OZCETIN, Mustafa et al. The importance of carotid artery stiffness and increased intima-media thickness in obese children. SAMJ, S. Afr. med. j. [online]. 2012, vol.102, n.5, pp.295-299. ISSN 2078-5135.. BACKGROUND: Atherosclerosis that starts in childhood invariably advances during adulthood. AIM: We aimed to study the effect of obesity on main carotid artery intima-media thickness (CIMT) and arterial stiffness. MATERIAL AND METHODS: A total of 78 children were studied from October 2010 to February 2011. They were divided into obese (n=42, group 1) and normal (n=36, group 2). All children were subjected to physical examination, routine biochemical and haematological analysis, carotid ultrasonography and echocardiographic measurements. A detailed medical history was obtained. Body mass index (BMI) was calculated by dividing participants weight in kilograms by the square of their height in metres. Stiffness index β was calculated using blood pressure and diameter of the systolic and diastolic ...
Experiments in tissue culture using hydroxamic and phosphinic acid-based inhibitors show that MMPs are necessary for both maximal proliferation and migration of rabbit aortic SMCs.11 Furthermore, MMP inhibitors also prevent intimal migration of rat carotid artery SMCs after balloon injury in vivo.13 In rabbit SMCs, only gelatinases A and B are expressed in measurable quantities,11 which emphasize their role in modulating migration and proliferation in this model, which contains only SMCs. In the rat carotid artery, injury increases tissue levels of gelatinase B and activates gelatinase A,13 19 further implicating gelatinases in the response to injury. In the present study, we also investigated the expression of gelatinases after balloon injury, but in this case, a pig carotid artery model in which both deep medial tears and stretch-induced injury occur was used. Both types of injury are thought to be important in angioplasty restenosis in humans.34 Furthermore, we sought to investigate whether ...
The purpose of the study is to investigate the hemodynamic effect of calcified carotid plaque on blood flow in patients diagnosed with carotid artery disease. Two carotid artery models were generated based on a sample patient data, with normal and calcified carotid artery appearances. Circular calcified carotid plaque was found at the carotid bifurcation based on 3D computed tomography images. A computational fluid dynamics was performed to analyze the changes of blood flow in different situations. Our results showed that apparent turbulence was found in the diastolic phase at the carotid bifurcation in normal carotid artery geometry. In the presence of the calcified plaque, the flow velocity was increased to some extent, indicating the effect of plaque on hemodynamic changes. Wall shear stress was noticed to decrease at the aortic branches, and this indicates the potential risk of developing stenosis at this area. Our preliminary study demonstrates fluid structure interaction between calcified ...
Have you been told you have diseased or clogged carotid arteries (carotid stenosis)? Are you nervous about what this may mean in terms of your risk of stroke? Here are some answers to commonly asked questions regarding carotid artery disease.. What are the carotid arteries?. Carotid arteries are the two main blood vessels that supply most of your brain with blood.. What is a carotid bruit and does it definitely mean that the carotid is blocked?. A carotid bruit is a swooshing sound heard during a physical exam in which the physician listens to the sound of blood flow through the neck. When blood passes through a narrowing channel, it will give a very distinctive sound when heard through a stethoscope. Approximately 30 percent of patients with a carotid bruit will have a significant carotid blockage. However, carotid bruits are often associated with the presence of other atherosclerotic heart disease as well as other cardiovascular problems.. How is a carotid bruit assessed by my ...
Introduction and objectives The equations used in the general population to calculate cardiovascular risk are not useful in genetic hypercholesterolemia (GH). Carotid plaque detection has proved useful in cardiovascular prediction and risk reclassification but there have been no studies of its usefulness in GH. The aim of this study was to determine the association between the presence of carotid artery plaque and the occurrence of cardiovascular events in patients with GH.. Methods This study included 1778 persons with GH. The mean follow-up until the occurrence of cardiovascular events was 6.26 years. At presentation, the presence of carotid artery plaque was studied by high-resolution ultrasound.. Results Carotid artery plaque was found in 661 (37.2%) patients: 31.9% with familial hypercholesterolemia, 39.8% with familial combined hyperlipidemia, 45.5% with dysbetalipoproteinemia, and 43.2% with polygenic hypercholesterolemia. During follow-up, 58 patients had a cardiovascular event. Event ...
When narrowing occurs in the main arteries that flow to the brain, the condition is called "carotid artery disease". This can increase a persons risk of having a stroke, however, most people are unaware that they might have it!. Carotid duplex ultrasound, or an ultrasound of the carotid artery, is a simple and painless test performed in our office that easily detects carotid artery disease.. Treating carotid artery disease is focused on preventing a stroke, or if you have had a stroke, preventing any further strokes. Lifestyle changes are key in this battle. Sometimes medications are needed as well. Surgeries or stenting may be needed in certain people.. Carotid stenting is a minimally invasive procedure for certain appropriate people with carotid disease. A small metal mesh tube, or "stent", is placed in the artery to prop it open.. Discuss with one of our cardiologists to see if you are at risk for carotid artery disease.. ...
Childhood obesity is a major health problem throughout the world. Obese children are more likely to become obese adults in whom one can expect a higher rate of hospitalisation, interventions and premature death.1 In obese people, coronary heart disease generally manifests in middle age or later life. However, atherosclerosis has its roots in childhood, its first signs in obese children appearing before puberty; therefore, it is important to develop efficient strategies to reduce the incidence of cardiovascular disease (CVD) in the population. Carotid artery intima-media thickness (CIMT) serves as a marker of preclinical atherosclerosis.2. CVD develops as a result of arterial damage in the form of arteriosclerosis. Arteriosclerosis is a general term for conditions in which diffuse thickening and stiffening in mainly large- and medium-sized arteries develop under different conditions. Both the media and intima of the arteries could be involved in the pathology. Risk factors diagnosed in childhood ...
OBJECTIVE: The purpose of this study was to examine the association between adiposity measures, ultrasound image quality, and preclinical markers of atherosclerosis in young adults. METHODS: B-mode ultrasound was used to obtain common carotid intima-media thickness and common carotid artery distensibility of 2265 and 1313 adults aged 24 to 39 years in two population-based studies: the Cardiovascular Risk in Young Finns and Childhood Determinants of Adult Health studies. Qualitative assessments of ultrasound image quality were obtained from each study (scored as 1, excellent; 2, average; and 3, poor) based on the ability to detect arterial interfaces and the amount of noise present in the image. RESULTS: Increased adiposity was associated with significantly increased odds (all P | .05) of average or poor carotid ultrasound image quality. Reduced image quality was associated with lower intima-media thickness in Young Finns (regression coefficient = -0.029; P = .01) and higher intima-media thickness in
Carotid artery - What are the carotid arteries? Carotic Arteries. The human carotid arteries supply the head and the neck with oxygenated blood. The left common carotid artery originates from the aorta and the right common carotid originates from the brachiocephalic artery which originates from the aorta. The carotic artery divides in the neck to form the internal and external carotic arteries.
c) 2014, The Authors. Journal of Tissue Engineering and Regenerative Medicine (c) 2014 John Wiley & Son. This is the accepted version of the following publication: Luo, J, Ingham, E, Fisher, J, Homer-Vanniasinkam, S and Wilshaw, S-P (2014) The development of an acellular porcine carotid artery. In: Journal of Tissue Engineering and Regenerative Medicine. Tissue Engineering & Regenerative Medicine International Society, European Chapter Meeting, 10-13 June, 2014, Genova, Italy. Wiley , 335 - 336, which has been published in final form at http://dx.doi.org/10.1002/term. ...
D: Narrowing of the carotid artery by atherosclerosis, a common cause of stroke. ^^. A: Atheromatous plaque development in the region of the common carotid bifurcation.. A/R: Hypercholesterolemia, hypertension, DM and smoking are all strong risk ^^ factors for carotid artery disease.. E: Common, affecting men more than women with increasing incidence with age.. H: May be asymptomatic.. TIAs or CVAs (responsible for 25-30%).. Amaurosis fugax (temporary unilateral vision loss - like a curtain coming down caused by embolism into the ophthalmic artery, the first branch off the internal carotid artery).. E: Often normal. There may be a carotid bruit heard; however, this often does not reflect the degree of stenosis.. Signs of CVA (e.g. dysarthria, dysphasia, weakness in limbs). Signs of systemic vascular disease.. P: The carotid artery bifurcation is an area of the vascular tree where atherosclerosis is common. In combination with systemic risk factors, local haemo-dynamics, including low shear ...
carotid artery - MedHelps carotid artery Center for Information, Symptoms, Resources, Treatments and Tools for carotid artery. Find carotid artery information, treatments for carotid artery and carotid artery symptoms.
Increased arterial stiffness assessed by increase PWV and increased pulse pressure have been shown to relate directly with cardiovascular events.23,24 Similar prognostic information can be gained from BRS evaluation in different patient populations at risk for cardiovascular complications. Previous investigations have demonstrated that BRS is significantly related to carotid artery distensibility. A positive association between the elastic properties of the carotid artery and BRS has been reported in healthy volunteers,25 pregnant women,26 hypertensive subjects,27 and nondiabetic patients with carotid artery stenosis.28 However, in this study we did not observe any correlation between BRS and common carotid artery wall distensibility in T2DM patients with at least 2 additional cardiovascular risk factors.. This T2DM population differs significantly from previously published works. We have selected high-risk subjects with T2DM who are characterized by stiffened and diseased arteries as evidenced ...
Carotid artery morphological changes relate to the risk and presence of CAD in patients with suspected CAD. Additionally, the association of carotid artery morphological changes such as carotid artery plaque formation1,2 or stenosis3,4 with the extent of CAD has been reported. Although our observations are consistent with these studies, the study population was limited to patients with CAD with preserved LV function and did not include patients without CAD. In addition to the previous studies, we have shown that even in this selected population, carotid morphological changes are still useful and independent predictors of the extent of CAD and multivessel CAD.. A direct association between functional changes of artery and coronary atherosclerosis has been reported in previous studies.5,6 However, these studies concluded that this association was stronger for aortic stiffness than carotid arterial stiffness, suggesting that in the larger artery, stiffness could be a significant marker of the ...
To our knowledge, this is the first study to examine the accuracy with which central aortic systolic pressure can be estimated noninvasively in children. The method that we elected to compare invasive measures, carotid wall tracking, assumes carotid wall distension to be proportional to local intra-arterial carotid pressure and for carotid pressure to approximate aortic root pressure.15,16 Theoretically, tonometric measurements obtained at the carotid artery would be expected to perform as well as carotid wall tracking.10 However, in preliminary studies, we found that high-quality carotid tonometric recordings were more difficult to obtain than ultrasound wall tracking in children. We compared agreement between cSBP estimated from carotid wall tracking with measured cSBP in a heterogenous group of children in whom central hemodynamics would be expected to vary widely. Despite this, we observed good agreement between estimated and measured central aortic systolic pressures. This suggests that, in ...
One disclosed embodiment comprises a method for treating lesions in the carotid artery of a mammalian body. The method comprises transcervical access and blocking of blood flow through the common carotid artery (with or without blocking of blood flow through the external carotid artery), shunting blood from the internal carotid artery and treating the lesion in the carotid artery.
Introduction - Arterial stiffness is a major contributor to aging-related cardiovascular diseases. Pericardial fat (Pfat) may have a pathological effect due to its close proximity to the coronary arteries. However, no studies have examined whether Pfat is related to arterial stiffness.. Purpose - We examined the association between baseline measures of Pfat and carotid stiffness in 5768 participants (mean age, 62 yrs; 53% female; 39% Caucasian, 13% Chinese, 25% African American, and 23% Hispanic) from the Multi-Ethnic Study of Atherosclerosis, a prospective cohort study of 45- 84 yr-old men and women free of cardiovascular disease at baseline.. Methods - Pfat volume was assessed by computed tomography. Ultrasonography of the common carotid artery was used to calculate the distensibility coefficient (DC, a measure of compliance) and Youngs modulus (YM, a measure of stiffness). A lower DC and a higher YM are indicative of stiffer arteries. Multiple linear regression was used to determine the ...
New research from the Netherlands shows that older patients with chronic obstructive pulmonary disease (COPD) are at increased risk for carotid artery plaque formation and for the presence of vulnerable plaques with a lipid core, according to the American Thoracic Society. The cross-sectional study, part of the Rotterdam Study, an ongoing population-based cohort study examining the occurrence of and risk factors for chronic diseases in subjects aged 55 years and older, involved 253 patients with COPD and 920 patients without the condition. COPD was confirmed by spirometry. Participations with carotid wall thickening (intima-media thickness ≥ 2.5 mm) on ultrasonography underwent high-resolution MRI to characterize carotid plaques.. Participants with COPD had a twofold increased risk of carotid wall thickening on ultrasonography compared with controls. This risk increased significantly with the severity of airflow limitation. On MRI, vulnerable lipid core plaques were significantly more frequent ...
New research from the Netherlands shows that older patients with chronic obstructive pulmonary disease (COPD) are at increased risk for carotid artery plaque formation and for the presence of vulnerable plaques with a lipid core, according to the American Thoracic Society. The cross-sectional study, part of the Rotterdam Study, an ongoing population-based cohort study examining the occurrence of and risk factors for chronic diseases in subjects aged 55 years and older, involved 253 patients with COPD and 920 patients without the condition. COPD was confirmed by spirometry. Participations with carotid wall thickening (intima-media thickness ≥ 2.5 mm) on ultrasonography underwent high-resolution MRI to characterize carotid plaques.. Participants with COPD had a twofold increased risk of carotid wall thickening on ultrasonography compared with controls. This risk increased significantly with the severity of airflow limitation. On MRI, vulnerable lipid core plaques were significantly more frequent ...
Radcliffe Vascular peer-reviewed articles on carotid artery stenting, carotid artery endarterectomy, carotid artery disease, carotid artery stenosis, carotid
misc{3051799, abstract = {Cardiovascular diseases, such as atherosclerosis, is a major cause of mortality in, primarily, the western world. To be able to recognize early symptoms of this type of diseases it has proven to be important to investigate the mechanical properties of blood vessels. A few years back from now it became evident that the common carotid artery has a distinct bidirectional movement pattern in the longitudinal direction during each cardiac cycle. The mechanisms of this behavior has however since then been undetermined. In this study three independent indicators of the cardiac wall movements involvement is presented. By ultrasound examinations of both the right and left side common carotids and simultaneous examinations of left ventricle movement of the heart of 14 humans it has become evident that: The longitudinal movement in the carotid arterial wall, in both directions, occurs in parts of the vessel close to the heart before it is transmitted to more peripheral parts of ...
Ultrasound study to assess Carotid Intima Media Thickness in an office setting 525 patients to be enrolled at seven medical centers DALLAS - November 13, 2005 - SonoSite, Inc. (NASDAQ: SONO), the world leader in hand-carried ultrasound, announced today at the 2005 American Heart Association (AHA) Scientific Sessions that it is initiating a multi-center study to determine whether the addition of an ultrasound examination evaluating carotid artery wall thickness (CIMT), performed in the office setting, will provide a more effective tool for risk assessment and prevention of cardiovascular disease than current clinical methods alone. Over 20 years of clinical research has shown that the thickness (T) of the two innermost layers of the carotid artery wall, the intima (I) and media (M), begins to increase before plaque is evident within the vessel. This increased wall thickness is associated with an increased risk of cardiovascular disease, the leading cause of mortality and disability in the United States
Disease of the carotid artery is related to, in large part, the amount of atherosclerosis (or plaque) that is present in one of the main arteries to the brain-the Internal Carotid Artery (ICA. )Typically, the more plaque that is present, the narrower the diameter of the internal portion of the artery is that is delivering blood to the brain. One potential cause of stroke is the lack of enough blood flow to the brain that may be reduced as the inner diameter of the ICA get smaller. Alternatively, a piece of the plaque in the ICA could break away and travel to the brain lodging in a small artery producing a stroke by restricting blood flow (and oxygen) to a particular area of the brain.. While degree of narrowing within the carotid artery is a factor in determining whether intervention is required, the presence of symptoms related specifically to the carotid artery in question is another important factor to be considered. People may have a significant degree of narrowing of their ICA-in fact, it ...
The introduction of cerebral angiography in the 1930s by Moniz, followed by detailed postmortem studies of the cervical portion of the carotid artery in the 1950s by Miller Fisher, drew attention to the extracranial carotid arterys being more important than the middle cerebral artery in ischemic stroke (1). The description of the diagnostic features of carotid disease soon followed, and this led to strategies for preventing or eliminating carotid lesions. From the earliest writings, clinical investigators have debated a possible connection between severe carotid disease and impaired cognition. Few dispute the relationship between cognitive decline and large areas of infarction of cortex supplied by the carotid artery. The unsettled component is the causal relationship between mild cognitive decline and asymptomatic disease in the carotid artery that supplies the dominant hemisphere (the left carotid in 98% of right-handed individuals). In the presence of intellectual changes, should an ...
Introduction: It is unknown whether stroke risk is increased in the setting of large-artery atherosclerotic plaque that does not cause significant luminal stenosis.. Hypothesis: We hypothesized that the prevalence of vulnerable, non-stenosing carotid artery plaque on the side ipsilateral to an acute brain infarction would be higher than on the contralateral side.. Methods: Using a prospective stroke registry, we identified patients with acute infarction limited to the vascular territory of one internal carotid artery (ICA) and no large-vessel atherosclerosis based on the common criterion of greater than or equal to 50% luminal stenosis. We used magnetic resonance angiography to ascertain vulnerable ICA plaque, as defined by the presence of intraplaque high-intensity signal (IHIS). We used McNemars test for correlated proportions to compare the prevalence of IHIS on the side ipsilateral to acute infarction versus the contralateral side within individual subjects.. Results: We analyzed 218 ...
TY - GEN. T1 - Multi-scale AM-FM motion analysis of ultrasound videos of carotid artery plaques. AU - Murillo, Sergio. AU - Murray, Victor. AU - Loizou, C. P.. AU - Pattichis, C. S.. AU - Pattichis, Marios. AU - Barriga, E. Simon. PY - 2012. Y1 - 2012. N2 - An estimated 82 million American adults have one or more type of cardiovascular diseases (CVD). CVD is the leading cause of death (1 of every 3 deaths) in the United States. When considered separately from other CVDs, stroke ranks third among all causes of death behind diseases of the heart and cancer. Stroke accounts for 1 out of every 18 deaths and is the leading cause of serious long-term disability in the United States. Motion estimation of ultrasound videos (US) of carotid artery (CA) plaques provides important information regarding plaque deformation that should be considered for distinguishing between symptomatic and asymptomatic plaques. In this paper, we present the development of verifiable methods for the estimation of plaque ...
In the normal vascular system, the extracellular matrix (ECM), a complex network of various proteins and proteoglycans, is maintained by an intricate balance between synthesis and degradation of its structural components. Maintenance of tissue integrity during normal development and growth is achieved by programmed remodeling of the matrix, involving numerous enzymes as well as specific inhibitors that keep their activity in check. The MMPs are a family of at least 12 zinc-dependent endoproteinases that function at neutral pH and cooperatively hydrolyze most of the proteins in the ECM. In this study, the temporal expression and activity of members of the MMP family and one specific inhibitor, TIMP-1, have been examined using the balloon catheter-induced injury model in the rat carotid artery.. Unlike in the human, there are no smooth muscle cells (SMCs) in the intima of a normal rat carotid artery.19,20 SMCs resident in the media are surrounded by a basal lamina and anchored to the ECM. After ...
Noninvasive imaging of carotid artery plaque with MRI can accurately predict future cardiovascular events like strokes and heart attacks in people without a history of cardiovascular disease, according to a new study published online in the journal Radiology.. Researchers have long known that some arterial plaque is more dangerous because of its vulnerability to rupture. MRI can discern features of vulnerable plaque, such as a lipid core with a thin fibrous cap. This ability makes MRI a potentially valuable tool for identifying patients at risk for subsequent cardiovascular events.. To study the predictive value of MRI plaque imaging, researchers performed carotid artery ultrasound and MRI on 946 asymptomatic patients from the Multi-Ethnic Study of Atherosclerosis (MESA). The carotid arteries are the large vessels located on each side of the neck that carry oxygenated blood to the front part of the brain. They are highly accessible for imaging, and their condition tends to mirror that of the ...
This 3D stock medical animation shows the progression of a left carotid artery occlusion which results in a cerebral infarct (stroke). The animation opens with a generic (blue) figure with the brain and major arteries shown. The camera then zooms into a detailed cut-section through the left carotid artery bifurcation. As blood flows to the brain, an occlusion forms cutting off the circulation resulting in the subsequent death of the brain tissue.
Figure 1 Intraluminal Thrombus. Right carotid angiogram just prior to carotid artery stenting (CAS) showed severe stenosis (arrow) of the internal carotid artery (A). Cross sections by optical coherence tomography (OCT) (B) demonstrated large thrombus as a backscattering protrusion into the carotid lumen with signal free shadowing (white arrow). Intravascular ultrasound (IVUS) (C) showed eccentric and low-echoic plaque, but did not discriminate this thrombus from other tissue components. T1 weighted images of black-blood magnetic resonance imaging (MRI) (D) showed severe stenosis with high intensity spot without clear margin (blue arrow). In this patient, carotid endarterectomy was performed instead of CAS because a large intraluminal thrombus was clearly demonstrated by an OCT. Post-operative pathological analysis with Hematoxylin and Eosin staining (E) demonstrated a large intraluminal red thrombus (blue arrow) in the carotid artery. The bar (B, C, D, and E) equals 2 mm. This patient was ...
Patients will be chosen for the study based on presence of carotid artery stenosis ascertained by CTA and carotid artery ultrasound. Patients will receive and intravenous injection of the radiolabeled PET tracer,[F-18]RGD-K5, and will undergo PET imaging of their carotid arteries bilaterally. PET images will be analyzed to determine the standard uptake value (SUV) of [F-18]RGD-K5 uptake by the carotid artery plaque and this will be compared to the SUV of the background (blood pool in the aorta). This will be expressed as a target to background ratio (TBR). Investigators expect to find a significant uptake of [F-18]RGD-K5 by carotid artery palque and investigators therefore expect to find a TBR that is significantly ,1. Investigators also expect to find that plaque from patients who show a TBR ,1 will also be enriched for histologic markers for inflammation and angiogenesis ...
Carotid artery disease occurs when plaque, a build-up of fat, cholesterol and other substances, collects and forms along the walls of the carotid arteries. This buildup of plaque and the injury it causes is called atherosclerosis.. Over time, the walls of affected arteries thicken and become stiff and the blood vessel may also become narrowed, a condition called stenosis, limiting blood flow.. Left untreated, carotid artery disease increases the risk for stroke. A stroke occurs when blood flow to the brain is obstructed by plaque or blood clots, when bits of plaque break free and travel to smaller arteries in the brain, or when a blood vessel in the brain ruptures. A lack of oxygen and other essential nutrients may cause permanent damage to the brain or death.. ...
BACKGROUND:. Atherosclerotic vascular disease is a major source of morbidity and mortality. Inflammation plays an important role in atherosclerosis. The tools to systematically study the extent to which genetic variation determines risk of and progression of atherosclerosis are only now becoming available.. DESIGN NARRATIVE:. The study will evaluate the role of genetic variation in inflammatory pathway genes at 29 loci on the risk and progression of carotid artery atherosclerotic disease (CAAD). Genes to be evaluated include those potentially involved in plaque initiation and progression. The investigators will evaluate single nucleotide polymorphisms (SNPs) informative for the common locus haplotypes. Choice of informative polymorphisms for evaluation is based on the genes evolutionary history. They will evaluate progression effects in subjects with CAAD followed longitudinally by noninvasive magnetic resonance (MR) techniques over 3 years. Risk will be evaluated by case-control comparisons. ...
A CT heart scan is used to diagnose blockage or narrowing of the carotid arteries of the neck and/or the branches of the carotid artery. Plaque build up, blood clots, calcium deposits and other substances in the blood stream may cause an interruption in the blood flow through the carotid arteries.
Improve your skills on carotid artery stenting procedures!. You will be able to learn more about carotid artery access: femoral, brachial, radial. Learn about carotid artery protection during procedures: different filters used, and reversal of flow (moma technique), and different stents placed in the internal and common carotid. Youll also learn about the role of a new micro mesh carotid stent. Dont hesitate to give us your feedback. ...
The principal finding of this study was that, among a variety of noninvasively assessed morphological and functional carotid artery parameters, only plaque burden consistently predicted both all-cause and cardiovascular mortality. Blood pressure variables, heart rate, IMT, and lumen diameter were not predictive, and among various stiffness indexes, only YEM was associated with cardiovascular but not all-cause mortality. The relation with traditional risk factors seemed very modest.. Potential limitations need to be considered. Predictors of all-cause and cardiovascular mortality were derived with stringent statistical criteria, yet the limited number of events may have restrained statistical power. The effect of a single baseline measurement on future events is subject to regression dilution.22 Hence, we may have underestimated the true associations with mortality. Calculating stiffness parameters from brachial rather than carotid PP may have introduced a bias23,24 that is known to depend on ...
We use stenting, which involves the placement of a tiny tube into your carotid artery, to treat abdominal aortic aneurysm, carotid artery disease, peripheral vascular disease.
Objetivo: analisar o espessamento intimal adjacente ao implante de um stent em artérias carótidas de suínos e aquele secundário à simples manipulação da artéria pelo introdutor do dispositivo. Métodos: sete suínos receberam o implante de um stent na artéria carótida comum direita, sob dissecção direta do vaso e sete animais controles sofreram manipulação arterial, com o sistema introdutor, sem o implante do stent. As artérias carótidas comuns contralaterais não lesadas, dos dois grupos, também foram utilizadas como controle. Realizada a análise morfométrica de amostras de tecido arterial, obtidas junto ao segmento distal do stent, quatro semanas após o implante. Os achados morfométricos foram comparados com amostras arteriais oriundas das carótidas lesadas, no grupo controle, e das carótidas contralaterais não lesadas dos dois grupos. A análise estatística foi realizada através do teste de Mann-Whitney e do teste T de Wilcoxon, para amostras não-paramétricas ...
You are invited to attend a free ultrasound screening for Carotid Artery Disease on Wednesday, May 28, from 9 a.m. to noon. The screening will be administered by the Pen Bay Vascular Lab under the direction of Dr. Julie White at Pen Bay Surgery located in the Physicians Building, Suite 103 on the Pen Bay Medical Center campus.. Carotid Artery disease is the most common cause of stroke. When this disease is detected early, stroke can be prevented. See your doctor. Discuss lifestyle changes. Consider getting an ultrasound exam. A few small steps may save your life.. You are eligible to participate in this screening if you have all these risk factors:. · Are age 60 or over.. · Are currently a smoker, have a smoking history (100 cigarettes or more) or have had prolonged exposure to second-hand smoke.. · Have elevated cholesterol and/or high blood pressure.. · Have a family or personal history of coronary artery disease.. The event is free and open to the public, but space is limited. Call us ...
Carotid artery stenting is a procedure to open up a narrowed carotid artery. Two carotid arteries on each side of the neck deliver blood to the brain. A stent is a tiny, metal mesh coil that props open the artery so that blood can flow freely. During the procedure, your doctor inserts a long thin tube called a catheter into an artery. This lets the doctor move instruments through the artery to put the stent in place. Stenting is often done with a procedure called angioplasty. For angioplasty, the doctor inflates a tiny balloon at the tip of the catheter at the blocked portion of the artery. The inflated balloon presses the plaque against the artery wall thereby opening the artery for better blood flow. The doctor then places the stent to help keep the artery open. ...
Psychology Definition of CAROTID ARTERY: An artery found in the side of the neck on both sides that leads to the head and to the brain.
Surgery to treat carotid artery dissection (a tear in the carotid artery) is usually a minimally invasive procedure, according to the Cleveland Clinic. Minimally invasive surgery generally causes...
MRI Based on T2 Mapping An MRI scan can determine the size of a plaque in the carotid arteries, but cannot [MORE]
MRI of the CAROTID ARTERIES Review Pathogenesis/Progression Intima-Media Thickness (IMT) Studies Plaque Constituents Morphology Stable vs Unstable (Vulnerable) Survey of Methods and Results Most Published Results - 1.5T Recent 3T Carotid MRI Studies
The heterogeneity of atherosclerotic tissue has limited comprehension in proteomic and metabolomic analyses. To elucidate the functional implications, and differences between genders, of atherosclerotic lesion formation we investigated protein profiles from different regions of human carotid atherosclerotic arteries; internal control, fatty streak, plaque shoulder, plaque centre, and fibrous cap. Proteomic analysis was performed using 2-DE with MALDI-TOF, with validation using nLC-MS/MS. Protein mapping of 2-DE identified 52 unique proteins, including 15 previously unmapped proteins, of which 41 proteins were confirmed by nLC-MS/MS analysis. Expression levels of 18 proteins were significantly altered in plaque regions compared to the internal control region. Nine proteins showed site-specific alterations, irrespective of gender, with clear associations to extracellular matrix remodelling. Five proteins display gender-specific alterations with 2-DE, with two alterations validated by nLC-MS/MS. ...
The primary objective of this cadaveric study was to review the morphological variations of the anatomy of the human carotid artery bifurcation relevant to carotid endarterectomy (CEA) and carotid artery stent-supported ...
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misc{6255e459-8fcc-46d0-a460-4291149361a2, abstract = {Background: Previous studies from our and other centers on young patients with type 1 diabetes (T1D) have indicated pro-atherosclerotic changes in the carotid arteries and in the lipid and systemic inflammatory profiles without a clear relationship between these changes and the hyperglycemic control. We have also earlier found in these patients a certain HLA-related genetic susceptibility to adverse vascular changes.,br, Objective: To assess whether pro-atherosclerotic changes are present in apparently healthy first- degree relatives of patients with T1D.,br, Methods: Plasma lipids, C-peptide (index of insulin secretion), C-reactive protein (CRP), and the carotid artery intima-media thickness (CA-IMT), compliance (CAC) and stiffness index (SI) were assessed in up to 116 non-diabetic first-degree relatives (FDR; mean age: 12.6 years; 56 female) of patients with T1D and in up to 43 age-matched control individuals (mean age: 13.3 years; 23 ...
The carotid artery is one of the major arteries of the human body. It helps blood flow to and from a humans heart. In human anatomy, the left and right common carotid arterie are arteries that supply the head and neck with oxygenated blood.. ...
Objective. Preliminary evidence suggests that ankylosing spondylitis (AS) is associated with an increased cardiovascular (CV) risk. We investigated subclinical atherosclerosis and arterial stiffness in patients with AS compared with controls, and identified CV and AS related risk factors for atherosclerotic disease.. Methods. A total of 59 patients with AS who were scheduled for etanercept treatment according to the ASsessments in Ankylosing Spondylitis guidelines and 30 healthy controls were recruited. Subclinical atherosclerosis was assessed as the average intima-media thickness (IMT) of the common carotid artery. Arterial stiffness was determined by distensibility, compliance, and Youngs elastic modulus of the carotid artery.. Results. AS patients had a greater IMT (0.62 ± 0.09 mm vs 0.57 ± 0.09 mm in controls; p = 0.02), a difference that remained after adjustment for traditional CV risk factors. AS was associated with higher carotid pulse pressure (47 ± 7 mm Hg vs 44 ± 8 mm Hg in ...