The human body is surrounded by a micro‐climate which results from its convective release of heat. In this study, the air temperature and flow velocity of this micro‐climate were measured in a climate chamber at various room temperatures, using a thermal manikin simulating the heat release of the human being. Different techniques (Particle Streak Tracking, thermography, anemometry, and thermistors) were used for measurement and visualization. The manikin surface temperature was adjusted to the particular indoor climate based on simulations with a thermoregulation model (UCBerkeley Thermal Comfort Model). We found that generally, the micro‐climate is thinner at the lower part of the torso, but expands going up. At the head, there is a relatively thick thermal layer, which results in an ascending plume above the head. However, the micro‐climate shape strongly depends not only on the body segment, but also on boundary conditions: the higher the temperature difference between the surface ...
Except as otherwise noted, the content of this page is licensed under the Creative Commons Attribution 4.0 License, and code samples are licensed under the Apache 2.0 License. For details, see the Google Developers Site Policies. Java is a registered trademark of Oracle and/or its affiliates.. Last updated 2021-04-22 UTC.. ...
TY - JOUR. T1 - Deletions and epimutations affecting the human 14q32.2 imprinted region in individuals with paternal and maternal upd(14)-like phenotypes. AU - Kagami, Masayo. AU - Sekita, Yoichi. AU - Nishimura, Gen. AU - Irie, Masahito. AU - Kato, Fumiko. AU - Okada, Michiyo. AU - Yamamori, Shunji. AU - Kishimoto, Hiroshi. AU - Nakayama, Masahiro. AU - Tanaka, Yukichi. AU - Matsuoka, Kentarou. AU - Takahashi, Tsutomu. AU - Noguchi, Mika. AU - Tanaka, Yoko. AU - Masumoto, Kouji. AU - Utsunomiya, Takeshi. AU - Kouzan, Hiroko. AU - Komatsu, Yumiko. AU - Ohashi, Hirofumi. AU - Kurosawa, Kenji. AU - Kosaki, Kenjiro. AU - Ferguson-Smith, Anne C.. AU - Ishino, Fumitoshi. AU - Ogata, Tsutomu. PY - 2008/2. Y1 - 2008/2. N2 - Human chromosome 14q32.2 carries a cluster of imprinted genes including paternally expressed genes (PEGs) such as DLK1 and RTL1 and maternally expressed genes (MEGs) such as MEG3 (also known as GTL2), RTL1as (RTL1 antisense) and MEG8 (refs. 1,2), together with the intergenic ...
浜松市城西浄化センターにおけるMBRの初期運転について (第46回下水道研究発表会講演集) (2009 ...
Definition of robertsonian translocation in the Legal Dictionary - by Free online English dictionary and encyclopedia. What is robertsonian translocation? Meaning of robertsonian translocation as a legal term. What does robertsonian translocation mean in law?
Robertsonian translocations (RBT) are associated with an increased risk of aneuploidy. Single RBT carriers are the most common balanced rearrangement among the carrier couples with the history of spontaneous abortion. However, double Robertsonian translocations (DRBT), in which two balanced RBT occur simultaneously, are an extremely rare condition. A 9-year-old mentally normal ...
A Robertsonian translocation is a chromosomal abnormality that generally doesnt cause health problems. However, it can affect pregnancy, especially when it results in a fetus with a genetic condition that is incompatible with life. Well tell you what you can do if you have or suspect you have this translocation.
It is clear that, although we have learned much about the biology of MM, many questions remain. All of the available data suggest that IgH translocations are present in a majority (∼50-60%) of tumors, yet are not sufficient to exert the full malignant potential of the clone. Although early dysregulation of cyclin D1, D2, or D3 may represent a unifying event, it seems likely that two distinct pathways exist in the pathogenesis of MM. One pathway appears to involve an early IgH translocation that usually includes one of the four recurrent partners (11q13, 4p16, 16q23, 6p21), and mostly is associated with a nonhyperdiploid chromosome content. The second pathway infrequently, if ever, involves an early IgH translocation but mostly is associated with a hyperdiploid chromosome content, perhaps a reflection of intrinsic genetic instability, although we have virtually no understanding of this pathway. The timing and nature of additional genetic events that are involved in early pathogenesis is ...
It is clear that, although we have learned much about the biology of MM, many questions remain. All of the available data suggest that IgH translocations are present in a majority (∼50-60%) of tumors, yet are not sufficient to exert the full malignant potential of the clone. Although early dysregulation of cyclin D1, D2, or D3 may represent a unifying event, it seems likely that two distinct pathways exist in the pathogenesis of MM. One pathway appears to involve an early IgH translocation that usually includes one of the four recurrent partners (11q13, 4p16, 16q23, 6p21), and mostly is associated with a nonhyperdiploid chromosome content. The second pathway infrequently, if ever, involves an early IgH translocation but mostly is associated with a hyperdiploid chromosome content, perhaps a reflection of intrinsic genetic instability, although we have virtually no understanding of this pathway. The timing and nature of additional genetic events that are involved in early pathogenesis is ...
I am a 42-year-old woman struggling with infertility from a Robertsonian Translocation. My husband is 36 and we have been trying to get pregnant for two years
I am a 42-year-old woman struggling with infertility from a Robertsonian Translocation. My husband is 36 and we have been trying to get pregnant for two years
فناوری بیوراکتور غشایی (MBR) می‌تواند به عنوان فرآیندی یک مرحله‌ای برای تصفیه انواع فاضلابها به کار گرفته شود و پسابی با کیفیت نسبتاً خوب و مناسب، برای استفاده مجدد تولید نماید. در این تحقیق قابلیت کاربرد فرآیند MBR در فاضلابهای نفتی مورد بررسی قرار گرفته است. غشای مورد استفاده یک غشای میکروفیلتراسیون لوله‌ای بود که برای جداسازی و برگشت دادن بیوماس، مواد جامد سوسپانسه و مولکول‌های سنگین خروجی از بیوراکتور به کار رفت. دمای راکتور در محدوده 36-34 درجه سانتی‌گراد حفظ شد. در محدوده غلظت COD 500-2000 میلی گرم بر لیتر، راندمان حذف بین 93تا 97 درصد حاصل گردید و غلظت MLSS نیز
Enables deprecated DOS compatible mode, in this mode library checks for cylinders boundary, cases about CHS addressing and another obscure things.. ...
Hi there, I am researching chromosome 2 fusion theory. The theory that chromosome 2 and 3 was fused by a Robertsonian Translocation in two human-chimp common ancestors which mated giving us our chromosome 2 and 46 chromosomes instead of the other higher primates 48.. I was attempting to understand what the odds of this occurring were, to which end I want to know the odds that a chimp baby will be born with this mutation. I understand that 1 in 1000 human babies are born with a Robertsonian Translocation, is it the same for chimps?. ...
TY - JOUR. T1 - Evidence for involvement of a Robertsonian translocation 13 chromosome in formation of a ring chromosome 13. AU - Stetten, G.. AU - Tuck-Muller, C. M.. AU - Blakemore, Karin. AU - Wong, C.. AU - Kazazian, Haig. AU - Antonarakis, S. E.. PY - 1990. Y1 - 1990. UR - http://www.scopus.com/inward/record.url?scp=0025670533&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0025670533&partnerID=8YFLogxK. M3 - Article. C2 - 2077349. AN - SCOPUS:0025670533. VL - 7. SP - 479. EP - 484. JO - Molecular Biology and Medicine. JF - Molecular Biology and Medicine. SN - 0735-1313. IS - 6. ER - ...
Background: Robertsonian translocations are structural chromosomal abnormalities caused by fusion of two acrocentric chromosomes. In carriers of such translocatio...
Chromosome translocations in peripheral blood lymphocytes of normal, healthy humans increase with age, but the effects of gender, race, and cigarette smoking on background translocation yields have not been examined systematically. Further, the shape of the relationship between age and translocation frequency (TF) has not been definitively determined. We collected existing data from 16 laboratorie
This Blanchland route here is a mecca for soulful, moortop, mud-in-your-eye mountain biking thats as good as anywhere in the world.
Tcl1兔多克隆抗体(ab32813)可与人样本反应并经WB实验严格验证,被1篇文献引用。中国75%以上现货,所有产品均提供质保服务,可通过电话、电邮或微信获得本地专属技术支持。
Q&A. Q:什麼是自體免疫檢查?. A:少數人的免疫系統會攻擊自己的胚胎,造成胚胎無法著床或反覆流產。. 用抽血檢查即可知道體內是否具有特殊抗體。. Q:我需要做自體免疫檢查嗎?. A:1.累計植入10顆外表漂亮之胚胎或5顆囊胚沒成. 2.不明原因不孕、高齡、卵巢早衰(老)、體質過敏者. 3.反覆流產或習慣性流產. 以上只要有任一項符合,建議您做自體免疫篩檢。. Q:什麼時候可以做檢查?. A:無月經週期限制,任何時間皆可。. 因某些自體免疫反應可能是於懷孕後才啟動,建議可於懷孕時或剛流產後檢驗. ...
हाल ही में, केंद्र सरकार ने केन्द्रीय अन्वेषण ब्यूरो (सीबीआई) निदेशक आलोक वर्मा की जगह जॉइंट डायरेक्टर एम नागेश्वर राव को अंतरिम निदेशक नियुक्त किया है। सरकार ने
崇越指出,受益於先進製程需求強勁,晶圓代工廠12吋廠產能第4季還是會持續滿載;不過關於40/65奈米等其他製程,晶圓代工廠第4季稼動率則將下修至7-8成,此部分需求將會下滑。而由於第1、第4季向來是崇越的傳統淡季,因此目前對第4季營運亦是保守看待。. 不過由於崇越1-8月累積營收已達93.78億元,未來單月營收僅要達到10億元的門檻,今年全年營收就可追平去年,因此法人也普遍看好,崇越今年營收至少可和去年持平。 惟在今年獲利表現方面,崇越則是看的較為保守,指出由於毛利率較優的石英,因晶圓廠製程進行調整,減少爐管的使用、增加自動化設備的比重,因此出貨有不小衰退。就以上半年石英的營收佔比而言,已從去年同期的1成滑落至5-6%左右,因此估計今年獲利恐會往下走。 ...
Looking for online definition of Robertsonian in the Medical Dictionary? Robertsonian explanation free. What is Robertsonian? Meaning of Robertsonian medical term. What does Robertsonian mean?
A familial lympho-epithelial thymoma with constitutional chromosomal translocation t (14;20) (q24;p13) is presented: the thymoma and its particular translocation are present in the mother and the two sons of her offspring. The small number of cases do not allow establishing any relation between thymoma and this particular translocation. Concerning genetic counseling, an annual thoracic radiography is necessary for all the other family members, carriers or not of the translocation.
IGH translocations induce up-regulation of different oncogenes order propecia 1 mg on line hair loss 6 months after giving birth, it is Learning Objectives possible that all IGH translocations involved in MM converge on a ● To understand that myeloma should no longer be considered common pathway that is essential in the pathogenesis of the disease as a single entity and cause the inhibition of differentiation and an increase in cell ● To understand that better tools for diagnosis and monitoring survival and proliferation order 5 mg propecia with visa hair loss in men quilters. Gene expression profiling (GEP) analysis treatment efficacy are being implemented has demonstrated that expression of the cyclin proteins (CCND1, ● To understand that the treatment goal is to find the best CCND2, and CCND3) is increased in almost all MM patients, possible balance among efficacy, toxicity, and cost supporting the hypothesis that there is a potential unifying event in its pathogenesis. The ...
Kagami M, Sekita Y, Nishimura G, Irie M, Kato F, Okada M, Yamamori S, Kishimoto H, Nakayama M, Tanaka Y, Matsuoka K, Takahashi T, Noguchi M, Tanaka Y, Masumoto K, Utsunomiya T, Kouzan H, Komatsu Y, Ohashi H, Kurosawa K, Kosaki K, Ferguson-Smith AC, Ishino F, Ogata T. Deletions imprinted region: implications for the development of paternal and maternal upd(14)-likeand epimutations affecting the human chromosome 14q32.2 phenotypes. Nat Genet 40: 237-242, ...
TY - JOUR. T1 - Impact of primary molecular cytogenetic abnormalities and risk of progression in smoldering multiple myeloma. AU - Rajkumar, S. V.. AU - Gupta, V.. AU - Fonseca, R.. AU - Dispenzieri, A.. AU - Gonsalves, W. I.. AU - Larson, D.. AU - Ketterling, R. P.. AU - Lust, J. A.. AU - Kyle, R. A.. AU - Kumar, S. K.. PY - 2013/8/1. Y1 - 2013/8/1. N2 - We studied 351 patients with smoldering multiple myeloma (SMM) in whom the underlying primary molecular cytogenetic subtype could be determined based on cytoplasmic immunoglobulin fluorescent in situ hybridization studies. Hundred and fifty-four patients (43.9%) had trisomies, 127 (36.2%) had immunoglobulin heavy chain (IgH) translocations, 14 (4%) both trisomies and IgH translocations, 53 (15.1%) no abnormalities detected and 3 (0.9%) had monosomy13/del(13q) in the absence of any other abnormality. Among 127 patients with IgH translocations, 57 were t(11;14), 36 t(4;14), 11 musculoaponeurotic fibrosarcoma (MAF) translocations, and 23 other or ...
Author Summary Each time a mammalian cell duplicates its genome in preparation for cell division it activates thousands of so called
Background:This study was conducted to analyze the frequency, expression patterns, and the impact of individual proteins BCL2, BCL6, and p53 on overall survival (OS) in adult, diffuse large B-cell lymphoma (DLBCL) Patients. BCL2 gene was further investigated for potential alterations at the DNA level and correlated with OS. Materials and Methods: A total of 117 adult well-characterized DLBCL cases were included. The panel of antibodies comprised CD45, CD20, CD79a, CD3, BCL2, BCL6, and p53. PCR was also employed to correlate the events at the DNA level in BCL2. Results: The mean and median ages were 47.74 and 49 with a M:F ratio of 2.07:1. The incidence of BCL2, BCL6, and p53 expression was observed in 64.10%, 37.60%, and 52.13% of cases, respectively. Amplifiable quality DNA was available from 90 cases. BCL2/IGH translocation was found in 35/90 Patients (38.88%) with 24 cases showing BCL2 (MBR)/IGH and 11 cases BCL2 (mcr)/IGH translocation. No association between BCL2 overexpression and BCL2 /IGH
The chromosomal translocation t(1;19)(q23;p13) and its variant form der(19)t(1;19) found in 3-5% of acute lymphoblastic leukemia (ALL) results in the expression of the E2A-PBX1 fusion transcript. Although strongly associated with a pre-B immunophenotype, we report the occurrence of t(1;19) in bone m …
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When a fusion sequence combines upper-case and lower-case nucleotides, this indicates the approximate location of the boundary between both partner genes ...
When a fusion sequence combines upper-case and lower-case nucleotides, this indicates the approximate location of the boundary between both partner genes ...
Bioingeniería Latinoamericana junto a R&D Equipment Company presentes en CAENA 2013. http://www.engormix.com/mailredirect/notif.asp?lnk_id=3227595&mbr_id=0
Maternal uniparental disomy (UPD) for chromosome 14 [upd(14)mat] may cause a characteristic phenotype with growth and developmental deficiency and precocious puberty. We report the case of a Japanese infant with an isochromosome 14 [i(14q)] and intrauterine growth retardation (IUGR). The infant is o …
Translocation is the exchange of chromosome segments, usually between nonhomologous chromosomes. There are two primary types of translocations: reciprocal translocations and Robertsonian translocations. A reciprocal translocation occurs when segments from nonhomologous chromosomes break off, with segment attaching to the other chromosome and vice-versa. A Robertsonian translocation occurs when two acrocentric chromosomes (chromosomes with tiny short arms, meaning the centromere is near one end) fuse at the centromere and lose their short arms.. Reciprocal translocations usually involve only two chromosomes, meaning the total chromosome number is unchanged. Reciprocal translocation are typically harmless, despite being more common in individuals so retarded that they require institutional care. There are three kinds of reciprocal translocation: alternate; adjacent-1; and adjacent-2.. Robertsonian translocations lead to a balanced karyotype with only 45 chromosomes. Because acrocentric short arms ...
A Robertsonian translocation 45,XY, t(13q; 14q) was detected in the leukocyte cultures of a phenotypically normal male. Silver staining technique for nucleolus organizer regions revealed that both acrocentrics involved in the translocation had lost their nucleolus organizers.
TY - JOUR. T1 - Mantle cell lymphoma with a novel t(11;12)(q13;p11.2). T2 - a proposed alternative mechanism of CCND1 up-regulation. AU - Menke, Joshua R.. AU - Vasmatzis, George. AU - Murphy, Stephen. AU - Yang, Lin. AU - Menke, David M.. AU - Tun, Han W. AU - King, Rebecca. AU - Smoley, Stephanie A.. AU - Ketterling, Rhett P.. AU - Sukov, William R.. PY - 2017/6/1. Y1 - 2017/6/1. N2 - Mantle cell lymphoma (MCL) is typically characterized by t(11;14), which places the IGH@ enhancer elements upstream of CCND1. This fusion results in up-regulation of CCND1 and consequently its protein product cyclin D1. Recent studies have shown that in MCL, mutations or translocations occurring within the 3′ untranslated region (UTR) of the CCND1 gene can result in a truncated mRNA transcript that is more stable and associated with more aggressive disease. We identified a case of MCL showing cyclin D1 overexpression by immunohistochemistry and a t(11;12)(q13;p11.2) by conventional cytogenetic studies. ...
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Syvanen M, Ducore J. Whole genome comparisons reveals a possible chimeric origin for a major metazoan assemblage. Journal of Biological Systems, (18) 261-75. 2010. Zunino SJ, Storms DH, Ducore JM. Novel in vivo model of inducible multi-drug resistance in acute lymphoblastic leukemia with chromosomal translocation t(4;11). Cancer Lett. 2010 Oct 1;296(1):49-54. Epub 2010 Apr 9.. Zunino SJ, Storms DH, Ducore JM. Parthenolide treatment activates stress signaling proteins in high-risk acute lymphoblastic leukemia cells with chromosomal translocation t(4;11). Int J Oncol. 2010 Nov;37(5):1307-13.. Gofman I, Ducore JM. Risk Factors for the Development of Obesity in Children Surviving ALL and NHL. Journal of Pediatric Hematologyl Oncology, 31(2): 101-107. 2008. Zunino SJ, Ducore JM, Storms DH. Parthenolide induces significant apoptosis and production of reactive oxygen species in high-risk pre-B leukemia cells. Cancer Letters, 254(1): 119-27. 2007. Winter S, Holdsworth MT, Devidas M, Raisch OW, ...
Do You Have Follicular Lymphoma? Join friendly people sharing true stories in the I Have Follicular Lymphoma group. Find forums, advice and chat with groups who share this life experience. A Follicular Lymphoma anonymous support group with informatio...
Robertsonian translocation: Two breaks occur in separate chromosomes, usually the 14th and 21st chromosomes. There is rearrangement of the genetic material so that some of the 14th chromosome is replaced by extra 21st chromosome. So while the number of chromosomes remain normal, there is a triplication of the 21st chromosome material ...
Liang X, Jones A, Giller RH, Swisshelm K, McGavran L, Meltesen L, Carstens B, McGranahan AN, Albano EA. Primary high-grade B-cell lymphoma of the breast with concurrent IGH-BCL2 and MYC-IGL translocations in an adolescent patient. Pediatr Dev Pathol. 2011 Sep-Oct; 14(5):402-6 ...
Changes in how follicular lymphoma is managed have led to substantial improvement in prognosis and over all survival for patients with the disease.
For patients with Relapsed/Refractory Follicular Lymphoma, second-line therapies are often successful in providing another remission.
New Insights into Transformed Follicular Lymphoma from the National LymphoCare Study - From the Blood Journals, News - ASH Clinical News
FDA granted approval to Bayer Healthcare Pharmaceuticals inhibitor Aliqopa (copanlisib) for the treatment of adults with relapsed follicular lymphoma.
A CASE OF TRISOMY OF THE SHORT ARMS OF CHROMOSOME NO 4 WITH TRANSLOCATION T (4 P 21 P; 4 Q 21 Q) IN THE MOTHER = UN CAS DE TRISOMIE DES BRAS COURTS DU CHROMOSOME NO 4 AVEC TRANSLOCATION T (4 P 21 P; 4 Q 21 Q) CHEZ LA MERE)FURBETTA M; ROSI G; COSSU P et al.1975; HUMANGENETIK; DTSCH.; DA. 1975; VOL. 26; NO 2; PP. 87-91; BIBL. 13 REF.Article ...
MBR merupakan salah satu teknologi baru untuk pengolahan air limbah dengan menggabungkan teknik pemisahan membran dengan metode lumpur aktif.. Ini dapat digunakan untuk limbah kota dan pengolahan air limbah industri dan menggantikan tangki sedimentasi sekunder dalam menghilangkan partikel tersuspensi. sehingga dapat meningkatkan laju penyisihan nitrogen dan laju degradasi organik.. Sebagai sistem pengolahan air limbah fitur operasi sederhana. otomatisasi tinggi dan desain modular. itu juga ada di bawah keuntungan:. -Hemat 50% area pendudukan dibandingkan dengan sistem tradisional ...
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After a fairly normal and easy labor and delivery, Cal made his debut! He wasnt breathing well on his own and needed respiratory support. Because we knew he might be born with some abnormalities, we had lots of doctors ready to care for him right when he was born. A heart echo was one of the things they did right away, and the results came back showing quite a few defects with his little heart. At that point it was pretty clear he had the unbalanced chromosome translocation, but the microarray test results confirming this would take over a week to get back ...
Forbidden now has a big gun but who needs the Forbidden Dreadnought XT when the Druid is already billed as capable? In short... everyone. Let me explain.
This section includes notable fireplace mantels crafted in richly textured wood. Our featured mantels are traditional in form, and designed to enrich your s