The effect of cold exposure on the systemic renin-angiotensin system and on regulation of the angiotensin II (Ang II) receptor was examined in target organs for Ang II with cardiovascular relevance (left ventricle, kidney, lung) and metabolic relevance [interscapular brown adipose tissue (ISBAT), liver] to the functional consequences of cold exposure. In time course studies, the effects were examined of 4 hr or 1, 3 and 7 days of exposure to cold (4 degrees C) on plasma Ang II concentration and Ang II receptor binding characteristics in rat liver. Plasma Ang II concentration increased 10-fold after 4 hr of cold exposure, returned to control levels at days 1 and 3 of cold exposure, and was again increased (2-fold) at 7 days of cold exposure. The affinity of [125I]Sar1, Ile8-Ang II binding in membranes prepared from rat liver was not altered in cold-exposed rats. The density (Bmax) of binding sites in liver from cold-exposed rats was increased by day 1 and remained elevated over time-matched controls.
by Sze Hang Fu, Peter S. Rodriguez & Prabhat Jha. Extreme temperatures, including cold spells and heat waves, have detrimental effects on human health. Most climate change projections foresee extreme weather becoming more prevalent. Indeed, various parts of the world have already begun to experience the impact of extremely hot weather. Much less attention has been given to the health effects of cold temperature ranges.. To tackle this knowledge gap, a recent Indian study estimated the association between extremely and moderately hot and cold temperatures with human mortality [1]. The study found that while extremely hot temperature had the highest mortality risk, moderately cold temperature contributed to the most deaths in India.. Read the full article here. Comments are closed.. ...
This text introduces the reader to the problem of cold temperature exposure of refugees from the perspective of health risks as well as from the perspective of human rights. The arrival of large numbers of displaced persons in Northern Europe in 2015 and the challenge to provide sufficient shelter in a cold climate serve as the point of departure for the research presented here. Combining these approaches in a literature research of primary and secondary materials, the text shows that a wide range of international treaties can be utilized to argue in favor of a positive obligation for states to provide shelter to displaced persons and protection against cold temperatures. Describing the dangers associated with exposure to cold temperatures and investigating a range of binding legal documents, the authors show that international law can be used to force states to take action to solve a simple but life-threatening problem. Particular emphasis is given to the efforts made by Finland to provide ...
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Background: Temperature and other environmental stressors are known to affect blood pressure and heart rate. The cold pressor test is used clinically to evaluate autonomic and left ventricular functions.. Aims: This project was done to test the hypothesis that blood pressure and heart rate is altered during the cold pressor test.. Methods: Students performed the cold pressor test, to study the change in blood pressure following an environmental stress. 40 medical students from the Ist year MBBS batches were selected and tested for cold pressor test during 1 to 2 min immersion of one hand in ice water. This test used cold as a stressful stimulus. The response of the subject was measured by the change in blood pressure and heart rate after the application of cold stimulus.. Results: The study showed that the correlation between Anxiety state scores and cold pressor test response was not significant statistically. The correlation between Anxiety trait scores and cold pressor test response was also ...
Download Free Full-Text of an article THE EFFECT OF COLD TEMPERATURE ON OXIDATIVE DAMAGE AND ACTIVITY OF OXIDATIVE ENZYMES IN TEA LEAVES FROM NORTHERN IRAN
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When is it too cold for my dog to go outside? Winter has come and some of us are experiencing cold temperatures and snow. This guide helps you and your dog survive the cold temperatures!
Aerospace applications have an increasing demand for strong and reliable adhesives, able to withstand large temperature gradients. The variation of the adhesives mechanical properties with temperature is therefore one of the factors that must be well understood before safe and reliable adhesive joints can be designed for these applications. The stress-strain curve and the toughness properties of an adhesive show strong dependency with temperature for most adhesives, especially near the glass transition temperature (Tg). In this work, an experimental procedure is undertaken to evaluate the effect of low temperatures on the adhesive strength and mode I fracture toughness of a room temperature vulcanizing silicone (RTV) adhesive. Firstly, the temperature at which the glass transition of the RTV occurs was obtained by means of an in-house developed measurement apparatus. Bulk specimens were manufactured and tested at temperatures above and below the Tg in order to obtain a strength envelope of the ...
The present study evaluates the effect of dietary ascorbic acid and chromium (AACr) on performance and microflora balance of broiler reared under thermoneutral conditions (TN) vs. high heat stress (HS). Two experiments were conducted on 112 Cobb 500 broilers, assigned in two experimental groups (28 chickens/group) and housed in an environmental controlled hall. Two groups (C-TN and AACr-TN) were kept in thermoneutral conditions. In the second experiment, other two groups were kept (C-HS and AACr-HS) in high heat stress (32° C). The structure of diets was the same in both experiments. Compared with the control diet (C), the experimental diet included the addition of a premix with 25 g ascorbic acid / kg premix + 20 mg chromium picolinate/ kg premix (AACr). At the end of the experiment, 8 broilers / group were slaughtered and samples of intestinal and caecal content were collected for bacteriological assessment. Dietary AACr did not affect (p,0.05) body weight, daily feed intake, feed conversion ...
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February 13, 2013. Scientists at the University of Southern California have found a way to turn off the neuron responsible for sensing cold in mice, and it could help humans who have extreme sensitivities to cold temperatures.. The neuron channel, called TRPM8, is responsible for sensing normal cold responses in mammals, according to David McKenny, the neurobiologist responsible for the study, which was published in the Journal of Neuroscience Tuesday. By turning it off in mice, the animals turned insensitive to cool and painfully cold temperatures and did not distinguish between cold and a preferred warm temperature. The mice were still able to feel warm temperatures and pain.. Though the process is currently irreversible, McKenny says if pharmaceutical companies can develop a drug that will make the effect temporary, it could be useful for patients with certain conditions that make them hypersensitive to cold temperatures.. Read more ...
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When bitterly cold temperatures hit, you have to be careful to avoid staying out in the frigid air for too long. A cold weather emergency can happen relatively
Getting a pre-existing heart problem can place you at elevated risk for severe heart disease. Cold temperature and cardiovascular disease frequently dont mix well, however this doesnt mean you need to lose out on winter fun. By being conscious of the following advice and heart risks that cold temperature makes you to face, you may make better decisions regarding how to spend these cooler several weeks.. Cold temperature can narrow bloodstream vessels: This can be a response from the body so that they can retain heat, but regrettably, it can possibly put more force on the center while increasing bloodstream pressure and heartbeat. Its suggested to remain inside during very cold temperature.. Cold air may cause chest discomfort: This might take place in a lot of people. Putting on a shawl might help mitigate this as it can certainly warm-up the environment before you decide to breathe it.. Watch out for influenza: The cooler several weeks frequently bring by using it influenza along with other ...
SAN ANGELO, TX - Bitterly cold temperatures are forecast for San Angelo and the Concho Valley Monday and Tuesday nights as a strong, dry cold front blows through the region. According to the National Weather Service, temperatures will remain below usual mid December temperatures tonight and Tuesday. Lows tonight will be in the 20s, and highs on Tuesday will be mainly in the 45
In Experiment 1 ascites related mortality was 6%, 0%, 16% and 19% after 1, 2, 3, and 4 weeks of cold exposure (100 C), respectively. After 4 weeks of cold exposure ascites related mortality was 24% in verapamil supplemented cold exposed broilers, in comparison to a 35% mortality in non- supplemented cold exposed broilers. Body weight was significantly depressed by cold exposure. Hematocrit was significantly elevated by cold exposure. Verapamil decreased hematocrit only in the ascitic cold-exposed population. RV/TV, RV/LV ratios were significantly increased by cold exposure in the ascitic population. Verapamil had no apparent effect on these variables. The ECG analysis employed accurately reflected the right ventricular hypertrophy observed by invasive measures. Right ventricular calcium, but not left, was significantly increased by cold exposure. verapamil non- significantly decreased calcium accumulation to control levels. In Experiment 2, there was a 0%, 4.3%, and 26% ascites related mortality ...
The City of St. Louis Department of Health is urging residents to prepare for an extended period of extreme cold temperatures and the first accumulating snow of the season
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Were in the midst of bitter cold temperatures that will stay in the area over the next few days. How cold will it be? Take a look at our gallery.
Global High Pressure Cold Water Cleaners Market Report illustrates the present development status of High Pressure Cold Water Cleaners along with the growth of High Pressure Cold Water Cleaners expected during the forecast period during 2017-2022. High Pressure Cold Water Cleaners Market analyses the industry based on different factors like growth trends, consumer volume, High Pressure Cold Water Cleaners market size and demand and supply status. High Pressure Cold Water Cleaners Market is a beneficial research material which conducts a competitive analysis of the High Pressure Cold Water Cleaners market. This report also portrays the High Pressure Cold Water Cleaners industry structure based on the product cost, major industry players, product applications, import/export details and High Pressure Cold Water Cleaners market competition.. A complete study of High Pressure Cold Water Cleaners based on emerging and dominant market segments, major geographical regions, supply chain analysis, High ...
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Life threatening cold temperatures and icy weather conditions have hit the Midwest and the Northeast United States this weekend.
Youngsters recently learned all about the science of cold temperatures in Boca Raton. The Childrens Science Explorium at Sugar Sand Parks community center offered a one-week Winter Break Blast
A recent study published in the journal Cell Metabolism found that 12-HEPE, a lipid produced by the body in response to cold temperatures, may help reduce blood sugar levels. Researchers from Brazil, the U.S. and Germany conducted a series of experiments on mice and humans and found that it could help shuttle glucose into tissues and improve glucose tolerance […]
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Using hot or cold temperatures to change the size of your pores is unfortunately a home remedy trick. There is no way to change the size of your pores.
The Sparta Area School District will be CLOSED today, February 14th, due to very cold temperatures. Evening activities to proceed as planned ...
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To determine (1) whether acclimation of carbon metabolism to low temperatures results in recovery of the relative growth rate (RGR) of plants in the cold and (2) the source of N underpinning cold-acclimation in Arabidopsis thaliana, we supplied plants with a nutrient solution labelled with 15N and subjected them to a temperature shift (23oC to 5oC). Whole-plant RGR of cold-treated plants was initially less than 30% of that of warm-maintained control plants. After 14 days, new leaves with a cold-acclimated phenotype emerged, with the RGR of cold-treated plants increasing by 50%; there was an associated recovery of root RGR and doubling of the net assimilation rate (NAR). The development of new tissues in the cold was supported initially by re-allocation of internal sources of N. In the longer-term, the majority (80%) of N in new leaves was derived from the external solution. Hence, both the nutrient status of the plant and the current availability of N from external sources are important in ...
The CBF regulon has a major role in freezing tolerance. The initial evidence for this was the finding that transgenic Arabidopsis plants constitutively expressing CBF1, CBF2, or CBF3 resulted in an increase in freezing tolerance without exposing plants to low temperature (Jaglo-Ottosen et al., 1998; Liu et al., 1998; Gilmour et al., 2004). Subsequently, Novillo et al. (2007) used RNA interference and antisense constructs to down-regulate the expression of CBF1 and CBF3 and found that this resulted in about a 25% to 50% decrease in freezing tolerance in cold-treated plants. In addition, Hannah et al. (2006) examined six accessions of Arabidopsis that differed in freezing tolerance and found that the levels of CBF1 and CBF2 expression, as well as genes that constitute the CBF2 regulon, positively correlated with freezing tolerance. Finally, Alonso-Blanco et al. (2005) mapped quantitative trait loci (QTLs) for freezing tolerance in recombinant inbreed lines produced from a cross between two ...
Boiling water does evaporate at cold temperatures. At the boiling point (212 degrees F), water will evaporate at a much faster rate because it loses heat energy quicker than cold energy. As the boiling water begins to cool, the process of evaporation is still present, but at a slower rate.Source:U.S. Geological Survey: The Water Cycle - EvaporationUSAToday: Molecular Motion Determines Water's StateCool Physics Phenomena: Hot Water Freezes Faster Than Cold
TY - JOUR. T1 - Interferon regulatory factor 8 expressed in microglia contributes to tactile allodynia induced by repeated cold stress in rodents. AU - Akagi, Takanori. AU - Matsumura, Yuta. AU - Yasui, Masaya. AU - Minami, Emiko. AU - Inoue, Hidemasa. AU - Masuda, Takahiro. AU - Tozaki-Saitoh, Hidetoshi. AU - Tamura, Tomohiko. AU - Mizumura, Kazue. AU - Tsuda, Makoto. AU - Kiyama, Hiroshi. AU - Inoue, Kazuhide. N1 - Publisher Copyright: © The Japanese Pharmacological Society. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.. PY - 2014. Y1 - 2014. N2 - We investigated the role of interferon regulatory factor 8 (IRF8) in a model of chronic pain in which repeated cold stress (RCS) exposure produces tactile allodynia. RCS exposure produced a decrease in paw withdrawal threshold (PWT) to mechanical stimulation. Spinal microglia of RCS-exposed mice were morphologically activated. Expression of IRF8 was significantly increased in the spinal cord of RCS-exposed mice and was localized in ...
TY - JOUR. T1 - Effect of diet and cold exposure on norepinephrine turnover in pancreas and liver. AU - Young, J. B.. AU - Landsberg, L.. PY - 1979/1/1. Y1 - 1979/1/1. N2 - The potential contribution of the sympathetic nervous system to the regulation of the endocrine pancreas and the liver has previously been studied only in vitro or by indirect in vivo methods. This report describes the adaptation of the [3H]norepinephrine ([3H]NE) turnover technique to rat pancreas and liver as well as the application of this technique to the evaluation of sympathetic activity in these organs during cold exposure, fasting, and overfeeding. Cold exposure (4°C) increased the calculated pancreatic NE turnover rate 83% from 16.6 ± 1.1 ng NE/organ per hr to 30.4 ± 1.9 (95% confidence intervals), whereas hepatic NE turnover rate increased only 25% from 47.0 ± 3.4 to 58.7 ± 3.3. Two days of fasting reduced pancreatic NE turnover rate 70% from 26.8 ± 3.0 ng NE/organ per hr to 8.0 ± 0.8, whereas hepatic NE ...
The effects of cold acclimation (CA) on the cardiorespiratory responses to cold air and water stress tests (CST) were studied in seven males before and after a CA program of daily 90 min cold water (18 C) immersions repeated five times a week for five consecutive weeks. The CST consisted of a 90 min resting exposure to cold air or water during which rectal temperature (T sub re), oxygen consumption (VO2), carbon dioxide production (VCO2), minute ventilation (V sub E), heart rate (HR), cardiac output (Q) and blood pressure (BP) were periodically measured. In cold air following CA, the VO2 at 10 minutes was lower post than pre CA, however, no differences were found in cold water. The (V sub E) increased during CST as a function of VCO2. The CA did not affect the (V sub E)-VCO2 relationship or the pattern of breathing during CST in cold air or water. The CA had no effect on Q or (a-V) O2 difference, which both increased during the first 45 min of CST, then remained stable. BP increased significantly during
US - Extreme cold temperatures impacted livestock movements throughout the this week, impacting cattle and hog slaughter, write Steve Meyer and Len Steiner.
TY - JOUR. T1 - Brown adipose tissue derived VEGF-A modulates cold tolerance and energy expenditure. AU - Sun, Kai. AU - Kusminski, Christine M.. AU - Luby-Phelps, Kate. AU - Spurgin, Stephen B.. AU - An, Yu A.. AU - Wang, Qiong A.. AU - Holland, William L.. AU - Scherer, Philipp E.. PY - 2014. Y1 - 2014. N2 - We recently reported that local overexpression of VEGF-A in white adipose tissue (WAT) protects against diet-induced obesity and metabolic dysfunction. The observation that VEGF-A induces a brown adipose tissue (BAT)-like phenotype in WAT prompted us to further explore the direct function of VEGF-A in BAT. We utilized a doxycycline (Dox)-inducible, brown adipocyte-specific VEGF-A transgenic overexpression model to assess direct effects of VEGF-A in BAT invivo. We observed that BAT-specific VEGF-A expression increases vascularization and up-regulates expression of both UCP1 and PGC-1α in BAT. As a result, the transgenic mice show increased thermogenesis during chronic cold exposure. In ...
Workers who cut, shape, place and install conduit and wire trays in cold environments face hazards from cold-related injuries and illnesses including slipping and falling, hypothermia, and frostbite. Working in cold temperatures, especially with wind and moist clothing, poses a serious threat to a worker’s health. Prolonged periods of exposure to harsh conditions can result in injuries, usually starting with a worker’s extremities.
Workers who install pipe assemblies, fittings, valves, appliances and fixtures in cold environments face hazards from cold-related injuries and illnesses including slipping and falling, hypothermia, and frostbite. Working in cold temperatures, especially with wind and moist clothing, poses a serious threat to a worker’s health. Prolonged periods of exposure to harsh conditions can result in injuries, usually starting with a worker’s extremities.
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TY - JOUR. T1 - Metabolic regulatory network alterations in response to acute cold stress and ginsenoside intervention. AU - Wang, Xiaoyan. AU - Su, Mingming. AU - Qiu, Yunping. AU - Ni, Yan. AU - Zhao, Tie. AU - Zhou, Mingmei. AU - Zhao, Aihua. AU - Yang, Shengli. AU - Zhao, Liping. AU - Jia, Wei. N1 - Copyright: Copyright 2008 Elsevier B.V., All rights reserved.. PY - 2007/9. Y1 - 2007/9. N2 - Acute stress may trigger systemic biochemical and physiological changes in living organisms, leading to a rapid loss of homeostasis, which can be gradually reinstated by self-regulatory mechanisms and/or drug intervention strategy. However, such a sophisticated metabolic regulatory process has so far been poorly understood, especially from a holistic view. Urinary metabolite profiling of Sprague-Dawley rats exposed to cold temperature (-10°C) for 2 h using GC/MS in conjunction with modern multivariate statistical techniques revealed drastic biochemical changes as evidenced by fluctuations of urinary ...
Cold acclimation and exercise training were previously shown to increase peripheral insulin sensitivity in human volunteers with type 2 diabetes. Although cold is a potent activator of brown adipose tissue, the increase in peripheral insulin sensitivity by cold is largely mediated by events occurring in skeletal muscle and at least partly involves GLUT4 translocation, as is also observed for exercise training. To investigate if cold acclimation and exercise training overlap in the molecular adaptive response in skeletal muscle, we performed transcriptomics analysis on vastus lateralis muscle collected from human subjects before and after 10 days of cold acclimation, as well as before and after a 12-week exercise training intervention. Cold acclimation altered the expression of 756 genes (422 up, 334 down, P | 0.01), while exercise training altered the expression of 665 genes (444 up, 221 down, P | 0.01). Principal Component Analysis, Venn diagram, similarity analysis and Rank-rank Hypergeometric Overlap
TY - JOUR. T1 - Cold exposure down-regulates adiponutrin/PNPLA3 mRNA expression and affects its nutritional regulation in adipose tissues of lean and obese Zucker rats.. AU - Oliver, Paula. AU - Caimari, Antoni. AU - Diaz Rua, Ruben. AU - Palou, Andreu. PY - 2012/1/1. Y1 - 2012/1/1. N2 - Adiponutrin/PNPLA3 is a protein highly produced in adipose tissue whose expression is under tight nutritional regulation. It possesses lipogenic/lipolytic capacity and, although adiponutrin polymorphisms are related to obesity, its physiological role is not clear. To help clarify its role, we studied the effect of acute cold exposure on adiponutrin mRNA expression in different adipose tissues of lean/obese Zucker rats subjected to feeding/fasting/refeeding. The effect of cold on the expression of key lipogenic enzymes and on uncoupling protein-1 (UCP1) was evaluated in selected adipose depots. Adiponutrin mRNA levels were also determined in the adipose tissue of isoprenaline-treated rats and in cultured ...
Predation by the sand shrimp has been implicated as one of the most significant sources of mortality for recently hatched metamorphosed winter flounder. Experiments conducted by Taylor and Collie found that shrimp consumption rates on post-settlement flounder significantly increased with increasing flounder density, irrespective of water temperature. At low flounder densities, however, significantly more flounder were consumed at warm temperatures than at cold temperatures (16 °C and 10 °C, respectively, or 61 °F and 50 °F). Model estimates and visual observations of shrimp foraging behavior suggest that the variable feeding rates at different temperatures are the result of cold temperatures decreasing predator activity at low flounder densities, and conversely, shrimp maintaining high predation rates at low flounder densities when exposed to warm temperatures. These findings indicate that shrimp are capable of driving flounder populations to local extinction during warm water conditions ...
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The cold shock domain (CSD) is a nucleic acid binding domain that is widely conserved from bacteria to higher plants and animals. In Escherichia coli, cold shock proteins (CSPs) are composed solely of a CSD and function as RNA chaperones that destabilize RNA secondary structures. Cellular RNAs tend to be folded into unfavorable structures under low temperature conditions, and RNA chaperones resolve these structures, recovering functionality of the RNAs. CSP functions are associated mainly with cold adaptation, but they are also involved in other biological processes under normal growth conditions. Eukaryotic CSD proteins contain auxiliary domains in addition to the CSD and regulate many biological processes such as development and stress tolerance. In plants, it has been demonstrated that CSD proteins play essential roles in acquiring freezing tolerance. In addition, it has been suggested that some plant CSD proteins regulate embryo development, flowering time, and fruit development. In this review, we
CLEVELAND -- Extremely cold temperatures are returning to northeast Ohio this week. RTA will be keeping several of our enclosed passenger facilities and transit centers open all night for three nights beginning Tuesday evening, January 29 through Thursday night.
I have a small dry cabin and its plumbed for propane lights. Im installing a small range and gas fridge and, in my research, Ive discovered I may have a problem with my design. First, Ill be using two 40# tanks for ease of transportation. In addition to the range and fridge I have a total of 8 Mr. Heater lights. What are some of everyones experiences with using propane in cold temperatures? Im concerned the pressure in my tanks will drop and some of my appliances will be
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11th October 2019 Recent independent UKAS accredited testing has proven that UltraCrete rapid strength bedding mortar, M60, can outperform its key competitor at temperatures as low as 5°C.. Launched over 30 years ago, UltraCrete M60 is the market leading bedding mortar. Recent independent UKAS testing demonstrated that it still consistently delivers, reporting that the rapid strength bedding mortar has been proven to be 83% stronger than other similar products at 5°C, making it the go to rapid bedding mortar for the winter months. Additionally M60 also achieves an impressive 20N/mm² in just 45mins at 20°C.. UltraCrete M60 is dimensionally stable in wet weather and low temperatures, with no cracking or surface crazing. It can be used for all access covers, as well as for the bonding of granite setts, flags and bedding kerbs. HAPAS (Highways Authority Product Approval Scheme) approved since 2005, M60 also conforms to the required standard of HD27/15 (Design Manual for Roads and Bridges) ...
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With cold temperatures descending around the country, the American Red Cross has come out with tips focused on keeping citizens safe
Environmental temperature influences energy intake utilization and tissue deposition in pig. However, physiological mechanisms involved in muscle metabolic adaptation to cold temperature are unclear. This study aimed at evaluating the effects of a cold temperature applied during the post-weaning (PW) and growing-finishing (GF) periods of pigs on growth performance, body composition and Longissimus muscle (LM) energy metabolism, with emphasis on the AMP-protein kinase (AMPK) pathway involved in homeostasis regulation. A total of 84 Large White x (Large White x Landrace) piglets (castrated males and females) fed ad libitum were submitted to either Cold (C: from 23°C to 15°C) or Thermoneutrality (T: from 28°C to 23°C) temperature during PW. 12 C and 12 T piglets were slaughtered at 25 kg and the remaining piglets were reared at 12°C (CC) or 23°C (TT), up to 115 kg. During PW, cold exposure induced strong responses on growth performance. Despite a higher average feed intake (AFI, + 50 g/d, P|0.01), C
Larvae and adults of A. aegypti are clearly capable of cold acclimation when presented with a change in larval or adult acclimation temperature. In the present study, we compared the effects of development or adult acclimation at only two temperatures (15 and 25°C), but demonstrate that this difference of 10°C was sufficient to substantially alter chill tolerance in this important vector of disease. Cold-acclimated larvae and adults more rapidly recovered from chill coma following cold stress, and had significantly higher survival following chronic cold. After 12-16 h at 2°C, very few larvae acclimated to 15°C showed any signs of chilling injury while ∼30% of larvae acclimated to 25°C were clearly suffering from neuromuscular injury that prevented them moving in a coordinated manner (Fig. 2B).. Chilling injury has been repeatedly associated with a systemic loss of ion balance in several terrestrial insects, including members of Hemiptera, Diptera, Blattodea, Lepidoptera and Orthoptera ...
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Stay hydrated and well fuelled: In severe cold, extra calories are required just to function let alone race. Make sure your system is topped up on energy and not starting at a disadvantage. As race delays are common in severe cold, bring enough food to continue eating during delay periods. This could involve eating a pre-race breakfast as normal but also packing a pre-race lunch in the case of a long delay (also smart to do if avalanche control delays are possible). Cold temperatures are definitely a good time to use a carbohydrate replacement like Hammer HEED. Any extra calories you can take in will be useful and warm HEED will do the trick.. Exercise-induced bronchoconstriction (EIB) is also common in ski mountaineers. High breathing frequency and frigid temperatures at altitude cause airway obstruction in 50% of racers elite racers, the majority of whom are unaware. EIB can significantly impact performance and should be discussed with a physician if an athlete has any history of asthma or ...
The effects of peripheral cold exposure on myocardial perfusion and function were studied in 13 patients with scleroderma without clinically evident myocardial disease. Ten patients had at least one transient, cold-induced, myocardial perfusion defect visualized by thallium-201 scintigraphy, and 12 had reversible, cold-induced, segmental left ventricular hypokinesis by two-dimensional echocardiography. The 10 patients with transient perfusion defects all had anatomically corresponding ventricular wall motion abnormalities. No one in either of two control groups (9 normal volunteers and 7 patients with chest pain and normal coronary arteriograms) had cold-induced abnormalities. This study is the first to show the simultaneous occurrence of cold-induced abnormalities in myocardial perfusion and function in patients with scleroderma. The results suggest that cold exposure in such patients may elicit transient reflex coronary vasoconstriction resulting in reversible myocardial ischemia and ...
Environmental stress generally disturbs cellular homeostasis. Researchers have hypothesized that chilling injury is linked to a shortage of ATP. However, previous studies conducted on insects exposed to nonfreezing low temperatures presented conflicting results. In this study, we investigated the mitochondrial bioenergetics of Drosophila melanogaster flies exposed to chronic cold stress (4 °C). We assessed mitochondrial oxygen consumption while monitoring the rate of ATP synthesis at various times (0, 1, 2, and 3 days) during prolonged cold stress and at two assay temperatures (25 and 4 °C). We compared organelle responses between cold-susceptible and cold-acclimated phenotypes. Continuous exposure to low temperature provoked temporal declines in the rates of mitochondrial respiration and ATP synthesis. Respiratory control ratios (RCRs) suggested that mitochondria were not critically uncoupled. Nevertheless, after 3 days of continuous cold stress, a sharp decline in the mitochondrial ATP synthesis
Another idea is to put a tarp over the house or a towel to work as a doorway, so the inside doest get wet. Another important thing for pet owners to remember, is that just because it is cold, you still have to give your animal water. Water may freeze easily, so it is best to use a plastic bowl, and check the water often to make sure it has not turned to ice. Brown and Maynes told NBC 26 Monday, that during these cold conditions animals need extra calories to sustain the energy to fight the chill, so it is always best to give your pet extra food. Neglecting to care for your pet in weather conditions is against the law, and fines can be hefty. Mayne at the Columbia Animal Control, said they already have had a few dogs brought in because of the extreme weather conditions, and they are investigating those cases now. Mayne said that with this cold weather, they are keeping a close eye on pets in the area, and urge people to report any pets left outside without proper shelter and food to the Animal ...
There are proven acute regenerative benefits of both cold water immersion and cold application after exercise... cool? Not so cool, no. Two recent studies demonstrate: In the long run both will impair your gains.
Symptoms of hypothermia include shivering, slurred speech, slow breathing, lack of coordination and confusion. Age factor and your tolerance levels play a role in how your body responds to the outer environment. For children, a fever is when their body temperature is more than 100.4°F (measured rectally), 99.5°F (measured orally) or 99°F (measured under the arm). Conditions that can cause hypothermia include: 11 Common signs and symptoms of hypothermia include: Not everybody who is exposed to the cold develops hypothermia. If your core body temperature dips down to 95 F (35 C) or lower, thats considered hypothermia. For adults, a fever is when the body temperature is higher than 100.4°F. Core body temperature is normally 37°C, no matter what the temperature of the surroundings or the activity level of the individual. The normal body temperature can be anywhere between 97°F (36.1°C) and 99°F (37.2°C) in different individuals. HSE does not have specific guidance for working in cold ...
Two-component systems (TCS) allow a cell to elaborate a variety of adaptive responses to environment changes. The recently discovered CasK/R TCS plays a role in the optimal unsaturation of fatty acids necessary for cold adaptation of the foodborne-pathogen Bacillus cereus. Here, we showed that the promoter activity of the operon encoding this TCS was repressed during growth at low temperature in the stationary phase in the parental strain when compared to the casK/R mutant, suggesting that CasR negatively regulates the activity of its own promoter in these conditions. The promoter activity of the desA gene encoding the delta-5 fatty acid desaturase, providing unsaturated fatty acids (UFAs) required for low temperature adaptation, was repressed in the casK/R mutant grown at 12°C versus 37°C. This result suggests that CasK/R activates desA expression during B. cereus growth at low temperature, allowing an optimal unsaturation of the fatty acids. In contrast, desA expression was repressed during the lag
Raynauds Syndrome. Raynauds phenomenon. Raynauds disease. Cold hands? Cold fingers? Cold feet? Cold toes? The Haven Healing Centre. Complementary Therapy in Bristol, Bath and Surrounding Area. Philip Chave, Healer and Therapist
TY - JOUR. T1 - Skin temperature and photoelectric plethysmography recovery characteristics during mild cold challenge testing in normal subjects. AU - Allen, John. AU - Montague, C. AU - Murray, A. PY - 1999/12/1. Y1 - 1999/12/1. M3 - Conference article. VL - 36. SP - 327. JO - Journal of Vascular Research. JF - Journal of Vascular Research. ER - ...
Chemical Engineering Grain Processing Seminar Series Xue Mi Department of Chemical Engineering Michigan Technological University Advisor: Dr. Caryn Heldt Abstract: Viral diseases continue to take the lives of millions of people each year. The most effective method to prevent viral infection is with vaccines. In order for viral vaccines to be effective they must be transported and stored at cold temperatures. If temperatures are not maintained, the vaccine may lose its potency and could no longer be effective in fighting disease. This is called the cold storage problem. Finding a way to thermally stabilize a virus so a vaccine does not need to be transported and stored in cold temperatures is important to the health and safety of many people. We are exploring the use of polyelectrolyte dense phases to stabilize viruses. But to reduce the need to randomly screen different polyelectrolytes, we have chosen to first explore viral surface properties. The property we have focused on is virus surface
TY - JOUR. T1 - The cold pressor test during radionuclide ventriculography. T2 - A feasibility study in cancer patients. AU - Verwey, J.. AU - Van Lingen, A.. AU - Teule, J. J.. AU - Heidendal, G. A K. AU - Pinedo, H. M.. PY - 1986/3. Y1 - 1986/3. N2 - To monitor the use of cardiotoxic drugs, adequate assessment of myocardial function is required. Although serial radionuclide left ventricular ejection fraction (EF) studies allow a simple and rapid assessment of the myocardial function without risk or discomfort to the patient, they appear not to be sensitive enough. Determination of the EF during cold application may be more sensitive. In this study we tested the feasibility of the cold pressor test (CPT) in relation to EF determination in 23 cancer patients. Only minor side effects were recorded. The response of heart rate to cold was similar to the response reported in healthy volunteers and patients with coronary artery disease. In selected cases EF determination during CPT appeared to be ...
THERAFLU WARMING RELIEF NIGHTTIME SEVERE COLD & COUGH (Diphenhydramine,Phenylephrine,Acetaminophen) drug information & product resources from MPR including dosage information, educational materials, & patient assistance.
THERAFLU DAYTIME SEVERE COLD & COUGH (Acetaminophen,Phenylephrine,Dextromethorphan) drug information & product resources from MPR including dosage information, educational materials, & patient assistance.
Before having any laboratory performance test, tell your doctor and the laboratory personnel that you are taking Flu & severe cold night time and Pheniramine. Carbetapentane binds Pheniramine and should be given early. Metaxalone has been used for premedication in intubated children, and Carbetapentane is commonly used as an antiemetic in the preoperati
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Comprehensive alcohol & food interactions for Mucinex Fast-Max Severe Cold (acetaminophen / dextromethorphan / guaifenesin / phenylephrine).
Neptune is the coldest planet in the Solar System, maintaining a fairly consistent average of -200 degrees Celsius. Towards the planets equator, temperatures can get as cold as -218 degrees Celsius,...
Transverse oscillations of a microsphere in liquid helium below 0.3 K are investigated. For small amplitudes we observe ballistic drag by phonons and3He impurities. At a threshold velocity amplitude the drag force increases discontinuously to a value determined by turbulence in the superfluid and varies with the square of the velocity amplitude. The turbulent drag coefficient is determined by the density of the liquid and the radius of the sphere, similar to the case of uniform motion in a classical liquid. The threshold velocity for the onset of turbulent friction is found to be independent of the temperature. ...
Cold Temperatures. Cold weather may help some germs prosper. Research from the National Institute of Health suggests that in cold temperatures, flu viruses are more stable; the outer shell of flu virus particles get tougher and more hardy so they survive longer. Low humidity also helps the virus particles remain in the air because the viruses float in the air in small respiratory droplets. When the air is humid, those droplets pick up water, grow larger and fall to the ground.. The cold air also makes it harder for the hairs and mucus in our noses to protect us from germs. The dryness can thicken the mucus and clog the cilia that sweep mucus from our nasal cavity into the back of the throat.. Some research suggests that both the cold air from outdoors as well as the dry air from indoors may play a role in protecting the aerosol droplets we sneeze and cough into the air, allowing them to spread more easily from one sick person to another. Add to that the confined spaces with air heating systems ...
Cold Temperatures. Cold weather may help some germs prosper. Research from the National Institute of Health suggests that in cold temperatures, flu viruses are more stable; the outer shell of flu virus particles get tougher and more hardy so they survive longer. Low humidity also helps the virus particles remain in the air because the viruses float in the air in small respiratory droplets. When the air is humid, those droplets pick up water, grow larger and fall to the ground.. The cold air also makes it harder for the hairs and mucus in our noses to protect us from germs. The dryness can thicken the mucus and clog the cilia that sweep mucus from our nasal cavity into the back of the throat.. Some research suggests that both the cold air from outdoors as well as the dry air from indoors may play a role in protecting the aerosol droplets we sneeze and cough into the air, allowing them to spread more easily from one sick person to another. Add to that the confined spaces with air heating systems ...
Hypothermia and frostbite are serious medical conditions caused by prolonged exposure to cold temperatures. Hypothermia results when the body loses heat faster than it can be produced. The resulting loss in body temperature can affect brain function decreasing the ability to think clearly and move well. Warning signs of hypothermia include a temperature less than 95°, shivering, exhaustion, confusion, fumbling hands, memory loss, slurred speech and drowsiness. Frostbite is an injury to the body caused by freezing. The damage can be permanent and can result in amputation. Frostbite most often affects the nose, ears, cheeks, chin, fingers and toes. The risk of frostbite is increased in people with reduced circulation and individuals not dressed properly for extreme cold temperatures. Signs of frostbite include white or grayish-yellow skin, skin that feels unusually firm or waxy, and numbness. Victims of frostbite and hypothermia require immediate medical attention ...