It has been estimated that over one third of subjects with AN are affected by peripheral neuropathies [6]. In addition, optic neuropathies and other CNS disorders have been found in association with AN (non-isolated AN, Table 1). In this group of subjects the hearing disorder is underlain by several genetic defects, all resulting in neuronal loss and demyelination in peripheral and/or cranial nerves, and the site of the lesion is invariably postsynaptic.. AN has been identified at relatively high frequency in patients affected by Charcot-Marie-Tooth (CMT) disease. The first gene associated with AN in this group was the myelin protein zero (MPZ) gene [24] encoding a protein included in the compact myelin that plays a crucial role in myelin formation and adhesion. A missense mutation in MPZ was identified in a family affected by dominant AN and demyelinating sensorimotor neuropathy [24]. Post-mortem examination carried out on one member of this family revealed preserved hair cells in the cochlea, ...
Assessments of CAP amplitude (Fig. 2) and intraaxonal dye diffusion (Fig. 3) show that direct application of PEG to crush-severed sciatic nerves usually (97% of all attempts) rapidly restores physiological and morphological continuity to at least some axons in the sciatic nerve. In fact, continuity may be restored to many proximal and distal axonal halves (with unknown specificity) since CAP amplitudes of PEG-fused nerves on average are 50 to 89% of CAP amplitudes of intact-control or sham-operated nerves. FF asymmetry scores (Fig. 4) provide quantitative assessment of hindlimb motor behavior and show significantly faster recovery of functional behavior associated with direct application of PEG to crush-severed sciatic nerves. This finding for FF asymmetry scores is consistent with our measures of physiological and morphological continuity.. Video observations of FF trials and of open field trials also show rapid behavioral improvement associated with direct application of PEG to crush-severed ...
http://www.nydailynews.com/news/national/earbud-increases-hidden-hearing-loss-risk-study-article-1.2230945 http://sciencedaily.com/releases/2014/05/140507142804.htm Researchers at Harvard Medical Schools Eaton Peabody Laboratory learned you can lose up to 90 percent of your cochlear nerve fibers from frequent earbud use. Now hear this: Earbud headphones, even at low volume, may be causing permanent damage to your hearing. For decades, scientists have looked, almost exclusively, at the loss of…
Many cephalopods have lines of ciliated cells on their head and arms. In the cuttlefish Sepia and the squid Lolliguncula, electrophysiological recordings clearly identify these epidermal lines as an...
A string instrument pickup system sensitive to 360 of transverse string movement, which is substantially immune from microphonics, and which has a substantially equal or balanced response to all of the strings. In one form of the invention a piezoelectric transducer is compressively associated with vertical movement components of each string of the instrument, but is laterally offset from a centered position under the string for compressive association of the transducer also with the horizontal string movement components; and halves of the total piezoelectric transducer area are oppositely polarized so as to cancel out microphonics. In a modular form of the invention a plurality of the piezoelectric transducers are supported in an elongated array by means of a flexible body of electrically insulative material and a pliable outer wrapping of metal foil so that the transducer is conformable to distortions and deformations in string saddle and bridge elements of the instrument between which the modular
Mice homozygous for the jerker spontaneous mutation (|i|Espn|sup|je|/sup||/i|) show behavior typical of the circling mutants - head-tossing, circling, and hyperactivity. Homozygous mutant mice are deaf from birth and have no detectable stimulus-related cochlear potential at any stage. The abnormal behavior and deafness are associated with postnatal degeneration of the sensory cells of the cochlea and the sacculus and utriculus in homozygotes. The primary influence of the jerker gene appears to be on the apical hair cells, not development of neural structures. Heterozygous jerker mice undergo a similar type of degeneration, but the onset is delayed. Auditory brainstem response is totally absent in homozygotes while heterozygous mice undergo a progressive impairment with age.|br||br|Flexed tail homozygotes can be identified hematologically as earlyas embryonic day 13 and are detectably paler than normal by embryonic day 16, with most paler than normal by embryonic day 15. Homozygotes are small at birth
Canton has recently introduced eight new loudspeakers in its Ergo line, including a new powered subwoofer and seven full-range models featuring new crossover. New models include a trio of three-way floorstanders, two bookshelf speakers, two 2-1/2-way center channel speakers, and a 200-Watt powered subwoofer, and all are available in silver lacquer, black, beech, and cherry wood veneer finishes. The new Ergo full-range models incorporate improved crossover networks that are based on technology developed for the companys signature Karat Reference 2 DC loudspeaker system. These changes include the use of ICW polypropylene capacitors, which have led to a marked reduction in dielectric absorption or "memory" effects giving the models improved transient response and detail. The new crossover design also has a significant reduction in microphonics designed to improve mid-range and high-frequency reproduction. The new Ergo center channel speakers are 2-1/2-way designs optimized for horizontal mounting. ...
Subject: biophysics of infrasound From: Eliot Handelman ,eliot(at)SUNRISE.CC.MCGILL.CA, Date: Thu, 27 Jan 1994 17:19:34 EST Greetings, Im trying to locate research on the biophysical effects of infrasound. A few years ago I collected a series of citations -- about 25? from JASA, primarily from the late 50s and early 60s. Princeton cataloged several of these but they were all missing. It turned out that these papers were reclassified during 80s, and my efforts to get them through the DoD met with no success, supposedly because Princeton did not wish to comply with Dods restricted materials protocol. Can anyone tell me what is so interesting about biophysical effects of infrasound that merits classification? Best, -- eliot ...
... Dehiscences of labyrinthine structures are mainly defects of the semicircular canals. ..
Starting in 2011, infrasound sensors became a standard component and were installed at each new USArray Transportable Array (TA) site. Currently, with over 400 sensors, TA acts as a large infrasound array that continuously samples the wavefield of atmospheric acoustic sources. To support this new data set, the IRIS Data Management Center (DMC) has developed two infrasound data products: the TA Infrasound Reference Event Database (TAIRED) and TA Infrasound Detections (TAID). These two data products are designed to provide insight and tools for researchers to begin working with this large, and somewhat unique, new data set.. TAIRED (http://www.iris.edu/spud/infrasoundevent) is a user-supported evolving infrasound reference event depository where researchers can contribute to and find infrasound events for their research. This database currently holds 59 events including one meteorite, seven explosions, and 12 rocket launches. For each event, metadata, infrasound and seismic record sections, ...
The cochlear stria vascularis produces the positive endocochlear potential (EP) and the endolymph. Both the EP and the endolymph are essential for the physiological function of hair cells. The interme
Peripheral neural responses to cochlear stimulation via electrically evoked compound action potentials (ECAPs) of differing pulse distance and interphase gap
Fish possess two separate systems for detection of low-level sound and water motions in the low-frequency range: the inner ear and the lateral line. The relative roles of these systems in normal fish behaviour is still not clear. There is, for instance, a lack of experimental evidence showing the involvement of the lateral line and the inner ear in detection of infrasound, in directional hearing in the near field, and in detection and attack of swimming prey below the surface. To provide a useful tool for such studies, we have developed a pharmacological method for selective and reversible blocking of the lateral line in the roach (Rutilus rutilus). By recording multi-unit activity from the lateral line nerve and microphonic potentials from the inner ear, we have shown that cobalt ions in the external water may completely block the mechanosensitivity of the lateral line without affecting the utricular microphonic activity. This inhibiting effect of Co2+ is antagonized by Ca2+, making the ratio ...
Synonyms for Acoustic reflex in Free Thesaurus. Antonyms for Acoustic reflex. 26 synonyms for reflex: automatic, spontaneous, instinctive, involuntary, impulsive, knee-jerk, unthinking, automatic, impulsive, instinctive, involuntary.... What are synonyms for Acoustic reflex?
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Select-A-Strike clappers are adjustable by rotating the clapper screw slightly counter-clockwise until the clapper is free to rotate. Rotate the clapper to the desired position and retighten the screw.. Quick-Adjust clappers (See Fig. 3) are adjustable without loosening the clapper screw. In fact, the clapper screw should never be turned. This screw is locked to the clapper shaft by a special chemical bond between the screw and shaft. To adjust, rotate clapper until it clicks into the desired position. NOTE: DO NOT TAKE YOUR QUICK-ADJUST CLAPPER APART. THEY MUST BE RETURNED TO THE FACTORY FOR ANY REPAIRS NEEDED.. Try it! On all bells C8 and below in pitch, three decidedly different impact tones can be achieved. This permits a selection of mellow or more brilliant tones to be generated in your bells, according to your tonal preference. These options provide a soft mellow strike tone designated by the letter S imprinted on the clapper insert, a medium tone designated by M on the insert, and ...
Below about 50 kHz the level of ambient noise in the sea increases continuously towards lower frequencies. In the infrasound range the spectral slope is particularly steep. This low-frequency noise may propagate long distances with little attenuation, causing a directional pattern of infrasound in the sea. Using a standing-wave acoustic tube, we have studied the sensitivity of cod to infrasound down to 0.1 Hz by means of the cardiac conditioning technique. The threshold values, measured as particle acceleration, showed a steady decline towards lower frequencies below 10 Hz, reaching a value close to 10(−5)ms-2 at 0.1 Hz. The spectrum level at 0.1 Hz in the sea ranges between 120 and 180 dB (re 1 microPa), with corresponding particle accelerations from less than 10(−6) to more than 10(−4)ms-2. The sensitivity of cod is thus sufficient to detect the highest levels of ambient infrasound, and we put forward the hypothesis that fish may utilize information about the infrasound pattern in the ...
Definition of acoustic reflex threshold in the Financial Dictionary - by Free online English dictionary and encyclopedia. What is acoustic reflex threshold? Meaning of acoustic reflex threshold as a finance term. What does acoustic reflex threshold mean in finance?
TY - JOUR. T1 - Intracellular Potential Changes of Cortis Organ With Anoxia. AU - Nuttall, Alfred L.. AU - Lawrence, Merle. PY - 1979/10. Y1 - 1979/10. N2 - Intracellular measurements of the resting cell membrane potentials of guinea pig Cortis organ were made in order to determine the sensitivity of this cell potential to anoxic hypoxia (a lowered oxygen state due to lack of respiratory oxygen) and to establish differences according to cell types or morphologic regions of the sensory epithelium. The negative cell potentials measured from successful electrode penetrations were found to be relatively more stable and resistant to change during a 120-s period of anoxia than was the positive endocochlear potential. The intracellular resting potentials were also much slower to recover after resumption of respiration. Data obtained from various cells in two different regions of Cortis organ indicate that Cortis organ is receiving oxygen from both the perilymph and the endolymph. An iontophoretic ...
Auditory evoked potentials (AEP) are highly demanded during the whole process of equipping patients with cochlear implants (CI). They play an essential role in preoperative diagnostics, intraoperative testing, and postoperative monitoring of auditory performance and success. The versatility of AEPs is essentially enhanced by their property to be evokable by acoustic as well as electric stimuli. Thus, the electric responses of the auditory system following acoustic stimulation and recorded by the conventional surface technique as well as by transtympanic derivation from the promontory (Electrocochleography [ECochG]) are used for the quantitative determination of hearing loss and, additionally, electrically evoked compound actions potentials (ECAP) can be recorded with the intracochlear electrodes of the implant just adjacent to the stimulation electrode to check the functional integrity of the device and its coupling to the auditory system ...
The MS4630B is suitable for electronics production lines demanding fast and accurate device measurements. It is particularly well suited to accurate, high-speed evaluation of IF filter resonance and group delay characteristics, among others.
A feverish quest exists to uncover the events that lead to cochlear amplification in mammals. The role of the OHC is certainly paramount, and we now have identified many componentsthat form the basis of the cells unique contribution. In my mind, a few observations leadthe story on this hot topic, including the molecular identification of the OHC motor, its modulation by anions and the demonstration of the motors anion transport capabilities. Here I review some of this recent work.. ...
Offered inÂ- 10-67 GHz models, R&S ZVAX-TRM conditions signals from R&S ZVA network analyzers and returns them to analyzer or outputs them via integrated test ports. Users can measure parameters such as compression, noise figure, and group delay, even on 3-port T/R modules, with DUT having to be connected only once. When combined with 4-port analyzer with 4 internal sources,... Read More » ...
Hand Tools, including DEWALT - 23-Piece 1/2 Drive Combination Socket Set DWMT73813, Wilton - 746 Mechanics Vice, DEWALT - Compound Action..
Plants to 1.5 cm high, in hoary green to gray-green cushions, opaque-green to nearly black below. Leaves loosely imbricate when dry, loosely erect-spreading when moist, somewhat concave but not at all keeled, to 3 mm long with the awn constituting nearly 1/2 of that length, ovate-lanceolate from a loosely sheathing somewhat expanded base, 2.5-3.5: 1. Median leaf cells in regular longitudinal rows, unistratose in the expanded base but uniformly bistratose in the limb, smooth, to 7 µm wide, isodiametric with lumens irregular but without corner thickenings. Marginal cells not differentiated. Basal juxtacostal cells elliptical, to 3: 1, to 15 µm wide, with irregularly thickened lateral walls. Basal marginal cells transversely elongate, 0.5-0.7: 1, to 15 µm wide. Costa flared at the base and filling 1/3-1/4 of immediate leaf base, narrowed and obscure above, percurrent in the somewhat acuminate awn. Costa cross-section at leaf middle broad and flattened, less than 1.5 times as thick as the ...
Although outer hair cells (OHCs) play a key role in cochlear amplification, it is not fully understood how they amplify sound signals by more than 100 fold. Two competing or possibly complementary mechanisms, stereocilia-based and somatic electromotility-based amplification, have been considered. Lacking knowledge about the exceptionally rich protein networks in the OHC plasma membrane, as well as related protein-protein interactions, limits our understanding of cochlear function. Therefore, we focused on finding protein partners for two important membrane proteins: Cadherin 23 (cdh23) and prestin. Cdh23 is one of the tip-link proteins involved in transducer function, a key component of mechanoelectrical transduction and stereocilia-based amplification. Prestin is a basolateral membrane protein responsible for OHC somatic electromotility. Using the membrane-based yeast two-hybrid system to screen a newly built cDNA library made predominantly from OHCs, we identified two completely different groups of
18 yrs old Female asked about Auditory neuropathy, 1 doctor answered this and 67 people found it useful. Get your query answered 24*7 only on | Practo Consult
Impaired stria vascularis integrity upon loss of E cadherin in basal cells is an eagle-i resource of type Journal article at eagle-i Network Shared Resource Repository.
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Grant finansowany przez: The J. William Fulbright Foreign Scholarship Board & The U.S. Department of State Nr P008/00 (2000-2001) - Kierownik Projektu i Główny Wykonawca "Identifying in an Animal Model Criteria for the Intraoperative Monitoring of Cochlear Function During Neuro-Otologic Surgery in Patients with Cerebello-Pontine Angle Tumors Using Otoacoustic Emissions ...
The key to keeping your chinchilla healthy is to give it a balanced diet. And hay is one of the most ideal foods for chinchilla, which contributes a lot of
differences in human TM waves relative to those of other mammals.. TM wave properties were measured in samples taken from human cadavers ...
Can. J. Bot. 44: 609. 1966. -- Merceya latifoia Kindb. in Mac., Bull. Torr. Bot. Club 16: 94. 1889. -- Scopelophila latifolia (Kindb.) Ren. & Card., Rev. Bryol. 19: 92. 1892. Plants in thick turfs or as scattered tufts to 2.5 cm high, dark-green mostly with a reddish-brown cast. Leaves in a comose apical cluster, spreading when moist but keeled along costa and loosely reflexed near margins when dry, obovate to spatulate, 3.5-4.5 mm long, about 2.5: 1. Median laminal cells pluripapillose with low and inconspicuous punctiform papillae, to 16 µm broad, in straight rows radiating from costa to leaf margin, with lumen/wall ratio 4-8: 1, quadrate to hexagonal with angular lumens and without corner thickenings. Basal juxtacostal cells rectangular with straight and thin lateral walls, to 30 µm broad, 2-5: 1, smooth. Marginal cells abruptly larger than median cells, about twice as deep as wide, mostly reddish pigmented, less papillose and thicker-walled than adjacent laminal cells. Basal marginal cells ...
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Looking for online definition of Auditory Neuropathy, Autosomal Dominant 1 in the Medical Dictionary? Auditory Neuropathy, Autosomal Dominant 1 explanation free. What is Auditory Neuropathy, Autosomal Dominant 1? Meaning of Auditory Neuropathy, Autosomal Dominant 1 medical term. What does Auditory Neuropathy, Autosomal Dominant 1 mean?
Auditory neuropathy is diagnosed when person has normal OAE reading but absent or abnormal Auditory Br ainstem Response. Therefore from OAE and ABR results indicated that hair cell of cochlear is intact but the transmission of auditory nerve to brain is impaired.. Treatment and intervention for auditory neuropathy. There are a few treatment and intervention options for Auditory Neuropathy. However the potential benefit of treatment and intervention are vary to individual.. Frequency modulation (FM) systems. Some professionals reported frequency modulation (FM) systems are helpful for auditory neuropathy with normal hearing. Frequency modulation (FM) system is a device that can transmit sound directly to the listener by sound wave. By using FM system, the listener could concentrate to the speech better and would be useful especially in noisy environment.. ...
INTRODUCTION: the aim of this study was to investigate cochlear functions in patients with hyperemesis gravidarum (HG). METHODES: twenty-nine HG patients (58 ears) and 31 healthy control subjects (62 ears) were included. Audiometry testings at 250 and 500 Hz and 1, 2, 4, 8, 10, 12, 14, 16 kHz were performed to the patients and controls. RESULTS: mean age of patients with HG was 26,5 4,4 years and the mean age of control group was 28,0 4,2 years. At the time of the tests mean gestational age of the HG group and controls were 9 and 11 weeks respectively. No differences were observed between the groups in tympanic membrane status, orother otolaringological evaluations. No significant differences were observed in audiometric tests at any frequencies between the groups (p values for all>0.05). CONCLUSION: there was not a difference between pregnant cases with HG and cases with normal pregnancy in terms of audimetric tests. Cochlear functions are not affectedremarkably in women with HG.
Randomized, double-blind, placebo-controlled safety, pharmacokinetic, pharmacodynamic study of oral SPI-1005 in adults with Menieres disease. All subjects will undergo baseline audiometric testing and have their severity of sensorineural hearing loss, tinnitus and vertigo determined before the start of a 21-day course of treatment with SPI-1005 or placebo. During treatment with SPI-1005, and 7 days and 28 days following the cessation of SPI-1005, subjects will have their hearing loss, tinnitus and vertigo assessed. Additional testing including electrocochleography will be performed at baseline, at the end of SPI-1005 treatment, and 28 days after the SPI-1005 treatment has stopped. Six outpatient visits will be performed over a 7-week period ...
Learn more about Auditory Neuropathy at TriStar Southern Hills DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Learn more about Auditory Neuropathy at Doctors Hospital of Augusta DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Mechanical responses in the basal turn of the guinea-pig cochlea are measured with low-level broad-band noise as the acoustical stimulus [for details see de Boer and Nuttall, J. Acoust. Soc. Am. 101, 3583-3592 (1997)]. Results are interpreted within the framework of a classical three-dimensional model of the cochlea that belongs to a very wide class of nonlinear models. The use of linear-systems analysis for this class of nonlinear models has been justified earlier [de Boer, Audit. Neurosci. 3, 377-388 (1997)]. The data are subjected to inverse analysis with the aim to recover the effective basilar-membrane impedance. This is a parameter function that, when inserted into the model, produces a model response, the resynthesized response, that is similar to the measured response. With present-day solution methods, resynthesis leads back to an almost perfect replica of the original response in the spatial domain. It is demonstrated in this paper that this also applies to the response in the frequency
(article taken from empresschinchilla.com) Chinchilla, A Cellulose-Splitter Rodent Wendell Bird In the chinchillas native habitat, in which it has lived for many thousands of years, this animal has existed with a minimum of rainfall and other sources of water and has been able to thrive on relatively low protein fibers, dried grasses in a realtively…