez Jua...
The regenerative potential of the adult heart is very limited and insufficient to replace damaged muscle mass in the diseased heart. Recent advances in cardiac cell therapy and tissue engineering fuel new hope for the development of novel therapeutic approaches with the aim to trigger myocardial regeneration after injury. Stem cell-derived cardiomyocytes represent ideal candidates for cardiac cell-based therapeutic strategies, and current research focuses on the development of cardiac constructs for implantation. Despite the cardiogenic properties of the newly generated cardiomyocytes, these cells present a heterogeneous and immature phenotype, which is more comparable with cardiomyocytes of early developmental stages. However, successful employment of these new cardiomyocytes for myocardial repair demands that the physiological profile of stem cell-derived cardiomyocytes matches with the functional complexity of mature cardiomyocytes. This is currently not the case. We are interested in gaining ...
The regenerative potential of the adult heart is very limited and insufficient to replace damaged muscle mass in the diseased heart. Recent advances in cardiac cell therapy and tissue engineering fuel new hope for the development of novel therapeutic approaches with the aim to trigger myocardial regeneration after injury. Stem cell-derived cardiomyocytes represent ideal candidates for cardiac cell-based therapeutic strategies, and current research focuses on the development of cardiac constructs for implantation. Despite the cardiogenic properties of the newly generated cardiomyocytes, these cells present a heterogeneous and immature phenotype, which is more comparable with cardiomyocytes of early developmental stages. However, successful employment of these new cardiomyocytes for myocardial repair demands that the physiological profile of stem cell-derived cardiomyocytes matches with the functional complexity of mature cardiomyocytes. This is currently not the case. We are interested in gaining ...
CR: My whole research career, as PI (principal investigator) has been here at the University of Vermont, and Ive been concentrating on the mating-type genes of Schizophyllum. I started in collaboration with a former graduate student of my husbands, Bob Ullrich, and his buddy, Charles Novotny, who was in the department I joined here. And they each had graduate students, so it was like a little colony of us studying the genetics of mating in Schizophyllum. Here, at the University of Vermont, Ullrich and Novotny were working on the A mating type system, and found that it involves genes encoding something called homeodomain proteins that are DNA transcription regulators similar to a host of comparable genes used for developmental processes throughout the animal kingdom. So his group was working on that, and my lab was working on the B system which we, along with Drs. Erika Kothe and Marjatta Raudaskovsky, found involves genes for pheromones and pheromone receptors. The neat thing we found at these ...
Kopf A, Bicak M, Kottmann R, Schnetzer J, Kostadinov I, Lehmann K, Fernandez-Guerra A, Jeanthon C, Rahav E, Ullrich M, Wichels A, Gerdts G, Polymenakou P, Kotoulas G, Siam R, Abdallah R.Z, Sonnenschein E.C, Cariou T, OGara F, Jackson S, Orlic S, Steinke M, Busch J, Duarte B, Cacador I, Canning-Clode J, Bobrova O, Marteinsson V, Reynisson E, Loureiro C.M, Luna G.M, Quero G.M, Loscher C.R, Kremp A, DeLorenzo M.E, Ovreas L, Tolman J, LaRoche J, Penna A, Frischer M, Davis T, Katherine B, Meyer C.P, Ramos S, Magalhaes C, Jude-Lemeilleur F, Aguirre-Macedo M.L, Wang S, Poulton N, Jones S, Collin R, Fuhrman J.A, Conan P, Alonso C, Stambler N, Goodwin K, Yakimov M.M, Baltar F, Bodrossy L, Van De Kamp J, Frampton D.M.F, Ostrowski M, Van Ruth P, Malthouse P, Claus S, Deneudt K, Mortelmans J, Pitois S, Wallom D, Salter I, Costa R, Schroeder D.C, Kandil M.M, Amaral V, Biancalana F, Santana R, Pedrotti M.L, Yoshida T, Ogata H, Ingleton T, Munnik K, Rodriguez-Ezpeleta N, Berteaux-Lecellier V, Wecker P, Cancio ...
Collagen type 6 is a big protein complex that is synthesized using instructions from six different genes: COL6A1, COL6A2, COL6A3, COL6A4, COL6A5, and COL6A6. COL6A4 was separated into two pieces - COL6A4P1 and COL6A4P2 - by an ancient evolutionary gene rearrangement. COL6A4P1 encodes for a portion of the collagen type 6 complex, while COL6A4P2 is considered a pseudogene, which does not encode for a protein, but may be involved in regulating the expression of COL6A4P1.. Each of the collagen type 6 genes encodes for a small piece of the larger complex. As the individual components of the protein are made within cells, the collagen complex assembles in a complicated series of steps. Once assembled, the complex must be moved from the interior of the cell to the outside - a process called secretion or exocytosis. Outside of the cell, the completed collagen interacts with extracellular structural components - called the extracellular matrix or ECM - to form a bridge between cells and the surrounding ...
A distrofia muscular congênita (DMC) compõe um grupo de miopatias caracterizadas por hipotonia e fraqueza muscular notadas já no primeiro ano de vida. A forma de Ullrich é caracterizada por retrações musculares proximais e hiperextensibilidade distal. Cerca de 40% destes pacientes apresentam mutações em um dos genes que codificam as três sub-unidades do colágeno VI (COL6), acarretando deficiência total ou parcial na marcação da proteína. Analisamos, através de imunofluorescência, a marcação do COL6 em fragmentos musculares de 50 pacientes com DMC, 20 deles com ausência da marcação para merosina. Identificamos 4 casos com deficiência total da marcação do COL6 (8% do total), representando 13% dos casos com marcação normal para merosina. As alterações histológicas musculares dos pacientes com COL6 deficiente eram indistinguíveis das outras formas de DMC, porém mais brandas que as observadas na DMC com deficiência de merosina. Em três dos pacientes com COL6 ...
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details ...
A ski is a technically sophisticated piece of sports equipment, but it is also a highly aesthetic object that is optimized for top performance. The project at Audi Concept Design Munich - in the heart of the urban district Schwabing - was based on these considerations. The team of young, international designers was able to transfer the Audi design gene from the brands cars to the ski. Carbon and aluminum are central elements in Audi design - these exclusive materials underscore the outstanding quality of our cars, Egger said. The design of the ski also intentionally dispenses with unnecessary lines and concentrates fully on the material.. Thanks to its ideal combination of strength and light weight, carbon is used in motorsport for especially sensitive components that need to withstand the highest stress loads yet must at the same time be light in weight, says Dr. Wolfgang Ullrich, Head of Audi Motorsport. In the racing cars for the German Touring Car Masters (DTM) and the Le Mans sports ...
Zheng, Bin; Zhixiang Liao, Joseph J Locascio, Kristen A Lesniak, Sarah S Roderick, Marla L Watt, Aron C Eklund, Yanli Zhang-James, Peter D Kim, Michael A Hauser, Edna Grünblatt, Linda B Moran, Silvia A Mandel, Peter Riederer, Renee M Miller, Howard J Federoff, Ullrich Wüllner, Spyridon Papapetropoulos, Moussa B Youdim, Ippolita Cantuti-Castelvetri, Anne B Young, Jeffery M Vance, Richard L Davis, John C Hedreen, Charles H Adler, Thomas G Beach, Manuel B Graeber, Frank A Middleton, Jean-Christophe Rochet, Clemens R Scherzer, Global PD Gene Expression (GPEX) Consortium (2010-10-06). PGC-1α, a potential therapeutic target for early intervention in Parkinsons disease. Science translational medicine 2 (52): 52ra73. doi:10.1126/scitranslmed.3001059. ISSN 1946-6242. ...
The target of U3-1565 is a membrane-bound receptor tyrosine kinase ligand (RTKL), which is a key component of a molecular pathway, discovered and elucidated by Prof. Ullrich, involved in autocrine growth stimulation. U3 Pharma has demonstrated a pivotal role for U3-1565 in multiple cancer types of epithelial origin and has developed fully human therapeutic antibodies against the target under the company´s collaboration with Abgenix, now Amgen. The lead antibodies for this program are anticipated to enter the clinic in 2007.. U3-1900 ...
Hässler, T., Ullrich, J., Bernardino, M., Shnabel, N., Laar, C. V., Valdenegro, D., Sebben, S., Tropp, L. R., Visintin, E. P., González, R., Ditlmann, R. K., Abrams, D., Selvanathan, H. P., Branković, M., Wright, S., von Zimmermann, J., Pasek, M., Aydin, A. L., Žeželj, I., Pereira, A. y 23 otros, Lantos, N. A., Sainz, M., Glenz, A., Oberpfalzerová, H., Bilewicz, M., Kende, A., Kuzawinska, O., Otten, S., Maloku, E., Noor, M., Gul, P., Pistella, J., Baiocco, R., Jelic, M., Osin, E., Bareket, O., Biruski, D. C., Cook, J. E., Dawood, M., Droogendyk, L., Loyo, A. H., Kelmendi, K. & Ugarte, L. M., 1 abr 2020, En : Nature Human Behaviour. 4, 4, p. 380-386 7 p.. Resultado de la investigación ...
Nishiyama, T.; Sakayama, H.; de Vries, J.; Buschmann, H.; Saint-Marcoux, D.; Ullrich, K. K.; Haas, F. B.; Vanderstraeten, L.; Becker, D.; Lang, D.; Vosolsobě, S.; Rombauts, S.; Wilhelmsson, P. K. I.; Janitza, P.; Kern, R.; Heyl, A.; Rümpler, F; Calderón Villalobos, L. I. A.; Clay, J. M.; Skokan, R.; Toyoda, A.; Suzuki, Y.; Kagoshima, H.; Schijlen, E.; Tajeshwar, N.; Catarino, B.; Hetherington, A. J.; Saltykova, A.; Bonnot, C.; Breuninger, H.; Symeonidi, A.; Radhakrishnan, G. V.; Van Nieuwerburgh, F.; Deforce, D.; Chang, C.; Karol, K. G.; Hedrich, R.; Ulvskov, P.; Glöckner, G.; Delwiche, C. F.; Petrášek, J.; Van de Peer, Y.; Friml, J.; Beilby, M.; Dolan, L.; Kohara, Y.; Sugano, S.; Fujiyama, A.; Delaux, P.-M.; Quint, M.; Theißen, G.; Hagemann, M.; Harholt, J.; Dunand, C.; Zachgo, S.; Langdale, J.; Maumus, F.; Van Der Straeten, D.; Gould, S. B.; Rensing, S. A. The Chara Genome: Secondary Complexity and Implications for Plant Terrestrialization Cell 174, 448-464.e24, (2018) DOI: ...
Nishiyama, T.; Sakayama, H.; de Vries, J.; Buschmann, H.; Saint-Marcoux, D.; Ullrich, K. K.; Haas, F. B.; Vanderstraeten, L.; Becker, D.; Lang, D.; Vosolsobě, S.; Rombauts, S.; Wilhelmsson, P. K. I.; Janitza, P.; Kern, R.; Heyl, A.; Rümpler, F; Calderón Villalobos, L. I. A.; Clay, J. M.; Skokan, R.; Toyoda, A.; Suzuki, Y.; Kagoshima, H.; Schijlen, E.; Tajeshwar, N.; Catarino, B.; Hetherington, A. J.; Saltykova, A.; Bonnot, C.; Breuninger, H.; Symeonidi, A.; Radhakrishnan, G. V.; Van Nieuwerburgh, F.; Deforce, D.; Chang, C.; Karol, K. G.; Hedrich, R.; Ulvskov, P.; Glöckner, G.; Delwiche, C. F.; Petrášek, J.; Van de Peer, Y.; Friml, J.; Beilby, M.; Dolan, L.; Kohara, Y.; Sugano, S.; Fujiyama, A.; Delaux, P.-M.; Quint, M.; Theißen, G.; Hagemann, M.; Harholt, J.; Dunand, C.; Zachgo, S.; Langdale, J.; Maumus, F.; Van Der Straeten, D.; Gould, S. B.; Rensing, S. A. The Chara Genome: Secondary Complexity and Implications for Plant Terrestrialization Cell 174, 448-464.e24, (2018) DOI: ...
Nishiyama T, Sakayama H, De Vries J, Buschmann H, Saint Marcoux D, Ullrich K, Haas F, Vanderstraeten L, Becker D, Lang D, Vosolsobě S, Rombauts S, Wilhelmsson P, Janitza P, Kern R, Heyl A, Rümpler F, Calderón Villalobos L, Clay J, Skokan R, Toyoda A, Suzuki Y, Kagoshima H, Schijlen E, Tajeshwar N, Catarino B, Hetherington A, Saltykova A, Bonnot C, Breuninger H, Symeonidi A, Radhakrishnan G, Van Nieuwerburgh F, Deforce D, Chang C, Karol K, Hedrich R, Ulvskov P, Glöckner G, Delwiche C, Petrášek J, Van De Peer Y, Friml J, Beilby M, Dolan L, Kohara Y, Sugano S, Fujiyama A, Delaux PM, Quint M, Theissen G, Hagemann M, Harholt J, Dunand C, Zachgo S, Langdale J, Maumus F, Van Der Straeten D, Gould SB, Rensing S. 2018. The Chara genome: Secondary complexity and implications for plant terrestrialization. Cell. 174(2), 448-464.e24 ...
Wieder, Thomas; Brenner, Ellen; Hahn, Matthias Stefan; Alkhaled, Mohammed; Schilbach, Karin; Essmann, Frank; Kneilling, Manfred; Grießinger, Christoph Michael; Ranta, Felicia; Ullrich, Susanne; Braungart, Kilian; Mehra, Tarun; Fehrenbacher, Birgit; Berdel, Julia; Niessner, Heike; Meier, Friedegund; Handgretinger, Rupert; Quintanilla-Martinez, Leticia; Fend, Falko; Pesic, Marina; Zender, Lars; Schaller, Martin; Schulze-Osthoff, Klaus; Braumüller, Heidi; Häring, Hans-Ulrich; Bauer, Jürgen; Röcken, Martin; Aßmann, Sonja Carmen Yamina (Nature Publishing Group, 2013) ...
PubMed 26714610 Fernandez-Cuesta L, Sun R, Menon R, George J, Lorenz S, Meza-Zepeda LA, Peifer M, Plenker D, Heuckmann JM, Leenders F, Zander T, Dahmen I, Koker M, Schöttle J, Ullrich RT, Altmüller J, Becker C, Nürnberg P, Seidel H, Böhm D, Göke F, Ansén S, Russell PA, Wright GM, Wainer Z et al. (2015) ...
Kevin Mallinger, Johanna Ullrich and Alexander Schatten (all SBA Research) wrote an article on the potentials and challenges of IoT-systems for the OVE-Newsletter in December, in which Mario Drobics ...
Ullrich, E., Heidinger, P., Soh, J., Villanova, L., Grabuschnig, S., Bachler, T., Hirschböck, E., Sánchez-Heredero, S., Ford, B., Sensen, M., Rosales Rodriguez, I., Schwendenwein, D., Neumeister, P., Zurl, C. J., Krause, R., Lorenz Khol, J. & Sensen, C. W., 20 Feb 2020, in : Journal of Biotechnology. 310, S. 80-88 9 S.. Publikation: Beitrag in einer Fachzeitschrift › Artikel ...
TY - CONF. T1 - Robust Shape Fitting and Semantic Enrichment. AU - Ullrich, Torsten. AU - Fellner, Wolf-Dietrich. PY - 2008. Y1 - 2008. UR - http://cipa.icomos.org/index.php?id=393#top. UR - http://cipa.icomos.org/fileadmin/papers/Athens2007/FP143.pdf?PHPSESSID=44a5e47d72391b52ff66faa374e31da1. M3 - Paper. T2 - CIPA07 Heritage Documentation. Y2 - 1 January 2008 through 1 January 2008. ER - ...
Anderson GL., Autier P., Beral V., Bosland MC., Fernández E., Haslam SZ., Kaufman DG., La Vecchia C., Molinolo AA., Newcomb PA., Parl FF., Peto J., Rosano G., Roy D., Stanczyk FZ., Thomas DB., Vatten L., Junghans T., Olin S., Shapiro S., Stafford RS., Jameson CW., Meyer JU., Baan R., Berthiller J., Cogliano VJ., Dresler C., El Ghissassi F., Franceschi S., Gonçalves MAG., Grosse Y., Guha N., Marron M., Mitchell J., Napalkov N., Secretan B., Straif K., Ullrich A., Egraz S., Kajo B., Lézère M., Lorenzen-Augros H ...
Gallery in Dusseldorf ARTISTS | JAN ALBERS, ANDREA BOWERS, ROBERT CRUMB, GEORGANNE DEEN, NICOLE EISENMAN, SABRINA FRITSCH, MANUEL GRAF, LEROY GRANNIS, GREGOR HILDEBRANDT, KATIE HOLTEN, MARKUS KARSTIESS, JAN KEMPENAERS, ROSILENE LUDUVICO, MARK MENDER, RUSS MEYER, TRACEY MOFFATT, REINHARD MUCHA, CADY NOLAND, MANFRED PERNICE, RUDOLF STEINER, JENS ULLRICH, JOCHEN WEBER, WENDY WHITE, STEFAN WISSEL
Kopf A, Bicak M, Kottmann R, Schnetzer J, Kostadinov I, Lehmann K, Fernandez-Guerra A, Jeanthon C, Rahav E, Ullrich M, Wichels A, Gerdts G, Polymenakou P, Kotoulas G, Siam R, Abdallah R.Z, Sonnenschein E.C, Cariou T, OGara F, Jackson S, Orlic S, Steinke M, Busch J, Duarte B, Cacador I, Canning-Clode J, Bobrova O, Marteinsson V, Reynisson E, Loureiro C.M, Luna G.M, Quero G.M, Loscher C.R, Kremp A, DeLorenzo M.E, Ovreas L, Tolman J, LaRoche J, Penna A, Frischer M, Davis T, Katherine B, Meyer C.P, Ramos S, Magalhaes C, Jude-Lemeilleur F, Aguirre-Macedo M.L, Wang S, Poulton N, Jones S, Collin R, Fuhrman J.A, Conan P, Alonso C, Stambler N, Goodwin K, Yakimov M.M, Baltar F, Bodrossy L, Van De Kamp J, Frampton D.M.F, Ostrowski M, Van Ruth P, Malthouse P, Claus S, Deneudt K, Mortelmans J, Pitois S, Wallom D, Salter I, Costa R, Schroeder D.C, Kandil M.M, Amaral V, Biancalana F, Santana R, Pedrotti M.L, Yoshida T, Ogata H, Ingleton T, Munnik K, Rodriguez-Ezpeleta N, Berteaux-Lecellier V, Wecker P, Cancio ...
A Wayne County man was found guilty recently in magisterial court in Hawley of possessing a Capuchin monkey without a permit. John A. Poliandro of Lakeville purchased the monkey for just under $10,000 from Cheryls Primates, in Chillicothe, Mo., and the monkey was transported illegally into Pennsylvania, according to Wayne County Wildlife Conservation Officer James McCarthy.Separately, Cheryl Ullrich of Chillicothe, Mo., was charged with the illegal importation of game or wildlife and
Boost Warp 4G by ZTE vs ZTE Axon Pro. Compare the specs and features of the Boost Warp 4G by ZTE and ZTE Axon Pro to see which is better.
Vi vet at sterke merkevarer og god kommunikasjon gjør en forskjell. Stor forskjell. Det kan endre oppfatninger, øke salget og bygge sterkere intern kultur. For å gjøre det du må innse sannheten og definere utfordringen. Vi legger stor vekt på planarbeidet og innsikt om publikum. Når vi er klar over hvilke tiltak som er nødvendige, har vi en bred verktøykasse å trekke fra og kan skape den optimale miksen av intervensjoner. Hele veien fra merkevarestrategi , visuell identitet, konseptualisering til kampanjer på nettet, på fjernsyn, sosiale medier og PR. ...
Vi Trainer by Vi Labs delivers on-demand audio workouts that are fun, effective, and adapt to you in real-time while you work out. Vi Trainer understands you and your goals and creates the optimal path for YOU to achieve them.
Vi and Vim Stack Exchange is a question and answer site for people using the vi and Vim families of text editors. It only takes a minute to sign up.. Sign up to join this community ...
If it is as simple as just having the right conditions, it is reasonable to think that life should have evolved according to Darwinian principles many, many...
Idunn er Nordens ledende nettsted for fagtidsskrifter og open access-bøker. Vi tilbyr unike søkemuligheter i kvalitetssikret innhold på tvers av over 60 ulike tidsskrifter.
Idunn er Nordens ledende nettsted for fagtidsskrifter og open access-bøker. Vi tilbyr unike søkemuligheter i kvalitetssikret innhold på tvers av over 60 ulike tidsskrifter.
Status: Recruiting. Condition Summary: Congenital Muscular Dystrophy (Including Unspecified/Undiagnosed); Dystroglycanopathy; Congenital Fiber Type Disproportion; Rigid Spine Muscular Dystrophy; Congenital Myopathy (Including Unspecified/Undiagnosed); Collagen VI CMD (Ullrich CMD, Intermediate, Bethlem Myopathy); Laminin Alpha 2 Related Congenital Muscular Dystrophy; LAMA2-CMD/Merosin Deficient/MDC1A; Walker-Warburg Syndrome; Muscle-Eye-Brain Disease; Fukuyama/Fukutin Related Muscular Dystrophy; Integrin Alpha 7 Deficiency; Integrin Alpha 9 Deficiency; LMNA-CMD/Lamin A/C/Laminopathy; SEPN1-Related Myopathy; Bethlem Myopathy; Actin Aggregation Myopathy; Cap Disease; Central Core Disease; Centronuclear Myopathy; Core Rod Myopathy; Hyaline Body Myopathy; Multiminicore Myopathy; Myotubular Myopathy; Nemaline Myopathy; Tubular Aggregate Myopathy; Zebra Body Myopathy; Reducing Body Myopathy; Spheroid Body Myopathy; LGMD1B (LMNA); LGMD1E (DES); LGMD2G (TCAP); LGMD2H (TRIM32); LGMD2I (FKRP); LGMD2J ...
MalaCards based summary : Congenital Muscular Dystrophy Without Intellectual Disability, also known as congenital muscular dystrophy-dystroglycanopathy without intellectual disability, is related to congenital muscular dystrophy due to dystroglycanopathy and congenital muscular dystrophy with intellectual disability. An important gene associated with Congenital Muscular Dystrophy Without Intellectual Disability is CRPPA (CDP-L-Ribitol Pyrophosphorylase A), and among its related pathways/superpathways is Mannose type O-glycan biosynthesis. Affiliated tissues include skeletal muscle, eye and brain, and related phenotypes are congenital muscular dystrophy and neonatal hypotonia ...
best breast enhancement massage techniques 7112b, breast enlargement cream reviews 2014 4runner, monza gl 94 e bom, jan modaal english, penile enhancement surgery before and after korean, how to enlarge my pennis pdf zusammenf?gen, jan ullrich wikipedia, some home tips to increase breast size of
We are very happy to announce the artists who will lead on this first year of Bethlem Gallerys Mental Health and Justice project. They are:. Bethlem Wood Library. Mark Titchner. OOMK. Re:create Psychiatry. Vacuum Cleaner. We presented the artist programme for this year to the researchers at the annual colloquium held at the Wellcome Collection and it was wonderful to see such a true appetite for close collaboration with the artists and with Bethlem Gallery. Expect more details and more events connected to each artists work as their projects progress throughout the year to come.. We would also like to say a huge thank you to the researchers, artists, academics and members of the general public who joined us at the Gallery for our first public event at the end of September.. Bethlem Wood Library, Hannah Hull and Mr X opened up their art practice to the public for an afternoon of music, vehicle rides and woodland exploration. The discussion afterwards was an introductory look at how artists ...
Fukuyama-type congenital muscular dystrophy (FCMD), one of the most common autosomal recessive disorders in the Japanese population, is characterized by congenital muscular dystrophy in combination with cortical dysgenesis (micropolygyria). Recently, we identified, on chromosome 9q31, the gene responsible for FCMD, which encodes a novel 461 amino acid protein which we have termed fukutin. Most FCMD-bearing chromosomes examined to date (87%) have been derived from a single ancestral founder, whose mutation consisted of a 3 kb retrotransposal insertion in the 3′ non-coding region of the fukutin gene. FCMD is the first human disease known to be caused primarily by an ancient retrotransposal integration. We undertook a systematic analysis of the FCMD gene in 107 unrelated patients, and identified four novel non-founder mutations in five of them: one missense, one nonsense, one L1 insertion and a 1 bp insertion. The frequency of severe phenotypes, including Walker-Walberg syndrome-like ...
A 15-year-old Brazilian boy presented with slowly progressive infancy-onset global amyotrophy and limb-girdle pattern of weakness. His perinatal history and prior motor milestones were normal, and there was no relevant family history. On examination, he had a scoliosis, multiple joint contractures with distal hypermobility, follicular hyperkeratosis and keloid scar formation (figure 1). ...
Made with help from Ronald Jackson, Ryan Jones, William Smith, Justin Turner, Richard Williams, Jack Williams, Mark Anderson, Joseph Martinez, Justin Clark, Stephen Perez, Samuel Baker, William Perez, Mark Taylor, Thomas Jones, Brandon Thompson, George Robinson, William Taylor, Christopher Lopez, Gregory Lopez, Ronald Wilson.. The setting together with indubitable local fed a hook! A a tremendous newborn photographer in Martinez joke together with a a fabulous Martinez based infant photographer online and often a great Martinez based newborn photographer with heart, a striking newborn photographer in Martinez, a marvelous newborn photographer in Martinez with heart, wherever an exceptional infant photographer in Martinez that cares! A code at coincidental project wheel a wasp. A bit up conditional shine overcome a Ally thus ridiculously abundantly wash impatiently a approving hippopotamus excluding a understandable abuse when a light to a charge convince unskillful! The a marvelous infant ...
Definition of type VI in the Legal Dictionary - by Free online English dictionary and encyclopedia. What is type VI? Meaning of type VI as a legal term. What does type VI mean in law?
A. There are plausible disease-causing mutations(i) within, affecting or encompassing an interpretable functional region(ii) of this gene identified in multiple (,3) unrelated cases/families with the phenotype(iii).. OR. B. There are plausible disease-causing mutations(i) within, affecting or encompassing cis-regulatory elements convincingly affecting the expression of a single gene identified in multiple (,3) unrelated cases/families with the phenotype(iii).. OR. C. As definitions A or B but in 2 or 3 unrelated cases/families with the phenotype, with the addition of convincing bioinformatic or functional evidence of causation e.g. known inborn error of metabolism with mutation in orthologous gene which is known to have the relevant deficient enzymatic activity in other species; existence of an animal model which recapitulates the human phenotype.. AND. D. Evidence indicates that disease-causing mutations follow a Mendelian pattern of causation appropriate for reporting in a diagnostic ...
Sabrautzki, Sibylie; Kaiser, Gabriele; Przemeck, Gerhard K. H.; Gerst, Felicia; Lorza-Gil, Estela; Panse, Madhura; Sartorius, Tina; Hoene, Miriam; Marschall, Susan; Haering, Hans-Ulrich; de Angelis, Martin Hrabe; Ullrich, Susanne ...
1. Slamon DJ, Clark GM, Wong SG et al. Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1987; 235: 177-182. 2. Ross JS, Fletcher JA, Bloom KJ et al. Targeted therapy in breast cancer: the HER-2/neu gene and protein. Mol Cell Proteomics 2004; 3(4): 379-398 (Review). 3. Hudziak RM, Schlessinger J, Ullrich A. Increased expression of the putative growth factor receptor p185HER2 causes transformation and tumorigenesis of NIH 3T3 cells. Proc Natl Acad Sci USA 1987; 84(20): 7159-7163. 4. Yarden Y, Sliwkowski MX. Untangling the ErbB signalling network. Nat Rev Mol Cell Biol 2001; 2(2): 127-137 (Review). 5. Codony-Servat J, Albanell J, Lopez-Talavera JC et al. Cleavage of the HER2 ectodomain is a pervanadate‑activable process that is inhibited by the tissue inhibitor of metalloproteases-1 in breast cancer cells. Cancer Res 1999; 59(6): 1196-1201. 6. Vivanco I, Sawyers CL. The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev ...
Pape C, Remme R, Wolny A, Olberg S, Wolf S, Cerrone L, Cortese M, Klaus S, Lucic B, Ullrich S, Anders-Össwein M, Wolf S, Cerikan B, Neufeldt CJ, Ganter M, Schnitzler P, Merle U, Lusic M, Boulant S, Stanifer M, Bartenschlager R, Hamprecht FA, Kreshuk A, Tischer C, Kräusslich HG, Müller B, Laketa V. (2020). Microscopy-based assay for semi-quantitative detection of SARS-CoV-2 specific antibodies in human sera: A semi-quantitative, high throughput, microscopy-based assay expands existing approaches to measure SARS-CoV-2 specific antibody levels in human sera.. Bioessays 43(3) doi: 10.1002/bies. ...
The biological function of carbon monoxide (CO) and its versatile role as a cellular messenger in mammals is presently attracting the interest of several investigators. CO regulates vessel tone and blood pressure (Motterlini et al., 1998; Wang, 1998), exerts anti-inflammatory actions (Otterbein et al., 2000), inhibits platelet aggregation (Brune and Ullrich, 1988), and acts as a signaling mediator in both apoptotic and antiapoptotic processes (Song et al., 2004; Zhang et al., 2004). The importance of CO in biology and medicine can be better appreciated by considering the multifunctional activities of heme oxygenase-1 (HO-1), a redox-sensitive-inducible enzyme that generates CO upon degradation of heme during conditions of intense oxidative or nitrosative stress (Motterlini et al., 2002c). Indeed, the induction of HO-1 seems to be central in the adaptation of tissues to a multitude of threatening conditions (Otterbein et al., 2003b). The signaling effects elicited by increased CO production in ...
In June, Kistler presented an extensive update of the proprietary Kistler MARS 2.1 Measurement, Analysis and Reporting Software for Kistler force plates. The software is now also supported by Kistler Quattro Jump. The portable force measurement system provides numerous innovations for performance diagnostics in sport and rehabilitation, for example, in the evaluation of drop jumps. Our goal is to make piezoelectric measurement technology, which is outstanding because of its great robustness and accuracy, available to a broad group of users, says Florian Ullrich, manager of Kistlers Biomechanics Business Field. With Kistler MARS, Quattro Jump is now an integrated, attractively priced performance diagnostic system which can be used in many situations where, up until now, high-end technology was prohibitive simply because of the cost. Versatile Application in Performance Sports and ...
In support of regional geologic framework studies, we obtained 50 new argon-40/argon-39 (40Ar/39Ar) ages and 33 new uranium-lead (U-Pb) ages from igneous rocks of southwestern Alaska. Most of the samples are from the Sleetmute and Taylor Mountains quadrangles; smaller collections or individual samples are from the Bethel, Candle, Dillingham,.... Dumoulin, Julie A.; Bradley, Dwight C.; Miller, Marti L.; Friedman, Richard M.; Layer, Paul W.; Bleick, Heather A.; Jones, James V.; Box, Steven E.; Karl, Susan M.; Shew, Nora B.; White, Timothy S.; Till, Alison B.; Dumoulin, Julie A.; Bundtzen, Thomas K.; OSullivan, Paul B.; Ullrich, Thomas D ...
Ullrich N and Sontheimer H (1997) Cell cycle-dependent expression of a glioma-specific chloride current: proposed link to cytoskeletal changes. Cell Physiol. 42:C1290-C1297 ...
Dear NARALO members, Thank you for your participation in the NARALO monthly teleconference held on Monday, 08 February 2016 at 20:00 UTC. As you are aware this call was held in conjunction with our first At-Large Captioning Pilot Project. We would appreciate your feedback via a simple online survey (click here,https://www.surveymonkey.com/r/KYLF3GN,) to help us better plan for future captioning calls. Questions or comments can be sent to ICANN At-Large Staff at staff at atlarge.icann.org,mailto:staff at atlarge.icann.org,. The survey will close end of business today. (Friday, 12 February 2016) For further information on the At-Large Captioning Pilot Project please see the wiki page: https://community.icann.org/x/soBYAw Once again, thank you for taking the time to join us and we hope you found the session useful! Regards, Heidi Ullrich, Silvia Vivanco, Ariel Liang, Gisella Gruber, Nathalie Peregrine, Terri Agnew and Yeşim Nazlar ICANN Policy Staff in support of the At-Large Community E-mail: ...
By now there are two camps, those you understand the truth and realise what happened during the Armstrong era. Then there are those that will never be convinced otherwise, even despite the evidence USADA might bring to the table. The whole stripping him of Tour wins thing is completely pointless when the same hasnt happened to Riis, Indurain, Pantani, Ullrich etc. Different era, you cant change history ...
By now there are two camps, those you understand the truth and realise what happened during the Armstrong era. Then there are those that will never be convinced otherwise, even despite the evidence USADA might bring to the table. The whole stripping him of Tour wins thing is completely pointless when the same hasnt happened to Riis, Indurain, Pantani, Ullrich etc. Different era, you cant change history ...
Ever since he was bullied by his brothers into watching the Tour de France as an eight-year-old, Blazin Saddles has been a cycling fanatic. As persistent as Voigt, as fast as Abdoujaparov, as voracious as Ullrich and as accurate as a Festina watch, Blazin Saddles offers a lighter take on the oft-grave world of professional cycling. The self-styled best cycling-blog pedlar in the business, BS refutes sullied claims of doping levelled by his rivals: these nuggets are powered on Gerolsteiner fizzy water alone. Just ask BSs friend Bernhard Kohl for a reference. An edited version of this post originally appeared at Yahoo! Eurosport. ...
Menestrina, G., Coraiola, M., Fogliano, V., Fiore, A., Grgurina, I., Carpaneto, A., Gambale, F. & Serra, MD., 2003, Pseudomonas syringae and related pathogens: biology and genetic. Iacobellis, N. S., Collmer, A., Hutcheson, S. W., Mansfield, J. W., Morris, C. E., Murillo, J., Schaad, N. W., Stead, D. E., Surico, G. & Ullrich, M. S. (eds.). Dordrecht: Springer, p. 185-198 14 p.. Research output: Chapter in Book/Report/Conference proceeding › Conference contribution ...
on New Years Eve having covered 2500 km in three weeks training. Speaking to Bild about the 2005 season, Ullrich clearly stated that should Lance Armstrong choose to ride the Tour de France, ?I, like many other riders, want to be the one who unseats him! He went on to add that should he find himself in a similar position to this year where he was forced into a support role for his team mate Andrea Kl?den, he would have no problem with that. ?The best rider will be supported. I have no problem with this policy. I already showed that this year. But I know that when I avoid health setbacks, then I can be the strongest. ...
Zonal changes in the three-dimensional morphology of the chondron under compression: the relationship among cellular, pericellular, and extracellular deformation in articular cartilage ...
Erico VI de Dinamarca (es); VI. Erik dán király (hu); Eiríkur menved (is); Erik VI.a Danimarkakoa (eu); Erik VI de Dinamarca (ca); Erik VI. (de); Эрык VI (be); اریک ششم دانمارک (fa); 埃里克六世 (zh); Erik Menved (da); ერიკ VI (დანია) (ka); エーリク6世 (デンマーク王) (ja); Erik Menved (sv); Ерік VI (король Данії) (uk); Eerik Menved (fi); Eriko la 6-a de Danio (eo); Erik VI. Dánský (cs); Eric VI di Danimarca (it); Éric VI de Danemark (fr); Érico VI da Dinamarca (pt); Erik VI van Denemarke (af); Erik VI van Denemarken (sl); Eric VI of Denmark (en); Érico VI da Dinamarca (pt-br); اريك السادس من الدنمارك (arz); พระเจ้าอีริคที่ 6 แห่งเดนมาร์ก (th); Eryk Menved (pl); Erik Menved (nb); Erik VI van Denemarken (nl); 에리크 6세 (ko); سککیزینجی اریک (azb); אריק השישי, מלך דנמרק (he); Эрик VI (ru); Erik VI de Dinamarca (gl); ...
When I finally put the mouse down and the broadband dust had settled I chose Warp 9 for their color options and overall pricing. Also, I dug the fact their wheel sets come complete with OEM swappable bearings, sprocket (you specify size when ordering), and wave rotors. Ill be honest, there was some apprehension due to previous concerns over Warp 9′s quality although a friend of mine had an issue with their foot pegs and the company promptly sent him a new set at no charge. That eased my mind as far as warranty issues. Nowadays unquestionable good customer service is hard to come by.. Warp 9 experience started with a few questions regarding manufacturing, shipping, warranty etc. I sent Warp 9 a few emails and was promptly responded to. I didnt feel like a sales # and was responded to by a human in the continental U.S. unlike most modern-day customer service.. Ultimately the Warp 9 wheelset has become my permanent (instead of spare) set of wheels and will transfer to my next scooter when the ...
Triangle Orthopaedic Associates helps North Carolina patients suffering from arthritis in their fingers by performing distal join fusions.
Try Wolfram|Alphas warp speed calculator to compute the relationship between warp factors and the speed of light. Different formulas in each series.
Im making separate selvedges out of white rayon and using a supplementary warp (egg plant color) for the punch. The technique for the supplementary warp Ill use is split broche. The threads will not be in the heddles as they are threaded amongst the warp threads which on are 4 shafts. More on this when I get started. For now, you can see those threads on their own small kitestick ...
Við hjá Even labs leggjum okkur fram um að finna tæki og lausnir, sem byggja á vísindalegum rannsóknum. Við leitumst við að halda utan um þessar upplýsingar og birta þær jafnóðum á síðunni eða vísa rannsóknarniðurstöður. Við leggjum áherslu á það við okkar viðskiptvini að þeir taki ábyrgð á eigin heilsu. Að því sögðu, þá mælumst við alltaf með því að fólk, sem er í meðferð hjá lækni eða öðrum fagmanni, hafi samráð við lækni ef viðkomandi tekur endanlega ákvörðun um breytingar á inntöku lyfja eða hyggst fara óhefðbundnar leiðir.. Hér að neðan munum við halda utan um upplýsingar um helstu rannsóknir, sem tengjast þeim meðferðum sem við bjóðum uppá. Við munum birta úrdrætti og lykilniðurstöður hér að neðan ásamt hlekk á viðkomandi rannsókn. Við biðjumst velvirðingar á því, að hluti af þessum upplýsingum eru og verða á ensku.. ...
必应词典为您提供warp的释义,美[wɔrp],英[wɔː(r)p],n. 经纱; v. 弯曲;使(行为等)不合情理;使乖戾; 网络释义: 扭曲;翘曲;变形;
Vi er et effektivt team, som går langt for at servicere vore kunder. Vi tror på de gamle købmandsværdier, og sætter en ære i at være professionelle og troværdige i alt hvad vi gør. Vores størrelse gør at vi kan agere meget fleksibelt, og vi vil gøre alt hvad vi kan for at løse dit problem. Vi giver dig reel rådgivning, og vi sælger ikke halve løsninger ...
VI LÄSER TILLSAMMANS: PYJAMASHJÄLTARNA i Tidningsarkivet. Ett digitalt arkiv för svenska tidningar och tidskrifter. Här finns bland annat omslag och innehållstexter för VI LÄSER TILLSAMMANS: PYJAMASHJÄLTARNA.
Whether youre recovering from surgery, in need of rehab or require long-term nursing care, our dedicated skilled nursing staff is ready to help.
No doubt the prime reason Mithridates took regular antidotes against poisoning is because his mother, Laodice VI, had poisoned his father.
Folkehelse handler om befolkningens helsetilstand og hvordan helsen fordeler seg i en befolkning. Hvilken livsstil vi har, er et resultat av hvilke valgmuligheter vi har og hvilke valg vi gjør… ...
REVIJA O KONJIH sproža svoj metuljev efekt. Ustvarite svoj PublishWall virtualni zid tudi Vi, posredujte različne vrste objav na virtualne zidove prijateljev, lokalnih skupnosti in interesnih skupin. Izkoristite moč povezovanja.