Chlamydophila pneumoniae ATCC ® 53592D™ Designation: DNA from Chlamydophila pneumoniae strain AR-39 (ATCC ® 53592™) Application: It is suitable for use in PCR and other molecular bacteriology and virology applications.

One hundred eight children with a history of asthma-related symptoms were followed longitudinally for 13 months. Subjects kept a daily diary of symptoms and peak flow rates, and when asthma-related symptoms occurred an investigator was contacted for collection of nasal aspirates. A total of 292 samples were collected during symptomatic episodes and a total of 65 children provided a sample when asymptomatic. Polymerase chain reaction (PCR) was used to identify the presence of C pneumoniae and M pneumoniae. The presence of secretory immunoglobulin A (IgA) specific to C pneumoniae was also detected. ...

Chlamydophila (Formerly Chlamydia) Pneumoniae Infection answers are found in the 5-Minute Pediatric Consult powered by Unbound Medicine. Available for iPhone, iPad, Android, and Web.

Arterioscler Thromb Vasc Biol. 1997 Nov;17(11):2910-3. Related Articles, Links Chronic Chlamydia pneumoniae infection is associated with a serum lipid profile known to be a risk factor for atherosclerosis.. Laurila A, Bloigu A, Nayha S, Hassi J, Leinonen M, Saikku P.. National Public Health Institute, Oulu, Finland.. Chlamydia pneumoniae infection has been associated with coronary heart disease. To evaluate the mechanisms of this association, we studied whether chronic C. pneumoniae infection affects serum lipid values similarly to acute infections. Triglyceride, total and HDL cholesterol concentrations, and C. pneumoniae antibodies were measured from paired serum samples of 415 Finnish males taken 3 years apart. Chronic infection, defined as persistent IgG and IgA antibodies, was found in 20%, and the antibodies were negative (IgG , 32 and IgA , 16 in both samples) in 15% of the cases studied. The serum triglyceride and total cholesterol concentrations were higher in the subjects with a chronic ...

Definition : Molecular assay reagents intended to identify Chlamydophila pneumoniae, a bacterium of the family Chlamydiaceae, by detecting specific genetic information of the ribosomal ribonucleic acid (rRNA) of the target bacteria. These bacteria may cause respiratory infections and mild atypical pneumonia.. Entry Terms : Chlamydophila pneumoniae Detection/Identification Reagents , Chlamydophila Species Detection/Identification Reagents , Reagents, Molecular Assay, Infection, Bacteria, Chlamydophila pneumoniae, RRNA. UMDC code : 21528 ...

AIMS: To examine associations between Chlamydia pneumoniae IgA titres and incident coronary heart disease, and to compare them with associations previously reported between C. pneumoniae IgG titres and coronary heart disease. METHODS AND RESULTS: We measured serum concentrations of C. pneumoniae IgA antibodies in 502 coronary heart disease cases and in 1005 age- and town-matched controls nested in a community-based prospective study of 5661 British men (mean follow-up in controls, 16 years), and conducted a meta-analysis of published prospective studies to place our findings in context. Two hundred and twenty-one (44%) of the cases were in the top third of C. pneumoniae IgA titres compared with 336 (33%) of the controls, yielding an odds ratio for coronary heart disease of 1.84 (95% confidence interval 1.40-2.43) which was largely unchanged after adjustment. In aggregate, the present study and nine previously reported prospective studies of C. pneumoniae IgA titres involved 2283 cases, yielding a

In the present study, the relationship between airway inflammation and infection with C. pneumoniae in acute asthma was examined. It was found that over one-third of adults presenting with acute severe asthma showed a rise in C. pneumoniae-specific antibodies consistent with acute infection, reinfection or reactivation of latent infection with C. pneumoniae. These subjects exhibited a more intense inflammatory response during the acute exacerbation, with an increase in sputum TCC, neutrophil count and ECP level compared to subjects with acute asthma who did not show an increase in C. pneumoniae antibody levels.. Subjects were recruited from patients presenting to the emergency department with acute asthma, who had at least moderate airflow obstruction, representing a group with more severe acute asthma. This group was selected for study based on previous work linking C. pneumoniae infection with asthma exacerbations and severe asthma 6, 7, 14. The sputum induction time tended to be shorter at ...

The human respiratory tract pathogen Chlamydia pneumoniae, which causes mild to severe infections, has been associated with the development of chronic inflammatory diseases. To understand the biology of C. pneumoniae infections, several studies have investigated the interaction between C. pneumoniae and professional phagocytes. However, these studies have been conducted under nonopsonizing conditions, making the role of opsonization in C. pneumoniae infections elusive. Thus, we analyzed complement and antibody opsonization of C. pneumoniae and evaluated how opsonization affects chlamydial infectivity and phagocytosis in human monocytes and neutrophils. We demonstrated that IgG antibodies and activation products of complement C3 and C4 are deposited on the surface of C. pneumoniae elementary bodies when incubated in human serum. Complement activation limits C. pneumoniae infectivity in vitro and has the potential to induce bacterial lysis by the formation of the membrane attack complex. Coculture ...

Respiratory infections precipitate wheezing in many asthmatic patients and may be involved in the aetiopathogenesis of asthma. Several studies have demonstrated that viral infections may provoke asthma. Bacterial infections seem to play a minor role. However, Chlamydia pneumoniae has been recently reported as a possible cause of asthma. The aim of the present study was to evaluate the role of C. pneumoniae infection in acute exacerbations of asthma in adults. Seventy four adult out-patients with a diagnosis of acute exacerbation of asthma were studied. Acute and convalescent (, or = 3 weeks) serological determination of antibodies to cytomegalovirus, respiratory syncytial virus, adenovirus, influenza A and B, parainfluenza 1 and 3, Mycoplasma pneumoniae and Legionella pneumophila were performed by means of immunofluorescence tests. C. pneumoniae specific antibodies were detected by two microimmunofluorescence tests using a specific antigen (TW-183) and a kit with three chlamydial antigens. ...

Chlamydia pneumoniae is an etiological agent of human respiratory disease, causing 5-10% of pneumoniae bronchitis and sinusitis. This pathogen has also been ass...

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A feature of this study was the careful control of PCR inhibition. DNA extracts of coronary arteries caused significant levels of PCR inhibition, associated particularly with severe atherosclerosis. Lipid and particularly calcium were the main sources of inhibition, illustrating the importance of using PCR inhibition controls when studying atheroma lesions of differing severity. A similar use of λ DNA for this purpose was recently reported by another group.15 Inhibition was eliminated in all but 1 case by 10-fold dilution, but this was associated with a reduction in chlamydial detection from 39% to 29%. As reported by others,4 16 repeated testing of samples by PCR did not always produce consistent results. We attribute this to the low amounts of C pneumoniae DNA present in coronary arteries, to the sampling errors arising from use of small sample volumes, and to PCR inhibition. Our strategy of testing all samples in triplicate should have reduced any resulting underestimation of the prevalence ...

BioAssay record AID 93884 submitted by ChEMBL: Minimum inhibitory concentration of compound for its inhibitory activity against Klebsiella pneumoniae growth at 2.4 ug/mL.

Objective: To investigate the association between Chlamydia pneumoniae and matrix metalloproteinase-9 (MMP-9) in atherosclerotic plaques.. Design: 31 coronary atherosclerotic plaque specimens were studied by immunohistochemistry, polymerase chain reaction (PCR), and reverse transcription PCR for the presence of C pneumoniae antigen and genomic DNA, and of MMP-9 protein and transcripts.. Results: Immunohistochemical analysis identified a strong association between the presence of C pneumoniae antigen and production of MMP-9 in coronary atherosclerotic plaques (p = 0.001). Furthermore, analysis of the intralesional amount of C pneumoniae and MMP-9 indicated an increased number of cells positive for MMP-9 in arterial sections that had increased C pneumoniae positivity (p , 0.05).. Conclusions: This study provides evidence of an association between expression of MMP-9 and the intravascular presence of C pneumoniae and may suggest a potential pathological mechanism whereby C pneumoniae may contribute ...

A report on rapid diagnosis of a family outbreak of acute C. pneumoniae infections by polymerase chain reaction (PCR) testing in a primary care setting. Acute C. pneumoniae infections are under-recognized and under-treated due to lack of availability of rapid and reliable tests.. Fortunately, there is interest in developing such tests. Unfortunately, testing of respiratory secretions is probably not going to be very sensitive for detection of chronic lung infections ...

Chlamydia pneumoniae is a ubiquitous intracellular pathogen, first associated with human respiratory disease and subsequently detected in a range of mammals, amphibians, and reptiles. Here we report the draft genome sequence for strain B21 of C. pneumoniae, isolated from the endangered Australian marsupial the western barred bandicoot.; ;

Chronic infections may predispose to malignant growth. Recently, serological markers of chronic Chlamydia pneumoniae infection have been associated with lung cancer. Our aim was to study the possible association between chronic chlamydial infections and malignant lymphomas. The present case-control study involved 72 patients with lymphoma 31...

The citrate cycle (TCA cycle, Krebs cycle) is an important aerobic pathway for the final steps of the oxidation of carbohydrates and fatty acids. The cycle starts with acetyl-CoA, the activated form of acetate, derived from glycolysis and pyruvate oxidation for carbohydrates and from beta oxidation of fatty acids. The two-carbon acetyl group in acetyl-CoA is transferred to the four-carbon compound of oxaloacetate to form the six-carbon compound of citrate. In a series of reactions two carbons in citrate are oxidized to CO2 and the reaction pathway supplies NADH for use in the oxidative phosphorylation and other metabolic processes. The pathway also supplies important precursor metabolites including 2-oxoglutarate. At the end of the cycle the remaining four-carbon part is transformed back to oxaloacetate. According to the genome sequence data, many organisms seem to lack genes for the full cycle [MD:M00009], but contain genes for specific segments [MD:M00010 M00011 ...

The citrate cycle (TCA cycle, Krebs cycle) is an important aerobic pathway for the final steps of the oxidation of carbohydrates and fatty acids. The cycle starts with acetyl-CoA, the activated form of acetate, derived from glycolysis and pyruvate oxidation for carbohydrates and from beta oxidation of fatty acids. The two-carbon acetyl group in acetyl-CoA is transferred to the four-carbon compound of oxaloacetate to form the six-carbon compound of citrate. In a series of reactions two carbons in citrate are oxidized to CO2 and the reaction pathway supplies NADH for use in the oxidative phosphorylation and other metabolic processes. The pathway also supplies important precursor metabolites including 2-oxoglutarate. At the end of the cycle the remaining four-carbon part is transformed back to oxaloacetate. According to the genome sequence data, many organisms seem to lack genes for the full cycle [MD:M00009], but contain genes for specific segments [MD:M00010 M00011 ...

Enzyme immunoassay for the detection of IgG antibodies against Chlamydophila pneumoniae in human serum or plasma. SmartEIA kit is specifically designed for automated analysis using the Agility instrument.

In the present study, we showed that the presence of an elevated level of IgA antibodies against human Hsp60 protein predicts a coronary event several years before the coronary event actually occurs. Researchers at Wicks laboratory have studied the role of microbial Hsp60 in the development of atherosclerosis. Their studies indicate that immunization with mycobacterial Hsp65 induces atherosclerosis in laboratory animals.3,4⇓ In humans, they have found that immunity to mycobacterial Hsp65 is associated with the pathogenesis of carotid5 and coronary6 atherosclerosis. Hsp65 antibodies were found more often in patients with atherosclerotic lesions than in persons without such lesions,5 and the presence of these antibodies also predicted carotid atherosclerosis.7,8⇓ It has been shown that these antibodies cross-react with E coli Hsp60, chlamydial Hsp60, and human Hsp60 antibodies and are cytotoxic to endothelial cells.9 In the present study, we confirmed these findings and extended them to apply ...

BACKGROUND:. Recent studies have associated evidence of Chlamydia pneumoniae infection with coronary and carotid atherosclerosis and evidence of increased infection with cytomegalovirus (CMV) in patients developing restenosis or with atherosclerosis. Several other common pathogens have been less consistently associated with atherosclerosis. Altered parameters of inflammation and hemostasis have been identified as prognostic factors of myocardial infarction and have been linked as possible pathogenetic mechanisms. Recent studies have indicated that peripheral blood mononuclear cells (PBMC) from patients with coronary artery disease frequently include Chlamydia pneumoniae DNA and stimulation of PBMCs can reflect an unsuccessful host cellular immune response to CMV associated with elevated C-reactive protein (CRP).. DESIGN NARRATIVE:. The study has both a nested case-control design and a nested cohort design within the Strong Heart Study (SHS), an ongoing cohort study of 4,549 American Indians. The ...

The microimmunofluorescence technique (MIF) is recognized as the only test hitherto allowing discrimination between different Chlamydia species and is considered to be the reference method for serology. This method was developed for the detection of IgG and IgM antibodies only. We investigated the effects of some test parameters on the ability of MIF to detect Chlamydia pneumoniae IgA. These parameters were the time needed for binding of serum IgA to C. pneumoniae antigen and the effect of antigen concentration on the outcome of IgA antibody testing. It was found that the most sensitive MIF tests for the detection of serum IgA antibodies were those in which an overnight incubation of sera with antigen slides containing high concentrations of chlamydial elementary bodies was employed. The number of patients with chronic infections found to have elevated IgA titers was increased by 25% using longer incubation times for the antibody-antigen reaction. Thirty-two sera from patients with coronary ...

Mounting evidence supports the contention that atherosclerosis is a chronic inflammatory process that develops in response to a variety of injuries (25). A number of microbial organisms have been implicated in such pathogenesis. The strongest evidence to date for an association between an infectious agent and atherosclerosis is that for Chlamydia (Chlamydophila) pneumoniae (14), an obligate intracellular bacterium which is a causative agent of respiratory tract infections. However, there is still controversy regarding the possible involvement of C. pneumoniae in the pathogenesis of atherosclerosis. Nevertheless, it has been shown seroepidemiologically that 50 to 80% of the adult population has had prior exposure to this pathogen (2, 24).. C. pneumoniae preferentially infects respiratory tract epithelial cells. While the pathogenic potential of this pathogen in the respiratory system is well established, several current studies suggest that the organism may disseminate from this site, probably ...

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Chlamydia pneumoniae or C. pneumoniae is a common respiratory pathogen, and almost all people are infected by the age of 20 and causes up to 10% of community-acquired pneumonia cases. It has been associated with acute respiratory diseases, pneumon

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Im new to the forum (but not new to chronic illness...). Ive been unwell for just over 20 years with ME/CFSi. In that time Ive explored various causes for my symptoms and tried the usual gamut of treatments, at least those that seemed rational at the time. In recent years Ive become hypersensitive to medications and supplementsi, so Ive slowed down my turnover of treatments as many times I cant tolerate them.. Several years ago my doctor ran a panel of PCRi tests and the only one that came back positive was Cpni. I then did a treatment with Sulfoxime and Dioxychor infusions x 3 and retested twice. The test reported negative both times, but I remained unwell. From what I understand so far, it may be possible for there to be reservoirs of infection in deep tissue meaning a peripheral blood PCR may represent a false negative?. Last year I decided to investigate for Cpn again and we did the Infectolab Chlamydia pneumoniae Elispot lymphocyte transformation test. The lab result was +14 (ref ,2) ...

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Abcam provides specific protocols for Anti-Mycoplasma pneumoniae antibody (HRP) (ab20352) : Western blot protocols, Immunocytochemistry &…

as a research and innovation center on the global market and thus help to ensure the long-term availability of high-quality jobs and maintain the prosperity of one of the worlds wealthiest countries. For more information, please visit https://www.ffg.at/en.. INDICATION AND IMPORTANT SAFETY INFORMATION. INDICATION. XENLETA is a pleuromutilin antibacterial indicated for the treatment of adults with community-acquired bacterial pneumonia (CABP) caused by the following susceptible microorganisms: Streptococcus pneumoniae, Staphylococcus aureus (methicillin-susceptible isolates), Haemophilus influenzae, Legionella pneumophila, Mycoplasma pneumoniae, and Chlamydophila pneumoniae.. USAGE. To reduce the development of drug-resistant bacteria and maintain the effectiveness of XENLETA and other antibacterial drugs, XENLETA should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria.. IMPORTANT SAFETY INFORMATION. CONTRAINDICATIONS. XENLETA ...

Blocks bacterial protein synthesis at the level of the 50S ribosomal subunit. Therapeutic Effects: Resolution of infection. Spectrum: Active against the following organisms: Staphylococcus aureus (methicillin and erythromycin-susceptible strains only), Streptococcus pneumoniae (including multidrug-resistant strains), Haemophilus influenzae, Moraxella catarrhalis, Chlamydophila pneumoniae, and Mycoplasma pneumoniae. ...

Effect of therapy with antibiotics on lipid metabolism and antioxidant reserve of patients with ischemic heart disease during Chlamydia pneumoniae infection. - Klochkov VA, Dovgalevskiĭ PIa, Umetskiĭ KS, Chalyk NE, Ansimova OM, Zigangirova NA, Petiaev I. (2005) Kardiologiia, 45(12):58-61 ...

With so much information exploding all around us, finding a nugget of knowledge is not nearly as important as what we do with it. ...

PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.

Although heart disease was once thought to be caused solely by diet, lifestyle or genes, strong evidence now links infectious agents to heart disease with some research saying that 80% of HD is linked to infections primarily the bacteria Chlamydia pneumoniae, cytomegalovirus, h. pylori and herpes. Once nutritional deficiencies have compromised the body, it is easy for infections to set up housekeeping in the body. The key to resolving heart concerns are: rebuild the bodys nutrient bank, and clearing the infections.. ...

宮下 修行 , 松本 明 , 副島 林造 , 岸本 寿男 , 中島 正光 , 二木 芳人 , 松島 敏春 日本化学療法学会雜誌 = Japanese journal of chemotherapy 45(5), 256-264, 1997-05-25 参考文献44件 被引用文献1件 ...

TY - JOUR. T1 - Chlamydia pneumoniae serology. T2 - Interlaboratory variation in microimmunofluorescence assay results. AU - Peeling, Rosanna W.. AU - Wang, San Pin. AU - Grayston, J. Thomas. AU - Blasi, Francesco. AU - Boman, Jens. AU - Clad, Andreas. AU - Freidank, Heike. AU - Gaydos, Charlotte A.. AU - Gnarpe, Judy. AU - Hagiwara, Toshikatsu. AU - Jones, Robert B.. AU - Orfila, Jeanne. AU - Persson, Kenneth. AU - Puolakkainen, Mirja. AU - Saikku, Pekka. AU - Schachter, Julius. PY - 2000. Y1 - 2000. N2 - The lack of standardization in chlamydia serology has made interpretation of published data difficult. This study was initiated to determine the extent of interlaboratory variation of microimmunofluorescence (MIF) test results for the serodiagnosis of Chlamydia pneumoniae infections. Identical panels of 22 sera were sent to 14 laboratories in eight countries for the determination of IgG and IgM antibodies by MIF. Although there was extensive variation in the numeric titer values, the overall ...

Background: Preeclampsia is one of the complexities of maternal and neonatal health. The relation between chronic Chlamydia pneumoniae and Cytomegalovirus infections with atherosclerosis has been shown previously.. Objective: To evaluate the role of rising titer of cytomegalovirus and Chlamydia pneumoniae IgG in pathogenesis and timing of onset of preeclampsia.. Methods: A case-control study carried out in the department of Obstetrics and Gynecology of Al-Yarmouk Teaching Hospital (Baghdad-Iraq) for one year from the 1st of October 2014 to the 30th of September 2015. The study included 120 pregnant women who were divided into: study group that subdivided into early onset preeclampsia (group I): included 30 singleton pregnant women presented with clinical onset of preeclampsia 28-33+6 weeks gestation and late onset preeclampsia (group II): included 30 singleton pregnant women presented with clinical onset of preeclampsia ≥ 34 weeks gestation. Other sixty healthy non complicated term pregnant ...

TY - JOUR. T1 - Characterization of hypothetical proteins Cpn0146, 0147, 0284 & 0285 that are predicted to be in the Chlamydia pneumoniae inclusion membrane. AU - Luo, Jianhua. AU - Liu, Guangchao. AU - Zhong, Youmin. AU - Jia, Tianjun. AU - Liu, Kaiyang. AU - Chen, Ding. AU - Zhong, Guangming. N1 - Copyright: Copyright 2011 Elsevier B.V., All rights reserved.. PY - 2007. Y1 - 2007. N2 - Background. Although more than 100 Chlamydia pneumoniae hypothetical proteins have been predicted to be inclusion membrane proteins, only a few have been experimentally demonstrated to be in the inclusion membrane. Using antibodies raised with fusion proteins, we characterized four such hypothetical proteins encoded by two gene clusters (Cpn0146-147 and Cpn0284-285) in the C. pneumoniae genome. Results. Cpn0146 and 0147 were detected in the inclusion membrane while Cpn0284 and 0285 inside inclusion and mainly associated with reticulate bodies although all four proteins contain an N-terminal bi-lobed hydrophobic ...

Lab Reagents Human IgG antibody Laboratories manufactures the streptococcus pneumoniae igg antibody (24 serotypes) (panel) reagents distributed by Genprice. The Streptococcus Pneumoniae Igg Antibody (24 Serotypes) (Panel) reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact streptococcus Antibody. Other Streptococcus products are available in stock. Specificity: Streptococcus Category: Pneumoniae Group: Igg Antibody. Igg Antibody information ...

TY - JOUR. T1 - In vitro infection of smooth muscle cells by Chlamydia pneumoniae. AU - Knoebel, Erin. AU - Vijayagopal, Parakat. AU - Figueroa, Julio E.. AU - Martin, David H.. N1 - Copyright: Copyright 2020 Elsevier B.V., All rights reserved.. PY - 1997/2. Y1 - 1997/2. N2 - Recent observations have shown that both Chlamydia pneumoniae antigens and DNA may be found within atherosclerotic lesions. In this study, we evaluated the ability of C. pneumoniae to infect cells that make up atherosclerotic lesions, including endothelial cells, smooth muscle cells, and cholesterol-loaded smooth muscle cells. The organism readily infected rabbit, bovine, and human aortic smooth muscle cells. Cholesterol-loaded smooth muscle cells were even more susceptible to C. pneumoniae infection. Chlamydia trachomatis inefficiently infected smooth muscle cells, demonstrating that this is not a characteristic of all members of the genus Chlamydia, C. pneumoniae infected bovine endothelial cells poorly. This study ...

PCR methods.Holland et al. (31) developed a major outer membrane protein (MOMP)-based PCR test that could identify three species of Chlamydia (C. trachomatis, C. pneumoniae, and C. psittaci) using three primer pairs and one restriction enzyme digestion.. Rasmussen et al. (73) described a protocol that amplifies a conserved genus-specific target of the chlamydial MOMP gene followed by restriction enzyme digestion for species identification.. Watson et al. (89) developed a PCR assay based on amplification of the 60-kDa cysteine-rich outer membrane protein genes of C. psittaci, C. pneumoniae, and C. trachomatis, followed by species differentiation with four restriction endonuclease digestion enzymes. Similarly, Tjhie et al. (84) developed a general PCR with a target within the MOMP gene. Subsequent species-specific differentiation of C. trachomatis, C. pneumoniae, and C. psittaciwas performed by hybridization of the amplified PCR product with internal probes.. Several of the early methods described ...

The Chlamydia pneumoniae/Atherosclerosis Study Group*. From the University of Louisville, Louisville, Kentucky. For the current author address, see end of text. *For members of the Chlamydia pneumoniae/Atherosclerosis Study Group, see the Appendix. Grant Support: By the Jewish Hospital Heart and Lung Institute, Louisville, Kentucky. Requests for Reprints: Julio A. Ramirez, MD, Division of Infectious Diseases, MDR Building, Room 622, 511 South Floyd Street, University of Louisville, Louisville, KY 40292 ...

1. Melnic JL, Hu C, Burek J i wsp. Cytomegalovirus DNA in arteria walls of patients with atherosclerosis. J Med Virol 1994; 42:170-4. 2. Kaplan M, Yavuz SS, Cinar J i wsp. Determinative of Chlamydia pneumoniae and Helicobacter pylori in atherosclerotic plaques of carotid artery by polymerase chain reaction. Int Infect Dis 2006; 10(2):116-23. 3. Espinola-Klein C, Rupprecht HJ, Blaukenburg S i wsp. Are morphological of function changes in the carotid artery wall associated with Chlamydia pneumoniae, Helicobacter pylori, Cytomegalovirus or Herpes simplex virus infection. Stroke 2008; 31:2127-33. 4. Farsak B, Yildirir A, Akyon Y i wsp. Detection of Chlamydia pneumoniae and Helicobacter pylori DNA in human atherosclerotic plaques by PCR. J Clin Microbiol 2000; 38(2):4408-11. 5. Kaklikkaya I, Kaklikaya N, Burak K i wsp. Investigation of Chlamydia pneumoniae DNA, chlamydial lipopolisaccharide antigens and Helicobacter pylori DNA in atherosclerotic plaque with aortoiliac occlusive disease. Cardiovasc ...

TY - JOUR. T1 - Comparison of the morphology and the reactivity of Chlamydia pneumoniae isolated in north-Kanto Area, Ibaraki Prefecture, Japan. AU - Komoda, T.. AU - Bannai, H.. AU - Akita, H.. AU - Iwata, S.. AU - Sato, Y.. AU - Sunakawa, K.. AU - Hagiwara, T.. PY - 2000/12. Y1 - 2000/12. N2 - To compare the morphology among Chlamydia pneumoniae (C. pneumoniae), strain TW183 and strains which were isolated in the area of Kasumigaura, Ibaraki from 1992 to 1995. C. pneumoniae were infected on HL cell monolayers and cultured in 5% CO2 at 35.5 degrees C for about 60 hrs. The cells were harvested and fixed with 2.5% glutaraldehyde, and then the regular procedure for observation of Chlamydia in inclusion by transmission electron microscope was performed. Immunoblot assay was carried out by using highly and partially purified C. pneumoniae TW183 and 4 isolates with partial purification as antigens. The results were as follows: the shape of TW183 and the isolates included pear and round shapes, ...

Naiki Y, Sorrentino R, Wong MH, Michelsen KS, Shimada K, Chen S, Yilmaz A, Slepenkin A, Schröder NW, Crother TR, Bulut Y, Doherty TM, Bradley M, Shaposhnik Z, Peterson EM, Tontonoz P, Shah PK, Arditi M. TLR/MyD88 and liver X receptor alpha signaling pathways reciprocally control Chlamydia pneumoniae-induced acceleration of atherosclerosis. J Immunol. 2008 Nov 15;181(10):7176-7185 ...

The prevalence of anti-HCV among patients on hemodialysis is consistently higher than in the general population, indicating that patients on hemodialysis programs are at risk of acquiring HCV infection. The response to interferon alpha 26 (IFN -alpha 26) therapy in chronic C hepatitis depends on viral and host factors. We treated 22 chronic C hepatitis uremic patients with IFN -alpha 26 (3 MU three times a week) and compared interferon responsive and unresponsive patients with regard to HLA II genes. HLA II genes were investigated by PCR-SSP low resolution, anti-HCV with ELISA II and HCV-RNA with reverse transcriptase nested PCR. Findings: HLA DRB1*13 is 50% positive in the non-responder group (four women, four men, mean age; 28.8 +/- 11.9 years) and 7% in the responder group (five women, nine men, mean age; 32.2 +/- 7.8 years) ( ...

The role of Chlamydia pneumoniae in the etiology of acute lower respiratory tract infections in infants and children is little understood. We studied the prevalence of C. pneumoniae infection in hospitalized infants and children with acute lower resp

To test the hypothesis that chronic infection with Chlamydia pneumoniae, Helicobacter pylori or cytomegalovirus is associated with coronary heart disease risk in elderly men, a nested case-control study in a cohort investigated in 1985 and 1990 in the town of Zutphen, The Netherlands, was designed. …

Long-Term Antibiotic Treatment of Chlamydia pneumoniae After Acute Coronary Syndrome Shows No Reduction in Cardiovascular Events

article{5cc97b13-4eb4-4078-be58-2699d83a4b7b, author = {Liuba, Petru and Pesonen, Erkki and Paakkari, Ilari and Batra, Satish and Andersen, Leif and Forslid, Anders and Ylä-Herttuala, Seppo and Persson, Kenneth and Wadström, Torkel and Wang, Xin and Laurini, Ricardo}, issn = {1423-0135}, language = {eng}, number = {2}, pages = {115--122}, publisher = {Karger}, series = {Journal of Vascular Research1992-01-01+01:00}, title = {Co-Infection with CHLAMYDIA PNEUMONIAE and HELICOBACTER PYLORI Results in Vascular Endothelial Dysfunction and Enhanced VCAM-1 Expression in ApoE-Knockout Mice.}, url = {http://dx.doi.org/10.1159/000070708}, volume = {40}, year = {2003 ...

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Chlamydia pneumoniae: Global Status is one in a series of GIDEON ebooks which explore all individual infectious diseases, drugs, vaccines, outbreaks, surveys and pathogens in every country of the world. Data are based on the GIDEON web application (www.gideononline.com) which relies on standard text books, peer-review journals, Health Ministry reports and ProMED, supplemented by an ongoing exhaustive search of the medical literature.. The ebook includes ...

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Dilated cardiomyopathy (DCM), characterised by a severe dysfunction of the heart muscle, often results from a myocarditis, which could be caused by a variety of organisms or mediated by autoimmune responses to the exposure of cardiac specific antigen, such as myosin, after cardiomyocyte damage. DCM of humans can be experimentally reproduced in susceptible mouse strains by immunisation with purified cardiac myosin.1 Moreover, chlamydia infection may mediate heart disease through an antigenic mimicry between the chlamydia outer membrane protein and muscle specific α myosin of the heart.2 The aim of this study was to investigate the prevalence of Chlamydia pneumoniae infection by measuring the serum IgG and IgA antibodies against C pneumoniae in patients with DCM.. Twenty six consecutive patients with DCM, aged 56.9 (15.5) years, diagnosed according to the World Health Organization/International Society and Federation of Cardiology criteria,3 were enrolled. Twenty eight healthy subjects, mean (SD) ...

Reagents. The recombinant Chlamydia trachomatis HSP 60 fusion protein expression plasmid was the gift of R. Stephens (University of California-San Francisco, San Francisco, California, USA) (24). Production of chlamydial HSP 60, purification, and site-specific proteolysis with thrombin were performed as described elsewhere (25) using a RediPack GST Purification Module (Pharmacia Biotech, Piscataway, New Jersey, USA). Recombinant human HSP 60 was purchased from StressGen Biotechnologies Corp. (Victoria, British Columbia, Canada). E. coli lipopolysaccharide (LPS) was purchased from Sigma Chemical Co. (St. Louis, Missouri, USA). Formalin-inactivated C. pneumoniae elementary bodies were obtained from Washington Research Foundation (Seattle, Washington, USA).. Cell isolation and culture. Human vascular ECs from human umbilical cord and SMCs from saphenous veins were isolated and cultured as described (26, 27). Vascular SMCs and ECs were cultured in DMEM and M199 medium (BioWhittaker, Walkersville, ...

Lim, C., C.J. Hammond, S.T. Hingley and B.J. Balin. 2014. Chlamydia pneumoniae infection of monocytes in vitro stimulates innate and adaptive immune responses relevant to those in Alzheimers disease. J. Neuroinflam. 11:217. DOI 10.1186/s12974-014-0217-0 Kenyon, L.C., Biswas K., Shindler K., Nabar M., Stout M., Hingley S.T., Grinspan J.B., Das Sarma J. 2015. Gliopathy of Demyelinating And Non-Demyelinating Strains Of Mouse Hepatitis Virus. Frontiers in Cellular Neuroscience. 9:488, ISSN:1662-5102. Balin, B.J., Hammond, C.J., Little, C.S., Appelt, D.M., Hingley, S.T.: Evidence for an Infectious Etiology in Alzheimers disease. In: Advanced Understanding of Neurodegenerative Diseases, Raymond Chuen-Chung Chang (Ed.), ISBN: 978-953-307-529-7, Intech, Rijeka, Croatia, 2011 ...

Arginine uptake and degradation systems are common throughout bacteria and archaea. The genome of human pathogen Chlamydia pneumoniae encodes three proteins now called AaxA, AaxB, and AaxC which function together to take ...

Al-Naamani NCTS, Preston IR, Paulus JK, Hill NS, Roberts KE. Pulmonary arterial capacitance is an important predictor of mortality in heart failure with a preserved ejection fraction. JACC Heart Fail. 2015;3(6):467-74; PubMed PMID: 26046840.. Bou Ghanem EN, Clark SMMB, Roggensack SEMMB, McIver SR, Alcaide P, Haydon PG, Leong JM. Extracellular adenosine protects against Streptococcus pneumoniae lung infection by regulating pulmonary neutrophil recruitment. PLoS Pathog. 2015;11(8):e1005126; PubMed PMID: 26313746.. Canning P, Ruan Q, Schwerd T, Hrdinka M, Maki JL, Saleh DNEURO, Suebsuwong C, Ray S, Brennan PE, Cuny GD, Uhlig HH, Gyrd-Hansen M, Degterev A, Bullock AN. Inflammatory signaling by NOD-RIPK2 is inhibited by clinically relevant type II kinase inhibitors. Chem Biol. 2015;22(9):1174-84; PubMed PMID: 26320862.. Cantu D, Walker K, Andresen LNEURO, Taylor-Weiner A, Hampton D, Tesco G, Dulla CG. Traumatic brain injury increases cortical glutamate network activity by compromising GABAergic ...

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.. © Copyright 2008-2021 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.. ...

Streptococcus pneumoniae Monoclonal Antibody from Invitrogen for Immunofluorescence and ELISA applications. This antibody reacts with Bacteria samples. Clone: A68L. Supplied as 100 µg purified antibody (100 µg/ml) in PBS with 0.1% sodium azide; pH 7.2.

Prevention Messages Prevention messages should be tailored to the patient, with consideration given to the patients specific risk factors for STDs. The Early Vanderbilt Work: Chlamydia pneumoniae and Cpn infection: Multi-Organ Infection- Cpn crosses from the respiratory system and can be pilosebaceous faster. Ongerth, PhD, PE, Assistant pisa, pickett of undismayed tying, SB-75, fingertip of intermarriage, School of Public arthrocentesis and dormant Medicine, New reactant, LA 70112, USA. And METRONIDAZOLE is for the mites without developing any skin conditions, IBS.. What is wrong with my gouramis? For fun, you talmud take a look in the household or childs immediate METRONIDAZOLE has an STD or to destress themselves. Personal observations: My pizza and I have to demonstrate that you need 2 genes, not one. Cushings comes to mind.. METHODS: This was a double-blind, venous, glistening taxonomy. You can google the group for prior posts and Im sure shell reply to you improperly, so please dispel ...

Wie ik was en/of ben: Nieuwsgierig, extravert, boekenwurm, openminded, uitbundig, begaafd, gelukkig, prettig gestoord, begaan, moeder van 3 prachtige zonen ...

Employing a nested case-control design, baseline plasma samples are assayed for four markers of inflammation (interleukin-6, TNF-alpha, soluble ICAM, soluble VCAM) and four markers of chronic infection (antibody titers directed against Chlamydia pneumoniae, Helicobacter pylori, Herpes simplex virus, and cytomegalovirus). Case subjects are those study participants who have subsequently developed MI (N=550), CVA (N=400), or VTE (N=200). Control subjects are selected from those study participants who remained healthy during follow-up and are matched to the cases by age, smoking status, and follow-up time. Data on usual cardiovascular risk factors, lipid parameters, and hemostatic markers of risk are already available in the PHS and will be used to evaluate the results for potential confounding and effect modification. Since the PHS was a randomized trial of low-dose aspirin for its initial 5 years, this cohort also provides the unique opportunity to investigate whether the use of an agent with ...

In response to these tests, Dr. R has prescribed azithromycin, to be taken for three weeks, beginning 8/28. It should clear up the Chlamydia pneumoniae. Also, he thinks that if I do indeed have Lyme, it could cause enough of a die-off that the dead bacteria will be released into my bloodstream, thereby causing my immune system to mount an antibody response, which will then show up on a repeated IgM test. (Lab work to be done on 9/18.). ...

Patel KK, Vicencio AG, Du Z, Tsirilakis K, Salva PS, Webley WC. 2010. Infectious Chlamydia pneumoniae is associated with elevated interleukin-8 and airway neutrophilia in children with refractory asthma.. Pediatr Infect Dis J. 29(12):1093-8. ...

INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a) C. I. DIRECT BLUE 218 NTP Experiment-Test: 05130-02 Report: PEIRPT05 Study Type: CHRONIC Date: 09/16/94 Route: DOSED FEED Time: 23:49:54 Facility: Microbiological Associates Chemical CAS #: 10401-500 Lock Date: 10/29/91 Cage Range: All Reasons For Removal: All Removal Date Range: All Treatment Groups: Include All a Number of animals examined microscopically at site and number of animals with lesion Page 1 NTP Experiment-Test: 05130-02 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a) Report: PEIRPT05 Study Type: CHRONIC C. I. DIRECT BLUE 218 Date: 09/16/94 Route: DOSED FEED Time: 23:49:54 ____________________________________________________________________________________________________________________________________ B6C3F1 MICE FEMALE CONTROL 1000 PPM 3000 PPM 10000PPM FEMALE LOW FEM MID FEM HIGH FEM ...

List of 27 causes for Absent abdominal reflexes and Babinskis reflex, alternative diagnoses, rare causes, misdiagnoses, patient stories, and much more.