TY - JOUR. T1 - Pseudoprogression of glioblastoma after chemo- and radiation therapy. T2 - Diagnosis by using dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging with ferumoxytol versus gadoteridol and correlation with survival. AU - Gahramanov, Seymur. AU - Muldoon, Leslie. AU - Varallyay, Csanad G.. AU - Li, Xin. AU - Kraemer, Dale. AU - Fu, Rongwei (Rochelle). AU - Hamilton, Bronwyn. AU - Rooney, William. AU - Neuwelt, Edward. PY - 2013/3. Y1 - 2013/3. N2 - Purpose: To compare gadoteridol and ferumoxytol for measurement of relative cerebral blood volume (rCBV) in patients with glioblastoma multiforme (GBM) who showed progressive disease at conventional magnetic resonance (MR) imaging after chemo- and radiation therapy (hereafter, chemoradiotherapy) and to correlate rCBV with survival. Materials and Methods: Informed consent was obtained from all participants before enrollment in one of four institutional review board-approved protocols. Contrast agent leakage maps and rCBV ...
Author: Huber, Laurentius et al.; Genre: Journal Article; Published in Print: 2014; Keywords: Vascular space occupancy; Slab-selective VASO; Cerebral blood volume; 7 Tesla; fMRI acquisition techniques; Title: Slab-selective, BOLD-corrected VASO at 7 Tesla provides measures of cerebral blood volume reactivity with high signal-to-noise ratio
In medicine, intravascular volume status refers to the volume of blood in a patients circulatory system, and is essentially the blood plasma component of the overall volume status of the body, which otherwise includes both intracellular fluid and extracellular fluid. Still, the intravascular component is usually of primary interest, and volume status is sometimes used synonymously with intravascular volume status. It is related to the patients state of hydration, but is not identical to it. For instance, intravascular volume depletion can exist in an adequately hydrated person if there is loss of water into interstitial tissue (e.g. due to hyponatremia or liver failure). Volume contraction of intravascular fluid (blood plasma) is termed hypovolemia, and its signs include, in order of severity: a fast pulse infrequent and low volume urination dry mucous membranes (e.g. a dry tongue) poor capillary refill (e.g. when the patients fingertip is pressed, the skin turns white, but upon release, the ...
Several studies have demonstrated increased rCBV in high-grade gliomas compared with low-grade tumors.2,4-6,8-10 There is, however, considerable variation in the reported rCBV values for low- and high-grade tumors (On-line Table). In SE-EPI DSC imaging, transverse relaxation rates peak at a vessel diameter of 1-2 μm, whereas in GE-EPI DSC imaging they plateau at 3-4 μm and then remain independent of vessel size, explaining the lower rCBVs found with SE techniques.6 Differences may also be due to variations in the histologic types of LGG examined and inclusion or exclusion of intratumoral vessels in the analysis, often not specified.. We demonstrated that inclusion of large intratumoral vessels significantly increases rCBVmax values in all types of LGG. Their identification may be difficult on rCBV color maps alone and necessitates reviewing of unprocessed perfusion data. The diameter of intratumoral vessels clearly identifiable on GE-EPI images lies in the millimeter range (approximating the ...
Synonyms for Blood volume in Free Thesaurus. Antonyms for Blood volume. 76 synonyms for blood: lifeblood, gore, vital fluid, family, relations, birth, descent, extraction, ancestry, lineage, kinship, kindred, hostility, anger.... What are synonyms for Blood volume?
PURPOSE: To use multimodal magnetic resonance imaging (MRI) to quantify treatment-induced changes in the whole volume of diffuse infiltrating pontine gliomas and correlate them with progression-free survival (PFS). METHODS AND MATERIALS: This prospective study included 22 children aged 3.3 to 14.7 years (median, 5.9 years). Multimodal MRI was performed at 3 distinct time points: before treatment, the first week following radiation therapy (RT), and 2 months after RT. The imaging protocol included morphologic, multi b-value diffusion; arterial spin labeling; and dynamic susceptibility contrast-enhanced perfusion. Morphologic and multimodal data-lesion volume, diffusion coefficients, relative cerebral blood flow, and relative cerebral blood volume (rCBV)-were recorded at the 3 aforementioned time points. The Wilcoxon test was used to compare each individual parameter variation between time points, and its correlation with PFS was assessed by the Spearman test. RESULTS: Following RT, the tumors ...
Looking for hypervolemia? Find out information about hypervolemia. See also: Formulas for the Volumes of Some Common Solids Formulas for the Volumes of Some Common Solids Solid Volume1 cube l 3 right rectangular... Explanation of hypervolemia
The |i|Journal of Biomedical Optics|/i| (JBO) publishes peer-reviewed papers on the use of novel optical systems and techniques for improved health care and biomedical research.
PRIMARY OBJECTIVE:. I. To prospectively determine the sensitivity and specificity of dynamic susceptibility contrast (DSC)-MRI parameters in detecting tumor recurrence versus radiation necrosis for brain metastases treated with stereotactic radiosurgery (SRS).. SECONDARY OBJECTIVES:. I. To correlate radiographic diagnoses with pathologic diagnoses when surgical resection is clinically indicated.. II. To correlate baseline relative cerebral blood volume (rCBV) values and other hemodynamic parameters with tumor primary histology.. III. To assess overall survival, local failure, distant brain failure and neurologic death.. OUTLINE:. Participants undergo a diagnostic MRI with and without contrast and treatment planning DSC perfusion MRI series before receiving SRS at 4-6 weeks after SRS, and then every 3 months unless clinically indicated sooner. ...
The human hippocampal formation is characterized by anterior-posterior gradients of cell density, neurochemistry, and hemodynamics. In addition, some functions are associated with specific subfields (subiculum, CA1-4, dentate gyrus) and regions (anterior and posterior). We performed contrast-enhanced, high-resolution T1-weighted 3T steady state (SS) imaging to investigate cerebral blood volume (CBV) gradients of the hippocampal formation. We studied 14 healthy subjects and found significant CBV gradients (anterior , posterior) in the subiculum but not in other hippocampal subfields. Since CBV is a marker of basal metabolism, these results indicate a greater baseline activity in the anterior compared with the posterior subiculum. This gradient might be related to the role of the subiculum as the main outflow station of the hippocampal formation and might have implications for the mechanisms of neuropsychiatric disorders. © 2014 Wiley Periodicals, Inc. ...
These scientific tests looks convinced, and seems fine for all these while. But if you think about it deeply, it might not be the actual story. Lets take the example of RBCC and anemia. Anemia means the total blood volume in someone body is not sufficient. Are you convinced that just a few tenth or hundred CC of blood that a blood test can measure your total blood volume? In brief, blood test assay is taking proportion of certain substance inside a certain volume of blood, which is quantitative measurement. It doesnt sounds logic that we can measure total blood volume inside a body using this kind of quantitative measurement. Let me describe using a real life example. Assume inside a mall there are 1 million people and we do not know. We would like to know the total number of people and we started the survey. If we sample using 100 people, 60 men and 40 women, we may be able to get the proportion of man to woman in the mall, but we will never able to know the total number of people inside the ...
Tumour cells including those lining vascular spaces (asterisks) and those containing mitotic figures (arrows) show positive granular cytoplasmic staining for fa
A lot of people with ME and/or POTS are thought to have low blood volume and that this low blood volume can cause a variety of symptoms. Now, if you...
I remember vaguely that sometime about 1935 there appeared in Tubercle the observations of two experimenters who, having shaved one side of rabbits chests, pai
The cord provides oxygen and other essentials to the baby in the womb and in the first few minutes after the birth, while the babys lungs are inflating and acclimating to breathing air for the first time. Its essential for babys oxygenation that the cord remain intact for a *minimum* of 3 minutes after the birth, according to the World Health Organization. Additionally, since the blood in the placenta and cord are part of the babys total blood volume and designed to be returned to the baby through the cord after the birth, if the cord is clamped and cut prematurely, the baby is deprived of 30-40% of his total blood volume, which means that many babies have low iron levels due to that blood loss. This is a health problem called "anemia," and its measurable for 6 months or more after the birth in babies whose cords were cut too early ...
View Notes - TheUrinarySystemNew_1 from AVS 350L at Cal Poly Pomona. Vasoconstrictors Functions of the Urinary System Maintains Homeostasis a. Blood volume b. Blood concentration of: 1. fluid balance
The main findings of our study are threefold. First, increased PEEP during positive-pressure ventilation with moderate tidal volumes produced an increase in MSFP, which almost completely compensated for the concomitant increase in RAP and did not change RVR. Consequently, cardiac output did not change. When blood volume was altered, MSFP and RAP changed in the same direction, but RAP was less affected. Accordingly, VRdP and cardiac output decreased and increased in parallel with blood volume, but again, RVR did not change.. Second, MSFPinsp_hold overestimated the MSFPRAO in euvolemic conditions, regardless of the PEEP level, whereas in bleeding and hypervolemia, the observed values were very similar.. Third, the inspiratory hold maneuvers shifted the venous return pressure/flow relationship to the right of the reference venous return curve in euvolemic conditions but did not do so in bleeding or hypervolemia.. To explain the shift in the pressure/flow relationship during the inspiratory holds ...
Semantic Scholar extracted view of [Comparative study of circulating blood volume in dogs using T-1824 dye and Cr 51-labelled erythrocytes]. by N. A. Gorbunova
The most important thing to remember when beginning to read Rebel Blood is that it is unequivocally not a zombie story. You might flip th...
The Volume Merge operation flattens the scalar data in a collection of volumes into a single base volume. This is useful for converting many overlapping volumes into one large volume for more efficient rendering. For example, you can stamp hundreds of thousands of volumes into a single volume for faster rendering, and flatten hierarchies into a low-res base. You can also create a Frustum volume that ensures only voxels in your cameras field of view are created.. ...
This eMedTV resource discusses how aliskiren-HCTZ is used for lowering high blood pressure in adults. This page further explains aliskiren-HCTZ uses, including an explanation of how the drug works to reduce blood volume and relax the blood vessels.
Hypervolemia is a condition in which there is too much fluid in the blood. It is also known as fluid overload. Learn more about the causes.
Which volumes or VDBs in the first input to stamp into. If no name attribute is present, there should be a single volume or VDB and is treated as the density target.. If more than one is present, a name attribute should be present. The name is used to compare with the volumes cooked in the third input.. All of the destination must be aligned and of the same time (vdb or volume).. ...
Adjustable Volume Pipettes found in: DiamondPRO™ Adjustable Volume Pipettor, Research Plus Fixed-Volume Pipettes, Pearl™ Adjustable Volume Pipettes,..
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The 2015 Nissan GT-R Nismo holds a lap time of seven minutes and 8.679 seconds around the Nurburgring, which Nissan claims makes it the fastest volume production car around the track.
Volume. Length. 1cm. Length is measured in mm, cm, m or km. Area. 1cm. 1cm. 1cm 2. Area is measured in mm 2 , cm 2 , m 2 or km 2 3cm 8cm Area = length x width Area…
iMedPub is a new approach to scientific publishing. As an open service to scientists, it is driven by researchers for researchers, while serving the interests of the general public. Volume 9, Issue 2, 2013
iMedPub is a new approach to scientific publishing. As an open service to scientists, it is driven by researchers for researchers, while serving the interests of the general public. Volume 6, Issue 5, 2015
iMedPub is a new approach to scientific publishing. As an open service to scientists, it is driven by researchers for researchers, while serving the interests of the general public. Volume 5, Issue 5, 2014
iMedPub is a new approach to scientific publishing. As an open service to scientists, it is driven by researchers for researchers, while serving the interests of the general public. Volume 2, Issue 1, 2006
Technique Volume 88, Issue 7. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Technique Volume 87, Issue 30. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Before you buy Aussie Aussome Volume Non-Aerosol Hairspray, check out 375 Influenster reviews. Amanda W. said This works pretty good as long as you do not...
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D Psirropoulos, Ap Efthimiadis, G Boudonas, I Papadopoulos, G Papadopoulos, D Ekklisiarchos, M Parthenis, T Constantinidis, N Lefkos. ...
1)   mass ,  2)  bounding box ,  3)  all of the above ,  4)  volume
Closing volume〔邦文〕 (現代臨床機能検査--その実際と解釈) -- (呼吸器機能検査--換気・肺胞機能に関する検査) (1979 ...
Multicenter prospective randomized trial to compare heart failure management strategies based on clinical assessment of volume status vs. direct measurement of blood volume with a radioisotope technique. Subjects will be randomly assigned to a standard care strategy with guideline recommended treatment based on serial clinical assessment of blood volume or a measured blood volume strategy with guideline recommended treatment based on serial measured blood volume. All subjects will undergo blood volume measurement procedures, but the testing results will only be returned to the physician in the group assigned to management according to measured blood volume status. Subjects will be blinded to their study treatment assignment status ...
This study investigated whether excision of either the right or left atrial appendage of rats alters their natriuretic response and the release of atrial natriuretic factor during acute blood volume expansion or reduction. These animals were subjected to a thoracotomy and either had their right or left atrial appendages removed or underwent a right or left atrial sham appendectomy for comparative, control purposes. Intrajugular vein, intracarotid artery, and intravesical catheters were installed 3-4 weeks later under sodium pentobarbital anesthesia. Then, when the rats were conscious, blood volume was expanded using blood from donor rats once every 15 minutes in 3 increments of 10% of the calculated total blood volume at a rate of 5 ml/kg/min. Blood and urine samples were collected before volume expansion and at the end of each 15-minute period, with the withdrawn blood being replaced. A maximal fourfold increase in urinary volume, urinary sodium excretion, and plasma atrial natriuretic factor ...
Effects of hemodialysis on extracellular fluid volume distribution, left ventricular volumes, and cardiac output were determined in patients with end-stage renal disease (n = 19). Distribution of extracellular fluid loss from hemodialysis differed widely among patients, so that weight change correlated weakly with contraction of total blood volume (index of determination 29%, p less than 0.05). End-diastolic volume (EDV) decreased from 150 +/- 49 ml (mean +/- SD) to 118 +/- 42 ml, p less than 0.001; stroke volume (SV) decreased from 108 +/- 36 to 86 +/- 33 ml (p less than 0.001) without change in ejection fraction (from 0.73 +/- 0.09 to 0.74 +/- 0.11). A significant correlation was found between total blood volume (TBV) and EDV before (r = 0.66, p less than 0.005) and after dialysis (r = 0.61, p less than 0.001). The correlation between TBV and SV was highly significant before (r = 0.78, p less than 0.001) and after dialysis (r = 0.66, p less than 0.005), but there was no correlation between ...
To test these hypotheses, we studied 37 consecutive POTS patients aged 14-21 yr (median = 17.2 yr, 11 men and 26 women) and 12 healthy volunteers aged 15-21 yr (median = 17.4 yr, 5 men and 7 women).. POTS patients were referred to our center for symptoms of orthostatic intolerance lasting for longer than 6 mo. Orthostatic intolerance was defined by the presence of lightheadedness, fatigue, headache, neurocognitive deficits, palpitations, nausea, blurred vision, abnormal sweating, and a sensation of shortness of breath or heat while upright with no other medical explanation for the symptoms. In all patients, POTS was confirmed on a screening upright-tilt table test at 70°. POTS was diagnosed by symptoms of orthostatic intolerance during the screening tilt test associated with an increase in sinus HR of ,30 beats/min or to a HR of ,120 beats/min during the first 10 min of tilt as defined in the adult literature (20, 29). We used mercury in-Silastic strain-gauge plethysmography to measure supine ...
The hemodynamic effects of hypovolemia and acidosis were studied in 23 patients with cholera. Studies were made before and during fluid replacement and administration of alkali.. The major hemodynamic abnormalities encountered before rehydration can be ascribed to a reduction in circulating blood volume. Hypovolemia was associated with a reduction in cardiac output, blood pressures, and central blood volume. Restoration of blood volume returned these variables toward normal.. The chief effect of acidosis appeared to be a redistribution of blood from the peripheral to the central circulation; consequently, central blood volume, lesser circulation pressures, and cardiac output were relatively well maintained despite hypovolemia. Fluid administration without correction of acidosis favored a disproportionate increase in central blood volume, while reduction in hydrogen ion concentration attending fluid replacement resulted in a more even distribution of the circulating blood volume and reduced the ...
MATERIALS AND METHODS: We retrospectively analyzed DSC-MR imaging of treatment-naïve, pathology-proved glioblastomas (n = 14), primary central nervous system lymphomas (n = 7), metastases (n = 20), and meningiomas (n = 13) using a protocol designed for relative CBV accuracy (a one-quarter-dose preload and single-dose bolus of gadobutrol, TR/TE = 1290/40 ms, flip angle = 60° at 1.5T). Mean percentage signal recovery, relative CBV, and normalized baseline signal intensity were compared within contrast-enhancing lesion volumes. Classification accuracy was determined by receiver operating characteristic analysis. ...
NEW YORK, NY--(Marketwired - Jan 15, 2014) - Daxor Corporation, (NYSE MKT: DXR) The 43rd annual meeting of the Society of Critical Care...
Both ischemic and non-ischemic heart disease can cause disturbances in the myocardial blood volume (MBV), myocardial perfusion and the myocardial extracellular volume fraction (ECV). Recent studies suggest that native myocardial T1 mapping can detect changes in MBV during adenosine stress without the use of contrast agents. Furthermore, native T2 mapping could also potentially be used to quantify changes in myocardial perfusion and/or MBV. Therefore, the aim of this study was to explore the relative contributions of myocardial perfusion, MBV and ECV to native T1 and native T2 at rest and during adenosine stress in normal physiology. Healthy subjects (n = 41, 26 ± 5 years, 51% females) underwent 1.5 T cardiovascular magnetic resonance (CMR) scanning. Quantitative myocardial perfusion [ml/min/g] and MBV [%] maps were computed from first pass perfusion imaging at adenosine stress (140 microg/kg/min infusion) and rest following an intravenous contrast bolus (0.05 mmol/kg, gadobutrol). Native T1 and T2 maps
To the Editor:. I read with great interest the Hypertension Highlights article, "Sympathetic Nervous System and Blood Pressure in Humans."1 I would like to make 2 comments with regard to regulation of sympathetic activity, which relates to the above-mentioned article and may be of interest to your readers. We reported many years ago that sympathetic activity as measured by plasma norepinephrine increased with age.2 Furthermore, we demonstrated that sympathetic activity was inversely related to the blood volume.3 Joyner et al1 demonstrated that muscle nerve sympathetic activity was inversely related to the level of cardiac output in a group of young healthy men. It is well established that cardiac output depends on the level of the blood volume and decreases, for example, in response to volume changes in the standing-up position. It is, therefore, likely that the interrelationship observed between cardiac output and sympathetic activity is at least in part explained by variations in the level of ...
As a general matter of health, optimum blood volume is essential to the proper function of the bodys cardiopulmonary and circulatory systems. Blood is a significant mass within the body, with an average volume for an adult of 51. liters (1); blood typically represents approximately 8% of body mass. For an elite-level endurance athlete, the blood volume may be 30% greater than that of the average adult.. Blood is composed of solid and liquid elements. Plasma, composed of 90% water, is the liquid that transports various types of dissolved particles as well as blood cells. The cells contained the human blood stream are erythrocytes, leukocytes, and platelets. Erythrocytes are the red blood cells that contain hemoglobin, the protein that transports oxygen within the body, as well as carry the waste carbon dioxide produced by the body. Leukocytes are the white blood cells that are responsible for attacking infection and other hostile organisms within the body. There are five different types of white ...
TY - JOUR. T1 - MR perfusion studies of brain for patients with unilateral carotid stenosis or occlusion. T2 - Evaluation of maps of "time to peak" and "percentage of baseline at peak". AU - Teng, Michael Mu Huo. AU - Cheng, Hui Cheng. AU - Kao, Yi Hsuan. AU - Hsu, Li Chi. AU - Yeh, Tzu Chen. AU - Hung, Chung Shiou. AU - Wong, Wen Jang. AU - Hu, Han Hwa. AU - Chiang, Jen Huey. AU - Chang, Cheng Yen. PY - 2001/2/6. Y1 - 2001/2/6. N2 - Maps of "time to peak" (TTP) and "percentage of baseline at peak" (PBP) were compared with maps of conventional brain perfusion parameters, namely, mean transit time (MTT) and relative cerebral blood volume (rCBV). We performed MR perfusion studies in 11 patients. All of them had occlusion or high-grade stenosis of the unilateral carotid artery. Three areas of old infarct, 4 areas of new infarct, and 10 areas of brain without infarct were evaluated specifically. In all these cases, the TTP maps appeared similar to the MTT maps. They showed increases, normal values, ...
Under normal conditions, blood flow in the renal arterial circulation is antegrade and maintained during diastole. When renal arterial vascular resistance increases or compliance lessens, a decrease in renal diastolic blood flow occurs, which is more pronounced than the decrease in the systolic component (11). This action results in an increased RI. Importantly, the Doppler waveform is altered not by vascular resistance alone but by the interaction of vascular resistance and compliance (e.g., large arterial distensibility, pulse pressure). Therefore, aging, atherosclerosis, and stiffening of the large arteries will result in an increased RI (12). This scenario likely explains the significantly lower baseline RI value in the cohort of healthy young subjects compared with HF patients.. Baseline levels of VII were not different between groups. After multivariate analyses, there was a poor but significant correlation between RVSP and baseline VII, but no significant correlation remained between ...