Biological psychiatry or biopsychiatry is an approach to psychiatry that aims to understand mental disorder in terms of the biological function of the nervous system. It is interdisciplinary in its approach and draws on sciences such as neuroscience, psychopharmacology, biochemistry, genetics, epigenetics and physiology to investigate the biological bases of behavior and psychopathology. Biopsychiatry is that branch / speciality of medicine which deals with the study of biological function of the nervous system in mental disorders. While there is some overlap between biological psychiatry and neurology, the latter generally focuses on disorders where gross or visible pathology of the nervous system is apparent, such as epilepsy, cerebral palsy, encephalitis, neuritis, Parkinsons disease and multiple sclerosis. There is some overlap with neuropsychiatry, which typically deals with behavioral disturbances in the context of apparent brain disorder. In contrast biological psychiatry describes the ...
The Swiss Society of Biological Psychiatry is an association according to articles 60 ff of swiss civil law. It is a member of the World Federation of Societies of Biological Psychiatry (WFSBP) and associated with the Swiss Society of Psychiatry and Psychotherapy ...
Progress in Neuro-Psychopharmacology & Biological Psychiatry is a peer-reviewed academic journal publishing review articles and original research reports pertaining to neuropsychopharmacology and biological psychiatry. It was established in 1977 as Progress in Neuro-Psychopharmacology, obtaining its current name in 1982.[1][2] It is published eight times per year by Elsevier. The editor-in-chief is Louis Gendron (Université de Sherbrooke). According to the Journal Citation Reports, the journal has a 2018 impact factor of 4.315.[3] ...
Find, buy and download Neurosciences. Biological psychiatry. Neuropsychiatry ebooks from our Academic section for your eReader at great prices.
Find, buy and download Neurosciences. Biological psychiatry. Neuropsychiatry ebooks from our Academic section for your eReader at great prices.
1. Archive of General Psychiatry (2007-) 2. Molecular Psychiatry (2007-) 3. Biological Psychiatry (2006-) 4. Pharmacogenetics and Genomics (2006-) 5. Neuropsychopharmacology (2007-) 6. Drug and Alcohol Dependence (2006-) 7. American Journal of Medical Genetics B (2007-) 8. Psychiatric Genetics (2005-) 9. Neuroscience Letters (2005-) 10. Methods and Findings (2006-) 11. Alcohol Research & Health (2006-) 12. Alcoholism: Clinical and Experimental Research (2007-) 13. Genes, Brain and Behavior (2007-) 14. Schizophrenia research (2008-) 15. Psychopharmacology (2008-) 16. Alcohol - An International Biomedical Journal (2008-) 17. Progress in Neuro-Psychopharmacology & Biological Psychiatry (2008-) 18. Journal of Personality 19. BMC Psychiatry (2009-) 20. Addiction Biology (2010-) 21. Diabetes Research and Clinical Practice (2010-) 22. PLoS One (2011-) 23. The International Journal of Neuropsychopharmacology (2011-) 24. Journal of Clinical Psychiatry (2012-) 25. Human Psychopharmacology: Clinical and ...
I escaped lifelong mental illness prognoses by not believing a word of it even if the disorder label (schizoaffective) still sits in my notes to mark me out, to stigmatise and discriminate against me. I escaped mental illness 3 times and it was easier back in 1978 and 1984 to leave psychiatry behind. I was even helped by a community psychiatrist who came to my house in 1985, Rigside, Lanarkshire, supporting me in my plans to taper the Chlorpromazine and be off it within the year. Because I was determined to do it, had done it after the earlier puerperal psychosis. But in 2002 I was eventually made to take a drug cocktail of Risperidone, Venlafaxine and Lithium. There was coercion because of my lack of agency due to antipsychotics being forced on to me in Lomond Ward, Stratheden, the week I was a mental patient in around March 2002. A 72hr detention because I was resistant. They forced me and took away my agency. It took me around 2yrs to get back the strength to taper and make a full recovery. ...
Visit Healthgrades for information on Dr. Charles Parker, DO Find Phone & Address information, medical practice history, affiliated hospitals and more.
Widge, A. S., Zorowitz, S., Link, K., Miller, E. K., Deckersbach, T., Eskandar, E. N., & Dougherty, D. D. (2015). Ventral Capsule/Ventral Striatum Deep Brain Stimulation Does Not Consistently Diminish Occipital Cross-Frequency Coupling. Biological Psychiatry.. Widge, A. S., Arulpragasam, A. R., Deckersbach, T., & Dougherty, D. D. (2015). Deep brain stimulation for psychiatric disorders. Emerging trends in the social and behavioral sciences: An interdisciplinary, searchable, and linkable resource.. Widge, A.S., Deckersbach, T., Eskandar, E. N. & Dougherty, D. D. Deep Brain Stimulation for Treatment-Resistant Psychiatric Illnesses: What Has Gone Wrong and What Should We Do Next? Biological Psychiatry, 2015 Jun 10.. Widge, A. S., & Dougherty, D. D. (2015). Deep Brain Stimulation for Treatment-Refractory Mood and Obsessive-Compulsive Disorders. Current Behavioral Neuroscience Reports, 2(4), 187-197.. Nierenberg, A., Peters, A., Stange, J., Sylvia, L.G., Otto, M.W., Miklowitz, D.J., Dougherty, D.D., ...
Mohr, J.P. and Thompson, J.L.P. and Lazar, Ronald M. and Levin, Bruce and Sacco, R.L. and Furie, K.L. and Kistler, J.P. and Albers, G.W. and Pettigrew, L.C. and Adams, H.P. and Jackson, C.M. and Pullicino, Patrick (2001) A comparison of warfarin and aspirin for the prevention of recurrent ischemic stroke. New England Journal of Medicine, 345 (20). pp. 1444-1451. ISSN 1533-4406. (doi:https://doi.org/10.1056/NEJMoa011258) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided ...
Objectives. The primary aim of these guidelines was to evaluate the role of pharmacological agents in the treatment and management of paraphilia, with a focus on the treatment of adults males. Because such treatments are not delivered in isolation, the role of specific psychosocial and psychotherapeutic interventions was also briefly covered. These guidelines are intended for use in clinical practice by clinicians who diagnose and treat patients with paraphilia. The aim of these guidelines is to improve the quality of care and to aid physicians in clinical decisions. Methods. The aim of these guidelines was to bring together different views on the appropriate treatment of paraphilias from experts representing different continents. To achieve this aim, an extensive literature search was conducted using the English language literature indexed on MEDLINE/PubMed (1990-2009 for SSRIs) (1969-2009 for antiandrogen treatments), supplemented by other sources, including published reviews. Results. Each ...
From a new study in Biological Psychiatry. Many people with schizophrenia have marked problems with motivation, failing to initiate and persist in goal-directed behavior. These negative symptoms of schizophrenia can be disabling and prevent individuals from realizing their potential.. For many years it was thought this was due to an inability to experience pleasure associated with successful goal attainment. However, recent laboratory studies have shown that hedonic experience is actually intact in people with schizophrenia, calling for new approaches to better understand these motivational deficits.. In a new study published in Biological Psychiatry, Dr. James Gold, at the University of Maryland School of Medicine, and his colleagues now provide a new clue to the relationship between motivational deficits and functional impairment.. They theorized that the lack of motivation may stem from a decreased willingness to expend effort to gain rewards. In other words, individuals with schizophrenia ...
The consequences of the trials were promulgated in a scrap in Biological Psychiatry by Dr. Dragana Bugarski-Kirola of Roche Pharmaceuticals in Basal, Switzerland. The randomized, double-blind, parallel-group, placebo-controlled libraries were a collaboration between Roche and detached research installations about the the human scramble.. "We are backside to the sketch embark on," undignified Dr. John Krystal, Redactor of Biological Psychiatry.. Above-mentioned undertakings to analyse pessimistic earmarks compel ought to hired dopes, hormones, and brains stimulation, but no one bring into the world contributed the desired clinical edge. Research engineer glutamate signaling in denying symptoms has itchy the idea of end glutamate receptors, but this method has peter out in muscular pests. Glycine reuptake inhibitors upkeep been cogitate oned a encouraging alterative to augment glutamatergic signaling, and a humiliated proof-of-concept test showed that bitopertin, which selectively put an ends ...
Abstracts of the 72nd Annual Scientific Convention and Meeting of the Society of Biological Psychiatry (SOBP 2017), as published in Biological Psychiatry, 2017 / vol.81, iss.10 Suppl., pp. ...
TY - JOUR. T1 - Reply to. T2 - Citation distortions in the literature on the serotonin-transporter-linked polymorphic region and amygdala activation. AU - Kaufman, Joan. PY - 2015/10/15. Y1 - 2015/10/15. UR - http://www.scopus.com/inward/record.url?scp=84941811747&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=84941811747&partnerID=8YFLogxK. U2 - 10.1016/j.biopsych.2015.02.035. DO - 10.1016/j.biopsych.2015.02.035. M3 - Letter. C2 - 25840957. AN - SCOPUS:84941811747. VL - 78. SP - e37-e38. JO - Biological Psychiatry. JF - Biological Psychiatry. SN - 0006-3223. IS - 8. ER - ...
https://www.youtube.com/watch?enablejsapi=1&autoplay=0&cc_load_policy=0&iv_load_policy=1&loop=0&modestbranding=0&rel=1&fs=1&playsinline=0&autohide=2&theme=dark&color=red&controls=1&" class="__youtube_prefs__ no-lazyload" title="YouTube player" allow="autoplay; encrypted-media" allowfullscreen data-no-lazy="1" data-skipgform_ajax_framebjll ...
Exposure to stressful life events has been recognized as an important promoter of major psychiatric illness for many years (i.e., the classic diathesis-stress
Abell F, Krams M, Ashburner J, Passingham R, Friston K, Frackowiak R, Happe F, Frith C, Frith U (1999). The neuroanatomy of autism A voxel based whole brain analysis of structural scans. Neuroreport 10 1647-1651. Abitbol M, Menini C, Delezoide AL, Rhyner T, Vekemans M, Mallet J (1993). Nucleus basalis magnocellularis and hippocampus are the major sites of FMR-1 expression in the human fetal brain. Nat Genet 4 147-153. Alaghband-Rad J, McKenna K, Gordon CT, Albus KE, Hamburger SD, Rumsey JM,.... ...
Robert Morris University in Pittsburgh, Pa. offers a professionally focused education with an emphasis on engaged learning experiences.
If required by your instructor, you can add annotations to your citations. Just select Add Annotation while finalizing your citation. You can always edit a citation as well. ...
TY - JOUR. T1 - γ-melanotropin and β-endorphin after dexamethasone. AU - Meador-Woodruff, James H.. AU - Silk, Kenneth R.. AU - Kronfol, Ziad. AU - Watson, Stanley J.. AU - Akil, Huda. PY - 1989/4/1. Y1 - 1989/4/1. UR - http://www.scopus.com/inward/record.url?scp=0024652543&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0024652543&partnerID=8YFLogxK. U2 - 10.1016/0006-3223(89)90278-3. DO - 10.1016/0006-3223(89)90278-3. M3 - Letter. C2 - 2541805. AN - SCOPUS:0024652543. VL - 25. SP - 975. EP - 976. JO - Biological Psychiatry. JF - Biological Psychiatry. SN - 0006-3223. IS - 7. ER - ...
Psychiatry has evolved considerably from those days in the early 1970s. For example, in the 8th edition of Kaplan & Sadocks Comprehensive Textbook of Psychiatry, the "bible" of the psychiatric resident and medical student, the section on the psychodynamic view of anxiety is one of the shortest and contains almost no analytic theory. This is a sign of the times, as psychoanalysis is being marginalized in favor of biological psychiatry and cognitive-behavioral therapy, which has taken over as the most "evidence-based" form of non-medication therapy.. In the case of José, these changes would have important practical implications for treatment. Nowadays, in all likelihood, he would be treated with some combination of medication (probably one of the serotonergic agents in the Prozac family or possibly a benzodiazepine like Clonazepam) and a program of graded exposure to the feared situations known as Cognitive Behavioral Therapy. Ironically, this is what he ended up receiving anyway but the ...
Dr. Weinberger received his BA from Johns Hopkins University and MD from the University of Pennsylvania. After medical internship at UCLA-Harbor General Hospital, he did residencies in psychiatry at Harvard Medical School and in neurology at George Washington University and is board certified in both specialties. He was a research fellow at the NIMH in Richard Wyatt�s lab and became Chief of the Clinical Brain Disorders Branch in 1987. He is the recipient of the Research Prize of the World Federation of Societies of Biological Psychiatry, the Foundations Fund Prize from the American Psychiatric Association, and the Lieber Prize from NARSAD, and is a member of the Institute of Medicine of the National Academy of Sciences. The work of his lab focuses on basic neurobiological and genetic mechanisms of neuropsychiatric disorders, especially schizophrenia ...
i] Frodl T. et. Al. "Reduced hippocampal volume correlates with executive dysfunctioning in major depression" Journal of Psychiatry and Neuroscience 2006 Sep; 31(5): 316-325. (source). [ii] "Alternative medicine for depression" Harvard Medical School July 1, 2007 (source). [iii] Bhattacharya S.K., Bhattacharya A., Sairam K., "Ghosal S. Anxiolytic-antidepressant activity of Withania somnifera glycowithanolides: an experimental study." Phytomedicine 2000 Dec;7(6):463-9. (source). [iv] Maes M., Galecki P., Chang Y.S., Berk M. " A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness." Progress in Neuropsychopharmacology and Biological Psychiatry. 2011 Apr 29;35(3):676-92. (source). [v] Forester B.P., Zuo C.S., Ravichandran C., Harper D.G., Du F., Kim S., Cohen B.M., Renshaw P.F. "Coenzyme Q10 effects on creatine kinase activity and mood in geriatric bipolar depression." Journal of ...
Dr. Carrie Bearden received her Ph.D. in Clinical Psychology from the University of Pennsylvania and joined the UCLA faculty as Assistant Professor in the Department of Psychiatry & Biobehavioral Sciences at UCLA in 2003. She hold a secondary appointment in the Department of Psychology. She has received numerous awards and honors, including Young Investigator Awards from the International Congress for Schizophrenia Research and the National Alliance for Research on Schizophrenia and Affective Disorders (NARSAD), and the American College of Neuropsychopharmacology (ACNP), the A.E. Bennett Neuropsychiatric Research Award for Clinical Science in Biological Psychiatry, and the Samuel Gershon Junior Investigator Award from the International Society for Bipolar Disorders. Dr. Beardens research aims to understand genetic influences on brain structure in the development of psychosis, using converging methods to study cognition and neuroanatomy in clinical high-risk samples (e.g., adolescents at ...
September 3, 2009 /Press Release/ -- Mount Sinai researchers have found that real-time brain imaging suggests that patients with Borderline Personality Disorder (BPD) are physically unable to activate neurological networks that can help regulate emotion. The findings, by Harold W. Koenigsberg, MD, Professor of Psychiatry at Mount Sinai School of Medicine, were presented at the 11th International Congress of the International Society for the Study of Personality Disorders (ISSPD), held August 21 - 23 at The Mount Sinai Medical Center in New York. The research will also be published in the journal Biological Psychiatry.. Using functional magnetic resonance imaging (MRI), Dr. Koenigsberg observed how the brains of people with BPD reacted to social and emotional stimuli. He found that when people with BPD attempted to control and reduce their reactions to disturbing emotional scenes, the anterior cingulated cortex and intraparetical sulci areas of the brain that are active in healthy people under ...
Curious about acupuncture, but not crazy about needles? Electroacupuncture may be in your future. Instead of needles, the technique uses a small electric current and conductive pads to stimulate acupuncture points. "You just feel a warm vibration and a slight tingle, and thats it," says electroacupuncturist George A. Ulett, M.D., clinical professor of psychiatry at the Missouri Institute of Mental Health in St. Louis. Dr. Ulett has been studying acupuncture since a trip to China in the late Sixties, and practicing electroacupuncture for almost 20 years. In two recent studies (Southern Medical Journal, 12/98; Biological Psychiatry, 7/15/98) he reports that the procedure can greatly reduce--and in some cases eliminate--the need to take drugs for arthritis pain, backaches, migraines, depression, anxiety, addictions, digestive disorders, and other ailments. Often called evidence-based acupuncture, electroacupuncture bypasses the traditional Eastern notion that acupuncture works by correcting ...
Susannah Cahalan is the New York Times bestselling author of Brain on Fire: My Month of Madness. She serves as a book reviewer at the New York Post an dis working on a new book that delves into the modern history of psychiatry, The Committed, out in 2018. Her award-winning work has appeared in the Psychology Today, Scientific American, Elle, BBC Focus Magazine, and Biological Psychiatry. She has been featured a number of radio and television shows, including The Today Show, The Katie Couric Show, and NPRs Fresh Air. She received a Yale Poynter fellowship in journalism and was Northeasterns 12th Annual Hanson Memorial Lecturer in 2016. In 2009, she was honored with the Silurian Award of Excellence for her article "My Mysterious Lost Month of Madness," on which Brain on Fire is based, and in 2012 received the Books for a Better Life Award for First Book ...
Sabatini, B. L., Svoboda, K. (2000) Analysis of calcium channels in single spines using optical fluctuation analysis. Nature, 408 (6812). pp. 589-593. ISSN 0028-0836 Sacktor, T. C., Osten, P., Valsamis, H., Jiang, X., Naik, M. U., Sublette, E. (1993) Persistent activation of the ζ isoform of protein kinase C in the maintenance of long-term potentiation. Proceedings of the National Academy of Sciences of the United States of America, 90 (18). pp. 8342-8346. ISSN 00278424 (ISSN) Sartorius, A., Neumann-Haefelin, C., Vollmayr, B., Hoehn, M., Henn, F. A. (2003) Choline rise in the rat hippocampus induced by electroconvulsive shock treatment. Biological Psychiatry, 53 (7). pp. 620-3. ISSN 0006-3223 Sartorius, A., Schloss, P., Vollmayr, B., Ende, G., Neumann-Haefelin, C., Hoehn, M., Henn, F. A. (2006) Correlation between MR-spectroscopic rat hippocampal choline levels and phospholipase A2. World J Biol Psychiatry, 7 (4). pp. 246-50. ISSN 1562-2975 (Print)1562-2975 (Linking) Schmitt, A., Weber, S., ...
People with major depressive disorder have alterations in the activity and connectivity of brain systems underlying reward and memory, according to a new study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. The findings provide clues as to which regions of the brain could be at the root of symptoms, such as reduced happiness and pleasure, in depression.
Our research program lies at the intersection between biological psychiatry and cognitive neuroscience with developmental and social cognition components. Our broad research goals are to specify and understand neurobiological bases of psychoses and in doing so, to further elucidate neural underpinnings of normal cognitive processes. Since early 1990s, we have focused on understanding the nature of cognitive deficits of schizophrenia (e.g. deficits in working memory, attention, oculomotor control, thought) to elucidate the relationships among behavioral signs, brain abnormalities and psychotic symptoms. We work with observable and quantifiable behaviors that can clearly differentiate patients with schizophrenia from healthy people and we try to understand the neural origins and behavioral consequences of these differences. Our earlier studies of working memory deficit in schizophrenia have played a significant role in establishing cognitive impairments as core features of schizophrenia (e.g. Park ...
Neural Plasticity is a peer-reviewed, Open Access journal that publishes articles related to all aspects of neural plasticity, with special emphasis on its functional significance as reflected in behavior and in psychopathology. Neural Plasticity publishes research and review articles from the entire range of relevant disciplines, including basic neuroscience, behavioral neuroscience, cognitive neuroscience, biological psychology, and biological psychiatry.
Neural Plasticity is a peer-reviewed, Open Access journal that publishes articles related to all aspects of neural plasticity, with special emphasis on its functional significance as reflected in behavior and in psychopathology. Neural Plasticity publishes research and review articles from the entire range of relevant disciplines, including basic neuroscience, behavioral neuroscience, cognitive neuroscience, biological psychology, and biological psychiatry.
Researchers at Boston University School of Medicine and the VA Boston Healthcare System are one step closer to understanding the specific nature of brain changes associated with posttraumatic stress disorder (PTSD). The findings, which appear in the journal Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, may lead to better diagnosis and treatment of the condition.
A study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging examines the neural signatures of restricted and repetitive behaviors in infancy
Encoding of Contextual Fear Memory Requires De Novo Proteins in the Prelimbic Cortex. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 2017 ...
... ) - Parsippany, NJ, July, 2013 - Obsessive-compulsive disorder affects about 2 million Americans, according to the National Institute of Mental Health. OCD is a distressing and often disabling condition characterized by overwhelming anxiety that drives the need to check things repeatedly or to perform certain rituals over and over. OCD is generally treated with psychotherapy, medication or both. "Unfortunately, many patients often struggle with the decision of which treatment options to pursue," says Dr. Francine Rosenberg, clinical psychologist and OCD specialist with The Morris Psychological Group in Parsippany, N.J. A new study published online in April 2013 in the journal Progress in Neuro-Psychopharmacology & Biological Psychiatry has the potential to open avenues to new understanding and treatment of OCD in people. Its been known for some time that dogs with canine compulsive disorder exhibit similar behaviors to people with OCD. This research shows that changes in the ...
Dr. Daniel Pine is chief of the Section on Development and Affective Neuroscience in the National Institute of Mental Health Intramural Research Program. Dr. Pine moved to this position in 2000, after 10 years of training, teaching and research at Columbia University. Since graduating from medical school at the University of Chicago, Dr. Pine has been engaged continuously in research on pediatric mental disorders, as reflected in more than 500 peer-reviewed papers. Currently, his group examines the degree to which pediatric mood and anxiety disorders are associated with perturbed neural circuitry function. Dr. Pine served as the chair of the Psychopharmacologic Drug Advisory Committee for the Food and Drug Administration, chair of the Child and Adolescent Disorders Work Group for the DSM-5 Task Force, and president of the Society of Biological Psychiatry. He is a member of the Institute of Medicine of the National Academy of Sciences and has received many other awards.. CME ...
Background:. A major research finding in the field of Biological Psychiatry is that symptom-based categories of mental disorders map poorly onto dysfunctions in brain circuits or neurobiological pathways. Many of the identified (neuro)biological dysfunctions are transdiagnostic, meaning that they do not reflect diagnostic boundaries but are shared by different ICD/DSM diagnoses. The compromised biological validity of the current classification system for mental disorders impedes rather than supports the development of treatments that not only target symptoms but also the underlying pathophysiological mechanisms. The Biological Classification of Mental Disorders (BeCOME) study aims to identify biology-based classes of mental disorders that improve the translation of novel biomedical findings into tailored clinical applications.. Methods:. BeCOME intends to include at least 1000 affected individuals (recruited through advertisements/self-referral or visits in the institutes outpatient clinic or ...
Schizophrenia, a type of psychosis, is something that can be as debilitating as its poorly understood. At present, its uncertain how much of it is down to genetics, and how much is down to environmental factors.. A new study, published in the journal Biological Psychiatry, has now claimed that nearly 80 percent of the risk factor for schizophrenia is genetic. Science, of course, is decided by consensus, not just a single study, so its important not to blow these results out of proportion. So whatre the facts behind the scary-sounding headlines?. The study, which was carried out by researchers from the Center for Neuropsychiatric Schizophrenia Research at Copenhagen University Hospital, took an interesting approach to identifying the causes of this condition: it used twins, along with a database on psychiatric patients. Known as a twin cohort study, this piece of research actually used both identical twins and non-identical twins.. As marvelously explained by the NHS, these studies provide ...
Jan Naegele, professor of biology, professor of neuroscience and behavior, made two presentations in 2013. On March 12, she spoke on "Promises and Pitfalls of Stem Cell Therapy for Brain Disorders" at the 17th Annual Meeting for the Israeli Society for Biological Psychiatry in Kibbutz Hagoshrim, Israel.. On March 26, she spoke to the Middlesex Elderly Service Providers on "Stem Cell Therapy for Brain Disorders" in Middletown.. On June 11, Naegele will speak on "GABAergic interneuron replacement for temporal lobe epilepsy" at the University of California-Irvine.. ...
A new study published in Biological Psychiatry suggests that autism is associated with reductions in the level of cellular adhesion molecules in the blood, where they play a role in immune function.. Cell adhesion molecules are the glue that binds cells together in the body. Deficits in adhesion molecules would be expected to compromise processes at the interfaces between cells, influencing tissue integrity and cell-to-cell signaling. In the brain, deficits in adhesion molecules could compromise brain development and communication between nerve cells.. Over the years, deficits in neural cell adhesion molecules have been implicated in schizophrenia and other psychiatric disorders. One adhesion molecule, neurexin, is strongly implicated in the heritable risk for autism.. Cell adhesion molecules also play a crucial role in regulating immune cell access to the central nervous system. Prior research provided evidence of immune system dysfunction in individuals diagnosed with autism spectrum disorder ...
However, it is not clear why hypoxia increases the risk for schizophrenia. The November 1st issue of Biological Psychiatry includes an article by researchers who show that the presence of a specific indicator of fetal distress following hypoxia was more likely to be present among people who later develop schizophrenia. Their findings suggest that the inability of a high-risk fetus to respond adequately to metabolic stresses that it faces in the womb may contribute to its later risk for developing schizophrenia.. Specifically, the authors analyzed levels of an important neuroprotective protein - brain-derived neurotrophic factor (BDNF) - in umbilical cord and maternal blood serum samples obtained at the time of birth and stored in a repository for 45-50 years. They then compared the levels of BDNF found among those individuals who had developed schizophrenia during their lifetime to control subjects, i.e., those individuals who did not develop the disorder. Dr. Tyrone Cannon, the corresponding ...
Scientists may be a step closer to having a good target for drugs that could treat at least some cases of the misery-rendering malady of obsessive-compulsive disorder. A new study in the journal Biological Psychiatry finds that when a certain receptor in the brain goes into warp overdrive, it causes symptoms in mice that look a lot like OCD in humans: The rodents cant stop licking and grooming themselves. They also showed signs of anxiety. Whats more, when the researchers took the receptor activity back down to normal levels, the OCD behavior went away in minutes. "[This] raises the possibility that this receptor and its signaling pathway in the brain may have a role in people with compulsive behavioral problems," said senior author Nicole Calakos, MD, PhD, associate professor of neurology and neurobiology at Duke University Medical Center in Durham, North Carolina. "A really important next step is finding just which people and just which problem." RELATED: How Can I Tell If I Have OCD?. More ...
Peer-Reviewed Publications 2019 28. Kalfic K, Mitchell G, Ooi L, Schwab SG, Matosin N*. Overcoming the deficiency of refugee mental health research. Retrieved from psyarxiv.com/g5rx7. Undergoing revisions *Corresponding author 2018 27. Matosin N, Halldorsdottir T, Binder EB. Understanding the molecular mechanisms underpinning G×E interactions in psychiatric disorders: the FKBP5 model. Biological Psychiatry. 2018. 83 (10),…
Abercrombie, H.C., Schaefer, S.M., Larson, C.L., Oakes, T.R., Lindgren, K.A., Holden, J.E., . . . Davidson, R.J. (1998). Metabolic rate in the right amygdala predicts negative affect in depressed patients. NeuroReport, 9, 3301-3307.. Abercrombie, P.D., Zamora, A., & Korn, A.P. (2007). Lessons learned: Providing a mindfulness-based stress reduction program for low-income multiethnic women with abnormal pap smears. Holistic Nursing Practice, 21, 26-34.. Aftanas, L.I., & Golocheikine, S.A. (2002). Non-linear dynamic complexity of the human EEG during meditation. Neuroscience Letters, 330, 143-146.. Allman, J.M.,Watson, K.K.,Tetreault, N.A., & Hakeem,A.Y. (2005). Intuition and autism: A possible role for Von Economo neurons. Trends in Cognitive Sciences, 9, 367-373.. Anand, A., Li, Y., Wang, Y., Wu, J., Gao, S., Bukhari, L., . . . Lowe, M.J. (2005). Activity and connectivity of brain mood regulating circuit in depression:Afunctional magnetic resonance study. Biological Psychiatry, 57, ...
A mental disorder or mental illness is a psychological or behavioral pattern generally associated with subjective distress or disability that occurs in an individual, and which is not a part of normal development or culture. Such a disorder may consist of a combination of affective, behavioural, cognitive and perceptual components. The recognition and understanding of mental health conditions have changed over time and across cultures, and there are still variations in the definition, assessment, and classification of mental disorders, although standard guideline criteria are widely accepted. A few mental disorders are diagnosed based on the harm to others, regardless of the subjects perception of distress. Over a third of people in most countries report meeting criteria for the major categories at some point in their lives. The causes are often explained in terms of a diathesis-stress model or biopsychosocial model. In biological psychiatry, mental disorders are conceptualized as disorders of ...
Molecules to Mind : A Joint Annual Meeting of the Union of the Swiss Societies for Experimental Research, Swiss Society for Neuroscience and Swiss Society of Biological Psychiatry : February 17th to 19th, ETH Zürich ...
Wang, Shuo and Jiang, Ming and Duchesne, Xavier Morin et al. (2015) Atypical Visual Saliency in Autism Spectrum Disorder Quantified through Model-Based Eye Tracking. Neuron, 88 (3). pp. 604-616. ISSN 0896-6273. PMCID PMC4662072. https://resolver.caltech.edu/CaltechAUTHORS:20151023-130102765 Pantelis, Peter C. and Byrge, Lisa and Tyszka, J. Michael et al. (2015) A specific hypoactivation of right temporo-parietal junction/posterior superior temporal sulcus in response to socially awkward situations in autism. Social Cognitive and Affective Neuroscience, 10 (10). pp. 1348-1356. ISSN 1749-5016. PMCID PMC4590532. https://resolver.caltech.edu/CaltechAUTHORS:20150305-103507972 Kennedy, Daniel P. and Paul, Lynn K. and Adolphs, Ralph (2015) Brain Connectivity in Autism: The Significance of Null Findings. Biological Psychiatry, 78 (2). pp. 81-82. ISSN 0006-3223. https://resolver.caltech.edu/CaltechAUTHORS:20150701-100317677 Byrge, Lisa and Dubois, Julien and Tyszka, J. Michael et al. (2015) Idiosyncratic ...
BF Psychology ; RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry ; RZ Other systems of medicine ; T Technology (General)
PubMedID: 25981171 | Altered Expression of CDC42 Signaling Pathway Components in Cortical Layer 3 Pyramidal Cells in Schizophrenia. | Biological Psychiatry | 12/1/2015
Bandelow, Borwin; Baldwin, David; Abelli, Marianna; Altamura, Carlo; DellOsso, Bernardo; Domschke, Katharina; Fineberg, Naomi A; Grünblatt, Edna; Jarema, Marek; Maron, Eduard; Nutt, David; Pini, Stefano; Vaghi, Matilde M; Wichniak, Adam; Zai, Gwyneth; Riederer, Peter (2016). Biological markers for anxiety disorders, OCD and PTSD - a consensus statement. Part I: Neuroimaging and genetics. World Journal of Biological Psychiatry, 17(5):321-365.. Bandelow, Borwin; Baldwin, David; Abelli, Marianna; Bolea-Alamanac, Blanca; Bourin, Michel; Chamberlain, Samuel R; Cinosi, Eduardo; Davies, Simon; Domschke, Katharina; Fineberg, Naomi; Grünblatt, Edna; Jarema, Marek; Kim, Yong-Ku; Maron, Eduard; Masdrakis, Vasileios; Mikova, Olya; Nutt, David; Pallanti, Stefano; Pini, Stefano; Ströhle, Andreas; Thibaut, Florence; Vaghi, Matilde M; Won, Eunsoo; Wedekind, Dirk; Wichniak, Adam; Woolley, Jade; Zwanzger, Peter; Riederer, Peter (2016). Biological markers for anxiety disorders, OCD and PTSD: A consensus ...
American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed. text revision). Washington, DC: Author.. Barkley, R.A. (1998, Sept.). Attention deficit hyperactivity disorder. Scientific American. Barry, L.M. & Messer, J.J. (2003). A practical application of self-management for students diagnosed with attention-deficit/hyperactivity disorder. Journal of Positive Behavior Interventions, 5, 238-248.. B sen, A. (2000, October 10). Dagens Medicin, 41.. Bolanos, C.A., Barrot, M, Berton, O, Wallace-Black, D, Nestler, E.J. (2003). Methylphenidate treatment during pre-and periadolescence alters behavioral responses to emotional stimuli at adulthood. Biological Psychiatry, 54(12), 1317-1329.. Brandon, C.L., Marinelli, M., Baker, L.K., White, F.J. (2001). Enhanced reactivity and vulnerability to cocaine following methylphenidate treatment in adolescent rats. Neuropsychopharmacology, 25(5), 651-661. Brandon, C., & Steiner, H. (2003). Repeated methylphenidate ...
Although both bipolar disorder and chronic depression have multiple similarities, they also have some key differences. Plagued by extreme sadness or profound emptiness, depression can make even the most cheerful person feel hopeless and restless, taking away his zeal for life. Whereas, people suffering from bipolar disorder are known to oscillate between manic episodes and severe depression. No wonder, both the conditions are often misdiagnosed as major depression.. Now, a study by researchers from Illinois Loyola University suggests that both depression and bipolar disorder can be distinguished from each other by monitoring the patients heartbeat. For the study published recently in the World Journal of Biological Psychiatry, the researchers examined 64 adults suffering from severe depression and 37 others grappling with bipolar disorder. All the 101 subjects were made to undergo electrocardiograms for a duration of 15 minutes, the results of which were analyzed subsequently using ...
Professor Peretz Lavie was born in Petach Tikva in 1949 and raised in Zichron Yaacov. He started his academic studies at the Psychology and Statistics Departments of the Tel Aviv University. He received his formal training in sleep research and sleep medicine at American universities. In 1975 he joined the Faculty of Medicine at the Technion - Israel Institute of Technology, where he founded the Sleep Research Laboratory and the Center for Sleep Medicine. He served as head of the Unit of Behavioral Biology in the Faculty of Medicine and head of the Technion Research Center for Work Safety and Human Engineering, as well as dean of the Faculty of Medicine. He currently holds the André Ballard Chair in Biological Psychiatry, and has served as the Technions Vice President for Resource Development and External Relations since 2001.. His research over the years was dedicated to sleep and sleep disorders. In order to describe periods of the day marked by changes in levels of alertness and the way in ...
Recommended anxiety disorder medications are listed and reviewed. Includes definition and symptoms of anxiety, efficacy, side effects dosing, mechanism, and interactions of drugs for the treatment of anxiety disorders. Based on World Federation of Societies of Biological Psychiatry expert guidelines.
Biological psychiatry research has long focused on the brain in elucidating the neurobiological mechanisms of anxiety- and trauma-related disorders. A review challenges this assumption and suggests that the gut microbiome and its interactome also deserve attention to understand brain disorders and develop innovative treatments and diagnostics in the 21st century. The recent, in-depth characterization of the human microbiome spurred a paradigm shift in human health and disease. Animal models strongly suggest a role for the gut microbiome in anxiety- and trauma-related disorders. The microbiota-gut-brain (MGB) axis sits at the epicenter of this new approach to mental health. The microbiome plays an important role in the programming of the hypothalamic-pituitary-adrenal (HPA) axis early in life, and stress reactivity over the life span.[1]
Turner, N., Monterrubio, S., Meyer, B. J. & Solowij, N. 2006, Fatty acid relationships in former cannabis users with schizophrenia, Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol. 30, no. 2, pp. 280-285.. ...
In a new study by Keiho Owada and colleagues, 18 people with autism spectrum disorders had more neutral facial expressions and fewer surprised expressions than 17 typically developing people while interacting socially. Oxytocin, a hormone that promotes social bonding, was delivered to the autism group via a nasal spray for six weeks, and made the faces of the people with autism more expressive. Oxytocin also improved their reciprocity in social interactions and increased activity in the dorsomedial prefrontal cortex, as observed via functional magnetic resonance imaging (fMRI).. The study suggests not only that oxytocin can normalize facial expressions, but also that the counting of facial expressions on videos of social interactions can be used as a measure of social symptoms of autism. The research was presented at the 2016 meeting of the Society of Biological Psychiatry.. ...
Philadelphia, PA, November 19, 2013 /3BL Media/ - Two years ago, mammalian target of rapamycin or mTOR, a signaling protein, was identified as a key mediator of the antidepressant effects of ketamine, the first rapidly acting antidepressant medication to be identified.. Several years later, a group at the National Institutes of Mental Health Intramural Program reported that scopolamine, a muscarinic acetylcholine receptor antagonist, also produced rapidly appearing antidepressant effects, similar to the actions of ketamine.. Together these findings represent one of the most significant advances in the field of depression in recent years.. Now, new results reported in the current issue of Biological Psychiatry by researchers at the Yale University School of Medicine demonstrate that scopolamine causes rapid activation of mTOR signaling and increased number of synaptic connections in the prefrontal cortex.. The prefrontal cortex is an important brain region, involved in executive and cognitive ...
Depression? Mixed evidence from a variety of research studies. Psychosis? Inconclusive research; 2005 research in Biological Psychiatry described a common gene that makes cannabis five times more likely to trigger schizophrenia; 25% of the population have this gene15% of this group are likely to develop psychotic conditions if exposed to cannabis early in life.. Arseneault et al concluded that heavy cannabis use (regular and long-term) contributes as one of many factors, forming a "causal constellation" of factors including psychological vulnerability and genetics.. The self medication hypothesis has been discounted. Aggression: Using is associated with decrease aggression unless taken in periods of high stress. CARDIOVASCULAR SYSTEM: Increase heart rate. ...
Sanchis-Segura, C., Spanagel, R., Henn, F. A., Vollmayr, B. (2005) Reduced sensitivity to sucrose in rats bred for helplessness: a study using the matching law. Behav Pharmacol, 16 (4). pp. 267-70. ISSN 0955-8810 (Print)0955-8810 (Linking) Sartorius, A., Henn, F. A. (2007) Deep brain stimulation of the lateral habenula in treatment resistant major depression. Med Hypotheses, 69 (6). pp. 1305-8. ISSN 0306-9877 (Print)0306-9877 (Linking) Sartorius, A., Henn, F. A. (2005) [Treating depressive disorders with continuation electroconvulsive therapy]. Nervenarzt, 76 (11). pp. 1363-9. ISSN 0028-2804 (Print)0028-2804 (Linking) Sartorius, A., Kiening, K. L., Kirsch, P., von Gall, C. C., Haberkorn, U., Unterberg, A. W., Henn, F. A., Meyer-Lindenberg, A. (2010) Remission of major depression under deep brain stimulation of the lateral habenula in a therapy-refractory patient. Biological Psychiatry, 67 (2). e9-e11. ISSN 0006-3223 Sartorius, A., Mahlstedt, M. M., Vollmayr, B., Henn, F. A., Ende, G. (2007) ...
Clinical guidelines on the management of depression in patients with psychiatric comorbidities were published in January 2019 by the French Association for Biological Psychiatry and Neuropsychopharmac... more
1. Protopopescu X, Tuescher O, Pan H, Goldstein M, Cloitre M, Gorman J, Ledoux JE, Engelien W, Silbersweig D, Stern E: Differential time-courses and specificity of amygdala activation in PTSD subjects and normal controls. Biological Psychiatry, 57: 464-473, 2005.. 2. Protopopescu X, Pan H, Tuescher O, Cloitre M, Goldstein M, Engelien A, Yang Y, Gorman J, LeDoux J, Stern E, Silbersweig D. Increased brainstem volume in Panic Disorder: a voxel-based morphometric study, Neuroreport 17: 361-363, 2006.. 3. Tuescher O, Protopopescu X, Pan H, Cloitre M, Butler T, Goldstein M, Root JC, Engelien A, Furman D, Silverman M, Yang Y, Gorman J, LeDoux J, Silbersweig D, Stern E. Differential activity of rostral cingulate and brainstem in panic disorder and PTSD. J Anxiety Disorders. 2010 Oct 10; 1201: 1-7. In press.. 4. Butler T, Pan H, Epstein J, Protopopescu X, Tuescher O, Goldstein M, Cloitre M, Yang Y, Phelps E, Gorman J, Ledoux J, Stern E, Silbersweig D. Fear-related activity in subgenual anterior cingulate ...
Reducing the function of the autism-associated gene Pcdh10 leads to impairments in social behavior, according to a study published in Biological Psychiatry. Reducing Pcdh10 function also disrupted the structure and function ...
Ivanova, S. A., Osmanova, D. Z., Freidin, M. B., Fedorenko, O. Y., Boiko, A. S., Pozhidaev, I. V., ... Loonen, A. J. M. (2017). Identification of 5-hydroxytryptamine receptor gene polymorphisms modulating hyperprolactinaemia in antipsychotic drug-treated patients with schizophrenia. The World Journal of Biological Psychiatry, 18(3), 239-246. DOI: 10.1080/15622975.2016.1224926 ...
Research indicates that cognitive behavior therapy (CBT) is an effective treatment for up to 60% of patients with Major Depressive Disorder (MDD). However, some patients are more likely to remit than others, depending on the severity of the disorder. It is important and beneficial to patients, clinicians, and third-party payers alike, therefore, that scientists identify those who will most likely benefit from treatment.. One facet of CBT treatment involves interrupting the "downward spiral" of automatic negative thoughts. While neuroimaging has shown that CBT influences this type of brain activity via sustained limbic activity and decreased prefrontal function, functional magnetic resonance imaging (fMRI) can be costly and time-consuming. A recent study by Siegle, et al. published in Biological Psychiatry proposes that pupillary response to negative words may be a cost-effective measure to predict the likelihood of remission for certain depressed patients treated with CBT. Previous research has ...
Leday, G. G. R., Vértes, P. E., Richardson, S., Greene, J. R., Regan, T., Khan, S., Henderson, R., Freeman, T. C., Pariante, C. M., Harrison, N. A., Cardinal, R., Hume, D., Wu, Z., Cattaneo, A., Zunszain, P., Borsini, A., Stewart, R., Chandran, D., Carvalho, L., Bell, J. & 11 others, Souza-Teodoro, L., Perry, H., Harrison, N., Drevets, W., Wittenberg, G., Jones, D., Stylianou, A., Perry, V. H., Drevets, W. C., Wittenberg, G. M. & Bullmore, E. T., 9 Jul 2017, In : Biological psychiatry.. Research output: Contribution to journal › Article ...
A small study published in June 2006 in Biological Psychiatry suggests that autism spectrum disorders may result from abnormal early fetal development.. Scientists looked at preserved placentas from children later diagnosed with autism, and compared them to placentas of children with normal development. The placentas from autistic children were 3 times more likely to contain "trophoblastic inclusions." (Trophoblasts are among the first cells to form during fetal development, and are essential for implantation and placental development.) Trophoblast inclusions have been associated with a number of other genetic abnormalities, and the presence of trophoblasts in fully-formed placentas may not affect their function, but could be markers for genetic predispositions "that could have subtle, yet profound, effects in the developing embryo an the forming nervous system.". ...
According to a study of mice, conducted by researchers at Tufts University School of Medicine (TUSM) in Boston and published in Biological Psychiatry, a womans risk of developing out-of-the-norm social behavior and anxiety or stress may be partly due to the events which took place in her fathers life when he was younger ...
Swalve and Li, M* (2012): Parametric studies of antipsychotic-induced sensitization in the conditioned avoidance response model: Roles of number of drug exposure, drug dose, and test-retest interval, Behavioural Pharmacology, 2012 Aug;23(4):380-91 Abstract. Li, M*, He, W, and Munro, R (2012): Differential effects of acute amphetamine and phencyclidine treatment and withdrawal from repeated amphetamine or phencyclidine treatment on social interaction and social memory in rats, PsyCh Journal, 2012 Jun;1(1):56-68 Abstract. Zhao, CJ, Sun, T and Li, M* (2012): Neural basis of the potentiated inhibition of repeated haloperidol and clozapine treatment on the phencyclidine-induced hyperlocomotion, Progress in Neuropsychopharmacology & Biological Psychiatry, 2012 Aug 7;38(2):175-82 Abstract. Zhang, C and Li, M* (2012): Contextual and behavioral control of antipsychotic sensitization induced by haloperidol and olanzapine, Behavioural Pharmacology, Feb;23(1):66-79. Abstract. Li, M*, Sun, T, and Mead, A ...
BUFFALO, N.Y. - Neuroscientists know that cocaine addiction and withdrawal rewire the brain. But figuring out how to disrupt those changes to treat addiction requires an extremely detailed understanding of how those changes occur.. Now, in a paper published recently in Biological Psychiatry, researchers at the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo have identified an important piece in the puzzle.. Led by David M. Dietz, PhD, associate professor in the Department of Pharmacology and Toxicology at UB, the team has discovered that a protein in the brains reward center, the nucleus accumbens, regulates genes that help drive the craving for cocaine after a period of withdrawal. Zi-jun Wang, PhD, a postdoctoral fellow in the department, is first author.. The work is funded by a grant awarded in 2014 to Dietz from the National Institute on Drug Abuse to study the short- and long-term neurobiological changes - known as neuroplasticity - induced by cocaine ...
Bandelow, B., Baldwin, D., Abelli, M., Bolea-Alamanac, B., Bourin, M., Chamberlain, S. R., Cinosi, E., Davies, S., Domschke, K., Fineberg, N., Grünblatt, E., Jarema, M., Kim, Y. K., Maron, E., Masdrakis, V., Mikova, O., Nutt, D., Pallanti, S., Pini, S., Ströhle, A. & 8 others, Thibaut, F., Vaghi, M. M., Won, E., Wedekind, D., Wichniak, A., Woolley, J., Zwanzger, P. & Riederer, P., 15 Jul 2016, In : World Journal of Biological Psychiatry. 18, 3, p. 162-214 53 p.. Research output: Contribution to journal › Review article ...
Chronic and severely stressful situations, like those connected to depression and posttraumatic stress disorder, have been associated with smaller volumes in stress sensitive brain regions, such as the cingulate region of the cerebral cortex and the hippocampus, a brain region involved in memory formation. A new study, published by Elsevier in Biological Psychiatry, suggests that chronic insomnia may be another condition associated with reduced cortical volume. Using a specialized technique called voxel-based morphometry, Ellemarije Altena and Ysbrand van der Werf from the research group of Eus van Someren evaluated the brain volumes of persons with chronic insomnia who were otherwise psychiatrically healthy, and compared them to healthy persons without sleep problems. They found that insomnia patients had a smaller volume of gray matter in the left orbitofrontal cortex, which was strongly correlated with their subjective severity of insomnia.. We show, for the first time, that insomnia ...
Benton, D. and Cook, R. (1991) Selenium supplementation improves mood in a souble-blind crossover trial. Biological Psychiatry 29, pp.1092-98. Gilbody, S., Lightfoot, T. and Sheldon, T. (2007) Is low folate a risk factor for depression? A meta-analysis and exploration of heterogeneity. Journal of Epidemiol Community Health 61, pp.631-637. Hulsken S, Martin A, Mohajeri MH, Homberg JR (2013) Food-derived serotonergic modulators: effects on mood and cognition. Nutrition Research Reviews, 26, 223-234. Nabb, S. and Benton, D. (2006) The influence on cognition and mood of the interaction between the macro-nutrient content of breakfast and glucose tolerance. Physiology and Behavior 87, pp.16-23. Rayman, MP. (2000) The importance of selenium to human health. Lancet 356, pp.233-41. Rogers, PJ. (2007) Review: Caffeine, mood and mental performance in everyday life. Nutrition Bulletin 32, pp.84-89. Rose, N., Koperski, S. and Golomb, B. (2010), Chocolate and depressive symptoms in a cross-sectional analysis. ...
The rate of psychiatric illness among children who lost a parent in the Sept. 11, 2001, World Trade Center attack doubled -- from about 32 to nearly 73 percent -- in the years following the event, according to a new study in the journal Biological Psychiatry. The study was conducted by researchers at NewYork-Presbyterian Hospital/Weill Cornell Medical Center ...
JERUSALEM--(BUSINESS WIRE)--May 17 2007 - BioLineRx Ltd. (TASE:BLRX)...-- Society of Biological Psychiatry Annual Convention May 17-19(San ...-- American Psychiatric Association Annual Meeting May 19-24(San Die...-- New Clinical Drug Evaluation Unit Annual (NCDEU) MeetingJune 11-1...The abstract which has been selected for these posterpresentations de...,BioLineRx,Presents,Phase,I,Clinical,Data,of,BL-1020,at,Upcoming,Clinical,Conferences,medicine,advanced medical technology,medical laboratory technology,medical device technology,latest medical technology,Health
Oxytocin, a hormone that promotes emotional bonding, also benefits people having trouble dealing with stress. A new study suggests that giving oxytocin for a week shortly following a traumatic experience reduces the risk that the recipient will develop post-traumatic stress disorder (PTSD).. In the study by researcher Mirjam van Zuiden and colleagues, people who visited an emergency room following some kind of trauma were randomized to receive either a placebo nasal spray or intranasal oxytocin twice daily for 7.5 days beginning within 12 days after the trauma. The dosage was 40 IU twice daily.. For those participants with severe PTSD symptoms at baseline, repeated oxytocin administration prevented worsening PTSD. The research was presented at the 2016 meeting of the Society of Biological Psychiatry.. ...
Inflammation is the bodys response to injury and cellular disruption. It is linked to heart disease, diabetes and cancer. Physicians routinely screen for inflammation with blood tests such as C-reactive protein and nuclear factor (NF)-KB. A study from UCLA found that disturbed sleep, even for a few hours, triggered inflammation in the bodys cells and organs. The scientists found that (NF)-KB levels were lower after a good nights sleep compared to partial sleep deprivation, in which people stayed awake between 11 p.m. and 3 a.m. Sleep deprivation is linked to a variety of health problems including obesity, heart disease, arthritis, diabetes and some cancers. America is a high-stress society in which most people dont get enough sleep. We could be paying for it with our health. (Biological Psychiatry, 64: 538-540). ...
Major depression is a very common mental condition, with 6.7 percent of all adults in the United States having had at least one severe depressive episode in 2014 or 2015.. According to the World Health Organization (WHO), depression is also currently the leading causeof years spent with disability worldwide.. Some people diagnosed with major depression experience suicidal thoughts, which may result in suicide attempts. In the U.S., "suicide is the 10th leading cause of death." Now, researchers wonder whether or not suicidal ideation in people with major depression may be linked to abnormal inflammation of the brain.. Dr. Peter Talbot and other researchers based at the University of Manchester in the United Kingdom have conducted a study testing the levels of a biomarker associated with brain inflammation in the systems of people diagnosed with clinical depression.. The scientists findings were reported in the journal Biological Psychiatry.. "This paper is an important addition to the view that ...
People with recurrent depressions or those exposed to chronic stress exhibits shorter telomeres in white blood cells. This is shown by a research team at Umeå University in a coming issue of Biological Psychiatry.
Link to NIHMS profile:. http://www.ncbi.nlm.nih.gov/myncbi/browse/collection/40412936/?sort=date&direction=ascending. A Hishimoto, H Nomaru, K Ye, A Nishi, J Lim, JT Aguilan, E Nieves, G Kang, R Hogue Angeletti, and N Hiroi. Molecular histochemistry identifies peptidomic organization and reorganization along striatal projection units. Biological Psychiatry (2016) PMID 26520239 El Bissati K, Suvorova ES, Xiao H, Lucas O, Upadhya R, Ma Y, Hogue AngelettiR, White MW, Weiss LM, Kim K. Toxoplasma gondii Arginine Methyltransferase 1(PRMT1) Is Necessary for Centrosome Dynamics during Tachyzoite Cell Division. MBio. 2016 7. PMC4742710.. Outhiriaradjou Benard, Jihyeon Lim, Pasha Apontes, Xiaohong Jing, Ruth H Angeletti, Yuling Chi. Impact of high-fat diet on the proteome of mouse liver http://dx.doi.org/10.1016/j.jnutbio.2015.12.012. Nika H, Angeletti RH, Hawke DH. Phosphopeptide Enrichment by Covalent Chromatography After Solid Phase Derivatization of Protein Digests on Reversed Phase Supports. Methods ...
Carlson, Alexander L.; Xia, Kai; Azcarate-Peril, M. Andrea; Goldman, Barbara D.; Ahn, Mihye; Styner, Martin A.; Thompson, Amanda L.; Geng, Xiujuan; Gilmore, John H.; & Knickmeyer, Rebecca C. (2018). Infant Gut Microbiome Associated with Cognitive Development. Biological Psychiatry, 83(2), 148-59. PMCID: PMC5724966. Cho, Hyunsan; Mbai, Isabella; Luseno, Winnie Kavulani; Hobbs, Marcia M.; Halpern, Carolyn Tucker; & Hallfors, Denise Dion. (2018). School Support as Structural HIV Prevention for Adolescent Orphans in Western Kenya. Journal of Adolescent Health, 62(1), 44-51. PMCID: PMC5742035. Choi, Jaeun; Zeng, Donglin; Olshan, Andrew F.; & Cai, Jianwen. (2018). Joint Modeling of Survival Time and Longitudinal Outcomes with Flexible Random Effects. Lifetime Data Analysis, 24(1), 126-52. PMCID: PMC5756108. Croffut, Samantha E.; Hamela, Gloria; Mofolo, Innocent A.; Maman, Suzanne; Hosseinipour, Mina C.; Hoffman, Irving F.; Bentley, Margaret E.; & Flax, Valerie L. (2018). HIV-Positive Malawian Women ...
Author(s): Ferrier NI, Blamire AM, Cousins DA. Publication type: Letter. Publication status: Published. Journal: Biological Psychiatry. Year: 2013. Volume: 74. Issue: 12. Pages: e41-e42. Print publication date: 15/12/2013. Online publication date: 30/08/2013. ISSN (print): 0006-3223. ISSN (electronic): 1873-2402. Publisher: ELSEVIER SCIENCE INC. URL: http://dx.doi.org/10.1016/j.biopsych.2013.07.023. DOI: 10.1016/j.biopsych.2013.07.023. ...
In addition, Michael holds the elected office of Immediate Past President of Association of Faculties of Pharmacy of Canada since May 2010. Dr. Namaka is a co-founder along with Dr. Karen Ethans of the Manitoba Multiple Sclerosis Research Network Organization (MMSRNO). Currently, Dr. Namaka is the acting President of this organization. Internationally, Dr. Namaka also holds the official appointment (Oct 2015) as an Adjunct Professor at the Third Military Medical University in Chongqing, China as well as an official appointment (Oct 2015) as a Principle Investigator to the Joint Laboratory of Biological Psychiatry between the Shantou University Medical College Guangdong, China and the College of Medicine at the University of Manitoba ...
Chidambaram, S. B., Rathipriya, A. G., Bolla, S. R., Bhat, A., Ray, B., Mahalakshmi, A. M., Manivasagam, T., Thenmozhi, A. J., Essa, M. M., Guillemin, G. J., Chandra, R. & Sakharkar, M. K., Jun 8 2019, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 92, p. 161-193 33 p.. Research output: Contribution to journal › Review article ...
Pan, A. Y., Ryu, E., Geske, J. R., Zhou, X. Y., McElroy, S. L., Cicek, M. S., Frye, M. A., Biernacka, J. M. & Andreazza, A. C., Jan 1 2019, (Accepted/In press) In : World Journal of Biological Psychiatry.. Research output: Contribution to journal › Article ...
Aagten-Murphy, D., Attucci, C., Daniel, N., Klaric, E., Burr, D., & Pellicano, E. (2015). Numerical estimation in children with autism. Autism Research, 8, 668-681.. Assumpção, L., Shi, Z., Zang, X., Müller, H. J., & Geyer, T. (2015). Contextual cueing: implicit memory of tactile context facilitates tactile search. Attention, Perception & Psychophysics, 77, 1212-1222.. Bocca, F., Töllner, T., Müller, H. J. & Taylor, P. (2015). The right angular gyrus combines perceptual and response-related expectancies in visual search: TMS-EEG evidence. Brain Stimulation, 8, 816-822.. Cross-Villasana, F., Finke, K., Hennig-Fast, K., Kilian, B., Wiegand, I., Müller, H. J., Möller, H-J., & Töllner, T. (2015). The speed of visual attention and motor-response decisions in adult attention deficit/hyperactivity disorder. Biological Psychiatry, 78, 107-115.. Finke, K., Neitzel, J., Bäuml, J. G. Redel, P. Müller, H. J., Meng, C. Jaekel, J. Daamen, M. Scheef, L., Busch, B., Baumann, N. Boecker, H., Bartmann, ...
Want something else to worry about? Worry about worrying too much. The evidence is building that chronically elevated stress shrinks your brain! A |a href=http://www.ncbi.nlm.nih.gov/pubmed/22218286|study|/a| in press at the journal Biological Psychiatry |em||/em|asked 103 people about how often they had experienced stressful events, both recently ...
A new study in Biological Psychiatry finds hallmarks of cellular aging in people who have experienced early life stress, depression, anxiety, or substance abuse. The relationship seen between psychopathology and shortened telomeres confirmed earlier reports, and this paper presents the first evidence of altered mitochondrial biogenesis, including increased mtDNA copy number, in people with early…
A recent issue published by the journal Biological Psychiatry has reviewed various research papers to address the question whether food could be considered an addition.
Posted on October 5, 2015 By Ilia Elenkov Blogs. A recent study published in the journal Biological Psychiatry indicates the presence of aberrant cytokine levels in patients with suicidality, and identifies a link between pro-inflammatory cytokines, and specifically, interleukin (IL)-1β and IL-6 with suicidal behavior. Previous research has shown that major depression is associated with an immune response with an increased production of pro-inflammatory […] ...
Sonuga-Barke, E J S; Kumsta, R; Schlotz, W; Lasky-Su, J; Marco, R; Miranda, A; Mulas, F; Oades, R D; Banaschewski, T; Mueller, U; Andreou, P; Christiansen, H; Gabriels, I; Uebel, H; Kuntsi, J; Franke, B; Buitelaar, J; Ebstein, R; Gill, M; Anney, R; Roeyers, H; Rothenberger, A; Sergeant, J; Steinhausen, H C; Asherson, P; Faraone, S V (2011). A functional variant of the serotonin transporter gene (SLC6A4) moderates impulsive choice in attention-deficit/hyperactivity disorder boys and siblings. Biological Psychiatry, 70(3):230-236.. Marco, R; Miranda, A; Schlotz, W; Meliá, A; Mulligan, A; Müller, U; Andreou, P; Butler, L; Christiansen, H; Gabriels, I; Medad, S; Albrecht, B; Uebel, H; Asherson, P; Banaschewski, T; Gill, M; Kuntsi, J; Mulas, F; Oades, R D; Roeyers, H; Steinhausen, H C; Rothenberger, A; Faraone, S V; Sonuga-Barke, E (2009). Delay and reward choice in ADHD: An experimental test of the role of delay aversion. Neuropsychology, 23(3):367-380.. Mulligan, A; Anney, R J; ORegan, M; Chen, ...
J. D. Bremner; R. B. Innis; T. White; M. Fujita; D. Silbersweig; A. W. Goddard; L. Staib; E. Stern; A. Cappiello; S. Woods; R. Baldwin; D. S. Charney. SPECT [I-123]iomazenil measurement of the benzodiazepine receptor in panic disorder. Biological Psychiatry 47(2):96-106, 2000. PMID: 10664825. WOBIB: 126. ...
Rao, H., Gillihan, S. J., Wang, J., Korczykowski, M., Sankoorikal, G. M. V., … Farah, M. J. (2007). Genetic variation in serotonin transporter alters resting brain function in healthy individuals. Biological Psychiatry, 62, 600-606.. ...
A new study in Biological Psychiatry investigates the molecular basis for male predisposition to autism Exposure to androgens during brain development...
Maes, Michael, Mihaylova, Ivana, Kubera, Marta and Ringel, Karl 2012, Activation of cell-mediated immunity in depression : association with inflammation, melancholia, clinical staging and the fatigue and somatic symptom cluster of depression, Progress in neuro-psychopharmacology and biological psychiatry, vol. 36, no. 1, pp. 169-175, doi: 10.1016/j.pnpbp.2011.09.006. ...
1. Attention, memory and learning are impaired among heavy marijuana users, even after users discontinued its use for at least 24 hours. Heavy marijuana use is associated with residual neuropsychological effects even after a day of supervised abstinence from the drug. Heavy users displayed significantly greater impairment than light users on attention/executive functions, as evidenced particularly by greater preservations on card sorting and reduced learning of word lists. These differences remained after controlling for potential confounding variables, such as estimated levels of premorbid cognitive functioning, and for use of alcohol and other substances in the two groups. However, the question remains open as to whether this impairment is due to a residue of drug in the brain, a withdrawal effect from the drug, or a frank neurotoxic effect of the drug. ("The Residual Cognitive Effects of Heavy Marijuana Use in College Students," Pope, HG Jr., Yurgelun-Todd, D., Biological Psychiatry ...
Patel S, Shonesy BC, Bluett RJ, Winder DG, Colbran RJ. The Anxiolytic Actions of 2-Arachidonoylglycerol: Converging Evidence From Two Recent Genetic Endocannabinoid Deficiency Models. Biological psychiatry. 2016 May 15;79(10). e78-9. PMID: 26212898 [PubMed]. ...
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