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TY - JOUR. T1 - Oxygen radical absorbance capacity (ORAC) of cyclodextrin-solubilized flavonoids, resveratrol and astaxanthin as measured with the ORAC-EPR method. AU - Sueishi, Yoshimi. AU - Ishikawa, Misa. AU - Yoshioka, Daisuke. AU - Endoh, Nobuyuki. AU - Oowada, Shigeru. AU - Shimmei, Masashi. AU - Fujii, Hirotada. AU - Kotake, Yashige. PY - 2012/3. Y1 - 2012/3. N2 - Recently, we proposed an oxygen radical absorbance capacity method that directly quantifies the antioxidants scavenging capacity against free radicals and evaluated the radical scavenging abilities for water soluble antioxidant compounds. In this study, we determined the radical scavenging abilities of lipophilic antioxidants which were solubilized by cyclodextrin in water. Commonly employed fluorescence-based method measures the antioxidants protection capability for the fluorescent probe, while we directly quantify free-radical level using electron para- magnetic resonance spin trapping technique. In addition, the spin ...
Oxygen radical absorbance capacity (ORAC) is a method of measuring antioxidant capacities in biological samples in vitro. A wide variety of foods have been tested using this method, with certain spices, berries and legumes rated highly in extensive tables once published by the United States Department of Agriculture (USDA), but withdrawn in 2012 since no correlation between test results and biological activity could be determined, stating that no physiological proof in vivo existed in support of the free-radical theory. Although not all have been unilaterally dismissive, the majority position supports the USDA decision. Alternative measurements include the Folin-Ciocalteu reagent, and the Trolox equivalent antioxidant capacity assay. The assay measures the oxidative degradation of the fluorescent molecule (either beta-phycoerythrin or fluorescein) after being mixed with free radical generators such as azo-initiator compounds. Azo-initiators are considered to produce the peroxyl radical by ...
Background: Patients with end-stage renal disease undergoing hemodialysis (HD) are exposed to oxidative stress, which is associated with an impairment of antioxidant defense and an overproduction of oxidative stress markers. Oxidative stress plays a significant role in the development of inflammation in these patients. Objectives: The high incidence of cardiovascular diseases in HD patients is now well established and the involvement of oxidative stress has been hypothesized in these phenomena. This study focused on a comparison of plasma total antioxidant capacity (TAC) and lipid peroxidation product and evaluated the relationship between them and high-sensitivity C-reactive protein in patients on HD. Subjects and Methods: Plasma (TAC), lipid peroxidation products, malondialdehyde (MDA) as well as high-sensitivity C-reactive protein were determined in 30 patients on HD and in 20 normal controls (NC). Results: TAC and MDA levels were significantly higher in patients on HD than in the control ...
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Several lines of evidence suggested that antioxidants might play a protective role against high-risk human papillomavirus (hrHPV) infection and cervical cancer. However, the effect of combined intake of antioxidants has not been investigated thus far. The current cross-sectional study aimed to understand the relationship between dietary antioxidant intake and the risk of high-risk HPV (hrHPV) infection among 251 Italian women with normal cervical cytology. Women were tested for hrHPV using the Digene HC2 HPV DNA Test. Dietary antioxidant intakes were assessed using a semi-quantitative food frequency questionnaire, and a Composite Dietary Antioxidant Index (CDAI) was constructed on the basis of zinc, selenium, manganese, vitamin A, vitamin C, vitamin E, carotenoid, and flavonoid intake. Logistic regression analysis was used to assess odds ratio (OR) and 95% confidence interval (95% CI) for the associations of antioxidant intakes or CDAI with hrHPV status, adjusting for age, smoking status, body mass
article{d66ae562-8be9-46fc-bbf8-0060fc9536f8, abstract = {The aim of the study was to investigate whether a supplement of antioxidants to subjects with a high working pace can influence the antioxidant capacity. The study was parallel and double blind with 98 subjects randomised into two groups. One of the groups was given a test drink with antioxidants for 4 weeks (450 ml/day) while the other group took a corresponding amount of placebo drink. The test drink contained: 2 mg beta-carotene/100 ml, 40 mg alpha-tocopherol/100 ml, 80 mg ascorbic acid/100 ml, 2 mg pyridoxine/100 ml, 15 mg magnesium/100 ml, 0.2 mg manganese/100 ml, 1 mg zinc/100 ml, 0.1 mg copper/100 ml and 10 μg selenium/100 ml. Consumption of the test drink for 4 weeks increased the total plasma antioxidant capacity by 7% (ferric reducing ability of plasma method, P<0.05 compared with the placebo group), and the content of selenium and selenoprotein P in serum was raised by 16-17% (P<0.001 compared with the placebo group). No ...
A high intake of dietary antioxidant compounds has been hypothesized to be an appropriate strategy to reduce gastric cancer (GC) development. We investigated the effect of dietary total antioxidant capacity (TAC) in relation to GC in the European Prospective Investigation into Cancer (EPIC) study including 23 centers in 10 European countries. A total of 521,457 subjects (153,447 men) aged mostly 35-70 years old, were recruited largely between 1992 and 1998. Ferric reducing antioxidant potential (FRAP) and total radical-trapping antioxidant parameter (TRAP), measuring reducing and chain-breaking antioxidant capacity were used to measure dietary TAC from plant foods. Dietary antioxidant intake is associated with a reduction in the risk of GC for both FRAP (adjusted HR 0.66; 95%CI (0.46-0.95) and TRAP (adjusted HR 0.61; 95%CI (0.43-0.87) (highest vs. lowest quintile). The association was observed for both cardia and noncardia cancers. A clear effect was observed in smokers with a significant reduction in
A high intake of dietary antioxidant compounds has been hypothesized to be an appropriate strategy to reduce gastric cancer (GC) development. We investigated the effect of dietary total antioxidant capacity (TAC) in relation to GC in the European Prospective Investigation into Cancer (EPIC) study including 23 centers in 10 European countries. A total of 521,457 subjects (153,447 men) aged mostly 35-70 years old, were recruited largely between 1992 and 1998. Ferric reducing antioxidant potential (FRAP) and total radical-trapping antioxidant parameter (TRAP), measuring reducing and chain-breaking antioxidant capacity were used to measure dietary TAC from plant foods. Dietary antioxidant intake is associated with a reduction in the risk of GC for both FRAP (adjusted HR 0.66; 95%CI (0.46-0.95) and TRAP (adjusted HR 0.61; 95%CI (0.43-0.87) (highest vs. lowest quintile). The association was observed for both cardia and noncardia cancers. A clear effect was observed in smokers with a significant reduction in
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Resistance training is known to promote the generation of reactive oxygen species. Although this can likely upregulate the natural, endogenous antioxidant defense systems, high amounts of reactive oxygen species can cause skeletal muscle damage, fatigue, and impair recovery. To prevent these, antioxidant supplements are commonly consumed along with exercise. Recently, it has been shown that these reactive oxygen species are important for the cellular adaptation process, acting as redox signaling molecules. However, most of the research regarding antioxidant status and antioxidant supplementation with exercise has focused on endurance training. In this review, the authors discuss the evidence for resistance training modulating the antioxidant status. They also highlight the effects of combining antioxidant supplementation with resistance training on training-induced skeletal muscle adaptations. ...
Antioxidants are health beneficial compounds that can protect cells from the damage caused by unstable molecules known as reactive oxygen species (ROS). This work reports the capacity assay of both lipophilic and hydrophilic antioxidants simultaneously, by making use of their host-guest complexes with methyl-beta-cyclodextrin (M-beta-CD), a cyclic oligosaccharide, in acetonated aqueous medium using the cupric reducing antioxidant capacity (CUPRAC) method. Thus the order of antioxidant potency of various compounds irrespective of their lipophilicity could be established in the same solvent medium. M-beta-CD was introduced as the water solubility enhancer for lipophilic antioxidants. Two percent M-beta-CD (w/v) in an acetone-H2O (9:1, v/v) mixture was found to sufficiently solubilize beta-carotene, lycopene, vitamin E, vitamin C, synthetic antioxidants and other phenolic antioxidants. This assay was validated through linearity, additivity, precision, and recovery. The validation results ...
These free radicals which are rogue cells attack the body and damage the cell membranes, impairing the life span of cells in your body.. Antioxidant supplements help to ward off the harmful effects of these free radicals which have on your cells.. Vitamin C is a powerful antioxidant supplement which performs various functions. It aids the responses of the human immune system.. This antioxidant supplement is crucial when it comes to the production of collagen in the body. Collagen acts as a connective tissue throughout your body therefore it is a very important compound.. Sources of vitamin C include green beans, tomatoes, papaya, citrus fruits, strawberries, broccoli, cantaloupes, and red bell peppers.. Vitamin E is also an important antioxidant supplement for the human health. Vitamin E helps the body by aiding the immune system. This vitamin also helps to protect the body against the threat of cancer and cardiovascular diseases. There are many benefits with vitamin supplements.. If you want to ...
TY - JOUR. T1 - Effect of acute intervention with flavonoid-rich juice on the plasma antioxidant capacity. AU - Niwat, Chutamat. AU - George, Trevor. AU - Gordon, Michael. AU - Lovegrove, Julie. PY - 2007/11/1. Y1 - 2007/11/1. N2 - Epidemiological data provide evidence that consumption of a diet rich in fruit and vegetables is associated with a reduction in the incidence of CVD. One possible mechanism for the protective effect of fruits and vegetables is the antioxidant activity of several compounds, including vitamins, minerals, fibre and other phytochemicals. Flavonoids are a group of phenolic compounds with strong antioxidant activity that are present in fruits, vegetables and other plant foods and play a role in the reduction of the incidence of chronic diseases such as CVD. However, very little is known about the amount of flavonoids absorbed from the diet and the reliability of plasma biomarkers. The present study set out to investigate the pharmacokinetics of flavonoid uptake and the ...
Fresh human milk has a higher antioxidant capacity than infant formula. This result is consistent with the study of Shoji et al,10 who found increased urinary 8-hydroxy-2′-deoxyguanosine excretion in formula fed infants compared with breast fed infants. Schwarz et al11 found similar results by measuring breath ethane concentrations in breast fed and formula fed infants. Although most studies showed that human milk had a higher antioxidant capacity than formula, one study by Alberti-Fidanza et al12 using the oxygen radical absorbance capacity assay, suggested that formula may have higher antioxidant capacity than human milk. The difference in these findings may be due to the different methods used to determine the antioxidant capacity of human milk. An improved oxygen radical absorbance capacity assay has been developed and validated using fluorescein.13,14 Friel et al15 showed that human milk has better antioxidant protection than formulas, perhaps because of the higher iron content of ...
Have you ever heard of antioxidants? Chances are you have heard about antioxidants you can eat. But, did you know there are antioxidants for your skin? The most beneficial antioxidants for your skin are CE ferulic and phloretin. You will be amazed to learn what these two antioxidants can do for your skin.. What is CE ferulic? CE Ferulic contains a combination of 15% vitamin C, 1% vitamin E and 0.5% ferulic acid. This incredible antioxidant protects your skin from free radicals that cause aging.. What are Phloretin antioxidants? This powerful antioxidant combination provides environmental protection for your skin. Phloretin CF contains 10% vitamin C and 0.5% ferulic acid.. Why are antioxidants good for your skin? Antioxidants are known for their ability to improve the appearance of the skin and reduce the signs of aging. Antioxidants protect skin from harmful free radicals.. Where to find antioxidants for your skin? The dermatologist office is the best place for antioxidant treatments. You need ...
TY - JOUR. T1 - Mitochondrial targeted antioxidant peptide ameliorates hypertensive cardiomyopathy. AU - Dai, Dao Fu. AU - Chen, Tony. AU - Szeto, Hazel. AU - Nieves-Cintrón, Madeline. AU - Kutyavin, Vassily. AU - Santana, Luis F.. AU - Rabinovitch, Peter S.. PY - 2011/6/28. Y1 - 2011/6/28. N2 - Objectives: We investigated the effect of reducing mitochondrial oxidative stress by the mitochondrial-targeted antioxidant peptide SS-31 in hypertensive cardiomyopathy. Background: Oxidative stress has been implicated in hypertensive cardiovascular diseases. Mitochondria and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase have been proposed as primary sites of reactive oxygen species (ROS) generation. Methods: The mitochondrial targeted antioxidant peptide SS-31 was used to determine the role of mitochondrial oxidative stress in angiotensin II (Ang)-induced cardiomyopathy as well as in Gαq overexpressing mice with heart failure. Results: Ang induces mitochondrial ROS in neonatal ...
This study was designed to elucidate the effect of ascorbic acid on salivary total antioxidant capacity in smokers. In this single blind crossover clinical trial, the whole unstimulated saliva of 30 smokers, who were randomly divided into two groups, was collected. In the first phase after the saliva collection, one group of patients took 500 mg of vitamin C powder, for 3 weeks. Then, saliva of all patients was collected. After a one-week wash-out period, vitamin C was given to the other group. The collection of saliva was done after 3 weeks. Total antioxidant capacity was measured. Statistic evaluation was performed by Repeated Measured ANOVA, Independent sample t-test and Covariate test. The mean of total antioxidant capacity with and without using vitamin C was 0.511 ± 0.155 (U/mL) and 0.555 ± 0.171 (U/mL), respectively. This variability was not significant (p = 0.605). Oxidative stress from cigarette smoke was not decreased significantly with using vitamin C.
This study will investigate the effect of ENI Patented Whole Grape Extract versus placebo on antioxidant status. The primary objective is to determine antioxidant status by measuring total antioxidant capacity and superoxide dismutase (SOD) in blood and 8-OHdG and 8-isoprostane in first morning void urine samples prior to and after six weeks of supplementation with ENI Patented Whole Grape Extract.. Secondary objectives will include the assessment of oxidized LDL (oxLDL) and safety evaluations:. ...
If your goal is to get a glowing skin tone, end clogged pores, and end acne once and for all, then antioxidants are a goldmine.. Supercharging your bodily antioxidant supplies is the joint most effective strategy for acne. Overall, it is one of the most enjoyable ways to clear acne too. Your near infallible rule is that the more flavoursome the fruit or herb, the heavier and more diverse the antioxidant count.. That said, theres a common perception that plant foods are the only source of antioxidants, which is wrong. A banana, for example, contains only a few antioxidants, like rutin. Meanwhile a slab of beef, not associated with antioxidants in adverts, is drenched in minerals and aids your body in manufacturing its own antioxidants.. The antioxidant content of a food does not totally determine the end result in your bloodstream and skin. To give you an easily consultable list for rapid action, here are 23 foods with strong powers to increase bodily antioxidant levels, and hence strong powers ...
Local resource for antioxidant supplements for athletes in Joplin. Includes detailed information on local businesses that give access to antioxidant supplements such as vitamin C, vitamin E, and beta carotene, as well as advice and content on free radicals and antioxidants.
Local resource for antioxidant supplements for athletes in Lincoln. Includes detailed information on local businesses that give access to antioxidant supplements such as vitamin C, vitamin E, and beta carotene, as well as advice and content on free radicals and antioxidants.
The objective of this study was to determine whether running a 24-h race would cause oxidative damage and changes in the blood antioxidant defense capacity in endurance-trained athletes. Fourteen male amateur runners (mean age 43.0±10.8 y, body weight 64.3±7.2 kg height 171±5 cm, weekly covered distance 81±43 km, training history 8±9 y) who participated in a 24-hr ultra-marathon and volunteered to give blood samples during the race were enrolled for this study. Blood samples were taken before the run, after completing the marathon distance (42.217 km), after 12 h and at the conclusion of the race.The capacity of erythrocyte antioxidant defense system was evaluated by measuring the activities of superoxide dismutase (SOD), glutathione peroxidase (GPX), catalase (CAT), glutathione reductase (GR), concentrations of non-enzymatic antioxidants (uric acid and glutathione-GSH), and selected biomarkers of oxidative stress (i.e., plasma level of malondialdehyde (MDA) and plasma antioxidant capacity ...
If this recipe for Antioxidant Shooters has caught your eye, I have a feeling you are aware that pomegranate juice, strawberries and blueberries are filled with antioxidants. With the addition of beets, this recipe is SUPER high in antioxidants. If you dont have time to cook beets, you can often find them on the salad bar at a high end or gourmet grocery store. What is interesting about beets is not the fact that they are rich in antioxidants, but the unusual mix of antioxidants that they contain. Beets have unique antioxidants since they get their red color primarily from betalain antioxidant pigments (and not primarily from anthocyanins). This combined with being a very good source of the antioxidant manganese and vitamin C, provides antioxidant support in a different way than other antioxidant-rich vegetables.. Have you heard the term but wonder why antioxidants are important? Antioxidants offer a number of health benefits and can help possibly prevent diseases, ranging from cancer to ...
Among the fruits specifically highlighted as beneficial were grapes, which, after consumption resulted in almost double the amount of recommended total antioxidant capacity needed to counteract the deficit associated with consuming 1000 calories of food.. Dr. Ronald L. Prior of the USDAs Arkansas Childrens Nutrition Center, widely recognized as a pioneer of the ORAC (Oxygen Radical Absorbance Capacity) technique for measuring antioxidant capacity in foods, shared his findings regarding the natural state of oxidative stress in the body that results from eating a meal and the ability to counteract it in humans following consumption of certain fruits.. Prior showed that the metabolic process of digesting a meal with no antioxidants -- just fat, carbohydrate and protein -- causes a decline in antioxidant capacity of the blood which creates a temporary state of oxidative stress. This deficit can be prevented by consuming high antioxidant fruits such as grapes, which in this study provided almost ...
Different kinds of antioxidants. Antioxidants are types of nutrients and enzymes that can help promote health and may play a role in reducing your risk of chronic illnesses. They do this by combatting the free radicals produced as a result of oxidation.. Not all forms of antioxidants are the same. In fact, there are different types. Antioxidants can be soluble (i.e. they dissolve) in either water or in fat. Both types of antioxidants are important, as they can both be attacked by free radicals.. Water soluble antioxidants include vitamin C and polyphenols (antioxidants specifically from plants), whereas fat soluble antioxidants include vitamin A, vitamin E, carotenoids and lipoic acid.. Can Oxidative Stress be prevented?. Some of the effects of oxidative stress can be counteracted. Your body is unlikely to produce enough antioxidants to fight all the free radicals, so you can do your bit to support it. Trying to avoid some of the causes of free radicals may be beneficial, as well as eating a ...
Many phytochemicals possess antioxidant and cancer-preventive properties, some putatively through antioxidant response elementCmediated phase II rate of metabolism, entailing mutagen/oxidant quenching. moderate, and none was apparent for glutathione S-transferase pi proteins manifestation. Measurements of reactive air varieties and glutathione/oxidized glutathione percentage demonstrated an antioxidant impact for DMEBP, but no certain effect was discovered for TRES in NHBE cells. Publicity of NHBE cells to H2O2 induced nuclear translocation of nuclear element erythroid 2Crelated element 2, but this translocation had not been inhibited by TRES and DMEBP considerably. These studies also show that strength and low toxicity may for just two potential NQO1-inducing real estate agents align, TRES and DMEBP. screening method of display 800 substances in an all natural items library, this scholarly research offers determined 2,3-dihydroxy-4-methoxy-4-ethoxybenzophenone (derivative, myrtle extract, and ...
Shelf life of cooked ground beef links with no, low, or high concentrations of a blend of natural plant extract antioxidant were compared to evaluate lipid oxidation over time. When no antioxidants were added, samples stored nine days or beyond were more oxidized than the samples with the addition of an antioxidant. No differences in lipid oxidation were observed between 0.13% and 0.20% antioxidant concentrations during similar days of refrigerated storage days. Therefore, the addition of natural antioxidants were effective at reducing oxidative rancidity, regardless the concentration of antioxidant.
Geographically, this report split global into several key Regions, with sales (K MT), revenue (Million USD), market share and growth rate of Water-soluble Antioxidant for these regions, from 2012 to 2022 (forecast), covering. United States. China. Europe. Japan. Southeast Asia. India. Ask for sample copy @ https://www.researchtrades.com/request-sample/1405955 Global Water-soluble Antioxidant market competition by top manufacturers/players, with Water-soluble Antioxidant sales volume, Price (USD/MT), revenue (Million USD) and market share for each manufacturer/player; the top players including. BASF. Chemtura. SONGWON. SI (Albemarle). Double Bond Chemical. CYTEC (SOLVAY). Akzonobel. Clariant. Lanxess. Dow. Sumitomo Chemical. Adeka. Innospec. Kumho Petrochemical. Lubrizol. EVONIK. Addivant. Akrochem. Eastman. On the basis of product, this report displays the production, revenue, price, market share and growth rate of each type, primarily split into. Ascorbic Acid. Tea Polyphenols. Others. Buy a ...
Previous observations have indicated that the red peel areas of grapefruit with high lycopene concentrations were more tolerant to CI than yellow peel areas (Lado et al., 2015a). Because lycopene is a carotene with powerful antioxidant capacity, this study investigated whether the CI tolerance of the lycopene-accumulating rind of grapefruit may be due to an enhancement of the enzymatic and/or nonenzymatic antioxidant systems. Total antioxidant capacity, antioxidant metabolite (GSH and AsA) contents, and antioxidant enzyme (GR [glutathione reductase], ascorbate peroxidase [APX], catalase [CAT] and superoxide dismutase [SOD]) activity and gene expression were measured in the peel of Star Ruby grapefruit with contrasting CI tolerance during storage at 2 C for up to 58 d. The peel of CI-tolerant fruit exhibited a lower lipid peroxidation level (MDA content). The hydrogen peroxide concentration was similar after 3 weeks of storage, when the differences in chilling damage between sensitive and ...
The antioxidant capacity and the phenolic content of hydroalcoholic macerations from leaves, inflorescences, stems and roots of species of the genus Pluchea were also compared. Leaf extracts followed by inflorescence extracts showed the highest values of antioxidant capacity. The species P. carolinensis was used as a model to evaluate the antioxidant capacity in two locations and two phenological stages and also for monitoring the antioxidant capacity over some months. Natural adult specimens presented a higher phenolic content, as well as higher antioxidant capacity than young and cultivated specimens. Maximal antioxidant capacity and concentrations in phenolics were recorded in January, September and December; over the blooming stage (March), the antioxidant capacity was minimal. Two different solvents of extraction and two methods were also screened for extracting the maximal concentrations in antioxidants. Hydroalcoholic extractions showed higher antioxidant capacity than ethanolic ones. ...
The lipid peroxidation, the total oxidant status and the oxidative stress index were significantly increased in the brain and retina of exposed rats when compared to the control group while the total antioxidant status was significantly decreased. Regarding lipid peroxidation a dose related effect was observed: The values of the 18 kV/m-exposed group were significantly higher than those of the 12 kV/m-exposed group ...
TY - JOUR. T1 - Antioxidants and Lipid Oxidation in Foods - A Critical Appraisal. AU - Adegoke, G. O.. AU - Kumar, Matam Vijay. AU - Gopala Krishna, A. G.. AU - Varadaraj, M. C.. AU - Sambaiah, K.. AU - Lokesh, B. R.. PY - 1998/7/1. Y1 - 1998/7/1. N2 - Lipid oxidation is a process, which results in rancidity and deterioration of fats posing a major problem In food industry and on biological systems. Many synthetic antioxidants are used in food systems to inhibit lipid oxidation. However, the safety concerns about synthetic antioxidants have led to spurt of research on antioxidants from natural resources, particularly those derived from plant sources. Findings from some such studies on potent aromatic plants having good antioxidant potentials should be pooled to be exploited in food as well as in biological system as a safe alternative to synthetic antioxidants. An attempt has been made in the present review to critically appraise the potentials and safety aspects of synthetic and natural ...
On the other hand, vitamin C did not have an effect on mortality and the antioxidant mineral selenium was associated with a nine per cent decrease in all-cause mortality. We could find no evidence to support taking antioxidant supplements to reduce the risk of dying earlier in healthy people or patients with various diseases,​ said Goran Bjelakovic from the Copenhagen Trial Unit at the Copenhagen University Hospital in Denmark. A republishing of last years antioxidant meta-analysis in the prestigious Cochrane Systematic Review​ today looks set to refocus attention on the efficacy of antioxidant supplements, and raise questions over their safety. The meta-analysis was originally published in the Journal of the American Medical Association​ (2007, Vol. 297, pp. 842-857) last year and attracted criticism from both inside and outside of the dietary supplements industry. The authors admit that this report contained errors and corrections were subsequently published in JAMA​ (2008, Vol. ...
Irwin Naturals Anti-Aging Antioxidants 60 Soft-gels Anti-Aging Antioxidants Directions: Take two soft-gels daily with a meal and a full glass of water. The Free Radical Theory of Aging Free radicals are a major contributor to aging. The free radical theory of aging states that the inborn process of aging is caused by the accumulation of free radical damage inside the body. This theory is supported by countless studies and suggests that antioxidants can help neutralize the effects of natural aging.* Boost Your Antioxidant Defense Systems! Anti-Aging Antioxidants is a simple yet powerful way to boost your daily antioxidant intake. This product supplies a broad spectrum of antioxidant-active compounds to protect your body from the harmful effects of free radicals.* Anti-Aging Antioxidants can be used daily or as needed to help fill the nutritional gaps in your diet. Supplement Facts Serving Size 2 Liquid Soft Gels Servings Per Container 30 Vitamin C as Ascorbic Acid 500mg 833%
You have likely heard the term “antioxidant supplements,” but do you know the role that antioxidants play in preventing cardiovascular disease? In fact, according to proponents of antioxidant supplements, antioxidants cannot only prevent cardiovascular disease, but also reverse the damage that often leads to numerous...
Seventytwo Indian barley varieties were screened for their antioxidant activity for 2 years using two antiradical systems Differences in the levels of antioxidant activity in 2 years were obtained but the genotypic differences still remained and a 2fold variability was observed in the antioxidant activity Yeartoyear differences were also obtained when the selected varieties were analyzed for their free and bound phenolic contents Evaluation of the antioxidant activity and phenolic content in the five varieties grown at six different locations revealed that the antioxidant activity and the free phenolics were more influenced by the genotype whereas the bound and the total phenolics were most influenced by the environment After malting no significant changes were observed in the antioxidant activity however a 2fold increase was observed in the total phenolic content which was mainly due to the increase in the level of free phenolics after ...
1. The oxidation of low-density lipoprotein (LDL) is believed to play a central role in atherogenesis. We have compared the effect of antioxidant vitamins and high-density lipoprotein (HDL) on the Cu(2+)-catalysed oxidation of LDL. 2. Antioxidant vitamin supplementation significantly reduced conjugated diene formation but did not affect the formation of lipid peroxides. 3. Conversely, HDL did not affect conjugated diene formation but inhibited the formation of lipid peroxides by up to 90%. 4. The inhibition by HDL of lipid peroxide formation in oxidized LDL was dependent on the concentration of HDL and was not due to HDL chelating Cu2+. 5. Large interindividual variations in the inhibition of lipid peroxide formation by autologous HDL were evident, which were related to the rate of lipid peroxide generation in the LDL. 6. We conclude that HDL is a powerful antioxidant or more probably inhibitor of LDL oxidation in vitro and may play an important role in vivo in preventing atherosclerosis by ...
Hydrogen atom transfer (HAT) is the mechanism by which the vast majority of radical-trapping antioxidants (RTAs), such as hindered phenols, inhibit autoxidation. As such, at least one weak O-H bond is the key structural feature which underlies the reactivity of phenolic RTAs. We recently observed that quinone methi 2020 Chemical Science HOT Article Collection 2020 ChemSci Pick of the Week Collection
Youve seen or heard the term antioxidant before and you feel like its something you should have in your food, right? Right, but you probably dont know what antioxidants actually are and why you need them. I know that was the case for me.. To understand what antioxidants are, you must first know what a free radical is. Free radicals are naturally occurring substances in our bodies that attack the fats, protein and DNA in our cells, causing us to age quickly and can even cause diseases. Antioxidants are the compounds found in some foods that help to neutralize the free radicals in our bodies. The best sources of antioxidants are fruits and vegetables but they are also found in green tea, black tea, red wine and dark chocolate (yum!). According to experts, the presence of color indicates that there is a specific antioxidant in that food.. Now do you understand why we need them? I do! To get a healthy dose of antioxidants in your diet, try eating more of these foods.. Tomatoes ...
Kirkmans Alpha Lipoic Acid is a powerful and versatile nutrient with antioxidant activity that helps protect the body against free radical damage and, as a result, is a protector of many types of cells and tissues. It also helps increase glutathione production, which supports detoxification processes in the body.. Alpha lipoic acid is a nutrient with unique antioxidant activity in that it is both fat- and water-soluble. Other well-known nutrients with antioxidant activity can only function within their soluble media. Because of its dual solubility, alpha lipoic acid can function in both fatty and aqueous parts of a cell and is capable of defending against a wide variety of invading free radicals. Alpha lipoic acid can enter all parts of a nerve cell and also cross the blood-brain barrier and protect cells.. Alpha lipoic acid is found naturally in foods such as spinach, broccoli, tomatoes, liver, heart and animal muscle tissue. Its bioavailability from food may be limited, however, because it is ...
High ORAC food supplements are the latest craze. Find out what ORAC means and its relevance in evaluating supplements. - Oxygen Radical Absorbance Capacity (ORAC) - Holistic Health at BellaOnline
A plant-based diet protects against chronic oxidative stress-related diseases. Dietary plants contain variable chemical families and amounts of antioxidants. It has been hypothesized that plant antioxidants may contribute to the beneficial health effects of dietary plants. Our objective was to develop a comprehensive food database consisting of the total antioxidant content of typical foods as well as other dietary items such as traditional medicine plants, herbs and spices and dietary supplements. This database is intended for use in a wide range of nutritional research, from in vitro and cell and animal studies, to clinical trials and nutritional epidemiological studies. We procured samples from countries worldwide and assayed the samples for their total antioxidant content using a modified version of the FRAP assay. Results and sample information (such as country of origin, product and/or brand name) were registered for each individual food sample and constitute the Antioxidant Food Table. The
Water and lipid soluble antioxidant; supports glucose metabolism and nerve health Alpha lipoic acid is an exceptionally versatile nutrient; being both water and fat soluble, it is able to function in almost any part of the body. It is manufactured in the body, but often times not in the amounts necessary to perform its many functions. Alpha lipoic acid is a potent antioxidant which neutralizes harmful free radicals and enhances the activity of vitamins C and E. A key component of the metabolic process, alpha lipoic acid produces energy in muscles and directs calories into energy production. In addition, this powerful nutrient helps maintain healthy glucose metabolism, supports the nervous system and provides nutritional support for healthy liver function. In one study, alpha lipoic acid decreased serum lactate and pyruvate and promoted healthy glucose metabolism in lean and overweight individuals. Alpha lipoic acid supported nerve health in subjects who participated in a four-month, randomized, double
The in vitro antioxidant potential assay between ethanolic extracts of two species from the genus Vitex (Vitex negundo L. and Vitex trifolia L.) belonging to the Lamiaceae family were evaluated. The antioxidant properties of different extracts prepared from both plant species were evaluated by different methods. DPPH scavenging, nitric oxide scavenging, and β-carotene-linoleic acid and ferrous ion chelation methods were applied. The antioxidant activities of these two species were compared to standard antioxidants such as butylated hydroxytoluene (BHT), ascorbic acid, and Ethylene diamine tetra acetic acid (EDTA). Both species of Vitex showed significant antioxidant activity in all of the tested methods. As compared to V. trifolia L. (60.87-89.99%; 40.0-226.7 μg/mL), V. negundo has been found to hold higher antioxidant activity (62.6-94.22%; IC50 = 23.5-208.3 μg/mL) in all assays. In accordance with antioxidant activity, total polyphenol contents in V. negundo possessed greater phenolic (89.71 mg GAE
Title: 3,4-Dihydrospiro[piperidine-4,2-(1H)quinoline] Derivatives as New Antioxidant Agents with Acetylcholinesterase Inhibitory Property. VOLUME: 7 ISSUE: 10. Author(s):Vladimir V. Kouznetsov, Leonor Y. Vargas Mendez and Amner Munoz Acevedo. Affiliation:Laboratorio de Quimica Organica y Biomolecular, Escuela de Quimica, Universidad Industrial de Santander, A.A. 678 Bucaramanga, Colombia.. Keywords:Antioxidant capacity, AChE inhibitory activity, Intramolecular Friedel-Crafts cyclization, Dihydrospiro[piperidine-4,2(1H)quinoline] derivatives, Multifunctional drug discovery, 4-allyl-4-arylaminopiperidines, AChE assay, Alzheimers disease, AD, tacrine, rivas-tigmine, donepezil, galantamine, acetylcholine, hyperphosphory-lation, tacrine-ferullic hybrids, tacrine-melatonin, TMTHQ, Physostigmine, Trolox, Toluene, Allylmagnesium bromide, H-NMR, C-NMR, TPSA, BHT, 2,6-di-tert-butyl-4-methylphenol, BHA, 2-tert-butyl-4-hydroxyanisol, Trolox® Equivalent Antioxidant Capacity, TEAC, Ellmans reagent, DTNB, ...
Antioxidants can be used on a long-term basis, also after completion of Momentum® Stage 1 and 2. The product is very well-suited to people who smoke, experience stress, are exposed to sun and/ or exercise a lot.. About alpha lipoic acid Momentum® Antioxidant contains a high dose of R-alpha lipoic acid (the natural and most easily absorbed form of alpha lipoic acid). Alpha lipoic acid is a fatty acid which naturally occurs in the human body and in foodstuffs (steak, offal contain alpha lipoic acid). Alpha lipoic acid has two functions: it is essential for cellular energy production and a very powerful antioxidant which renders various free radicals harmless 2-3. Additionally it helps to ensure that previously oxidised antioxidants (such as vitamins C and E) can be returned to their original, active, form. This ensures that these chemicals work even better and that the antioxidative capacity of the body is increased.. Alpha lipoic acid also functions as an anti-inflammatory and helps fight cell ...
Consumption of plant flavonoids, antioxidants, and n-3 fatty acids is proposed to have many potential health benefits derived primarily through antioxidant and anti-inflammatory activities. This study examined the effects of 1,000 mg quercetin + 1,000 mg vitamin C (QC); 1,000 mg quercetin, 1,000 mg vitamin C, 400 mg isoquercetin, 30 mg epigallocatechin gallate, and 400 mg n-3 fatty acids (QFO); or placebo (P), taken each day for 2 wk before and during 3 d of cycling at 57% Wmax for 3 hr, on plasma antioxidant capacity (ferricreducing ability of plasma [FRAP], oxygen-radical absorbance capacity [ORAC]), plasma oxidative stress (F2-isoprostanes), and plasma quercetin and vitamin C levels. Thirty-nine athletes were recruited and randomized to QC, QFO, or P. Blood was collected at baseline, after 2 wk supplementation, immediately postexercise, and 14 hr postexercise. Statistical design used a 3 (groups) × 4 (times) repeated-measures ANOVA with post hoc analyses. Plasma quercetin was significantly ...
Low prices on Alpha Lipoic Acid! Alpha lipoic acid is a powerful antioxidant*. Alpha-lipoic acid (ALA) provides antioxidant protection throughout the body because of its unique property of being both fat and water soluble. It also protects you by helping the body recycle other antioxidants like vitamin C, vitamin E, CoQ10 and glutathione. Alpha lipoic acid helps support normal blood sugar levels already within the normal range.*
The most common and most efficient antioxidants are: Vitamins A, C and E, Carotenoids, Selenium, Alpha Lipoic Acid and Coenzyme Q10.. Antioxidants can be found in food: fruits, vegetables and whole grains, but if your dog does not eat enough of these you should probably consider adding antioxidant supplements to his meals.. It is recommended to consult with your veterinarian and then decide which combination of antioxidants you should administer to your dog according to his age and needs.. ...
TY - JOUR. T1 - Voltammetric study of the antioxidant properties of catalase and superoxide dismutase. AU - Korotkova, E. I.. AU - Lipskikh, O. I.. AU - Kiseleva, M. A.. AU - Ivanov, V. V.. PY - 2008/8. Y1 - 2008/8. N2 - The antioxidant properties of catalase and superoxide dismutase (SOD) have been studied by voltammetry. The effect of pH on the antioxidant properties of catalase and SOD has been evaluated. It is established that the antioxidant activity of both enzymes is maximum at pH 6.86. Mechanisms of the interaction of enzymes with reactive oxygen species are considered. Antioxidant activity criterion (IC50) for SOD and some copper complexes have been estimated by voltammetry and spectrophotometry.. AB - The antioxidant properties of catalase and superoxide dismutase (SOD) have been studied by voltammetry. The effect of pH on the antioxidant properties of catalase and SOD has been evaluated. It is established that the antioxidant activity of both enzymes is maximum at pH 6.86. Mechanisms ...
Product Description wholesale raw material powder r alpha lipoic acid alpha lipoic acid; r alpha lipoic acid; lipoic acid Brief Introduction and Application Product Name: alpha lipoic acid raw material CAS No.: 1077-28-7 Purity: 99%-101% MO
Antioxidant-rich - Cacao is the most antioxidant-rich food in the world. Its powder, for instance, contains an ORAC (Oxygen Radical Absorbance Capacity) score of 95,500 µmol per 100g, while cacao nibs contain a lower but still impressive 62,100 µmol per 100g. To put these numbers in perspective, goji berries (the highest non-cacao source of antioxidants) score 25,300, acai berries score 18,500, and blueberries - famous for their antioxidant content - score 2,400. Many of the antioxidants present in cacao are flavonoids, including anthocyanidin. Like all antioxidants, these flavonoids are intimately involved in the prevention of free radical damage, but they also have a central role in boosting collagen protection. This means that antioxidant-rich foods like cacao are not only good at guarding us from cancer and other degenerative diseases, but also provide us with many anti-aging benefits.. Mood booster - Chocolate, in both its processed and natural form, has always been regarded as a mood ...
In this study, evidence has been collected that supports the notion that paclitaxel may exert its toxicity via elevation of intracellular O2−, H2O2, and NO levels. This theory is confirmed by our data showing that (a) paclitaxel induced the production of O2−, H2O2 and NO; (b) paclitaxel induced oxidative DNA damage; (c) agents that decreased H2O2 and NO production suppressed paclitaxel-induced DNA damage, G2-M arrest, apoptosis, and cell growth inhibition; (d) inhibition of SOD or glutamylcysteine synthase increased paclitaxel-induced apoptosis; (e) cell lines with higher total antioxidant capacity were more resistant to paclitaxel cytotoxicity; and (f) agents that decreased clonogenic survival in paclitaxel-treated cells also decreased cellular total antioxidant capacity. Thus, paclitaxel chemoresistance correlates very well to intracellular antioxidant capacity.. Kong et al. ( 27) speculated that many chemotherapeutic agents exert their toxic effects on cancer cells by producing free ...
D6810-13 Standard Test Method for Measurement of Hindered Phenolic Antioxidant Content in Non-Zinc Turbine Oils by Linear Sweep Voltammetry antioxidant content~ linear sweep voltammetry~ 2,6-di-tert-butylphenol~
This review addresses the general hypothesis that the pathogenesis of preeclampsia and eclampsia are related to an imbalance of increased oxidative stress and lipid peroxidation coupled with a deficiency of antioxidant protection. Accordingly, this study was initiated to assess total antioxidant status and free-radical activity in preeclampsia and eclampsia. The patients studied were 44 healthy pregnant women and 45 women with hypertension classified as having preeclampsia (n=27), and eclampsia (n=18). The serum levels of lipid peroxide were significantly increased (p,0.0001) and antioxidant enzyme activities (superoxide dismutase and glutathione levels) in erythrocytes were significantly decreased (p,0.0001) in women with preeclampsia and eclampsia compared with the controls. The groups of preeclampsia and eclampsia had similar values of catalase activities as the controls (p,0.05). There were no correlations between serum levels of lipid peroxide and antioxidant enzyme activities or ...
The antioxidant activities of five medicinal plants (Ampelopsis sinica, Ampelopsis humiliforlia var. heterophylla, Potentilla freyniana, Selaginella labordei and Chrysanthemum multiflorum), used in the Hubei province of China, have been investigated using both enzymatic and non-enzymatic in vitro antioxidant assays. Extracts from all five of the plants inhibited xanthine oxidase and lipoxygenase activities, and were scavengers of the ABTS*+ radical cation using the Trolox equivalent antioxidant capacity assay (TEAC). Extracts from Potentilla freyniana and Selaginella labordei down-regulated cyclooxygenase-2 gene expression, measured by real-time RT-PCR, in human colon adenocarcinoma CaCo-2 cells.. ...
Previously we have reported that patients with rheumatoid arthritis (RA) obtained a significant reduction in disease activity by adopting a Mediterranean-type diet. The present study was carried out to investigate the antioxidant intake, the plasma levels of antioxidants and a marker of oxidative stress (malondialdehyde) during the study presented earlier. RA patients randomized to either a Mediterranean type diet (MD group; n = 26) or a control diet (CD group; n = 25) were compared during a three month dietary intervention study. Their antioxidant intake was assessed by means of diet history interviews and their intake of antioxidant-rich foods by a self-administered questionnaire. The plasma levels of retinol, antioxidants (α- and γ-tocopherol, β-carotene, lycopene, vitamin C and uric acid) and urinary malondialdehyde (MDA), a marker for oxidative stress, were determined using high performance liquid chromatography. The Students t-test for independent samples and paired samples were used to test
Shop a variety of alpha lipoic acid antioxidant supplements at Vitamin World, to help metabolize sugar, especially in muscles, where it promotes energy.
A team of scientists have designed a synthetic antioxidant, XJB-5-131, that targets mitochondria and suppresses symptoms of Huntingtons disease in mice.. Theres new hope in the fight against Huntingtons disease. A group of researchers that includes scientists from the U.S. Department of Energys Lawrence Berkeley National Laboratory (Berkeley Lab) have designed a compound that suppresses symptoms of the devastating disease in mice.. The compound is a synthetic antioxidant that targets mitochondria, an organelle within cells that serves as a cells power plant. Oxidative damage to mitochondria is implicated in many neurodegenerative diseases including Alzheimers, Parkinsons, and Huntingtons.. The scientists administered the synthetic antioxidant, called XJB-5-131, to mice that have a genetic mutation that triggers Huntingtons disease. The compound improved mitochondrial function and enhanced the survival of neurons. It also inhibited weight loss and stopped the decline of motor skills, ...
If you are looking for something to increase your weight loss efforts and boost your energy while you lose weight, antioxidants can help. The process of losing weight actually releases more free radicals into your body than normal and for this reason, it is vitally important to make sure you are getting an adequate amount of antioxidants to assist with your weight loss.. 2. Antioxidant super-fruits - The new trend in weight loss today seems to be the super-fruits known commonly as acai berries or goji berries. These exotic fruits from far away lands are proven to have relatively high antioxidant content. Comparitively, wolfberry (goji) and acai berry are the highest ranking foods in terms of antioxidant content.. Taking antioxidants regularly will help to make you feel better and reduce illness during your weight loss. You may want to buy a supplement high in antioxidants such as one of the trendy super-fruits, acai and goji berry. To find out more about how you can lose that stubborn fat ...
Background: Chronic renal failure, particularly end-stage renal disease, is a serious health problem associated with a high mortality rate. Uremic syndrome leads to increased oxidative stress, inflammation, and dyslipidemia. Aims: To examine superoxide dismutase isoenzyme gene expression in peripheral blood mononuclear cells of patients on hemodialysis and to determine the associations between superoxide dismutase isoenzyme gene expression, oxidative stress, and non-enzymatic antioxidative protection. Study Design: Case control study. Methods: This study included 33 patients on hemodialysis (age, 55.33 +/- 15.31 years old) and 33 apparently healthy controls (age, 45.37 +/- 8.92 years old). Superoxide dismutase isoenzyme messenger ribonucleic acid levels were determined by real-time polymerase chain reaction. General biochemical parameters, high sensitivity C-reactive protein, total antioxidant status, thiobarbituric acid-reactive substances, and the superoxide anion radical were also ...
Alzheimers disease (AD) is a serious condition associated with increased inflammation, cholesterol, and oxidative stress (a condition involving an excess of free radicals and a decrease in antioxidant levels). Fish oil and alpha lipoic acid, which have few side effects, may help relieve these problems; therefore, these supplements may slow the progression of AD, particularly when given in combination. This study will evaluate the effect of fish oil and alpha lipoic acid on inflammation, lipid levels, and oxidative stress.. Participants in this study will be randomly assigned to receive fish oil alone, fish oil and alpha lipoic acid, or placebo for 1 year. AD rating scales as well as urine and blood tests will be used to assess participants. Participants will have monthly clinic visits during the study to monitor adverse events and to undergo various laboratory tests. ...
Among antioxidants, alpha lipoic acid is unique because it is both fat and water soluble. This means it can work in more areas of the body than other antioxidants that either dissolve in water like Vitamin C or are absorbed into fat like Vitamin E. Alpha lipoic acid has another important role through increasing the…
How do antioxidants work?. Antioxidants perform mainly by taking away totally free radicals, terminating the destructive chain reactions via which these free radicals injury cells. Antioxidants do so by reacting with the free radical, and are as a result used up when they terminate the reaction.. This operate of anti-oxidants explain their exceptional potential to defend the physique in opposition to a wide selection of threats. For illustration, the antioxidant lutein, a carotenoid located in many plants, absorbed into the entire body when we take in these vegetation, is acknowledged to safeguard from radiation hurt: when radiation enters the physique and breaks aside a molecule creating a free radical, lutein neutralizes the free radical, therefore decreasing the volume of radiation injury.. Oxidative tension is associated with many types of ailment, so antioxidants can shield from a wide variety of distinct stressors on the human body.. Examples of antioxidants:. Antioxidants consist of the ...
TY - JOUR. T1 - The protective effect of Opuntia dillenii Haw fruit against low-density lipoprotein peroxidation and its active compounds. AU - Chang, Su Feng. AU - Hsieh, Chiu Lan. AU - Yen, Gow Chin. PY - 2008/1/15. Y1 - 2008/1/15. N2 - The antioxidant activity and inhibitory effect of extracts from Opuntia dillenii Haw fruit (ODHF) and its active compounds on low-density lipoprotein (LDL) peroxidation were investigated. The results indicated that the antioxidant activity of methanolic extracts of ODHF in Trolox equivalent antioxidant capacity and oxygen-radical absorbance capacity assays were in the order of seed , peel , pulp. The lag time of conjugated diene formation in Cu2+-induced LDL oxidation was increased by incubation of LDL with various methanolic extracts of ODHF. The methanolic extracts from seed, peel and pulp prolonged the lag time compared to control (154.1 min) to 514.8, 163.9 and 190.2 min, respectively, at a concentration of 10 μg/ml. Among the extracts, seed extracts of ...
Alpha lipoic acid is a powerful antioxidant that first gained worldwide recognition at the United Nations First Joint Conference on Healthy Aging in 1996. Some of the findings presented at the conference included research that showed that alpha lipoic acid directly restores vitamin C and glutathione to their active fo
Save 50% Lindberg - Alpha Lipoic Acid 100 mg 120 Capsules Alpha Lipoic Acid 100 mg Antioxidant Support* Alpha-Lipoic Acid is involved in the energy-producing reactions in the body. Both fat and water soluble, Alpha-Lipoic Acid supports antioxidant processes both inside the cell and and at the cell membrane level.* It also increases the antioxidant capacity of other nutrients by helping the body recycle vitamins C and E, CoQ10 and glutathione.* Alpha-Lipoic Acid helps support normal blood sugar levels already within the normal range.*
Botanicals have been explored for their multitude of pharmaceutical and therapeutic potential. In this study, crude methanolic extract (MSSL) and organic soluble fractions of Syzygium samarangense leaves were evaluated for antioxidant activity using in vitro and in vivo models. To evaluate the antioxidant activity, total antioxidant capacity, free radical scavenging ability (DPPH) and reducing power, assays were conducted in vitro. Lipid peroxidation and activities of different antioxidant enzymes were measured in vivo. Quantitative phytochemical analyses such as the measurement of total phenolic, flavonoid, flavonol, and proanthocyanide contents were also evaluated. The ethyl acetate fraction (ESSL) showed significant effects in DPPH assay (IC50 = 38.84 ± 0.08 μg/mL) and reducing power assay. The effect of ESSL was found to be concentration-dependent with remarkable antioxidant activity as compared to other tested samples. In addition, administration of the extract/fractions (200 and 400 ...
Natural News) Antioxidants such as vitamin C are often taken to boost immunity and prevent diseases, but these substances can also be used against a water contaminant called hexavalent chromium. This chemical contaminates the water supply in about 200 million American homes.. Researchers from Olivet Nazarene University in Bourbonnais, Illinois discovered that vitamin C and other antioxidants like epigallocatechin gallate (EGCG), the primary antioxidant in green tea, can reduce the harmful effects of hexavalent chromium. This chemical is often produced by industrial processes, so it usually enters the water supply through industrial waste. Additionally, it is known to cause cancer. (Related: Hexavalent chromium (chromium-6) was just found in 75% of drinking water… the mass chemical suicide of America is under way.). In this study, the researchers aimed to determine whether antioxidants can help avoid cell toxicity. To do so, the researchers exposed two types of human cells to different ...
The health benefits of extra virgin olive oil (EVOO) are related with its chemical composition and the presence of bioactive compounds with antioxidant properties. The aim of this study was evaluate antioxidant compounds (pigments, CoQ10 and phenolic compounds) and antioxidant properties of EVOO from the same region comparing different cultivars (Hojiblanca and Arbequina), harvest year and crop stage. Antioxidant properties of oils were studied before and after a gastrointestinal digestion process, by in vitro assays (DPPH, ABTS and FRAP) and antioxidant markers in Caco-2 cells (reactive oxygen species production). The content of bioactive compounds measured was significantly affected by cultivar and harvest year (except for carotenoids) and by the crop stage (except for coenzyme Q10). Higher amount of coenzyme Q10 was observed in Hojiblanca than in Arbequina EVOO. Total phenol content and antioxidant properties were also different depending on cultivar and harvest year and the in vitro digestion
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TY - JOUR. T1 - Use of organotypic cultures of Cortis organ to study the protective effects of antioxidant molecules on cisplatin-induced damage of auditory hair cells. AU - Kopke, Richard D.. AU - Liu, Wei. AU - Gabaizadeh, Ramin. AU - Jacono, Andrew. AU - Feghali, Joseph. AU - Spray, David. AU - Garcia, Phil. AU - Steinman, Howard. AU - Malgrange, Bridgitte. AU - Ruben, Robert J.. AU - Rybak, Leonard. AU - Van De Water, Thomas R.. PY - 1997/9/1. Y1 - 1997/9/1. N2 - Hypothesis: Cisplatin causes the generation of reactive oxygen species (ROS), which interferes with the antioxidant defense system of Cortis organ and results in damage to the hair cells. Background: Cisplatin is a widely used chemotherapeutic agent with the dose-limiting side effect of ototoxicity. Evidence is accumulating that cisplatin interferes with the antioxidant defense system of Cortis organ. Methods: Organotypic explants of P-3 rat organ of Corti were the in vitro model system. Presence of intact auditory hair cells and ...
The potential of selected industrial food wastes from juice and nut production including apple peel, apple pomace, pomegranate peel, pomegranate seed, chestnut shell, and black carrot pomace as resources for natural antioxidants was investigated. Soluble free and insoluble-bound phenolics were extracted from the wastes and analyzed for total phenolic and flavonoid contents, phenolic profile and antioxidant activity. Total phenolic and total flavonoid contents of wastes were positively correlated with their antioxidant activity. The highest total phenolic and antioxidant activity were determined in soluble fraction of pomegranate peel due to a significant amount of punicalagin derivatives. Pomegranate peel and seed had the most phenolics and flavonoids in soluble form while other wastes had more than 45% of total phenolics in insoluble-bound form. Chestnut shell showed more antioxidant activity in insoluble-bound fraction compared to that of its soluble fraction. These findings showed that not ...
Quite Possibly the Universal Antioxidant. Lester Packer, Ph.D., of the University of California, Berkeley, published a lengthy review article on alpha-lipoic acid in Free Radical Biology & Medicine. Several qualities distinguish alpha-lipoic acid from other antioxidants, and Packer has described it at various times as the universal, ideal, and metabolic antioxidant. It directly recycles and extends the metabolic life spans of vitamin C, glutathione, and coenzyme Q10, and it indirectly renews vitamin E.. Alternative Names: Thiotic Acid or Thioctic Acid, Lipoic Acid, ALA. Alpha lipoic acid is a fatty acid found naturally inside every cell in the body. Its needed by the body to produce the energy for our bodys normal functions. Alpha lipoic acid converts glucose (blood sugar) into energy.. Alpha lipoic acid is an antioxidant; a substance that neutralizes potentially harmful chemicals called free radicals. What makes alpha lipoic acid unique is that it functions in water and fat, unlike ...
Alpha-lipoic acid helps prevent certain kinds of cell damage in the body. It also restores vitamin levels such as vitamin E and vitamin C in their cycles so they would work again as an antioxidant in their cycles and this reduces body need of antioxidants. There are some evidence that alpha-lipoic acid can improve the function and conduction of neuron cells in diabetes. ALA antioxidant benefits might also be helpful in liver diseases. ...
Buy Alpha Lipoic Acid 300 mg 60 Capsules & other Antioxidants Supplements. Alpha Lipoic Acid (ALA) serves a variety of important functions in the body, one of which is the ability to help metabolize sugar, especially in muscles, where it promotes energy.
Table 3: Tai Chi Exercise Increases SOD Activity and Total Antioxidant Status in Saliva and Is Linked to an Improvement of Periodontal Disease in the Elderly
Some nutrients play a supporting role. For instance, selenium is an essential component of various enzymes used by the antioxidant network. And flavonoids help recycle vitamin C.. The mineral selenium is not an antioxidant but it supports the network antioxidants. For example, it works in synergy with vitamin E, making a powerful combination. Selenium is also an essential component in various enzymes used by the antioxidant network, including glutathione peroxidase and thioredoxin reductase, which reactivates and recycles vitamin C.. Selenium is involved in the antioxidant enzymes responsible for detoxifying rancid fat in membranes. Also, with seleniums help, vitamin E protects lipoproteins against oxidative damage more effectively.. Blood platelets contain the greatest concentration of selenium of any body tissue, suggesting that high levels of selenium may prevent blood clots. This network helpers role in heart disease prevention is complex but numerous studies have linked low consumption of ...
Free Radicals and Antioxidants [ISSN: 2231-2536] is an online peer reviewed publication dedicated to publishing novel, original findings in the field of free radical biology and both natural and synthetic antioxidants. The Free Radicals and Antioxidants Journal aims to foster the dissemination of scientific information by publishing manuscripts that provide new insights into the biology of free radicals, including their generation, degradation, modulation, role in cellular function and cell signaling. The submission of uninvited expert reviews and research articles in all areas of Free Radical Biology and Antioxidants are also welcomed. Free Radicals and Antioxidants publishes full research papers presenting original, high quality research, critical review articles providing comprehensive analysis of research development within a defined area and editorial commentaries on key topical issues in Free Radical and Antioxidant Biology.. ...
Buy Resveratrol 250 mg plus Red Wine Extract 60 Rapid Release Softgels & other Antioxidants Supplements. Resveratrol is the beneficial nutrient in red wine. Provides powerful antioxidant support & helps fight against cell-damaging free radicals.
Antioxidants are an important substance that can fight the deterioration of free radicals and can easily oxidize when exposed to light. There are many methods to measure the antioxidant activity in a biological sample, for example 2,2-diphenyl-1-picrylhydrazyl (DPPH) antioxidant activity test, which is one of the simplest methods used. Despite its simplicity, the organic solvent that has been used to dilute DPPH is easily evaporated and degraded with respect to light exposure and time. Thus, it needs to be used at the earliest convenient time prior to the experiment. To overcome this issue, a rapid and close system for antioxidant activity is required. In this paper, we introduced the Lab-on-a-Disc (LoD) method that integrates the DPPH antioxidant activity test on a microfluidic compact disc (CD).We used ascorbic acid, quercetin, Areca catechu, Polygonum minus, and Syzygium polyanthum plant extracts to compare the results of our proposed LoD method with the conventional method. Contrasted to the ...