Prebiotics, such as short- and long-chain fructo-oligosaccharides are fermented by the microflora colonizing the gastrointestinal tract, and they selectively stimulate the growth or the activity of one or limited number of bacteria within the intestine. Beta-glucans are polysaccharides occurring in the bran of cereal grains, the cell wall of Saccharomyces cerevisiae and bacteria, certain types of fungi, seaweed and many kinds of mushrooms. The aim of this study is to determine the effect of the potential prebiotic beta-glucan on the intestinal microflora, the bacterial enzyme activity (beta-glucuronidase and beta-glucosidase) in the faeces, the faecal pH, and the concentration of faecal short-chain fatty acid in polypectomized patients ...
Yeast Beta Glucan Oat Beta Glucan Beta Glucan Beta-1,3/1,6-D-glucan Beta-1,3/1,4-D-glucan Beta-1,3-D-glucan Yeast Beta Glucan Powder Oat Beta Glucan Powder
250 mg of Beta-Glucans Supports Normal Immune Function* With Larch Arabinogalactan Beta-1,3/1,6 D-Glucan (Beta-Glucans) is a bioactive carbohydrate derived from
β-(1,3)/(1,6) D-glucan, a component of the fungal cell wall, has been shown to stimulate the immune system, enhance hematopoiesis, amplify killing of opsonized tumor cells and increase neutrophil chemotaxis and adhesion. In view of these attributes, the β-glucans should be studied for both their therapeutic efficacy in patients with cancer as well as an adjunctive therapy in patients receiving chemotherapy as a maneuver to limit suppression of hematopoiesis. In this study, twenty patients with advanced malignancies receiving chemotherapy were given a β-(1,3)/(1,6) D-glucan preparation (MacroForce plus IP6, ImmuDyne, Inc.) and monitored for tolerability and effect on hematopoiesis. Our results lead us to conclude that β-glucan is well-tolerated in cancer patients receiving chemotherapy, may have a beneficial effect on hematopoiesis in these patients and should be studied further, especially in patients with chronic lymphocytic leukemia and lymphoma.
A glucan molecule is a polysaccharide of D-glucose monomers, linked by glycosidic bonds. Many beta-glucans are medically important. They represent a drug target for antifungal medications of the echinocandin class. The following are glucans: (The α- and β- and numbers clarify the type of O-glycosidic bond.) dextran, α-1,6-glucan with α-1,3-branches floridean starch, α-1,4- and α-1,6-glucan glycogen, α-1,4- and α-1,6-glucan pullulan, α-1,4- and α-1,6-glucan starch, a mixture of amylose and amylopectin, both α-1,4- and α-1,6-glucans cellulose, β-1,4-glucan chrysolaminarin, β-1,3-glucan curdlan, β-1,3-glucan laminarin, β-1,3- and β-1,6-glucan lentinan, a strictly purified β-1,6:β-1,3-glucan from Lentinus edodes lichenin, β-1,3- and β-1,4-glucan oat beta-glucan, β-1,3- and β-1,4-glucan pleuran, β-1,3- and β-1,6-glucan isolated from Pleurotus ostreatus zymosan, β-1,3-glucan Properties of glucans include resistance to oral acids/enzyme and water insolubility. Glucans ...
Soluble fiber known as beta-D-glucan. These compounds are usually referred to as beta-glucans, and they comprise a class of non-digestible polysaccharides widely found in nature in such sources as oats, barley, yeast, bacteria, algae and mushrooms. Oat beta-glucan is a soluble fiber located mainly in cell walls that is a viscous polysaccharide made up of units of the sugar D-glucose. Studies have shown that a healthy diet that includes beta-glucan can aid in maintaining normal levels of blood cholesterol and glucose.. The exact mechanism of beta-glucans possible hypocholesterolemic effect is not clear. It appears to promote increased excretion of bile acids, which could help explain its possible cholesterol moderating activity. Beta-glucan may also promote cholesterol clearance from the plasma via reverse cholesterol transport.. The mechanism of the glucose-regulatory activity of beta-glucan is also not well understood. Beta-glucan may delay gastric emptying time and consequently affect the ...
Soluble fiber known as beta-D-glucan. These compounds are usually referred to as beta-glucans, and they comprise a class of non-digestible polysaccharides widely found in nature in such sources as oats, barley, yeast, bacteria, algae and mushrooms. Oat beta-glucan is a soluble fiber located mainly in cell walls that is a viscous polysaccharide made up of units of the sugar D-glucose. Studies have shown that a healthy diet that includes beta-glucan can aid in maintaining normal levels of blood cholesterol and glucose.. The exact mechanism of beta-glucans possible hypocholesterolemic effect is not clear. It appears to promote increased excretion of bile acids, which could help explain its possible cholesterol moderating activity. Beta-glucan may also promote cholesterol clearance from the plasma via reverse cholesterol transport.. The mechanism of the glucose-regulatory activity of beta-glucan is also not well understood. Beta-glucan may delay gastric emptying time and consequently affect the ...
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A search for genes which, at elevated copy number, could suppress the growth defect in a strain disrupted at the KRE9 locus has identified the SKN7 gene. SKN7 was mapped to the right arm of chromosome VIII and is predicted to encode a 70-kDa protein, Skn7p, with a region of homology to the DNA binding domain of the Saccharomyces cerevisiae heat shock transcription factor, Hsf1p. Skn7p also has a domain which shows similarity to the prokaryotic receiver modules found on an extensive family of two-component response regulators, including the products of the rcsC and barA genes. SKN7 did not suppress other mutations in the (1--,6)-beta-glucan biosynthetic pathway, suggesting that SKN7 does not act as a general bypass suppressor of this glucan. ...
A characterization of the S. cerevisiae KRE6 and SKN1 gene products extends previous genetic studies on their role in (1--,6)-beta-glucan biosynthesis (Roemer, T., and H. Bussey. 1991. Yeast beta-glucan synthesis: KRE6 encodes a predicted type II membrane protein required for glucan synthesis in vivo and for glucan synthase activity in vitro. Proc. Natl. Acad. Sci. USA. 88:11295-11299; Roemer, T., S. Delaney, and H. Bussey. 1993. SKN1 and KRE6 define a pair of functional homologs encoding putative membrane proteins involved in beta-glucan synthesis. Mol. Cell. Biol. 13:4039-4048). KRE6 and SKN1 are predicted to encode homologous proteins that participate in assembly of the cell wall polymer (1--,6)-beta-glucan. KRE6 and SKN1 encode phosphorylated integral-membrane glycoproteins, with Kre6p likely localized within a Golgi subcompartment. Deletion of both these genes is shown to result in a dramatic disorganization of cell wall ultrastructure. Consistent with their direct role in the assembly of ...
To investigate the role of β-(1-3)-D-glucan on 99mTc labelled Escherichia coli translocation and cytokines secretion in rats submitted to small bowel ischemia/reperfusion injury. Methods: Five groups (n=10 each) of Wistar rats were subjected to control(C), sham(S), group IR subjected to 45 min of bowel ischemia/60 min of reperfusion(I/R), and group I/R+glucan subjected to 45 min of bowel ischemia/60 min of reperfusion(I/R) and injected with 2mg/Kg intramuscular. Translocation of labelled bacteria to mesenteric lymph nodes, liver, spleen, lung and serum was determined using radioactivity/count and colony forming units/g(CFU/g). Serum TNFα, IL-1β, IL-6, IL-10 were measured by ELISA. Results: CFU/g and radioactivity/count were higher in I/R than in I/R+glucan rats. In C, S and S+glucan groups, bacteria and radioactivity/count were rarely detected. The I/R+glucan rats had enhancement of IL-10 and suppressed production of serum TNFα, IL-1β and, IL-6, compared to I/R untreated animals. ...
Associates of Cape Cod,Inc.(ACC),manufactures the Fungitell® Assay,the Gold Standard in Rapid Screening For Invasive Fungal Infection (IFI).Fungitell® is the first and only FDA-cleared & CE marked rapid in vitro diagnostic screening test for IFI (including Candida, Aspergillus & Pneumocystis) that detects (1→3)-β-D-Glucan in serum. ACC operates Beacon Diagnostics® Laboratory, a CLIA-certified reference laboratory specializing in (1→3)-β-D-Glucan analysis services to support the diagnosis (IFI).. ...
2. Plasma (1→3)-ß-D-glucan and fungal antigenemia in patients with candidemia, aspergillosis, and cryptococcosis.. T Miyazaki, S Kohno, K Mitsutake, S Maesaki, K Tanaka, N Ishikawa, and K Hara. Second Department of Internal Medicine, Nagasaki University School of Medicine, Japan. (1→3)-ß-D-Glucan is one of the major structural components of fungi, and it seems that it can be detected by the fractionated (1→3)-ß-D-glucan-sensitive component from a Limulus lysate, factor G. We evaluated the concentration of (1→3)-ß-D-glucan by using factor G and other fungal antigens in 24 patients with clinical evidence of mycosis and 36 healthy subjects. The mean concentration of (1→3)-ß-D-glucan in the plasma of the healthy subjects was found to be 2.7 +/- 1.9 pg/mL (range, < 6.9 pg/mL), and it was found to be substantially higher in all 11 patients with candidemia (mean, 2,207.4 pg/mL; range, 325.4 to 8,449.0 pg/mL). Eight of those 11 patients with candidemia (73%) were positive for the Cand-Tec ...
NOW® Beta-1,3/1,6-D-Glucan (beta-glukan)je bioaktivni polisaharid, izoliran iz celične stene pivskega kvasa (Saccharomyces cerevisiae). Znanstvene študije ...
Read "Structure-function relationships of β- D-glucan endo- and exohydrolases from higher plants, Plant Molecular Biology" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
beta-Glucans: Glucose polymers consisting of a backbone of beta(1->3)-linked beta-D-glucopyranosyl units with beta(1->6) linked side chains of various lengths. They are a major component of the CELL WALL of organisms and of soluble DIETARY FIBER.
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Invasive candidiasis is associated with high mortality, particularly in adults. Retrospective studies show that shorter times to treatment are correlated with a lower risk of death. A number of factors can be used to predict which patients would benefit from antifungal prophylaxis or early (pre-emptive or empirical) therapy. Detection of the fungal cell wall component (1-->3)-beta-D-glucan (BDG) shows promise as an early biomarker of invasive fungal infection and may be useful in identifying patients who would benefit from early antifungal treatment. To date, no consistent early treatment strategy has evolved. Proof-of-concept studies are needed to assess the role of pre-emptive and empirical therapy in ICU patients and the relevance of BDG as an early marker of infection ...
Three different families of pattern recognition receptors, toll-like (TLRs), Nod-like (NLRs), and RIG-I-like, initiate innate immunity, the inborn host response to common pathogens such as viruses, bacteria, and fungi. These receptors recognize and bind pathogen-associated molecular patterns (PAMPs) such as viral DNA and RNA, or bacterial and fungal cell wall components. PAMP-receptor binding activates the innate immune response, initiates downstream signaling, and induces expression of inflammatory cytokines as well as the type-I interferon response. The innate immune system attracts immune cells to the site of infection, and activates the adaptive immune response. This initial immune response is essential to combat a novel foreign pathogen. Dysregulation of innate immune processes can lead to widespread infection, sepsis, and immunodeficiencies ...
Three different families of pattern recognition receptors, toll-like (TLRs), Nod-like (NLRs), and RIG-I-like, initiate innate immunity, the inborn host response to common pathogens such as viruses, bacteria, and fungi. These receptors recognize and bind pathogen-associated molecular patterns (PAMPs) such as viral DNA and RNA, or bacterial and fungal cell wall components. PAMP-receptor binding activates the innate immune response, initiates downstream signaling, and induces expression of inflammatory cytokines as well as the type-I interferon response. The innate immune system attracts immune cells to the site of infection, and activates the adaptive immune response. This initial immune response is essential to combat a novel foreign pathogen. Dysregulation of innate immune processes can lead to widespread infection, sepsis, and immunodeficiencies ...
The nutraceutical potential of β-d-glucan is largely dependent on its structure, size and viscosity. The present study analyzed the effect of germination and microwave processing of barley on the structural, size, antioxidant and thermal characteristics of β-d-glucan. The molecular weight and viscosity of β-d-glucan obtained from germinated barley (GGB) were the lowest (144kDa and 37.33cp) as comp ...
A strong immune system is vital to the preservation of your good health. Transfer Points Beta glucan has been subjected to rigorous studies at numerous universities, and is the most potent, best Beta Glucan available on the market today. Beta Glucan has been found to build the immune system. Your immune system is designed to fight off illness and disease, so it is important that you do everything possible to strengthen your immune system. This is the Beta Glucan recommended in the book Cancer Free by Bill Henderson. Beta Glucan also offers health benefits for the cardiovascular system, blood glucose levels, and weight management.Transfer Points Beta Glucan, has been demonstrated repeatedly to be the most potent and efficacious Beta 1,3D glucan available on the market today. ...
Cultivated for more than 1,000 years, these meaty, tender Chinese mushrooms have long served as both food and medicine. They owe their reputation as immunity boosters to a type of carbohydrate called beta-glucans. Unlike other immunity nutrients, beta-glucans dont create or regulate cells within your immune system. Instead, they act as a kind of decoy, boosting your bodys immune response. When you eat shiitakes, your immune system reacts as if a harmful substance is present and kicks into high gear to protect you. In a 2004 animal study of swine influenza virus, the group given beta-glucans before infection developed a much milder case of the flu than those untreated. While the swine flu virus study was not the same strain as the human H1N1 virus, the results show promise for beta-glucans ability to prevent and treat the flu ...
Immune builder is a full spectrum beta glucan formula, combining all of the beta glucan structures known to exist in medicinal mushrooms. This includes Beta 1-3 Glucan, Beta 1-6, 1-3 Glucan, Beta 1-4, 1-3, 1-6 Glucan and Beta 1-6 Glucan.. Each beta glucan utilizes a unique and distinct "signaling pathway" when when triggering or modulating the non-specific immune response. By combining all the known beta glucan configurations, we are utilizing all the known pathways and may be producing a more complex and effective immune response for daily immune support.*. Just one capsule twice a day, AM and PM, on an empty stomach, provides the full prophylactic dose of MaitakeGold, plus an additional 20% (the amount for daily tonic immune support is 4 mg twice a day, Immune Builder contains 5 mg of MaitakeGold in each capsule). Adding the other four beta glucan combinations, in addition to the Beta 1-6, 1-3 Glucan supplied by the Maitake, ensures best effect for daily immune support.*. Immune Builder is the ...
Accepted name: polysaccharide O-methyltransferase. Reaction: S-adenosyl-L-methionine + (1→4)-α-D-glucooligosaccharide = S-adenosyl-L-homocysteine + oligosaccharide containing 6-methyl-D-glucose units. Other name(s): polysaccharide methyltransferase; acylpolysacharide 6-methyltransferase; S-adenosyl-L-methionine:1,4-α-D-glucan 6-O-methyltransferase. Systematic name: S-adenosyl-L-methionine:(1→4)-α-D-glucan 6-O-methyltransferase. Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37205-56-4. References: 1. Ferguson, J.A. and Ballou, C.E. Biosynthesis of a mycobacterial lipopolysaccharide. Properties of the polysaccharide methyltransferase. J. Biol. Chem. 245 (1970) 4213-4223. [PMID: 5503262]. ...
... is a fiber-type sugar molecule that can help control cholesterol levels. It is commonly found in bakers yeast, which is the richest concentrated source. It is the key ingredient in the cholesterol-lowering effect proven in oat bran. It is also found in wheat and barley and medicinal mushrooms.. If you have been diagnosed with high cholesterol, you will want-with the help of your doctor, of course-to consider all the possibilities for treatment in reducing those levels. Studies indicate that beta glucans are worth considering. On your own, incorporating them into your diet shouldnt be too difficult. Make the soups a bit more exotic in the variety of mushrooms you use and make them robust and thick with barley. Have oatmeal for breakfast in the cold weather. Try homemade bread with whole grains and let the bakers yeast raise the dough for you.. ...
If you have to cope with severe physical stress - for example, because you train hard - supplementation with beta glucans may at the same time reduce fatigue and keep your immune system strong. An animal study that recently appeared in the Open Biochemistry Journal suggests this.
Altered extent of cross-linking of beta1,6-glucosylated mannoproteins to chitin in Saccharomyces cerevisiae mutants with reduced cell wall beta1,3-glucan conten
Beta-Glucan is a polysaccharide naturally found in bakers yeast and other natural foods. Yeast Beta-Glucan has the ability to enhance immune defenses, and may complement other nutrients to promote stronger immune health. Yeast Beta-Glucan helps promote better immunity for your childs continuous learning opportunities. For more information on Wellmune® Beta-Glucan please visit: http://www.wellmune.com/
A healthy component of beta-glucan pasta is able to fight against high cholesterol when consuming 3 grams per day. High cholesterol is a risk factor for coronary heart disease progression. Beta-glucan is a special squeezing of oats, a 100% natural ingredient which prevents heart attack. A niche product is meant to meet the demands of the target audience for the unique properties of a familiar product. The line of tomato, spinach, whole meal and buckwheat pasta was supplemented with oatmeal spaghetti and fusilli. LIVINGOOD are products that help to stay young and to feel good. The macaroni LIVINGOOD ingredients include natural vegetable and cereal supplements and oat beta-glucan. ...
Oats are one of the quintessential foods of the traditional Scottish diet. In terms of health benefits they are best known for their fibre content, particularly their beta-glucan content. Less well known is that this humble grain contains a unique class of more than twenty polyphenols known as avenanthramides, not found in any other foods. In recent…
Beta glucans,is a natural water-soluble fiber (1,3/1,4) β-glucan, It is a viscous polysaccharide made up of units of the monosaccharide D-glucose.And its effects on health specifically on both serum cholesterol and blood glucose reduction is proven.
Increasing oats and beta-glucan extract intake has been associated with improved glycemic control, which is associated with the reduction in the development of diabetes. This study aims to assess the different effects between oat (whole and bran) and beta-glucan extract intake on glycemic control an …
Mushrooms contain long-chain polysaccharides, specifically alpha- and beta-glucans. These molecules have beneficial effects on your immune system. In fact, medications like penicillin, streptomycin, and tetracycline are all derived from fungal extracts ...
The chemical reactions and pathways resulting in the formation of (1-|3)-beta-D-glucans, compounds composed of glucose residues linked by (1-|3)-beta-D-glucosidic bonds.
For just-weaned piglets, it is essential to receive protein sources that are highly digestible. Not every source is available everywhere, due to legislation restrictions. Yeast-derived protein does not have harmful side effects and is well-researched.
Ok, question for everyone. I figured out today that whole grain pancakes with a sugar free syrup makes my bg jump. Was at 107 when I got up check level agai...
glucan sulfate: RN given refers to (1-3)-beta-D-glucan hydrogen sulfate; empirical formula of the glucan sulfate repeating unit is(C6-H10-O5)8 3SO3NH4(+) 4H2O; see also curdlan sulfate
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. ...
Learn more about Beta-Glucan at Grand Strand Medical Center Alternate Names Oat bran Uses Principal Proposed Uses High Cholesterol Other Proposed Uses Immune...
This powerful immune-boosting supplement helps the body defend against and increase healing from about every kind of disease and stress. Taking Beta-Glucan ...
*Thank you Marjorie for sending us the review!. JKosmmune Product Review by Marjorie I recently won samples of Jkosmmune enzyme powder cleanser, serum and lotion in exchange for my honest opinion. This brand is known for using natural and pure Beta-glucan in their products.Beta glucan is getting a lot of buzz lately. I
i spent the past few days in the hospital...i had a dka attack. my bg levels were out of control ( over 700 is all they said when i was admitted. ) i even ha...
Id really like to investigate the effect of protein in a meal on BG levels. I had a bacon & egg sarnie (very naughty) for lunch today. My BG was just under 5 beforehand. 2 hours after the meal, it was 2.8. 2 hours later still, its 12.2! Is that the result of the large amount of protein involved? If not theres something else seriously wrong which Im going to have to determine... thanks, Karen -- * "2002: A Discworld Odyssey" * August 16th-19th, 2002 * * Web: http://www.dwcon.org/ * Email: email @ redacted * ---------------------------------------------------------- for HELP or to subscribe/unsubscribe, contact: [email protected] help SUPPORT Insulin Pumpers http://www.insulin-pumpers.org/donate.shtml ...
Borland, Jim; Moir, Will; Udall, Rob; Steinkamp, Myrna P.; Root, Peter; Naumann, Tamara; Jennings, Bill; and Kelley, Reed, "Aquilegia, Vol. 14 No. 1, January-February 1990: Newsletter of the Colorado Native Plant Society" (1990). Aquilegia - Colorado Native Plant Society. 51 ...
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Immune response relies on the stimulation of macrophages white blood cells that scour the body on search and destroy missions targeting harmful bacteria. Unfortunately, these special forces are not always on duty - they must first be activated. And that s the role of beta-glucans. They give the go order to the body s macrophages. The more beta-glucans in the system, the more macrophages will be called into action. NOW Beta 1-3 Glucan formula is comprised of the most concentrated sources available Saccharomyces Cerevisae (the inner cell walls of baker s yeast) and Maitake mushroom. As research evolves, consumers are increasingly turning to beta-glucans to give their immune function added firepower ...
Beta Glucan is one of the most powerful immune enhancer known to science. A vital part of a good supplement program, there are many benefits in taking Beta Glucan. It strengthens our immune system, has anti-tumor activity, helps to normalize our blood fats, heals your skin, and supports normal blood sugar and insulin levels.. Beta Glucan is a chain of glucose molecules, found in foods like yeasts, oats, barley and mushrooms. Every time we eat these foods we consume beta glucan. We do not, however, consume enough of it in our daily diets to reap its excellent benefits.. Large white blood cells in our body, destroy bacteria, dead and dying cells, mutated cells, and other dangerous invaders in the blood stream. These white blood cells are the most important thing in our immune system and studies have proven that Beta Glucan strengthens and activates these cells.. Taking beta glucan is an excellent way to ensure you and your children are in the best possible health.. The results of numerous clinical ...
Cytokinesis is a crucial event in the cell cycle of all living cells. In fungal cells, it requires co-ordinated contraction of an actomyosin ring and synthesis of both plasmatic membrane and a septum structure that will constitute the new cell wall end. Schizosaccharomyces pombe contains four essential putative (1,3)β-d-glucan synthase catalytic subunits, Bgs1p to Bgs4p. Here we examined the function of Bgs1p in septation by studying the lethal phenotypes of bgs1(+) shut-off and bgs1Delta cells and demonstrated that Bgs1p is responsible and essential for linear (1,3)β-d-glucan and primary septum formation. bgs1(+) shut-off generates a more than 300-fold Bgs1p reduction, but the septa still present large amounts of disorganized linear (1,3)β-d-glucan and partial primary septa. Conversely, both structures are absent in bgs1Delta cells, where there is no Bgs1p. The septum analysis of bgs1(+)-repressed cells indicates that linear (1,3)β-d-glucan is necessary but not sufficient for primary septum ...