Eosinophil peroxidase and myeloperoxidase use hydrogen peroxide to produce hypobromous acid and hypochlorous acid. These powerful oxidants may damage the lungs if they are produced as part of the inflammatory response in asthma. The aim of this study was to determine if peroxidases generate hypohalous acids in the airways of individuals with stable asthma, and if they affect lung function. Sputum was induced from patients with mild to moderate asthma and from healthy controls. Eosinophil peroxidase, myeloperoxidase, chlorinated and brominated tyrosyl residues, and protein carbonyls were measured in sputum supernatants. Eosinophil peroxidase protein was significantly elevated in asthmatic subjects whereas myeloperoxidase protein was not. There was significantly more 3-bromotyrosine (Br-Tyr) in proteins from the sputum of asthmatics compared to controls (0.79 vs. 0.23 mmol Br-Tyr/mol Tyr; medians p , .0001). Levels of 3-chlorotyrosine (0.23 vs. 0.14 mmol Cl-Tyr/mol Tyr; medians p = .11) and ...
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NTP STATISTICAL ANALYSIS OF NON-NEOPLASTIC LESIONS REPORT: PEIRPT10 LAB: Battelle Columbus WATER DISINFECTION MODEL (SODIUM BROMATE) DATE: 12/08/03 EXPERIMENT: 97013 TEST: 92 TIME: 14:32:25 TEST TYPE: 26-39 WEEKS CAGES FROM 0000 TO LAST CAGE PAGE: 1 CONT: N01-ES-65406 ROUTE: SKIN APPLICATION NTP C#: 97013B PATHOLOGIST: TOFT, JOHN CAS: 7789-38-0 ------------------------------------------------------------------------------------------------------------------------------------ FINAL#1 MICE REASONS FOR REMOVAL: 25019 Moribund Sacrifice 25020 Natural Death 25021 Terminal Sacrifice REMOVAL DATE RANGE: ALL TREATMENT GROUPS: INCLUDE ALL NTP STATISTICAL ANALYSIS OF NON-NEOPLASTIC LESIONS REPORT: PEIRPT10 LAB: Battelle Columbus WATER DISINFECTION MODEL (SODIUM BROMATE) DATE: 12/08/03 EXPERIMENT: 97013 TEST: 92 TIME: 14:32:25 TEST TYPE: 26-39 WEEKS CAGES FROM 0000 TO LAST CAGE CONT: N01-ES-65406 ROUTE: SKIN APPLICATION NTP C#: 97013B PATHOLOGIST: TOFT, JOHN CAS: 7789-38-0 SUMMARY OF STATISTICALLY ...
A new nitro derivative of β-naphthol was synthesized. Its structure was studied by ¹HMR and IR spectrometry. A possibility of its use for immobilization on fibrous substrates and application as a specific analytical reagent for the determination of metal ions, in particular, cobalt(II) ions, was shown. The absorbance maximum of the reagent is at 490 nm and of the complex with cobalt ions, 690 nm ...
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Lead(II) iodate 99.99% trace metals basis; CAS Number: 25659-31-8; EC Number: 247-168-3; Synonyms: Lead iodate (Pb(IO3 )2 ),Lead diiodate; Linear Formula: Pb(IO3)2; find Sigma-Aldrich-435880 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich
Into a 4L reactor was added at room temperature Compound 8 (229g, 820mmol, leq) and 2N sulfuric acid (1147mL, 112g sulfuric acid, 1.147mol, 1.4eq). The reaction light yellow mixture was stirred and sodium bromate (126g, 836mmol, 1.02eq) was added. The mixture became yellow and the temperature dropped (endothermic dissolution). After 30min the reaction temperature reached 35°C and heated further to 40°C for 6h to give dark yellow solution with precipitate in the bottom of reactor. Toluene (2L) and NaOH (24%, 546g, 131g NaOH, 3.28mol, 4.0eq) were added and the reaction mixture was vigorously stirred for 1 hour at 42°C. The reaction mixture was then poured into a 4 L separation funnel. The dark water phase was discarded and the dark red organic phase was washed with 1.1L 5% sodium sulphite solution and 1L 20% brine. The organic phase was then concentrated on a rotavapor (50°C, 90-65 mbar, finally at 45mbar) to give l l lg dark red oil with crystals in the flask. A GC analysis (5mg red oil ...
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Enthaply Berkeley is looking for an Analyst I for our Ion Chromatography and TOC analysis. The shift is from Mon- Friday, 10am-6:30pm. Analysts perform chemical measurements and other tasks to meet the expectations of our clients by efficiently and profitably generating defensible data on time.. Roles and Responsibilities:. • Quantitative sample analysis by Ion Chromatography and TOC. • Preparation of data summaries for inclusion in client reports. • Sample and standard preparation. • Instrument calibration and validation. • Instrument maintenance and troubleshooting. • Maintaining organized records of sample preparation and analysis, equipment maintenance and data collected off site. • Maintain consumables and parts for instruments. • Overhead projects designed to improve efficiency of, or accuracy of analyses. • Communicating relevant updates to applicable people in a timely manner. • Performing other duties and responsibilities as prescribed by the Company. • Compliance ...
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EAG Laboratories employs Ion Chromatography (IC), a high-throughput and versatile technique to analyze either positive or negative ions.
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The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database ...
What kind of information would you need to demonstrate that the substance responsible for increasing the rate of this reaction is an enzyme? Explain how this information would indicate that the catalytic effect is due to an enzyme ...
Potassium iodate is used to add iodine to salt. It is better than potassium iodide because it does not oxidize to iodine and evaporate like potassium iodide does. It is sometimes used in flour just like potassium bromate. It is also used for radiation protection. A nuclear explosion can make radioactive iodine, which goes into the thyroid and can make cancer. Eating potassium iodate makes the thyroid full of nonradioactive iodine and prevents radioactive iodine from going in. It lasts longer than potassium iodide. ...
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TY - JOUR. T1 - The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages. AU - Lane, Amanda E.. AU - Tan, Joanne T.M.. AU - Hawkins, Clare L.. AU - Heather, Alison K.. AU - Davies, Michael J.. N1 - Copyright: Copyright 2010 Elsevier B.V., All rights reserved.. PY - 2010/8/15. Y1 - 2010/8/15. N2 - MPO (myeloperoxidase) catalyses the oxidation of chloride, bromide and thiocyanate by hydrogen peroxide to HOCl (hypochlorous acid), HOBr (hypobromous acid) and HOSCN (hypothiocyanous acid) respectively. Specificity constants indicate that SCN- is amajor substrate for MPO. HOSCN is also a major oxidant generated by other peroxidases including salivary, gastric and eosinophil peroxidases. While HOCl and HOBr are powerful oxidizing agents, HOSCN is a less reactive, but more specific, oxidant which targets thiols and especially low pKa species. In the present study we ...
Calcium iodates are inorganic compound composed of calcium and iodate anion. Two forms are known, anhydrous Ca(IO3)2 and the hexahydrate Ca(IO3)2(H2O). Both are colourless salts that occur naturally as the minerals called lautarite and bruggenite, respectively. A third mineral form of calcium iodate is dietzeite, a salt containing chromate with the formula Ca2(IO3)2CrO4. Lautarite, described as the most important mineral source of iodine, is mined in the Atacama Desert. Processing of the ore entails reduction of its aqueous extracts with sodium bisulfite to give sodium iodide. Via a comproportionation reaction, the sodium iodide is combined with the iodate salt to produce elemental iodine. Calcium iodate can be produced by the anodic oxidation of calcium iodide or by passing chlorine into a hot solution of lime in which iodine has been dissolved. Calcium iodate can also be used as an iodine supplement in chicken feed. Calcium iodate is used in the manufacture of disinfectants, antiseptics, and ...
In the present work, a simple and rapid method for determination of iodate is described. Iodometric reaction between iodate, excess iodide, and acid has been used, and the iodine liberated is allowed to react with variamine blue (VB) dye in the presence of sodium acetate to yield a violet-colored species. A calibration curve was obtained in the concentration range of 2 to 30 μg of iodate in a final equilibration volume of 10 mL. The effect of different interfering anions on determination of iodate was also studied. The developed method was applied to iodate determination in various iodized salt samples obtained from local markets in and around Pune city, India. The amount of iodate in various table salt samples was in the range of 10 to 25 ppm.
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NTP Experiment-Test: 97013-94 INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a) Report: PEIRPT03 Study Type: 26-39 WEEKS WATER DISINFECTION MODEL (SODIUM BROMATE) Date: 12/08/03 Route: DOSED WATER Time: 14:40:44 FINAL#1 MICE Facility: Battelle Columbus Laboratory Chemical CAS #: 7789-38-0 Lock Date: 07/30/01 Cage Range: All Reasons For Removal: All Removal Date Range: All Treatment Groups: Include All a Number of animals examined microscopically at site and number of animals with lesion Page 1 NTP Experiment-Test: 97013-94 INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a) Report: PEIRPT03 Study Type: 26-39 WEEKS WATER DISINFECTION MODEL (SODIUM BROMATE) Date: 12/08/03 Route: DOSED WATER Time: 14:40:44 ____________________________________________________________________________________________________________________________________ TGAC (FVB/N) HEMIZYGOUS FEMALE 0 MG/L 80 MG/L 400 MG/L 800 MG/L ...
Ion Chromatography market research report covering industry trends, market share, market growth analysis and projection by MIcroMarketMonitor.com. Ion Chromatography market report includes,|Key question answered| What are market estimates and forecasts; which of Ion Chromatography markets are doing well and which are not? and |Audience for this report| Ion Chromatography companies.
The usefulness of Tb4O7 nanoparticles (NPs) as analytical reagents using sensitized luminescence as a detection system is described for the first time, and the results obtained are compared with t ...
Palladium chloride, aswell accepted as aegis dichloride, aegis chloride, anhydrous chloride, toxic, for advancing a appropriate catalyst, the atomic sieve; the alertness of non-conductive actual coating; assembly of gas sensors, analytic reagents. The red-brown apparent powder, baffling in water, hydrochloric acid, ethanol, acetone and hydrobromic acid. For assurance of palladium, mercury, thallium and iodine, attenuate…
Describes recent advances in ion chromatography and demonstrates how it is used to solve scientific and industrial problems. The basic principles of ion chromatography are explained, including gradient elution of ions and micromembrane suppressors. The various anion and cation exchange columns together with various detection methods and applications of ion chromatography in the .
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An olefin polymerization and copolymerization catalyst active in the presence of an alkyl aluminum cocatalyst is prepared by mixing, in the presence of a solvent, particles of a silica or alumina material having reactive surface groups, and a complex of the general formula (MgR2)m (AlR3 )n where R and R are alkyl groups and m/n is between about 0.5 and 10, inclusive, to form a hydrocarbon insoluble reaction product which is then mixed, in the presence of a solvent, with a titanium, vanadium or zirconium halide, oxyhalide or alkoxyhalide, followed by evaporation of the solvent.
Article Direct injection ion chromatography for the control of chlorinated drinking water: simultaneous estimation of nine haloacetic acids and quantitation of ...
Ion Chromatography is especially suited for the separation of inorganic ions, metal complexes and low molecular weight organic species. It is used intensively in environmental analysis. In the Topic Outline you will see how I think to develop this Topic. Mail me if you have any comments or suggestions ...
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Analytica EBC - Soluble Nitrogen of Malt: Spectrophotometric Method - The determination of soluble nitrogen in unhopped wort from malt by spectrophotometry It is necessary to use nbsp EBC Methods and
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Eosinophil peroxidase is an enzyme found within the eosinophil granulocytes, innate immune cells of humans and mammals. This oxidoreductase protein is encoded by the gene EPX, expressed within these myeloid cells. EPO shares many similarities with its orthologous peroxidases, myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO). The protein is concentrated in secretory granules within eosinophils. Eosinophil peroxidase is a heme peroxidase, its activities including the oxidation of halide ions to bacteriocidal reactive oxygen species, the cationic disruption of bacterial cell walls, and the post-translational modification of protein amino acid residues. The major function of eosinophil peroxidase is to catalyze the formation of hypohalous acids from hydrogen peroxide and halide ions in solution. For example: H2O2 + Cl− → HOCl + H2O Hypohalous acids formed from halides or pseudohalides are potent oxidizing agents. The open reading frame of human eosinophil peroxidase was ...
The stabilities and speciation of the halamines in water are difficult to characterize experimentally. We provide theoretical estimates of aqueous standard free energies of formation for inorganic chloramines, bromamines, and bromochloramines, based on high-accuracy theoretical standard free energies of formation in gas phase combined with quantum chemical estimates of Henrys law constant. Based on comparisons between several theoretical and experimental datasets, we assign an error of 1.1-1.2 log unit for equilibrium constants of several reactions leading to halamines in water. The reactions of ammonia with HOCl or HOBr that lead to dichloramine, trichloramine, and tribromamine are found to be thermodynamically more favorable than was previously believed. The newly reported equilibrium data also allow us to propose rate constant values for some hydrolysis and disproportionation reactions of dichloramine, monobromamine, and bromochloramine. Finally, theoretical results indicate aqueous acid
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Monmouth College recently received $10,000 from the Pittsburgh Conference Memorial National College Grants Program to purchase ion chromatography equipment.. Monmouth College recently received $10,000 from the Pittsburgh Conference Memorial National College Grants Program to purchase ion chromatography equipment.. The instrument can be used to test water quality in chemistry labs, educate biochemistry students and facilitate collaboration between the chemistry and biology-environmental studies departments. The equipment also will be used in the Monmouth Coffee Project, an interdisciplinary science and business collaboration.. Monmouth College will match the grant from its pool of science funds earmarked for chemistry.. ...
Simple and Rapid Spectrophotometric Determination of Titanium on Etched Aluminum Foils. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
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HPLC is not suitable for analyses of standard ions or cations in water and various foods. For these analyses, ion chromatography (IC) is the method of choice.
Ion chromatography does not require sample derivatization and little to no sample preparation. It allows for minimal handling of toxic reagents and does not generate any hazardous chemical waste. Sample integrity and stability is maintained and the sample can be simply reconstituted in water and directly injected.|br /|
Haddad, PR (1991) Foreword to the Proceedings of International Ion Chromatography Symposium, San Diego, CA 1990. Journal of Chromatography A, 546. p. 1. ISSN 0021-9673 ...
The principal findings were as follows: 1) C-fiber function, as assessed by the LDIflare technique, is severely impaired in CN and indistinguishable from DPN alone; 2) MMH is relatively preserved in CN and significantly higher than in neuropathy alone; and 3) affected and unaffected limbs of patients with CN have similar C-fiber dysfunction and MMH.. The reduced MMH in the DPN group is not unexpected, having been described in a variety of diabetic states including impaired glucose tolerance (6-8). What is surprising is the relative preservation of MMH in the DCN groups, as this would be expected to be worse or similar to, but not significantly better than, the relatively less complicated DPN group. The latter findings are supported by other studies (13,14).. As first suggested by Charcot (9,10), bone resorption as a result of increased bone perfusion secondary to the sympathetic denervation may be implicated in the development of CN (11). Preservation of the MMH in CN is consistent with ...
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