GROBLER, GP; DOWER, BJ; NORTJE, MB e WALTERS, J. The results of a cementless acetabular component combined with impaction bone grafting in patients with acetabular protrusion. SA orthop. j. [online]. 2012, vol.11, n.3, pp.29-33. ISSN 2309-8309.. We undertook this study to determine the results of acetabular fixation using the Duraloc 300 uncemented acetabular component combined with impaction bone grafting in patients with acetabular protrusion. Forty-two consecutive total hip replacements using a Duraloc 300 cup in patients with acetabular protrusion requiring impaction bone grafting were reviewed at an average of 6.3 years. In no cases were structural graft, wire mesh or cages utilised. Pre-operative X-rays were analysed for degree of protrusion. Post-operative X-rays were analysed for cup placement including centre of rotation and interface gaps. Follow-up films were analysed for graft incorporation, lucent lines, osteolysis, wear and migration. Kaplan-Meier survivorship analysis was ...
Purpose: To evaluate the effectiveness and limitations of autologous osteochondral grafting for the treatment of articular cartilage defects in the knee. Methods: The subjects were 40 patients who had undergone autologous osteochondral grafting. Fifteen knees had cartilage defects combined with anterior cruciate ligament tears (ACL group), 15 knees had cartilage defects combined with osteoarthritis (OA group), and 10 knees had cartilage defects combined with osteochondral dissecans (OCD group). From one to five osteochondral pegs were harvested from the less-weight-bearing periphery of the articular surface of the femoral condyle and grafted to cartilage defects. The clinical results were assessed based on the Lysholm score and radiographic and magnetic resonance imaging (MRI) image assessment. Results: The median follow-up duration was 24 months (range from 12 to 41 months). The mean Lysholm score following treatment was improved in all groups. The patients who had cartilage defects combined ...
|p|This video details our technique of osteochondral allograft transplantation for the treatment of articular cartilage defects of the knee. The content includes the indications and contraindications of osteoarticular allograft transplantation, patient positioning, surgical technique, outcomes, and postoperative management.|/p|
Impaction grafting is controversial in the presence of segmental and cavitary acetabular defects and requires the use of supplemental devices to close segmental defects. This approach, however, would allow treating combined deficiencies that could not be managed with impacted cancellous bone alone. We raised the following two questions: (1) What is the survival rate in patients with combined deficiencies reconstructed with metal mesh, impaction grafting and a cemented cup and (2) can metal mesh prevent cup migration? We evaluated 23 cavitary uncontained acetabular defects in revision hip arthroplasty. Preoperative diagnoses were aseptic loosening (19 hips) and second-stage reimplantations after resection for infection (four hips). The preoperative Merle DAubigné-Postel score averaged 7.4 points. Two patients had reoperations for mechanical failure at 6 and 24 months. The survival rate with further revision as an end point was 90.8% at an average of 36 months (range, 24-56 months; 95% ...
Each type of graft material has its benefits. Your periodontist can help you decide which sinus augmentation material is right for you.. Autogenous bone grafts are the historical standard of bone grafting materials. Since the bone comes from your own body, your immune system will readily accept the transferred cells. Because your periodontist will harvest the bone cells from your body, usually from the hip or the tibia bone just below the knee, autogenous bone grafts require two surgeries. Autogenous bone grafts may be the right approach to sinus augmentation for you if you are willing to undergo two procedures and are concerned about rejection.. Allograft or xenograft may be right for you if you prefer to avoid the first procedure to harvest bone cells. During an allograft bone graft, our periodontist will transfer purified bone from a human cadaver. In xenograft, bone will serve as a scaffold onto which your body will grow new bone cells.. Sinus augmentation may be right for you if you are ...
The purpose of this study is to investigate quantitative vascular cone beam CT(CBCT) in a clinical pilot of patients that have received a structural allograft for bone cancer or a vascularized structural autograft for bone cancer or traumatic injury. Development of a minimally invasive, longitudinal outcome measure to quantify intramedullary vascular volume and cortical bone volume of structural allografts in patients is required to translate revitalizing structural allograft in clinical trials. Our novel vascular CBCT will be able to demonstrate the significant differences between vascularized fibular autografts vs. structural allografts in patients that will undergo structural grafting. These data will be used to devise a power calculation for a definitive clinical trial to evaluate the efficacy of the revitalizing allograft ...
Most acetabular revisions are managed with cementless hemispherical or elliptical metal implants relying on bone ingrowth. Nonetheless, loss of acetabular bone stock and inability to achieve secure component fixation represent challenges in the setting of revision total hip arthroplasty. Impaction bone grafting (IBG) using allograft represents one option for treatment of this problem. However, cup migration and bone graft resorption are limitations when IBG is used for large segmental defects, and the precise role of IBG as well as the use of mesh (and the kinds of defects for which mesh does not work well) in this setting remains unknown.. ...
Distal comminuted femoral fractures with joint involvement are highly challenging for the surgeon. We present a potential therapeutic concept that aims especially at the treatment of posttraumatic leg length discrepancy. This case report describes a polytraumatized 19-year-old German woman. Among other injuries she had a third grade open distal comminuted femoral fracture with a long distance metaphyseal osseous defect. As a primary care procedure an external fixation was applied at first. On day 13, an open reconstruction of her distal femur and the articular surface was performed by screw osteosynthesis, shortening and intramedullary nailing. Due to delayed osseous consolidation an autologous cancellous bone grafting was performed twice. In addition to the second cancellous bone graft an allogeneic cortical bone graft was implemented. A 6.5cm posttraumatic leg length shortening after osseous consolidation was the result. The entire leg length shortening was successfully treated 16 months after her
 Background: Massive bone allograft is an option in cases of limb preservation and reconstruction after massive benign and malignant bone tumor resection. The purpose of this study was to analyze the outcome of these procedures at Imam Reza Hospital, Mashhad University of Medical Sciences. Methods: In this study, 113 cases have been presented. Eleven cases were excluded (patients has a traumatic defect or they passed away before the completion of the study�s two-year follow up period). Each patient completed a questionnaire, went through a physical examination and, if indicated, X-ray information was collected. The patients were divided into three groups: chemotherapy, chemotherapy plus radiation therapy, and no-adjuvant-therapy. Results: Fifty-four cases were male and the mean age was 24.5±5.39. The number of cases and indications for surgery were: 33 cases of aggressive benign tumors or low grade malignant bone tumors (large bone defects) including 16 germ cell tumors, eight ...
The purpose of this study is to examine whether recombinant growth factor BMP-2 can replace autologous bone graft in order to stimulating ossification during
Abstract Introduction: Bone transplant can be used to repair bone defects for bone grafts, alograft, autograft and synthetic bonegraft can be mentioned. Autograft is the idea transplant. But due to complication and limitation in rate of bone and difficulty providing alograft, using synthetic bonegraft in repairing bone defects are becoming ...
Background: Subchondral bone necrosis is important in osteonecrosis, Mb Kienboeck, intraarticular fractures or osteochondral grafting. As revascularization follows, bone resorption may lead to collapse in load bearing areas during the remodeling. Bisphosphonates are potent osteoclast inhibitors. Our hypothesis was that local bisphosphonate treatment of an osteochondral graft, in a high load environment, would protect the subchondral bone from collapse and maintain the joint architecture during remodeling. To investigate this, we used a rat bone chamber model to subject a necrotic osteochondral graft to a large mechanical load during remodeling. Method: Cylindrical osteochondral grafts were taken from the patellar groove of rats, one end of the cylinder being the joint surface. The grafts were frozen, thawed and treated with alendronate. The length of the cylinder was measured and the grafts were placed in the chambers, which were inserted into the proximal tibia of rats. The chambers were left ...
Synonyms for bone chips in Free Thesaurus. Antonyms for bone chips. 16 synonyms for bone: cram, grind, os, osseous tissue, off-white, pearl, ivory, bone up, grind away, mug up, swot, swot up, cram, drum, get up, debone. What are synonyms for bone chips?
A method by which immune responses to cortical bone grafts and other substrates (e.g., cement, IPN, etc.) can be minimized and at the same time graft osteoinductive potential can be improved, and improved graft substrate materials are disclosed. The method of the invention provides new types of bone grafts that incorporate into host bone more thoroughly and more rapidly, eliminating long-term complications, such as fracture, non-union, infection, and rejection. In the method of the invention, bone grafts or other substrates are modified to have an osteoinductive surface modification that the recipients body will accept as its own tissue type and therefore will not reject or otherwise cause to fail. The osteoinductive surface modification comprises a biopolymer matrix coating that is seeded with periosteal cells that have been previously harvested either from the graft recipient or from an allogenic or xenogenic donor source.
The present invention is directed to a process for cleaning large bone grafts using a pressure mediated flow of solutions, and to the bone grafts produced thereby where the bone grafts are suitable for transplantation into a human. The present method includes inducing a positive and/or negative pressure-mediated flow of solvent through an opening in the bone shaft of the large bone graft thereby removing bone marrow elements, as well as any bacteria particles and/or virus particles present. The bone grafts produced are suitable for transplantation into a human and are essentially free from viral and bacterial contamination, for example, free from HIV infectious particles.
The most recently funded projects span a broad range of topics and scientific areas, including development of a reparative patch for herniated discs, a software-based analysis process to generate a velocity map of atrial fibrillation, an improved cell production system for cancer immunotherapy, a storage and transportation device for fresh osteochondral allografts, novel methods for allograft bending and engineering allografts for knee repair, and software for analyzing core infarct volume in strokes ...
Complex skeletal injuries and large bone fractures are still a significant clinical problem in US. Approximately 1.5 million Americans (veterans, their families, and civilians) every year suffer from bone loss due to traumatic skeletal injuries, infection, and resection of primary tumors that require extensive grafting to bridge the gap. The US bone graft market is over $2.2 billion a year. Due to insufficient mechanical stability, lack of vascularity, and inadequate resorption of the graft, patients with traumatic large skeletal injuries undergo multiple costly operations followed by extensive recovery steps to maintain proper bone alignment and length. Current strategies for repairing damaged or diseased bones include autologous or allograft bone transplantations. However, limited availability of autografts and risk of disease transmission associated with allografts have necessitated the search for the development of new bone graft options and strategies. The overall goal of this project is to develop
In this study, we aimed at developing and validating a technique for the engineering of osteochondral grafts based on the biological bonding of a chondral layer with a bony scaffold by cell-laid extracellular matrix. Osteochondral composites were generated by combining collagen-based matrices (Chondro-Gide) containing human chondrocytes with devitalized spongiosa cylinders (Tutobone) using a fibrin gel (Tisseel). We demonstrate that separate pre-culture of the chondral layer for 3 days prior to the generation of the composite allows for (i) more efficient cartilaginous matrix accumulation than no pre-culture, as assessed histologically and biochemically, and (ii) superior biological bonding to the bony scaffold than 14 days of pre-culture, as assessed using a peel-off mechanical test, developed to measure integration of bilayered materials. The presence of the bony scaffold induced an upregulation in the infiltrated cells of the osteoblast-related gene bone sialoprotein, indicative of the ...
Osteoarticular allografts represent a reconstructive option after bone tumor resection around the knee in growing children. The major advantage is the chance to preserve the growth plate of the remaining bone, but the disadvantage is the high failure rate eventually requiring definitive prosthetic replacement at skeletal maturity. We retrospectively reviewed 22 patients who underwent osteoarticular allograft reconstructions of the distal femur (16) or proximal tibia (6). There were 12 females and 10 males with an average age at surgery of 11 years (7-15). The diagnosis was osteosarcoma in 19 cases and Ewing sarcoma in 3. All patients underwent pre- and post-operative chemotherapy. At an average follow-up of 103 months (12-167), 18 patients (82%) were alive and 4 had died (18%). We observed 10 allograft failures requiring prosthetic replacement, 6 in distal femur and 4 in proximal tibia reconstructions. At last follow-up 8 allografts (36%) were still in place. Overall allograft survival was 79.6% ...
... Bone grafts are used to fill in a defect where the bone is missing around the teeth or where bone is needed for implants. The
Do you need a bone grafting procedure? Schedule a consultation at Oramax in Schaumburg, IL to learn more about this oral surgery.
Authors: Lewandrowski, Kai‐Uwe , Bondre, Shrikar P. , Gresser, Joseph D. , Wise, Donald L. , Tomford, William W. , Trantolo, Debra J. Article Type: Research Article Abstract: Alteration of the geometrical surface configuration of cortical bone allografts may improve incorporation into host bone. A porous biodegradable coating that would maintain immediate structural recovery and subsequently allow normal graft healing and remodeling by promoting bony ingrowth could provide an osteoconductive surface scaffold. We investigated the feasibility of augmenting cortical bone grafts with osteoconductive biodegradable polymeric scaffold coatings. Three types of bone grafts were prepared: Type I - cortical bone without coating (control), Type II - cortical bone coated with PLGA‐foam, Type III - cortical bone coated with PPF‐foam. The grafts were implanted into the rat tibial metaphysis (16 …animals for each type of bone graft). Post‐operatively the animals were sacrificed at 2 weeks and 4 weeks ...
WESTMINSTER, Colo.--(BUSINESS WIRE)--Mar 4, 2013--Cerapedics, Inc. (Westminster, CO), a medical device company pioneering the use of peptide enhanced bone grafting materials in spine, trauma and orthopedic surgery, is pleased to announce it has surpassed another significant milestone with more than 10,000 patients treated with i-FACTOR™ Peptide Enhanced Bone Graft since the product became available outside the United States in late 2008.. Steve McAdoo, Vice President of Marketing at Cerapedics, stated, "This is a significant achievement and milestone for the company and confirms that i-FACTOR bone graft can provide a viable treatment option to both surgeons and patients looking for an alternative to either autograft harvesting or expensive growth factor technologies." i-FACTOR Peptide Enhanced Bone Graft incorporates Cerapedics proprietary anorganic bone mineral (ABM) and synthetic small peptide (P-15™) technologies for use in a wide variety of spine, trauma and orthopedic surgical ...
Massive bone allografts have been used for limb salvage of bone tumor resections as an alternative to endoprostheses, although they have different outcomes and risks. There is no general consensus about when to use these alternatives, but when it is possible to save the native joints after the resection of a long bone tumor, intercalary allografts offer some advantages despite complications, such as fracture. The management and outcomes of this complication deserve more study.. ...
BONUS BIOGROUP (TASE: BONS) is a biotechnology company applying proprietary, innovative technology to supply tissue-engineered viable bone grafts. The company strives to become a world leader in the field of tissue engineering and live bone transplantation.
With all possible programs taken into account, Augment signifies an enormously profitable prospect for the biotech organization. In the United States, whole bone grafting methods are a $four billion once-a-year market. Increase could largely replace these with a superior merchandise and method. Existing costs of harvesting autogenous bone grafts range from $1100 to $2500 for every method. Of course, this does not take into account expenses relating to discomfort management at the donor site and the prospective for important difficulties. Considering that Increase eliminates the want for harvesting donor bone, these aspects are eliminated ...
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Cardiovascular disease remains the leading cause of mortality among adults in the US. As a result, nearly 600,000 coronary and peripheral vascular bypass graft surgeries are performed in the US each year. To overcome limitations of current gold-standard auto-grafting and synthetic grafting methods, Sharklet Technologies, Inc. (STI) proposes a tissue engineered vascular graft comprised of a Sharklet micropatterned acellular extracellular matrix to enhance graft incorporation via guided endothelial cell migration onto the graft lumen.. ...
Revision TKA with structural bulk allografting is associated with an up to 20% complication rate, usually related directly or indirectly to the allograft itself.10 For this reason endoprostheses are favoured by some authors.. Osteo-articular allografts. Historically in the 1970s there was a surge of interest in the use of bulk osteo-articular allografts. The benefit of osteo-articular grafting is joint preservation and soft tissue reattachment. However high complication rates were reported, particularly infection, fracture, non-union, graft dissolution and joint instability.11,12 Donor grafts need to be carefully matched to the recipient articular surface.The articular cartilage undergoes preservation in dimethyl sulfoxide and is stored at -80°C which results in very few of the chondrocytes remaining viable. This technique is seldom utilised today because of medium- and long-term failure. Hornicek et al reported that 25% of osteo-chondral allografts required surgical intervention due to ...
Fosse, Lars; Muller, Sebastien; Rønningen, Helge; Irgens, Fridtjov; Benum, Pål. (2006) Viscoelastic modelling of impacted morsellised bone accurately describes unloading behaviour: An experimental study of stiffness moduli and recoil properties. Journal of Biomechanics. vol. 39. ...
The company has just received approval to transplant in vitro-developed bone implant into humans & will perform the first bone transplant in the coming week.This pioneering technology grows & regenerates 3D high-density bone graft from fat cells.
Production, means the output of Bone Graft Revenue, means the sales value of Bone Graft This report studies Bone Graft in Global market, especially in North America, China, Europe, Southeast Asia, Japan and India, with production, revenue, consumption, import and export in these regions, from 2011 to 2015, and forecast to 2021. This report focuses on top manufacturers in global market, with prod
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From meniscus transplantation, osteochondral allograft transplantation, multi-ligament knee reconstruction, and biologic injection therapies were here to help relieve your joint pain.
Although not specifically testing peripheral or aperture fixation, Milano and colleagues 16 tested fixation that relied on cancellous versus corticocancellous fixation. The main disadvantage of an IIR filter is that signals may be distorted in an undesirable way.
Infuse Bone Graft - Medtronic Incs spine business is still suffering as a result of all of the controversy surrounding its Infuse Bone Graft product.
Bone grafting teeth in Grass Valley, The Dental Wellness of Grass Valley team will serve your health much better than corrective surgical grafts.
WESTMINSTER, Colo., March 6, 2019 /PRNewswire/ --Cerapedics, a privately-held orthobiologics company, today announced that the International
I recently had a bone graft procedure (2 upper posterior premolars). Right after the surgery I have been told that everything looked perfect. However, after +24 hours I started to experience unberea...
Good news, my surgeon got back to me. The bone graft will not be structural, more just filling up the cracks so recovery wont be AS bad. Thank god! In...
Orthogen LLC is developing and marketing a new line of completely restorable synthetic bone graft products. Visit our website for more information!
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Background & Objective : The preferred Selection of the anterior cervical discectomy alone, with iliac crest bone graft fusion and using the PEEK cage is still in controversial in degenerative disc disease. The aim of this study is comparing them on radiographic and clinical results. Materials & Methods: The all consecutive patients ...
No. of Report Pages: 126. Price (Single User Licence): $ 2900. Purchase the Synthetic Dental Bone Graft Substitute Market Report at: https://www.absolutereports.com/purchase/10555586 Several important topics included in the Synthetic Dental Bone Graft Substitute Industry research report are as follows:. • Overview of Synthetic Dental Bone Graft Substitute Industry. • Market Size (Value and Volume) analysis of Synthetic Dental Bone Graft Substitute Industry. • Synthetic Dental Bone Graft Substitute Industry Competition by Manufacturers, Type and Application. • Synthetic Dental Bone Graft Substitute Industry Major Regions Volume, Value and Sales Price Analysis. • Synthetic Dental Bone Graft Substitute Industry Technology and Development Trend. • Research Findings and Conclusion of Synthetic Dental Bone Graft Substitute Industry. To sum it up, the report concludes with an all-inclusive research result on the industry chain of Synthetic Dental Bone Graft Substitute Industry facilitating ...
Abstract:. Ask for Free Sample @ WMR- https://westernmarketresearch.com/sample-report/1043637/Europe Bone Graft Substitute for Spinal #sample. The Europe Bone Graft Substitute for Spinal Fusion market size is $XX million USD in 2018 with XX CAGR from 2014 to 2018, and it is expected to reach $XX million USD by the end of 2024 with a CAGR of XX% from 2019 to 2024.. Ask for Free Sample-Inquiry and Discount @WMR-https://westernmarketresearch.com/market-report/1043637/Europe Bone Graft Substitute for Spinal #inquiry. This report is an essential reference for who looks for detailed information on Europe Bone Graft Substitute for Spinal Fusion market. The report covers data on Europe markets including historical and future trends for supply, market size, prices, trading, competition and value chain as well as Europe major vendors°Ø information. In addition to the data part, the report also provides overview of Bone Graft Substitute for Spinal Fusion market, including classification, application, ...
Bone graft substitutes are now commonly used in orthopaedic surgery as an alternative to autogenous bone graft. This short review will focus on applications of bone graft substitutes in sports medicine, trauma and spine surgery.. Sports medicine. There is a relative paucity of literature supporting the use of bone graft substitutes in sports medicine compared with trauma or spinal surgery. One of the most common bone grafting indications in sports medicine is opening wedge tibial osteotomy. When compared alongside autogenous iliac crest bone graft (AICBG), union of tibial osteotomy took longer and pain persisted longer when ceramic wedges were used. At six months post-operatively, there was no difference between the two groups in terms of union and outcome.1 Recently, the use of bone grafting in osteotomy has been questioned in a study that showed no difference in complications, union time and rate in grafted and non-grafted osteotomies.2 It is currently unclear whether there is a need to graft ...
Hi... For those of you who have pain from the site where bone was taken for your spinal fusion, please let me know how that pain manifests itself. Is the pain always there? Does it hurt no matter whether youre sitting, standing, walking, etc? Does it hurt when you push on the site? If your surgery was more than a few years ago, has the pain changed at all over the years since your surgery? Thanks. Regards, Linda
Twenty-eight patients with displaced femoral neck fractures were operated on with multiple pinning combined with cancellous bone grafting from the ipsilate