Chief cell - Wikipedia
The gastric chief cell (also known as a zymogenic cell or peptic cell) is a cell in the stomach that releases pepsinogen and chymosin. Pepsinogen is activated into the digestive enzyme pepsin when it comes in contact with acid produced by gastric parietal cells. This type of cell also secretes gastric lipase enzymes, which help digest triglycerides into free fatty acids and di- and mono-glycerides. There is also evidence that the gastric chief cell secretes leptin in response to the presence of food in the stomach. Leptin has been found in the pepsinogen granules of chief cells. Gastric pit cells are replaced every 2-4 days. This high rate of turnover is a protective mechanism designed to protect the epithelial lining of the stomach from both the proteolytic action of pepsin and the acid produced by parietal cells. Gastric chief cells are much longer lived and are believed to differentiate from stem cells located higher in the gastric unit in the isthmus. These stem cells ...
Chief cell financial definition of chief cell
Definition of chief cell in the Financial Dictionary - by Free online English dictionary and encyclopedia. What is chief cell? Meaning of chief cell as a finance term. What does chief cell mean in finance?
Ink4a/Arf-Dependent Loss of Parietal Cells Induced by Oxidative Stress Promotes CD44-Dependent Gastric Tumorigenesis | Cancer...
Gastrointestinal malignancies are strongly linked to chronic inflammation (25-29). Gastric tumorigenesis in K19-Wnt1/C2mE mice was also recently shown to be suppressed by knockout of either TNFα or its receptor TNFR1, suggesting that TNFα-dependent inflammation plays a key role in the development of gastric cancer (30). Furthermore, the development of SPEM in response to acute parietal cell loss is dependent on the recruitment of macrophages to the gastric epithelium (31). Together, these findings suggest that inflammation triggers the histopathologic alterations of gastric epithelium that leads to tumor development. We have now shown that the inflammation-associated ROS plays a key role in the parietal cell loss that is an early and critical step in the development of SPEM, and the subsequent formation of gastric tumors. The accumulation of ROS triggers the p38MAPK-p16INK4a/p19ARF signaling pathway selectively in parietal cells and the consequent induction of parietal cell loss. In fact, ...
The effect of H. pylori eradication on meal-associated changes in plasma ghrelin and leptin | BMC Gastroenterology | Full Text
Appetite-reducing hormones, such as amylin, insulin, GIP, GLP-1, PP, and PYY, produced in the small intestine and pancreas are important in mammalian energy homeostasis, [32-35], as is leptin which is produced mostly by adipocytes, but also by gastric chief cells . Importantly, gastric oxyntic endocrine cells  account for 65-80% of the bodys total ghrelin production. H. pylori colonization status has been correlated with circulating and gastric mucosal leptin levels , and with gastric mRNA expression and plasma levels of ghrelin [9, 37]. We now identified substantial effects of H. pylori eradication on meal-associated changes in gastric hormones and energy balance, confirming and extending prior studies in a more rigorous manner [13, 38].. That H. pylori-positive and H. pylori-negative subjects had similar baseline digestive hormonal physiologies (Additional file 3, Table S4) may reflect the highly integrated cross-regulation of energy homeostasis,  and the long-term equilibria ...
What are the secretions of parietal and chief cells? | AnswersDrive
The two main types of exocrine secretory cells of the stomach are parietal cells and chief cells. Parietal cells secrete hydrochloric acid and chief cells secrete digestive enzymes such as pepsin.
The gastric epithelial progenitor cell niche and differentiation of the zymogenic (chief) cell lineage
In the mammalian gastrointestinal tract, the cell fate decisions that specify the development of multiple, diverse lineages are governed in large part by interactions of stem and early lineage progenitor cells with their microenvironment, or niche. Here, we show that the gastric parietal cell (PC) i …
Zymogenic cell definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. Look it up now!
Histology MCQs GIT Questions And Answers | Physiology Plus
...Histology MCQs GIT (Questions and Answers)...Which cells secrete hydrochloric acid? a. Parietal cells b. Oxyntic cells c. Chief cells d. Mucous neck cells
Navy Hails Cosby as Honorary Chief Petty Officer - GlobalDefence.net -Streitkräfte der Welt
Bill Cos-by is not just a come-di-an and an actor - although hes pret-ty good at both - hes also been a tire-less advo-cate for social respon-si-bil-i-ty and edu-ca-tion and a con-stant friend to the Navy, Mabus said. Last year was the high-est com-pli-ment Ive ever received -- being made an hon-orary chief pet-ty offi-cer, and now Dr. Cos-by -- youre about to get the same hon-or.. Cos-by holds a doc-tor of edu-ca-tion degree from the Uni-ver-si-ty of Mass-a-chu-setts.. Mabus and West placed chief pet-ty offi-cer anchors on Cos-by in front of a huge gath-er-ing of chief pet-ty offi-cers and oth-er sailors. West helped Cos-by don a chief hos-pi-tal corpsmans ser-vice dress blue jack-et, and Mabus pre-sent-ed Cos-by with the accom-pa-ny-ing visored hat.. I will tell to you like I tell all of our new chiefs … when I pin these anchors on you, your job isnt over and your jour-ney is just begin-ning, West said to Cos-by. There is no greater hon-or than hav-ing earned the title Chief - ...
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cell death, or apoptosis (Kerr et al., 1972; One part of proliferated epithelia migrates Wyllie et al., 1980; Thompson, 1995; Raff, 1998). This article will focus on the role of which line the foveolae (pits) and the consideration of gastric histology, which epithelia migrate downwards in the gastric differs in the four anatomical subsites of glands. In the antrum, they differentiate the stomach. These four zones, i.e. cardia, within few days to mucous-secreting cells forming the pyloric glands. In the fundus for the TNM classification system) (UICC, and corpus, they differentiate within few 1997) are lined by two basically different weeks to chief cells, parietal cells, and suspected precursor cells can be identified mucosa is characterized by rather straight, Proliferation kinetics of the gastric antral cells, chief (or zymogenic) cells, parietal have concentrated on proliferation of the 1997). A second type of mucosa is present foveloar epithelium (Lipkin et al., 1963; in the distal third ...
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Im from Fresno and was headed to Knotts Berry Farm when tragedy strike... read through much more Im from Fresno and was headed to Knotts Berry Farm when tragedy strikes!! motor vehicle troubles!!!! I Phone Chief Cell MEchanic and Ali picks up, discusses the car hassle with me and suggests, Im 25 minutes away but Ill be there in forty and itll be eighty bucks.. which came to my shock as I had been expecting to hear not less than $two hundred since it was after hrs. twenty minutes later on, Ali demonstrates up with his mobile garage and stuck the issue within just twenty minutes ...
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Xconomy: Ex-Nightstar Exec Ozden Joins Akouos as Chief Development Officer
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Chief Ombudsman commences two investigations into the Ministry of Health and its services for people with intellectual...
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G20 financial chiefs agree open trade is key to growth-Schaeuble
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The role and influence of the chief financial officer is undergoing a transformation, opening up new opportunities for finance...
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Chiefs are expected to decide the fate of the former Boca Juniors frontman in the near future, with the player currently undergoing a medical
Guest: How my role as The Aggies copy chief has influenced my perspective of UC Davis - The Aggie
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IMF chief claimed diplomatic immunity when arrested | Euronews
Fresh details about the arrest in New York of former IMF chief Dominique Strauss-Kahn have emerged. Transcripts released by the prosecutors reveal
PharmAthene Appoints Industry Leader Thomas R. Fuerst Chief Scientific Officer | FierceBiotech
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Industry Leader John Reynders Joins Moderna Therapeutics as Chief Information Officer | FierceBiotech
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Future FinTech Appointed Weicheng Pan as Chief Strategy Officer
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PowerDsine Announces Management Changes; Aviram Shemer Named Chief Financial Officer. - Free Online Library
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CableLabs Chief Bows Out | Light Reading
Dr. Richard Green is to retire in late 2009, meaning CableLabs will be seeking a new chief for the first time in its 20-year history
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LankaWeb - Sub-clusters emerged from Minuwangoda cluster: Epidemiology Chief
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Warner Bros chief Kevin Tsujihara steps down amid Charlotte Kirk affair scandal - ITV News
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Advantage Make Wilkinson Chief Operating Officer | Scoop News
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Club chief criticises anglers who used pier amid heavy waves - Shields Gazette
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