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In their recent study,3 Dr. Chow and her colleagues set out to localize clusters of apathy symptoms empirically, with actual patients with dementia, to see whether the affective, behavioural, or cognitive apathy symptoms tended to occur together or in isolation, and whether apathy typically co-occurs with other types of behavioural disturbances.. Dr. Chow showed combined data from Baycrest, Sunnybrook [Health Sciences Centre], UC San Francisco, and UCLA, showing results on the Neuropsychiatric Inventory (NPI). On the section of the NPI that deals with apathy, patients are questioned on spontaneous activity, spontaneity in conversation, participation in former activities, participation in former chores, demonstration of interest in others, investment in friends and family, and degree of affection.. Results showed that, for those with either FTD or Dementia of Alzheimers type (DAT), the most common type of apathy, when present, was a decrease in spontaneous activity. Comparing the percentage of ...
In their recent study,3 Dr. Chow and her colleagues set out to localize clusters of apathy symptoms empirically, with actual patients with dementia, to see whether the affective, behavioural, or cognitive apathy symptoms tended to occur together or in isolation, and whether apathy typically co-occurs with other types of behavioural disturbances.. Dr. Chow showed combined data from Baycrest, Sunnybrook [Health Sciences Centre], UC San Francisco, and UCLA, showing results on the Neuropsychiatric Inventory (NPI). On the section of the NPI that deals with apathy, patients are questioned on spontaneous activity, spontaneity in conversation, participation in former activities, participation in former chores, demonstration of interest in others, investment in friends and family, and degree of affection.. Results showed that, for those with either FTD or Dementia of Alzheimers type (DAT), the most common type of apathy, when present, was a decrease in spontaneous activity. Comparing the percentage of ...
ADMET 2 will examine in a masked, randomized trial the efficacy of methylphenidate for the treatment of clinically significant apathy in participants with Alzheimers dementia. Efficacy will be assessed as the change in Neuropsychiatric Inventory Apathy subscale (NPI apathy) from baseline to 6 months and score on the Alzheimers Disease Cooperative Study - Clinical Global Impression of Change (CGIC) scale at 6 months.. ADMET 2 will also examine the safety of methylphenidate for the treatment of clinically significant apathy in participants with Alzheimers disease by measuring vital signs, electrolyte panels, adverse event reports, and electrocardiograms. Safety will also be measured by examining neuropsychiatric symptoms other than apathy using the Neuropsychiatric Inventory (NPI).. Changes from baseline to 6 months in other neuropsychological assessments as measured using the Dementia Apathy Interview and Rating (DAIR) scale will also be assessed.. Cost-effectiveness will be measured by ...
ADMET 2 will examine in a masked, randomized trial the efficacy of methylphenidate for the treatment of clinically significant apathy in participants with Alzheimers dementia. Efficacy will be assessed as the change in Neuropsychiatric Inventory Apathy subscale (NPI apathy) from baseline to 6 months and score on the Alzheimers Disease Cooperative Study - Clinical Global Impression of Change (CGIC) scale at 6 months.. ADMET 2 will also examine the safety of methylphenidate for the treatment of clinically significant apathy in participants with Alzheimers disease by measuring vital signs, electrolyte panels, adverse event reports, and electrocardiograms. Safety will also be measured by examining neuropsychiatric symptoms other than apathy using the Neuropsychiatric Inventory (NPI).. Changes from baseline to 6 months in other neuropsychological assessments as measured using the Dementia Apathy Interview and Rating (DAIR) scale will also be assessed.. Cost-effectiveness will be measured by ...
TY - JOUR. T1 - Apathy is associated with ventral striatum volume in schizophrenia spectrum disorder. AU - Roth, Robert M.. AU - Garlinghouse, Matthew A.. AU - Flashman, Laura A.. AU - Koven, Nancy S.. AU - Cara Pendergrass, J.. AU - Ford, James C.. AU - McAllister, Thomas W.. AU - Saykin, Andrew. PY - 2016. Y1 - 2016. N2 - Apathy is prevalent in schizophrenia, but its etiology has received little investigation. The ventral striatum (VS), a key brain region involved in motivated behavior, has been implicated in studies of apathy. We therefore evaluated whether apathy is associated with volume of the VS on MRI in 23 patients with schizophrenia using voxel-based morphometry. Results indicated that greater self-reported apathy severity was associated with smaller volume of the right VS even when controlling for age, gender, depression, and total gray matter volume. The finding suggests that apathy is related to abnormality of brain circuitry subserving motivated behavior in patients with ...
OBJECTIVES: Apathy has been reported as the most prevalent behavioural symptom experienced in Alzheimers disease (AD), associated with greater functional decline and caregiver distress. The aim of the current study was to investigate structural correlates of apathy in AD using magnetic resonance imaging (MRI) regional volume and regional cortical thickness measures. METHODS: Semi-structured interviews were conducted with 111 AD patients and their caregivers as part of the European multi-centre study AddNeuroMed. Apathy was measured using the apathy domain of the Neuropsychiatric Inventory (NPI). All AD patients were scanned using a 1.5T MRI scanner and the images analysed using an automated analysis pipeline. RESULTS: We found apathy to be the most prevalent neuropsychiatric symptom occurring in 57% of patients. Apathetic patients had significantly greater cortical thinning in left caudal anterior cingulate cortex (ACC) and left lateral orbitofrontal cortex (OFC), as well as left superior and
OBJECTIVES: Apathy has been reported as the most prevalent behavioural symptom experienced in Alzheimers disease (AD), associated with greater functional decline and caregiver distress. The aim of the current study was to investigate structural correlates of apathy in AD using magnetic resonance imaging (MRI) regional volume and regional cortical thickness measures. METHODS: Semi-structured interviews were conducted with 111 AD patients and their caregivers as part of the European multi-centre study AddNeuroMed. Apathy was measured using the apathy domain of the Neuropsychiatric Inventory (NPI). All AD patients were scanned using a 1.5T MRI scanner and the images analysed using an automated analysis pipeline. RESULTS: We found apathy to be the most prevalent neuropsychiatric symptom occurring in 57% of patients. Apathetic patients had significantly greater cortical thinning in left caudal anterior cingulate cortex (ACC) and left lateral orbitofrontal cortex (OFC), as well as left superior and
Background: Geriatric depression with subjective memory complaints increases the risk for Alzheimers Disease. Memantine, a neuroprotective drug, can improve depression and help prevent cognitive decline. In our 6-months clinical trial, escitalopram/memantine (ESC/MEM) improved mood and cognition compared to escitalopram/placebo treatment (ESC/PBO; NCT01902004). In this report, we investigated whether baseline brain white matter integrity in fronto-limbic-striatal tracts can predict clinical outcomes using fractional anisotropy (FA).Methods: Thirty-eight older depressed adults (mean age = 70.6, SD = 7.2) were randomized to ESC/MEM or ESC/PBO and underwent diffusion-weighted imaging (DWI) at 3 Tesla at baseline. Mood was assessed using the Hamilton Depression Rating Scale (HAMD), apathy using the Apathy Evaluation Scale (AES) and anxiety using the Hamilton Anxiety Scale (HAMA) at baseline and 6-months follow-up. FA was extracted from seven tracts of interest (six in each hemisphere and one commissural
For the study, researchers examined 79 adolescents ages 14 to 18, who were classified as recent regular cannabis users (36) or light users (43). Frequency and amount of substance use were assessed across participants lifetime and during the past 30 days, and motivation was measured through the Apathy Evaluation Scale and Motivation and Engagement Scale. To examine associations between cannabis use (CU) and motivation indices, researchers conducted a series of two-step hierarchical multiple regressions.. After controlling for confounds, no significant differences were observed between regular and light users on any motivation index, states the study. Similarly, no associations between motivation and lifetime or past 30-day CU amount were observed.. The study concludes by stating; Our findings do not support a link between reduced motivation and CU among adolescents after controlling for relevant confounds.. The full study, conducted by researchers at Florida International University, ...
January 29, 2010. Most people think of memory loss when they think of Alzheimers. But the disease can cause a wide range of behavioral and personality changes as well. One of the most common is apathy, or loss of motivation, and the condition seems to have a biological basis. Using brain scans, researchers in Sweden report that changes in the brains white matter are a common feature in apathetic patients who have Alzheimers or other forms of dementia.. Apathy is one of the most common psychological problems associated with dementia. Just over half of all people with Alzheimers are emotionally blunted and lack motivation and initiative. As the disease worsens, apathy often grows worse.. Studies suggest there is a common biological reason behind apathy, irrespective of whether a person has Alzheimers or other forms of dementia. The changes occurred in areas deep in the brain that are connected to the brains frontal lobes, which are critical for taking initiatives and the ability to ...
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Apathy. It has become a major issue for so many people today. While many people associate apathy with a lack of passion or motivation, it is technically defined as the absence of emotion.
Apathy Just Begun lyrics & video : [Funkmaster flex sample] [Celph Titled] Yo what the f**k are yall thinkin Lettin Apathy get on the mic Thats like unleashing a f**king atom...
BACKGROUND: Alzheimers disease (AD) is characterized not only by cognitive and functional decline, but also often by the presence of neuropsychiatric symptoms. Apathy, which can be defined as a lack of motivation, is one of the most prevalent neuropsychiatric symptoms in AD and typically leads to a worse quality of life and greater burden for caregivers. Treatment options for apathy in AD are limited, but studies have examined the use of the amphetamine, methylphenidate. The Apathy in Dementia Methylphenidate Trial (ADMET) found that treatment of apathy in AD with methylphenidate was associated with significant improvement in apathy in two of three outcome measures, some evidence of improvement in global cognition, and minimal adverse events ...
A. H. Craig, J. L. Cummings, L. A. Fairbanks, L. Itti, B. L. Miller, J. Li, I. Mena, Cerebral blood flow correlates of apathy in Alzheimer disease, Archives of Neurology, Vol. 53, No. 11, pp. 1116-20, Nov 1996. [1998 impact factor: 3.375] (Cited by 231). Abstract: BACKGROUND: Apathy is a pervasive noncognitive neuropsychiatric disturbance in Alzheimer disease, which causes significant caregiver distress. The neuroanatomical substrate of apathy is not well understood. OBJECTIVE: To study the relationship between regional cerebral blood flow and the presence and severity of the personality disturbance, apathy, in individuals with Alzheimer disease. DESIGN: Analysis of the relationship between regional cerebral blood flow as measured by single photon emission computed tomography and severity of apathy as measured by the Neuropsychiatric Inventory using an analysis of variance design. We examined regional cerebral perfusion alterations as measured by xenon 133Xecalibrated technetium Tc 99m ...
k4140] High doses of dopamine are usually needed to help patients suffering from apathy. In one study, seven out of eight patients who became depressed following liver transplants and were given methylphenidate, or Ritalin, a drug that elevates dopamine levels, showed improved motivation in pursuing their rehabilitation regimens and less social withdrawal and apathy than they exhibited before taking the drug. For apathy patients, drugs are not the final cure. They also need assistance in practicing techniques to help themselves. Education of the family is an important job for the therapist, too. Treatment of apathy raises some complex human rights issues, because these patients may be competent enough to make some decisions but not others. They are also prone to anxiety, which must be relieved so that they will consider options and get involved with life again. Treating apathy is also important in depressed patients. Drugs can be used to bring about rapid improvement at an early stage. Since ...
National Institutes of Health Funding to Support Ongoing Advancement of Innovative Treatments in Preventing and Treating Alzheimers Disease and Alzheimers Disease-Related DementiasLOS ANGELES, Aug. 05, 2021 (GLOBE NEWSWIRE) -- Praxis is proud to announce to be the recipient of a Fast-Track SBIR award to develop treatment for apathy in Alzheimers Disease. The award, in its second of three years and expected to total $2.9 million, will support the IND-enabling work to advance the Companys lead
TY - JOUR. T1 - Apathy is associated with activities of daily living ability in Parkinsons disease. AU - Laatu, S. AU - Karrasch, Mira. AU - Martikainen, K. AU - Marttila, R. PY - 2013. Y1 - 2013. M3 - Artikel. VL - 35. SP - 249. EP - 255. JO - Dementia and Geriatric Cognitive Disorders. JF - Dementia and Geriatric Cognitive Disorders. SN - 1420-8008. IS - 5. ER - ...
TY - JOUR. T1 - Apathy is associated with activities of daily living ability in Parkinsons disease. AU - Laatu, S. AU - Karrasch, Mira. AU - Martikainen, K. AU - Marttila, R. PY - 2013. Y1 - 2013. M3 - Artikel. VL - 35. SP - 249. EP - 255. JO - Dementia and Geriatric Cognitive Disorders. JF - Dementia and Geriatric Cognitive Disorders. SN - 1420-8008. IS - 5. ER - ...
Apathy is a debilitating and under-recognized condition that has a significant impact in many neurodegenerative disorders. In Parkinsons disease, it is now known to contribute to worse outcomes and a reduced quality of life for patients and carers, adding to health costs and extending disease burde …
Apathy is a non-motor symptom of Parkinson s disease that is sometimes misinterpreted as laziness, poor initiative or depression.
Author: Frisch, Stefan et al.; Genre: Journal Article; Published in Print: 2017-12; Title: Apathy and cognitive deficits in patients with transient global ischemia after cardiac arrest
(KudoZ) French to English translation of L ACEDIE: acedia (A mental disorder characterized by apathy and melancholia) [MEDICAL - Medical (general) (Medical)].
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Abstract: Objectives: People with Huntingtons disease (HD) experience poor social quality of life, relationship breakdown, and social withdrawal, which are mediated to some extent by socially debilitating neuropsychiatric symptoms, such as apathy and disinhibition. Social cognitive symptoms, such as impaired emotion recognition, also occur in HD, however, the extent of their association with these socially debilitating neuropsychiatric symptoms is unknown. Our study examined the relationship between emotion recognition and symptom ratings of apathy and disinhibition in HD. Methods: Thirty-two people with premanifest or symptomatic-HD completed Part 1 of The Awareness of Social Inference Test (TASIT), which is a facial emotion recognition task. In addition, we obtained severity ratings for apathy and disinhibition on the Frontal Systems Behavior Scale (FrSBe) from a close family member. Our analyses used motor symptom severity as a proxy for disease progression. Results: Emotion recognition ...
IUPsyS is psychologys international organization in Official Relations with the WHO and these were renewed in January 2014. In this capacity IUPsyS was appointed to the International Advisory Group (IAG) for the Revision of ICD-10 Mental and Behavioural Disorders in 2006 and Secretary General, Dr Ann Watts, currently represents the Union on the IAG. Psychologys contributions to the development of ICD-11 remain a key IUPsyS strategic priority. To support this important initiative the IUPsyS has seconded psychologist Dr Geoff Reed to the WHO to serve as Senior Project Officer for the Mental and Behavioural Disorders component of the ICD-10 revision. In this capacity Dr Reed reports to the Director of the WHO Department of Mental Health and Substance Abuse, Dr Shekhar Saxeena, and Dr Pierre Ritchie, Co-Main Representative (Psychology) to WHO. Dr Reeds work at WHO has been suported by major grants from the American Psychological Association (APA) to IUPsyS (2008-12; 2013-14;2015-6). The Agreement ...
Psychometric support was found for all 3 versions of the BFNE, although the longer 12-item BFNE-II did not improve measurement compared to the shorter 8-item versions (BFNE-S and BFNE-8). Of these 2, the BFNE-S has been more widely studied, with strong validity data in a greater number of population …
This study examined the brain bases of early human social cognitive abilities. Specifically, we investigated whether cortical regions implicated in adults perception of facial communication signals are functionally active in early human development. Four-month-old infants watched two kinds of dynamic scenarios in which a face either established mutual gaze or averted its gaze, both of which were followed by an eyebrow raise with accompanying smile. Haemodynamic responses were measured by near-infrared spectroscopy, permitting spatial localization of brain activation (experiment 1), and gamma-band oscillatory brain activity was analysed from electroencephalography to provide temporal information about the underlying cortical processes (experiment 2). The results revealed that perceiving facial communication signals activates areas in the infant temporal and prefrontal cortex that correspond to the brain regions implicated in these processes in adults. In addition, mutual gaze itself, and the ...
Objective: Aging societies will bring an increase in the number of long-term care patients with mental-physical multimorbidity (MPM). This paper aimed to describe the natural course of neuropsychiatric symptoms (NPS) in patients with MPM in the first 8 months after admission to a geronto-psychiatric nursing home (GP-NH) unit. Methods: Longitudinal cohort study among 63 patients with MPM no dementia living in 17 GP-NH units across the Netherlands. Data collection consisted of chart review, semi-structured interviews, and brief neuropsychological testing, among which our primary outcome measure the Neuropsychiatric Inventory (NPI). Descriptive and bivariate analyses were conducted. Results: Our study showed a significant increase of the NPI total score (from 25.3 to 29.3, p = 0.045), and the total scores of a NPI hyperactivity cluster (from 9.7 to 11.8, p = 0.039), and a NPI mood/apathy cluster (from 7.7 to 10.1, p = 0.008). Just over 95% had any clinically relevant symptom at baseline and/or six ...
The goal of this research was to evaluate the impact of ACES (Accompagnement Collaborative des Enseignants du Secondaire), a training program for high school teachers aimed at facilitating the educational integration of students with special needs. Offered individually or in groups, the program was well received by all stakeholders and had a positive impact on teachers, students and the classroom climate. The program positively influenced teachers attitudes towards their students, their understanding of behavioural disorders, their use of positive and proactive intervention strategies, and the student-teacher relationship.. Teachers who took part in the program had a significantly lower level of teaching stress than those in the control groups. While little difference was observed between the two versions of the program, the group training was more popular with all parties concerned.. ...
Psychiatric and Behavioural Disorders in Intellectual and Developmental Disabilities General Medical Ebook by Nick Bouras, Geraldine Holt,
A number of biological markers have been implicated in late life depression with inconsistent results. The present study examined the relationship between several serum based biomarkers and symptoms of depression in a sample of elderly women with AD or cognitively intact. Methods 171 females (58 with AD and 113 cognitively intact) were recruited from the Longitudinal Research Cohort of the Texas Alzheimers Research and Consortium (TARC). Stepwise regressions were conducted with GDS total and subscales and a panel of biomarkers (CRP, IL-10, IL-1α, TNF-α, ICAM-1, BDNF, and MIF). ApoE4 status was coded (carrier or non-carrier), and the results were analyzed by cognitive status (AD or controls). Results: None of the biomarkers significantly predicted total GDS score for AD cases, controls or sample as a whole. For the Controls, ICAM significantly predicted Dysphoria and level of Apathy. Among AD patients, MIF, ICAM, and CRP, were significantly associated with Apathy. MIF and ICAM were inversely
This mutation was identified in a Spanish family with AD that progressed relatively slowly, with a wide range of ages of onset (Lladó et al., 2010). A total of six family members were affected, with ages of onset ranging from the fifth to eighth decade of life. The mutation was found in all three affected members who were tested, and was absent from 121 controls and 163 AD patients.. The proband was a man who developed cognitive decline with behavioral abnormalities at age 57. His behavioral symptoms included apathy, irritability, social withdrawal, and, ultimately, marked aggressiveness for which he was institutionalized at age 70. Another family member carrying the mutation also initially presented with apathy and irritability, and subsequently became aggressive, but her symptoms started earlier, at age 42. Surprisingly, a third mutation carrier in the same family presented with typical AD at age 71. This is in contrast to the complete penetrance of PSEN1 mutations usually seen by age 65. All ...
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Psychic akinesia has been described in patients that are fully responsive, but with no display of goal directed activities. It is characteristic of patients with psychic akinesia to correctly perform most of their daily activities, but only after strong stimulation.42 A similar syndrome was labelled the autoactivation deficit by Laplane and Dubois, and was defined as a deficit in spontaneous activation of mental processing, observed in behavioural, cognitive or affective domains, which can be totally reversed by external stimulation that activates normal patterns of response.43 The authors listed the following symptoms of autoactivation deficit: (1) inertia (defined as the tendency to stay immobile for long periods and taking no initiatives), (2) mental emptiness (defined as lack of thoughts and no projections onto the future), (3) repetitive and stereotyped activities, (4) flat affect and (5) blunted emotional responses. Full reversal of the negative state on external stimulation was ...
Apathy is a subject near and dear to my own heart. I have shared before how hard Ohio winters are on me physically and mentally. I have come to realize that I do best when I fight back with a variety of tools such as happy lights, supplementation, outdoor time, exercise, and healthy foods. The kink in the otherwise perfect plan though can be aptly named, apathy. You may know what you need to do but you just cant work up the enthusiasm or energy to do it. You become indifferent to your … [Read more...] ...
Reduced alertness, fatigue, apathy, insomnia are often lumped together. As a rule in older folks, alertness aint what it used to be. [9] The exceptions are a wonderful thing to behold. I am surprised at finding a number of people as young as being in their fifties, who share with older folks the poor recall of names. If you think of the brain being like a computer, it is if something happened to the address book. You cant put names to the faces. Mental stress is a big contributor to the development of feeling fatigued. Multitasking is a problem. Not being able to breeze through tasks, as one did in mid-life, can prove very frustrating and stressful. Realizing that one person has little impact on the worlds problems, leads to apathy or to continue seeking solutions when in the twilight zone of sleep. Dry skin: A universal problem in older folks -- made worse from exposure to dry inside, winter air. [10] Moisturizing lotions seem to be the only remedy, but even with their use, break-through ...
What up, my punky little peanuts? This is the last installment of our three-part intro to Dead Broke Rekerds. So we have a whole other. Read more ...
The markets drift steadily higher as the delta variant thing seems like its decelerating, things are quiet on the monetary policy front and Bidens infrastructure bill advances from the Senate to the House. Earnings have been incredible across the board, and not just compared with the same quarter last year. On an absolute basis companies are reporting record high profits, cash balances, financial flexibility, consumer demand for their products and services, etc. Bank accounts are flush, brokerage accounts are spilling over with gains, 401(k) retirement plan assets are soaring and both consumers and businesses are making new investments for the future.. And its 90 degrees and sunny from coast to coast.. So, of course, were in an environment in which volatility has declined back to pre-pandemic levels and less attention is being paid to the stock market these days. Certainly nowhere near what we were experiencing a year ago. People I know in the financial media business are way down in traffic ...
The opposite of Apathy is Love. Last Saturday my husband and I joined four other couples for a dinner club and the discussion around the table was anything but apathetic. Jokes about the election year and the wild ride ahead for us Americans mingled with updates on our families and local parishes. Wine glasses clinked and Italian sauced plates scraped clean as five women and five men tried to predict how the public would soon vote and who our next president will be. The famous quote, Never talk politics or religion in polite company was disregarded and I believe with good reason. As Christians we care about our country, families and our churches and to sit back and do nothing would be considered apathetic. And apathy is the opposite of love.. Later in the evening when we resumed to the living room, the hostess presented our group with a challenge. Before Jesus ascended up to Heaven, He told his disciples to wait until the Holy Spirit has come down in power to help them. So for Ten days the ...
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JP is so right!](http://confusedofcalcutta.com/2007/09/06/wondering-about-alarmapathy/). , I have lost count of the number of times Ive sat in a car whose dashboard is littered with various alerts and alarms. I have lost count of the number of times Ive seen kitchen appliances whose control panels are flashing whatever they flash. I have lost count of the number of times Ive seen televisions and video recorders and DVD players and radios and computers with bits and bobs flashing away merrily.. , […]. , Apathy sets in when we have too many alarms, too many meaningless alarms. Alarms should be risk sensors that help us make decisions that carry risk. Instead, we may be moving towards a world where nanny-state numbness is moving on to devices, and as a result apathy will increase.. , You know what I mean. You know that we live in a world where a talking bag of peanuts is no longer science fiction, where the bag says Warning: The bag you are opening contains nuts. Where you cant take ...
In the last 4 years of funding we have defined the conditions under which T cells obviate the requirement for costimulatory signaling during activation, and med...
But Gorakhpur is not the first such incident, and unless there is a deep dive to find and isolate the root cause, it wont be the last either
I dont know how else to tell you this but I was rocking my piss shirt up at McyDs and the entire shift fell out to crack up. 6 dudes came out the back. thought it might give you a chuckle. ...
Dozens of US AIDS activists demonstrated at a world AIDS conference here Wednesday calling on White House candidates to commit to HIV prevention, as experts warned of emerging US public
Home care. A social network of friends and family may be of help. They can revive your interest in life and your environment. The services of mental health professionals are also indispensable. With their help, you can see life from a brighter perspective. Combining medications with therapy will have a more potent effect compared to either treatment on its own.. Future treatments. Research is ongoing for treatment of chronic apathy. A possible treatment would be cranial electrotherapy stimulation. This can help in treatment of traumatic brain injury affecting the frontal lobe. The treatment involves the application of a low-voltage electric current to the forehead. It is a painless treatment. Cognitive stimulation therapy is another form of treatment. It is used mainly for treating Alzheimer patients. Cognitive stimulation therapy involves taking part in group activities for the purpose of stimulating brain waves.. ...
At the recent Patient Advocacy Conference I attended, I spoke with a community member. Weve previously met but Ive talked more with his family members. Hes always seemed to be rather shy.. He asked me how I motivate myself. Ive been asked this before. Many people with myotonic dystrophy experience both overwhelming physical fatigue as well as extreme apathy. The first time I attended the annual patient conference I participated in a panel discussion. Afterwards I had someone approach me with utter disbelief that I had the disease. Even though I appeared to be similar in age to her daughter, I appeared to function like a normal person.. The more you learn about the disease, the more you realize the diversity of symptoms and severity. Im sure there are many additional factors the research community doesnt take into account, i.e. my self-care routines are like a full-time job.. But getting back to this young man (age is relative and hes ~20 years my junior) and his question. There are ...
Recent events in the nation, perhaps most notably the We March protest that took place last week, showed that The Bahamas has begun to shake off the veil of apathy that we have slumbered under for what feels like too long. This year has been a belter for politics and people of all beliefs making their feelings known - for better or for worse. And, as art so often engages with the state of society, so it is that many of the submissions for the 8th National Exhibition (NE8) at the National Art Gallery of The Bahamas (NAGB) were brash, bold, opinionated, and deeply political; reflecting how strongly so many of us feel after the various events of 2016.
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Learn when youre using empathy vs. sympathy vs. apathy with Grammar Rules from the Writers Digest editors, including their differences and when they might overlap.
Caregiver burden is high among caregivers of PD patients (CPD). Neuropsychiatric symptoms are leading contributors to CPD burden, but whether different symptoms differentially impact domains of caregiver burden is not known. Our objective was to examine which neuropsychiatric symptoms and demographic factors contribute to different domains of caregiver burden in PD.This was a cross-sectional online survey study. Participants were recruited from the Fox Insight (FI) study and were eligible if they identified themselves as a CPD. The primary outcome was the Caregiver Burden Inventory (CBI) total score and its 5 sub-domain scores. The Neuropsychiatric Inventory Questionnaire (NPI-Q) assessed caregiver-reported neuropsychiatric symptoms in the care recipient. Multivariable linear regression models were used to characterize the associations between NPI-Q symptom severity scores and CBI scores. Covariates were caregiver age, sex, education, and caregiving duration.The sample consisted of 450 CPD, mean ...
University of Southern California DAILY @ TROJAN VOL. LXII NO. 89 LOS ANGELES, CALIFORNIA TUESDAY, MARCH 16, 1971 MARGARET MEAD Media causes apathy-Mead By JAN EDWARDS The media see campuses as dens of apathy. In fact, they bring about that state by a sort of cause-and-effect relationship. This is the observation of Margaret Mead, anthropologist and author, who said. The media say the campuses are calm, and in general the campuses are complying. At noon yesterday in Bovard Auditorium. Dr. Mead spoke to a near-capacity audience. Reviewing the past few years, she found you either have a bust or you have apathy. If youre not having a bust, then youre having apathy. But the campus image in the eye of the community is of marginal importance. she observed. The image students have of themselves is more important than the image that the media give to students. Students have been discouraged about the chances of accomplishing something. Dr. Mead believes that if an organized few are motivated ...
wide download the icd 10 classification of mental and behavioural disorders clinical descriptions and diagnostic: How to like properties with Performance? As such the genealogy is to interrogate Effects for a subject community on a repeated for gossip. It includes extensively other how field were in social consultant signals from joint Studies of sign, nor serves it are how to support it nt.
Gwyn M. Vernon, M.S.N., R.N., C.R.N.P., is co-founder and national director of The Edmond J. Safra Visiting Nurse Faculty Program at the Parkinsons Foundation.. PLEASE NOTE: This web seminar is being hosted by the Parkinsons Foundation, and registration will be handled through their website, www.pdf.org.. *This web seminar is approved for AoTA contact hours in addition to CEUs approved for all ASA web seminars. Questions about registration? Call the Parkinsons Foundation at 800-457-6676.. Questions about CEUs? Call ASA at 415-974-9628.. Have technical issues? Call NetBriefings at 866-225-1532.. ...
I'm very interested to see how the 2008 presidential election affects the motivation levels of students this year. As this article in The Washington Post talks about, the 18-24 age group is notorious for being politically apathetic, particularly those who haven't gone to college, but some are hopeful that that might change. I know this is an issue that doesn't directly affect most high school students, since only a small percentage of them can participate in the voting process, but I do think a presidential election is one of the most exciting things that happens in this country, and even...
Groups consisting each of three males and three females received two i.p. injections of 2500 mg/kg separated by 24 h using an application volume of 10 ml/kg . In addition, two males were treated with an application volume of 20 ml/kg.Symptoms were recorded for up to 48 h (for males: apathy, roughened fur, emaciation, loss of weight, sunken flanks, spasm, difficulty in breathing, eyelids stuck together, slitted eyes, closed eyes, lachrymation, white tears and diarhoea; for females: apathy, roughened fur, emaciation, loss of weight, sunken flanks, spasm, shivering, slitted eyes, closed eyes) None of the animals died. Due to the results it was concluded, that there were no substantial differences between sexes. Therefore, no females were used in the definite study ...
Its a work that questions the foundation of Frederiksens upbringing, one in which his left-leaning parents assured him there was a social order in place that caught the disaffected and prevented people from falling through the cracks. Its a world that Frederiksen isnt convinced exists, as Melbournes housing crisis worsens and the citys homeless population grows. Its a social order that the plays protagonist Miss Shepherd certainly wasnt privy to.. Frederiksen plays Alan Bennett 1, while his former co-star in Matilda, James Millar, plays his characters subconscious, Alan Bennett 2. I love that device Frederiksen says. Its so clever because we all have that internal dialogue, and Im guilty of being like Alan Bennett 1, constantly trying to please people…often to my own detriment.. Despite the challenges both Bennett and Shepherd encounter in this story, Frederiksen believes it is ultimately a tale of friendship, acceptance and, where possible, of not letting people fall through ...
This week on Slate I read a controversial piece: American Jews Are Secular, Intermarried, and Assimilated: Great News! which was written about the recent Pew study on American Jews. The author, Gabriel Roth, tells American Jewry to embrace their secular, intermarried selves and that unless theyre Orthodox and believe, theres no reason to keep this race purity going on. He explains that other than Orthodox Jews, Jews will stop existing soon, and thats a good thing. (Oy!) Roth writes:. And as an intermarried Jewish nonbeliever, I think its time we anxious Jews stopped worrying and learned to love our assimilated condition-even if it means that our children call themselves half-Jewish and our grandchildren dont consider themselves Jews at all. Im not talking, here, to religious Jews, because their position is unarguable: If you believe that Jewish traditions are part of a covenant with God, of course you want your children to continue them.. Roth and I both agree that staying Jewish for ...
ally sleep has been one of the hardest things to study, but some recent studies using a PET scan and a tagged amino acid may give us some clues as to why we need to sleep. One of the theories is that we need sleep to repair proteins in the cells of the brain, which cant happen while we are awake because the brain is too busy and has too many processes happening. During a normal day while we are awake we accumulate adenosine in our brain, which signals our bodies to sleep. Sleep would eliminate the adenosine and produce more proteins for repair of the brain cells.. Humans have varying levels of sleep, but so do many animals in nature. A normal human gets somewhere between 7 and 8 hours of sleep per night, but an animal such as a lion gets up to 15 hours a day. A elephant on the other hand gets around 4 hours of sleep. One of the theories about this is that predator species can sleep more because they dont generally have many predators, while the prey species get much less sleep so they can ...
ally sleep has been one of the hardest things to study, but some recent studies using a PET scan and a tagged amino acid may give us some clues as to why we need to sleep. One of the theories is that we need sleep to repair proteins in the cells of the brain, which cant happen while we are awake because the brain is too busy and has too many processes happening. During a normal day while we are awake we accumulate adenosine in our brain, which signals our bodies to sleep. Sleep would eliminate the adenosine and produce more proteins for repair of the brain cells.. Humans have varying levels of sleep, but so do many animals in nature. A normal human gets somewhere between 7 and 8 hours of sleep per night, but an animal such as a lion gets up to 15 hours a day. A elephant on the other hand gets around 4 hours of sleep. One of the theories about this is that predator species can sleep more because they dont generally have many predators, while the prey species get much less sleep so they can ...
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This is another tragedy that once again reflects the sordid state of hospitals and health care through out India. News of deaths coming from Gorakhpur, Uttar Pradesh is spiralling on a daily basis and that too from just one hospital viz. BRD Hospital, the government-run hospital of the city. It is the only hospital with reasonable faciliities in a 300-km radius and treats encephalitis patients from Gonda, Basti districts, Terai region in Nepal and eastern districts of Bihar. No State can be shown as a model. Like the farmers, the children of the poor in the India are totally neglected. 70 years of our growth of free India is yet to reach them.. A small town named Gonda in UP was at the last position among 434 cities surveyed across the country. It shall also be remembered that Gonda district is among the 10 districts in UP severely affected by Encephalitis. All this means that hygiene is one of the crucial factors in containing encephalitis, and the total failure of administration in this ...
COLLEGE STATION The more you know the less you care at least that seems to be the case with global warming. A telephone survey of 1,093 Americans by two Texas A&M University political scientists and a former colleague indicates that trend, as explained in their recent article in the peer-reviewed journal Risk Analysis. More informed respondents both feel less personally responsible for global warming, and also show less concern for global warming, states the article, titled Personal Efficacy, the Information Environment, and Attitudes toward Global Warming and Climate Change in the USA.. The study showed high levels of confidence in scientists among Americans led to a decreased sense of responsibility for global warming.. The diminished concern and sense of responsibility flies in the face of awareness campaigns about climate change, such as in the movies An Inconvenient Truth and Ice Age: The Meltdown and in the mainstream medias escalating emphasis on the trend.. The research was ...
​When it comes to empathy and sympathy, the problem is that many people cant seem to have either of them until awful shit happens to them as well. Maybe. Too many people are unwilling to make that mental, emotional leap to truly empathize with the unfortunate plight of others. No way we can initiate effective…
While these efforts are of monumental importance, theyre merely Band-Aids covering the wounds of privatization. Even before Trumps ascent to the presidency, the nature of internet oversight was historically laissez-faire, rendering the web an often predatory place ripe for commercial takeover. Governments have failed to regulate the internet as a public utility, furnishing it with unchecked invasive potential. Though the Federal Communications Commission (FCC) technically classified internet as a utility in 2015, it wasnt until late 2016 that the government barred ISPs from collecting such sensitive data as social-security numbers and healthcare information without explicit user consent--a law Americans now wont see come to fruition any time in the near future. The loss of such regulation is foreboding: these requirements were protocol for a communications utility; were a phone company to eavesdrop on a users call without that persons knowledge, it would be violating the law. Now, however, ...
Apathy and fatigue may be caused by thyroid problem or hormone imbalance. Apathy and fatigue in endometriosis is caused by the pressure of coping with any sort of pain that returns relentlessly every month, affecting her physical and emotional state.
The climate is changing. Great Lakes organizations and officials are trying to make sure restoration work is done with this in mind. But climate change remains
A week or so ago, there was a large discussion on QuiltArt.com about copyright. Congress is debating the Orphan Works bill (there is an excellent article on this subject here) and the subject of Flickr.com came up.
As the U.S. military sets out to secure cities including Kandahar, it is relying far more heavily on Afghan forces than at any time in the past nine years, when the American mission focused mainly on defeating the Taliban in the countryside, rather than securing the population. But the Afghan forces are proving poorly equipped and sometimes unmotivated, breeding the same frustration U.S. troops felt in Iraq when they began building up security forces beset by corruption, sectarianism, political meddling and militia infiltration.. ...
It was comfortable in his bed, so he decided to stay there.. It was still comfortable the next day, because it was so soft.. It was still comfortable the next week, because it was so warm.. It was still comfortable the next month, because he couldnt feel anything at all.. ...
The peak of tolerance is most readily achieved by those who are not burdened with convictions, Alexander Chase, Perspectives (1966) Romans 1:26 For this reason God gave them over to dishonorable passions. For their women exchanged the natural sexual relations for unnatural ones, 1:27 and likewise the men also abandoned natural relations with women and were inflamed in their passions for one another
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Neuropsychiatric symptoms (NPS) such as depression, apathy, aggression, and psychosis are now recognized as core features of Alzheimer’s disease (AD), and there is a general consensus that greater symptom severity is predictive of faster cognitive decline, loss of independence, and even shorter survival. Whether these symptoms result from the same pathogenic processes responsible for cognitive decline or have unique etiologies independent of AD-associated neurodegeneration is unclear. Many structural and metabolic features of the AD brain are associated with individual neuropsychiatric symptoms or symptom clusters. In addition, many genes have been identified and confirmed that are associated with symptom risk in a few cases. However, there are no single genes strongly predictive of individual neuropsychiatric syndromes, while functional and structural brain changes unique to specific symptoms may reflect variability in progression of the same pathological processes. Unfortunately, treatment
Background: To study the extent to which neuropsychiatric symptoms (NPS) influence the cognitive and functional decline in frontotemporal degeneration (FTD) and Alzheimers disease (AD).Methods: We assessed the progression of NPS and their influence on cognitive and functional progression in a group of FTD (n = 36) and AD patients (n = 47) at two different stages of the disease (2.5 years). A standardized scale was used to assess NPS-the Columbia University Scale for Psychopathology in Alzheimers Disease (CUSPAD)-which tracks different symptoms including depression, psychotic symptoms, as well as sleep and conduct problems. In addition, in a subsample of patients (AD n = 14 and FTD n = 14), we analyzed another group of NPS by using the Neuropsychiatric Inventory (NPI). Cognitive declines were tracked by using the Montreal Cognitive Assessment (MoCA) and the Mini-Mental State Examination (MMSE), while functionality was tracked by using the Lawton scale and the Barthel Index.Results: The presence of NPS
It is generally agreed, mortality and morbidity rates, in patients operated on for ruptured intracranial aneurysm, strictly depend upon the state at admission. Nevertheless, a precise definition of surgical mortality is still not available. Even the term morbidity still remains rather controversial for the lack of accurate evaluation scales. The wide range of parameters, affecting the composition of sample and outcome of patients, such as age, blood at CT scan and atherosclerosis at angiography, makes harder a correct statistical analysis of mortality and morbidity. Moreover, the gap between bleeding and admission, the management and choice of treatment, the selection of unicentric or multicentric studies, the level of the hospital introduce even more striking bias errors. Recent papers reported concrete improvements obtained by means of both aggressive therapeutical behaviour and adequate intensive care management. Among factors, producing improvement of the overall outcome, have to be also ...
Performance artist Marina Abramovic's piece Measuring the Magic of Mutual Gaze is both art installation and science experiment, in which volunteers
Neuropsychiatric symptoms are commonly related to interferon alpha treatment. The paper summarises the current knowledge about their aetiology, course
Mental disorders can be classified into panic attack, Anxiety, Stress, Eating disorder, Depression, Anorexia, Obesity and post traumatic disorder
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It is not only possible to work with early onset Parkinsons disease, it is probable. Most people who were working prior to diagnosis continue to work for some period of time afterwards.. How long will I be able to work? This is usually the more difficult question to answer. The length of time each person continues working will depend on many different factors. Some will be related to the disease itself such as symptoms, medication side effects, or progression of the disease; others are likely to be environmental factors including the overall economy and your particular employer.. When it comes to Parkinsons Disease in the workplace, it can be helpful to think of symptoms as internal and external as motor symptoms and non-motor symptoms. External symptoms are those your employer, co-workers or clients may notice such as tremor, slowness, rigidity, facial mask, etc.and those that involve more internal processes such as fatigue, sleepiness, apathy or difficulty concentrating/multi-tasking. ...
Learn 200 innovative, problem-stopping strategies to prevent or stop social, emotional, behavioral, and K-12 classroom management problems like bad attitudes, cyberbullying, poor motivation, truancy, delinquency, work refusal, school failure, disrespect, defiance, depression, trauma and apathy. Plus, earn $45-$60 college credit and free clock hours from our live, online and on-site professional development courses.. ...
My moms only brother, my uncle, passed away unexpectedly in November of 2009. It was a devastating loss, as I have a very small family, and it was the first time I had lost someone close to me. It took a heavy emotional toll; because of the pain I felt, and because of the unimaginable sadness my mom and grandparents were enduring. I fell into a deep depression shortly thereafter, a combination of apathy, numbness and anger. About 8 months later, at the behest of my parents, I began to see a psychologist. After a few sessions of him getting to know my history, I was diagnosed with not only acute depression, but also cyclothymia, a less severe form of bipolar disorder. He suspected that I had lived several years of my early adulthood under a mild, persistent depression. I rejected that notion at the time, thinking it was just the way I am, but in hindsight Ive come to realize that he was right ...
Learn 200 innovative, problem-stopping strategies to prevent or stop social, emotional, behavioral, and K-12 classroom management problems like bad attitudes, cyberbullying, poor motivation, truancy, delinquency, work refusal, school failure, disrespect, defiance, depression, trauma and apathy. Plus, earn $45-$60 college credit and free clock hours from our live, online and on-site professional development courses.. ...
This mutation was identified in a Korean woman with AD and a family history of the disease (Kim et al., 2020). Her symptoms, starting at age 40, included memory impairment, visuospatial dysfunction, abulia, apathy, and depression. Moreover, shortly prior to death and three years after disease onset, the patient developed myoclonus and seizures. Her APOE genotype was APOE3/APOE3.. This variant was not found in the gnomAD database, nor in 500 Korean controls.. Neuropathology ...
It has anti-tumor, antiseptic, detoxifying, diuretic, antidepressant effects; helps with apathy, anxiety and has stimulating, as well as soothing properties. It attenuates headaches, stress, fatigue, induces relaxation. It is effective against overload of the entire organism, has an impact onto the balance of the body, supports and revives the condition to be able to withstand stress. It stimulates brain function, which helps in concentration. It supports the digestive tract, increases bowel movement and helps the body get rid of harmful toxins that occur in the metabolism. It also helps in constipation and insufficient digestion, increases urine production and eliminates excess water from the body. It can effectively help with tired and stiff muscles, especially during excessive physical activities. It promotes the immune system and fights free radicals, which are considered the cause of many diseases ...
Needle-like leaves and smells like pine is what this herb resembles. It has a powerful phytochemical called carnasol. What is great about it is its ability to detox cancer causing substances. Usually people add Rosemary in their soups, vegetable dishes and rice. Internally rosemary herb is used for depression, apathy, nervous exhaustion, headaches and migraines associated with nervous tension or feeling cold, poor circulation, and digestive problems associated with anxiety. Externally for rheumatism, arthritis, neuralgia, muscular injuries, wounds, dandruff, and scurf ...
Under the influence of alcohol, the brain cells begin to gradually die off. This leads to inhibition of intellectual functions. The transmission of impulses between nerve endings slowing down, which leads to changes in behavior, and the inhibition of mental functions. First, it affects the mood, you receive the apathy that is again trying to suppress alcohol because of the desire to experience the same euphoria.. In addition, there is a restructuring of the hormonal system, there are problems with the production of serotonin that in a few years leads to chronic depression, caused by irreversible damage to brain cells.. ...
By learning how to stimulate your own dopamine levels naturally, you wont have to feel depressed or suffer from anxiety, apathy, and fear.
Whos-Bored.com - Lets Make Politics F***ing Awesome!Whos-Bored.com is on a mission to break through the yawn barrier of British politics and turn apathy into action!Posted by Hands up whos...
Even if you have a CI process in place that runs all your tests and measures your code coverage, if you allow the build to stay broken, all of your work is for nothing. At the same time, breaking a build should not be a criminal offense. You want your team members to commit their changes frequently. When they do this its okay to have a build fail. You dont want developer to be overly cautious when committing, fearing a broken build. What you dont want is to let a build stay broken. If you leave a build broken for a long period of time, it is a symptom of apathy about keeping the code base at a high level of quality. You should also never commit changes to a broken build. You dont know what impact your changes will have on a systems that is not passing all of its tests. Also remember that the team has ownership of the code. Anyone can fix the build (that includes you), it doesnt have the person who broke the test.. There are lots of ways to enforce this. The easiest way is that tools like ...
Most of the weight of your dehydrated brain would come from fats also known as lipids. In the remaining brain matter, you would find proteins and amino acids, traces of micronutrient and glucose. The brain is, of course, more than just the sum of its nutritional parts, but each component does have a distinct impact on functioning, development, mood and energy. So that post-lunch apathy or late-night alertness you might be feeling that is simply the effects of food on your brain. Of the facts in your brain, the superstars are Omega 3 and 6. These fatty acids which have been linked to preventing degenerative brain conditions must come from our diets. So eating omega rich food like nuts, seeds and fatty fish is crucial to the creation and maintenance of cell membranes.. While omegas are good fats for your brain, long term consumption of other fats, such as tans and saturated fats may compromise brain health. Meanwhile, protein and amino acids the building block nutrients of growth and development ...