The descending thoracic aorta arises from the aortic arch just after the origin of the left subclavian artery, at the inferior border of the fourth thoracic vertebrae. This point of transition is termed the aortic isthmus. In adults, the average diameter of the descending thoracic aorta is 2.8 cm in men and 2.6 cm in women.2 This narrows as it descends into the abdomen. It terminates as it enters the abdomen via the diaphragmatic aortic hiatus, at the 12th intercostal space. The thoracic aorta descends in the posterior mediastinum to the left of the vertebral column and gradually shifts to the midline at the aortic hiatus. It is surrounded by the thoracic aortic plexus. Anteriorly, the left pulmonary hilum crosses with the left main bronchus and left pulmonary artery being closely associated. Continuing inferiorly, the esophagus, pericardium, and diaphragm are also situated at the anterior border of the thoracic aorta. As the thoracic aorta descends, the esophagus crosses anteriorly and then ...
BioAssay record AID 602900 submitted by ChEMBL: Vasorelaxant activity in Wistar rat endothelium-intact aortic rings assessed as inhibition of phenylephrine-induced contractions at 10 to 100 uM after 10 to 60 mins.
BioAssay record AID 568587 submitted by ChEMBL: Vasodilatory activity in Sprague-Dawley rat thoracic aorta smooth muscle assessed as inhibition of phenylephrine-induced vasoconstriction.
Transmural concentration profiles of 125I-albumin in vivo were measured across the normal and balloon catheter-deendothelialized rabbit descending thoracic aorta as a function of time following intravenous injection. A tracer was injected 5 or 60 minutes after deendothelialization, and the animals were sacrificed after circulation times of 10, 30 or 60 minutes. The aorta was immediately excised and frozen flat between glass slides. Samples were serially sectioned parallel to the intimal surface in a refrigerated microtome, washed with trichloroacetic acid (TCA), and counted. Relative tissue concentration profiles of TCA-precipitable radioactivity from the media of control animals showed entry from both luminal and adventitial sides, as previously found with conscious normal rabbits, but spatial gradients at both luminal and medial-adventitial borders were less steep. Relative concentration levels in ballooned animals were 10- to 40-fold higher than in controls, and the profiles were flatter. ...
New pharmacotherapies are required to improve vessel graft protection and prevent vasoconstriction and spasm in CABG surgery. Previously we have studied adenosine (A) and lidocaine (L) relaxation in rat aortic rings, and reported a possible crosstalk between L relaxation and adenosine A(2a) receptor inhibition. The aim of the present study was to examine the effect of AL combination compared to A and L alone on relaxation in intact and denuded rat aortic rings and in guinea-pig pressurized mesenteric arterial segments. Aortic rings were harvested from Sprague-Dawley rats and equilibrated in an organ bath containing modified Krebs-Henseleit (KH) solution, pH 7.4, 37 degrees C. Rings were pre-contracted sub-maximally with 0.3 mu M norepinephrine, and the effects of increasing AL, A or L (up to 1.0 mM) were examined in intact and denuded rings. Mesenteric artery segments were isolated from guinea-pigs and mounted in an arteriograph containing KH solution and pressurised to 60 mmHg. Arteries were ...
Hey all. Im not here often as my kiddos issue was minor (ASD) and diagnosed at 6 months. It was just a waiting game to see if it would close until her 4 year check, which just occurred on 9/6. At that time, she had a complete echocardiogram, which had not been done since she was diagnosed with the ASD at 6 months - reason being is her pediatric cardio wasnt going to intervene until she hit 40 lbs., so he didnt think it was necessary. She always had an EKG at her check-ups, and that was it. Anywho, she had the echo and needless to say, my very hyper daughter was not the best patient. They seemed to take forever. They were taking shots off and on for about 1.5 hours. Tech called in cardiologist who was trying to get a shot, but having trouble as well. Finally, cardiologist tells us that the ASD is closed. I say - wait, even *I* can still here her murmur clear as day. She says, We need to talk. We go in and she draws a picture and explains in too simple terms that Lauren has a right
Transesophageal MRI of human thoracic aortae demonstrate the feasibility of the technique in healthy volunteers (Fig. 2A)and among patients with aortic atherosclerosis (Fig. 2B-D). Figure 2C, Dshows the corresponding TEMRI and TEE images of the distal aortic arch in a 77-year-old male patient with remote stroke, depicting heterogeneous atherosclerotic thickening, and this illustrates differences in circumferential plaque extent by the two methods. Figure 2Eis a longitudinal slice through the descending thoracic aorta and a portion of the arch of a normal subject, demonstrating the nonuniform SNR of the device (9,12). The SNR decreases linearly with radial distance from the probe, but substantially maintains its SNR along much of its length. In practical terms, this property allows TEMRI at multiple longitudinal locations over ∼20 cm without the need for repositioning the device.. Maximum and minimum WTs were 3.5 ± 1.2 mm and 1.2 ± 0.8 mm by TEE, and 3.3 ± 1.5 mm and 1.0 ± 0.7 mm by TEMRI, ...
Endovascular repair of the thoracic aorta has been adopted as the first-line therapy for much pathology. Initial results from the early-generation endografts have highlighted the potential of this technique. Newer-generation endografts have now been introduced into clinical practice and careful assessment of their performance should be mandatory. This study describes the initial experience with the Valiant endograft and makes comparisons with similar series documenting previous-generation endografts. Data were retrospectively collected on 180 patients treated with the Valiant endograft at seven European centers between March 2005 and October 2006. The patient cohort consisted of 66 patients with thoracic aneurysms, 22 with thoracoabdominal aneurysms, 19 with an acute aortic syndrome, 52 with aneurysmal degeneration of a chronic dissection, and 21 patients with traumatic aortic transection. The overall 30-day mortality for the series was 7.2%, with a stroke rate of 3.8% and a paraplegia rate of 3.3%.
Published in: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery (ISSN: 1078-5884), vol. 26, num. 2, p. 195-204 ...
With the advent of helical CT, the capability of noninvasive imaging of the thoracic aorta has been enhanced considerably. In this article, we describe the potential of helical CT using dual-slice technology to evaluate thoracic aortic diseases such
TY - JOUR. T1 - Treatment of dissecting aneurysms of the descending thoracic aorta.. AU - Juanteguy, J. M.. AU - Wilder, R. J.. PY - 1970/8. Y1 - 1970/8. UR - http://www.scopus.com/inward/record.url?scp=0014836896&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0014836896&partnerID=8YFLogxK. M3 - Article. C2 - 5450420. AN - SCOPUS:0014836896. VL - 36. SP - 493. EP - 498. JO - American Surgeon. JF - American Surgeon. SN - 0003-1348. IS - 8. ER - ...
FIGURE 1. (A) Schematic setup of the stereo-vision system to focus on a specimen, (B) specimen images taken by each camera, and (C) the reconstructed positions of markers affixed to the specimen in the 3D coordinate system. [Color figure can be viewed in the online issue, which is available at wileyonlinelibrary.com.] - Longitudinal differences in the mechanical properties of the thoracic aorta depend on circumferential regions.
The thoracic aorta begins at the level of vertebra T5 and continues through to the diaphragm at the level of T12, initially traveling within the mediastinum to the left of the
CT - Angiograms - Thoracic aorta angiogram is a way of looking at the blood vessels in different parts of your body. Learn more about this procedure.
The aorta originates from the left ventricle of the heart. It ends in the abdomen where it branches into the two common iliac arteries. The aorta has five separate segments. The descending aorta begins at the arch of the aorta (where it loops over the heart to begin its descent).
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02UX4KZ ICD-10 PCS Code descriptor cic Aorta, Ascending/Arch with Nonautologous Tissue Substitute, Percutaneous Endoscopic Approach
Xinmai Medical (688016) In-depth report: Domestic aorta and prolonged vascular intervention faucet. Report Summary Xinmai Xinmai Medical is currently the leading domestic manufacturer of aortic and vascular interventional products, with rich products and leading market share.. The company developed and launched the worlds first split-type stent graft in the field of thoracic aorta stent grafts. In the field of abdominal aortic stent grafts, although there is still a gap with imported products, it is gradually upgraded and is expected to achieve import substitution.. The layout of distal vascular interventional devices is extensive and rich. Drug replacement balloons have been applied for marketing, and the market potential has broken through.. The company has rich research reserves, continuous high-intensity research and development, and expansion of innovation capabilities. It is a leader in aortic intervention and interventional vascular 苏州桑拿网 disease segmentation.. The domestic ...
Abe and associates reported the trends in the early outcomes of surgical repair for acute type A aortic dissection in 11,843 patients from the Japan Cardiovascular Surgery Database between 2008 and 2015. Operative mortality was 9.5% and 30-day mortality was 7.6%. The number of surgically treated cases increased by 45% during the interval ...
Does anyone know what anatomical structure does the Thoracic Aorta become the ABD aorta? Also @ what structure does the common iliac become the Fem-po
In the previous studies, extensive accumulation and slower elimination of radioactivity from the eyeball and thoracic aorta were observed when 14C-YM758 was orally administered to nonalbino rats and/or albino rats. In albino rats, the plasma concentrations of the unchanged drug were detected only at 0.5 and 1 h, and the area under the curve extrapolated to 1 h ratio between the plasma concentrations of radioactivity and the unchanged drug was estimated to be 17.7%, indicating the existence of YM758 metabolites in rat plasma (Umehara et al., 2008f). In rat plasma, R1 (YM-385462), R2 (YM-385463), R3 (YM-385459), R4 (YM-252124), R9 (YM-234903), R10 and R19 (YM-396944) were detected as YM758 metabolites from radio-HPLC analyses (Fig. 4) (N. Nakada, Y. Susaki, T. Yokota, K. I. Umehara, T. Sonoda, E. Nakamura, T. Usui, T. Iwatsubo, and H. Kamimura, manuscript submitted for publication; Umehara et al., 2009a,b). Considering the previous findings and discussion on YM758 metabolites detected in rat ...
Ekkokardiografi.dk - en side om ultralydsundersøgelse af hjertet. Af Dansk Cardiologisk Selskabs arbejdsgruppe vedr. ekkokardiografi.
TY - JOUR. T1 - Gadolinium-enhanced 3D MRA of the aortic arch vessels the detection of atherosclerotic cerebrovascular occlusive disease. AU - Krinsky, Glenn. AU - Maya, Menahem. AU - Rofsky, Neil. AU - Lebowitz, Jonathan. AU - Nelson, Peter Kim. AU - Ambrosino, Michael. AU - Kaminer, Evan. AU - Earls, Jay. AU - Masters, Lynette. AU - Giangola, Gary. AU - Litt, Andrew. AU - Weinreb, Jeffrey. PY - 1998/4/18. Y1 - 1998/4/18. N2 - Purpose: Our goal was to evaluate non-breath-hold Gd-enhanced 3D MR angiography (MRA) for the detection of atherosclerotic occlusive disease of the aortic arch vessels and to compare image quality with two breath-hold techniques. Method: One hundred sixty consecutive patients with known or clinically suspected atherosclerotic cerebrovascular occlusive disease underwent Gd-enhanced 3D MRA of the aortic arch and great vessels. One hundred twenty-six examinations were performed with the body coil after infusion of 40 ml of Gd-DTPA; 89 of these were performed without breath- ...
This study was designed to determine whether the endothelium-derived relaxing factor induced by acetylcholine (1 microM) in rabbit thoracic aorta inhibits agonist-induced calcium mobilization, specifically calcium influx. Force generated in rings of rabbit thoracic aorta by norepinephrine (1 microM) was measured under isometric conditions. At the appropriate time during 1 microM acetylcholine-induced relaxation of 1 microM norepinephrine-contracted rabbit thoracic aorta, the rings were pulse-labelled with calcium-45 to measure calcium influx. When measured in this fashion, 1 microM acetylcholine decreased the 1 microM norepinephrine-induced increase in calcium influx. This effect was eliminated by removal of the endothelium and by atropine (1 microM), but not by indomethacin (14 microM). Acetylcholine (1 microM) also blocked the 60 mM potassium-chloride-induced increase in calcium influx without dramatically affecting force. The phasic contraction produced by norepinephrine (1 microM) with 2 mM ...
METHODS AND RESULTS Normal or hypercholesterolemic rabbits received intravenous L-arginine (10 mg/kg/min) or vehicle for 70 minutes. Subsequently, animals were killed, thoracic aortas were harvested, and vascular rings were studied in vitro. Rings were contracted by norepinephrine and relaxed by acetylcholine chloride or sodium nitroprusside. Vasorelaxation was quantified by determining the maximal response (expressed as percent relaxation of the contraction) and the ED50 (dose of drug inducing 50% relaxation; expressed as -log M). In vessels from hypercholesterolemic animals receiving vehicle, there was a fivefold rightward shift in sensitivity to acetylcholine compared with normal animals (p = 0.05, n = 5 in each group). In vessels from hypercholesterolemic animals, L-arginine augmented the maximal response to acetylcholine (83 +/- 16% versus 60 +/- 15%, p = 0.04 versus vehicle) and increased the sensitivity to acetylcholine (ED50 value: 6.7 +/- 0.2 versus 6.2 +/- 0.2, p less than 0.05 versus ...
PURPOSE: Traumatic rupture of the thoracic aorta secondary to blunt chest trauma is a life-threatening emergency and a common cause of death, usually following violent collisions. The objective of this retrospective report was to evaluate the efficacy of endovascular treatment of thoracic aortic disruptions with a single commercially available stent-graft.. METHODS: Nine men (mean age 29.5 years) were admitted to our institution between January 2003 and January 2006 due to blunt aortic trauma following violent motor vehicle collisions. Plain chest radiography, spiral computed tomography, aortography, and transesophageal echocardiography were used for diagnostic purposes in all cases. All patients were diagnosed with contained extramural thoracic aortic hematomas, secondary to aortic disruption. One patient was also diagnosed with a traumatic thoracic aortic dissection, secondary to blunt trauma. All subjects were poor surgical candidates, due to major injuries such as multiple bone fractures, ...
Patients involved in high-energy blunt trauma involving rapid deceleration are at significant risk for blunt aortic injury. The majority of blunt aortic injuries are due to motor vehicle collision. In the United States, blunt aortic injury is the sec
Right aortic arch with aberrant left subclavian artery (RAA/aLSCA) is a rare aortic arch anomaly. The clinical association of aLSCA stenosis with RAA/aLSCA has not yet been fully elucidated. The aim of this study was to investigate the diagnosis, incidence, management and outcome of aLSCA stenosis in infants with prenatally diagnosed RAA/aLSCA. Ten fetuses who were diagnosed as having RAA/aLSCA in Kyushu University Hospital between January 2011 and December 2014 were enrolled. The maternal and child medical records were reviewed to investigate sex, gestational age at the fetal diagnosis, gestational age and body weight at birth, the findings of computed tomography (CT), Doppler ultrasonography of the vertebral artery and angiography, and the complications and outcomes of aLSCA stenosis ...
Sigma-Aldrich offers abstracts and full-text articles by [Ga-Young Suh, Ramin E Beygui, Dominik Fleischmann, Christopher P Cheng].
This study was designed to determine whether the relaxant effect of apigenin was endothelium dependent and to examine the possible antiproliferative effect of apigenin. Apigenin relaxed the phenylephrine-precontracted endothelium-intact aortic rings with IC50 value of 3.7+/-0.5 muM and removal of a functional endothelium significantly attenuated this relaxation (IC50 = 8.2+/-0.9 muM). However, apigenin did not affect the 0.1 muM phorbol 12,13-dibutyrate-induced contraction (IC50 = 34.6 +/- 1.2 muM) within the concentration range that relaxed the phenylephrine-contracted arteries, suggesting that apigenin did not influence protein kinase C-mediated contractile mechanisms in rat aorta. Pretreatment of apigenin significantly potentiated the relaxant effect of acetylcholine on phenylephrine-induced contraction. Pretreatment with N-G-nitro-L-arginine methyl ester (L-NAME) or methylene blue reduced the relaxant effect of apigenin. Apigenin (10 muM) increased the guanosine 3′,5′-cyclic ...
The major artery carrying blood from the heart to blood vessels throughout the body, the aorta is about one inch in diameter. From the heart, the thoracic aorta extends upward (ascending aorta) before arching (aortic arch) and extending downward through the chest (descending aorta). Along the way, arteries branching from the thoracic aorta supply oxygen-rich blood to the heart muscle, head and neck, arms, and chest. Thoracic surgeons such as Dr. Raissi specialize in repair and replacement techniques for the ascending aorta, aortic arch and descending aorta - those within the chest cavity. When the aorta passes through the diaphragm and into the abdomen, it becomes known as the abdominal aorta and its arteries supply blood to the abdomen and lower extremities. A localized weakness or bulge in the aorta - an aneurysm - can become life-threatening if it ruptures, and victims often have few, if any, noticeable warning signs. Although prolonged high blood pressure and arterial plaque buildup are ...
Aortic arch reconstruction using the main pulmonary artery and ascending aorta, atrial septectomy, and modified Blalock-Taussig shunt provides unobstructed systemic blood flow and adequate coronary artery perfusion ...
Definition of esophageal branches of the thoracic aorta. Provided by Stedmans medical dictionary and Drugs.com. Includes medical terms and definitions.
Background: Large aortic arch plaques are associated with ischemic stroke. Carotid intima-media thickness (CIMT) is a marker of subclinical atherosclerosis and a strong predictor of cardiovascular disease and stroke. The association between CIMT and aortic arch plaques has been studied in patients with strokes, but not in the general population. The aim of this study was to investigate this association in an elderly asymptomatic cohort and to assess the possibility of using CIMT to predict the presence or absence of large aortic arch plaques. ...
Abnormally stiffened arteries are present in individuals with diabetes and are associated with an increase in cardiovascular events, LV afterload, and exercise intolerance (1,4,9). In this study, we sought to determine if individuals with IFG exhibited abnormal stiffening of the arterial tree (including the proximal thoracic aorta) that in studies of individuals with diabetes is associated independently with adverse cardiovascular events. There are two important findings in this study: Total vascular stiffness is worse in subjects with IFG compared with those with NFG. This finding is true regardless of age, sex, ethnicity, or other factors associated with abnormal vascular stiffening (Table 2; Fig. 2). After adjustment for factors known to influence vascular stiffness, proximal thoracic aortic stiffness and LV mass are similar in individuals with IFG and NFG (Figs. 3 and 4). In patients with diabetes, however, both proximal thoracic aortic stiffness and LV mass are elevated (Figs. 3 and ...
A new potent, selective and p.o. active serotonergic [5-hydroxytryptamine (5-HT2)] receptor antagonist, SR 46349B [trans, 4-([3Z)3-(2-dimethylaminoethyl)oxyimino-3(2-flurophenyl++ +)propen-1-yl]phenol hemifumarate) has been characterized by a series of "in vitro" and "in vivo" methods. Based upon binding studies with 5-HT2 receptors in rat brain cortical membranes and blockade of 5-HT-induced contractions in isolated tissues (rabbit thoracic aorta, rat jugular vein, rat caudal artery, rat uterus and guinea pig trachea), SR 46349B showed high affinity for 5-HT2 receptors. Furthermore, SR 46349B displayed moderate affinity for the 5-HT1C receptor and had no affinity for the other 5-HT1 subclass (5-HT1A, 5-HT1B or 5-HT1D), dopamine (D1 or D2), "alpha" adrenergic (alpha-1 or alpha-2), sodium and calcium channel and histamine (H1) receptors. It did not interact with histamine (H1), alpha-1 adrenergic and 5-HT3 receptors in smooth muscle preparations. No inhibition of the uptake of norepinephrine, ...
TY - JOUR. T1 - Management of arch hypoplasia after successful coarctation repair. AU - DeLeon, Maryann M.. AU - DeLeon, Serafin Y.. AU - Quinones, Jose A.. AU - Roughneen, Patrick. AU - Magliato, Kathy E.. AU - Vitullo, Dolores A.. AU - Cetta, Frank. AU - Bell, Timothy J.. AU - Fisher, Elizabeth A.. PY - 1997. Y1 - 1997. N2 - Background. Pronounced arch obstruction can be seen after a well-repaired coarctation, and this probably results from the failure of a somewhat hypoplastic arch to grow or from clamp injury at the time of the initial repair, or from both causes. Because of mediastinal adhesions and minimal collateral circulation, use of extraanatomic bypass grafts appears to be the preferred approach. Methods. Six children or young adults presented with arch obstruction over a 3-year period. Their mean age was 13.5 ± 4 years, and the mean interval from the time of the initial repair was 10 ± 4 years. The mean age of the patients at the time of the initial repair was 3.2 ± 5 years. ...
Purpose of Review The purpose of this manuscript is to review the surgical techniques of aortic arch repair, imaging techniques for evaluating the pre- and post-operative aortic arch, and both normal...
Diseases of the cardiovascular system are predicted to be the leading worldwide cause of death by 2030.1,2 Cardiovascular diseases (CVDs) are characterised as diseases of lifestyle, associated with a Western diet and low levels of physical activity. However, ischaemic heart disease and other non-communicable diseases are likely to be major contributors to mortality in sub-Saharan Africa.2. Forms of these diseases (once associated with ageing3) are common in younger individuals; atherosclerotic lesions, aneurysms and strokes have been reported in children and young adults.4-6 Fatty dots and streaks, which may represent the early stages of atherosclerosis, have been found in the aortas of babies and infants.6. Risk factors in the increasing prevalence of CVD include cigarette smoking, high-fat diet, high cholesterol levels, obesity, diabetes, hypertension and HIV infection.1,4,7 Antiretroviral treatment for HIV-positive individuals also increases the risk of developing CVD.8. Certain ...
enlarged aorta - MedHelps enlarged aorta Center for Information, Symptoms, Resources, Treatments and Tools for enlarged aorta. Find enlarged aorta information, treatments for enlarged aorta and enlarged aorta symptoms.
The current study has demonstrated significant regional variation in access to treatment, the organization of clinical services, and mortality for patients with TAD in England. An analysis of HES data demonstrated that the variation in the proportion of TAD patients treated within 6 months of diagnosis ranged from 7.6% to 31.5% among counties and remained statistically significant after adjustment for potential confounders, including comorbidity, deprivation, disease severity, and population density. Regional variation was not associated with differences in mortality rates for patients that received treatment, but was associated with differences in mortality in those that did not receive treatment, implying that inequity in access to care has important effects on outcome. The analysis of NASCA data indicated wide regional variation in the volume and complexity of TAD cases undertaken in English cardiac centers. Centers undertaking higher volumes were more likely to treat more‐complex disease ...
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The speeds at which an aortic laceration can occur in an auto crash vary greatly. Doctors use the term Delta V when determining forces causing aortic tears.
Penyakit Aneurisma Aorta - Aneurisma aorta atau aneurisme aorta merupakan pembengkakan pembuluh aorta perut atau pembesaran aorta, pembuluh darah utama yang menyalurkan darah ke tubuh pada level abdomen. Baca Juga [more…] ...
noun the descending part of the aorta that branches into the thoracic and abdominal aortae • Hypernyms: ↑aorta * * * noun : the part of the aorta from the arch to its bifurcation that passes downward in the thoracic and abdominal cavities
In the early stages of fetal development, two aortic arches come from the heart, ascend upward and then descend behind the heart merging together to become a single aorta. As the heart develops normally, the right-sided arch disappears, leaving the left-sided arch to ascend upward and continue to the descending aorta behind the heart. The normally developed left-sided aorta lies in front of the trachea, or breathing tube, and esophagus, or swallowing tube.. A vascular ring is a defect where the arch vessels encircle the breathing and swallowing tubes.This is caused by abnormal development of the aortic arches. If both arches stay open it is called a double aortic arch. The two arches surround the breathing and swallowing tubes and may cause narrowing or compression of these structures and lead to breathing and/or feeding difficulties. In another form of a vascular ring, the left-sided arch disappears, and the right-sided arch stays open. If this is associated with an abnormal origin of the blood ...
Oxygenated blood begins its course down the chest through the thoracic aorta, a major blood vessel with branches that serve the chest muscles and lungs. This becomes the abdominal aorta.
Relaxation of Rat Aorta by Farrerol Correlates with Potency to Reduce Intracellular Calcium of VSMCs. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Researchers investigate the role of arterial stiffness in memory decline in older adults. A flexible aorta may be key to maintaining cognitive ability.
Study Flashcards On Ascending Aorta at Cram.com. Quickly memorize the terms, phrases and much more. Cram.com makes it easy to get the grade you want!