Buy anti-Vaccinia Virus, A27L antibody, Mouse Vaccinia Virus, A27L Monoclonal Antibody (Clone 12K239) (MBS644440) product datasheet at MyBioSource, Primary Antibodies. Application: ELISA (EL/EIA),Immunofluorescence (IF)
These products are affinity-purified IgG antibodies that recognize the heavy and light chains (H+L) of rabbit or mouse immunoglobulin G (IgG) antibodies. They are provided in unlabeled form or as a conjugate with horseradish peroxidase (HRP) enzyme. The antibodies were raised in goat or rabbit using rabbit IgG (H+L) or mouse IgG (H+L), and can be used as a secondary antibody for Western blot (WB) detection, immunohistochemical (IHC) detection, or ELISAs.. ...
These products are affinity-purified IgG antibodies that recognize the heavy and light chains (H+L) of rabbit or mouse immunoglobulin G (IgG) antibodies. They are provided in unlabeled form or as a conjugate with horseradish peroxidase (HRP) enzyme. The antibodies were raised in goat or rabbit using rabbit IgG (H+L) or mouse IgG (H+L), and can be used as a secondary antibody for Western blot (WB) detection, immunohistochemical (IHC) detection, or ELISAs.. ...
Cdc5L Antibody (2136C1a) is a monoclonal anti-Cdc5L antibody that detects m, r, and h Cdc5L by WB, IP, IF and FCM. Cited in 6 publications
CD40 ligand (CD40L) blockade has demonstrated efficacy in experimental autoimmune models. However, clinical trials of hu5c8, an anti-human CD40L IgG1 antibody, in systemic lupus erythematosus (SLE) were halted due to an increased incidence of thrombotic events. This study evaluated CDP7657, a high affinity PEGylated monovalent Fab anti-CD40L antibody fragment, to assess whether an Fc-deficient molecule retains efficacy while avoiding the increased risk of thrombotic events observed with hu5c8. The potency and cross-reactivity of CDP7657 was assessed in in vitro assays employing human and non-human primate leukocytes, and the capacity of different antibody formats to activate platelets in vitro was assessed using aggregometry and dense granule release assays. Given the important role CD40L plays in regulating humoral immunity, in vivo efficacy was assessed by investigating the capacity of Cynomolgus monkeys to generate immune responses to the tetanus toxoid antigen while the potential to induce
Targeting CD40L-CD40 interaction could be useful in clinical applications for curing autoimmune diseases, providing treatment following transplantation and treating tumors [15]. One strategy to disrupt this interaction is to use an anti-CD40L monoclonal antibody: this approach has been shown to be effective in mouse models of RA, SLE, MS, IBD, T1 diabetes, and inflammatory heart disease [29]. The humanized CD40L monoclonal antibody BG9588 (hu5c8) has shown therapeutic effects on SLE patients in clinical trials [17, 30]. Another humanized monoclonal antibody, IDEC-131, was tested in a phase II clinical study in ITP patients [31]. However, they were not approved for clinical use because of thrombotic complications when BG9588 was used in some SLE patients and IDEC-131 was used in treating Crohns disease [27]. A third humanized anti-CD40L antibody, ABI793, targeted a different epitope and was found to have the same thrombotic complications, suggesting that these complications are a common effect ...
APC/Cyanine7 anti-human CD62L Antibody - CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1.
TRANCE/TNFSF11/RANK L Antibody Pair. Matched antibody pairs validated for ELISA or IP-Western Blot. Backed by our 100% Guarantee.
Anti-CD62L antibody conjugated to Biotin [MEL-14] validated for IP, IHC, Flow Cyt, Cytotox, BL and tested in Mouse. Immunogen corresponding to tissue, cells or…
Anti-CD62L antibody conjugated to FITC [MEL-14] validated for IP, IHC, Flow Cyt and tested in Mouse. Referenced in 2 publications. Immunogen corresponding to…
Goat Anti-Guinea Pig IgG (H&L) Antibody (Polyclonal IgG) - Rhodamine Cat#20330101 Details Host:Goat Isotype:IgG Class:Polyclonal Immunogen:Guinea Pig IgG (H&L) Conjugate:Rhodamine Form Information Form:Liquid Concentration:2 mg/mL Purification:Protein A Chromatrography Storage Buffer:PBS with 0.1% BSA Preservative:Upon Request (0.02% Sodium Azide) Storage:Shipped at 4°C. Upon delivery aliquot and store at -20°C in the dark. Avoid freeze / thaw cycles. Usage Recommendations Western Blot (WB):1:3000-1:5000 ELISA:1:150-1:400 Immunoprecipitation (IP):1:350 - 1:500
Research proven purified goat polyclonal FAS Ligand-CD95L Antibody. Excellent marketr for apoptosis. Also used for AD, immune response and cancer research. This antiboy is designed for neutralization of bioactivity, immunohistochemistry, ELISA and western blotting.
BAG1S/1M/1L antibody Rabbit Polyclonal from Proteintech validated in Western Blot (WB), Immunohistochemistry (IHC), Enzyme-linked Immunosorbent Assay (ELISA) applications. This antibody reacts with human, mouse, rat samples. Cat.No. 16150-1-AP. KD/KO Validated.
|strong|Goat anti Pig IgG (H/L) antibody|/strong| recognizes porcine IgG (heavy and light chains) and has been shown to react specifically with porcine IgG and with light chains common to other pig im…
RAD54L antibody LS-C538989 is an FITC-conjugated rabbit polyclonal antibody to RAD54L from human and rodent. Validated for ELISA, ICC and IHC.
THG1L antibody LS-C450503 is an HRP-conjugated rabbit polyclonal antibody to THG1L (aa179-228) from human. It is reactive with human, bat, chimpanzee and other species. Validated for WB.
SeraCare is a trusted partner and worldwide supplier to the diagnostic testing industry, advancing the development of clinical genomics, molecular, and serological diagnostics. Check out how our product, Biotinylated Anti-Bovine IgG (H+L) Antibody 0.5 mg can help with research, development, validation, and lab testing.
Mouse Monoclonal Anti-LUC7L Antibody (2D10) [DyLight 680]. Validated: WB, ELISA, ICC/IF, IP. Tested Reactivity: Human. 100% Guaranteed.
FERD3L antibody, N-term (Fer3-like bHLH transcription factor) for IHC-P, WB. Anti-FERD3L pAb (GTX48965) is tested in Human samples. 100% Ab-Assurance.
MYT1L antibody (myelin transcription factor 1-like) for ICC/IF. Anti-MYT1L pAb (GTX124184) is tested in Human samples. 100% Ab-Assurance.
Gentaur molecular products has all kinds of products like :search , Zyagen \ CSE1L Antibody \ BIN-001434-M08 for more molecular products just contact us
OX40L Monoclonal Antibody, PE conjugate from Invitrogen for Flow Cytometry applications. This antibody reacts with Mouse samples. Clone: OX89. Supplied as 50 ug purified antibody (0.1 mg/ml) in PBS with 4-5mg/ml BSA and 0.02% sodium azide.
Rabbit anti Human Flt3 Ligand antibody recognizes the ubiquitously expressed human growth factor Flt3-Ligand (Flt3L), a 235aa type I trans
Mouse monoclonal antibody raised against a partial recombinant CDC5L. CDC5L (NP_001244, 719 a.a. ~ 802 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. (H00000988-M08) - Products - Abnova
Mouse monoclonal antibody raised against a partial recombinant SKIV2L. SKIV2L (NP_008860, 1125 a.a. ~ 1233 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. (H00006499-M05) - Products - Abnova
Complete information for CCDC71L gene (Protein Coding), Coiled-Coil Domain Containing 71 Like, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium
Complete information for LCA5L gene (Protein Coding), Lebercilin LCA5 Like, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium
Anti-Mouse IgG whole molecule antibody generated in goat detects specifically Mouse IgG whole molecule . This secondary antibody anti-Mouse is ideal for investigators who routinely perform ELISA, Sandwich ELISA, titration assays, western-blot, immunoprecipitation and more generally immunoassays.
Anti-Sheep IgG antibody generated in rabbit detects specifically sheep IgG. This secondary antibody anti-Sheep is ideal for investigators who routinely perform ELISA, Sandwich ELISA, titration assays, western-blot, immunoprecipitation and more generally immunoassays.
Kit Component:- KN308309G1, Immp2l gRNA vector 1 in pCas-Guide vector- KN308309G2, Immp2l gRNA vector 2 in pCas-Guide vector- KN308309D, donor vector…
Kit Component:- KN224821G1, ITIH6 gRNA vector 1 in pCas-Guide vector- KN224821G2, ITIH6 gRNA vector 2 in pCas-Guide vector- KN224821D, donor vector…
This gene encodes a protein that belongs to the pro-apoptotic subfamily within the Bcl-2 family of proteins. The encoded protein binds to Bcl-2 and possesses the BH3 domain. The protein directly targets mitochondria and causes apoptotic changes, including loss of membrane potential and the release of cytochrome c. [provided by RefSeq, Feb 2015] ...
Soluble proteins are poorly immunogenic, and will often lead to Ag-specific tolerance. Similarly, Ag associated with apoptotic cells will frequently induce tolerance. These types of Ag are not very "dangerous", so that recruitment and stimulation of professional APC is minimal. Treatment with the hematopoietic growth factor Fms-like tyrosine kinase 3 ligand (Flt3L) results in tremendous DC expansion, and previous studies have shown that Flt3L treatment can prevent the establishment of tolerance. Yet, the exact mechanism by which Flt3L treatment enhances immune responses remains undefined. I.V. injection of apoptotic cells or soluble Ag into wt mice induces tolerance, but this tolerance is abrogated by treatment with Flt3L. Interestingly, similar abrogation of tolerance was not observed in CD154-/- mice, suggesting a role for CD40-CD40L interaction. Further analysis of Flt3L-treated mice found reduced expansion of CD11c+ cells in CD154-/- mice versus B6 mice. This reduction in CD11c+ cells ...
Direct inhibition of T cell expansion by CD8 T cell CD40L blockade. 2.5 × 106 naive OT-I-RAG−/− cells (Ly5.2) were transferred to Ly5.1 CD40L−/− mice
CD14 (also known lipopolysaccharide [LPS] receptor) is expressed strongly on monocytes and macrophages and weakly on the surface of neutrophils. CD14 (1-201 a.a.) is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentrations as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation. The myeloid differentiation antigen CD14 acts as the major receptor for bacterial LPS. The dominant form of the recombinant wildtype CD14 is the 50 kDa protein.,The rHuCD14 is produced from human CD14-transfected CHO-cells. Before transfection, the complete human CD14-cDNA was amplified by PCR and cloned into expression vector p-POL-DHFR ...
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. ...
DMSO and cellular culture - posted in Tissue and Cell Culture: Hello I have the following problem: I have to use a compound that dissolves only in DMSO 100%. I need to use it in cellular cultures of certain endothelial cells and stellate cells, that are exquisivitely sensitive to DMSO. At 0.01% DMSO, those cells die. I need to use the compound at 1 to 10 micromol/l concentrations, and I am not able to make a stock solution above 10 mmol/l, or this compound does not dissolve even in DMSO....
CD154 (CD40 Ligand), PE, clone: MR1, eBioscience™ 50μg; PE CD154 (CD40 Ligand), PE, clone: MR1, eBioscience™ Primary Antibodies CD151 to CD200
CD154 (CD40 Ligand), FITC, clone: 24-31, eBioscience™ 100 Tests; FITC CD154 (CD40 Ligand), FITC, clone: 24-31, eBioscience™ Primary Antibodies CD151 to CD200
Dybul M, Mercier G, Belson M, Hallahan C, Liu S, Perry C, Herpin B, Ehler L, Davey R, Metcalf J, Mican J, Seder R, Fauci AS. CD40 ligand trimer and IL-12 enhance PBMC and CD4+ T-cell proliferation and production of IFN-γ in response to p24 antigen in HIV-infected individuals: potential contribution of anergy in the lack of HIV-specific unresponsiveness. J Immunol. 2000;165:1685-1692 ...
CD154 (CD40 Ligand), Functional Grade, clone: MR1, eBioscience™ 50μg; Functional Grade CD154 (CD40 Ligand), Functional Grade, clone: MR1, eBioscience™...
Serem free T4 level is 11.7 pmo/L (range 9.0 - 19.1) Serem TSH level is 1.9 mU/L (range 0.35 - 4.94) Vitamin D is borderline - Combined D2 & D3 level is 62 nmo/L levels should be | 75nmo/L - levels...
We describe the construction of a novel soluble dodecameric form of CD154 (CD40 ligand) that is more effective than trimeric tCD154 in triggering B cell activation. Dodecameric surfactant protein (SP)-D-CD154 was more potent than tCD154 in inducing B cell proliferation over a wide range of concentra …
T Precious Waters,QID,28730,M,41.72,63.58;47.36,55.68,CS,N,Up the ramp to Tenaron Stormgrip.,R,Night Elf,. L Level 5,QID,28730,LVL,5,N,You should be around level 5 by this point.,. A Teldrassil: Passing Awareness,QID,28731,PRE,28730,M,47.36,55.68,N,From Tenaron Stormgrip.,R,Night Elf,. r Aldrassil,QID,28731,NC,M,48.73,61.55,N,Repair and Restock. Sell junk and train.,R,Night Elf,. A Dolanaar Delivery,QID,2159,M,54.65,84.44,N,From Porthannius.,. ]]. end). ...
specificalPrinciple of the Assay: CD40L ELISA kit applies the competitive enzyme immunoassay technique utilizing a monoclonal anti-CD40L antibody and an CD40L-HRP conjugate. The assay sample and buffer are incubated together with CD40L-HRP conjugate in pre-coated plate for one hour. After the incubation period, the wells are decanted and washed five times. The wells are then incubated with a substrate for HRP enzyme. The product of the enzyme-substrate reaction forms a blue colored complex. Finally, a stop solution is added to stop the reaction, which will then turn the solution yellow. The intensity of color is measured spectrophotometrically at 450nm in a microplate reader. The intensity of the color is inversely proportional to the CD40L concentration since CD40L from samples and CD40L-HRP conjugate compete for the anti-CD40L antibody binding site. Since the number of sites is limited, as more sites are occupied by CD40L from the sample, fewer sites are left to bind CD40L-HRP conjugate. A ...
Purified Recombinant Human CD96 protein, Mouse IgG2a Fc-tagged, low endotoxin from Creative Biomart. Recombinant Human CD96 protein, Mouse IgG2a Fc-tagged, low endotoxin can be used for research.
Purified Recombinant Human CD47 protein, Fc/Avi-tagged, Biotinylated from Creative Biomart. Recombinant Human CD47 protein, Fc/Avi-tagged, Biotinylated can be used for research.
Recombinant Human CD96 Protein (His Tag) product information; Recombinant Human CD96 Protein (His Tag) is available 1 time from supplier adv at Gentaur.com shop
Results Histological analysis of paws showed increased synovial infiltration and joint destruction in WT mice while Flt3L-/- mice showed mild infiltration without inflammation (H&E staining). Cartilage destruction (Safranin O staining) and the number of osteoclast were higher in WT compared with Flt3L-/- mice. Importantly, in steady-state (no CIA induced), Flt3L-/- mice show reduced celularity in both spleen (p=0.007) and LN (p=0.01) and reduced T and B cell numbers compared with WT. CIA induction in Flt3L-/- led to decreased disease incidence and severity (AUC p=0.001) compared with WT littermates. In addition, Flt3L-/- mice showed reduced spleen and LN cellularity (p,0.0001) but also reduced percentage of CD4+CD25+T cells compared with WT (p=0.03). Flt3L-/- CD4+ T cells produced significantly less IL-17 (p=0.016) and TNF-a (p=0.010) while CD8+ T cells produced less IFN-g (p=0.029) compared with WT.. ...
Jakarta, Indonesia - September 3, 2020 Merck KGaA, Darmstadt, Germany Supports Eijkman Institute to Expedite Covid-19 Vaccine Development Research Merck KGaA, Darmstadt, Germany today announced the donation of research instruments and materials worth IDR 1.2 billion (€ 74,000) to support the efforts of Eijkman Institute for Molecular Biology, Indonesia, in its efforts to accelerate vaccine development research. The institute is developing a Covid-19 vaccine based on a local virus strain, in collaboration with several local research institutions.. Read More ...