Antifreeze protein from an Antarctic fish [ PDB file ] [ PubMed link ] Many animals that live in extremely cold climates produce proteins that act to prevent the formation of ice crystals in the bodily fluids of the organism. Antarctic fish produce a range of such proteins, as the water temperatures can drop below 0 degrees Celsius. We have determined the structure of the type I antifreeze protein (SS3) from the blood of the shorthorn sculpin at both 5 degrees and -5 degrees. The structure largely comprises a long alpha-helix that displays conserved Thr residues (red) along a single surface. These residues are important for preventing the growth of ice crystals, although the mechanism of action is not currently understood. An additional short helix exists at the N-terminus of the protein, although the conformational relationship between the two helices is not well defined. This is the first solution structure of a wild-type type I antifreeze protein ...
Effect of Antifreeze Proteins on the Nucleation, Growth, and the Memory Effect during Tetrahydrofuran Clathrate Hydrate Formation
Snailfish: Snailfish, any of about 115 species of marine fish often placed with the lumpsuckers in the family Cyclopteridae, but sometimes separated as a distinct family, Liparidae (order Scorpaeniformes). Snailfish are small, growing to a maximum length of about 30 centimetres (12 inches). They are
43. Liparis latifolia Lindley, Gen. Sp. Orchid. Pl. 30. 1830. 宽叶羊耳蒜 kuan ye yang er suan Malaxis latifolia Blume, Bijdr. 393. 1825, not Smith (1812); Cestichis latifolia (Lindley) Pfitzer; Leptorkis latifolia (Lindley) Kuntze; Stichorkis latifolia (Lindley) Pfitzer.. Herbs, epiphytic. Pseudobulbs somewhat densely arranged, subterete, narrowed toward apex, to 8 × 1.5-3 cm, base with reddish brown sheaths. Leaf 1, subelliptic or elliptic-oblong, ca. 20 × 5 cm, base contracted into a petiole, articulate, apex subacuminate. Inflorescence nearly as long as leaf; rachis many flowered; floral bracts small. Flowers pale yellow, lip orange-brown; pedicel and ovary ca. 1.5 cm. Sepals suboblong, ca. 8 × 3 mm, apex acute or obtuse. Petals narrowly linear, ca. 8 × 1 mm; lip subobovate-oblong, ca. 10 × 3 mm, deeply bilobed, with a bilobed basal callus; apical lobes divergent, suboblong, 4-5 × 2.5-3 mm, apex irregularly toothed. Column 3-3.5 mm, upper part with narrow wings. Fl. unknown. 2n = ...
Orchids in the genus Liparis are terrestrial, lithophytic or epiphytic herbs, usually with one to a few leaves which may be linear to egg-shaped, thin or leathery and sometimes pleated. The flowers are small to medium sized, resupinate and arranged on a flowering stem with small bracts. The flowers are usually dull yellow, yellow-green or purplish and often have an unpleasant odour. The sepals and petals turn downwards and the dorsal sepal is free but the lateral sepals are sometimes fused for at least part of their length. The petals are free from each other and often different in size and shape from the sepals. The labellum is usually larger than both the sepals and petals, often lobed with a toothed or wavy edge and one or two calli at its base. There are two pairs of waxy, oval pollinia, each with a viscidium.[4][5][6] ...
Dorsal spines (total): 0; Dorsal soft rays (total): 59; Anal spines: 0; Anal soft rays: 52; Vertebrae: 65. Caudal-fin rays 8; pectoral fin deeply notched, pectoral girdle with 4 round radials, one rudimentary fenestra present; about 7 anterior epineural and epipleural ribs long, stout; chin pores in common wide-oval depression, interspace equals twice their diameter; pectoral without rudimentary notch rays; prominent costal ridge present; head 21% SL, wide (67% HL); eye diameter half interorbital width; preanal length 34% SL; color light-nut-brown, skin semitransparent, peritoneum black (Ref. 42734). ...
J. Huchette, Lubin, M., and Petra, C. G., "Parallel Algebraic Modeling for Stochastic Optimization", HPTCDL 14. IEEE, New Orleans, LA, pp. 29-35, 2014. ...
Antifreeze proteins (AFPs) aid the survival of cold-adapted organisms by inhibiting the growth of ice crystals in the organism. The binding of AFPs to ice separates the melting point from the freezing point of the ice crystal (thermal hysteresis, TH). Although AFPs were discovered more than 40 years ago, the mechan
[106 Pages Report] Check for Discount on Global Antifreeze Proteins (AFP) Sales Market Report 2017 report by QYResearch Group. In this report, the global Antifreeze Proteins (AFP) market is...
Self Bias Resistor writes: According to an article in New Scientist, an antifreeze protein naturally produced by Antarctic fish has been synthesised by U.S. researchers at the University of California. Apparently, this discovery could have a wide variety of applications such as frost-resistant con...
This report describes the use of several isosteric non-natural nucleotides as probes to evaluate the roles of nucleobase shape, size, solvation energies, and π-electron interactions as forces influencing key kinetic steps of the DNA polymerization cycle. Results are provided using representative high- and low-fidelity DNA polymerases. Results generated with the E. coli Klenow fragment reveal that this high-fidelity polymerase utilizes hydrophobic nucleotide analogues with higher catalytic efficiencies compared to hydrophilic analogues. These data support a major role for nucleobase desolvation during nucleotide selection and insertion. In contrast, the low-fidelity HIV-1 reverse transcriptase discriminates against hydrophobic analogues and only tolerates non-natural nucleotides that are capable of hydrogen-bonding or π-stacking interactions. Surprisingly, hydrophobic analogues that function as efficient substrates for the E. coli Klenow fragment behave as noncompetitive or uncompetitive ...
New Roles of Antifreeze Proteins - Antifreeze Proteins as Highly Effective Additives to Control the Crystallization of Non-Ice like Compounds Antifreeze Protein Enhancers: Identification and Mechanisms Effects of Toxic Metal Ions on Zinc Finger Proteins Collaborators Funding
Advances in single-cell technologies have revealed vast differences between cells once thought to be in the same category, calling into question how we define cell type in the first place ...
More than a dozen researchers voice their concerns about a 2010 paper that claims bacteria can use arsenic in place of phosphorus in its DNA and other biomolecules, such as proteins.. 25 Comments. ...
We are leading manufacturer and supplier of Herbal products like hair Care Oil, Essential oil, Body Care Products etc. Liparis Herbals Private Limited Kolkata
Brrrrr! Its cold outside. Lots of animals are much better adapted to the cold weather than we are. Polar bears have thick fur, seals and whales have a layer of blubber and some birds migrate.. But what if youre a fish?. Birds and mammals are warm-blooded. They can keep their body temperature higher than the icy environment around them. Fish are cold-blooded. Their body temperature is the same as their surroundings. In the Arctic and Antarctic Oceans, the temperature is very chilly - below 0 degrees Celsius. The salt in the oceans stops them freezing.. Why dont fish freeze?. To stop their blood freezing, some fish that live in the Arctic and Antarctic have special antifreeze proteins.. Antifreeze proteins are very clever. They slow down the formation of bonds between water molecules, which prevents the formation of ice crystals in the fishs blood.. Scientists are working out how they could use these antifreeze proteins as a non-polluting de-icer for cars and machinery. Antifreeze proteins ...
Sea water freezes at -1.9C which presents a problem for any creature that wants to live in Arctic or Antarctic seas. Some species of fish have antifreeze proteins (AFPs) that allow them to live in such environments. Such proteins bind to ice crystals and inhibit their growth. Consequently the freezing point of blood and body…
The report on global Antifreeze market portrays comprehensive information and conducts a complete study to provide latest market updates and information about present and forecast market scenario. The changes taking place in Antifreeze are elaborated in this report to help readers in making vital business decisions. The Antifreeze industry details are provided in the form of graphs, pie-charts to help the emerging and existing market players, buyers, and suppliers in planning the business strategies. These details will fuel the development of their business and will bring huge revenues in return.. Further, this report incorporates both quantitative as well as qualitative data sets which include market framework, executive summary for the global Antifreeze market.The report also includes key players profile description, details on fiscal & accounting, business tactics and fresh developments in global Antifreeze Market.Tools for competition mapping are also inculcated in the report as an assistant ...
heating system antifreeze catologs and heating system antifreeze manufacturers - 4,124 heating system antifreeze Manufacturers, Exporters & suppliers from China
D2982 - 07(2013) Standard Test Methods for Detecting Glycol-Base Antifreeze in Used Lubricating Oils , glycol-base antifreeze, glycol-base coolant, used lubricating oil,
Ingesting a Small Amount of Antifreeze Causes Kidney Failure in Dogs Pound for pound, antifreeze is the heavyweight of poisons seen in small-animal veterin
Title: A-A-52624, Date: 1997-Feb-06, Status: Active, Desc: COMMERCIAL ITEM DESCRIPTION ANTIFREEZE MULTI-ENGINE TYPE (06-FEB-1997) [SUPERSEDING O-A-548 A-A-870 MIL
purchased a 04 mcs alittle under a year ago. have done an oil change, and keep everything looked over pretty good. the coolant tank is alittle low...
Antifreeze proteins (AFPs) enhance the survival of organisms inhabiting cold environments by affecting the formation and/or structure of ice. We report the crystal structure of the first multi-domain AFP that has been characterized. The two ice binding domains are structurally similar. Each consists of an irregular β-helix with a triangular cross-section and a long α-helix that runs parallel on one side of the β-helix. Both domains are stabilized by hydrophobic interactions. A flat plane on the same face of each domains β-helix was identified as the ice binding site. Mutating any of the smaller residues on the ice binding site to bulkier ones decreased the antifreeze activity. The bulky side chain of Leu174 in domain A sterically hinders the binding of water molecules to the protein backbone, partially explaining why antifreeze activity by domain A is inferior to that of domain B. Our data provide a molecular basis for understanding differences in antifreeze activity between the two domains of this
Scientists have discovered that an ice-binding protein (fcIBP) from the sea ice microalga does not fit in the conventional classification of ice-binding proteins, suggesting unknown mechanisms behind its antifreeze property. This finding could lead to a broader application of the antifreeze protein in food and medical industries.
Antifreeze proteins (AFPs) are often called ice-binding proteins and are thought to bind to ice or ice-like crystals exclusively to control their growth. Here molecular recognition repertoire of AFPs has been greatly expanded to other hydroxyl containing, non-ice like compounds. The inhibitory and habit-modifying effects of AFPs on the stable nuclei formation and on the crystals of nucleosides have been first demonstrated.
Get information, facts, and pictures about antifreeze at Encyclopedia.com. Make research projects and school reports about antifreeze easy with credible articles from our FREE, online encyclopedia and dictionary.
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Certain plants and animals protect themselves against temperatures below freezing with antifreeze proteins. How the larva of the beetle Dendroides canadensis manages to withstand temperatures down to -30 degrees Celsius is reported by an international team of researchers led by Prof. Dr. Martina Havenith from the Department of Physical Chemistry II at the Ruhr-Universität in the journal
Antifreeze After watching murder, upon murder shows, one key thing Ive learned about antifreeze is that it has a sweet taste. While Ive never tasted it, I can say that TV has come in quite handy with the knowledge of avoiding antifreeze. The fatal substance is common in driveways in the winter. Some car owners take care of their car very carefully, which can involve antifreeze/coolant changes to prepare for harsh winter weather. A spill is common, and usually unintentional, but the small accident can be a fatal one. The sweet, intoxicating, smell and taste can be a lure for pups. The main ingredient in antifreeze is ethylene glycol. If ingested, the toxic chemical could lead to severe illnesses and even death. According to Petxtreme, "The mortality rate in dogs poisoned by antifreeze ranges from 50 to 70% and is thought to be even higher in cats." That is an extremely high number! If the animal isnt treated immediately, nervous system damage or kidney damage could occur, if death doesnt come ...
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My research involves investigation into synthetic Antifreeze glycoproteins and extremeophile bacteria resistant to cold temperatures within the Gibson group at Warwick chemistry depatment. Further details will be posted at a later date. The image shows a selection of antifreeze proteins (from http://2011.igem.org/Team:KULeuven/Afp) highlighting the large diversity and potential for research ...
A sweet-smelling aroma and antifreeze smell could indicate that the cars heater core is leaking. Other common signs of a bad heater core include a foggy windshield, a water surging sound inside the...
A Sacramento family is mourning the loss of their beloved dog. They believe foul play is involved after their vet discovered antifreeze in the dogs system.
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814-275-2426 Child with a Disability. A child with a disability means a child evaluated in accordance with IDEA §§ 3000.304 through 300.311 as having intellectual disability, a hearing impairment (including deafness), a speech or language impairment, a visual impairment (including blindness), a serious emotional disturbance (referred to in this part as "emotional disturbance"), an orthopedic impairment, autism, traumatic brain injury, an other health impairment, a specific learning disability, deaf- blindness, or multiple disabilities, and who, by reason thereof, needs special education and related services.. For children from 3 years to Kindergarten entrance, the Pennsylvania Department of Education Office of Child Development and Early Learning (OCDEL) operates the preschool early intervention program. OCDEL provides early intervention services through MAWAs (Mutually Agreed Upon Written Arrangements) typically with Intermediate Units or school districts. Legislative and regulatory guidance ...
A diver himself, Cziko worked with other divers to place and maintain a temperature-logging device in McMurdo Sound, Antarctica, one of the coldest marine environments on the planet. The device recorded ocean temperatures there for 11 years, a substantial portion of notothenioids lifespan. Not once in that time did temperatures increase enough to overcome the antifreeze proteins anti-melting effect to completely rid the fishes of their internal ice, the researchers report.. The researchers suspect that the accumulation of ice inside the fishes could have adverse physiological consequences, but none have yet been discovered.. If the fishes are destined to carry ice crystals around all their lives, Cheng said, it is conceivable that ice particles could obstruct small capillaries or trigger undesired inflammatory responses. Cziko likens the potential threat to dangers posed by asbestos in the lungs or blood clots in the brain.. "Since much of the ice accumulates in the fishes spleens, we think ...
1982 by the National Academy of Sciences. Communicated by Norman H. Horowitz, September 28, 1981. We thank Donna Stapleton and Christine Hough-McElhanney for technical assistance and Dr. Geoff Flynn for his advice and his help in performing the automated Edman degradation. We are also grateful to Dr. Joseph Beard and the National Cancer Institute for the gift of reverse transcriptase. This work was supported by grants to P.L.D. and C.-L.H. from the Medical Research Council of Canada and by the award of a Medical Research Council Scholarship to P.L.D. This is contribution 435 from the Marine Sciences Research Laboratory, Memorial University of Newfoundland. The publication costs of this article were defrayed in part by page charge payment. This article must therefore be hereby marked "advertisement" in accordance with 18 U.S.C. §1734 solely to indicate this fact ...
1KDF: Refined solution structure of type III antifreeze protein: hydrophobic groups may be involved in the energetics of the protein-ice interaction.
1KDF: Refined solution structure of type III antifreeze protein: hydrophobic groups may be involved in the energetics of the protein-ice interaction.
Zoarces americanus (4ny6, 1ame, 1b7i, 1b7k, 1ekl, 1gzi, 1hg7, 1jab, 1kde, 1kdf, 1msi, 1msj, 2ame, 2jia, 2msi, 2msj, 2spg, 3ame, 3qf6, 4msi, 5cr7, 5msi, 6ame, 6msi, 7msi, 8ame, 8msi, 9ame, 9msi ...
Pool antifreeze is an insurance policy against freeze damage to pool pipes and plumbing. Non-toxic pool antifreeze is propylene glycol based - protects pool pipes down to -50° F.
Rat and mouse poisons are toxic to children. Antifreeze. Though there are several types of anticoagulants available as rat poison, some populations. The liver metabolizes ethylene glycol into glycolate and oxalate, which cause extensive cellular damage in various tissues, especially the kidneys, but across many different organs. A greedy rat can eat enough poison to kill 20 rats before he starts to feel sick and if a dog or cat eats the rat, the poison is transferred. Most rodent poisons use anti-coagulants that kill the animals by causing uncontrollable bleeding. But usually not quickly. It may sample a small dose but then it would realise that it is not good & not take anymore. There are some types of road salt that apparently contain some antifreeze which can be toxic to dogs. Varmints learn fast by habit and ease of procuring the prey. She said shes received four birds in the past week that have died from poisoning. In the photo below, a homeowner attempted to perform do it yourself raccoon ...
Antifreeze is highly toxic to cats. Please read our blog on antifreeze poisoning and keeping your cat (and others) safe as the weather gets colder.
Sea snail` (?). Zoology|Zool. (a) A small fish of the genus Liparis, having a ventral sucker. It lives among stones and seaweeds. (b) Any small cr...
SPRINGFIELD, Mo. (AP) - A southwest Missouri woman is charged with using antifreeze to fatally poison her husband and son and attempt to kil…
Although painted turtles dont have much else in common with automobiles, their wintertime coping strategies include antifreeze, too.
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Basically, heres how it goes(year by year): Well first we cant be sure that the winter flounder stocks are disappearing... Next, well there may be less winter flounder but lets wait and see if their is a recovery... Then, they havent returned to prior levels yet, perhaps somehting is wrong... Next, lets investigate possible reasons for their decline, but do nothing to help the population to recover... Further, well the investigations have yielded inconclusive results so more studies need to be undertaken before anything is put in stone... Finally, we dont know why the flounder are going away, however, we do not feel the best course of action is trying to repopulate, but actually to correct the problems of which we have no idea.... NICE GOING GOVERNMENT IDIOTS ...