The gastric chief cell (also known as a zymogenic cell or peptic cell) is a cell in the stomach that releases pepsinogen[1] and chymosin. Pepsinogen is activated into the digestive enzyme pepsin when it comes in contact with acid produced by gastric parietal cells.[2] This type of cell also secretes gastric lipase enzymes, which help digest triglycerides into free fatty acids and di- and mono-glycerides.[3] There is also evidence that the gastric chief cell secretes leptin in response to the presence of food in the stomach. Leptin has been found in the pepsinogen granules of chief cells.[4] Gastric pit cells are replaced every 2-4 days. This high rate of turnover is a protective mechanism designed to protect the epithelial lining of the stomach from both the proteolytic action of pepsin and the acid produced by parietal cells.[5] Gastric chief cells are much longer lived and are believed to differentiate from stem cells located higher in the gastric unit in the isthmus.[1] These stem cells ...
Definition of chief cell in the Financial Dictionary - by Free online English dictionary and encyclopedia. What is chief cell? Meaning of chief cell as a finance term. What does chief cell mean in finance?
Gastrointestinal malignancies are strongly linked to chronic inflammation (25-29). Gastric tumorigenesis in K19-Wnt1/C2mE mice was also recently shown to be suppressed by knockout of either TNFα or its receptor TNFR1, suggesting that TNFα-dependent inflammation plays a key role in the development of gastric cancer (30). Furthermore, the development of SPEM in response to acute parietal cell loss is dependent on the recruitment of macrophages to the gastric epithelium (31). Together, these findings suggest that inflammation triggers the histopathologic alterations of gastric epithelium that leads to tumor development. We have now shown that the inflammation-associated ROS plays a key role in the parietal cell loss that is an early and critical step in the development of SPEM, and the subsequent formation of gastric tumors. The accumulation of ROS triggers the p38MAPK-p16INK4a/p19ARF signaling pathway selectively in parietal cells and the consequent induction of parietal cell loss. In fact, ...
Appetite-reducing hormones, such as amylin, insulin, GIP, GLP-1, PP, and PYY, produced in the small intestine and pancreas are important in mammalian energy homeostasis, [32-35], as is leptin which is produced mostly by adipocytes, but also by gastric chief cells [6]. Importantly, gastric oxyntic endocrine cells [36] account for 65-80% of the bodys total ghrelin production. H. pylori colonization status has been correlated with circulating and gastric mucosal leptin levels [9], and with gastric mRNA expression and plasma levels of ghrelin [9, 37]. We now identified substantial effects of H. pylori eradication on meal-associated changes in gastric hormones and energy balance, confirming and extending prior studies in a more rigorous manner [13, 38].. That H. pylori-positive and H. pylori-negative subjects had similar baseline digestive hormonal physiologies (Additional file 3, Table S4) may reflect the highly integrated cross-regulation of energy homeostasis, [39] and the long-term equilibria ...
The two main types of exocrine secretory cells of the stomach are parietal cells and chief cells. Parietal cells secrete hydrochloric acid and chief cells secrete digestive enzymes such as pepsin.
In the mammalian gastrointestinal tract, the cell fate decisions that specify the development of multiple, diverse lineages are governed in large part by interactions of stem and early lineage progenitor cells with their microenvironment, or niche. Here, we show that the gastric parietal cell (PC) i …
Zymogenic cell definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. Look it up now!
...Histology MCQs GIT (Questions and Answers)...Which cells secrete hydrochloric acid? a. Parietal cells b. Oxyntic cells c. Chief cells d. Mucous neck cells
Bill Cos-by is not just a come-di-an and an actor - although hes pret-ty good at both - hes also been a tire-less advo-cate for social respon-si-bil-i-ty and edu-ca-tion and a con-stant friend to the Navy, Mabus said. Last year was the high-est com-pli-ment Ive ever received -- being made an hon-orary chief pet-ty offi-cer, and now Dr. Cos-by -- youre about to get the same hon-or.. Cos-by holds a doc-tor of edu-ca-tion degree from the Uni-ver-si-ty of Mass-a-chu-setts.. Mabus and West placed chief pet-ty offi-cer anchors on Cos-by in front of a huge gath-er-ing of chief pet-ty offi-cers and oth-er sailors. West helped Cos-by don a chief hos-pi-tal corpsmans ser-vice dress blue jack-et, and Mabus pre-sent-ed Cos-by with the accom-pa-ny-ing visored hat.. I will tell to you like I tell all of our new chiefs … when I pin these anchors on you, your job isnt over and your jour-ney is just begin-ning, West said to Cos-by. There is no greater hon-or than hav-ing earned the title Chief - ...
Chief Keef Net Worth is $500 Thousand. Chief Keef net worth: Chief Keefs net worth is $500 thousand dollars. Chief Keef, also known as Keith Cozart, was born in Chicago, Illinois. He was arrested for aggravated unlawful use of a weapon, and put un
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cell death, or apoptosis (Kerr et al., 1972; One part of proliferated epithelia migrates Wyllie et al., 1980; Thompson, 1995; Raff, 1998). This article will focus on the role of which line the foveolae (pits) and the consideration of gastric histology, which epithelia migrate downwards in the gastric differs in the four anatomical subsites of glands. In the antrum, they differentiate the stomach. These four zones, i.e. cardia, within few days to mucous-secreting cells forming the pyloric glands. In the fundus for the TNM classification system) (UICC, and corpus, they differentiate within few 1997) are lined by two basically different weeks to chief cells, parietal cells, and suspected precursor cells can be identified mucosa is characterized by rather straight, Proliferation kinetics of the gastric antral cells, chief (or zymogenic) cells, parietal have concentrated on proliferation of the 1997). A second type of mucosa is present foveloar epithelium (Lipkin et al., 1963; in the distal third ...
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From chairman to chief of the National Guard Bureau, here are the current Joint Chiefs of Staff PositionName, group Chairman of the Joint Chiefs of Staff Gen. Joseph F. Dunford, Jr., U.S.
With great sadness, NHRA reported today that Mark Lyle, NHRAS Chief Starter, passed away unexpectedly this past Sunday. On behalf of NHRA and the entire drag racing community, we offer our condolences to all of Lyles family and friends.. Lyle had been Chief Starter for the NHRA Mello Yello Drag Racing Series since 2012. He was only the third Chief Starter in NHRA history, along with the late Buster Couch (1955-1996) and Rick Stewart (1996-2011). ...
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The Chief information officers (CIOs) in the IT department of any organization hold the highest positions. Currently, they are considered significant contributors to the company who backs the objectives and goals of the organization. Chief information officers have leadership and strategic dynamic role in an organization. In a company, they are in charge of all IT-related operations and also planning and implementing the strategies of using information technology. The Australian New Zealand Standard Classification of Occupation (ANZCO) code contains info on the roles and responsibilities of various professions that are widely in the job market of Australia. Under code 135111of the ANZSCO defines job duties and responsibilities for the Chief Information Officer. The information provided can be used by any candidate who is willing to migrate as ICT professionals to Australia. Candidates can select the code for their ACS RPL report if the duties of the candidate are following those stipulated by ...
Im from Fresno and was headed to Knotts Berry Farm when tragedy strike... read through much more Im from Fresno and was headed to Knotts Berry Farm when tragedy strikes!! motor vehicle troubles!!!! I Phone Chief Cell MEchanic and Ali picks up, discusses the car hassle with me and suggests, Im 25 minutes away but Ill be there in forty and itll be eighty bucks.. which came to my shock as I had been expecting to hear not less than $two hundred since it was after hrs. twenty minutes later on, Ali demonstrates up with his mobile garage and stuck the issue within just twenty minutes ...
Anne de Graaf is UvAs Chief Diversity Officer. Together with Diversity Officers from each faculty, she is a key player in shaping diversity policy at the UvA while working to promote equality, inclusion and diversity within the university. The Chief Diversity Officer is appointed for a term of three years. In September 2020, her appointment was extended for another three years.
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Rabia Ozden has joined Akouos as chief development officer. She was most recently the chief medical officer of gene therapy developer Nightstar
WASHINGTON, Oct. 27, 2011 - The vice chiefs of the ser-vices told Con-gress mem-bers today that they fear bud-get cuts could cause a hol-low force. The men said they under-stand that the ser-vices face a lean time, but they asked the House Armed Ser-vices Committees readi-ness sub-com-mit-tee to be judi-cious about cuts. Gen. Peter W. Chiarel-li, the Armys vice chief of staff, asked the rep-re-sen-ta-tives to remem-ber that the ser-vices have fought a 10-year war, with an all-vol-un-teer force. That force is amaz-ing-ly resilient, but at the same time, it is strained, he said. Its equip-ment is strained, sol-diers are strained, fam-i-lies are strained. But theyve been absolute-ly amaz-ing over these 10 years at war. Chiarel-li said he under-stands bud-get cuts and cor-re-spond-ing force reduc-tions have to be made. How-ev-er, we must make them respon-si-bly so that we do not end up with either a hol-lowed out force … or an unbal-anced force, he said. The Army con-tin-ues to look for ...
Suleiman Hassan Ali, Chief Registrar, Amoud University, Amoud University Office of The Chief Registrar Main Campus, Amoud University, Amoud Valley, Borama, Awdal Email: [email protected]
Now Hiring Chief Xperience Officer For the last three years the fastest growing C level position in the corporate world is CCO Chief Customer Officer, also known as the CXO.
Ron Klain of Chevy Chase, who was chief of staff for President-elect Joe Biden when he was vice president, will be Bidens chief of staff again.
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Several hundred people gathered yesterday afternoon at the Hopewell Township Municipal Building to wish Hopewell Township Police Chief Lance Maloney a healthy and well deserved retirement. Chief Maloney has served the department for over 26 years.. ...
Seventh Judicial Administrative District Chief Judge Robert P. VanDeHey has been elected chairman of the Committee of Chief Judges.
Gerresheimer AG - Düsseldorf (ots) - Dr. Bernd Metzner (48) is to become Chief Financial Officer of Gerresheimer AG, taking up office at the latest on July 1, 2019. Dr. Bernd Metzner has been Chief Financial Officer of SDAX-listed Ströer SE & ...
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by DigitalPh33r Bungie has given Master Chief the secret Recon armor thanks to the Arbiter, but the Chief has developed a terrible attitude as a result, and unleashes it by doing something terrible.
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The Chief Ombudsman Peter Boshier has launched investigations into the Ministry of Healths oversight of facilities and services for intellectually disabled people with high and complex needs.
There was a broad consensus among G20 financial chiefs that open trade was key to strengthening economic resilience, German Finance Minister Wolfgang Schaeuble said on Saturday, downplaying the lack of a clear rejection of protectionism. Some members like France said they were frustrated by the
Invacare Corporation today announced the resignation of Senior Vice President and Chief Financial Officer Robert K. Gudbranson, who will be leaving the company to pursue a new opportunity, effective November 26, 2017.
Mick Mulvaney, the acting White House chief of staff, is facing accusations over his role in a failed real estate deal near Charlotte, N.C.
Agendia Appoints Peter W. Schineller as Chief Commercial Officer Veteran Diagnostics and Biotech Executive to Lead Global Commercialization IRVINE, Calif. and AMSTERDAM, June 3, 2013 /PRNewswire/...
Future FinTech Group Inc. (NASDAQ: FTFT) (hereinafter referred to as "Future Fintech", "FTFT" or "Company" ) a leading blockchain e-commerce company and a service provider for financial technology, today announced it has appointed Mr. Weicheng Pan as Chief Strategy Officer
Industry Leader John Reynders Joins Moderna Therapeutics as Chief Information Officer CAMBRIDGE, Mass., May 22, 2013 /PRNewswire/ -- Moderna Therapeutics, the pioneering company developing messenger...
Read Warner Bros chief Kevin Tsujihara steps down amid Charlotte Kirk affair scandal latest on ITV News. All the Entertainment news
A year in reflection: What Ive learned from editing each and every Aggie article When I tell people that Im the copy chief at The Ca
Sheain Fernandopulle Courtesy The Daily Mirror There is always a possibility of sub-clusters emerging from the Minuwangoda main cluster and one has already been created from a private apparel factory in Katunayake, Chief Epidemiologist Dr Sudath Samaraweera said today. He told the media that each case reported daily was either directly or indirectly linked to […]
CAMBRIDGE, Mass., Jan. 9, 2014 /PRNewswire/ -- Zafgen Appoints Chief Commercial Officer and New Member of Board of Directors. - Industry Veterans Bring a...
The role and influence of the chief financial officer is undergoing a transformation, opening up new opportunities for finance professionals.
Few health organizations or consumers feel theyve achieved their goals of improved outcomes, lower cost and higher satisfaction. And clinicians are overwhelmed with administrative volume and complexity. A new role is needed to synchronize the needs of providers, health plans and patients - Chief Outcomes Officer ...
As the registration for the third phase vaccination, covering people between 18-44 years, has started today, Ram Sewak Sharma, Chief of CoWin portal where eligible people have to register themselves, said the government is expecting the daily registration numbers to double from the existing 50 lakhs.
SOUTH BEND, Ind., Jan. 22, 2013 /PRNewswire/ -- Press Ganey Names Christina Dempsey Chief Nursing Officer. Company Deepens Commitment to Improving the...
Chymosin /ˈkaɪməsɪn/ or rennin /ˈrɛnɪn/ is a protease found in rennet. It is an aspartic endopeptidase belonging to MEROPS A1 family. It is produced by newborn ruminant animals in the lining of the abomasum to curdle the milk they ingest, allowing a longer residence in the bowels and better absorption. It is widely used in the production of cheese. Bovine chymosin is now produced recombinantly in E. coli, Aspergillus niger var awamori, and K. lactis as alternative resource. Chymosin is produced by ruminant animals in the lining of the abomasum. Chymosin is produced by gastric chief cells in young ruminants and some other newborn animals to curdle the milk they ingest, allowing a longer residence in the bowels and better absorption. Some other non-ruminant species, including pigs, cats, and seals, produce it. One study reported finding a chymosin-like enzyme in some human infants, but others have failed to replicate this finding. Humans have a pseudogene for chymosin that does not generate ...
참고문헌 1: Goldenring & Nam. Prog Mol Biol Transl Sci (2010) Review; Oxyntic atrophy, metaplasia, and gastric cancer - Gastric carcinogenesis involves the loss of parietal cells (oxyntic atrophy) and subsequent replacement of the normal gastric lineages with metaplastic cells. In humans, two metaplastic lineages develop as sequelae of chronic Helicobacter pylori infection: intestinal metaplasia and spasmolytic polypeptide-expressing metaplasia (SPEM). Mouse models of both chronic Helicobacter infection and acute pharmacological oxyntic atrophy have led to the discovery that SPEM arises from transdifferentiation of mature chief cells. The presence of inflammation promotes the expansion of SPEM in mice. Furthermore, studies in Mongolian gerbils as well as increasing evidence from human studies indicate that SPEM likely represents a precursor for the development of intestinal metaplasia. These findings suggest that loss of parietal cells, augmented by chronic inflammation, leads to a cascade ...
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The balance of protective and aggressive factors in the gastric mucosal barrier is an important consideration in gastrointestinal diseases (4). Gastric acid, pepsin, and external stimuli are known aggravating factors of gastric mucosal cells, while microcirculatory system, HCO3−, prostaglandins, epidermal growth factor synthesis, and epithelial cell reconstitution are gastro-protective factors that maintain integrity of the gastric mucosal layer. Obviously, there are several viewpoints in association with the effect of ethanol on gastric mucosal cells. However, the main pathogenesis of ethanol-induced gastritis is vascular damage followed by mucosal cell-hypoxia, -degeneration, and -necrosis, respectively. The decline of anti-oxidant level and over production of oxygen free radicals especially super-oxide and hydrogen peroxide, are also link to ethanol-induced gastric injury and play a crucial role to further induce gastric inflammatory response. In addition, ethanol itself destroys gastric ...
Chief is a handsome wolf dog sold to a family by a breeder who represented him as a dog with no wolf content. Uneducated on the difficulties in caring for a wolf-dog, Chief pulled a Houdini and escaped his owners property by jumping the fence. A neighbor shot him, but luckily his injury caused him to lose only a toe and not his life. But after that, his owners knew he was unsafe and surrendered him to a foster who had experience caring for wolf dogs. While in foster care, Chief went to the vet to be neutered. Unfortunately, the vet found Chiefs left testicle in his abdomen beneath his bladder. Without surgery, the risk of Chief developing life-threatening cancer would be high. The Plan B Emergency Response Fund stepped in and paid for the advanced surgery required to remove both testicles. After an extended recovery due to the complexity of the surgery, Chief was successfully fostered, placed in a loving new home.. ...
Gulf Breeze P.D.-Chief Richard Hawthorne Lynn Haven P.D.-Chief Matthew E. Riemer Madison P.D.-Chief Reginald L. Alexander Maitland P.D.-Chief David Manuel Mascotte P.D.-Chief Eric ...
Supports expansion of global financial services products and solutions. Growing subscriptions to natural hazard data and analytics. Offering online solutions with three major industry partners DENVER, March 18, 2021 /PRNewswire/ - Intermap Technologies (Intermap or the Company), a global leader in geospatial intelligence solutions, today announced the hiring of a new Chief Technology Officer and expansion of its global financial services business.. Intermap is pleased to welcome Ralph Hope as Chief Technology Officer. For more than two years, Mr. Hope has been collaborating with the Companys technical teams and senior management as an analytics research consultant. Previously, Mr. Hope served as Chief Operating Officer and Chief Technology Officer for the Global Capital Markets division of BlackRock, one of the worlds largest and most respected asset managers with over $8 trillion in assets under management. In this role, Mr. Hope developed automatic allocation algorithms and global ...
Chiefs Rounds Presenter: Michele Markovitz, MD - Wills Eye Hospital Resident On Friday mornings at 7AM, tables are turned during Chiefs Rounds. Two cases are presented as unknowns by the residents to the Service Chiefs and Attending Staff. Chiefs Rounds provide a chance for the residents to see their Attending Staff think through the clinical presentation, differential diagnosis, and management of a difficult case. This approach invariably leads to a lively discussion among the staff and remains a vital teaching tool in resident education.. ...
Chiefs Rounds Presenter: Rebecca Soares, MD - Wills Eye Hospital Resident On Friday mornings at 7AM, tables are turned during Chiefs Rounds. Two cases are presented as unknowns by the residents to the Service Chiefs and Attending Staff. Chiefs Rounds provide a chance for the residents to see their Attending Staff think through the clinical presentation, differential diagnosis, and management of a difficult case. This approach invariably leads to a lively discussion among the staff and remains a vital teaching tool in resident education.. ...
But many, including Attawapiskat Chief Theresa Spence, who is on a liquids-only hunger strike, wanted a meeting with both Harper and Governor General David Johnston, and Atleo faced criticism, boycotts by chiefs from Manitoba and Ontario, and pressure from citizen protestors in the Idle No More movement.. In his statement, Atleo said First Nations citizens have just witnessed one of the most important chapters in our recent history.. Through the pressure of the grassroots, the sacrifices made by Chief Spence and her fellow strikers, and the work of many regional chiefs and the National Executive of the AFN, we have seized the attention of Canadians and of this government, he said. We forced open the door to the PMO and to the Governor-General. We achieved a commitment to the personal leadership of the Prime Minister, the Privy Council Office and other senior ministers. Now they know that the whole world is watching what progress we make. Now they understand the consequences of ...
NEW YORK (MarketWatch) -- Advanced Micro Devices Inc. AMD, -2.50% said Thursday that it has named Thomas Seifert to serve as its chief financial officer. The Sunnyvale, Calif.-based semiconductor maker said that Seifert, 46, succeeds Robert Rivet, who was promoted to chief operations and administrative officer. Seifert most recently worked at Qimonda, where he worked as chief operating officer and chief financial officer.. ...
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Army Chief General V K Singhs phenomenal record and leadership qualities could not prevent a number of controversies that marked his over two years stint as the Army Chief. Rediff.com takes a look. | FLASHBACK: The chequered stint of Army Chief Gen Singh
Following a nationwide search, Mass. Eye and Ear named Aalok Agarwala, MD, MBA, as Chief Medical Officer, and Kathrin Bourdeu, MD, PhD, as Chief of Anesthesia.
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Chief Direa is the sagely and elderly chief of Guldove in Chrono Cross. Raised and skilled in the ancient traditions of the Dragonians and her predecessors, she was versed in the legends of the Dead Sea and the Dragon God. After she became chief, she elected Steena as her assistant, and provided...
Cells with conspicuous eosinophilic cytoplasm and centrally located nuclei (sometimes paired) are the parietal cells (P in the figure above).. Cells with basal nuclei, basally basophilic cytoplasm, and apical vesicles are the chief cells (C in the figure above).. The glands are separated by thinner strands of lamina propria, visible as strands of denser, flattened or irregular nuclei. ...
Nearly a decade ago, a new organization of chief state school officers was charting new ground. The Education Leaders Council (ELC) was THE hip group to belong to. NCLB was the freshly minted law of the land. Chiefs, influencers, and vendors wanted to be part of the ELC posse, seeing the group as the drivers…
Horizon Media announced that it has elevated its Chief Financial Officer, Vincent OToole, to Chief Operating Officer. OToole will also retain his Chief Financial Officer title. Before his time at Horizon Media, OToole was Senior Vice President and Controller at MTV Networks. He has also held senior-level positions at Simon & Schuster Publishing, Paramount Communications and Arthur Andersen.. Federated Wireless, Inc., a subsidiary of Allied Minds (LSE: ALM), announced the appointment of John Brunoas Chief Financial Officer and Senior Vice President. Before joining Federated Wireless, John worked at VidSys. Prior to VidSys, John served as Chief Financial Officer for Appfluent Technologies. He also previously held executive positions at Access Spectrum, LLC, Ericsson IP Infrastructure, and Torrent Networking Technologies, Inc.. M.D.C. Holdings, Inc. (NYSE: MDC) announced that the Companys current Chief Financial Officer, John M. Stephens, is resigning effective May 22, 2015. Mr. Stephens has ...
Manufacturing giant Emerson announced the promotion of Vice President and Chief Compliance Officer Lisa Flavin to a senior vice president role. Flavin will also join Emersons office of the chief executive.
Halfpenny Technologies announced that Kirk Paul Kirkman has joined the company as its new Chief Revenue and Customer Experience Officer.. BLUE BELL, PA, UNITED STATES, February 13, 2018 /EINPresswire.com/ - Halfpenny Technologies, Inc., a recognized leader of clinical data exchange and business intelligence solutions, today announced that Kirk Paul Kirkman has joined the company as its new Chief Revenue and Customer Experience Officer. Effective immediately, in this newly created executive position, Kirk will oversee all aspects of Halfpenny Technologies sales, marketing, account management and customer relations teams.. When we created this new executive position, we sought a leader in the healthcare industry with the experience to support and drive the companys continued growth in the health plan, hospital, pharmacy, commercial laboratory and care coordination segments of the U.S. healthcare industry, said Tim Kowalski, president and CEO of Halfpenny Technologies. Kirk brings unique and ...
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Nigeria Chief of Defense Nigerias chief of defense staff Air Marshal Alex Badeh, centre, speaks during a demonstration calling on the government to rescue the kidnapped girls of the government secondary school in Chibok, in Abuja, Nigeria, Monday, May 26, 2014. Scores of protesters chanting Bring Back Our Girls marched in the Nigerian capital ...
Kaplowitz, who was named CEO of MEC N.A. eight months ago, said shes known Bamberger for more than 20 years, beginning when she was a DMB&B media planner on Procter & Gamble and he was a sales rep for Parade. Citing his expertise in integrated marketing, she said she was impressed with the path his career has taken since then. Hes taken some large interesting risks because of his curiosity, she said. He was very interested in social early on and figuring out where brands could fit in.. Before Dentsu, Bamberger was chief client officer at ad technology company, appssavvy. Prior to that job, he was executive vp of Katalyst, hired by co-founders Ashton Kutcher and Jason Goldberg. Earlier in his career, he worked on the publishing side when he worked at Meredith Corp. where his roles included the lead on Meredith 360 as chief innovation officer. Hes also held senior positions at Gruner & Jahr, USA and Time Warner Inc. where he worked with the companys The Parenting Group and Sports ...
Israeli bank chief blames slowdown on demography - AP News: JERUSALEM (AP) - Israels central bank chief says demographic changes .01/18/2018 3:59:21AM EST.
The average salary for a Chief People Officer with Full-Cycle Recruiting skills is $100,000. Visit PayScale to research chief people officer salaries by city, experience, skill, employer and more.
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Police chiefs radical drugs call The Chief Constable of Tayside Police has called for a radical approach in tackling drug-related...
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Bashaud Breeland vs Kenny Golladay: Chiefs Matchup. For this weeks Chiefs and Lions game, we look at the Bashaud Breeland vs Kenny Golladay matchup.