UNLABELLED The erythropoietic capacity for preoperative autologous blood donation (ECPABD) shows marked inter individual variability. This study was performed to evaluate factors useful to predict individual ECPABD from data available before the first donation. The subjects consisted of 74 adult patients who received autologous blood donation, with a mean of 61 +/- 12.8 yr (SD). We classified the patients into four groups using our criteria for evaluating the ECPABD and investigated the relationships among age, disease, pre-platelet count, and the rate of platelet increase. RESULTS (1) Advanced age and the status of disease were not distinctly correlated with low ECPABD. (2) Patients with a high pre-platelet levels had a low ECPABD regardless of the haemoglobin. (3) Patients in which the platelet count increased in accordance with the level of collection exhibited low pre-platelet counts and high ECPABD. CONCLUSION In patients with high pre-platelet levels, we reduced the amount collected,
Behaviorally associated changes in neuroconnectivity following autologous umbilical cord blood infusion in young children with autism spectrum disorder
PURPOSE: This study tested the hypothesis that autologous blood transfusion (ABT) of ~50% of the red blood cells (RBC) from a standard 450-mL phlebotomy would increase mean power in a cycling time trial. In addition, the study investigated whether further ABT of RBC obtained from another 450-mL phlebotomy would increase repeated cycling sprint ability.. METHODS: In a randomized, double-blind, placebo-controlled crossover design (3-month wash-out), nine highly trained male subjects donated two 450-mL blood bags each (BT trial) or were sham phlebotomized (PLA trial). Four weeks later, a 650-kcal time trial (n = 7) was performed 3 d before and 2 h after receiving either ~50% (135 mL) of the RBC or a sham transfusion. On the following day, transfusion of RBC (235 mL) from the second donation or sham transfusion was completed. A 4 × 30-s all-out cycling sprint interspersed by 4 min of recovery was performed 6 d before and 3 d after the second ABT (n = 9).. RESULTS: The mean power was increased in ...
TY - JOUR. T1 - Detection of homologous blood transfusion. AU - Voß, Sven. AU - Thevis, Mario. AU - Schinkothe, T.. AU - Schänzer, Wilhelm. PY - 2007. Y1 - 2007. N2 - The aim of the present study was to improve and validate a flow cytometric method for the detection of homologous blood transfusion in doping control analysis. A panel of eight different primary antibodies and two different phycoerythrin-conjugated secondary antibodies was used for the detection of different blood populations. The flow cytometer used in this study was the BD FACSArray® instrument. Mixed red blood cell populations were prepared from phenotype known donors. Linearity, specificity, recovery, precision, robustness and interday-precision were tested for every primary antibody used in the presented assay. The technique of signal amplification was utilized for an improved separation of antigens with weak or heterozygous expression to improve the interpretation of histograms. The resulting method allowed to clearly ...
Autotransfusion is a process wherein a person receives their own blood for a transfusion, instead of banked allogenic (separate-donor) blood. There are two main kinds of autotransfusion: Blood can be autologously "pre-donated" (termed so despite "donation" not typically referring to giving to ones self) before a surgery, or alternatively, it can be collected during and after the surgery using an intraoperative blood salvage device (such as a Cell Saver or CATS). The latter form of autotransfusion is utilized in surgeries where there is expected a large volume blood loss - e.g. aneurysm, total joint replacement, and spinal surgeries. The first documented use of "self-donated" blood was in 1818, and interest in the practice continued until the Second World War, at which point blood supply became less of an issue due to the increased number of blood donors. Later, interest in the procedure returned with concerns about allogenic (separate-donor) transfusions. Autotransfusion is used in a number of ...
Cognitive function was assessed in English-speaking study participants using one of three different tools depending on the age of the patient at the time of assessment: The Bayley Scales of Infant and Toddler Development, Third Edition (Bayley-III), the Wechsler Intelligence Scale for Children (WISC-IV), and the Wechsler Preschool and Primary Scale of Intelligence (WPPSI-III). Some patients were assessed with different tools at subsequent visits as they aged during the conduct of the trial. There are two versions of the WPPSI-III for two different age ranges: 2 years & 6 months to 3 years & 11 months, and 4 years to 7 years & 3 months. The Full Scale IQ is calculated for both age ranges and provides a continuous score with an average of 100 and a standard deviation of 15. Change from Baseline to Year 1 was evaluated, with positive numbers indicating an increase in cognitive ability, negative numbers indicating a decrease in cognitive ability, and zero indicating no change ...
Cognitive function was assessed in English-speaking study participants using one of three different tools depending on the age of the patient at the time of assessment: The Bayley Scales of Infant and Toddler Development, Third Edition (Bayley-III), the Wechsler Intelligence Scale for Children (WISC-IV), and the Wechsler Preschool and Primary Scale of Intelligence (WPPSI-III). Some patients were assessed with different tools at subsequent visits as they aged during the conduct of the trial. There are two versions of the WPPSI-III for two different age ranges: 2 years & 6 months to 3 years & 11 months, and 4 years to 7 years & 3 months. The Full Scale IQ is calculated for both age ranges and provides a continuous score with an average of 100 and a standard deviation of 15. Change from Baseline to Year 1 was evaluated, with positive numbers indicating an increase in cognitive ability, negative numbers indicating a decrease in cognitive ability, and zero indicating no change ...
[120 Pages Report] Check for Discount on 2015-2025 Global Cardiopulmonary Autotransfusion System Market Research by Type, End-Use and Region (COVID-19 Version) report by 99Strategy. Summary Cardiopulmonary Autotransfusion System is a sophisticated device with an...
The Consensus Document on Alternatives to Allogenic Blood Transfusion (AABT) has been drawn up by a panel of experts from 5 scientific societies. The Seville Consensus Document on Alternatives to Allogenic Blood Transfusion
Preoperative autologous collections are most beneficial to those patients who are undergoing procedures with substantial anticipated blood loss, such as orthopedic joint replacement, vascular surgery, cardiac or thoracic surgery, and radical prostatectomy. Autologous blood is unnecessary for procedures that seldom require transfusion, such as transurethral resection of the prostate, cholecystectomy, herniorrhaphy, vaginal hysterectomy, and uncomplicated obstetric delivery [14]. A hospitals maximal surgical blood order schedule for blood cross-match can provide estimates of transfusion rates for specific procedures; the generally accepted cutoff at which transfusion is unlikely and autologous blood procurement should not be recommended is 10% [15].. Collection of units should be scheduled as far in advance of surgery as possible for liquid blood storage (up to 42 days), to allow compensatory erythropoiesis [5] to correct the induced anemia. If the erythropoietic response to autologous blood ...
When used as the sole source of transfused blood, the principal advantage of autologous blood transfusion is the avoidance of transmission of infectious agents and the avoidance of the purported adverse immunomodulatory effects of allogeneic transfusion. In the 1990s, however, the risks of transfusion-transmitted diseases have been greatly reduced, and estimates of the cost-effectiveness of pre-operative autologous blood donations now vary between 2470 dollars and 3,400,000 dollars per quality-adjusted year of life saved, depending on assumptions about the existence and magnitude of any adverse immunomodulatory effects of allogeneic transfusion. There is a paucity of randomized controlled trials evaluating the clinical outcomes and the cost-effectiveness of autologous transfusion procedures, and this situation is unlikely to change in the near future because of the difficulties in conducting such trials. Read More ...
Autologous Blood Injection (ABI), also known as Autologous Conditioned Plasma (ACP) Injection is a medical procedure popularized circa 2000, whereby a patients blood is injected into an area of the body for the purposes of healing.. ABI is most commonly used to treat degeneration of tendons, which may occur in association with small tears. This disorder of tendons is frequently referred to as "tendinitis" by the public, however is known as tendinosis or tendinopathy in the medical profession. The procedure is usually performed under ultrasound control by a radiologist.[1] The injection of blood contains small cells called platelets, which contain platelet derived growth factor. This substance is thought to promote tendon healing. A variation on the technique is platelet rich plasma (PRP),[2] which is where the whole blood removed from the patient is spun in a centrifuge, separating the cells of the blood. As such a higher concentration of platelets is delivered into the tissue for healing. As ...
The global Autotransfusion Systems Market is poised to reach USD 505 million by 2024. Autotransfusion Products Market Report provides crucial industry insights that will help your business grow.
An autologous blood transfusion system comprising at least two interconnected blood receptacles, the first of which is evacuated and connected to a suction device for aspirating blood. The second receptacle takes blood from the first by overcoming the vacuum in the first with a greater vacuum in the second without interrupting the ability of the suction device to simultaneously aspirate blood. The second receptacle may comprise a transfer bag for reinfusion into the patient or an infusion set may be connected to the second receptacle to permit simultaneous collection of the blood from the patient and infusion of the blood back into the patient. In either case, the second receptacle is selectively exposed to positive pressure to expel the blood from the second receptacle into the transfer bag or patient. The method includes aspirating blood from the patient and collecting blood in the first receptacle. Blood is thereafter transferred to the second receptacle by increasing the vacuum in the second
Article] Journal of Orthopaedic Trauma. 29(8):349-353, August 2015. (Format: HTML, PDF). Objective: To determine if intraoperative autologous transfusion using a Cell Saver (CS) was routinely indicated for open reduction internal fixation (ORIF) of acetabular fractures, and if so, was there a difference between differing surgical approaches.. Design: Retrospective single-center cohort study.. Setting: University Level 1 trauma center.. Patients/Participants: One hundred forty-five consecutive acetabular fractures using intraoperative autologous transfusion, either treated with an anterior ilioinguinal or a posterior-based Kocher-Langenbeck approach, were compared.. Intervention: Use of CS in ORIF acetabular cases.. Main Outcome Measurements: CS utilization and CS blood return for acetabular ORIF. Mean intraoperative blood loss between the 2 approaches.. Results: CS blood was returned in 29 of the 145 total cases [23/65 anterior (ilioinguinal approach) and 6/80 posterior approach ...
The most common autologous donation is the preoperative donation of blood for possible use by the donor during elective surgery. For example, a person might give one unit of blood each week for up to six weeks before surgery,(because blood can be stored in its liquid form for up to 42 days). Patients cannot make autologous donations after 72 hours prior to their surgery so that the body has enough time to replenish its blood volume before the surgical procedure.. A significant amount of iron is removed with each autologous donation. As a result, iron supplements are often prescribed for patients making autologous donations.. Autologous donation is most often employed in surgery on bones, blood vessels, the urinary tract, and the heart, when the likely need for transfusion is high. Autologous blood accounts for nearly 5 percent of all blood donated. Autologous blood donors must be medically stable patients who are free of infection. There is no age limitation and many children and elderly ...
Autologous blood donation - can we bank on it? Occupational exposure to blood among medical students. Risks to health care workers in developing countries
Since the successful perioperative use of rhEPO more than 5 years ago in an animal model, many reports (1) have detailed its use in clinical medicine. The investigation by Biesma and colleagues joins a growing list of studies that support the preoperative clinical use of rhEPO as an adjunct to decrease allogeneic (homologous) red blood cell use (1, 2). Their study is also unique in that it helps to define specific groups of patients who may most benefit from preoperative rhEPO, namely, those autologous blood donors with blood volumes , 5 L. Autologous blood collection services currently allow many patients who are having elective surgery to bank their own blood. As much as 60% of the autologous blood collected in the United States, however, does not get transfused. In the study by Biesma and colleagues, 54% (27 of 50) of the patients in the rhEPO-treated group were not transfused with any red blood cells. The cost to the hospital pharmacy for rhEPO is approximately $10 per 1000 units, which ...
Both of my pre-operative hospital visits are now complete. On the 12th we went to the General Hospital campus for orientation and the Civic Hospital campus for an autologous blood donation (banking my own blood in case a transfusion is needed); today (20th) was my second autologous blood donation. Orientation involved meeting with the anesthetist and the operating room nurses to answer both general and specific questions (in both directions) and get our bearings as to what, where, when, how and why. Thankfully, every lineup was short and we were finished in only 90 minutes, even though four hours were put aside in our schedule based on the advance arrangements.. The day before the surgery we will get the call of the time of day we have to show up, and Im to show up with only the clothes on my back, a spectacles case, and my autologous blood donation cards. My wife can have everything else, but Im not to have anything else on my person.. Regarding my daily medicinal routine, Im to stop taking ...
Autotransfusion of mediastinal shed blood after open heart surgery has become a common and accepted procedure in reducing the need for homologous transfusion during the last 15 years. The objectives of the present study were to investigate the oxygen
Total joint replacement surgery such as total hip arthroplasty (THA) and total knee arthroplasty (TKA) is associated with intra- and postoperative blood loss leading to postoperative anemia. This can be subsequently treated with allogeneic blood transfusion [1, 2]. Yet, allogeneic blood transfusions carry the risk of infections and non-infectious transfusion reactions [3]. Therefore, different types of blood saving measures (BSMs) have been developed to reduce blood loss or to increase cell mass to avoid allogeneic transfusions [4].. Many studies on the effectiveness of the frequently used BSMs erythropoietin (EPO) and intra- and postoperative drainage and re-infusion of autologous blood (in short: perioperative blood salvage) in orthopedic surgery have been performed. Reviews and meta-analyses showed that EPO and perioperative blood salvage reduce transfusions. However, the included studies had several limitations such as a retrospective design, small patient numbers and poor methodologically ...
The Cell Saver Elite blood/cell salvage device helps you avoid allogeneic blood transfusions & can sequester platelet-poor and platelet-rich plasma.
CATSmart Continuous Autotransfusion System-Fresenius Kabi https://www.catsmart.us. The CATSmart Continuous Autotransfusion System is the only continuous autotransfusion system working on the principle of the continuous flow centrifuge. CATSmart technology is simple to operate, has high PRC Quality, and is engineered to fit into your OR and the way you work. Ref: 0101 CATSM-01-12/19 ...
A 40-year-old man was admitted with symptomatic pulmonary stenosis in Takayasu arteritis. Computed tomographic pulmonary angiography demonstrated no blood flow in the left lung and a severe narrowing in the right main pulmonary artery (Figure 1). Pulmonary angiography showed reduced perfusion in the right lung (Figure 2A). Balloon pulmonary angioplasty (BPA) was attempted in the right pulmonary artery, but BPA was ceased because the patient had a seizure during balloon dilation. We suspect that the seizure was triggered by transient loss of blood flow in the brain during balloon dilation, which blocked the only pulmonary artery that connected the right heart and the lungs. To maintain pulmonary blood flow during balloon angioplasty, a 6-F long introducer sheath was advanced to the right pulmonary artery and successfully crossed the lesion to deliver blood, which was collected from the patients atria and anticoagulated with heparin before BPA. The blood was then injected using syringes at a ...
An autotransfusion apparatus for collecting salvaged blood includes an upper chamber for collecting blood and a lower chamber for receiving blood from the upper chamber. The upper chamber is subjected to a vacuum to withdraw blood from a patient. Particles and lipids are removed from the collected blood by a particle filter and a lipid separator. A selector valve located between the vacuum port and the lower chamber, and between the lower chamber and a vent, selectively couples lower chamber either to the vacuum source or the vent. The lower chamber receives blood from the upper chamber through a pressure-operated drain valve only when the lower chamber is coupled to the vacuum source. Coupling the lower chamber to the vent while the upper chamber is subjected to the vacuum source causes a pressure differential between the chambers, closing the pressure-operated drain valve. This allows the upper chamber to remain under a vacuum and continuously collect blood while the lower chamber drains blood
I got the letter from my surgeons office, saying it is time to set up my blood donations. I am supposed to donate 3 units, starting 34 days prior to surgery. I am having a difficult time finding a center that does this, close to where I live in PA. Also, I have been quoted fees from $148 per unit, to $500 per unit, for them to draw, process, and ship the blood. I am wondering, do most surgeons ask their pts. to do this? And, for those of you who did, how did you feel afterwards. Normally, a
The result of the model calculations are presented in a table given in the appendix for a range of Hi from 0.30 to 0.50 with ANH performed to minimum hematocrits from 0.30 to 0.15. Given a Hi of 0.40, if the Hm is assumed to be 0.25.then from the equation above the RCM count is still high and ANH is not necessary, if BLs does not exceed 2303 ml, since the hemotocrit will not fall below Hm, although five units of blood must be removed during hemodilution. Under these conditions, to achieve the maximum benefit from the technique if ANH is used, no homologous blood will be required to maintain the Hm if blood loss does not exceed 2940 ml. In such a case ANH can save a maximum of 1.1 packed red blood cell unit equivalent, and homologous blood transfusion is necessary to maintain Hm, even if ANH is used. This model can be used to identify when ANH may be used for a given patient and the degree of ANH necessary to maximize that benefit. For example, if Hi is 0.30 or less it is not possible to save a ...
Being a blood donor means that a person allows his or her blood to be drawn so that it can be used at a later time. Sometimes the blood is used by another person, and sometimes the blood is used by the donor herself. Often when a person is scheduled for surgery and has plenty of advance notice, she has the opportunity to bank some of her own blood. This is called an autologous donation. Autologous blood donations do not need to be screened for things like AIDS or hepatitis because the person cannot contract a disease from herself. If she has the disease, she has the disease. If she doesnt, she wont contract it from her own blood. However, if the blood donation is not autologous, it is carefully screened for all types of potential diseases so that the person receiving it does not contract it from the transfusion. Before donating blood, the donor must fill out an extensive questionaire. If the donor has traveled in certain foreign countries recently (where tropical diseases are common, for ...
Being a blood donor means that a person allows his or her blood to be drawn so that it can be used at a later time. Sometimes the blood is used by another person, and sometimes the blood is used by the donor herself. Often when a person is scheduled for surgery and has plenty of advance notice, she has the opportunity to bank some of her own blood. This is called an autologous donation. Autologous blood donations do not need to be screened for things like AIDS or hepatitis because the person cannot contract a disease from herself. If she has the disease, she has the disease. If she doesnt, she wont contract it from her own blood. However, if the blood donation is not autologous, it is carefully screened for all types of potential diseases so that the person receiving it does not contract it from the transfusion.. Before donating blood, the donor must fill out an extensive questionaire. If the donor has traveled in certain foreign countries recently (where tropical diseases are common, for ...
When an autologous blood product is collected but not transfused, OPPS providers should bill Procedure 86890 (autologous blood or component, collection, processing, and storage; predeposited) or 86891(autologous blood or component, collection, processing, and storage; intra- or postoperative salvage) and the number of units collected but not transfused. Procedure 86890 and 86891 are intended to provide payment for the additional resources needed to provide these services, which are not captured when a blood product HCPCS code is not billed. Because billing 86890 or 86891 is only indicated when autologous blood is collected but not transfused, the OPPS provider should bill 86890 or 86891 on the date when the OPPS provider is certain the blood will not be transfused (i.e., date of a procedure or date of outpatient discharge), rather than on the date of the products collection or receipt from the supplier ...
In cardiac surgical patients it is a complex challenge to find the ideal balance between anticoagulation and hemostasis. Preoperative anemia and perioperative higher transfusion rates are related to increased morbidity and mortality. Patient blood management (PBM) is an evidence based patient specific individualized protocol used in the perioperative setting in order to reduce perioperative bleeding and transfusion rates and to improve patient outcomes.. Read More ...
Durch die klinische Studie konnte die Anwesenheit von Fett im Wundblut bestätigt werden. Die Experimente zeigten deutliche Unterschiede der einzelnen Geräte bei der Fettelimination. Die höchste Fettelimination konnte das Gerät C.A.T.S. ® (99,8 ± 0,2 %) erreichen. Das Gerät Xtra® (87,3 ± 7,4 % mit der 225 ml Glocke und 87,8 ± 0,2 % mit der 175 ml Glocke) schnitt gut ab und erreichte durch zusätzliche Filtration mit 96,7 ±, 2,2 % eine ähnlich gute Fettelimination wie C.A.T.S. ®. Das Gerät Electa® erreichte im Programm Popt eine Fettelimination von 92,8 ± 4,4 % und im Programm Pstd nur 69,2 ±2,5 %. Der Cell Saver 5+ lieferte mit 77,6 ± 9,7 % ähnlich schlechte Fetteliminationswerte, wie in älteren Studien ...
Evidence suggests that local anaesthesia after total knee replacement (TKR) provides better knee function in the postoperative period with less post-operative complications like nausea and vomiting as compared to conventional ways of pain treatment (i.e.opioids). Good clinical results have been obtained with and without the use of indwelling catheters. The Bellovac ABT system; a technique to collect, filter and reinfuse blood and tissue fluid, is also often used in TKR. Bellovac ABT is used as an alternative to allogeneic blood transfusion. A combination of both techniques however, is not common yet. Before routinely combining local anaesthesia with the Bellovac technique we want to quantify the amount of local anaesthetic (if any) in the collected and retranfusable blood and tissue fluid. On the basis of these data the safety of combining local anaesthesia with the retransfusion of blood and tissue fluid will be assessed ...
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Система для реинфузии аутологичной эритроцитарной массы АutoLog собирает и обрабатывает кровь из операционной раны, в результате чего формируется отмытая эритроцитарная масса для последующего введения пациенту ...
A directed (or designated) blood donation is one in which a person donates blood that is reserved (at the time of donation) for the transfusion of a specific patient at a later date. The donor is usually a family member or a close friend that has been chosen by the patients family. Consult your childs health care provider if you are interested in learning more about directed donation. It is recommended that families donate in the childs name versus directed donation, because if directed blood is not needed, it is wasted. Blood must be donated within a month of the surgery. If not used, it will be released. An autologous donation is blood collected from the patient in advance of planned surgery.. ...
donating blood to yourself in advance for surgery. by fred cicetti. q: im a geezer planning to have surgery in a few months. i was wondering if i can donate blood to myself in advance?. a: yes you can. this is called "autologous" blood donation. its done in the weeks before non-emergency surgery. the blood is stored until the operation. autologous donation is most often employed in surgery on bones, blood vessels, the urinary tract and the heart, when the likelihood of transfusion is high.. this form of blood donation is good for the patient, but its beneficial to society, too.. people over the age of 69 require half of all whole blood and red blood cells transfused, according to the national blood data resource center (nbdrc). giving blood to yourself cuts down on the demand for blood.. typically, each donated unit of blood, referred to as whole blood, is separated into multiple components, such as red blood cells, plasma, platelets and antihemophilic factor, for transfusion to individuals ...
Autotransfusion Services is a unique specialty that includes collecting and returning shed blood from the surgical field to significantly reduce or eliminate the need for blood transfusions ...
If you face major surgery in the next few weeks, you may want to give your own blood in advance and -- should you need it -- have it earmarked for you. This is called autologous donation and it has
Soothing dry eyes with a drop of blood: Specialists say new technique can help eyes stay nourished 26 August 2017 http://www.dailymail.co.uk/health/ar...rop
There are 9 fifteen-letter words containing 2A, F and 2U: AUTOTRANSFUSION COUNTERFACTUALS INFRASTRUCTURAL ... REMANUFACTURING SEMIMANUFACTURE ULTRAFASTIDIOUS. Every word on this site can be used while playing scrabble. Create other lists, that begin with or end with letters of your choice.
Surgeons always try to carry out surgery to minimise the amount of blood lost. In recent years, this has become easier, due to the increasing use of keyhole surgery (laparoscopic surgery), where only small cuts are made in the body.. However, some types of surgical operations and procedures have a higher risk of blood loss; therefore, a blood transfusion is more likely to be needed. It may be possible to use a procedure called intra-operative cell salvage. It collects your blood thats lost during the surgery, and it can be returned back to you. Ask your doctor or nurse if intra-operative cell salvage is appropriate for the type of surgery youre having.. Its no longer possible to routinely collect your own blood in advance of your surgery.. ...
Autologous Blood Injection (ABI) and Platelet Rich Plasma (PRP) injections involve injecting a patient s blood into damaged part of body for the treatment of tendinitis at Melbourne Radiology Clinic.
We report on the anesthetic management of a 69-year-old female Jehovahs Witness undergoing cardiopulmonary bypass to replace the ascending aorta; the patient refused transfusion of stored autologous or allogeneic blood products for religious reasons. The strategy involved preoperative hematopoiesis with recombinant human erythropoietin and iron, intraoperative acute normovolemic hemodilution, the use of a cell-saver system, administration of high-dose tranexamic acid, controlled hypotension, avoidance of low body temperature, simplification of the surgery, and lower blood dilution during cardiopulmonary bypass.
Autotransfusion Services is a unique specialty that includes collecting and returning shed blood from the surgical field to significantly reduce or eliminate the need for blood transfusions.
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Background Blood salvage systems help to minimize intraoperative transfusion of allogenic blood. So far no data is available on the use of argatroban for anticoagulation of such systems. We conducted...
In the acute normovolemic hemodilution group, intraoperative blood collection was performed to a target hemoglobin of 8.0 g/dL. Low central venous pressure anesthetic technique was used intraoperatively for both groups. A standardized transfusion protocol was applied to all patients intraoperatively and throughout the hospital stay.. The researchers randomized 63 patients to acute normovolemic hemodilution, and 67 to standard anesthetic management from 2004 to 2007.. Demographics, diagnoses, liver function, extent of resection, intraoperative blood loss, operative time, incidence and grade of complications, and length of hospital stay were similar between the 2 groups. The team found that acute normovolemic hemodilution reduced the overall allogeneic red cell transfusion rate by 50% compared with standard anesthetic management. Acute normovolemic hemodilution patients were less often transfused intraoperatively compared with the standard anesthetic management group.. The research team noted that ...
Autologous donations are donations that individuals give for their own use - for example, before a surgery. Learn more about autologous donations.
TY - CHAP. T1 - What is the evidence for using hemostatic agents in surgery?. AU - Erstad, Brian L. PY - 2005. Y1 - 2005. N2 - The pharmacological methods used to achieve systemic hemostasis have generated much discussion due to concerns of serious adverse effects (e.g., thromboembolic complications) and costs of therapy in addition to efficacy considerations. There are a limited number of well-controlled trials involving pharmacological hemostasis for spine surgery. In the largest doubleblinded randomized controlled trial to date involving spine surgery, there was a trend toward reduced homologous transfusion in patients receiving aprotinin, but the only statistically significant result (p,0.001) was a reduction in autologous red cell donations. The findings of this trial are important, since the investigators used a number of restrictive transfusion strategies (e.g., autologous donation, low hematocrit trigger for transfusion, blood-salvaging procedures with the exception of no cell saver) ...