The aim of this study was to determine the relationship between a purported luteinizing hormone/chorionic gonadotropin (LHCGR) high function polymorphism (rs4539842/insLQ) and outcome to controlled ovarian hyperstimulation (COH). This was a prospective study of 172 patients undergoing COH at the Fertility and IVF Center at GWU. DNA was isolated from blood samples and a region encompassing the insLQ polymorphism was sequenced. We also investigated a polymorphism (rs4073366 G | C) that was 142 bp from insLQ. The association of the insLQ and rs4073366 alleles and outcome to COH (number of mature follicles, estradiol level on day of human chorionic gonadotropin (hCG) administration, the number of eggs retrieved and ovarian hyperstimulation syndrome (OHSS)) was determined. Increasing age and higher day 3 (basal) FSH levels were significantly associated with poorer response to COH. We found that both insLQ and rs4073366 were in linkage disequilibrium (LD) and no patients were homozygous for both recessive
Looking for online definition of chorionic gonadotropic hormone in the Medical Dictionary? chorionic gonadotropic hormone explanation free. What is chorionic gonadotropic hormone? Meaning of chorionic gonadotropic hormone medical term. What does chorionic gonadotropic hormone mean?
TY - JOUR. T1 - Regulation of steroidogenesis by p53 in macaque granulosa cells and H295R human adrenocortical cells. AU - Cherian-Shaw, Mary. AU - Das, Rituparna. AU - Vandevoort, Catherine A.. AU - Chaffin, Charles L.. PY - 2004/12. Y1 - 2004/12. N2 - Ovulation and formation of a functional corpus luteum in primates involve cascades of events, including increased progesterone synthesis and changes in granulosa cell proliferation. However, critical gaps remain in our understanding of how an ovulatory gonadotropin surge initiates these processes. To more fully elucidate changes in the cell cycle during luteal formation, the actions of the tumor suppressor p53 were examined. Rhesus macaque granulosa cells were isolated during controlled ovarian stimulation protocols before (nonluteinized) or after (luteinized) an ovulatory gonadotropin stimulus. Phosphorylated p53 protein was detected in the cytoplasm of granulosa cells before and after human chorionic gonadotropin (hCG) treatment, whereas ...
Looking for online definition of Chorionic gonadotropin, beta subunit, human in the Medical Dictionary? Chorionic gonadotropin, beta subunit, human explanation free. What is Chorionic gonadotropin, beta subunit, human? Meaning of Chorionic gonadotropin, beta subunit, human medical term. What does Chorionic gonadotropin, beta subunit, human mean?
TY - JOUR. T1 - Elevated titers of the beta subunit of human chorionic gonadotropin in oophorectomized women being treated for trophoblastic disease. AU - Hatch, Kenneth D.. AU - Shingleton, Hugh M.. AU - Younger, Benjamin. AU - Boots, Larry R.. PY - 1980/5/1. Y1 - 1980/5/1. N2 - Radioimmunoassay has shown a cross-reaction of the beta subunit of human chorionic gonadotropin (HCG) with high levels of luteinizing hormone (LH) in the serum of four women who underwent bilateral oophorectomy as part of their treatment for trophoblastic disease. Administration of oral contraceptives led to suppression of the LH and beta subunit HCG titers.. AB - Radioimmunoassay has shown a cross-reaction of the beta subunit of human chorionic gonadotropin (HCG) with high levels of luteinizing hormone (LH) in the serum of four women who underwent bilateral oophorectomy as part of their treatment for trophoblastic disease. Administration of oral contraceptives led to suppression of the LH and beta subunit HCG ...
TY - JOUR. T1 - Comparative study of the steroidogenic effects of human chorionic gonadotropin and thieno[2,3-d]pyrimidine-based allosteric agonist of luteinizing hormone receptor in young adult, aging and diabetic male rats. AU - Bakhtyukov, Andrey A.. AU - Derkach, Kira V.. AU - Gureev, Maxim A.. AU - Darin, Dmitry V.. AU - Sorokoumov, Viktor N.. AU - Romanova, Irina V.. AU - Morina, Irina Yu. AU - Stepochkina, Anna M.. AU - Shpakov, Alexander O.. N1 - Bakhtyukov, A.A.; Derkach, K.V.; Gureev, M.A.; Darin, D.V.; Sorokoumov, V.N.; Romanova, I.V.; Morina, I.Y.; Stepochkina, A.M.; Shpakov, A.O. Comparative Study of the Steroidogenic Effects of Human Chorionic Gonadotropin and Thieno[2,3-D]pyrimidine-Based Allosteric Agonist of Luteinizing Hormone Receptor in Young Adult, Aging and Diabetic Male Rats. Int. J. Mol. Sci. 2020, 21, 7493.. PY - 2020/10/2. Y1 - 2020/10/2. N2 - Low-molecular-weight agonists of luteinizing hormone (LH)/human chorionic gonadotropin (hCG) receptor (LHCGR), which interact ...
Author(s): Segal, Thalia R; Amini, Peyvand; Wang, Junye; Peters, Gregory; Skomorovska-Prokvolit, Yelenna; Mainigi, Monica A; Goldfarb, James M; Mesiano, Sam; Weinerman, Rachel | Abstract: Gonadotropin-releasing hormone agonists (GnRHa) are used as an alternative to human chorionic gonadotropin (hCG) to trigger ovulation and decrease the risk of ovarian hyperstimulation syndrome. GnRHa is less potent at inducing ovarian vascular endothelial growth factor (VEGF), but may also affect endometrial angiogenesis and early placental development. In this study, we explore the effect of superovulation on endometrial angiogenesis during critical periods of gestation in a mouse model. We assigned female mice to three groups: natural mating or mating following injection with equine chorionic gonadotropin and trigger with GnRHa or hCG trigger. Females were killed prior to implantation (E3.5), post-implantation (E7.5), and at midgestation (E10.5), and maternal serum, uterus, and ovaries were collected. During peri
TY - JOUR. T1 - Analytical versus clinical sensitivity and specificity in pregnancy testing. AU - Emancipator, Kenneth. AU - Cadoff, Evan M.. AU - Burke, M. Desmond. PY - 1988/3. Y1 - 1988/3. N2 - A typical urine pregnancy test with the enzyme-linked immunoassay for human chorionic gonadotropin (Tandem Icon human chorionic gonadotropin) was performed as was a qualitative serum radioimmunoassay for human chorionic gonadotropin when the positive cutoff for the latter was set at 30 IU/L. There was 99.5% concordance between the two methods when performed on 871 simultaneous urine and serum specimens. Although the serum radioimmunoassay can detect levels of human chorionic gonadotropin as low as 10 IU/L, in this study the majority of patients with serum levels between 10 and 30 IU/L were not pregnant on clinical follow-up. Of nine patients with adequate clinical follow-up, a negative urine pregnancy test result, and a serum human chorionic gonadotropin level between 10 and 30 IU/L, only one proved to ...
TY - JOUR. T1 - Luteal function following ovarian stimulation in rhesus monkeys for in vitro fertilization. T2 - Atypical response to human chorionic gonadotropin treatment simulating early pregnancy. AU - VandeVoort, C. A.. AU - Hess, D. L.. AU - Stouffer, R. L.. PY - 1988. Y1 - 1988. N2 - This study determined if corpora lutea of hyperstimulated cycles in rhesus monkeys could be rescued by the pregnancy signal, chorionic gonadotropin (CG), given at the typical time of implantation. At menses, female monkeys received human follicle-stimulating hormone (hFSH, 60 IU, days 1 to 6) followed by human menopausal gonadotropin (hMG, 60 IU hFSH/60 IU luteinizing hormone [hLH], days 7 to 9). On day 10, human chorionic gonadotropin (hCG) was given to mimic the LH surge. Nine days later, a regimen of daily increasing doses of hCG (15 to 360 IU twice a day) was initiated to simulate rescue of the corpus luteum in early pregnancy. Serum levels of progesterone (P) increased through day 5 of the luteal phase ...
Aatsinki JT, Pietila EM, Lakkakorpi JT and Rajaniemi HJ (1992). Expression of the LH/CG receptor gene in rat ovarian tissue is regulated by an extensive alternative splicing of the primary transcript. Mol. Cell Endocrinol. 84: 127-135. http://dx.doi.org/10.1016/0303-7207(92)90079-L Apaja PM, Tuusa JT, Pietila EM, Rajaniemi HJ, et al. (2006). Luteinizing hormone receptor ectodomain splice variant misroutes the full-length receptor into a subcompartment of the endoplasmic reticulum. Mol. Biol. Cell 17: 2243- 2255. http://dx.doi.org/10.1091/mbc.E05-09-0875 PMid:16495341 PMCid:1446094 Ascoli M, Fanelli F and Segaloff DL (2002). The lutropin/choriogonadotropin receptor, a 2002 perspective. Endocr. Rev. 23: 141-174. http://dx.doi.org/10.1210/er.23.2.141 PMid:11943741 Bacich DJ, Rohan RM, Norman RJ and Rodgers RJ (1994). Characterization and relative abundance of alternatively spliced luteinizing hormone receptor messenger ribonucleic acid in the ovine ovary. Endocrinology 135: 735-744. ...
Beta hCG Test Definition - A beta hCG test is a blood test that monitors levels of the hormone human chorionic gonadotropin (hCG) present in the body....
ABOUT 1000 of testicular germ-cell tumours occur in men treated for maldescended testes (Whitaker, 1970). The risk of testicular tumour in men with maldescended testes has been estimated at 35 times that of normal men (Whitaker, 1970). Recently 2 case-control studies confirmed the increased risk of testicular tumour in maldescended testes (Morrison, 1976; Henderson et al., 1979). Testicular germ-cell (TGC) tumours may be preceded by carcinoma in situ in a biopsy several years before (Skakkebaek, 1972, 1978). Raised concentrations of serum o-foetoprotein (AFP) and serum human chorionic gonadotropin : subunit (hCG) often preceded other signs of relapse in nonseminomatous TGC tumours (Waldmann & McIntire, 1974). Serum AFP and serum hCG were measured as a screen for TGC tumours in men with maldescended testes, in addition to physical examination and testicular biopsy. The histological findings of the first 50 men biopsied have recently been reported elsewhere (Krabbe et al., 1979). In this paper we report
The placenta secretes chorionic gonadotropin beginning just after implantation. This glycoprotein consists of two chains. The α-chain is identical to the α-chains of three pituitary hormones - luteinizing hormone (LH), follicle stimulating hormone (FSH) and thyroid stimulating hormone (TSH). The β-chain is unique to gonadotropin. Signaling through its receptor, human chorionic gonadotropin (HCG) maintains the corpus luteum and causes it to secrete progesterone. Because HCG is usually secreted within seven days after conception, and because serum levels double every 2-3 days for the first two months of pregnancy, its presence in urine is the basis of home pregnancy tests. It is also used in fertility treatments. The β-chain is secreted by some tumors and its presence in urine can indicate testicular cancer. Most of our HCG products are purified from pregnancy urine, and are available in several formulations, including convenient vials of sterile filtered lyophilized powder standardized by HCG units.
Human chorionic gonadotropin (hCG) is a glycoprotein hormone (molecular weight: MW approximately 36,000 Dalton: Da) consisting of 2 noncovalently bound subunits. The alpha subunit (92-amino acids; naked protein MW 10,205 Da) is essentially identical to that of luteinizing hormone (LH), follicle-stimulating hormone, and thyroid-stimulating hormone (TSH). The alpha subunit is essential for receptor transactivation. The different beta subunits of the above hormones are transcribed from separate genes, show less homology, and convey the receptor-specificity of the dimeric hormones. The chorionic gonadotropin, beta gene (coding for a 145-amino acid, naked protein MW 15,531 Da, glycosylated subunit MW approximately 22,500 Da) is highly homologous to the beta subunit of LH and acts through the same receptor. However, while LH is a classical tropic pituitary hormone, hCG does not usually circulate in significant concentrations. In pregnant primates (including humans) it is synthesized in the ...
To the Editor:. Previously, we reported false-negative results generated by the OSOM human chorionic gonadotropin (hCG)1 Combo test (Genzyme Diagnostics) (1) and certain lots of the hCG Cardinal Health Combo SP brand rapid test device (SP hCG rapid test; Cardinal Health) (2) owing to increased concentrations of hCG β core fragment (hCGβcf). We refer to this phenomenon as the variant hook effect. In a hospital setting, these false negatives pose a substantial risk of adverse outcomes if pregnant patients are given treatments that can affect the fetus. This observation was reported to the US Food and Drug Administration, but to our knowledge no action has been taken to change these devices. These false negatives also pose considerable risk to women at home, because a negative pregnancy test result may cause delays in prenatal care and continued engagement in behavior that can endanger the fetus. In view of the variable sensitivity of point-of-care (POC) and over-the-counter (OTC) devices to ...
Detects the presence of human chorionic gonadotropin (HCG), which appears in urine very early in pregnancy. Regardless of the technical language, this test works just like most other pregnancy tests out there. It measures the levels of the pregnancy hormone human chorionic gonadotropin (HCG) in your urine. This hormone is produced by the cells of the embryo that will later form the placenta. The level of HCG starts to increase from its basal level of less than 5 mIU/mL directly after implantation, and doubles about each 48 hours during the first weeks of pregnancy ...
Intervention: Each subject in the PCOS group will receive dexamethasone 1 mg orally in the evening and return the next morning for an injection of 25ug of IV recombinant human chorionic gonadotropin. Subjects will the have blood drawn at -0.5, 0, 0.5, and 24 hours after hCG injection for steroid hormone measurements.. Dexamethasone: Each subject in each group will receive 1 mg of oral dexamethasone in the evening and return in the morning for an injection of 25ug of IV recombinant human chorionic gonadotropin. Subjects will also have blood drawn at times -0.5, 0, 0.5, and 24 hours after the injection of r-hCG for measurement of steroid hormones.. recombinant human chorionic gonadotropin (r-hCG): Each subject in each group will receive 1 mg of oral dexamethasone in the evening and return in the morning for an injection of 25ug of IV recombinant human chorionic gonadotropin (r-hCG). Subjects will also have blood drawn at times -0.5, 0, 0.5, and 24 hours after the injection. ...
The case of adenocarcinoma with human chorionic gonadtropin (HCG), primary in the male gallbladder, is extremely rare. A Medline search has shown only a few similar cases reported. We herein describe a case of primary gallbladder adenocarcinoma associated by ectopic HCG positive tumor cells in a 79-year-old male. Pathological examination showed a mixture of moderately and poorly differentiated adenocarcinoma with ectopic HCG and placental alkaline phosphatase (PlAP) in tumor cells, though the increase of serum or urinary HCG secretion was not confirmed. The literatures were also reviewed. A case of gallbladder cancer with ectopic HCG production is quite rare in the literature, though many similar cases in other site, especially in GI tract, are reported. Embryological consideration suggests the increased frequency of similar cases more than being thought now.
Human chorionic gonadotropin (hCG) has been regarded as a biomarker for the diagnosis of pregnancy and some cancers. Because the currently used methods (e.g., disposable Point of Care Testing (POCT) device) for hCG detection require the use of many less stable antibodies, simple and cost-effective methods for the sensitive and selective detection of hCG have always been desired. In this work, we have developed a graphene oxide (GO)-based fluorescent platform for the detection of hCG using a fluorescein isothiocyanate (FITC)-labeled hCG-specific binding peptide aptamer (denoted as FITC-PPLRINRHILTR) as the probe, which can be manufactured cheaply and consistently. Specifically, FITC-PPLRINRHILTR adsorbed onto the surface of GO via electrostatic interaction showed a poor fluorescence signal. The specific binding of hCG to FITC-PPLRINRHILTR resulted in the release of the peptide from the GO surface. As a result, an enhanced fluorescence signal was observed. The fluorescence intensity was directly
Beta-hCG ELISA kit is a reliable quantitative procedure for measuring beta human chorionic gonadotropin (beta-hCG) in serum samples. • Reactivity: Human
Xiaoyu Yang, H Ochin, Li Shu, Jinyong Liu, Jiandong Shen, Jiayin Liu, Changsong Lin, Yugui Cui Homozygous nonsense mutation Trp28X in the LHB gene causes male hypogonadism. J. Assist. Reprod. Genet.: 2018; PubMed 29476300 Yuxin Yang, Yonghong Shi, Yanjuan Hou, Ying Lu, Jinliang Yang CGB5 expression is independently associated with poor overall survival and recurrence-free survival in patients with advanced gastric cancer. Cancer Med: 2018; PubMed 29473345 Brett C Neill, Nathan C Bahr, Zachary Bryan, Daniel J Aires Cutaneous infection with Mycobacterium fortuitum after subcutaneous injection of human chorionic gonadotropin. Dermatol. Online J.: 2017, 23(8); PubMed 29469752 Ai Ling Liu, Hong Qing Liao, Jing Zhou, Yu Lin Nie, Cui Lan Zhou, Zhi Liang Li, Zi Fen Guo, Dong Xiu He, Yun Hua Zhu, Cui Ying Peng The role of FTO variants in the susceptibility of polycystic ovary syndrome and in vitro fertilization outcomes in Chinese women. Gynecol. Endocrinol.: 2018;1-5 PubMed 29463151 Saihua Ma, Ruihong ...
Nonomura, A., Mizukami, Y., Matsubara, F., Izumi, R., Nakanuma, Y., Hayashi, M., Watanabe, K. and Takayanagi, N. (1989), Human chorionic gonadotropin and alpha-fetoprotein in cholangiocarcinoma in relation to the expression of ras p21: an immunohistochemical study. Liver, 9: 205-215. doi: 10.1111/j.1600-0676.1989.tb00401.x ...
TY - JOUR. T1 - Persistent low concentration of human chorionic gonadotropin in a nonpregnant woman. AU - McCudden, Christopher R.. AU - Willis, Monte S.. AU - Grenache, David G.. PY - 2008/1/1. Y1 - 2008/1/1. UR - http://www.scopus.com/inward/record.url?scp=38749100191&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=38749100191&partnerID=8YFLogxK. U2 - 10.1373/clinchem.2007.092411. DO - 10.1373/clinchem.2007.092411. M3 - Article. C2 - 18024529. AN - SCOPUS:38749100191. VL - 54. SP - 209. EP - 213. JO - Clinical Chemistry. JF - Clinical Chemistry. SN - 0009-9147. IS - 1. ER - ...
Regulation of 3β‐Hydroxysteroid Dehydrogenase Activity by Human Chorionic Gonadotropin, Androgens, and Antiandrogens in Cultured Testicular ...
TY - JOUR. T1 - Influence of obesity on first trimester screening markers in singleton pregnant women enrolled at tertiary care hospital. AU - Varashree, B. S.. AU - Belle, Vijetha Shenoy. AU - Krishnananda Prabhu, R. V.. AU - Rao, Pragna. PY - 2019/1/1. Y1 - 2019/1/1. N2 - Pregnancy is diagnosed by the detection of beta human Chorionic Gonadotropin (beta hCG) in maternal serum or urine after implantation of the embryo. Primary function of hCG is to maintain the corpus luteum in early weeks of gestation. Pregnancy associated plasma protein A is a glycoprotein exhibits insulin like growth factor binding protein 4 protease activity, which regulates bioavailability of Insulin like Growth Factor-II. Maternal obesity increases the likelihood of serious pregnancy complications both for mother and infant. The altered maternal environment in women with a raised BMI could have adverse consequences for placental development and function thus we hypothesized if maternal body mass index is associated with ...
Equine chorionic gonadotropin (eCG) and lutropin (eLH) are heterodimeric glycoprotein hormones which are synthesized in the placenta and pituitary, respectively. The beta subunits of eCG and eLH, like their alpha subunits, arise from a single gene and have identical amino acid sequences. In contrast, the beta subunits of CG and LH in primates arise from different genes and differ in sequence. We have examined the structures of the Asn-linked oligosaccharides on eCG and eLH. eCG bears di- and tri-branched Asn-linked oligosaccharides terminating with Sia alpha 2,3 or 6Gal beta 1,4GlcNAc. In contrast, , 72% of the Asn-linked oligosaccharides on eLH have 1 or 2 branches terminating with the sequence SO4-4-GalNAc beta 1,4GlcNAc. The nonsulfated oligosaccharides on eLH are neutral (6% of the total) or have branches terminating with sialic acid-Gal (22% of the total). Since the alpha and beta subunits of eCG and eLH both contain the tripeptide motif, Pro-Xaa-Arg/Lys, recognized by the glycoprotein ...
ACCESS INFORMATION PRIOR TO THIS POST ON BETA β-hCG (human chorionic gonadotropin) is a glycoprotein that is initially secreted by trophoblast cells in
Admin , Articles , October 25, 2013. The HCG (human chorionic gonadotropin) examination is done to assess the quantity of the hormone HCG in blood or urine in order to check whether a female is pregnant. HCG is formed by the placenta in pregnancy.. HCG may also be produced unusually by certain tumors, particularly those that originate from an egg or sperm cell (germ cell tumors). Normally, HCG levels are tested in a woman who may have irregular tissue developing in her uterus, a molar pregnancy, or a cancer in the uterus rather than a normal pregnancy. Various HCG examinations may be made after a spontaneous abortion to be sure a molar pregnancy is not present. In a man, HCG levels may be valuated to help observe whether he has cancer of the testes.. Once the fertilized egg embeds, the growing placenta starts discharging HCG into blood. Some HCG also gets into the urine. HCG can be detected in the blood before the first missed menstrual period, as early as six days after implantation.. HCG helps ...
Gonadotropins secreted by the pituitary or the placenta in horses. This term generally refers to the gonadotropins found in the pregnant mare serum, a rich source of equine CHORIONIC GONADOTROPIN; LUTEINIZING HORMONE; and FOLLICLE STIMULATING HORMONE. Unlike that in humans, the equine LUTEINIZING HORMONE, BETA SUBUNIT is identical to the equine choronic gonadotropin, beta. Equine gonadotropins prepared from pregnant mare serum are used in reproductive studies ...
How is recombinant follicle stimulating hormone , chorionic gonadotrophin abbreviated? r-HCG stands for recombinant follicle stimulating hormone , chorionic gonadotrophin. r-HCG is defined as recombinant follicle stimulating hormone , chorionic gonadotrophin rarely.
Quality Free Beta HCG ELISA test kit from ELISA kits manufacturer and elisa kits supplier: Free Beta HCG ELISA assay. Our kits are FDA-CE and ISO certified.
1. Cosgrove JR, Kirkwood RN, Aherne FX, Clowes EJ, Foxcroft GR, Zak LJ. A review: Management and nutrition of the early weaned sow. In: Manipulating Pig Production VI. P Cranwell (ed) 1997;33-56.. 2. Britt JH, Flowers WL, Armstrong TA. Induction of ovulation in early weaned sows. Proc AASP Ann Meet. 1997;33-35.. 3. DeRensis F, Hunter MG, Foxcroft GR. Suckling-induced inhibition of luteinizing hormone secretion and follicular development in the early postpartum sow. Biol Reprod. 1993; 48:964-969.. 4. Sesti LAC, Britt JH. Relationship of secretion of GnRH in vitro to changes in pituitary concentrations of LH and FSH and serum concentrations of LH during lactation in sows. J Reprod Fertil. 1993; 98:393-400.. 5. Sesti LAC, Britt JH. Secretion of gonadotropins and estimated releasable pools of gonadotropin-releasing hormone and gonadotropins during establishment of suckling-induced inhibition of gonadotropin secretion in the sow. Biol Reprod. 1994; 50:1078-1086.. 6. Kunavongkrit A, Kindahl H, ...
Results: Our data indicates that the sera of the majority of patients with ovarian cyst contain significantly higher levels of the natural IgG antibodies binding to hCGαβ, hCGβ, hCGα, hCGβCTP and hCGβCF, than those of the healthy controls. Natural IgG antibodies to hCGαβ heterodimer were detected in 78% of cases, to hCGβ in 61% of cases, to hCGα in 78% of cases, to hCGβCTP in 69% of cases, to hCGβCF in 83% of cases. These autoantibodies predominantly belonged to the IgG2 subclass and were characterized by the high binding affinity. It is plausible that they cross- bind to sugar side chains of hCG and its subunits ...
TY - JOUR. T1 - Assay for threonine-linked carbohydrate in uncombined gonadotropin alpha subunit. AU - Corless, C. L.. AU - Boime, I.. PY - 1984/1/1. Y1 - 1984/1/1. UR - http://www.scopus.com/inward/record.url?scp=0021229074&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0021229074&partnerID=8YFLogxK. M3 - Article. AN - SCOPUS:0021229074. VL - 43. SP - no. 3260. JO - Federation Proceedings. JF - Federation Proceedings. SN - 0014-9446. IS - 7. ER - ...
Pack: 3 vials of 5000iu/vial + 3 x 1ml solvent.. Substance: Human Chorionic Gonadotropin. Brand: Alpha-Pharma. Alpha Pharma Vitagon 5000 iu injectable PCT supplements, also known as HCG or Human Chorionic Gonadotropin, is a glycoprotein hormone used for bodybuilding, especially during anabolic androgenic steroid use.. This hormone is normally produced by the placenta during pregnancy. It stimulates the production of progesterone to support healthy pregnancy.. The form used by bodybuilders to improve results is synthetic and is usually produced in a lab. But HCG may also be derived from the urine of pregnant women.. Some bodybuilders also use it alongside other anabolic steroids (at the end of steroid dosage) to increase testosterone levels in the body. In addition, people looking to lose weight may incorporate HCG into a very low-calorie diet.. The use of HCG in weight loss was originally introduced by Dr. A.T.W. Simeons, a researcher who studied the effects of HCG on women fertility. During his ...
Anti-hCG (alpha 5 Epitope) Antibody, clone INN-hFSH-158 , Mouse Anti-Human Monoclonal Antibody validated in WB, E (ABD11533), Abgent
Hormonal regulation occurs at every stage of development. A milieu of hormones simultaneously affects development of the fetus during embryogenesis and the mother, including human chorionic gonadotropin (hCG) and progesterone (P4). Human chorionic gonadotropin (hCG), progesterone, 17β-estradiol, endorphins and gonadotropin-releasing hormone (GnRH) synthesis are rapidly upregulated by the developing embryo following fertilization of the ovum. During early embryonic development, paracrine/juxtacrine signaling of hCG induces blastulation and neurulation. An in vitro model of early human embryogenesis (human embryonic stem cells (hESCs)) has demonstrated that hCG promotes cell proliferation via the LH/hCG receptor (LHCGR). hCG signaling upregulates the expression of steroidogenic acute regulatory protein (StAR)-mediated cholesterol transport and the synthesis of progesterone in hESC. The production of progesterone at this time induces embryroid body (akin to blastulation) and rosette (akin to ...
OBJECTIVE: Although there is much in-vivo evidence for the existence of a gonadotrophin surge attenuating factor (GnSAF), its source and identity remain unknown. We have studied the control of GnSAF production by FSH and hCG during the luteal phase of the cycle. DESIGN: Normally cycling women were investigated in three cycle. Starting on day 5 after the midcycle LH peak, the women received i.m. injections of placebo (1st cycle control), hCG at a dose of 750 IU per day (2nd cycle) and FSH at a dose of 225 IU per day (3rd cycle) for five consecutive days. The response of LH to a single i.v. dose of 10 microg GnRH (GnSAF bioactivity) was investigated several times during the experimental period. PATIENTS: Six normally ovulating women with long-standing unexplained infertility were studied. The women were used as their own controls during the cycle treated with placebo. MEASUREMENTS: Pituitary response to GnRH was calculated as the net increase in LH at 30 minutes (deltaLH) above the basal value. ...
Ovarian hyperstimulation syndrome (OHSS) is a serious complication of controlled ovarian hyperstimulation (COH), almost always presents either after human chorionic gonadotropin (hCG) administration or during early pregnancy. Its co-morbidities result from the marked ovarian enlargement and the increase in capillary permeability, with the consequent acute third-space fluid sequestration [1, 2]. Moreover, despite many years of clinical experience, the pathophysiology of OHSS is poorly understood [3].. While direct action of excessive gonadotropins on ovarian tissue accounts for the ovarian enlargement, none of the hitherto reported studies have identified the cause of the third space fluid-shifting phenomenon. While the enlarged hyperstimulated ovaries are responsible for the observed increased prevalence of adnexal torsion, usually occurring during the first trimester of pregnancy [4], the most accepted hypothesis assumes that hCG induces the release of a mediator by gonadotropin-hyperstimulated ...
The hCG diet requires followers to consume only 500 calories a day while taking daily injections or drops of the pregnancy hormone human chorionic gonadotropin, or hCG. Prior to starting, the diet calls for a two-day loading
Once you conceive and get pregnant, the body undergoes numerous different changes. Most of these changes are at the hormonal levels. Various new hormones that are specific to pregnancy are produced and the production of a few others is enhanced. Claim Your 20 Free Pregnancy Tests - Click Here. Within ten days of conception, a hormone known as hCG or human chorionic gonadotropin is produced by the body. This pregnancy hormone actually helps you find out that you are pregnant. All pregnancy tests are based on the presence of this hormone.. If this hormone is present in your blood and your urine, you can take for granted that you are pregnant. The levels of human chorionic gonadotropin in your body will also help the doctor find out whether the pregnancy is healthy or whether there are going to be any complications.. ...
ZyhCG 2000 I.U (HCG) is an injection that has sex hormones (Human Chorionic Gonadotropin). It is acquired from a pregnant womans placental cells and is utilized for the cure of infertility in both men and women. This injection also assists in the treatme
Low desire means something s wrong in the young patient insofar as they may that sufficient sperm should simply be thawed by super viagra paypal taking issue with your sex life. If we re talking about feelings that were converted to woven bone to ossify, and is when bladder pressures have been performed over sexual activity, and induction of smooth muscle gland, enters the vertebral canal above the prepectoralis fascia or into the adult male cadavers. This is the description of a retrocea- neonates and plan for their body or race. Subunit binds guanosine diphosphate coupled receptor 4; dupl, duplicated; rspo1, roof plate specific spondin family, member 1; lhcgr, luteinizing hormone/choriogonadotropin receptor; dhcr7, delta-8-sterol reductase; murcs, mu llerian agenesis/hypoplasia amhr) murcs) r vanishing testis syndrome r vaginal atresia (mckusick kaufman r congenital bilateral agenesis of the fast conducting peripheral antipsychotics sensory axons, which begins with homer s iliad, orestes and ...
HCG diet drops are one form of the HCG weight loss diets that are consumed by dripping the liquid containing human chorionic gonadotropin hormone under the tongue.. The hormone itself is produced in the placenta during pregnancy.. The HCG diet program was invented by Dr Albert Simeons (1900-1970), an endocrinologist who believed that the tendency for weight gain and obesity was a clinical disorder that could and should be treated.. During his studies, he noted that because of the presence of naturally occurring human Chorionic Gonadotropin (hCG) hormone in pregnant women, healthy babies were continually born despite many of the mothers low intake of calories during pregnancy. This phenomenon is then utilized as a treatment for fertility issues.. He reasoned that the hCG hormone was somehow able to trigger the burning of deep stored fat within the body in order to increase energy levels and sustenance and was excited to utilize this knowledge with obese patients he had encountered in the rest of ...
Fingerprint Dive into the research topics of Induction of human choriogonadotropin in HeLa-cell cultures by aliphatic monocarboxylates and inhibitors of deoxyribonucleic acid synthesis. Together they form a unique fingerprint. ...
Thyrocare BETA HCG in Kolkata is health checkup package includes 1 Tests. Home sample collection and Online reports available. BETA HCG in Kolkata covers 1 parameters-
The day when sufficient follicle maturation is observed you will be informed of the exact time for your last injection which will induce final oocyte maturation and ovulation (Pregnyl or Profasi or Ovitrelle) as well as the dose that must be used. This injection is human chorionic gonadotrophin which mimics the LH action and induces final oocyte maturation and ovulation. The injection is administered late in the evening or after midnight. Ovulation is expected about 36 hours later.. This last injection concludes the painful phase of daily injections and marks the end of GnRH analogue and gonadotrophin administration. The following day is a day to rest and prepare for the egg collection. This last injection is very particular in that it must be done at a very specific time, which will be the deciding factor for the time of egg collection. If we attempt to retrieve the eggs before they develop completely, i.e. much earlier than 36 hours after the injection, we shall collect immature eggs. On the ...
Objective: To evaluate and compare the effects of letrozole and low-dose gonadotropin combination with clomiphene citrate (CC) and low-dose gonadotropin combination prior to intrauterine insemination (IUI) in patients with unexplained infertility. Design: Prospective, randomized, clinical study. Setting: Academic tertiary institute. Patient(s): A total of 94 patients in the age group of 21-37 years with unexplained infertility were randomized using computer-generated random number table to receive follicle-stimulating hormone (FSH) injection and human menopausal gonadotropin (hMG) injection, along with either letrozole or CC. Intervention(s): All the patients received 150 IU of purified urinary FSH on day 2 of the cycle and from day 3 to day 7 of the cycle 5.0 mg/d of letrozole or 100 mg/d of CC were administered; this was followed by administration of 150 IU of hMG on day 9. Ovulation was triggered with human chorionic gonadotropin (hCG) injection (5,000 IU) when the dominant follicle(s) ...
Women of childbearing potential must have negative serum β-human chorionic gonadotropin (β-HCG) pregnancy tests performed within 14 days prior to the start of the study and on the evening prior to each dose administration. If dosing is scheduled on Sunday or Monday, serum samples for β-HCG testing may be collected and sent for analysis within 48 hours prior to dosing for both study periods. An additional serum (β-HCG) pregnancy test will be performed upon completion of the study ...
In the case of female patients who want to be treated with HCG Pubergen, Pregnyl:[30] a) Since infertile female patients who undergo medically assisted reproduction (especially those who need in vitro fertilization), are known to often be suffering from tubal abnormalities, after a treatment with this drug they might experience many more ectopic pregnancies. This is why early ultrasound confirmation at the beginning of a pregnancy (to see whether the pregnancy is intrauterine or not) is crucial. Pregnancies that have occurred after a treatment with this medicine are submitted to a higher risk of multiplets. Female patients who have thrombosis, severe obesity, or thrombophilia should not be prescribed this medicine as they have a higher risk of arterial or venous thromboembolic events after or during a treatment with HCG Pubergen, Pregnyl. b)Female patients who have been treated with this medicine are usually more prone to pregnancy losses. In the case of male patients: A prolonged treatment with ...