A metabolite of beta-asarone is the reason Acurus calamus is known in some cultures as a psychedelic. However, not all Acorus calamus contains sufficient quantities of beta-asarone to be effective. Acorus calamus from Nepal typically contains a large amount of beta-asarone. Acorus calamus from India usually contains very little beta-asarone, and will cause extreme nausea before doses high enough to get some minor effects from beta-asarone are ingested.. Its important to note that beta-asarone itself is not active. One of its metabolites can produce psychedelic effects in man. Not everyones body metabolizes beta-asarone the same way, leading to different results for different individuals. Some people are not able to experience psychedelic effects from ingesting beta-asarone. This is because their bodies do not produce enough of the active metabolite to experience effects.. The active metabolite of beta-asarone is currently unidentified. There has been speculation of it being an amphetamine, ...

Therapeutic properties:. Below are a few therapeutic properties that research studies have shown regarding Trans-anethole ((E)-anethole). Please keep in mind these are for the specific chemical component and may not be representative of the entire essential oil it is found in depending on the percentages shown in gas chromatography and mass spectronomy analysis.. Analgesic: (E)-Anethole is moderately analgesic, in both in vitro and in vivo tests2. Antifungal: anethole has been shown to exhibit synergistic antifungal activity against a budding yeast3 and candida6. Anti-inflammatory: (E)-Anethole blocks cellular responses induced by Tumor Necrosis Factor indicating an anti-inflammatory action4 (TNF is a chemical messenger that induces cell death. TNF is directed at abnormal cells to assist in preventing the formation of tumors.). There was a study also that showed anethole to be a potential candidate in supporting the restoration of functional dyspepsia.5. Balanced use:. It is important to ...

We have shown previously that low doses of selective sigma (sigma)- receptor ligands potentiate the excitatory response of pyramidal neurons to NMDA in the CA3 region of the dorsal hippocampus in the rat. Because progesterone competitively displaces the binding of the ligand N-[3H]allyl-normetazocine (SKF-10,047), the present studies were undertaken to determine in vivo the effect of neuroactive steroids on NMDA-induced excitation of rat CA3 pyramidal neurons. Low doses of dehydroepiandrosterone (DHEA) potentiated the NMDA response selectively and dose-dependently. The effect of DHEA was reversed by the selective sigma antagonist N-dipropyl-2-(4-methoxy-3- (2-phenylethoxy)phenyl)- ethylamine monohydrochloride (NE-100) and by haloperidol, but not by spiperone. Progesterone had no effect by itself but reversed, at low doses, the potentiation of the NMDA response induced by DHEA as well as those induced by nonsteroidal sigma ligands. Neither pregnenolone nor pregnenolone sulfate had any effect on ...

Looking for online definition of o-anisidine in the Medical Dictionary? o-anisidine explanation free. What is o-anisidine? Meaning of o-anisidine medical term. What does o-anisidine mean?

Valecobulin (CKD516) is a valine prodrug of (S516) and a vascular disrupting agent (VDA). Valecobulin is a potent β-tubulin polymerization inhibitor with marked antitumor activity against murine and human solid tumors.

Discover the incredible weight loss benefits of anise, how to best prepare it and how much you should use to get maximum benefit from anise - one of natures amazing fat burning foods. Anise, alternately referred to as aniseed and sweet cumin, is categorized as both a vegetable and an herb; it is part of the same family where you would find fennel, dill, caraway, and cumin. The leaves, seeds, and flowers of anise can be put into foods as well as different medications. The anise plant is tall and has small, feathery green leaves. The plant has white flowers and its fruit, which is frequently referred to as a seed, has the appearance of a ribbed seed. Ripened anise seeds are greenish brown or gray-green in color. Anise tastes somewhat like fennel with a hint of licorice flavor. DieselHemp.com offers the best CBD joints. Fat Fighting Benefits of Anise. The medicinal qualities of anise have been known to man as far back as the ancient Egyptians and Romans. Anise aids in the bodys digestion and fat ...

1-Methoxy-4-(2-propenyl)benzene, also known as methylchavicol or estragol, belongs to the class of organic compounds known as anisoles. These are organic compounds containing a methoxybenzene or a derivative thereof. 1-Methoxy-4-(2-propenyl)benzene is an extremely weak basic (essentially neutral) compound (based on its pKa). 1-Methoxy-4-(2-propenyl)benzene is a sweet, alcohol, and anise tasting compound. Outside of the human body, 1-Methoxy-4-(2-propenyl)benzene is found, on average, in the highest concentration within a few different foods, such as anises, fennels, and sweet basils and in a lower concentration in cumins, tarragons, and parsley. 1-Methoxy-4-(2-propenyl)benzene has also been detected, but not quantified in, several different foods, such as citrus, chinese cinnamons, caraway, fats and oils, and cloves. This could make 1-methoxy-4-(2-propenyl)benzene a potential biomarker for the consumption of these foods. 1-Methoxy-4-(2-propenyl)benzene, with regard to humans, has been linked to ...

This study investigates the mechanisms of gas phase anisole and phenol conversion over zeolite catalyst. These monomers contain methoxy and hydroxyl groups, the predominant functionalities of the phenolic products of lignin pyrolysis. The proposed reaction mechanisms for anisole and phenol are distinct, with

Ischemic hypoxic brain injury often causes irreversible brain damage. The lack of effective and widely applicable pharmacological treatments for ischemic stroke patients may explain a growing interest in traditional medicines. β-Asarone, which has significant pharmacological effects on the central nervous system (CNS), was used in the prevention of cerebral ischemia in this paper. The right middle cerebral artery occlusion model was used in the study. The effects of β-Asarone on mortality rate, neurobehavior, grip strength, lactate dehydrogenase, glutathione content, Lipid peroxidation, glutathione peroxidase activity, glutathione reductase activity, catalase activity, Na+-K+-ATPase activity and glutathione S transferase activity in a rat model were studied respectively. β-Asarone significantly improved the neurological outcome after cerebral ischemia and reperfusion in terms of neurobehavioral function in rats. Meanwhile, supplementation of β-Asarone significantly boosted the defense mechanism

TY - JOUR. T1 - Rapid conversion of glycerol to lactic acid under alkaline hydrothermal conditions, by using a continuous flow reaction system. AU - Shimanouchi, Toshinori. AU - Ueno, Shouhei. AU - Shidahara, Kazuki. AU - Kimura, Yukitaka. PY - 2014. Y1 - 2014. N2 - A rapid conversion of glycerol to lactic acid (lactate) could be successfully achieved under alkaline hydrothermal conditions, by using a continuous flow reaction system. A rapid conversion by a continuous flow-type reaction system made it possible to achieve the reaction under high-temperature conditions without side reactions. The rapid conversion and high reaction yield (reaction: 2min; yield: 90%) resulted from the rapid temperature-shift advantageous for the inhibition of side reactions.. AB - A rapid conversion of glycerol to lactic acid (lactate) could be successfully achieved under alkaline hydrothermal conditions, by using a continuous flow reaction system. A rapid conversion by a continuous flow-type reaction system made it ...

1-tert-butyl-4-propan-2-yl-5-(trifluoromethyl)imidazole chemical properties, What are the chemical properties of 1-tert-butyl-4-propan-2-yl-5-(trifluoromethyl)imidazole 129247-52-5, What are the physical properties of 1-tert-butyl-4-propan-2-yl-5-(trifluoromethyl)imidazole ect.

2-(2-hydroxyethoxy)ethan-1-ol 2-[2-(2-hydroxyethoxy)ethoxy]ethan-1-ol 2-methoxyethan-1-ol 3,6,9,12,15,18,21-heptaoxatricosane-1,23-diol 3,6,9,12,15-pentaoxaheptadecane-1,17-diol 3,6,9,12-tetraoxatetradecane-1,14-diol bis(ethane-1,2-diol) 14-({3-[3-(2H-1,2,3-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl]propanoyl}oxy)-3,6,9,12-tetraoxatetradecan-1-yl 3-[3-(2H-1,2,3-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl]propanoate 14-hydroxy-3,6,9,12-tetraoxatetradecan-1-yl 3-[3-(2H-1,2,3-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl]propanoate tris(17-({3-[3-(2H-1,2,3-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl]propanoyl}oxy)-3,6,9,12,15-pentaoxaheptadecan-1-yl 3-[3-(2H-1,2,3-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl]propanoate) tris(17-hydroxy-3,6,9,12,15-pentaoxaheptadecan-1-yl 3-[3-(2H-1,2,3-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl]propanoate) 2-({3-[3-(2H-1,2,3-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl]propanoyl}oxy)ethyl ...

Patients randomized to vernakalant received a 10-minute infusion of 3 mg/kg vernakalant in one infusion line, followed by a 15-minute observation period and an additional 10-minute infusion of 2 mg/kg vernakalant if still in AF. To maintain blinding, a 60-minute infusion of placebo (5% dextrose in water) was administered in a second infusion line, followed by a maintenance infusion of placebo for an additional 60 minutes. Patients randomized to amiodarone received a 60-minute infusion of 5 mg/kg amiodarone in one infusion line, followed by a maintenance infusion of 50 mg amiodarone over an additional 60 minutes (equivalent to approximately 15 mg/kg over 24 hours). To maintain blinding, these patients received a 10-minute infusion of placebo (normal saline) in a second infusion line, followed by a 15-minute observation period and a second 10-minute infusion of placebo if still in AF ...

The report generally describes 2-tert-butyl-4-(α-carbethoxytridecyloxy)-phenol, examines its uses, production methods, patents. 2-tert-Butyl-4-(α-carbethoxytridecyloxy)-phenol

Read about the chemical and physical properties of 8-tert-Butyl-5,6-dimethyl-8H-pyrrolo[3,2-e][1,2,4]triazolo[1,5-a]pyrimidine. Get 8-tert-Butyl-5,6-dimethyl-8H-pyrrolo[3,2-e][1,2,4]triazolo[1,5-a]pyrimidine molecular formula, CAS number, boiling point, melting point, applications, synonyms and more here.

Most of the ADCs currently in the market and in clinical development carry tubulin polymerization inhibitors such as T-DM1 and SGN-35 (Brentuximab vedotin; ref. 13). We synthesized a novel ADC with a topoisomerase I inhibitor, which has a different mechanism of action from tubulin polymerization inhibitors, and a novel self-immolative linker system using an aminomethylene (AM) moiety. Although other cleavable linker systems applied to SGN-35 (Brentuximab vedotin) and several ADCs release amino group-containing payloads, this AM self-immolative linker system is able to release DXd containing the hydroxyl group from DS-8201a. Moreover, this novel linker-payload system enables a reduction in the hydrophobicity of the ADC and helps increase its DAR. In the case of T-DM1, lysine conjugation and noncleavable systems are used, and it is quite a different system from DS-8201a. DS-8201a showed potent HER2-specific efficacy both in vitro and in vivo, and by drug conjugation maintained the functional ...

TY - JOUR. T1 - Vernakalant. T2 - Pharmacology, electrophysiology, safety and efficacy. AU - Naccarelli, Gerald V.. AU - Wolbrette, Deborah L.. AU - Samii, Soraya. AU - Banchs, Javier E.. AU - Penny-Peterson, Erica. AU - Stevenson, Robert. AU - Gonzalez, Mario D.. PY - 2008/5/1. Y1 - 2008/5/1. N2 - The development of new antiarrhythmic agents for the treatment of atrial fibrillation is advancing simultaneously on several fronts. The molecular structure of existing agents such as amiodarone is being modified in an attempt to improve safety and reduce adverse effects. Similarly, atrial-selective antiarrhythmic drugs are being developed to minimize the occurrence of ventricular proarrhythmia. One of these atrial-selective compounds is vernakalant, which has demonstrated efficacy in terminating atrial fibrillation when given intravenously. In addition, preliminary data suggest that it could also suppress recurrences when used orally. This paper reviews the pharmacology, electrophysiology, efficacy ...

The authors of the AVRO study also assert that, while both treatments were found to be safe and well tolerated, vernakalant had low proarrhythmic potential and provides a rapidly acting therapeutic alternative.. The research team, led by Professor John Camm from St. Georges University of London, conducted a randomized, double-blind, multicenter superiority trial in 254 adult patients with underlying cardiovascular disease, making certain antiarrhythmic drugs inappropriate for use. 116 patients in each group received at least one dose of the study drug. Approximately 30% of patients in both treatment arms had no AF episodes prior to the initial diagnosis, whereas one-third had at least three.. Those in the vernakalant study arm received a 10-minute infusion of 3 mg/kg followed by an additional 10-minute infusion of 2 mg/kg if needed after a 15-minute observation period. Amiodarone patients received a 60-minute infusion of 5 mg/kg followed by an additional 60-minute maintenance infusion of 50 ...

The process of producing styrene comprising the use of a solution of paranitrosophenol in n-methyl pyrollidone as a polymerization inhibitor during said process. A polymerization inhibitor system for monomers comprising a solution of a polymerization inhibitor in a solvent which is miscible with the feedstock for the monomer and the monomer. Dinitro-orthocresol works very well, but is extremely toxic. NAUGARD® SFR inhibitor by SI Group is a sterically hindered nitroxyl stable free radical. According to the report findings, the certificate of inhibitor, issued by the cargo surveyor at the time of loading, stated that the TBC should remain effective for between 60 and 90 days. It can be used when storing highly reactive monomers. TISP is based on the new principles of Inhibition. Specialty Chemicals HP. AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO ...

The first indication in determining the quality of wine is if there is presence of any faults. The more common ones include cork taint (TCA) and oxidation and can be detected when an aroma or flavor in the wine appears off or just wrong. Cork taint occurs when 2,4,6 - Tricloranisole or TCA, generated by naturally-occurring fungi that often exist in the crevices of wood or cork, comes into contact with chlorine compounds present in pesticides, cleaning agents, wood treatments, etc. When cork taint occurs, the wine will have a musty, moldy aroma. Controlling the source of TCA has proven extremely difficult and currently there are no solutions.. Another wine fault is the oxidation or reduction of the wine - which happens when wines are either exposed to too much or too little oxygen respectively. When oxidation occurs, this usually results in a breakdown of its attractive color. Whites go a dull brown/straw, rosés go brown/orange, reds become paler with an orange/brown rim. Chilling grapes and ...

The present study reports densities (ρ), viscosities (η) and ultrasonic speeds (U) of pure dioxane (DOX), anisole (ANS), toluene (TOL) and ethylbenzene (ETB) and their binary liquid mixtures over the entire composition range at 293, 298, 303, 308 and 313 K. From the experimental data excess molar volume (VmE), excess intermolecular free length (LfE), excess adiabatic compressibility (βE) and excess acoustic impedance (ZE) have been computed. The excess values were correlated using Redlitch-Kister polynomial equation to obtain their coefficients and standard deviations (σ). With increase in temperature, the binary mixture of DOX+ANS shows larger deviations in βE, LfE and smaller deviations in ZE, VmE. These results suggest that ANS has strong molecular interactions with DOX than ETB and TOL.

United States Patent C 3,766,288 PROCESS FOR PREPARATION OF ALKENYLBENZENE Takeo Shima, Takanori Urasaki, and Iwao Omae, Iwakuni, Japan, assignors to Teiiin Limited, Osaka, Ja an N3 Drawing. Filed Mar. 27, 1972, Ser. No. 238,584 Claims priority, application Japan, Mar. 29, 1971, 46/ 18,602 Int. Cl. C07c 3/52 U.S. Cl. 260-668 B 9 Claims ABSTRACT OF THE DISCLOSURE A process for preparing alkenylbenzenes, which comprises reacting alkylbenzenes with 1,3-butadiene at an elevated temperature in the presence of an alkali metal catalyst in the substantial absence of oxygen and mois ture, wherein such catalyst is composed of (1) 0.005 to 0.4% by weight, based on the alkylbenzene, of metallic potassium, and (2) metallic sodium in an amount expressed by the following equation (4.1x+2.0) ;Na;(0.073x+0.05) wherein x represents the amount in weight percent of the metallic potassium. This invention relates to an improved process for preparing alkenylbenzenes by reacting alkylbenzenes with 1,3- butadiene in the ...

Looking for anise? Find out information about anise. annual plant of the family Umbelliferae , native to the Mediterranean region but long cultivated elsewhere for its aromatic and medicinal qualities. Explanation of anise

Shop for organic, ground, or whole anise online. Free delivery from € 47,90. Sonnentor Organic Star Anise, Sonnentor Organic Anise, Cosmoveda Organic Star Anise, ground. Free Hotline: 0800 55 66 40 506.

Many would argue that the sense of smell is our far most important sense when it comes to evaluating wine. This is because the olfactory sense plays a fundamental role both in the perception of aroma and also flavour. Without it all wines,3 rather than just a few, would appear to be uninteresting alcoholic solutions of acid and sugar. The sense of smell is by far the most powerful of our senses. It can discriminate between tens of thousands of different aromas, and is capable of detecting some compounds found in wine at levels around a single part per trillion. An example of this is the compound 2,4,6 Trichloroanisole, the primary compound responsible for cork taint. Some people can detect it at around 1 part per trillion which is analogous to a single second in thirty two years. Not bad I suppose, but when you think that an Alsatian or Beagle probably sees a three dimensional colliedescope like scent world, our olfactory efforts seem pretty pathetic in comparison. The olfactory system ...

Hydroquinone cream can be found in Germany through the store called the Chemical point. Some of them include 2-(1-Phenylethyl) hydroquinone. Hydroquinone, pharma grade, Hydroquinone dimethyl ether (1, 4-Dimethoxybenzene) and many more. There are many online pharmacies and online stores that provide all kinds of medicines including Hydroquinone.. One tube will cost $12.99 and $35.99 for three tubes. Shopeastwest is another medicine center or online pharmacy that will provide you with all kinds of generic and cheap drugs. There are other stores like Melalong by Ajanta Pharma users who are worried and confused about without worrying about its quality or how to buy without becoming confused in complicated websites. Shopeastwest provides you with a quality or how to buy with being confused in complicated websites.. All the drugs from Shopeastwest are delivered by FDA certified pharmaceutical companies and are tested for quality. The user friendly nature of the website can provide you with the best ...

Email: [email protected] Web: http://www.an-gene.com/ Name CAS ID ETHYL PICOLINATE 2524-52-9 AG-E-76780 1-BROMO-2,5-DIMETHOXYBENZENE 25245-34-5 AG-E-76783 4-(4-MORPHOLINO)ANILINE 2524-67-6 AG-E-76788 BENZENE, ETHENYL-, DIMER 25247-68-1 AG-E-76794 POLYVINYLPYRROLIDONE CROSS-LINKED 25249-54-1 AG-E-76807 2-BROMO-5-IODOBENZOIC ACID 25252-00-0 AG-E-76822 DIPROPYLENE GLYCOL 25265-71-8 AG-E-76901 METHYL ALPHA ?BROMO-2-CHLORO-PHENYL ACETATE 25270-30-4 AG-E-76948 1-METHYL-PIPERIDINE-2-CARBOXYLIC ACID X HCL 25271-35-6 AG-E-76951 3-CHLOROMETHYL-1,2,4-TRIAZOLIN-5-ONE 252742-72-6 AG-E-76966 DIBUTYL PHENYL PHOSPHATE 2528-36-1 AG-E-77008 8-BROMO-5-NITRO-ISOQUINOLINE…

4-Tert-butyl-2-[(dimethylamino)methyl]-6-(prop-2-en-1-yl)phenol | C16H25NO | CID 223627 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

2-tert-butyl-6-(2-phenylpropan-2-yl)phenol | C19H24O | CID 577322 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

Learn more about tert-butyl-4-5-bromo-1h-indol-3-yl-3-6-dihydro-1-2h-pyridinecarboxylate. We enable science by offering product choice, services, process excellence and our people make it happen.

Ampyridine offer gram to tons of CAS No.1428537-19-2, 2-[(4R)-4-tert-Butyl-4,5-dihydro-2-oxazolyl]-5-(trifluoromethyl)pyridine,AM11903,purity 98% Min.,MSDS.

Learn more about tert-butyl-4-hydroxy-3-trifluoromethyl-piperidine-1-carboxylate. We enable science by offering product choice, services, process excellence and our people make it happen.

Pesticide properties for N-((8-tert-butyl-1,4-dioxaspiro(4.5)dec-2-yl)methyl)propan-1-amine, including approvals, environmental fate, eco-toxicity and human health issues

4-tert-butyl-3-methyl-phenol - Buyers Guide for Chemicals is a directory of chemicals, chemical suppliers and producers. More than 140,000 products, 270,000 supply sources and 4,400 company addresses. Search for free and find new suppliers for chemical products, pharmaceuticals and APIs.

2-tert-Butyl-7-fluoro-5-nitro-1H-indole/ACM952664947 can be provided in Alfa Chemistry. We are dedicated to provide our customers the best products and services.

Buy 5-tert-Butyl-2-[2-(4-fluoro-phenoxy)-ethyl]-2,4-dihydro-pyrazol-3-one (CAS 864685-46-1), a product for proteomics research, from Santa Cruz.

2-(1-tert-butyl-1H-pyrazol-4-yl)acetic acid; CAS Number: 1784925-12-7; find Enamine-ENAH03A0E8B0 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich

2-tert-Butyl-1H-imidazole. CAS Number: 36947-69-0. Catalog Number: AA003HUZ. MDL Number: MFCD16618480. Molecular Formula: C7H12N2. Molecular Weight: 124.1836. AA Blocks.

chemBlink provides information about CAS # 152828-25-6, 2-(4-Aminophenyl)-6-tert-butyl-1H-pyrazolo[1,5-b][1,2,4]triazole, molecular formula: C12H11N5.

The test item consisted of non-transparent particles which had a very strong tendency for agglomeration. The particles had a sticky behaviour and were electrostatically charged after sieving. A large part of the test item was present in form of agglomerates with a diameter above 1 mm. The aforementioned effects opposed a measurement via sieve analysis and influenced the results of the study using laser diffraction. Hence, the test item was sieved with a mesh size of 1000 µm. Only 43% (w/w) of the test item passed the sieve and only this fraction was measured with laser diffraction. Median particle size D (v, 0.5): 50% of particle volume or particle mass with lower particle diameter 1st test series: 11.8 µm 2nd test series: 13.9 µm Average of median particle size: 12.8 µm Particle size D (v, 0.1): 10% of particle volume or particle mass with lower particle diameter 1st test series: 3.8 µm 2nd test series: 4.2 µm Average of the particle size: 4.0 µm Particle size D (v, 0.9): 90% of particle ...

Butylated hydroxyanisole was tested for carcinogenicity in two experiments in rats and in two experiments in hamsters by administration in the diet, inducing benign and malignant tumours of the forestomach.. Butylated hydroxyanisole was studied in mice and rats for its ability to modify the carcinogenicity of selected chemical agents. When administered with known carcinogens, butylated hydroxyanisole either enhanced, inhibited or had no effect on carcinogenicity.. Butylated hydroxyanisole administered to rats at maternally toxic and occasionally lethal doses during, or before, during and after, gestation induced slight embryotoxicity but no definite indication of teratogenicity. No effect was seen in rabbits, pigs or rhesus monkeys.. In rats, feeding of butylated hydroxyanisole in the diet caused superficial necrosis, ulceration and hyperplasia of the squamous epithelium of the forestomach. Induction of forestomach hyperplasia also occurs in hamsters. Administration of butylated hydroxyanisole ...

A novel series of tubulin polymerization inhibitors, based on fluorinated derivatives of isocombretastatin A-4 was synthesized with the goal of evaluating the effect of these compounds on the proliferative activity. The introduction of fluorine atom was performed on the phenyl ring or at the linker between the two aromatic rings. The modification of isoCA-4 by introduction of difluoromethoxy group at the para-position (3i) and substitution of the two protons of the linker by two fluorine atoms (3m), produced the most active compounds in the series, with IC50 values of 0.15-2.2 nM (3i) and 0.1-2 nM (3m) respectively, against a panel of six cancer cell lines. Compounds 3i and 3m had greater antiproliferative activity in comparison with references CA-4 or isoCA-4, the presence of fluorine group leads to a significant enhancement of the antiproliferative activity. Molecular docking studies indicated that compounds 3i and 3m occupy the colchicine binding site of tubulin. Evaluation of cytotoxicity in ...

Looking for online definition of 2-Tert-Butyl-4-Methylphenol or what 2-Tert-Butyl-4-Methylphenol stands for? 2-Tert-Butyl-4-Methylphenol is listed in the Worlds largest and most authoritative dictionary database of abbreviations and acronyms

The general belief that chemical structure determines the biological effect of drugs has led to several techniques to establish structure-activity relationships (SAR) that is useful in the development of more active compounds. Predicting toxic effects based on SAR, one can obtain toxicological data with a low cost-benefit ratio. Chlorophenols that represent a class of toxic agents frequently used in industrial processes are not satisfactorily described in the literature in relation to their toxicity. The main objective of this work is to relate the microbial activities of phenol, anisole and their chlorinated derivatives on Chromobacterium violaceum respiration with their physicochemical properties. Anisole and its chlorinated derivatives were used to evaluate the influence of phenol acidity on biological activity. The calculations were carried out at the semi-empirical AM1 and ab initio DFT levels employing the basis sets CEP-31G, CEP-31+Ge CEP-31G** that were parameterized using the ...

You can now access full text articles from research journals published by CSIR-NISCAIR! Full text facility is provided for all nineteen research journals viz. ALIS, AIR, BVAAP, IJBB, IJBT, IJCA, IJCB, IJCT, IJEB, IJEMS, IJFTR, IJMS, IJNPR, IJPAP, IJRSP, IJTK, JIPR, JSIR & JST. NOPR also hosts three Popular Science Magazines viz. Science Reporter (SR), Vigyan Pragati (VP) & Science Ki Duniya (SKD) and a Natural Products Repository (NPARR ...

Triveni Chemicals, Vapi - Manufacturers and exporters of 2-quinoline carboxaldehyde, 2, 5-dimethoxyacetophenone, p-anisic acid, 4-methoxybenzoic acid, 3, 5-dinitrosalicylic acid, 1, 4-dimethoxybenzene, dimethoxy benzene, dimethoxybenzene pharmaceutical, dinitrosalicylic acid chemical, anisic acid, anisic acid compound, 4-methoxybenzoic acid compound, bis(trimethyl) trifluoroacetamide, ethanamidic acid, pyridinium-p-toluene sulfonate

5-[5-tert-butyl-2-[(3-methylphenyl)methyl]pyrazol-3-yl]-3H-1,3,4-oxadiazole-2-thione chemical properties, What are the chemical properties of 5-[5-tert-butyl-2-[(3-methylphenyl)methyl]pyrazol-3-yl]-3H-1,3,4-oxadiazole-2-thione 306937-16-6, What are the physical properties of 5-[5-tert-butyl-2-[(3-methylphenyl)methyl]pyrazol-3-yl]-3H-1,3,4-oxadiazole-2-thione ect.

Also known as aniseed, anise (Pimpinella anisum) is an annual herb perhaps best known for its signature licorice-like flavor and spicy-sweet scent. It can reach a height of 2 feet, is covered in soft hairs, and bears white flowers and oblong schizocarp fruits. Aniseed should not be confused with star anise (Illicium verum), which is an entirely different plant that merely shares a similar flavor and scent profile. Aniseed is cultivated in southern Europe, Turkey, central Asia, India, China, and Japan, as well as Central and South America.. Anise seeds naturally contain flavonoids and fatty oils, as well as its main component anethole. These seeds have been used in cuisines around the world for their licorice-like flavor, and are popularly distilled to extract their spicy-sweet smelling essential oil. Anise seeds have also been used in ancient Egypt to make tea, by ancient Roman naturalist Pliny the Elder, and in traditional European wellness practices for an array of applications, such as in ...

Are you looking for some tips on fennel & other essential oils with (E)-anethole? From safety concerns, therapeutic actions, and applications you can find it...

Butylated Hydroxyanisole/Butylated Hydroxytoluene is a chemical preservative that is added to oils that are used in dog foods and treats. BHA is a combination of isomers 3-tert-butyl-4-hydroxyanisole and 2-tert-butyl-4-hydroxyanisole and BHT is a mixture of 3,5-di-tert-butyl-4-hydroxytoluene; methyl-di-tert-butylphenol; and 2,6-di-tert-butyl-para-cresol.. The ingredient is derived from natural preservatives that are found in all dry dog food. Its added to commercial products to extend the shelf life of the product by up to a year, and is one of the more inexpensive preservatives available. The FDA states that it can be used safely to preserve the fats and oils that are added to the pet food and to prevent them from spoiling or becoming oxidized. Its also easy for dogs to digest, but is known as a possible carcinogen by the State of California. BHA/BHT is commonly used in cosmetics, petroleum, embalming fluids and pesticides. Although its deemed to be safe to use, studies have shown that the ...

The accelerating effect of mature males of the desert locust,Schistocerca gregaria, on the maturation of immature male and female conspecifics was confirmed. The onset of sexual activity was found to correlate with yellowing of the male insects. Using the colour as an indicator of maturation, the maturation-hastening effect of an hexane extract from mature males was also confirmed. Likewise, volatiles from mature males placed in the upper storey of a two-chamber bioassay system (no visual or tactile contact possible) and charcoal-trapped volatiles from the mature males also induced accelerated maturation in recipient males placed in the lower storey. GC and GC-MS analysis of volatiles collected from 4-week-old mature males showed the presence of anisole, benzaldehyde, veratrole, phenylacetonitrile and 4-vinylveratrole, roughly at the ratio 4.8:7.0:3.3:79.8:5.0. In addition, guaiacol, phenol, benzoylnitrile, benzyl alcohol and 2-benzoyloxyphenylacetonitrile were present in smaller amounts. These ...

Seed coat crude extracts of white-coloured ITA-256, white and brown-coloured TVS-716, deep brown-coloured IT-90K and light brown-coloured Ife brown cowpea varieties were analyzed for the presence and amount of total phenol, tannin and flavonoid content. Crude extracts of the cowpea varieties were analyzed for antioxidant activity using the Thiobarbituric Acid (TBA) assay. The seed coat extracts were added sepa-rately to 200 g of minced broiler meat sample at the rate of 0.05% of the weight of the meat and their effect compared to that of the synthetic antioxidant, butylated hydroxyl anisole (BHA) added to the meat at the rate of 0.05%. Each sample was divided into 16 parts of 12.5 g each. Eight of these were cooked while the other 8 parts were left raw. Antioxidant effect of the seed coat extracts was determined during refrigerated storage of raw and cooked minced broiler meat. All the cowpea varieties studied except TVS-716 contained phenol, tannin and flavonoids. TVS-716 contained only phenol and

Electronic Supplementary Material (ESI) for ChemComm. This journal is © The Royal Society of Chemistry 2014 Highly ordered honeycomb pattern of surfactant-free bio-compatible film via improved phase separation method Van-Tien Bui,a Seung Hyeon Kob and Ho-Suk Choi*a a Department of Chemical Engineering, Chungnam National University, 220 Gung-Dong, YuseongGu, Daejoen 305-764, Korea. b Center for Nanoscale Science and Technology, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA. Experimental Section The PLA was received from NatureWorks (USA) and dried in a vacuum oven at 40°C before use. Copper foil (99.8% pure; thickness 25 µm) was obtained from Sigma-Aldrich. Copper substrates were washed with dilute acetic acid and distilled water followed by blow-drying in nitrogen gas prior to use. Chloroform (anhydrous, with amylenes as stabilizer, ≥99%), methanol (anhydrous, 99.8%), and anisole (anhydrous, 99.7%) were purchased from Sigma-Aldrich and used as received. The ...

CAS 2409-55-4 p-Cresol, 2-tert-butyl- * 2-t-Butyl-p-cresol * o-tert-Butyl-p-cresol * 2-terc.Butyl-p-kresol * 2-t-Butyl-4-methylphenol * 2-(1,1-Dimethylethyl)-4-methylphenol * 4-Methyl-2-t-butylphenol * 4-Methyl-6-t-butylphenol * Phenol, 2-(1,1-dimethylethyl)-4-methyl- msds toxicity property

If Spanish architect Antoni Gaudí had designed a transition-metal complex, it would have looked like [tris(pyrazolyl)borate]W(NO)[P(CH3)3](η2-benzene). As gaudy as this molecule appears, chemists have found it to be a versatile synthetic tool for binding aromatic molecules such as phenols, pyridines, pyrroles, and naphthalenes and dearomatizing them, a key step in building the core structures of natural products and other bioactive compounds. One drawback to the tungsten reagent is that its prepared as a racemic mixture, so the products obtained using it are racemic mixtures that must be separated before continuing. A research team led by W. Dean Harman of the University of Virginia has solved that problem by devising a method to isolate the (R) and (S) versions of the tungsten complex so they can be used in enantioselective dearomatizations (J. Am. Chem. Soc. 2015, DOI: 10.1021/jacs.5b00490). The researchers first protonated the dimethoxybenzene analog of the tungsten complex with L- or ...

Butylated hydroxyanisole (BHA) is a commonly used food additive with demonstrated inhibitory action against chemical carcinogenesis in animals. In order to elucidate the mechanism of the anticarcinogenic action, the effects of BHA on benzo(a)pyrene (BP) metabolism were studied with lung microsomes from female mice. BHA treatment (0.5% in the diet for 7 days) inhibited BP metabolism and altered the ratios among different metabolites as analyzed by high-performance liquid chromatography. The treatment reduced the metabolic formation of 9,10-dihydroxy-9,10-dihydrobenzo(a)pyrene, but not the production of 3-hydroxybenzo(a)pyrene and trans-4,5-dihydroxy-4,5-dihydrobenzo(a)pyrene. Since the gross microsomal cytochrome P-450 content was not significantly affected by the treatment, the change of regioselectivity in BP metabolism was probably due to the alteration of cytochrome P-450 isozyme composition by dietary BHA. General and regioselective inhibition of BP metabolism was also observed when BHA was ...

The antifungal properties of Illicium verum essential oil (IV-EO) against a toxigenic strain of Aspergillus flavus (A. flavus) were analyzed in order to determine its use in the preservation of lotus seeds. GC/MS analysis of IV-EO revealed that its main components are trans-anethole (91.32%), D-Limonene (2.0%) and estragole (2.0%). The antifungal activity of IV-EO against A. flavus infection was a ...

FENNEL. The same oils found in anise are found in fennel, giving both the tell-tale odor and taste of licorice. One of these oils, anethole, is believed to have anti-fungal and anti-bacterial properties. Known primarily for its use in Italian dishes, the fennel bulb contains the B vitamin complex but boasts a high amount of folate in particular. Fennel also contains vitamin C, calcium, copper, iron, magnesium, manganese, potassium, selenium and zinc.. The fennel bulb, which resembles a fattened celery bunch base, can be sliced thin and eaten raw in salads. In its raw form, it has a fresh, cool, mild flavor. To impart more of an anise flavor, cook the fennel. Any cooking method that induces caramelization, such as braising, roasting or grilling, will add a sweet element close to candied licorice. The entire plant is edible. So dont toss the dill-like leaves which can be utilized like an herb in any dish.. ...

Abstract: The aim of this study was to evaluate the viability of near infrared spectroscopy (NIRS) to detect the anomaly known as yellow stain on cork granulate. Detecting this anomaly is crucial to the cork granulate stopper industry, since it is associated with the presence of 2.4.6-Trichloroanisole (TCA), this compound having been identified as the main agent responsible for cork off-flavours. Samples for the NIRS spectra were prepared by mixing in different proportions cork granulate with high visual quality and cork granulate with yellow stain, obtaining 120 samples with 8 different percentages of yellow stain (0, 5, 10, 15, 25, 35, 50 and 100%). Two spectra per sample were collected using a Bruker MPA spectrophotometer and the partial least squares (PLS) method was used to obtain numerous equations. The best equation was obtained by utilizing the standard normal variate (SNV) spectral preprocessing, making use of only one specific part of the near infrared spectral range: 9400-4250 cm-1. This

Sigma receptor (σR) antagonists attenuate many behavioral effects of cocaine but typically not its reinforcing effects in self-administration procedures. However, the σR antagonist rimcazole and its N-propylphenyl analogs, [3-(cis-3,5-dimethyl-4-[3-phenylpropyl]-1-piperazinyl)-propyl]diphenylamine hydrochloride (SH 3-24) and 9-[3-(cis-3,5-dimethyl-4-[3-phenylpropyl]-1-piperazinyl)-propyl]carbazole hydrobromide (SH 3-28), dose-dependently decreased the maximal rates of cocaine self-administration without affecting comparable responding maintained by food reinforcement. In contrast, a variety of σR antagonists [N-phenethylpiperidine oxalate (AC927), N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(1-pyrrolidinyl)ethylamine dihydrobromide (BD 1008), N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(dimethylamino) ethylamine dihydrobromide (BD 1047), N-[2-(3,4-dichlorophenyl) ethyl]-4-methylpiperazine dihydrochloride (BD 1063), and N,N-dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]-ethylamine ...

Chemicals causing musty smells are mostly produced by Actinomycetes, Streptomyces, Cyanobacteria and other bacteria, fungi and algae. Examples of compounds responsible for musty odor are Geosmin (muddy, resembling damp soil, produced by Streptomyces), trichloroanisole (TCA, smelling like damp cellar, usually produced from chlorinated phenolic compounds by Aspergillus, Penicillium, Actinomycetes, Botrytis cinerea, Rhizobium, or Streptomyces), tribromoanisole (TBA, produced from brominated phenolic compounds by the same bacteria), dimethylmethoxypyrazine (obnoxious musty odor that might be caused by Pseudomonas and Actinobacteria), 2-methylisobomeol (earthy, peat-like), 3-methylbut-2-ene-1-thiol, cis-3-octenal, nonanal, decanal. ...

Shop anise seed essential oil at Mountain Rose Herbs. Steam distilled from the seeds of Pimpinella anisum, anise oil has a lovely sweet and licorice-like aroma. Available in retail and bulk sizes.

1,3,5-三甲氧基苯 1,3,5-Trimethoxybenzene 是中国玫瑰品种中的主要芳香化合物。1,3,5-Trimethoxybenzene 在三个连续的甲基化步骤中由间苯三酚 (初始前体) 合成。1,3,5-Trimethoxybenzene 是一种有效的镇静剂 ...

Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice ...

The licorice-flavored star anise fruit is an ingredient (along with cinnamon, cloves, fennel and pepper) in the five-spice seasoning widely used in Chinese cuisine. Its used to spice up meat

80221-70-1 - IFUNXTQABKIRMP-UHFFFAOYSA-N - Quinoline, 4-(2-(4-piperidinyl)ethyl)-, monohydrochloride - Similar structures search, synonyms, formulas, resource links, and other chemical information.

Lysine (L) - Pure USP Granular Amino Acid (L-Lysine Monohydrochloride), 55 lb by Prescribed For Life at Heartburn Relief Prix. MPN: lysine-55lb. Hurry! Limited time offer. Offer valid only while supplies last. L-Lysine is an amino acid - one of the building blocks of protein - that plays an important function in body development and overall health, and is

104813-25-4 - QXSHFYIDEWCTHQ-UHFFFAOYSA-N - 11H-Indeno(1,2-b)quinolin-11-one, 10-amino-, monohydrochloride - Similar structures search, synonyms, formulas, resource links, and other chemical information.

Glentham Life Sciences is a supplier of GM7239 - DL-Histidine monohydrochloride monohydrate (123333-71-1). Find catalogue prices, chemical data, technical specifications and MSDS documents.

The CSV is a delimited data format that has fields/columns separated by the semicolon character and records/rows separated by newlines. Fields that may contain a special character (semicolon, newline, or double quote), are enclosed in double quotes. For an easier handling, the list of Pre-registered substances is available in four parts ordered by EC number. They contain the same information as the following full list.. ...

Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice ...

Product name: Fragrance and Flavor Musk Xylol , Musk Xylene sale / CAS 81-15-2 Synonyms 2,4,6-Trinitro-1,3-dimethyl-5-tert-butylbenzene; 2,4,6-Trinitro-5-tert-butyl-1,3-xylene; 5-tert-Butyl-2,4,6-trinitro-m-xylene CAS No.: 81-15-2 EINECS: 201-329-4 Molecular formula: C12H15N3O6 Molecular weight: 297.27 Appearance: White crystalline powder Melting point: 112.5-114.5°C Assay :96%min ...

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Star Anise Essential Oil Profile includes uses, constituents, aromatic description, extraction method, latin name, safety info and references.

You are viewing an interactive 3D depiction of the molecule 7-methoxy-1-methyl-2-nitronaphtho[2,1-b]furan (C14H11NO4) from the PQR.

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Naphtho[1,2-b]furan/ACM234037 can be provided in Alfa Chemistry. We are dedicated to provide our customers the best products and services.

Anise is sweet and very aromatic, distinguished by its characteristic flavour.[7] The seeds, whole or ground, are used for preparation of teas and tisanes (alone or in combination with other aromatic herbs), as well as in a wide variety of regional and ethnic confectioneries, including black jelly beans, British aniseed balls and troach drops,[18] Australian humbugs, New Zealand aniseed wheels, Italian pizzelle, German Pfeffernüsse and Springerle, Austrian Anisbögen, Dutch muisjes, New Mexican bizcochitos, and Peruvian picarones. It is a key ingredient in Mexican atole de anís and champurrado, which is similar to hot chocolate, and it is taken as a digestive after meals in Pakistan and India. The Ancient Romans often served spiced cakes with aniseed called mustaceoe[19] at the end of feasts as a digestive. This tradition of serving cake at the end of festivities is the basis for the tradition of serving cake at weddings.[20]. ...

Anise is sweet and very aromatic, distinguished by its characteristic flavour.[7] The seeds, whole or ground, are used for preparation of teas and tisanes (alone or in combination with other aromatic herbs), as well as in a wide variety of regional and ethnic confectioneries, including black jelly beans, British aniseed balls and troach drops,[17] Australian humbugs, New Zealand aniseed wheels, Italian pizzelle, German Pfeffernüsse and Springerle, Austrian Anisbögen, Dutch muisjes, New Mexican bizcochitos, and Peruvian picarones. It is a key ingredient in Mexican atole de anís and champurrado, which is similar to hot chocolate, and it is taken as a digestive after meals in Pakistan and India. The Ancient Romans often served spiced cakes with aniseed called mustaceoe[18] at the end of feasts as a digestive. This tradition of serving cake at the end of festivities is the basis for the tradition of serving cake at weddings.[19] ...

Available brands for generic Anise Oil combination with manufacturers details. Click on the desired brand to find out the drug price.

Perennial plant of the Umbelliferae family of up to 50 cm in height. Stems erect, pubescent, rounded and striated arising from a woody root. Leaves petiolate, the lower heart-shaped and lobed, 2-5 cm in length, the upper lanceolate-linear, and very divided. White flowers about 3 mm in diameter, together in umbels, with long stalks, with five petals. Fruit of 3-5 mm in diachenium, aromatic and provided with 5 rows.. It comes from the east of Europe in the zone that at the moment includes the Middle East, Turkey, Egypt, the Greek Greece and islands, where it grows wild. At present it appears as species cultivated in many warm regions of the world although it is very difficult to become naturalized outside his place of origin and it is only cultivated from seeds planted in the month of April. Between the main producers of the world one is Turkey, China, India, Mexico, Spain and Germany. Anise of better quality is produced in Spain.. ...

One of the prettiest by far…star anise is native to China and Vietnam and is used in both sweet and savoury dishes. It combines particularly well with poached fruit, pork and duck, soups and stews. Best used with a moist heat application added at the beginning of cooking and simmering gently to release a delicious liqu

The fruit of star anise is sweet, stimulant, peptic, purgative, expectorant and anodyne. Its use checks vatta disorders. It passes the urine out easily.

The CpCo(CO)2-catalyzed cocyclization of 1,2-diethynyl- 4-methoxybenzene with alkynes can be applied to the synthesis of spacer-naproxen [2-(6-methoxybiphenylen-2-yl)propanoic acid] and its 7-methoxy isomer, spacer-isonaproxen. While unsymmetrical alkynes are incorporated without regioselectivity, the methoxy group in 6-methoxy-2,3-bis(trimethylsilyl)biphenylene directs electrophiles to C-3, thus allowing for regiochemical differentiation between the 2- and 3-positions.