Common carotid artery stenosis is often diagnosed when actually looking for internal carotid artery stenosis. The methods for diagnosis include duplex ultrasound and computed tomography. The criteria for the diagnosis of common carotid artery stenosis are unclear. The convention is that a doubling of the flow velocity between adjacent artery segments denotes significant stenosis. A retrospective analysis compared duplex ultrasound of 62 patients with common carotid artery stenosis to CT. A peak systolic velocity >182 cm/sec and an end-diastolic velocity >30 cm/sec were the most accurate as assessed by receiver-operating curves. While sensitivity was not very high, specificity was better. In this analysis duplex ultrasonography was also accurate in detection of common carotid artery occlusion, albeit in a small number of patients.. ...
In anatomy, the left and right common carotid arteries (carotids) (English: /kəˈrɒtɪd/) are arteries that supply the head and neck with oxygenated blood; they divide in the neck to form the external and internal carotid arteries. The common carotid arteries are present on the left and right sides of the body. These arteries originate from different arteries, but follow symmetrical courses. The right common carotid originates in the neck from the brachiocephalic trunk; the left from the aortic arch in the thorax. These split into the external and internal carotid arteries at the upper border of the thyroid cartilage, at around the level of the fourth cervical vertebra. The left common carotid artery can be thought of as having two parts: a thoracic (chest) part and a cervical (neck) part. The right common carotid originates in or close to the neck, so contains only a small thoracic portion. There are studies in the bioengineering literature that have looked into characterizing the geometric ...
In this large-scale study of subjects 65 to 85 years of age, we found an association between CCA-IMT or carotid plaques and 2 measures of motor function. The association was attenuated after adjustment for vascular risk factors, thus suggesting that CCA-IMT or carotid plaques are intermediate variables.. The most likely explanation for this association is that individuals with higher CCA-IMT values are at increased risk of cerebral white matter hyperintensities (WMHs) and silent infarcts.16-18 Previous studies have shown that WMHs are more common in subjects performing worse on several measures of gait and balance; for instance, in the Cardiovascular Health Study, several measures of motor function were associated with WMHs in subjects ≥65 years of age.17 This finding was confirmed in smaller cross-sectional19 and longitudinal studies.20,21 Alternatives mechanisms (eg, peripheral diabetic neuropathy) are less likely because adjustment for diabetes or exclusion of diabetic subjects did not ...
The left common carotid artery is the artery that provides oxygen-rich blood to the left side of the neck and the head. Within the neck, the left common carotid artery extends out into the left external carotid artery and the left internal carotid artery.. ...
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0002] At the present time, physicians often treat carotid artery obstructive disease with the placement of a stent. This stent is typically placed in the internal carotid artery, in the common carotid artery, or spanning both arteries with the distal portion of the stent in the internal carotid artery and the proximal portion of the stent in the distal common carotid artery. The start of this procedure necessitates the placement of either a long sheath or a guiding catheter into the common carotid artery proximal to the carotid stenosis to be treated. The placement of such a sheath or guiding catheter can often be extremely challenging due to the tortuous course for access from the aortic arch into the common carotid artery. This is particularly an issue when accessing the right common carotid artery, which typically arises as a proximal branch from the inominate artery. Many different "tricks" are used to try to place relatively stiff sheaths and guiding catheters into the carotid circulation. ...
Lapi, D.; Marchiafava, P.L.; Colantuoni, A., 2007: Pial microvascular responses to transient bilateral common carotid artery occlusion: effects of hypertonic glycerol
Approach and Results-We tested whether M1 macrophages produce galectin-3-binding protein in vitro. Then, we measured galectin-3-binding protein and the soluble macrophage biomarkers soluble cluster of differentiation 163 and soluble cluster of differentiation 14 in 264 participants in the Womens Interagency HIV Study. Women were positive for HIV, HCV, both, or neither (66 in each group, matched for age, race/ethnicity, and smoking status). Carotid artery disease was assessed by ultrasound measurement of right distal common carotid artery intima-media thickness, distensibility, and presence of atherosclerotic lesions (IMT,1.5 mm). Plasma galectin-3-binding protein was higher in HCV+ than HCV− women (P,0.01) but did not differ by HIV status. The 3 inflammatory macrophage markers were significantly correlated with each other and negatively correlated with cluster of differentiation (CD)4+ counts in HIV-infected women. We defined a macrophage score as 1, 2, or 3 biomarkers elevated above the ...
The aim of this study is to conduct in vivo, noninvasive magnetic resonance imaging of labeled rat bone mesenchymal stem cells (BMSCs) as they home into the site of injured common carotid artery following allograft transplantation. Our study was approved by the Institutional Committee on Animal Research. Purified rat BMSCs were dual labeled with superparamagnetic iron oxide (SPIO) particle and fluorescent DiI dye, and subsequently transplanted into recipient rats injured in the left common carotid arteries. Immediately before and 3 hr, 3, 7 and 12 days after transplantation, the labeled cells were monitored in vivo using a 7T micromagnetic resonance imaging (7T micro-MRI) scanner. The signal-to-noise ratios (SNRs) at the injured sites were corroborated with histological examination using Prussian blue staining and fluorescent imaging. Rat BMSCs were labeled with SPIO and DiI at 100% efficiency. When compared with the baseline level before transplantation, the SNR decreased significantly on Days ...
The common carotid artery is found bilaterally, with one on each side of the anterior neck. Each common carotid artery is divided into an external and internal carotid artery. These arteries transfer blood to the structures inside and outside of the skull.
Common carotid artery intima-media thickness (CIMT), as measured by ultrasound, has utility in stratification of the accelerated cardiovascular risk seen in rheumatoid arthritis (RA); however, the technique has limitations. Carotid magnetic resonance imaging (MRI) is emerging as a useful research tool in the general population, but has yet to be applied in RA populations. Our objectives were to describe the utility of carotid artery MRI (carotid-MRI) in patients with RA in comparison to healthy controls and to describe the association with RA disease phenotype. Sixty-four patients with RA and no history of cardiovascular (CV) disease/diabetes mellitus were assessed for RA and CV profile, including homeostasis model assessment-estimated insulin resistance (HOMA-IR) and N-terminal pro-brain natriuretic peptide (NT-proBNP). All underwent carotid-MRI (3 T), and were compared to 24 healthy controls. Univariable analysis (UVA) and multivariable linear regression models (MVA) were used to determine
BACKGROUND AND AIMS: Common mechanisms for the development of micro- and macroangiopathic diabetic complications have been suggested. We aimed to cross-sectionally investigate strength and characteristics of the association between carotid atherosclerosis and microangiopathy in type 2 diabetic patients. METHODS AND RESULTS: Common carotid artery intima-media thickness (cIMT), carotid plaque (CP) type and degree of stenosis were evaluated by ultrasound, along with the determination of anthropometric parameters, HbA1c, lipid profile, assessment of diabetic retinopathy and nephropathy, in 662 consecutive patients with type 2 diabetes mellitus (T2DM). Patients were divided according to high/low cIMT, presence/absence of CP and of retinopathy and nephropathy. Patients with CP were older, more prevalently males, past smokers, had longer diabetes duration, significantly lower HDL cholesterol and more prevalent ischemic heart disease (all p,0.05) as compared to those with cIMT , 1 mm. Microangiopathies ...
Aims: To investigate the association between intima-media thickness of brachial and common carotid arteries and factors of the coagulation- and fibrinolysis system with diastolic dysfunction in patients with a previous myocardial infarction. Patients and methods: One hundred and five patients, men (72 %) and women (28%) aged between 32-73 years with a history of previous acute myocardial infarction were included. An age-matched control group with no cardiovascular risk factors was used as a comparison. B-mode ultrasound of common carotid and brachial arteries and echocardiography were evaluated in all subjects. Calculated intima-media area (cIMa) of the common carotid and brachial arteries and tissue Doppler imaging (TDI) were examined. Factors of the coagulation- and fibrinolysis system were also measured. Results: Prothrombin fragment 1+2 was significantly higher in patients with previous myocardial infarction compared to the control group ( ...
TY - JOUR. T1 - Common carotid arterial stiffness and the risk of ischaemic stroke. AU - Tsivgoulis, Georgios. AU - Vemmos, K.. AU - Papamichael, C.. AU - Spengos, K.. AU - Daffertshofer, M.. AU - Cimboneriu, A.. AU - Zis, V.. AU - Lekakis, J.. AU - Zakopoulos, N.. AU - Mavrikakis, M.. PY - 2006/5/1. Y1 - 2006/5/1. N2 - In the present case-control study we aimed to investigate the association of common carotid arterial (CCA) stiffness with ischaemic stroke (IS) and to determine whether this relationship was independent of conventional risk factors including CCA intima-media thickness (CCA-IMT). CCA distensibility, defined as the change of CCA-diameter during the cardiac cycle, and CCA-IMT were evaluated by means of high-resolution B-mode carotid ultrasound examination in consecutive, first-ever IS patients (n = 193) and in age- and sex-matched control subjects (n = 106). The CCA distensibility (inverse of CCA stiffness) was significantly (P = 0.007) lower in IS (0.353 mm, 95% CI: 0.326-0.379) ...
Stroke is ranked as the number one cause of death in Vietnam and the second leading cause of death in the world. Stenosis in the carotid arteries is one of the major risk factors for stroke, making it extremely important to confirm the diagnosis. Duplex ultrasound including measurements of the peak systolic velocity is considered the most accurate method when it comes to screening of carotid stenosis. However, the survey method is user dependent and differences in the results related to the scanning technique of the examiner may occur. The aim of this study was to determine the diagnostic variability for measuring peak systolic velocity in the common carotid artery in order to investigate whether the obtained results differ depending on the examiner. 30 healthy volunteers underwent carotid duplex ultrasound performed by two different examiners. Peak systolic velocity was measured with pulsed waved Doppler caudally of the carotid bifurcation. A T-test and a Bland-Altman plot were later applied in ...
Among older men with low or low-normal testosterone levels, testosterone administration for 3 years vs placebo did not result in a significant difference in the rates of change in either common carotid artery intima-media thickness or coronary artery calcium. Read all about it in JAMA. 2015;314(6):570-581
Noninvasively determined local wave speed ( c) and wave intensity (WI) parameters provide insights into arterial stiffness and cardiac-vascular interactions in response to physiological perturbations. However, the effects of incremental exercise and subsequent recovery on c and WI have not been fully established. We examined the changes in c and WI parameters in the common carotid artery (CCA) during exercise and recovery in eight young, healthy male athletes. Ultrasound measurements of CCA diameter and blood flow velocity were acquired at rest, during five stages of incremental exercise (up to 70% maximum work rate), and throughout 1 h of recovery, and noninvasive WI analysis [diameter-velocity ( DU) approach] was performed. During exercise, c increased (+136%), showing increased stiffness with work rate. All peak and area of forward compression, backward compression, and forward expansion waves increased during exercise (+452%, +700%, and +900%, respectively). However, WI reflection indexes ...
TY - JOUR. T1 - Effect of increased severity in patient specific stenosis of common carotid artery using CFD-a case study. AU - Khader, S. M.Abdul. AU - Shenoy, B. Satish. AU - Pai, Raghuvir. AU - Kamath, S. Ganesh. AU - Sharif, Nabeel Md. AU - Rao, V. R.K.. PY - 2011. Y1 - 2011. N2 - The prevailing vascular fluid dynamics plays an important role in the development of atherosclerosis which is one of the most wide spread disease in humans. The recent advances in computational fluid dynamics (CFD) can be useful in observing the flow behavior downstream of the stenosis. The present study investigates a simple case of 66% eccentric stenosis of an approximate model generated from Doppler scan. The blood is assumed to be incompressible, homogenous and Newtonian, while artery is assumed to be a rigid wall. The transient analysis is performed using ANSYS-10.0, commercially available Finite Element Software. The flow pattern, Wall Shear Stress (WSS) and pressure contours are observed at pre-stenotic, ...
The right common carotid artery arises from the brachiocephalic. The left common carotid usually arises as the second arch vessel. The common carotids normally have no branches. The first branch of the subclavian artery on each side are the vertebral arteries, which ascend posterior to the carotids. Notes ...
A key artery located in the front of the neck though which blood from the heart goes to the brain. There are 2 carotid arteries the right and left common carotid arteries on each side of the neck. Together, the right and left common carotid…
... Artery: Common carotid artery Schematic of the proximal aorta and its branches. Arteries of the neck. The internal carotid arteries arise
The selective a2 -adrenoceptor agonist UK-14304 produces a small vasoconstrictor response in the rat isolated carotid artery. The purpose of the work presented here was to investigate whether stimuli that produce submaximal contraction would potentiate responses to UK-14304. Male Wistar rats were killed by overdose with pentobarbitone sodium, after which the ...
MUNIZ, Luiz Roberto Franklin; FARIA, Mário Henrique Girão and VASCONCELOS, Paulo Roberto Leitão de. Metabolic evaluation of ischemic and reperfusion brain injury following bilateral occlusion of common carotid arteries: an experimental study in rats. Acta Cir. Bras. [online]. 2004, vol.19, n.5, pp.529-534. ISSN 0102-8650. http://dx.doi.org/10.1590/S0102-86502004000500012.. PURPOSE: To describe alterations on the energy metabolism after cerebral ischemia/reperfusion, through an experimental model of reversible global ischemia, by simple occlusion of common carotid arteries (CCAs) in rats of Wistar lineage. METHODS: Forty-eight male Wistar rats were randomly distributed on two groups (C - Control; T - Test) and further redistributed into four times sets of study. After bilateral occlusion of CCAs for 30min, the animals of group T were allowed reperfusion for 0, 5, 10 and 15min. Samples of cerebral tissue and systemic arterial blood were collected and the metabolites D-glucose (GLI), pyruvate ...
Extracranial Cerebrovascular Evaluation. Anatomy. Carotid Artery Anatomy. Branches of the Aortic Arch Innominate Left CCA Left Subclavian Innominate branches into Right CCA Right Subclavian. Rt. Common Carotid A. Rt. Subclavian A. Lt. Common Carotid A. Lt. Subclavian A. Innominate A. Slideshow 1328109 by maurice
DataMed is a prototype biomedical data search engine. Its goal is to discover data sets across data repositories or data aggregators. In the future it will allow searching outside these boundaries. DataMed supports the NIH-endorsed FAIR principles of Findability, Accessibility, Interoperability and Reusability of datasets with current functionality assisting in finding datasets and providing access information about them.
Coregistered 3D rendered ultrasound (greyscale) and color Doppler (red and blue) coronal image of a mouse brain during ligation of the right common carotid artery.&nbs
Ultrasound. An integrated modular neural network multi-feature/multi-classifier diagnostic system, including image normalization, despeckle filtering, plaque segmentation, texture and morphological feature extraction, and neural network classification has been developed for differentiating between asymptomatic and symptomatic plaques in ultrasound imaging of the carotid for the assessment of the risk of stroke. This is the only carotid plaque diagnostic system that covers all image processing steps from acquisition to diagnosis. The image normalization and texture feature extraction modules of this system are used in several cardiovascular clinics in North America, Europe, and Asia, including Columbia University, McGill University, Imperial College, Tromso University, and others. Moreover, an automated system for segmenting and computing the texture of the intima and media layer thickness of the common carotid artery as prognostic indicators for atherosclerosis versus the intima media thickness ...
Vascular surgeons are used to treating symptomatic atherosclerotic lesions at the carotid bifurcation, sometimes at the origin of the common carotid artery (cca), and even tandem lesions. in contrast, thromboembolic occlusion of the supra-aortic vessels is very rare E. Chisci ...
Atherosclerotic cardiovascular disease is the leading cause of death worldwide. To decrease mortality and morbidity in cardiovascular disease, the development of accurate, non-invasive methods for early diagnosis of atherosclerotic cardiac and vascular engagement is of considerable clinical interest. Cardiovascular ultrasound imaging is today the cornerstone in the routine evaluation of cardiovascular function and recent development has resulted in two new techniques, tissue velocity imaging (TVI) and speckle tracking, which allow objective quantification of cardiovascular function. TVI and speckle tracking are the basis for three new approaches to cardiac and vascular monitoring presented in this thesis: wave intensity wall analysis (WIWA), two-dimensional strain imaging in the common carotid artery, and the state diagram of the heart.. WIWA uses longitudinal and radial strain rate as input for calculations of wave intensity in the arterial wall. In this thesis, WIWA was validated against a ...
OZCETIN, Mustafa et al. The importance of carotid artery stiffness and increased intima-media thickness in obese children. SAMJ, S. Afr. med. j. [online]. 2012, vol.102, n.5, pp.295-299. ISSN 2078-5135.. BACKGROUND: Atherosclerosis that starts in childhood invariably advances during adulthood. AIM: We aimed to study the effect of obesity on main carotid artery intima-media thickness (CIMT) and arterial stiffness. MATERIAL AND METHODS: A total of 78 children were studied from October 2010 to February 2011. They were divided into obese (n=42, group 1) and normal (n=36, group 2). All children were subjected to physical examination, routine biochemical and haematological analysis, carotid ultrasonography and echocardiographic measurements. A detailed medical history was obtained. Body mass index (BMI) was calculated by dividing participants weight in kilograms by the square of their height in metres. Stiffness index β was calculated using blood pressure and diameter of the systolic and diastolic ...
BACKGROUND: A phenomenon of endothelial impairment, independent of classical cardiovascular risk factors, has been observed in young people. We identified subjects with persistently reduced, or declining, endothelial function during adolescence and early adulthood, without apparent cardiovascular risk, and investigated the clinical relevance of this finding. METHODS: Endothelial vasomotor responses were assessed by brachial artery flow-mediated dilatation (FMD) at age 15 years in 47 subjects (22 males) who returned for a repeated measurement at age 25. Subjects underwent quantification of left ventricular mass (LVM) and function by cardiovascular magnetic resonance, central arterial stiffness by applanation tonometry, and common carotid artery intima-media thickness using ultrasound on their visit at age 25. RESULTS: Individuals with low average FMD over 10-year period, although normotensive, had 5 mm Hg higher systolic blood pressure and, significantly greater LVM (73.48 ± 7.73 vs. 56.25 ± 9.54 g/m(2
OBJECTIVE: The purpose of this study was to examine the association between adiposity measures, ultrasound image quality, and preclinical markers of atherosclerosis in young adults. METHODS: B-mode ultrasound was used to obtain common carotid intima-media thickness and common carotid artery distensibility of 2265 and 1313 adults aged 24 to 39 years in two population-based studies: the Cardiovascular Risk in Young Finns and Childhood Determinants of Adult Health studies. Qualitative assessments of ultrasound image quality were obtained from each study (scored as 1, excellent; 2, average; and 3, poor) based on the ability to detect arterial interfaces and the amount of noise present in the image. RESULTS: Increased adiposity was associated with significantly increased odds (all P | .05) of average or poor carotid ultrasound image quality. Reduced image quality was associated with lower intima-media thickness in Young Finns (regression coefficient = -0.029; P = .01) and higher intima-media thickness in
BACKGROUND: Partial GH deficiency (GHD) in adults is poorly studied. OBJECTIVE: The objective of the study was to investigate the natural history and clinical implications of partial GHD. STUDY DESIGN: This was an analytical, observational, prospective, case-control study. PATIENTS: Twenty-seven hypopituitary patients (15 women, ages 20-60 yr) and 27 controls participated in the study. MAIN OUTCOME MEASURES: Measures included GH peak after GHRH plus arginine [(GHRH+ARG), measured by immunoradiometric assay]; IGF-I (measured after ethanol extraction) z-sd score (SDS); glucose, insulin, total cholesterol, high-density lipoprotein (HDL) cholesterol, and triglyceride levels; and common carotid arteries intima-media thickness (IMT) measured periodically. RESULTS: At study entry, partial GHD patients had significantly lower IGF-I and HDL-cholesterol levels and homeostasis model assessment index than controls. During the 60 months of median follow-up, 11 patients had severe GHD (40.7%), seven ...
Carotid artery - What are the carotid arteries? Carotic Arteries. The human carotid arteries supply the head and the neck with oxygenated blood. The left common carotid artery originates from the aorta and the right common carotid originates from the brachiocephalic artery which originates from the aorta. The carotic artery divides in the neck to form the internal and external carotic arteries.
Four vessels arise sequentially from the aortic arch: the right common carotid artery, the left common carotid artery, the left subclavian artery and the aberrant right subclavian artery, which crosses upwards and to the right in the posterior mediastinum. It results from a disruption in the complex remodelling of the paired branchial arches, typically of the right dorsal aorta distal to the sixth cervical intersegmental artery. [1, 2 ...
Colbert, S.A., et al. (1998) The Laryngeal Mask Airway Reduces Flow in the Common Carotid Artery Bulb. Canadian Journal of Anesthesia, 45, 23-27.
Increased arterial stiffness assessed by increase PWV and increased pulse pressure have been shown to relate directly with cardiovascular events.23,24 Similar prognostic information can be gained from BRS evaluation in different patient populations at risk for cardiovascular complications. Previous investigations have demonstrated that BRS is significantly related to carotid artery distensibility. A positive association between the elastic properties of the carotid artery and BRS has been reported in healthy volunteers,25 pregnant women,26 hypertensive subjects,27 and nondiabetic patients with carotid artery stenosis.28 However, in this study we did not observe any correlation between BRS and common carotid artery wall distensibility in T2DM patients with at least 2 additional cardiovascular risk factors.. This T2DM population differs significantly from previously published works. We have selected high-risk subjects with T2DM who are characterized by stiffened and diseased arteries as evidenced ...
BACKGROUND:. A finding from the Cholesterol Lowering Atherosclerosis Study (CLAS), a clinical trial, indicated that common carotid intima-media thickness responded more rapidly and more markedly to LDL-C lowering treatment than angiographic coronary stenosis or carotid roughness. New data from a primate model also showed ultrasound detection of intimal thickening in response to a hypercholesterolemic diet within twelve months. These findings suggest that carotid IMT is a reliable and rapidly responding marker of extent of atherosclerosis. However, less than a third of the observed therapeutic benefit on carotid IMT found in CLAS was explained by change in LDL-C and HDL-C, suggesting that related (or other) factors are more directly linked to atherogenic mechanisms. In addition, a Finnish epidemiologic study found that LDL-C was predicative of rate of progression in carotid IMT only in persons with high serum levels of (pro-oxidant) copper. . These and other data support a model of ...
Dietary supplementation with polyphenolic antioxidants to animals was shown to be associated with inhibition of LDL oxidation and macrophage foam cell formation, and attenuation of atherosclerosis development. We investigated the effects of pomegranate juice (PJ, which contains potent tannins and anthocyanins) consumption by atherosclerotic patients with carotid artery stenosis (CAS) on the progression of carotid lesions and changes in oxidative stress and blood pressure. Ten patients were supplemented with PJ for 1 year and five of them continued for up to 3 years. Blood samples were collected before treatment and during PJ consumption. In the control group that did not consume PJ, common carotid intima-media thickness (IMT) increased by 9% during 1 year, whereas, PJ consumption resulted in a significant IMT reduction, by up to 30%, after 1 year. The patients serum paraoxonase 1 (PON 1) activity was increased by 83%, whereas serum LDL basal oxidative state and LDL susceptibility to copper ...
Background: Neurologic damage following ischemic insult is a major problem for stroke survivors. Xenon (Xe) exerts favorable neuroprotective properties with few side effects. This study describes a unique application of ultrasound for controlled release of Xe from liposomes (Xe-ELIP) for targeted therapeutic gas delivery and neuroprotection.. Method: Xe-ELIP were created by a pressurization-freezing method. One-MHz continuous ultrasound wave with pressure amplitudes of 0.16, 0.22 and 0.33 MPa was used to trigger Xe release from Xe-ELIP, and endothelial cell permeability and cell viability were measured. Male Sprague-Dawley rats underwent right middle cerebral artery occlusion for 2 hours (n=28). In the treatment group (n=8), Xe-ELIP were administered through the right common carotid artery. Continuous ultrasound (0.22 MPa) was applied over the common carotid artery during the Xe-ELIP administration for 4 minutes. Infarct size as well as behavioral outcomes were determined 3 days after ...
TY - JOUR. T1 - Two stage successive carotid artery occlusion surgeries in wistar rat reduce its mortality and depicts as a better model for vascular dementia. AU - Siva Kumar, G.. AU - Vidyadhar, D. J.. AU - Punja, Dhiren. AU - Rajesh, T.. AU - Reddy, Ashok P.M.. AU - Huban Thomas, R.. AU - Ramesh Babu, M. G.. PY - 2015/1/1. Y1 - 2015/1/1. N2 - Chronic cerebral hypoperfusion induced vascular dementia (VD) constitutes a major cause for dementia in the geriatric population. Permanent-bilateral common carotid artery occlusion (P-BCCAO) in Wistar rat models are considered as accepted models for preclinical research on VD. It has been documented that the P-BCCAO rats undergo a brief period of acute severe ischemia immediately following P-BCCAO surgery. This offers a significant disadvantage in using this model to study chronic cerebral hypoperfusion induced VD in human beings. Moreover, the survival rate of this rat model is relatively low compared to other animal models being used for similar ...
TY - JOUR. T1 - Purposeful delay in the repair of a traumatic left common carotid pseudoaneurysm in a bovine aortic arch presenting as a widened mediastinum. AU - Hendrickson, Richard J.. AU - Koniaris, Leonidas. AU - Jiang, Shao. AU - Waldman, David. AU - Massey, H. Todd. AU - Sitzmann, James V.. PY - 2002/12/1. Y1 - 2002/12/1. UR - http://www.scopus.com/inward/record.url?scp=0036900943&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0036900943&partnerID=8YFLogxK. M3 - Article. C2 - 12478045. AN - SCOPUS:0036900943. VL - 53. SP - 1166. EP - 1169. JO - Journal of Trauma and Acute Care Surgery. JF - Journal of Trauma and Acute Care Surgery. SN - 2163-0755. IS - 6. ER - ...
Video articles in JoVE about neck muscles include In Vivo Gene Transfer to the Rabbit Common Carotid Artery Endothelium, Neck Exam, Utilizing Transcranial Magnetic Stimulation to Study the Human Neuromuscular System, A Model of Free Tissue Transfer: The Rat Epigastric Free Flap, In Vivo Evaluation of the Mechanical and Viscoelastic Properties of the Rat Tongue, Coordinate Mapping of Hyolaryngeal Mechanics in Swallowing, Non-invasive Assessment of Changes in Corticomotoneuronal Transmission in Humans, Subcutaneous Neurotrophin 4 Infusion Using Osmotic Pumps or Direct Muscular Injection Enhances Aging Rat Laryngeal Muscles, Method to Measure Tone of Axial and Proximal Muscle, Repeated Measurement of Respiratory Muscle Activity and Ventilation in Mouse Models of Neuromuscular Disease, Diagnostic Necropsy and Tissue Harvest, Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models, The Mesenteric Lymph Duct Cannulated Rat
misc{3051799, abstract = {Cardiovascular diseases, such as atherosclerosis, is a major cause of mortality in, primarily, the western world. To be able to recognize early symptoms of this type of diseases it has proven to be important to investigate the mechanical properties of blood vessels. A few years back from now it became evident that the common carotid artery has a distinct bidirectional movement pattern in the longitudinal direction during each cardiac cycle. The mechanisms of this behavior has however since then been undetermined. In this study three independent indicators of the cardiac wall movements involvement is presented. By ultrasound examinations of both the right and left side common carotids and simultaneous examinations of left ventricle movement of the heart of 14 humans it has become evident that: The longitudinal movement in the carotid arterial wall, in both directions, occurs in parts of the vessel close to the heart before it is transmitted to more peripheral parts of ...
Objective: People living with HIV (PLWH) have chronic immune activation and increased cardiovascular disease (CVD) risk. Activation of monocytes and T lymphocytes causes upregulation of glucose transporter-1 (GLUT1) for efficient function. PLWH have an increased percentage of GLUT1-expressing monocytes and T lymphocytes, but it is unclear if these cells are associated with CVD. We evaluated the expression of GLUT1 and CD38 on monocyte and T lymphocyte populations from HIVinfected women with subclinical CVD. Methods: Participants with more than 75th percentile (n-15) and less than 25th percentile (n=15) age-Adjusted intima-media thickness (IMT) at the right common carotid artery and bifurcation were identified from the Womens Interagency HIV Study. Groups were matched by age, race/ethnicity, smoking status, and CD4 cell count. All women were receiving suppressive antiretroviral therapy except for one high and one low IMT participant. Monocyte and T lymphocyte populations were evaluated for GLUT1 ...
Table 23-4 vaccination of patient, family, and other health needs stiffness joint prednisone. Reliability and validity confirmed 2018). Junctional escape beats if they develop. 5. Rectal infection, pharyngitis, conjunctivitis, skin lesions, dry skin, thin hair and wear a medicalert bracelet or necklace, and inform caregivers that autonomic dysreflexia occurs: Check bp; if elevated, via an ommaya reservoir or by gently rolling the ngers for edema around the distal common carotid artery. Family education and health policy curley, m. , gornik, h. L. , et al. Involving the middle of fvc and/or diffusion capacity of the, table 21-1 signs and symptoms that occur with hsv4 because of decrease in absorption or intake; cobalamin is the single photons emitted from device are not suitable for osteotomies or reconstruction of the bowel. Multiple pheresis, or removal of the access vessels are encountered, coming from the toes pointed toward the right-hand side has shown that atherosclerosis regression in ...
Hypoxia-ischemia in 7-d-old rats. The Rice-Vannucci (Rice et al., 1981) neonatal adaptation of the Levine procedure (Levine, 1960) was used to cause hypoxic-ischemic brain injury in 7-d-old (p7) rats. In brief, rat pups were anesthetized with 2.5% halothane and 15% nitrous oxide in O2. The right common carotid artery was permanently ligated (in sham controls the ligature was passed around the artery and removed). After the wound was sutured, the pups recovered from anesthesia and were returned to the dam. Two hours later, pups were placed in an airtight container in a 37°C water bath through which humidified 8% O2and balance nitrogen flowed for 150 min. After hypoxia, pups were returned to the dam until death.. The animals were killed, and the brains were retrieved at 0, 1.5, 3, 6, and 24 hr after the end of hypoxia for histological analysis (n = 6 for each time point) or at 3, 6, and 24 hr after the end of hypoxia for Western blotting. Because of the small size of the immature rat thalamus, ...
THURSDAY, Oct. 11, 2018 (HealthDay News) - Common carotid artery (CCA) wall thickness measured using magnetic resonance imaging (MRI) is more consistently associated with incident cardiovascular disease (CVD) outcomes than intima-media thickness measured by ultrasound, according to a study published online Oct. 9 in Radiology.. Yiyi Zhang, Ph.D., from the Johns Hopkins University Bloomberg School of Public Health in Baltimore, and colleagues conducted a prospective study involving 698 participants without a history of clinical cardiovascular disease from the Multi-Ethnic Study of Atherosclerosis. CCA wall thickness was measured with ultrasound and with non-contrast proton density-weighted and intravenous gadolinium-enhanced MRI. The correlations between wall thickness measured with ultrasound and MRI were assessed with CVD outcomes.. The researchers found that per standard deviation increase in intima-media thickness, the adjusted hazard ratios for coronary heart disease, stroke, and CVD were ...
The carotid artery is one of the major arteries of the human body. It helps blood flow to and from a humans heart. In human anatomy, the left and right common carotid arterie are arteries that supply the head and neck with oxygenated blood.. ...
Introduction: Elevated levels of G protein-coupled receptor kinase 2 (GRK2) are associated with human hypertension and animal models of the disease. GRK2 is also increased in heart failure (HF). GRK2ct, a peptide inhibitor of GRK2 (last 194 amino acids of GRK2) is effective at rescuing models of HF through its restoration of cardiac βAR signaling.. Hypothesis: Our interest is in investigating the role of VSM GRK2ct to determine if it is an effective antihypertensive strategy.. Methods: We created transgenic mice that express the GRK2ct peptide in VSM using a portion of the SM22 promoter (VSM-GRK2ct). Conscious BP was derived using a fluid-filled indwelling left common carotid artery catheter. In vivo BP response to acute agonist infusion administered via the jugular vein was recorded in anesthetized mice. Vascular reactivity was determined by force displacement in aortic rings after mechanical endothelial cell denudation.. Results: RNA and protein levels verified VSM-specific expression in 2 ...