Adenoviruses (members of the family Adenoviridae) are medium-sized (90-100 nm), nonenveloped (without an outer lipid bilayer) viruses with an icosahedral nucleocapsid containing a double stranded DNA genome. Their name derives from their initial isolation from human adenoids in 1953. They have a broad range of vertebrate hosts; in humans, more than 50 distinct adenoviral serotypes have been found to cause a wide range of illnesses, from mild respiratory infections in young children (known as the common cold) to life-threatening multi-organ disease in people with a weakened immune system. Group: dsDNA Order: Unassigned Family: Adenoviridae Genus: Atadenovirus Bovine atadenovirus D Duck atadenovirus A Ovine atadenovirus D Possum atadenovirus A Snake atadenovirus A Genus: Aviadenovirus Falcon aviadenovirus A Fowl aviadenovirus A Fowl aviadenovirus B Fowl aviadenovirus C Fowl aviadenovirus D Fowl aviadenovirus E Goose aviadenovirus A Turkey aviadenovirus B Genus: Ichtadenovirus Sturgeon ...
Mastadenovirus is a genus of viruses, in the family Adenoviridae. Human, mammals, and vertebrates serve as natural hosts. There are currently 25 species in this genus, including the type species Human mastadenovirus C. Diseases associated with this genus include: very common human infection, estimated to be responsible for between 2% and 5% of all respiratory infections. usually mild respiratory, gastrointestinal and eye infections. serotypes 3, 5 and 7: lower respiratory tract infections. serotypes 8, 19, and 37: epidemic keratoconjunctivitis. serotypes 4 and 7: acute respiratory disease. serotypes 40 and 41: gastroenteritis. serotype 14: can cause potentially fatal adenovirus infections. Canine adenovirus 1 (CAdV-1) can lead to death in puppies, or encephalitis in other carnivore species. Group: dsDNA Order: Unassigned Family: Adenoviridae Genus: Mastadenovirus Bat mastadenovirus A Bat mastadenovirus B Bovine mastadenovirus A Bovine mastadenovirus B Bovine mastadenovirus C Canine ...
Marek, Ana and Kaján, Győző and Kosiol, Carolin and Benkő, Mária and Schachner, Anna and Hess, Michael (2016) Genetic diversity of species Fowl aviadenovirus D and Fowl aviadenovirus E. Journal of General Virology, 97. pp. 2323-2332. ISSN 0022-1317 (print), 1465-2099 (online) Pénzes, Judt J. and Pham, Hanh T. and Benkő, Mária and Tijssen, Peter (2015) Novel parvoviruses in reptiles and genome sequence of a lizard parvovirus shed light on Dependoparvovirus genus evolution. Journal of General Virology, 96 (9). pp. 2569-2579. ISSN 0022-1317 (print), 1465-2099 (online) Pénzes, Judt J. and Menendez-Conejero, R. and Condezo, G.N. and Ball, Ina and Papp, Tibor and Doszpoly, Andor and Paradela, A and Perez-Berna, A.J. and Lopez-Sans, M and Nguyen, T. H. and van Raaij, M.J. and Marschang, R.E. and Harrach, Balázs and Benkő, Mária and San Martin, C (2014) Molecular characterization of a lizard adenovirus reveals the first atadenovirus with two fiber genes and the first adenovirus with either ...
The vast sequence divergence among different virus groups has presented a great challenge to alignment-based analysis of virus phylogeny. Due to the problems caused by the uncertainty in alignment, existing tools for phylogenetic analysis based on multiple alignment could not be directly applied to the whole-genome comparison and phylogenomic studies of viruses. There has been a growing interest in alignment-free methods for phylogenetic analysis using complete genome data. Among the alignment-free methods, a dynamical language (DL) method proposed by our group has successfully been applied to the phylogenetic analysis of bacteria and chloroplast genomes. In this paper, the DL method is used to analyze the whole-proteome phylogeny of 124 large dsDNA viruses and 30 parvoviruses, two data sets with large difference in genome size. The trees from our analyses are in good agreement to the latest classification of large dsDNA viruses and parvoviruses by the International Committee on Taxonomy of Viruses
Human mastadenovirus B ATCC ® VR-718D™ Designation: Genomic DNA from Human mastadenovirus B strain Holden [ATCC ® VR-718™] Application: It is suitable for use in polymerase chain reaction (PCR) for viral gene products and other molecular virology applications. Respiratory research
Bovine adenovirus type 3 (BAdV-3), which is a non-enveloped icosahedral particle with a double-stranded DNA genome of 34,446 base pair, has been developed as a vaccine vector. It belongs to mastadenovirus genus in adenoviridae family. Like other mastadenovirus members, BAdV-3 genome is composed of early, intermediate and late regions. The seven late regions (L1-7) of BAdV-3 genome all belong to one major late transcription unit (MLTU), which is controlled by the major late promoter (MLP). L2 region encodes only one protein V (pV), which is a core protein and functions as a bridge between the viral capsid and DNA genome. It also has been shown to interact with cellular protein p32, which shuttles between nucleus and mitochondria, and redistribute nucleolar proteins B23 and nucleolin. Both of the cellular protein interaction and redistribution suggest that pV may have other functions in viral replication rather than just being a structural protein. Therefore, the objective of this study is to ...
Mastadenovirus (genus), human adenovirus (species). The GMO is a replication incompetent recombinant adenovirus (human serotype 5) containing the human gene for interleukin-12 (referred to as Adv/IL-12) ...
Introduction. According to the International Committee on Taxonomy of Viruses (ICTV), host range specificity, genomic organisation, virion properties, structure, size and serological differences divide the large family of Adenoviridae into four distinct genera (Benkő et al. 2005). At present, these genera areMastadenovirus (infecting mammals), Aviadenovirus (infecting birds), Atadenovirus (named after the bias of their genomes containing high A+T content infecting a broad range of hosts including ruminants, as well as avian, reptilian and marsupial hosts), and Siadenovirus (infects birds and frogs). The fifth suggested genus is called Ichtadenovirus, isolated from fish (Benkő et al. 2005; Kovács et al. 2003).. The genus Aviadenovirus is further divided into eight species: Falcon adenovirus A, Fowl adenovirus(FAdV) A, Fowl adenovirus B, Fowl adenovirus C, Fowl adenovirus D, Fowl adenovirus E, Goose adenovirus A and Turkey adenovirus B. Fowl adenovirus 1 (FAdV-1) belongs to species A and FAdV-5 ...
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Human adenoviruses (HAdVs) cause a wide range of diseases worldwide, including respiratory infections. Studies on HAdV molecular epidemiology are limited in Cameroon. The purpose of this study is to document the different types HAdV circulating in Cameroon in children with acute respiratory infections. Nasopharyngeal swabs were collected from 811 children under 15 years from 2011 to 2014. The HAdV detection was assessed by semi-quantitative generic PCR r-gene®. The HAdV-positive samples were typed by amplification and sequencing of partial hexon gene and a real-time PCR. Demographic data were collected and analyzed. The infection and hospitalization risk factors were assessed thought the Chi-square test. A total of 137/220 HAdV-positive samples were amplified successfully. Six species of HAdV (Mastadenovirus A to F) were detected with B (108/220) and C (47/220) being the predominant strains. Hospitalization and age were significantly associated to HAdV-B and HAdV-C respectively. Phylogenetic analysis
Human adenoviruses are non-enveloped dsDNA viruses of almost 35 kb in size [1]. HAdV can infect a variety of tissues and cause a wide range of complications like gastroenteritis, hepatitis, myocarditis, keratoconjunctivitis and pneumonia [2, 3]. It is contagion in nature which occurs through direct contact or fomites and virus is also resistant to various physical and chemical agents. Children younger than the age of 5 years and immune compromised persons especially the pediatric patients are most susceptible to these viruses. Worldwide 5-7% respiratory tract infections are ascribed by HAdV in pediatric patients [4] and persons of all ages are susceptible to infections caused by these viruses [5].. Seven known Human adenoviruses species from HAdV-A to HAdV-G are constitute of the genus Mastadenovirus in which all the human adenoviruses are categorized and further divided into different strains [6]. Now 67 types of HAdV have been reported [7]. Their number is rapidly increasing due to ...