This study explored food allergy caused by eating silkworm (Bombyx mori L.) pupae, a traditionally accepted food and animal feed in East and Southeast Asia, and identified two new allergens by proteomic and immunological methods. Proteins isolated from silkworm pupae were separated by...
Four mulberry silkworm races viz., Pure Mysore, Nistari, NB4D2 & CSR2 and two hybrid (Pure Mysore × CSR2 and Nistari × NB4D2 ) silkworms were selected for the present study. The specific activity of amylase in the haemolymph as well as midgut tissue was estimated. The qualitative analysis of amylase was carried out by Native-PAGE. The commercial characters viz., fecundity, larval weight, larval duration, cocoon weight, shell weight, shell ratio, filament length, denier and renditta were selected. The results of quantitative analysis were subjected for statistical analysis against selected commercial characters to know the level and kind of correlation between them. The results of statistical analysis clearly showed that haemolymph amylase has highly positive correlation with selected commercial characters except larval duration. In contrast, the midgut amylase indicated highly positive correlation with larval duration only. The zymograms of amylase also exhibited variation among the selected ...
A baculovirus, named BomaNPV S2, was isolated from a diseased larva of the wild silkworm, Bombyx mandarina. Notably, BomaNPV S2 exhibited a distinguishing feature in that its host range covered that of both Bombyx mori nucleopolyhedrosis virus (BmNPV) and Autographa californica multiple nucleopolyhedrovirus (AcMNPV) in cultured cells. It could replicate in cells of B. mori (Bm5 and BmN), Spodoptera frugiperda (Sf9) and Trichoplusia ni (Tn-5B1-4). However, occlusion-derived virions of BomaNPV S2 in B. mori cells contained only a single nucleocapsid, whereas they contained multiple nucleocapsids in Tn-5B1-4 cells. The complete genome sequence of BomaNPV S2, including predicted ORFs, was determined and compared with the genome sequence of its close relatives. The comparison results showed that most of the BomaNPV S2 genome sequence was shared with BmNPV (BmNPV T3) or BomaNPV S1, but several regions seemed more similar to regions of AcMNPV. This observation might explain why BomaNPV S2 covers the host
Gopinathan, KP (2012) Welcome to the world of insects! In: CURRENT SCIENCE, 102 (11). p. 1503. Gopinathan, KP (2008) T. Ramakrishnan (1922-2008). In: Current Science, 94 (7). pp. 935-936. Singh, Amit and Singh, Madhuri Kango and Parthasarathy, R and Gopinathan, KP (2007) Larval legs of mulberry silkworm Bombyx mori are prototypes for the adult legs. In: Genesis, 45 (4). pp. 169-176. Dhawan, Sangeeta and Gopinathan, KP (2005) Phylogeny of the Insect Homeobox Gene (Hox) Cluster. In: Genomics Proteomics Bioinformatics, 3 (1). pp. 42-46. Dhawan, Sangeeta and Gopinathan, KP (2004) Molecular cloning and expression pattern of an armadillo homologue from the mulberry silkworm Bombyx mori. In: Gene Expression Patterns, 4 (1). pp. 15-23. Dhawan, Sangeeta and Gopinathan, KP (2003) Expression profiling of homeobox genes in silk gland development in the mulberry silkworm Bombyx mori. In: Development Genes and Evolution, 213 (11). pp. 523-533. Dhawan, Sangeeta and Gopinathan, KP (2003) Cell cycle events ...
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1. The action of the diapause hormone has been studied by injecting extracts of the heads of male moths or of the brain-suboesophageal ganglion complexes of pupae into pupae expected to produce non-diapause eggs.. 2. The effect of the injection of hormone upon young oocytes is to make them develop into diapause eggs. Older oocytes, which have already acquired non-diapause characters, are not affected.. 3. The hormone is almost completely inactivated when injected on the day of pupation. The hormone is most effective when injected into pupae 2-3 days old, at which stage the ovarioles have started to grow vigorously. It is ineffective 1-2 days before adult emergence, by which time all the oocytes have acquired non-diapause characters.. 4. The hormone is inactivated in all pupae irrespective of whether they are destined to produce diapause eggs or non-diapause eggs. Inactivation of diapause hormone (in contrast to that of juvenile hormone) is partially relieved by exposure to low temperature or by ...
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Prolyl 4-hydroxylase (P4H) is a heterotetramer enzyme consisting of alpha-subunits (P4Halpha) and beta-subunits (P4Hbeta), and is required for collagen biosynthesis. Previously, we generated transgenic silkworms that produced human type III collagen fragments (mini-collagens) in the posterior silk gland (PSG). However, prolyl 4-hydroxylation did not occur on the mini-collagens, because in spite of an abundant expression of P4Hbeta in PSGs, P4Halpha expression was quite low there, thus resulting in an insufficient activity of P4H. In this study we aimed at generating hybrid transgenic silkworms whose PSGs are capable of producing mini-collagens and enough P4H for their prolyl 4-hydroxylation. Isolated PSGs were bombarded with fibroin L-chain gene promoter-driven vectors containing Bombyx mori P4Halpha (BmP4Halpha) cDNAs and were transplanted into the hemolymphatic cavity. The P4H activity in the PSG cells significantly increased, indicating that the expressed BmP4Halpha formed active tetramers with
LOCUS DF090445 668521 bp DNA linear CON 26-OCT-2017 DEFINITION Bombyx mori DNA, scaffold: Bm_scaf130, strain: p50T/Dazao. ACCESSION DF090445 BABH01000000 VERSION DF090445.1 DBLINK BioProject:PRJDA20217 BioSample:SAMD00036537 KEYWORDS WGS. SOURCE Bombyx mori (domestic silkworm) ORGANISM Bombyx mori Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Lepidoptera; Glossata; Ditrysia; Bombycoidea; Bombycidae; Bombycinae; Bombyx. REFERENCE 1 (bases 1 to 668521) AUTHORS Mita,K. and Xia,Q. CONSRTM The international silkworm genome sequencing consortium TITLE Direct Submission JOURNAL Submitted (06-SEP-2007) to the DDBJ/EMBL/GenBank databases. Contact:Kazuei Mita National Institute of Agrobiological Sciences, Insect Genome Research Unit; 1-2 Owashi, Tsukuba, Ibaraki 305-8634, Japan REFERENCE 2 AUTHORS CONSRTM The International Silkworm Genome Consortium TITLE The genome of a lepidopteran model insect, the silkworm Bombyx mori JOURNAL Insect Biochem. Mol. ...
LOCUS DF090416 1310704 bp DNA linear CON 26-OCT-2017 DEFINITION Bombyx mori DNA, scaffold: Bm_scaf101, strain: p50T/Dazao. ACCESSION DF090416 BABH01000000 VERSION DF090416.1 DBLINK BioProject:PRJDA20217 BioSample:SAMD00036537 KEYWORDS WGS. SOURCE Bombyx mori (domestic silkworm) ORGANISM Bombyx mori Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Lepidoptera; Glossata; Ditrysia; Bombycoidea; Bombycidae; Bombycinae; Bombyx. REFERENCE 1 (bases 1 to 1310704) AUTHORS Mita,K. and Xia,Q. CONSRTM The international silkworm genome sequencing consortium TITLE Direct Submission JOURNAL Submitted (06-SEP-2007) to the DDBJ/EMBL/GenBank databases. Contact:Kazuei Mita National Institute of Agrobiological Sciences, Insect Genome Research Unit; 1-2 Owashi, Tsukuba, Ibaraki 305-8634, Japan REFERENCE 2 AUTHORS CONSRTM The International Silkworm Genome Consortium TITLE The genome of a lepidopteran model insect, the silkworm Bombyx mori JOURNAL Insect Biochem. Mol. ...
Effects of KK-42, an imidazole derivative, on rearing and reproductive performance of Bombyx mori L. during the hot, wet season - Volume 19 Issue 1 - Kamalendu Banerjee, Debes Chandra Deb
TY - JOUR. T1 - Sequences of two cDNAs encoding silkworm homologues of Drosophila melanogaster squid gene. AU - Li, Feng Qian. AU - Sun, Guan Cheng. AU - Ueda, Hitoshi. AU - Hirose, Susumu. PY - 1995. Y1 - 1995. N2 - The squid (sqd) gene of Drosophila melanogaster encodes a few isoforms of a heterogeneous nuclear (hn) RNA-binding protein. We isolated two types of cDNAs coding for homologues of the Sqd protein from the silkworm Bombyx mori. The two predicted amino acid (aa) sequences are identical up to aa 280 and then diverge. The silkworm and fruit fly proteins share 80% homology in the RNA-binding motif region. These cDNAs detect 2.0-, 1.8- and 1-kb mRNAs in the middle and posterior silk glands.. AB - The squid (sqd) gene of Drosophila melanogaster encodes a few isoforms of a heterogeneous nuclear (hn) RNA-binding protein. We isolated two types of cDNAs coding for homologues of the Sqd protein from the silkworm Bombyx mori. The two predicted amino acid (aa) sequences are identical up to aa 280 ...
Transgenic techniques offer a valuable tool for determining gene functions. Although various promoters are available for use in gene overexpression, gene knockdown, and identification of transgenic individuals, there is nevertheless a lack of versatile promoters for such studies, and this dearth acts as a bottleneck, especially with regard to nonmodel organisms. Here, we succeeded in identifying a novel strong and ubiquitous promoter/enhancer in the silkworm. We identified a unique silkworm strain whose reporter gene showed strong and ubiquitous expression during the establishment of enhancer trap strains. In this strain, the transposon was inserted into the 5′UTR of hsp90, a housekeeping gene that is abundantly expressed in a range of tissues. To determine whether the promoter/enhancer of hsp90 could be used to induce strong gene expression, a 2.9-kb upstream genomic fragment of hsp90 was isolated (hsp90P2.9k), and its transcriptional activation activity was examined. Strikingly, hsp90P2.9k ...
1BOM: Three-dimensional solution structure of bombyxin-II an insulin-like peptide of the silkmoth Bombyx mori: structural comparison with insulin and relaxin.
TY - JOUR. T1 - Allergenic characterization of 27-kDa glycoprotein, a novel heat stable allergen, from the pupa of silkworm, Bombyx mori. AU - Jeong, Kyoung Yong. AU - Son, Mina. AU - Lee, June Yong. AU - Park, Kyung Hee. AU - Lee, Jae Hyun. AU - Park, Jung Won. PY - 2016/1/1. Y1 - 2016/1/1. N2 - Boiled silkworm pupa is a traditional food in Asia, and patients with silkworm pupa food allergy are common in these regions. Still now only one allergen from silkworm, arginine kinase, has been identified. The purpose of this study was to identify novel food allergens in silkworm pupa by analyzing a protein extract after heat treatment. Heat treated extracts were examined by proteomic analysis. A 27-kDa glycoprotein was identified, expressed in Escherichia coli, and purified. IgE reactivity of the recombinant protein was investigated by ELISA. High molecular weight proteins (above 100 kDa) elicited increased IgE binding after heat treatment compared to that before heat treatment. The molecular ...
3UST: Crystal structure of Bombyx mori nucleopolyhedrovirus ORF75 reveals a pseudo-dimer of thiol oxidase domains with a putative substrate-binding pocket
Serratiopeptidase (Serratia E-15 protease, also known as serralysin, serrapeptase, serratiapeptase, serratia peptidase, serratio peptidase, or serrapeptidase) is a proteolytic enzyme (protease) produced by enterobacterium Serratia sp. E-15. This microorganism was originally isolated in the late 1960s from silkworm Bombyx mori L. (intestine), Serratiopeptidase is present in the silkworm intestine and allows the emerging moth to dissolve its cocoon. Serratiopeptase is produced by purification from culture of Serratia E-15 bacteria. Some alternative medicine proponents claim that serratiopeptidase is beneficial for pain and inflammation but "existing trials [have been] small and generally of poor methodological quality." Online medical journal Bandolier (specializing in evidence-based thinking about healthcare) published an article (in about 2001) in response to a readers enquiry about serratiopeptidase. After searching PubMed and the Cochrane Library "to see if there are any randomised, ...
Bombyx mori. For hatching silkworms. Life cycle takes about 6 to 8 weeks after eggs hatch. Silkworms require fresh mulberry leaves or item #143966 Silkworm Artificial Dry Diet (not included). With instructions.
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Background: The silkworm, Bombyx mori, is one of the most economically important insects in many developing countries owing to its large-scale cultivation for silk production. With the development of genomic and biotechnological tools, B. mori has also become an important bioreactor for production of various recombinant proteins of biomedical interest. In 2004, two genome sequencing projects for B. mori were reported independently by Chinese and Japanese teams; however, the datasets were insufficient for building long genomic scaffolds which are essential for unambiguous annotation of the genome. Now, both the datasets have been merged and assembled through a joint collaboration between the two groups. Description: Integration of the two data sets of silkworm whole-genome-shotgun sequencing by the Japanese and Chinese groups together with newly obtained fosmid- and BAC-end sequences produced the best continuity (~3.7 Mb in N50 scaffold size) among the sequenced insect genomes and provided a high degree
Three structurally related and novel antibacterial peptides have been isolated from the haemolymph of the silkworm, Bombyx mori, immunized with Escherichia coli. These peptides were 32 amino acids long and characteristically rich in proline residues. A unique threonine residue in each peptide was O-glycosylated and the modification seemed to be important for expression of antibacterial activity. The primary structure and antibacterial character of the novel peptides resemble those of abaecin (41% identity in amino acid sequence), an antibacterial peptide of the honeybee, although abaecin is not O-glycosylated. Incubation of the novel peptides with a liposome preparation caused leakage of entrapped glucose under low-ionic-strength conditions, suggesting that a target of the peptides is the bacterial membrane. We propose the name lebocin for the novel peptide family isolated from B. mori. ...
Sackton, T.B. and Corbett-Detig, R.B. and Nagaraju, J. and Vaishna, L. and Arunkumar, K.P. and Hartl, D.L.. (2014) Positive selection drives faster-Z evolution in silkmoths. Evolution, 68 (8). pp. 2331-2342. ISSN 0014-3820 Sah, N.K. and Taneja, T.K. and Pathak, Niteen and Begum, R. and Athar, M. and Hasnain, S.E. (1999) The baculovirus antiapoptotic p35 gene also functions via an oxidant-dependent pathway. Proceedings of the National Academy of Sciences, 96 (9). pp. 4838-4843. ISSN 0027-8424 Sharma, A. and Niphadkar, M.P. and Kathirvel, P. and Nagaraju, J. and Singh, Lalji (1999) Brief communication. DNA fingerprint variability within and among the silkworm Bombyx mori varieties and estimation of their genetic relatedness using Bkm-derived probe. Journal of Heredity, 90 (2). pp. 315-319. ISSN 1471-8505 Sharma, G. and Upadhyay, S. and Srilalitha, M. and Nandicoori, V.K. and Khosla, Sanjeev (2015) The interaction of mycobacterial protein Rv2966c with host chromatin is mediated through non-CpG ...
Bombyx mori L.. K M Ponnuvel*, K Ashok Kumar, D Velu, P Somasundaram, R K Sinha and C K Kamble. Biotechnology Laboratory, Central Sericulture Germplasm Resources Centre, Thally Road, Hosur 635 109, India. Received 12 May 2006; revised 18 June 2007; accepted 6 October 2007. N-terminal amino acid sequence of esterase gene was blast searched with Bombyx mori EST (expressed sequence tag) database. EST clone fbpv0006 showed 95% homology with N-terminal sequence of esterase protein. Further, the genomic organization of exons and introns were identified using the EST clone sequence. The results on genomic organization of esterase gene indicated that the blood esterase gene possesses two exons with varying length of 192 and 524 bp, and a long intron of 2124 bp length present between these two exons. The primers were designed to the intron and exon regions and the fragments were PCR amplified using genomic DNA from silk moth as template. The amplicon showed a mol wt 799 bp in the intron region and 547 bp ...
Author Summary The number of larval instars in insects varies greatly across insect taxa and can even vary at the intraspecific level. However, little is known about how the number of larval instars is fixed in each species or modified by the environment. The silkworm, Bombyx mori, provides a unique bioresource for investigating this question, as there are several
Silk is a non-absorbable braided surgical suture composed of an organic protein called fibroin. The protein is derived from the domesticated species Bombyx mori (B mori) of the family Bombycidae. Get a quote today.
Bombyx mori bidensovirus (BmBDV), which belongs to the Bidnaviridae family established by the International Committee on Taxonomy of Viruses in 2011, was the first bidensovirus identified in insects. The structure of BmBDV is similar to that of parvoviruses, while its replication is similar to that of adenoviruses. Although BmBDV has the potential to be used as a tool in biological pest control and as an expression vector, virus rescue has been a bottleneck in the application of this virus. In this study, we constructed a full-length genomic clone of BmBDV and showed that its terminal structure was restored. A recombinant BmBDV that expressed the green fluorescence protein (GFP) gene was constructed. Then, BmN cells, which are an ovarian cell line, were co-transfected with the linearized genome using continuous culture and expanded cell culture methods. The results showed that the GFP gene was expressed successfully, and that cell lesions occurred in virus-infected cells.
diapause hormone: from embryonic stage of Bombyx mori; contains 24-amino acid residues; amino acid sequence given in first source
Read more about Genomic boost to protect Assams muga silkworm on Business Standard. A snapshot of the muga silkworm genome decoded by Indian scientists offers vital clues for imparting disease-resistance to help conserve the economically important insect which spins the distinctive golden yellow fabric synonymous with Assam.
More fun silkworm trivia from Weaving Todays BeWeave It column!. Imagine flowing down the aisle in a darkened room in a silk wedding dress that glows red, orange, and green under a UV light. Scientists in Japan have been experimenting with breeding mutant silkworms that produce silk that glows under a UV light. These silkworms have had genetic material from other organisms inserted into their genomes so they produce a silk with fluorescent qualities. The transgenic critters have a red glowing protein from Discosoma corals, orange from the Fungia concinna coral, or a green fluorescent protein from jellyfish. . . . → Read More: Silkworm Trivia. ...
BOMBYX mori, the domesticated silkworm, is one of the most genetically well-studied insects, with 246 mutations that have been sorted into 27 linkage groups (LGs) (Banno et al. 2005). Genome projects and related work are underway using B. mori as a model organism for Lepidoptera, the most serious group of agricultural pests (for recent review, see Goldsmith et al. 2004). Large-scale sequencing projects of expressed sequence tags (ESTs) (Mita et al. 2003; Cheng et al. 2004) and whole-genome shotgun (WGS) sequences (Mita et al. 2004; Xia et al. 2004) have been performed, and our knowledge of silkworm genes and genome sequence has dramatically increased. However, basic genome research on this insect is still far behind compared with other model organisms such as Drosophila melanogaster, and assignment of fundamental information such as genome sequences, ESTs, BAC contigs, mutant phenotypes, and chromosomal locations on detailed linkage maps is an urgent priority.. Two preliminary molecular linkage ...
1982. Sylvia A. Johnson. Humans have been raising silkworms for their precious silk for thousands of years. Because of its long association with man, the silkworm moth is actually …
Bombyx mori BMCHIR1protein: is a chitinase-like gene induced by 20-Hydroxyecdysone in Silkworm; amino acid sequence in first source
Despite Hodmandod Minors somewhat nonchalant attitude to sericulture (throwing in a bit of silkworm diet after being nagged on the phone, then ramming down the lid and running away fast) there were surprisingly few silkworm casualties on my return. The night I got back I spent until midnight picking out withered grey corpses, putting them on fresh paper and grating in more food. Altogether there were about six - mostly in the box that was streaming with condensation - but there have been more casualties since. At one stage there seemed to be so many corpses every time I looked that I was thinking that my little colony was suffering from a plague (like the one that afflicted most of Europe in the nineteenth century) and could understand how desperate the sericulturists must have felt as generation after generation of silkworms succumbed no matter what anyone did ...
Many people ask about Cynthia Robinson Height and Weight 2016, size, age, body statistics and measurements. Cynthia Robinson is an American Trumpet player, her
August 1965: John writing to Cynthia during The Beatles American Tour. ...what he said about it. Its not that much bother really, is it? When you think about it - cause Im sure Dot [the Lennons housekeeper] and Lil [Cynthias mother] and Bennigs, Tommy, Jordy, etc. can understand something as simple as us wanting to be alone for a day - I dont mean Julian - I mean dont pack him off to Dots or anywhere - I really miss him as a person now - do you know what I mean, hes not so much The Baby or My Baby anymore, hes a real living part of me now, you know hes Julian and everything and I cant wait to see him, I miss him more then Ive ever done before - I think its been a slow process my feeling like a real father! I hope all this is clear and understandable. I spend hours in dressing rooms and things thinking about the times Ive wasted not being with him - and playing with him - you know I keep thinking of THOSE stupid bastard times when I keep reading bloody newspapers and other ...
Cynthia Thompson is the Business Development Manager for SGP International, a leading developer of departmental data reconciliation and custom designed data management solutions. Thompson can be reached at (212) 685-0819 or at [email protected]
Cynthia Nixons wife was worried about her being bald on their wedding day.The former Sex and the City actress shaved her head for her role as a cancer sufferer in the stage play Wit before her May nuptials to long-term...
Visit Healthgrades for information on Dr. Samia Malik, MD Find Phone & Address information, medical practice history, affiliated hospitals and more.
Samia Hasan has extensive primary care experience having worked as a GP for the past 14 years. The roles presently held by Dr Hasan are c
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Pay attention," the intruder interrupted, and stepped around the desk. "I want you." She slowly raised, then lowered the weapon, and Cynthias head bobbed in perfect rhythm. "Oh... you like my new toy?" the intruder whispered. "Its the very latest in gas-powered automatics. It fires a tiny fl chette loaded with a powerful narcotic, and is quiet as a mild cough. One touch of the needle... and youre out like the proverbial light in less than two seconds." She waved the barrel from side to side, and again, Cynthias head followed. "The only downside... it leaves a nasty bruise." She centered the weapons aim between Cynthias breasts. "You dont want me to have to use this thing, do you?" Cynthia shook her head. "Youre going to do exactly what I tell you to do, arent you?" Cynthia nodded. "Hands behind the chair," she ordered ...
Sigma-Aldrich offers abstracts and full-text articles by [Chun Pan, Yan-Fen Hu, Hua-Shan Yi, Juan Song, La Wang, Min-Hui Pan, Cheng Lu].
Private investigator Cormoran Strike returns in a new mystery from Robert Galbraith, author of the #1 international bestseller The Cuckoos Calling. Read the first two chapters of The Silkworm below, and meet Strikes new client. The Silkworm goes on sale June 19th, but you can preorder your copy today at your local independent bookstore or […]
Did you just roll your eyes?) In all seriousness, a colleagues look of disdain or contempt may seem innocuous. But it absolutely is not.. Eye rolling is just one - among many - uncivil behaviors that may contribute to unhealthy or toxic workplaces. And research has proven that such environments in healthcare can have dangerous consequences for patients, including harm, injury, or even death.. So how does one address such a serious issue? For more than two decades, that question has been the lifes work of Cynthia Clark, PhD, RN, ANEF, FAAN, Strategic Nursing Advisor for ATI Nursing Education.. And, she finally found a solution.. For the past year, Dr. Clark has led a team of instructional designers, psychometricians, and computer programmers to address the issue of civility. Their goal? To create an interactive and engaging learning solution that will give nursing students the skills to:. ...
Visit Healthgrades for information on Dr. Cynthia Hom, MD Find Phone & Address information, medical practice history, affiliated hospitals and more.
Cynthia Nixon and director Lynne Meadow, both cancer survivors, share the challenge and the music of Margaret Edson's Wit on Broadway.
Cynthia Nixon and director Lynne Meadow, both cancer survivors, share the challenge and the music of Margaret Edson's Wit on Broadway.
Laura Linney and Cynthia Nixon swap the two lead female roles in the latest revival of The Little Foxes. Between performances they talk Tony nominations, sexism, and the wisdom of Stockard Channing.
Cynthia Zelis MD is a Family Practitioner who practices in Strongsville, OH. Get a full report about this doctors background by clicking here.