To study the macular sensitivity after half-dose verteporfin photodynamic therapy in patients with resolved central serous chorioretinopathy using the automated static perimeter. Prospective consecutive case study of 24 patients with resolved central serous chorioretinopathy was performed. The macular sensitivity was measured using a conventional automated static perimeter with the Swedish interactive threshold algorithm 10-2 and foveal threshold. Best corrected visual acuity, intraocular pressure, fundus examination, macular thickness, and volume were also examined. The mean macular sensitivities of the affected eyes and their normal fellow eyes were calculated and compared. P,0.05 was considered statistically significant. The mean macular sensitivities of the affected eyes were lower than the normal fellow eyes with a statistically significant difference in all areas of the study (P,0.05). Best corrected visual acuity improved significantly from pretreatment (0.26±0.3 logMAR) to posttreatment ...

Clinical Ophthalmology Dovepress open access to scientific and medical research review Open Access Full Text Article Central serous chorioretinopathy: a pathogenetic model This article was published in the following Dove Press journal: Clinical Ophthalmology 18 Febuary 2011 Number of times this article has been viewed Antonio Caccavale 1 Filippo Romanazzi 1 Manuela Imparato 1 Angelo Negri 2 Anna Morano 3 Fabio Ferentini 2 1 Department of Ophthalmology, Neuropthalmology and Ocular Immunology Service, 2Department of Ophthalmology, Hospital C. Cantù, Abbiategrasso, Milan, Italy; 3University Eye Clinic, Foundation IRCCS San Matteo Hospital, Pavia, Italy Abstract: Despite numerous studies describing predominantly its demography and clinical course, many aspects of central serous chorioretinopathy (CSCR) remain unclear. Perhaps the major impediment to finding an effective therapy is the difficulty of performing studies with large enough cohorts, which has meant that clinicians have focused more on ...

The presence of subretinal exudation in a patient with neurosensory detachment of the macula frequently suggests the diagnosis of choroidal neovascularisation. A retrospective chart review of newly diagnosed cases of central serous chorioretinopathy revealed 11 patients, seven men and four non-pregnant women, who had plaques of subretinal exudate, which presumably were fibrin. Each of these patients had a solitary plaque that ranged in size from 300 to 1500 microns in diameter. These patients had no signs or a clinical course suggestive of choroidal neovascularisation. In each case the subretinal plaque was overlying an exuberant leak in the retinal pigment epithelium. The exudate was generally present at the initial examination, and usually showed dissolution before or coincident with the resolution of the neurosensory detachment. After resolution of the central serous chorioretinopathy, patients were left with subtle alterations in the retinal pigment epithelium in the areas of the subretinal ...

TY - JOUR. T1 - Central serous chorioretinopathy in younger and older adults. AU - Spaide, R. F.. AU - Campeas, L.. AU - Haas, A.. AU - Yannuzzi, L. A.. AU - Fisher, Y. L.. AU - Guyer, D. R.. AU - Slakter, J. S.. AU - Sorenson, J. A.. AU - Orlock, D. A.. AU - Jampol, L. M.. PY - 1996/1/1. Y1 - 1996/1/1. N2 - Purpose: The purpose of the study is to investigate the demographic characteristics and clinical findings of central serous chorioretinopathy (CSC). Methods: This study examined a consecutive series of 130 patients with CSC seen over an 18-month period. Results: The mean age of the patients when examined was 51 years, and the male-to-female ratio was 2.6:1.0. A total of 62 patients were older than 50 years of age when first examined. Although the patients shared some clinical and angiographic similarities, the older patients had a lower mean visual acuity and were more likely to have diffuse retinal pigment epitheliopathy, bilateral involvement, and secondary choroidal neovascularization ...

TY - JOUR. T1 - Bilateral central serous chorioretinopathy in a patient treated with systemic cortico-steroids for non-Hodgkin lymphoma. AU - Bandello, F.. AU - Incorvaia, C.. AU - Rosa, N.. AU - Parmeggiani, F.. AU - Costagliola, C.. AU - Sebastiani, A.. PY - 2002. Y1 - 2002. N2 - PURPOSE. To describe the concomitant occurrence of systemic cortico-steroid treatment and the development of bilateral central serous chorioretinopathy (CSC), which promptly regressed after the reduction of the drug dosage, up to its scheduled withdrawal. METHODS. Case report. RESULTS. A 46-year-old white male, with a history of monolateral CSC, had a non-Hodgkin lymphoma on his right cheek. Soon after surgical excision of the tumoral lesion, he received a standard post-operative regimen of decreasing intramuscular betamethasone for 25 days, followed by 10 days withdrawal, then cycles of intravenous cyclophosphamide and vincristine, followed by 7-day oral prednisone, repeated monthly for three months. Fluorescein ...

TY - JOUR. T1 - Low-dose rifampin as maintenance therapy in chronic central serous chorioretinopathy. AU - Mattingly, Jeffrey J.. AU - Amram, Alec Lee. AU - El-Annan, Jaafar. PY - 2018/1/1. Y1 - 2018/1/1. UR - http://www.scopus.com/inward/record.url?scp=85040763872&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=85040763872&partnerID=8YFLogxK. U2 - 10.1016/j.jcjo.2017.11.019. DO - 10.1016/j.jcjo.2017.11.019. M3 - Article. C2 - 30340736. AN - SCOPUS:85040763872. JO - Canadian Journal of Ophthalmology. JF - Canadian Journal of Ophthalmology. SN - 0008-4182. ER - ...

A clinical research study published in The Lancet has reported that the treatment of eplerenone should be discontinued for the use of serous chorioretinopathy (CSCR) in ophthalmic practice. An analysis of the study reported that both primary and secondary outcomes of the trial indicated that there was no benefit of eplerenone treatment over placebo. Following the research, a commentary on the report stated that: This result is an important outcome that will change clinical practice. The trial results should prompt ophthalmologists to stop prescribing eplerenone to treat CSCR and encourage patients to participate in future trials of other potential interventions. The study was led by Prof. Andrew Lotery at the University of Southampton, and Prof. Sobha Sivaprasad at the Moorfields Eye Hospital NHS Foundation Trust, UK.. The aetiology of central serous chorioretinopathy (CSR) has an estimated 10 new cases per 100,000 men and 2 cases per 100,000 women in the population however, there is no clear ...

Purpose: To investigate the intrachoroidal structure in eyes with acute or chronic central serous chorioretinopathy (CSC) using spectral-domain optical coherence tomography (SD-OCT).. Methods: This retrospective observational case series involved 53 eyes of 51 patients (11 eyes of 11 females and 42 eyes of 40 males; mean age: 53.9 years) with CSC which had serous retinal detachment at the fovea. The clinical diagnosis of acute CSC was based on the duration of symptoms less than 6 months and the clinical findings on fluorescein angiography showing the typical pattern for one or several leakage points at the level of the retinal pigment epithelium. CSC cases other than acute CSC were categorized as chronic CSC. Eyes with a history of any other retinal diseases, a history of intraocular surgery or photodynamic therapy, a history of taking systemic corticosteroids, or high myopia (spherical equivalent less than minus 6 diopters or axial length longer than 26.5 mm) were excluded. The SD-OCT images of ...

Purpose : To investigate the changes in axial length (AL) and subfoveal choroidal thickness (SCT) after half-dose verteporfin photodynamic therapy (PDT) for central serous chorioretinopathy (CSC). Methods : This retrospective, observational case series involved 48 eyes (24 CSC eyes and 24 unaffected fellow eyes) of 24 patients (4 females and 20 males; mean age: 55.0+/-10.5 years) with unilateral CSC which showed the disappearance of serous retinal detachment after PDT. CSC was diagnosed using optical coherence tomography (OCT), fluorescein angiography, and indocyanine green angiography. The primary outcomes were the changes before and at 3-months after PDT in AL, SCT and spherical equivalent (SE) in the treated eyes and those in the unaffected fellow eyes. SCT was measured on enhanced depth imaging-OCT (EDI-OCT) images and AL was measured via partial coherence interferometry (IOLMaster; Carl Zeiss Meditec). Results : The mean AL in the treated eyes increased significantly from 23.85+/-1.11mm at ...

Purpose:. to evaluate the effectiveness as well as the detrimental influence of half-dose and half-fluence modification of verteporfin PDT for the treatment of prolonged unresolved Central Serous Chorioretinopathy (CSCR).. Study Design and Patient Recruitment:. This study was a prospective, randomized, consecutive, open-labeled, comparative interventional case series. Patients with symptomatic acute or chronic CSC of 3 weeks or more duration were recruited. Patients were offered treatment if they had worsening of symptoms or no subjective improvement since the onset of the CSC. Inclusion criteria included 1) patients with best-corrected visual acuity (BCVA) of 20/400 or better; 2) presence of subretinal fluid (SRF) and/or serous pigment epithelial detachment (PED) involving the fovea on optical coherence tomography (OCT); 3) presence of active angiographic leakage in fluorescein angiography (FA) caused by CSC but not CNV or other diseases; and 4) abnormal dilated choroidal vasculature and other ...

Changes of outer retinal microstructures after photodynamic therapy for chronic central serous chorioretinopathy Kimiko Shimizu,1 Yohei Hashimoto,1 Keiko Azuma,1 Yoko Nomura,1 Ryo Obata,1 Hidenori Takahashi,1,2 Yasuo Yanagi3,4 1Department of Ophthalmology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Tokyo, 2Department of Ophthalmology, Jichi Medical University, Tochigi, Japan; 3Singapore Eye Research Institute, Singapore National Eye Center, 4Ophthalmology and Visual Sciences Program, Duke-NUS Medical School, National University of Singapore, Singapore Purpose: To evaluate the morphological changes in retinal microstructures following modified photodynamic therapy (PDT) for chronic central serous chorioretinopathy. Subjects and methods: Retrospective study of 21 consecutive eyes (age, 59±8.0 years [mean ± SD]) of 21 patients with chronic central serous chorioretinopathy. Inner foveal thickness (the distance between the internal limiting membrane and external

Central serous chorioretinopathy (CSCR) is the fourth most common retinopathy after age-related macular degeneration, diabetic retinopathy and branch retinal vein occlusion.[1] CSCR typically occurs in males in their 20s to 50s who exhibit acute or sub-acute central vision loss or distortion. Other common complaints include micropsia, metamorphopsia, hyperopic (most common) or myopic shift, central scotoma, and reduced contrast sensitivity and color saturation.[2] No underlying pathophysiologic mechanisms have been proven, but CSCR is thought to occur due to hyper-permeable choroidal capillaries, which, in association with retinal pigment dysfunction, cause a serous detachment of the neurosensory retina. Recurrence occurs in about 31% patients with CSCR,[3] though the recurrence rate has been quoted to be up to 50% in most texts.

Objective: Central serous chorioretinopathy (CSC) is a retinal disorder characterized by an accumulation of serous fluid under the retina thought to be due to excessive choroidal hyperpermeability. The retinal pigment epithelium (RPE) plays a critical role in removing fluid from the subretinal space. This RPE pump is believed to be a key player in the reabsorption of subretinal fluid and maintenance of retinal attachment. Fluid transport assays have examined whether interferon gamma induces changes in fluid transport across human fetal RPE monolayers and showed an increase in fluid absorption from the retinal to the choroidal side of the tissue. An in vivo rodent model of retinal detachment has been used to measure the effect of interferon gamma on re-absorption following retinal detachment and showed that the addition of interferon gamma to the anterior eye surface caused a significant, rapid decrease in retinal detachment volume in the first hour of observation. This pilot study will ...

AimsTo investigate the prevalence of pachychoroid pigment epitheliopathy (PPE) in fellow eyes of patients with unilateral central serous chorioretinopathy (CSC) and to determine differences between patients with PPE, uncomplicated pachychoroid (UCP) and normal fellow eyes.MethodsWe retrospectively r

Background. To compare retrobulbar blood flow in patients with central serous chorioretinopathy (CSC) and healthy subjects using color Doppler ultrasonography. ...

A major interest in a well-known and not uncommon disorder of the macula is central serous chorioretinopathy. This is a disorder that occurs in young adults who under stress or who have a particular risk of leakage and swelling of the choroidal circulation, leading ultimately to detachment of the macula.. Numerous clinical features as well as imaging characteristics have been the subject of The Macula Foundation research in the past several decades. While the pathogenesis or precise causative factors are still poorly understood, The Macula Foundation investigators have reported on particular classifications, imaging features, and treatment modalities. It is the most common macular disorder that is seen beginning in young adulthood.. ...

Results A total of 30 eyes in 26 patients, most of whom had previous treatment for chronic CSC, were included with a mean follow-up period of 40.37±4.11 months. No changes in BCVA were noted (p=0.562). During the 3-year follow-up period with OCT-A, five eyes had SRF noted. The other 25 eyes remained SRF free throughout the course. Regarding the morphological changes, the size of CNV enlarged significantly (p,0.01); VD of CNV decreased significantly (p=0.01); and the number of CNV with visible core vessel significantly increased (p,0.01). A significant reduced SFCT was noted (p=0.02), while the CRT remained unchanged (p=0.855). ...

The SRDs were resolved in 26 (89.7%) eyes at 3 months after the hPDT. The mean CCT (P = 0.001), the total choroidal area (P = 0.001), and the hypo-reflective area (P = 0.003) of the whole choroid were significantly decreased from the baseline at 3 months. The hyperreflective area of whole choroid was not significantly changed during the study period (P = 0.083). The hyperreflective but not the hyporeflective area of the inner choroid was significantly decreased at 3 months (P = 0.001, P = 1.000, respectively). The hyporeflective but not the hyperreflective area of the outer choroid was significantly decreased at 3 months (P = 0.001, P = 1.000, respectively ...

The effect of eradicating Helicobacter pylori on idiopathic central serous chorioretinopathy patients Yalong Dang,1,2,* Yalin Mu,2,* Manli Zhao,2 Lin Li,3 Yaning Guo,4 Yu Zhu1,2 1Department of Ophthalmology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, Peoples Republic of China; 2Department of Ophthalmology and Visual Science, Yellow River Hospital of Henan University of Science and Technology, Sanmenxia City, Henan, Peoples Republic of China; 3Department of Ophthalmology, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang City, Henan, Peoples Republic of China; 4Gu-Cheng Eye Hospital, Xian City, Shanxi, Peoples Republic of China *These authors contributed equally to this work Purpose: To evaluate the effect of Helicobacter pylori (H. pylori) eradication on the remission of acute idiopathic central serous chorioretinopathy (ICSCR). Study design: A prospective, randomized, placebo-controlled study of 53 participants. Main outcome measure

A 37-year-old woman (gravida 2, para 1, abortus 0), following an uncomplicated pregnancy except for a history of insulin-dependent gestational diabetes with good glycaemic control and a local Varicella-Zoster infection which treated successfully, underwent elective caesarean section under spinal anaesthesia with bupivacaine hydrochloride (10mg). Surgery was uneventful and two healthy twin-girls were delivered. Corticosteroids were at no point given. Antibiotics were given intraoperatively. Four days after the caesarean section the patient experienced a sudden decrease of visual acuity combined with a central scotoma and metamorphopsia in her right eye. At presentation, best-corrected visual acuity of the right eye was 8/20 with metamorphopsia, a central scotoma in Amslers grid and blurred vision. Funduscopy of the right eye revealed a serous elevation of the macula (Figure 1). Fluorescein angiography (FA) disclosed three expanding points of fluorescein leakage at the foveolar avascular zone. ...

Choroidal vascular remodelling in central serous chorioretinopathy after indocyannie green guided photodynamic therapy with verteporfin: a novel treatment at the primary desease level. Chan, W-M.; Lam, D. S. C.; Lai, T. Y. Y.; Tam, B. S. M.; Liu, D. T. L.; Chan, C. K. M. // British Journal of Ophthalmology;Dec2003, Vol. 87 Issue 12, p1453 Aims: To evaluate the changes in the choroidal vasculature in central serous chorioretinopathy (CSC) after photodynamic therapy (PDT) with verteporfin and to assess its potential role as a treatment option. Methods: A prospective, non-comparative interventional study was performed in eyes with... ...

CSR is a fluid detachment of macula layers from their supporting tissue. This allows choroidal fluid to leak into the subretinal space. The buildup of fluid seems to occur because of small breaks in the retinal pigment epithelium. CSR is sometimes called idiopathic CSR which means that its cause is unknown. Nevertheless, stress appears to play an important role. An oft-cited but potentially inaccurate conclusion is that persons in stressful occupations, such as airplane pilots, have a higher incidence of CSR. The type A personality has also been linked to this condition. However, the statistics may be skewed by the fact that CSR often goes undiagnosed or misdiagnosed; airline pilots and so-called type A people are demonstrably exacting, demanding people with (certainly in the case of pilots) better-than-average vision. They are more likely than the general population to notice the sometimes-subtle degradation of vision caused by CSR and insist on a believable diagnosis of it. People who need ...

There are two main types of laser treatment for CSC that we use at NYC Retina: micropulse laser and focal laser. Both types of laser are safe and effective. There are a few key differences that we will discuss below. Micropulse laser is a shorter pulse of laser compared to conventional, continuous wave laser (focal).. The purpose of the laser is to stimulate the pigmented cells under the retina to reduce fluid leakage from the small blood vessels in the macula and facilitate the bodys removal of the excess fluid. If the fluid under the macula clears, the vision should improve.. Focal laser is a continuous pulse of laser as opposed to a micro pulse. This type of laser can be very effective in CSC when there is a clear, single leaking point or hot spot seen on the fluorescein angiogram. When focal laser treatment is successful, the fluid under the macula may clear leading to vision improvement. Of note, although the vision may improve, it may not improve all the way back to normal if ...

There is no known effective treatment for the disease. Laser photocoagulation, which effectively burns the leak area shut, is sometimes suggested. In many cases the leak is very near the central macula, where photocoagulation would leave a blind spot. Additionally, a better long term outcome has not been demonstrated with photocoagulation. So more often than not the condition goes untreated. Transpupillary thermotherapy has been suggested as a lower-risk alternative to laser photocoagulation in cases where the leak is in the central macula. Any ongoing corticosteroid treatment should be stopped. Additionally, a new anti-microbial treatment will likely be recommended soon in light of recent findings regarding Helicobacter pylori. CSR sufferers usually find their own ways to manage the condition, which may include stress reduction and changes in nutrition. ...

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PURPOSE: To report a case of bilateral serous macular detachment following laser in situ keratomileusis (LASIK). DESIGN: Observational case report. METHODS: A 33-year-old man presented with sudden decrease of vision in both eyes 4 days following uncomplicated LASIK in both eyes for spherical equivalent of +5.00 diopters sph in the right eye and +7.00 diopters sph in the left eye. Detailed history with ocular and systemic examination, fluorescein angiography, and optical coherence tomography were done. Retinal examination had a documentation of retinal pigment epithelium atrophy in the macular region in both eyes pre-LASIK. RESULTS: A diagnosis of central serous chorioretinopathy (CSCR) was made in both eyes, with multifocal alterations in the retinal pigment epithelium and a pocket of serous retinal fluid in the macular region confirmed on OCT. Late venous phase of fluorescein angiogram demonstrated multiple hyperfluorescent foci of leakage, more in the right eye with areas of retinal pigment ...

The macula in the left eye shows a small puddle of fluid involving the fovea. This represents a detachment of the neurosensory retina from the RPE. OCT confirmed this finding. These findings are classic for idiopathic central serous chorioretinopathy (ICSC), also called central serous retinopathy. ICSC typically occurs in 20- to 45-year-old males who exhibit type A personalities.1 Although our patient is age 50, it does not change our diagnosis; ICSC has been reported in patients as old as age 60.2 It occurs more commonly in males than females (a 10-to-1 ratio), and there is often a strong relationship between ICSC and emotional stress, although we do not know whether stress triggers the condition.1 Migraine headaches also have been associated with the onset of these neurosensory detachments. On examination, the macula usually exhibits a round or oval area of elevation of the neurosensory retina. This can be very subtle and easily missed if the detachment is small or if there is a very shallow ...

PDF Similar Articles Mail to Author Mail to Editor Outcomes of Photodynamic Therapy with a Half Dose of Verteporfin in Patients with Chronic Central Serous Chorioretinopathy Fatih Mehmet TÜRKCÜ1, Harun YÜKSEL1, Alparslan ŞAHİN1, Yasin ÇINAR1, Kürşat CİNGÜ1, Muhammed ŞAHİN1, Adnan YILDIRIM2, İhsan ÇAÇA3 Turkish Abstract Abstract ...

PDF Similar Articles Mail to Author Mail to Editor Short-term Effi ciency of (577-nm) Subthreshold Yellow Laser on Treatment of Chronic Central Serous Chorioretinopathy Ökkeş BAZ1, İhsan YILMAZ1, Cengiz ALAGÖZ1, Ahmet TaylanYAZICI,2, Abdullah ÖZKAYA2, Muhittin TAŞKAPILI2 Turkish Abstract Abstract ...

48-year-old man has had waxing and waning vision in the left eye for the last year from central serous retinopathy. OD is 20/16, OS is 20/16 - 2 months post PDT therapy with Visudyne ...

48-year-old man has had waxing and waning vision in the left eye for the last year from central serous retinopathy. OD is 20/16, OS is 20/30 ...

Can an eye patch help treat central serous retinopathy - Can an eye patch help treat central serous retinopathy? No. Csr is typically treated with a watch and wait approach. Occasionally laser can be used to hasten the recovery. New injectable drugs are also being explored.

Is Central Serous Retinopathy (CSR) the new carpal tunnel for a generation of over-stressed and over-loaded information workers who spend far too many hours per day staring at screens of varying dimensions?. Central serous retinopathy (or choroidopathy) is essentially a delamination of the retina when cellular layers that normally serve as a fluid barrier between the choroid and the retina begin to leak. This introduces a bubble or blister of fluid underneath the retina. This results in blurred and dimmed vision.. Although CSR is idiopathic, it has been linked to chronic stress, defined biochemically as elevated serum cortisol levels. This finding is corroborated by an increased incidence of CSR in those with Cushings Syndrome (chronic overexposure to elevated levels of cortisol.) Men are more often affected than women; with an age of onset between 20-50, averaging around 45.. Ive been having progressively worse vision problems since December that I had attributed to floaters or sleep ...

Central serous chorioretinopathy (CSCR) is a retinal disorder that has been linked to the systemic use of corticosteroids. Recently, it has also been reported after local corticosteroid administration.

Expertise, Disease and Conditions: Diabetic Macular Edema, Diabetic Retinopathy, Macular Degeneration, Macular Degeneration (Age-Related), Macular Disorders, Macular Holes, Macular Puckers, Medical Diseases of the Retina, Ophthalmology, Proliferative Vitreoretinopathy, Retinal Detachment, Retinal Specialist, Retinal Surgery, Retinal Vascular Disease, Retinal Vessel Occlusion, Surgical and Medical Diseases of the Retina, Surgical Diseases of the Retina, Vitreoretinal Diseases and Surgery ...

Expertise, Disease and Conditions: Central Serous Chorioretinopathy, Diabetic Macular Edema, Diabetic Retinopathy, Macular Degeneration (Age-Related), Macular Disorders, Macular Holes, Macular Puckers, Medical Diseases of the Retina, Ocular Trauma, Ophthalmology, Retinal Detachment, Retinal Specialist, Retinal Surgery, Retinal Vein Occlusion, Retinal Vessel Occlusion, Surgical and Medical Diseases of the Retina, Surgical Diseases of the Retina, Vitreoretinal Diseases and Surgery ...

Our understanding of pachychoroid disease has expanded greatly thanks to multimodal clinical imaging technologies. Cross-sectional and en face depth-resolved imaging, such as enhanced depth imaging (EDI) OCT, Swept-Source OCT (SS-OCT), and OCT angiography (OCTa), have enabled a deeper appreciation for the role of the choroid in a wide-range of macular disorders.. Pachychoroid disease is a phenotype encompassing a spectrum of macular conditions which manifest common choroidal findings, and includes pachychoroid pigment epitheliopathy, central serous chorioretinopathy, peripapillary pachychoroid syndrome and focal choroidal excavation. This phenotype of great clinical relevance in that it may predispose patients to macular neovascularization (pachychoroid neovasculopathy). Many patients with pachychoroid disease develop this type 1 neovascularization as a late-stage manifestation. In some eyes, these vessels may form a branching network that can give rise to aneurysmal type 1 neovascularization ...

To report the anatomic and functional outcome of intravitreal dobesilate to treat recurrent central serous chorioretinopathy (CSC). This is an interventional case report in which dobesilate was intravitreally injected in a case of recurrent CSC

An association between cataract surgery and uveal effusion was first described by OBrien in 1935. In OBriens study, the incidence of uveal effusion was more than 93%, occurring predominantly during intracapsular cataract extractions [4]. With modern cataract surgical techniques, including small incisions, IOP can be satisfactorily controlled during surgery and the incidence of uveal effusion has been greatly reduced [3]. Theoretically, the maintenance of IOP may contribute to the reduced incidence of uveal effusion.. Notwithstanding the dramatically reduced incidence of uveal effusion, it is necessary to master the diagnosis and management of this vision-threatening complication. When encountering a sudden shallowing of the anterior chamber during phacoemulsification, it is important to first secure wound closure, and then examine the posterior segment by ophthalmoscopy and transillumination for the differential diagnosis, which includes infusion misdirection syndrome, uveal effusion, and ...

Copyright : ? 2017 Indian Journal of Ophthalmology That is an open access article distributed beneath the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3. modifications near the excellent arcade [Fig. 1a]. Remaining eye demonstrated RPE atrophy with pigment epithelial detachment (PED) [Fig. 1b]. Fluorescein angiography (FA) of the proper eye demonstrated parafoveal telangiectatic vessels with leakage quality of parafoveal telangiectasia (PFT) along with early hyperfluorescence with past due leakage in the temporal margin from the fovea. Best eye Epothilone D also demonstrated focal drip near excellent arcade and multiple windowpane problems suggestive of central serous chorioretinopathy (CSCR) [Fig ?[Fig2a2a and ?andb].b]. FA from the remaining eye revealed windowpane problems, PED, and skin damage [Fig. 2c]. Spectral site optical coherence tomography (SDOCT) of the proper eye demonstrated subretinal hyperreflectivity with adjacent intraretinal edema suggestive of CNV [Fig. ...

Free subject headings]: photodynamic therapy , idiopathic CNV , haemangioma , choroidal malignant melanoma , uveitis , central serous chorioretionpathy , subfoveal choroidal neovascularization , central serous chorioretinopathy , ocular histoplasmosis syndrome , punctate inner choroidopathy , randomized clinical-trial , report no. 3 , verteporfin therapy , vasoproliferative tumors , multifocal choroiditis , intravitreal ...

Chief Executive Officer. Dr. Slakter joined Ohr as Chief Medical Officer in May 2014 and was appointed board member in January 2015. He was previously Chief Executive Officer and co-founder of SKS Ocular LLC. He is also the Founder and Director of the Digital Angiography Reading Center (DARC) in New York, which is the largest center for ocular image evaluation for clinical trials of posterior segment disease with over 900 certified clinical sites in over 44 countries worldwide. Dr. Slakter has been involved extensively in the design and application of new diagnostic and treatment modalities for ophthalmic diseases. He has played a major role in the discovery, development and commercialization of treatments for age-related macular degeneration, diabetic retinopathy, retinal vascular disease, central serous chorioretinopathy and other retinal diseases. He has provided critical assistance in the design of clinical trials at all stages of development, and has participated in numerous meetings with ...

Retinal, Disease, Risk, Risk Factors, Aged, Calcium, Treatment, Calcium Dobesilate, Diabetic Retinopathy, Role, Kinase, Protein Kinase, Cancer, Head, and Migration

Shrestha, Merina, 2012. Genetic basis for inherited eye diseases in dogs : a case study of pigmentary chorioretinopathy in Chinese Crested Dogs. Second cycle, A2E. Uppsala: SLU, Dept. of Animal Breeding and Genetics ...

CSC Mock Test : Prepare online for CSC Placement. Get Online Practice Test for CSC Preparation along with Interview and Technical questions.

Grey value correlation is generally considered not to be applicable to matching of images of different modalities. In this paper we will demonstrate that, with a simple preprocessing step for the Computed Tomography (CT) images, grey value correlation can be used for matching of Magnetic Resonance Imaging (MRI) with CT images. Two simple schemes are presented for automated 3D matching of MRI and CT neuroradiological images. Both schemes involve grey value correlation of the images in order to determine the matching transformation. In both schemes the preprocessing consists of a simple intensity mapping of the original CT image only. It will be shown that the results are insensitive to considerable changes in the parameters that determine the intensity mapping. Whichever preprocessing step is chosen, the correlation method is robust and accurate. Results, compared with a skin marker-based matching technique, are shown for brain images. Additionally, results are shown for an entirely new ...

A 42-year-old woman who presented to hospital with acute vision loss in her right eye was diagnosed with a benign tumour in her adrenal gland. Writing in BMJ Case Reports, clinicians described how the patient presented with a visual acuity of 6/36 in her right eye and 6/6 in her left eye. Investigations revealed an exudative retinal detachment in her right eye as well as a pigment epithelial detachment. The patient had multifocal central serous retinopathy in both eyes. The woman, who had hypertension and diabetes, was diagnosed with Cushing syndrome and a right adrenal aden ...

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In the current study, quantitative mapping of choroidal thickness and volume and qualitative analysis of choroidal vascular integrity showed loss of choroidal tissue including the choriocapillaris layer in the convalescent stage of VKH. Additionally, loss of the choriocapillaris and the thinning of the choroid in the sub-macula area correlated with increased duration of the disease, lower VA, and the presence of structural changes in the retina.. Normal sub-foveal choroidal thickness measured by SD-OCT ranges from 260 to 287 μm and varies by age, refractive error, and ethnicity [24-26]. Choroidal thickness varies based on the nature of posterior segment pathology as well. For instance, choroidal thickness increases in hyperopia [24], acute VKH [14, 15, 18], central serous chorioretinopathy [27, 28], and polypoid choroidal vasculopathy [29, 30]. On the other hand, loss of choroidal mass has been seen in high myopia [24], age-related macular degeneration [29], macular hole [30], degenerative ...

The definition of CMD was previously made for CSCR and AMD, but there has been no reported definition in DME. It is important to define CMD and identify the related features to have more information about the prognosis of edema and the benefit of treatment. It has been associated with poor visual acuity in CSCR, and is said to affect the need for treatment in AMD.5,6,7 Cyst formation begins with intercellular fluid accumulation. Coalescence of the extracellular fluid occurs due to the disruption of Müller cells, whose pump-like function keeps the macula dry.18 In the chronic stage, fluid accumulates intracellularly. The subsequent death of Müller cells and neuroglia results in the formation of large cystoid cavities.19 Otani et al.3 reported the acute and chronic morphologies of DME in an OCT-based study and stated that the disappearance of septa resulted in confluent large cysts which might fill all layers of the retina. Consistent with this pathogenesis, Yamomoto et al.20 found that eyes ...