Apollo Master Health Check (AMHC) - One Day Package is recommended for persons between 30-60 years of age.It is especially recommended for individuals who have risk factors such as Hypertension,Diabetes Mellitus,History of smoking ,Obesity and those with a stressful Lifestyle.
Apollo Master Health Check (AMHC) - One Day Package is recommended for persons between 30-60 years of age.It is especially recommended for individuals who have risk factors such as Hypertension,Diabetes Mellitus,History of smoking ,Obesity and those with a stressful Lifestyle.
Primary hypertrophic cardiomyopathy (HCM) is a genetic cardiac disease characterized by thickening (hypertrophy) of the left ventricular (LV) wall, dyspnea and/or fatigue in the setting of a normal or supra-normal LV ejection fraction. The specific mechanisms underlying heart failure-related symptomatology in non-obstructive HCM are poorly defined, but as the vast majority of HCM patients with heart failure have apparently preserved LV contractile function, their symptoms of dyspnea and fatigue are presumed due to perturbations of the relaxation/filling phase (diastole) of the cardiac cycle, which has been termed diastolic dysfunction. In fact, diastole is mechanistically complex and involves LV pressure decay (relaxation), chamber compliance and atrial contractile function. LV end-diastolic volume, which represents fiber stretch, governs LV contractile function and stroke volume via the Frank-Starling mechanism. End-diastolic fiber stretch is, in turn, dependent on late diastolic filling due ...
Hall, Cynthia Ann, The role of left atrial chamber size as assessed by echocardiography in determining thromboembolic complications of atrial fibrillation (1986). Yale Medicine Thesis Digital Library. 2684 ...
We are aware that the COVID-19 pandemic is having an unprecedented impact on researchers worldwide. The Editors of all The Company of Biologists journals have been considering ways in which we can alleviate concerns that members of our community may have around publishing activities during this time. Read about the actions we are taking at this time.. Please dont hesitate to contact the Editorial Office if you have any questions or concerns.. ...
Acadia Pharmaceuticals treatment for Parkinsons disease-related psychosis failed a Phase 3 trial that was studying use of the drug for schizophrenia
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In the uncommon anatomic variation of the course of the RCA, the mid and distal segments course through the atrial chamber. The clinical consequence is minimal except during any procedure where a wire is passed into or through the right atrium, w...
An implantable cardiac stimulation device and associated method to verify capture of a stimulated atrial site by detecting a conducted depolarization at another atrial site or in the opposite atrial chamber. A signal received during an atrial capture detection window is compared to a depolarization signal threshold or to a depolarization signal template in order to verify detection of a conducted depolarization signal as evidence of capture at the stimulated site. By sensing depolarization signal away from the stimulated site, the negative effects of lead polarization normally encountered when detecting an evoked response are avoided.
Merck said first-quarter profit rose on gains from a deal with longtime partner AstraZeneca, although the companys sales rose only 1 percent as negative results of a clinical trial slowed growth of its Vytorin and Zetia cholesterol drugs.
TY - JOUR. T1 - Human eHAND, but not dHAND, is down-regulated in cardiomyopathies. AU - Natarajan, Aruna. AU - Yamagishi, Hiroyuki. AU - Ahmad, Ferhaan. AU - Li, Duanxiang. AU - Roberts, Robert. AU - Matsuoka, Rumiko. AU - Hill, Sandra. AU - Srivastava, Deepak. PY - 2001. Y1 - 2001. N2 - The progression of cardiomyopathy to congestive heart failure is often associated with the expression of fetal cardiac-specific genes. In mice, the basic helix-loop-helix transcription factors, dHAND and eHAND, are expressed in a cardiac chamber-specific fashion and are essential for fetal cardiac development, but are down-regulated in the adult. Their expression in specific chambers of healthy and diseased human hearts has not been studied previously. Human dHAND and eHAND were mapped to human chromosomes 4q33 and 5q33, respectively, by fluorescent in situ hybridization, RNA from the four chambers of healthy human adult hearts, and from hearts of patients with several forms of cardiomyopathy, was obtained and ...
The search for the heart fields dates to mapping studies carried out on embryos in the 1940s was the beginning of identifying lateral plate mesoderm that gives rise to cardiogenic cells and has the potential to for myocardium [7]. The heart field regions lie laterally to the primitive streak, with the subpharyngeal mesodermal progenitor cells of the secondary heart field (SHF) located medially and ventrally to the primary heart field (PHF) cells that give rise to the primary linear heart tube. The PHF and the SHF are adjacent within the heart field region of the lateral plate mesoderm and cardiac crescent (refer to student figure 2). It is understood that in the pharyngeal mesoderm the cardiac regions are prepatterned in the progenitor cell population [8], hence being termed specified but undifferentiated. It is the patterning of cells within the soon to become myocardium, that is responsible differentiation into chamber-specific myocytes (atrial and ventricular) and conduction cells [9]. ...
The basic technique for IART mapping involves collection of electrograms from one or both atria during sustained tachycardia, incorporating enough data points to establish the activation sequence over the entirety of the IART cycle length. This pattern can then be viewed in the context of surgical scars and natural conduction barriers to arrive at a rational model for macroreentry. Entrainment pacing with analysis of postpacing intervals can be used to decipher complex circuits when uncertainty exists.56. Ablation can be attempted once the route for propagation has been established with reasonable certainty, but even when tachycardia location is firm, the task of creating an effective line of conduction block in CHD patients with thickened and dilated atrial chambers is demanding. Quite often, the target area is wider than the average lesion dimension of a single RF application, so multiple contiguous lesions have to be placed to establish permanent block in the target area. This leaves open the ...
The anterior mitral leaflet (aml) is well seen, as well as the left ventricular and atrial chambers. The inferobasal portion of the left ventricle is particularly well seen in this view - perhaps the major justification for this particular part of the TOE examination! (The inferobasal part is that part of the LV in the upper portion of the image, close to the probe). Remember that in the visible human from which these anatomical sections were taken, the left side is particularly poorly filled, and thus the LV cavity appears much plumper in the echo image. Compare the above with the two-chamber mid-oesophageal view. ...
Intramuscular triacylglycerols measured by Oil Red O staining combined with an immunofluorescence staining against slow myosin heavy chain (sMHC), to determine
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Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults [document url="http://asecho.org/wordpress/wp-content/uploads/201...