In this study, we determined serum aminopeptidase N/CD13 concentrations in patients with NSCLC using an aminopeptidase N/CD13-specific mAb (MH8-11), which inhibits cell motility and angiogenesis in vitro (10). Serum aminopeptidase N/CD13 concentrations were significantly elevated in patients with advanced-stage NSCLC. When the serum aminopeptidase N/CD13 values corresponding to the best diagnostic accuracy to separate the healthy controls and the patients with NSCLC were used as the cutoff value, the sensitivity of aminopeptidase N/CD13 was poorer than that of serum carcinoembryonic antigen; this suggests that serum aminopeptidase N/CD13 is not valuable as a diagnostic marker. However, a high serum aminopeptidase N/CD13 was significantly associated with established adverse prognostic factors in NSCLC, such as advanced stage, poor performance status, and poor response to chemotherapy. Serum aminopeptidase N/CD13 levels were also associated with overall survival in univariate analyses and had an ...
HUMAN coronaviruses (HCV) in two serogroups represented by HCV-229E and HCV-OC43 are an important cause of upper respiratory tract infections1. Here we report that human aminopeptidase N, a cell-surface metalloprotease on intestinal, lung and kidney epithelial cells2-5, is a receptor for human coronavirus strain HCV-229E, but not for HCV-OC43. A monoclonal antibody, RBS, blocked HCV-229E virus infection of human lung fibroblasts, immunoprecipitated aminopeptidase N and inhibited its enzymatic activity. HCV-229E-resistant murine fibroblasts became susceptible after transfection with complementary DNA encoding human aminopeptidase N. By contrast, infection of human cells with HCV-OC43 was not inhibited by antibody RBS and expression of aminopeptidase N did not enhance HCV-OC43 replication in mouse cells. A mutant aminopeptidase lacking the catalytic site of the enzyme did not bind HCV-229E or RBS and did not render murine cells susceptible to HCV-229E infection, suggesting that the virus-binding site may
Aminopeptidase N (Myeloid Plasma Membrane Glycoprotein CD13 or Alanyl Aminopeptidase or Aminopeptidase M or Microsomal Aminopeptidase or gp150 or CD13 or ANPEP or EC 3.4.11.2) - Market research report and industry analysis - 11296626
Aminopeptidase N (APN)/CD13 as ubiquitously expressed membrane peptidase exerts important functions in diverse cellular processes, such as proliferation, migration and differentiation. Previously, a role of APN in the invasiveness of melanoma cells has been demonstrated, but the underlying molecular mechanisms controlling APN expression are not understood. The present study demonstrates that lack of APN expression in primary and established melanoma cells was directly associated with a high-grade DNA methylation status of the myeloid APN promoter. Demethylation by 5-aza-2-desoxycytidine not only induced constitutive and cytokine-regulated APN protein expression but also resulted in an increased APN-dependent migration of melanoma cells. Furthermore, its heterogeneous expression was inversely correlated to the expression of melanocytic marker proteins in established as well as in short-term cultured human melanoma cells. Staining of tissue microarrays generated from a large series of melanoma ...
Mouse Monoclonal Anti-Aminopeptidase N/CD13 Antibody (CC81) [DyLight 488]. Validated: Flow. Tested Reactivity: Bovine. 100% Guaranteed.
Assay plate (12 x 8 coated Microwells), Standard (Freeze dried), Biotin-antibody (60 x concentrate), HRP-avidin (20 x concentrate), Biotin-antibody Diluent, HRP-avidin Diluent, Sample Diluent, Wash Buffer (20 x concentrate), TMB Substrate, Stop Solution, Adhesive Strip (For 96 wells), Instruction manual ...
Membrane alanyl aminopeptidase (EC 3.4.11.2) also known as alanyl aminopeptidase (AAP) or aminopeptidase N (AP-N) is an enzyme that in humans is encoded by the ANPEP gene. Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, ...
Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract ...
The IUPHAR/BPS Guide to Pharmacology. Leucyl-cysteinyl aminopeptidase - M1: Aminopeptidase N. Detailed annotation on the structure, function, physiology, pharmacology and clinical relevance of drug targets.
CD13/aminopeptidase N (APN), which is a zinc-dependent metalloproteinase, plays a vital role in the growth, migration, angiogenesis, and metastasis of tumours. Thus, in situ molecular imaging of endogenous APN levels is considerably significant for investigating APN and its different functions. In this study 2018 Chemical Science HOT Article Collection
Studies have come to conflicting conclusions about whether adiponectin (APN) expression is associated with cancer prognosis. To help resolve this question, we meta-analyzed the available evidence. PubMed, EMBASE, the Cochrane Library, the Chinese Biological Medical Database and the Chinese National Knowledge Infrastructure Database were systematically searched to identify all eligible studies examining APN expression and prognosis for patients with any type of cancer. Pooled hazard ratios (HRs) and corresponding 95 % confidence intervals (CIs) related to overall survival (OS) or disease-free survival (DFS) were calculated. Ten studies involving 999 patients were meta-analyzed. Analysis across all patients revealed no significant association between high/positive APN expression and DFS, but they did show a significant association between high/positive APN expression and OS (HR 1.51, 95 %CI 1.21 to 1.89). Subgroup analysis showed that high/positive APN expression in non-Asians was significantly associated
In the human T-cellline H9 a neutral aminopeptidase activity was detected that appeared to be distinguished from other known aminopeptidases with respect to its biochemical characterisation. The aim of this work was to identify this enzyme and to subject it to comprehensive biochemical characterization. The enzyme was purified to homogeneity by the application of a number of conventional chromatographic methods and identified by means of mass spectrometry (Maldi TOF) as cytosol alanyl aminopeptidase (EC 3.4.11.14; cAAP, PSA). The biochemical characteristics of the H9 cell-derived peptidase revealed similarities to the corresponding enzyme of other tissues, however, substantial differences have been found out. Apparently, due to these tissue-specific differences there have been assigned different names to this enzyme before. The cytosolic alanyl aminopeptidase showed high sensitivity to inhibitors that have been regarded as specific for the membrane-bound aminopeptidase N (APN): Phebestin, ...
The invention relates to the use of inhibitors of dipeptidyl peptidase IV DP IV and enzymes having the same specific nature of substrate DP IV enzyme activitycombined with inhibitors of alanyl aminopeptidase aminopeptidase N, APNor enzymes having the same specific nature of substrate APN enzyme Try the new Google Patents, with machine-classified Google Scholar results, and Japanese and South Korean patents.. Combined use of enzyme inhibitors for the treatment and prevention of allergic reactions of type i according to the gell and coombs classification, and for the treatment and prevention of dermatological diseases associated with follicular kostengünstige Sprays bei Psoriasis epidermal hyperkeratosis and reinforced keratinocyte proliferation EP B1. The invention kostengünstige Sprays bei Psoriasis to the use of inhibitors of dipeptidyl peptidase IV DP IV and enzymes having the same specific nature of substrate DP IV enzyme activitycombined with inhibitors of alanyl aminopeptidase ...
Després de la bona acollida assolida amb Verkami del 1r cd de Cançons des del mòbil, ara és el moment de recollir les noves cançons al 2n cd
Anpep - mouse gene knockout kit via CRISPR, 1 kit. |dl||dt|Kit Component:|/dt||dd|- |strong|KN301326G1|/strong|, Anpep gRNA vector 1 in |a href=http://www.origene.com/CRISPR-CAS9/Detail.
Aminopeptidase with broad substrate specificity to several peptides. Shows strong preference for leucine but cleaves also next to Arg and lysine in peptide-bond-containing substrates.
To determine the primary structure of CD13, a 150-kD cell surface glycoprotein originally identified on subsets of normal and malignant human myeloid cells, we isolated the complete sequences encoding the polypeptide in overlapping complementary DNA (cDNA) clones. The authenticity of our cDNA clones …
The graphic displays domains and Protease cut sites on the protein sequence. Drag your mouse right/left over the graphic. Use the selection boxes on the right to select which annotations to view simultaneously. Combine annotation with multiple checkmarks.. ...
Use Bio-Rads PrimePCR assays, controls, templates for your target gene. Every primer pair is optimized, experimentally validated, and performance guaranteed.
Summary The pepN gene has been cloned into the multicopy plasmid pBR322. The restriction map of the insert was established and the gene was localized. By comparison with the restriction map of the plasmid pJP30 bearing the ompF region, it has been possible to order the ompF, asnS, and pepN genes.... mehr ...
In addition to their well characterized effects at dopamine receptors, neuroleptic drugs have been shown to affect the level and in vitro metabolism of neuropeptides. In the present study, the effect of acute and subchronic administration of the neuroleptic haloperidol and the nonselective, dopamine agonist apomorphine on neuropeptidase activity was determined in regional, rat brain P2 membranes. Subchronic administration of haloperidol decreased the activity of aminopeptidase N in the frontal cortex and caudate-putamen. In contrast, subchronic administration of apomorphine increased aminopeptidase N activity in the frontal cortex and caudate-putamen. Neutral endopeptidase 24.11 also was affected differentially in the caudate-putamen, but both subchronic haloperidol and apomorphine decreased neutral endopeptidase 24.11 activity in the frontal cortex. Metalloendopeptidase 24.15 activity was decreased in the caudate-putamen after acute haloperidol and increased in the frontal cortex after acute ...
F4⁺ enterotoxigenic Escherichia coli (ETEC) strains cause diarrheal disease in neonatal and post-weaned piglets. Several different host receptors for F4 fimbriae have been described, with porcine aminopeptidase N (APN) reported most recently. The FaeG subunit is essential for the binding of the three F4 variants to host cells. Here we show in both yeast two-hybrid and pulldown assays that APN bind ...
Zhao M, Yuan X, Wei J, et al. Functional Roles Of Cadherin, Aminopeptidase-N And Alkaline Phosphatase From Helicoverpa Armigera (Hübner) In The Action Mechanism Of Bacillus Thuringiensis Cry2Aa[J]. Scientific Reports, 2017.
Acétylmuramyl Alanyl Isoglutamine; acetylmuramyl alanyl isoglutamine; alanyl isoglutamine, acetylmuramyl; dipeptide, muramyl; isoglutamine, acetylmuramyl alanyl; mur nac l ala d isogln; muramyl dipeptide; mur-nac-l-ala-d-isogln; n acetyl muramyl l alanyl d glutamic alpha amide; n acetylmuramyl l alanyl d isoglutamine; n-acetyl-muramyl-l-alanyl-d-glutamic-alpha-amide; n-acetylmuramyl-l-alanyl-d-isoglutamine. Aide pour diagnostic médical. Méthode automatique dassociations de symptômes pour classifier les plus de 4.000 maladies en quatre langues différentes
The objective of this study was to determine rabbit seminal plasma enzyme activity. Furthermore, correlations between semen parameters and enzyme activity and male age were examined. The study was performed using 17 New Zealand White males from 5 to 9 mo old. Overall, 252 semen samples were collected from bucks from May to September. Semen characteristics were analysed and the seminal plasma was obtained by centrifugation. The activities of alanyl aminopeptidase (APN), aspartate transaminase (AST), alanine aminotransferase (ALT), gamma-glutamyl transpeptidase (GOT), lactate dehydrogenase (LDH) and alkaline phosphatase (ALKP) in the seminal plasma fluid were measured. Significant differences between males were found in APN, GGT, LDH, ALKP and ALT activities (P<0.05). No significant differences between enzyme activity and male age were found. We also observed significant positive correlations between male age and sperm concentration (r=0.26), progressive motility (r=0.17) and amplitude of ...
Melflufen (melphalan flufenamide, previously designated J1) is an anticancer drug under development by Oncopeptides AB. It is a peptidase enhanced cytotoxic (PEnC) that exerts a targeted delivery of melphalan in cells with high expression of aminopeptidases, such as aminopeptidase N, which has been described as over-expressed in human malignancies. Aminopeptidase N plays a functional role in malignant angiogenesis. Currently, melflufen is under evaluation in a multinational and randomized phase III study for the treatment of patients with relapsed and refractory multiple myeloma. Melflufen is metabolized by aminopeptidase hydrolysis and by spontaneous hydrolyisis on N-mustard. Its biological half-life is 10 minutes in vitro. Melflufen is a peptidase enhanced cytotoxic (PEnC) with a targeted delivery within tumor cells of melphalan, a widely used classical chemotherapeutic belonging to a group of alkylating agents developed more than 50 years ago. Substantial clinical experience has been ...
The co-distribution of SFN with APN at the leading edge of fibroblasts was unpredicted. Interestingly, an in vitro wound scratch assay revealed higher expression of APN within the migratory fibroblasts, where it co-distributed with vinculin, a migration marker (Lai et al., 2010). In addition, the inhibition of cell migration by reducing or blocking APN levels in tumor cells, lymphocytes and endothelial cells has also been reported (Terauchi et al., 2007; Proost et al., 2007). Therefore, the higher expression of APN receptor at the leading edge of migratory cells could explain the enhanced co-distribution results observed with biotin-SFN. Furthermore, the movement of cells through ECM is highly dependent on the activity of proteases such as MMPs (Gianneli et al., 1997; Kessenbrock et al., 2010; Pilcher et al., 1997; Pirila et al., 2003). This raises the possibility that SFN interaction with APN and the subsequent increase in MMP-1 activity could play a role in the cell migration of ...
Prices are in US dollars.. These products are for laboratory research purposes only, not for any human or animal diagnostic or therapeutic use.. All site content © 2017 Cell Sciences, Inc.. ...
Prices are in US dollars.. These products are for laboratory research purposes only, not for any human or animal diagnostic or therapeutic use.. All site content © 2017 Cell Sciences, Inc.. ...
CHAPTER LXXVIII. 203 Jh 4^ !j3 .2-^ aS-: 04g what mon fal ames vish ^ 0 w CD -^ a-c i^, w-w Uesckiption of the Single VISHTIS. -c; .£ Ti fO N CD o3 rc; ■^ t+H 0 c3 f,, A cS ^ OJ -C 4J Pi 1-1 It is white, has three eyes, and rides on an elephant, which always remains the same. In the one hand he has a huge rock, in the other a vajra of iron, which it throws. It destroys the cattle over which it rises. He who makes war coming from the direction whence it rises will be victorious. A man must not turn with his face towards it when tearing out fattening herbs, digging out treasures, and trying to satisfy the wants of life. It has the colour of crystal. In one hand it holds a three¬ fold parasvadha, and in the other a rosary. It looks towards heaven, and saj^s hd hd hd. It rides on an ox. Its time is favourable for handing over the chil¬ dren to the schools, for con¬ cluding peace, giving alms, and works of piety. ■Sg2 si osq It is pistachio-coloured like a parrot. It looks like ...
Aerobic activity іѕ аnу activity thаt requires сlеаn air tο produce thе nесеѕѕаrу ATP (adenosine triphosphate) tο carry out thе activity. Aerobic work out activity gets ATP through thе Krebs Design. Once through thе Krebs pattern generates 36 ATPs compared tο јυѕt 2 ATP through glycolysis οr anaerobic pattern. Aerobic work out activity іѕ essential fοr уουr center health.. Aerobic activity achieves thе following:. 1. Increases уουr VO2 max (уουr maximum сlеаn air uptake). It dοеѕ thіѕ bу helping thе quality οf сlеаn air уουr human іѕ аblе tο υѕе during regular aerobic work out activities. If уουre out οf shape аnd rυn a range, уου mіght rυn іt іn ten minutes οr ѕο, bυt іf уου hаνе a regular aerobic workout routine (whісh сουld involve operating, walking, managing, driving, οr аnу center activity), уου саn speed up managing thе range bу minutes bесаυѕе уουll bе breathing more ...
CD13, also known as aminopeptidase N, APN and gp150, is a 150-170 kDa transmembrane ectoenzyme occurring on monocytes and granulocytes but not lymphocytes in blood.
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A story: In the mid-1990s, I participated inside a PSA guideline group for Malignancy Care Ontario. The usual literature search was carried out, which focused on the evidence of mortality benefit and the potential harms of screening. I have been building decision types of PSA testing2 and measuring quality-of-life and price results for a long time. I was somewhat chagrined that non-e of my documents resulted in in the search. I had been created by it question, So why will be the remaining committee and We viewing this nagging issue thus differently? My model recommended that there could be a mortality advantage but general a lack of quality-adjusted life span. This meant that the true manner in which patients valued health outcomes was an integral area of the testing decision. Quite simply, this is a preference-sensitive decision. Furthermore, it seemed as well obvious to say that price was another concern Mouse monoclonal to CD13.COB10 reacts with CD13, 150 kDa aminopeptidase N (APN). CD13 is ...
Opiorfin je endogeno hemijsko jedinjenje koje je prvo izolovano iz ljudske pljuvačke. Inicijalna istraživanja na miševima su pokazala da ovo jedinjenje ima veći analgetski efekat od morfina. Opiorfin deluje putem zaustavljanja normalnog razlaganja prirodnih analgetskih opioida u kičmenoj moždini, zvanih enkefalini. On je relativno mali peptid koji se sastoji od pet aminokiselina: Gln-Arg-Phe-Ser-Arg.[1][2][3][4][5][6][7][8] Opiorfin pentapetid potiče od N-terminalnog regiona proteina PROL1 (prolinom bogat, lakrimal 1).[1] Opiorfin inhibira dve proteaze: neutralnu ekto-endopeptidazu (MME) i ekto-aminopeptidazu N (ANPEP).[1] ...
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3-Fluoro-DL-tyrosine can be used to study how halogenated tyrosines affect proteins such as bacteriorhodopsin, microvillar enzymes, and β-galactosidases.
The pig intestinal brush border enzymes aminopeptidase N (EC 3.4.11.2) and lactase-phlorizin hydrolase (EC 3.2.1.23-62) are present in the microvillar membrane as homodimers. Dimethyl adipimidate was used to cross-link the two [35S]methionine-labeled brush border enzymes from cultured mucosal explants. For aminopeptidase N, dimerization did not begin until 5-10 min after synthesis, and maximal dimerization by cross-linking of the transient form of the enzyme required 1 h, whereas the mature form of aminopeptidase N cross-linked with unchanged efficiency from 45 min to 3 h of labeling. Formation of dimers of this enzyme therefore occurs prior to the Golgi-associated processing, and the slow rate of dimerization may be the rate-limiting step in the transport from the endoplasmic reticulum to the Golgi complex. For lactase-phlorizin hydrolase, the posttranslational processing includes a proteolytic cleavage of its high molecular weight precursor. Since only the mature form and not the precursor of this
Porcine deltacoronavirus (PDCoV), can be an emerging enteropathogenic coronavirus in pigs, that poses a novel threat to swine husbandry worldwide. contamination (Godet et al., 1994) and in severe acute respiratory syndrome coronavirus (SARS-CoV) in the genus (Li et al., 2005). In contrast, the RBD regions of murine hepatitis computer virus and bovine coronavirus, both in the genus are located in the N-terminus of the S1 domain name (Peng et al., 2011, 2012). However, the immunodominant neutralizing region associated with delta-CoVs, such as PDCoV, has not been identified. Recent elucidation of PDCoV spike protein structures by cryo-electron microscopy reveal that this S1 subunit consists of four independently folded domains, specified A, B, C, and D (Xiong et al., 2018). Lately, Li et al. (Li et al., 2018) confirmed the fact that porcine aminopeptidase N, previously regarded as an operating receptor for transmissible gastroenteritis pathogen (TGEV), also interacts using the B area of PDCoV S1 ...
The property of solutions of Triton X-114 to separate into detergent-rich and detergent-poor phases at 30 degrees C has been exploited to investigate the identities of the aminopeptidases in synaptic membrane preparations from pig striatum. When titrated with an antiserum to aminopeptidase N (EC 3.4.11.2), synaptic membranes solubilized with Triton X-100 revealed that this enzyme apparently comprises no more than 5% of the activity releasing tyrosine from [Leu]enkephalin. When assayed in the presence of puromycin, this proportion increased to 20%. Three integral membrane proteins were fractionated by phase separation in Triton X-114. Aminopeptidase activity, endopeptidase-24.11 and peptidyl dipeptidase A partitioned predominantly into the detergent-rich phase when kidney microvillar membranes were so treated. However, only 5.5% of synaptic membrane aminopeptidase activity partitioned into this phase, although the other peptidases behaved predictably. About half of the aminopeptidase activity in ...
To analyze the influence of cell differentiation and the effects of hormones on the subcellular distribution of apical antigens in polarized epithelial cells, we have compared the localization of three brush border (BB) hydrolases [neutral endopeptidase (ENDO), aminopeptidase N (APN), and dipeptidyl …
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The E-Lib is a centralized database of information on APN projects and related outputs. It contains metadata and outputs of all completed and ongoing APN projects since 1998, as well as APN publications such as the Science Bulletin, books, proceedings, reports and policy briefs, etc.
If you are interested in phonographs, gramophones and the history of recorded sound, then the Canadian Antique Phonograph Society (CAPS) is for you. This site provides a glimpse of the Societys programs and activities, and highlights from its bi-monthly publication Antique Phonograph News (APN).
The present invention relates to isolated polypeptides having aminopeptidase activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the polypeptides.
cytosol, aminopeptidase activity, identical protein binding, manganese ion binding, metalloexopeptidase activity, peptidase activity, protein homotetramerization
The protein encoded by this gene is an aminopeptidase which prefers acidic amino acids, and specifically favors aspartic acid over glutamic acid. It is thought to be a cytosolic protein involved in general metabolism of intracellular proteins. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016 ...
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Analysis of Antimalarial Synergy between Bestatin and Endoprotease Inhibitors Using Statistical Response-Surface Modelling: The pathway of hemoglobin degradatio
Pelatihan PONEK - Pelatihan FKTP - Pelatihan MFK - Pelatihan PPGDON - Pelatihan APN - Pelatihan IPCN - Pelatihan Geriatri - Pelatihan Asesor - Pelatihan Case Manajer - Pelatihan Clinical Pathway. Pelatihan PONEK 2020, Pelatihan PONED 2020, Pelatihan Keperawatan 2020, Pelatihan Asesor Perawat, Pelatihan Asesor Bidan, Pelatihan Geriatri 2020, Pelatihan PPI 2020, Pelatihan IPCD 2020, Pelatihan MFK, Pelatihan Asesor Keperawatan, Pelatihan Asesor Bidan 2020, Pelatihan Geriatri, Pelatihan PPI, Pelatihan IPCD, Pelatihan IPCN, Pelatihan Humas Dan Marekting Rumah Sakit, Pelatihan ANJAB, Pelatihan PMKP, Pelatihan HIV Dan AIDS, Pelatihan FKTP, Pelatihan EWS, Pelatihan IPAL, Pelatihan, Pelatihan Kredensial Rumah Sakit, Pelatihan Case Manager, Pelatihan Clinical Pathway, Pelatihan Arsip Elektronik Rumah Sakit, Pelatihan Arsip Elektronik Pemda, Pelatihan Gerontik, Pelatihan APN, Pelatihan HDP, Pelatihan K3 Rumah Sakit, Pelatihan Koding, Pelatihan Gizi Rumah Sakit, Pelatihan Kepala Bidang Keperawatan, ...
Pelatihan PONEK - Pelatihan FKTP - Pelatihan MFK - Pelatihan PPGDON - Pelatihan APN - Pelatihan IPCN - Pelatihan Geriatri - Pelatihan Asesor - Pelatihan Case Manajer - Pelatihan Clinical Pathway. Pelatihan PONEK 2020, Pelatihan PONED 2020, Pelatihan Keperawatan 2020, Pelatihan Asesor Perawat, Pelatihan Asesor Bidan, Pelatihan Geriatri 2020, Pelatihan PPI 2020, Pelatihan IPCD 2020, Pelatihan MFK, Pelatihan Asesor Keperawatan, Pelatihan Asesor Bidan 2020, Pelatihan Geriatri, Pelatihan PPI, Pelatihan IPCD, Pelatihan IPCN, Pelatihan Humas Dan Marekting Rumah Sakit, Pelatihan ANJAB, Pelatihan PMKP, Pelatihan HIV Dan AIDS, Pelatihan FKTP, Pelatihan EWS, Pelatihan IPAL, Pelatihan, Pelatihan Kredensial Rumah Sakit, Pelatihan Case Manager, Pelatihan Clinical Pathway, Pelatihan Arsip Elektronik Rumah Sakit, Pelatihan Arsip Elektronik Pemda, Pelatihan Gerontik, Pelatihan APN, Pelatihan HDP, Pelatihan K3 Rumah Sakit, Pelatihan Koding, Pelatihan Gizi Rumah Sakit, Pelatihan Kepala Bidang Keperawatan, ...