Activists Against Animal Experimentation. The Activist Against Animal Experimentation is resolved to end the use of animal testing for medical, cosmetic and household purposes etc,. We post petitions, news, stories and info regarding animal testing. Please join up and help the cause! (Animals & Pets)
The ethical treatment of animals is one of serious academic interest today. Specifically, both the practice of animal experimentation and ethical concerns about it have a long history, going virtually back to the ancient Greek period and continuing to the present day. With new breakthroughs in science and technology, it is likely that this practice will be with us for a long time to come. Thus, this book provides an interdisciplinary approach to the topic by utilizing the insights of cognitive ethology, philosophy, science, and Christian theology in order to present a benign approach to the ethical treatment of experimental animals. The reality and existence of animal minds, animal pain, and animal suffering provide the foundation for animal rights, and subsequently, for more positive treatment. Concrete suggestions are offered with regard to more humane animal legislation, improved animal husbandry conditions, as well as concrete guidelines that offset the burdens to animals against the benefits to
Abstract Public acceptance of genetic modification (GM) technologies may be essential to their continued development, yet few studies have investigated the manner in which demographic and educational factors predict support for GM research. The current study examined attitudes toward animal research and GM in ~400 university undergraduates enrolled in introductory or upper-level psychology courses with material on animal experimentation. Results revealed that men were more accepting of animal and GM research than were women. Enrollment in upper-level psychology classes that addressed specific topics in animal research did not directly predict support for GM research, but such enrollment was associated with increased endorsement of the validity of animal research, which then contributed to acceptance of GM scenarios. The current findings highlight the impact of educational variables on support for animal research, which may then influence attitudes toward GM research.
Animal experimentation is a crucial component of scientific research and education. Most advances in modern biomedical science can be traced back to original studies in animals. The university continues to support this critical research while fully appreciating its additional complexities.. All animal research must be approved by the universitys Institutional Animal Care and Use Committee (IACUC), which works close with the Comparative Medicine-Laboratory Animal Facilities (CM-LAF) to help researchers develop effective and compliant protocols. ...
Animals And Their Rights!! Essay, Research Paper What is animal experimentation? Scientific researchers use animal experimentation for biomedical and veterinary research to enhance human health and possibly the welfare of other animals. They claim that successful medical treatments including antibiotics, vaccines and other drugs have been developed with the aid of animal experiments, and such research a crucial means of investigation of and the development of treatments for serious diseases.
Some governments provide detailed information on the number of animal experiments carried out each year. In the United Kingdom, for instance, the annual report
The ideas of cybernetics, and especially that of feedback control, have impressed themselves on society in many ways, of which factory automation is only one. Self-monitoring, or self-awareness, is one of the central components of human individual intelligence (Halstead, 1947; Russell and Russell, 1957, and in press). The notion has been grasped at the sociological level. In industry and commerce it is becoming a routine measure for any large organization to devote considerable staff and expense to the monitoring of its own activities (cf. Meier, 1956). We are, therefore, disposed to expect a large and comprehensive literature of sources on the subject of animal experimentation (cf. Russell, in press, a). For it seems reasonable to suppose that science itself must adopt the principle of informative feedback, and animal experimentation in this country alone is an industry running to millions in commercial terms.. It is therefore surprising to discover the relative dearth of this sort of ...
The Critical Cat interview with Stop UBC Animal Research to investigate how prolific animal experimentation is at UBC and what they are doing to fight it.
The Animal Protection Center of Southeastern Massachusetts is a non-profit organization that serves the animals and people of the community.. Our adoption center serves to care for and re-home homeless pets. Dogs, cats, rabbits, small mammals and birds all benefit from the attention and love provided by our dedicated staff and volunteers.. The Animal Protection Center of Southeastern Massachusetts also strives to help pet owners take the best care of their pets by providing resources such as training, low-cost vaccination and microchip clinics, and humane education outreach to children. ...
It is now more than 20 years since both Council of Europe Convention ETS123 and EU Directive 86/609?EEC were introduced, to promote the implementation of the Three Rs in animal experimentation and to provide guidance on animal housing and care. It might therefore be expected that reports of the implementation of the Three Rs in animal research papers would have increased during this period. In order to test this hypothesis, a literature survey of animal-based research was conducted. A randomly- selected sample from 16 high-profile medical journals, of original research papers arising from European institutions that featured experiments which involved either mice or primates, were identified for the years 1986 and 2006 (Total sample = 250 papers). Each paper was scored out of 10 for the incidence of reporting on the implementation of Three Rs-related factors corresponding to Replacement (justification of non-use of non-animal methods), Reduction (statistical analysis of the number of animals ...
Tomo Editorial and HSI launched Animal Experimentation: An Obstacle to Scientific Progress, a book providing an in-depth analysis of animal use in research from a scientific and historical perspective. The book is part of a growing movement among the Brazilian and international scientific community questioning the effectiveness of animals as models of human biology and disease.
Al-Awar A.; Alm?si N.; Szab? R.; Takacs I.; Murlasits Z.; Sz?cs G.; T?r?k S.; P?sa A.; Varga C.; Kupai K.... more authors ... less authors ...
In 1985, the U.S. Interagency Research Animal Committee (IRAC) advised that "unless the contrary is established, investigators should consider that procedures that cause pain or distress in human beings may cause pain or distress in animals"(http://www.aclam.org/pub_pain_distress.html). Accordingly, the humane use of research animals requires adequate veterinary medical care during animal experimentations and includes the prevention or the alleviation of pain associated with procedural or surgical protocols (clinical pain). Guidelines on the recognition of pain are accepted by researchers but often not so easy to put into practice, especially with mice, the most frequently used laboratory animals. Why?. Mice live in constant fear of falling prey to their enemies, therefore they are prone to show as few signs of disease, suffering or weakness as possible [2-4]. Accordingly, during animal experiments, or even when a person is simply present in the room, the mouse will hide almost all signs of ...
In 1985, the U.S. Interagency Research Animal Committee (IRAC) advised that "unless the contrary is established, investigators should consider that procedures that cause pain or distress in human beings may cause pain or distress in animals"(http://www.aclam.org/pub_pain_distress.html). Accordingly, the humane use of research animals requires adequate veterinary medical care during animal experimentations and includes the prevention or the alleviation of pain associated with procedural or surgical protocols (clinical pain). Guidelines on the recognition of pain are accepted by researchers but often not so easy to put into practice, especially with mice, the most frequently used laboratory animals. Why?. Mice live in constant fear of falling prey to their enemies, therefore they are prone to show as few signs of disease, suffering or weakness as possible [2-4]. Accordingly, during animal experiments, or even when a person is simply present in the room, the mouse will hide almost all signs of ...
While it is important to provide a full explanation of the reasons why animal research and testing is important for modern medicine, it can sometimes be useful to have a handful of short pro animal research one-liners on hand. These work particularly well for Twitter - which is why each of our lines below includes…
Scientists have managed to successfully open and close the protective cover around the brain - the blood-brain barrier - in a human patient as a means for drug delivery, following work in a range of animals including mice and monkeys.
More studies need to be done, but we think theres potentially no limit on the diseases this screening disease could be applied to other than the human imagination,". http://www.diabetes.co.uk/news/2015/aug/zebrafish-embryos-used-to-identify-potential-type-1-diabetes-drugs-95530698.html. 26/08/15. Resveratrol, a chemical found in the skin of grapes (and consequently red wine) may have beneficial cardiovascular effects. However, studies in dogs show varying effects on the immune systems of dogs - increasing and decreasing it in different ways simultaneously.. Axiak-Bechtel said "Seeing a decrease in neutrophil function typically means an immune system is losing the ability to kill invaders like bacteria. Combining this loss of bacteria-fighting ability with an increase in inflammatory cytokines creates a very interesting mixed message in terms of what resveratrol is doing to the immune system.". http://www.alnmag.com/news/2015/08/red-wine-compound-causes-conflicting-changes-dogs-immune-systems ...
BY KURT CUNNINGHAM , JUNE 12, 2009 7:26 AM UI researchers will have a new underground facility to house animals after the state Board of Regents approved an indoor enclosure for $11.2 million at Thursdays meeting.. Scientists hope the new facility - which will cost almost $134 million - will contribute to better research and security.. At 35,000 square feet, the underground lab will connect the Medical Education Research Facility and Carver Biomedical Research Building. It is a late addition to the Institute for Biomedical Discovery - a project the UI has already started. Officials set aside state and federal money in 2007 to be distributed over several years for the initial project. They also received private donations given specifically to the project, said UI spokesman Tom Moore. "Science is important to Iowans," he said. "Dr. George Weiner [the director of the Holden Comprehensive Cancer Center] says there are many research ideas that dont get funded, and a facility such this increases the ...
The new EU directive on the protection of animals used for scientific purposes (2010/63/EU) has been implemented. One of the requirements of the directive is that each breeder, supplier and user of laboratory animals sets up an Animal Welfare Body (AWB, Instantie voor Dierenwelzijn, IvD in The Netherlands). The AWB helps to ensure a responsible animal experimentation policy and is responsible for the a number of tasks: The animal-welfare body shall, as a minimum, carry out the following tasks: Advice the staff dealing with animals on matters related to the welfare of animals, in relation to their acquisition, accommodation, care and use; Advise the staff on the application of the requirement of replacement, reduction and refinement, and keep it informed of technical and scientific developments concerning the application of that requirement; Establish and review internal operational processes as regards monitoring, reporting and follow-up in relation to the welfare of animals housed or used in ...
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Learn all about the field of medical research and experimentation with insightful articles and fascinating updates in the field of medicine. From animal experimentation, clinical trials, biomedicine, and breakthroughs in medical technology, weve got you covered.
Because scientific inquiry involves exploration of the unknown, the outcome of experimental procedures is sometimes unpredictable. In the case of animal experimentation, this may result in situations in which animal health and/or welfare are adversely affected.. Genetically manipulated animals (GMA) provide a good example. Initially, the overall effect(s) of a particular genetic manipulation may be unknown. However, once animals are generated the resulting novel phenotypes may include immune deficiency, metabolic disorders, behavioral abnormalities or other health issues that make those animals more susceptible to disease or distress. GMA lines that exhibit abnormalities in health or behavior often require the establishment of revised husbandry and/or monitoring protocols. Humane endpoints specific for the GMA line may also need to be developed. More information on assessing the welfare of GMA can be found on the NC3Rs site.. In the case of a new GMA line it is recommended that the first ...
It is my pleasure to welcome you to join us at the Noguchi Memorial Institute for Medical Research (NMIMR), Ghanas leading biomedical research institute at the University of Ghana. The Institute has over the years embarked on a series of initiatives to upgrade its research infrastructure and human capacity to attract the worlds best scientists, technologists, postdoctoral fellows, postgraduate students, undergraduate interns, and health professionals through training and experiential learning. Our community continues to grow and we are happy to share our research, training and learning experience with you.. At the NMIMR, we conduct both laboratory and field-based research into communicable and non-communicable diseases of public health importance; led by researchers in nine departments of the institute, namely Animal Experimentation, Bacteriology, Clinical Pathology, Electron Microscopy and Histopathology, Epidemiology, Immunology, Nutrition Parasitology, and Virology. Whether you are a ...
Andy Maniotis (University of Iowa), American Journal of Pathology, 1999 Cancer! Its our Grim Reaper, todays Black Death, a dark and terrible health threat and destroyer of lives. We hear about it, read about it, and fear it more deeply than any other present disease. Ominously, projections indicate that one in every five of us will die of cancer, and 40 percent of us will have a diagnosis of cancer sometime in life. Considering that there are more than 200 different forms of human cancer alone, the hope for a magic bullet that will cure all is just pie in the sky. The disease first went political in 1971, when the Nixon administration declared the War on Cancer. We all know the war has not yet been won, even with billions poured into it every year. In fact, cancer deaths have increased steadily. This humiliating defeat is in large part due to our addiction to animal experimentation. It is an open secret in scientific circles that animal-modeled biomedical research yields results that cant ...
Animal experimentation and the models by which it is conducted are a core component of the Preclinical Translational Research Units work. Animal models are the primary mode of research responsible for translating preclinical project work into successful clinical trials, which is why they are a focus of our unit.. We work to create animal models that minimize the consumption of resources, especially time and money, without allowing for any compromise in the integrity of our data or their reproducibility. By continually striving to uphold these standards while continually striving to assess and improve our animal models we ensure that we consistently deliver optimum results and solutions.. Under the Duke Preclinical Translational Research Units expert guidance we hope to be able assist our partners in designing the model and method that allow for the creation of experiments that run correctly the first time, reducing waste and repetition.. We employ the following animal types for our animal ...
Science Institutions are concerned with their public image, which often determines their funding, so that they are often keen to be seen to promote public dialogue and engagement.. . Many government departments are interested in science education, training teachers, etc. Often they have funds for specific public projects like adult learning, animal experimentation, synthetic biology etc.,. . Many cultural and artistic groups are now including science in their agendas, since human sciences are questioning the traditional views of art, philosophy, literature, etc. So Arts centres are often keen to adopt SciCafes.. . As for schools cafes, it is clear that science education is in crisis almost everywhere in the world, so that new ideas are widely acceptable. Approaching teachers, individual schools and education authorities is a fairly easy way to start Cafes in schools - although it is more difficult to keep them free from the hierarchy within the school.. So in many ways the Cafes can build ...
First, it is interesting per se, to find common psycho-physiologic grounds between our and other animals behaviour and "psyche." Second, such commonality allows us to explore new ways (treatments, drugs) for dealing with human suffering (anxieties, depressions, phobias etc.). I do not know of any other procedure or behavioural test, or physiological index, that compares anxiety and relief, which would provide 20-fold (2000%) difference in objective measurements (it is usually measured in fractions, like 35% or so). Our rats sigh approx. 25 times/hour spontaneously, less than 10/h when anxious, but more than 180/h when relieved! So, consider, if you really have experimental animals` wellbeing in mind and not just negative feeling about any animal experimentation, that far fewer animals will be required to test a new psychotropic drug or some other procedure, when measuring emotional states (using sighs instead of heart rate, blood pressure etc.) is so dramatically improved (as demonstrated by ...
St. Lukes-Roosevelt Institute for Health Sciences, New York, NY - Facility Reports and Information - Resources and Links From Stop Animal Exploitation NOW! (SAEN) - Exposing the truth to wipe out animal experimentation
University of Akron cited in the deaths of 2 voles in research lab - Media Coverage - Stop Animal Exploitation NOW! - Exposing the truth to wipe out animal experimentation
new approaches for a new millennium. (beginning narration). Education and training in the life sciences require that students learn a diversity of skills as well as the traditional knowledge base.. Graduates who enter the professions must be familiar with the technology employed in todays laboratories and clinics, and with the design and performance of experiments.. Of equal importance is the ability to communicate well with patients, and the sensitivity to appreciate complex ecological systems.. Some will also need hands-on experience of animals and animal tissue for their careers.. All students of biological science and veterinary and human medicine perform practical work to illustrate knowledge and to gain a number of these skills, practical work which for some involves dissection and animal experimentation.. But the tools and approaches used by teachers are evolving in response to developments in technology and the demands of students and society itself.. In this film, we investigate new ...
BALB/c is an albino, laboratory-bred strain of the house mouse from which a number of common substrains are derived. Now over 200 generations from New York in 1920, BALB/c mice are distributed globally, and are among the most widely used inbred strains used in animal experimentation. The founding animals of the strain were obtained by Halsey J. Bagg of Memorial Hospital, New York, from a mouse dealer in Ohio in 1913. From 1920, the progeny of the original colony were systematically inbred, sibling to sibling, for 26 generations over 15 years. During this time, the colony passed through the care of a number of scientists, including C.C. Little and E.C. MacDowell at the Carnegie Institution of Washington and H.J. Muller at the University of Texas at Austin. By 1935 the animals were in the possession of Mullers student, George Davis Snell, who moved them to The Jackson Laboratory. This stock provided the basis of all the BALB/c substrains that are now in use around the world. Snell provided some ...
​The Center For Ethical Science (CFES) is a non-profit animal advocacy organization dedicated to: educating the public on the inefficacy of invasive animal experimentation; exposing how tax dollars pay for much of it and what we can do to help eliminate it; and promoting effective and humane ways of conducting scientific and cosmetic research.
The effect of nitrogen oxides on immunity was examined in animal experimentation and in clinical trials. In guinea pig, immunity was found to be lowered following 6 months exposure to 1 ppm; there...
All advances in medicine have an underlying basis in biomedical research. Animal research is done with great care and is done with special concern for the ethical treatment of the animals. The importance of medical research lies in the fact that new knowledge in medicine and innovative development is going to take place only when medical research is done." -Michael E. DeBakey, Jr., M.D. (Legendary Heart Surgeon and Inventor ...
This recognition is now prompting some AIDS activists to argue that experiments with other species are holding back the development of safer, more-effective anti-HIV drugs. One of Britains top researchers, Prof. Robin Weiss, has expressed serious doubt that information gathered from studies of laboratory animals can help illuminate the mechanisms by which HIV sabotages the immunity of humans. Another senior AIDS doctor in Britain has described the millions of dollars spent on animal research as ...
Scientists are quickly pointing out that the use of a single inbred mouse strain as was the case in this study, is not representative. Furthermore it is known that certain inbred mouse strains are resistant to septic shock, whereas others are much more susceptible. So yes the use of a certain inbred mouse strain in one study failed to translate into medicines for mankind and illustrates the limits of this particular strain for a given research or disease, however in my mind the article also reminds us of the importance of choosing the adequate or most valid animal model for a study. If I am not mistaken certain countries demand the use of two different animal species in studies such as for example rodents and primates. I now better understand the logic behind such a policy ...
Medical advancement, animal research, nonhuman primates, air transport, live animal cargo, pharmaceutical research, Opinion based blog.
ANIMAL RESEARCH ACT ……. 20 YEARS ON. the journey begins…. 1978 - Australian Veterinary Assoc receives brief from NSW government * Separate legislation * Comprehensive review of existing legislation * Ontario legislation as model * Extensive consultation. Slideshow 68142 by Philip
Supporters of animal research do their cause no good by justifying such work solely on the grounds that it helps to find cures for disease. The benefits are much broader
... , formerly Annales de Zootechnie, publishes original articles, reviews, notes and symposium proceedings concerning research on farm animals
... plays an important role in some of our work. While we make every effort to keep their use to a minimum, some research can only take place with the use of animals.
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Safranin is used as a dye for textiles and as a stain for various scientific procedures. Scientific procedures that involve safranin include Gram counterstaining, endospore counterstaining, granule...
REFERENCES 1. Flegal KM. The obesity epidemic in children and adults: current evidence and research issues. Med Sci Sports Exerc. 1999; 31: S509-S514. 2. Bertram CE, Hanson MA. Animal models and programming of the metabolic syndrome. Br Med Bull. 2001; 60:103-21. 3. Buschard K. The Use of Diabetic Animal Models. Meet A Research Group. Diabetes Research Group, Bartholin Instituttets, Copenhagen, Denmark. Scand J Lab Sci. 2001; 28: 58-58. 4. Kaplan JR, Wagner JD. Type 2 Diabetes - An Introduction to the Development and Use of Animal Models. Institute for Laboratory Animal Research (ILAR) Journal. 2006; 47(3):181-185. 5. American Diabetes Association. Diagnosis and Classification of Diabetes Mellitus. Diabetes Care. 2008; 31: S55-S60. 6. Srinivasan K, Ramarao P. Animal models in type 2 diabetes research: An overview. Indian J Med Res. 2007; 125: 451-472. 7. Okamoto J, Kanemoto N, Ohbuchi Y, Okano M, Fukui H et al. Characterization of STZ-induced type 2 diabetes in Zucker fatty rats. Exp. Anim. ...
of the Shared Resource The Animal Resources Center (ARC) provides a comprehensive, centralized animal care program in support of laboratory animal research at S...
By Emily Sena. 374 interventions have been reported to be effective in experimental stroke; 97 were tested in clinical trials but only one of these was shown to be effective. The principle of drug development goes that if a therapy improves outcome in animals the next step is to test it in humans in a clinical trial, with the hope that important improvements in outcome will be seen. The reality is that there are huge amounts of animal data (too many drugs), from experiments that are not designed with sufficient rigour or adequately reported, and important improvements in outcomes are usually not seen in clinical trials (too few medicines). Many animal experiments are failing in their objective effectively to inform human health.. And there are a lot of drugs around - in 2013, 350 publications describing animal experiments were published every day! I understand that the average life scientist has neither the desire nor the need to consume this amount of information, but even within a limited ...
Stop Animal Exploitation Now (SAEN), a national organization that monitors animal laboratories, has recently released information contained in documents and photos that were obtained from the University of Washington, Seattle. These photos and documents paint a vivid picture of the harsh reality daily inflicted on primates within this lab without even delving into gruesome experimental…
The Physiologic Core (C) will be located in the Division of Animal Laboratory Resources within dedicated space at the University of Kentucky. This core will pro...
Animal protection and welfare is an area many people are passionate about, veganism and illuminating issues relating to live exportation being two examples of recent concern. How did you become so passionate in the realm of animal protection and welfare?. I think wanting to protect animals is in my DNA! I come from a family that respects and cares about animals, and I feel this way myself. From volunteering at my local animal shelter as a student to being able to commit myself full-time to this important work, animals have always been my thing. Thinking about our dogs work specifically, what really moves me is the dogs Ive seen that have never had a home or someone to love them, and that have suffered sometimes terrible hardship, but that still show kindness and hope … their tails are still wagging! Its incredibly motivating to encounter such dogs and to know that I can help to create better lives not only for them, but also the communities in which they live.. What role does the human ...
I think someone has completely missed the point I was trying to make: the suffering of animals I was referring to was not the seals, the stray cats, or the humans but rather the animals who are negatively affected by those three species. I am trying to point out that the most effective way to help the most amount of individual animals to live a happy healthy life is to give them somewhere to live that is not decimated by invasive animals out to kill them (including humans... a naked ape that was never meant to live outside some tropic jungle but here we are in every habitat destroying homes of all other species ...
Due to the aforementioned differences between humans and animals as well as the artificially induced symptoms, it is not surprising that in spite of intensive animal experiments during the last 150 years two thirds of all diseases are still not curable in humans, nor are their causes known. (32) According to a review, none of 119 cures promised during the last 30 years has been fulfilled. (33) No other scientific method is as unreliable and unpredictable as animal experiments. What animals - and which species - react exactly the same way to a substance as humans only becomes apparent after testing on humans. Animal testing has never been validated, but has still been the "gold standard" in biomedical science for decades. That applies nowhere else, so why is it accepted in the important area of human health? After being tested on animals, new therapies need to be tested on humans in clinical trials to determine their safety and efficacy. Due to the poor transferability of the animal-based results ...
If youre like most pet owners (or, if you prefer, "pet parents"), you would do everything in your power to make sure your companion animals are healthy and well cared for. If youre like most animal lovers, you support efforts to prevent the spread of devastating diseases that affect wildlife.. Many, perhaps even most, first-time pet owners quickly learn how many diseases and conditions-surprise!-affect our four legged friends just as they do people. Dogs can get urinary tract infections and cancer; cats can develop cataracts and hyperthyroidism. But fear not. Researchers have developed treatments for even many of the more serious and life-threatening health problems that affect pets-often using the same medications and procedures used to treat their human counterparts.. Meanwhile, scientists and conservationists are working diligently to curb the rate of infectious diseases, from sylvatic plague to Lyme disease, that would otherwise decimate populations of animals living in the wild (including ...
May 8, 2017. CAARE continually reviews scientific methods of research without using animals. Now and again we are excited to see something truly innovative that shows important potential to replace animals.. At the laboratory of Maikel Rheinstadter, associate professor of biophysics at McMaster University, he and his team are using basic biological components, like lipids, cholesterol, peptides and proteins to form synthetic, human-like tissue in a petri dish, entirely without the use of animals or animal cells. These synthetic tissues can be used to study how drugs work, including how and why they work differently between individuals.. The ground-breaking technique has far-reaching applications for enhancing personalized medicine, as well as expediting drug discovery by reducing the use of animal or human testing.. The need for improved methods of drug development is essential. The FDA describes the current process, which is based largely on animal testing, as "complicated, time-consuming and ...
Karolinska Institutets remit is to help improve human health through research and education. We achieve this with both basic research to understand biological mechanisms and more patient-based research to produce new forms of treatment.
The unicellular ancestor of animals may have harbored some of the molecular tools that its many-celled descendants use to coordinate and direct cell differentiation and function, scientists show.. 0 Comments. ...
The Nutshell Putative Gay Genes Identified, Questioned A genomic interrogation of homosexuality turns up speculative links between genetic elements and sexual orientation, but researchers say the study is too small to be significant. ...
Well, according to New Scientist, a brand new technique for repairing a damaged spinal cord has been proven to restore walking in paralyzed rats - in just a matter of days. Within minutes after undergoing this operation, paralyzed rats could move previously non-functioning limbs. After about a month, most of the rats had regained 60 to 70 percent of their leg function. This incredible study gives scientists hope that one day a similar operation could be performed on people who are paralyzed and that they too could regain function of their limbs ...
About the size of a pencil eraser, the model was created by reprogramming adult human skin cells into stem cells that subsequently could be engineered into neural cells.. The brain organoid took 15 weeks to develop and contains all the key areas of the brain, including a spinal cord, a complex of neural cells, normal cell signaling mechanisms and a retina. The model does not contain any vascular system to allow for blood flow, though Dr. Anand says thats a goal. "If we let it go to 16 or 20 weeks, that might complete it, filling in that 1 percent of missing genes. We dont know yet," he said.. Dr. Anand and his research associate Susan McKay have begun to use the platform to create organoid models of Alzheimers, Parkinsons and autism in a dish.. "Its a scalable model that can be engineered to carry the genetic variants that give rise to all these diseases … and it gives us incredible access to things we never have done before," Dr. Anand told The Washington Post. "We can screen drugs, we ...
Animal Research, formerly Annales de Zootechnie, publishes original articles, reviews, notes and symposium proceedings concerning research on farm animals
Clinical examination is a fundamental part of the process of veterinary diagnosis. Without a proficient clinical examination and an accurate diagnosis it...
Any comparison between life at the end of the last century and life at the end of this one would highlight the enormous advances in medicine which many people nowadays take almost for granted.
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This product group includes immunoassays for the determination of various hormones (steroid and protein-based hormones) from different animal species like rat and mouse (murine), dogs (canine), and horse (equine).. ...
A randomized controlled trial (RCT) is a scientific procedure most commonly used in testing medicines or medical procedures. RCTs are considered the most reliable form of scientific evidence because it eliminates all forms of spurious causality. RCTs are mainly used in clinical studies, but are also employed in other sectors such as judicial, educational, social research. Clinical RCTs involve allocating treatments to subjects at random. This ensures that the different treatment groups are statistically equivalent. Sellers of medicines throughout the ages have had to convince their consumers that the medicine works. As science has progressed, public expectations have risen, and government health budgets have become ever tighter, pressure has grown for a reliable system to do this. Moreover, the publics concern for the dangers of medical interventions has spurred both legislators and administrators to provide an evidential basis for licensing or paying for new procedures and medications. In ...
Free Essay: Mainly this article is focused on what will help wounds of natural clotting.There is an assumption based on scientific procedures (based at...
The local police in Granada, Spain received a call from a concerned resident of a nearby village: He had found a neglected dog in a dire state. Every minute was a question of life or death for the emaciated dog. The people at the animal protection agency, Albergue de Animales Dog House, immediately got involved and rushed the extremely weak animal to the vet. ...
Urge Korean Prime Minister to Strengthen Animal Protection Law by visiting http://www.idausa.org/campaigns/korea/alert_060510.html Despite cultural differences, we must think of dogs as any other...
Learn about the key aspects of experimentation as a research method in science. Includes information on manipulating variables and controls.
Tek-Event is company which understands the need for personalised service to the human IVF laboratories, animal research and veterinary ART facilities.
Dr. Plechners Corner is a compilation of veterinary and animal research articles by Al Plechner, DVM. Some of the articles found in this section are al
Dr. Plechners Corner is a compilation of veterinary and animal research articles by Al Plechner, DVM. Some of the articles found in this section are al
Animal research is of course vital in the development of medicines to treat animals. Animals benefit from the medicines developed initially for people
NO is actually a vital regulator of vascular function in health and condition with effects on vascular tone, platelet purpose, and endothelial perform. The donation of additional NO by pharmaceutical brokers is a feasible usually means of influencing vascular purpose and cardiovascular outcomes. The not too long ago created CINODs stand for an enjoyable new course of agent that show assure inside the pharmacological management from the ache linked to osteoarthritis, getting at least as effective as NSAIDs in animal research so far. They have also shown some likely for being simpler, supplied the effects of NO on soreness notion, whilst also supplying supplemental benefits which include increased gastric protection. This may boost pain Command in osteoarthritis ...
UW-FHCRC Animal Bioimaging Center (ABIC) Bioimaging involves the use of technologies to view samples from animals that cannot be seen to the unaided eye. Such imaging equipment includes magnetic resonance imaging (MRI), micro positron emission tomography (PET), ultrasound, optical imaging, SPECT/gamma camera, and micro computed tomography (CT). They are used in many animal research projects,…
The sugar industry funded animal research in the 1960s on sugars effects on heart health, then buried data suggesting sugar could be harmful.
Under this document animals will continue to be experimented on, in large numbers, for reasons which have nothing to do with finding cures for diseases - PLEASE urge MEPs to take a much stronger line and ensure that the future legislation introduces ...
Conversion optimization is hard, but the heaviest lifting is often organizational - changing an organization from a gut-based approach to one driven by dat
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.. ...
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.. ...
If a team of Harvard bioengineers has its way, animal testing and experimentation could soon be replaced by organ-on-a-chip technologies ...
One thing thats been bothering me is how the mc campaigners seem to focus almost exclusively on animal rights over people rights in the Third World. For example, their picketing of mcDonalds sights seems focused exclusively or gives priority to animal rights. It seems silly and unethical to me to give this kind of priority to animal rights over native peoples rights.. I dont think it helps the campaign when its seen as an animal rights issue. As an animal rights issue, the anti-McD campaign will continue to gain only a small following. People, myself included, will think, why are they going after a restaurant for its treatment of animals ...
Animal welfare and rights in India regards the treatment of and laws concerning non-human animals in India. It is distinct from animal conservation in India. India is home to several religious traditions advocating non-violence and compassion towards animals, and has passed a number of animal welfare reforms since 1960. India is also one of the worlds leading producers of animal products. Indias first national animal welfare law, the Prevention of Cruelty to Animals Act, 1960, criminalizes cruelty to animals, though exceptions are made for the treatment of animals used for food and scientific experiments. The 1960 law also created the Animal Welfare Board of India to ensure the anti-cruelty provisions were enforced and promote the cause of animal welfare. Subsequent laws have placed regulations and restrictions on the use of draught animals, the use of performing animals, animal transport, animal slaughter, and animal experimentation. The Breeding of and Experiments on Animals (Control and ...
 Animal rights is the position that animals should not be exploited. Animal rights people believe that animals should not be used for food, clothing, entertainment, medical research, or product testing.
Join NARN ( Northwest Animal Rights Network ) for our monthly #vegan letter writing party! Well be gathering at Wayward Vegan Cafe! Who doesnt want an excuse to eat at Wayward?. Why letter writing? Letter writing is a simple way to make change for the animals! At our letter writing events, we write for many different reasons: opposition to the creation of new animal laboratories, support for sending animals to sanctuary, promotion of vegan events and issues through letters to the media, and raising the spirits of activists and comrades who have been jailed for their pro-animal and political actions!. NARN provides the stationery, pens, stamps, sample letters, and ideas for what to write -- just bring yourself. You can even bring your laptop if youd prefer to type or email your letters!. Come for a little while or spend the whole two hours with us. Yummm - Wayward!. ...
Geriatric animal models are crucial for a better understanding and an improved therapy of age-related diseases. We observed a high mortality of aged mice after anesthesia with a standard dose of ketamine/xylazine, an anesthetic regimen frequently used in laboratory veterinary medicine. C57BL/6-N mice at the age of 2.14 ± 0.23 months (young mice) and 26.31 ± 2.15 months (aged mice) were anesthetized by intraperitoneal injection of 2 mg ketamine and 0.2 mg xylazine. 4 of 26 aged mice (15.4%) but none of 26 young mice died within 15 min after injection of the anesthetics. The weight of aged mice was significantly higher than that of young mice (32.8 ± 5.4 g versus 23.2 ± 3.4 g, p | 0.0001). Thus, aged mice received lower doses of anesthetics in relation to their body weight which are within the lower range of doses recommended in the literature or even beneath. There were no differences between deceased and surviving aged mice concerning their sex, weight and their motor performance prior to anesthesia
This page is administered by the Committee of Public Relations and Information Processing of the Institute of Medical Science, the University of Tokyo. ...
Please ask your US senators and representative to support the Animal Welfare in Agricultural Research Endeavors (AWARE) Act--introduced in response to the horrendous abuse suffered by thousands of animals at the federally funded and operated Meat Animal Research Center in Nebraska. The AWARE Act would require federal farm animal research operations to abide by the Animal Welfare Act.
Introduction. The ethical analysis of our moral obligations to animals, as well as practical decisions regarding many issues in veterinary medicine, both presuppose some account of "animal welfare" - that is, of what makes an animals life go well or poorly. Therefore, it is essential that we think critically about the concept of animal welfare. This paper briefly explores some philosophical issues in the definition and assessment of animal welfare.. Two Different Senses of "Animal Welfare". The first thing to clarify is the way in which Im using the term "animal welfare." In both moral philosophy and ordinary language (as concerns humans), the term "welfare" is roughly synonymous with "wellbeing." To say that an individual "has a welfare" is to say that her life can go better or worse from her perspective, and to talk about her welfare is to talk about her interests - what are the things that make her life go better or worse for her? How should we conceptualize her wellbeing in the abstract? ...
A list of animal research facilities located in Montana and regulated by the United States Department of Agriculture with links to annual reports and inspection reports.
A list of animal research facilities located in Colorado and regulated by the United States Department of Agriculture with links to annual reports and inspection reports.
Clinical follow-up. Six patients were followed up monthly at Tokyo Medical and Dental University Hospital, after a diagnosis of liver cirrhosis by either liver biopsy and/or a combination of clinical features. During monthly visits, they underwent physical examination, urinalysis, and complete blood count, with measurement of serum α-fetoprotein, prothrombin time, activated partial thromboplastin time, and serum chemistry. All patients received a liver ultrasound, magnetic resonance imaging (MRI), and/or computed tomography (CT) at least every 6 mo. The protocol was approved by the Ethical Committee of Tokyo Medical and Dental University.. In vivo human cancer xenograft experiments. CW-2 human colon cancer xenograft experiments were conducted in accordance with the Guidelines for Animal Experimentation, and approved by the Animal Care and Use Committee of Tokyo Medical and Dental University. Male athymic BALB/c Slc-nu mice (Japan SLC) were given free access to sterile rodent chow and water. ...
The broad and long term goal of the Animal Models Core is to provide consistent care, experimental procedures, and husbandry that are important to the success of projects. Each promising investigator has limited animal experimental experience, but needs to verify in vitro findings in vivo. Therefore, the Animal Model Core (AMC) will ensure project experimental consistency, compliance with federal animal welfare regulations, and effective training of project leaders and personnel in animal experimentation. Dr. Hinsdale will serve as the AMC director, and along with technical staff, will provide basic services (e.g. Colony management and husbandry, biosafety containment and housing of animals, infection of animals and harvesting of samples for analyses, and pulmonary function tests). The current experimental animal models will be mice. The four projects that are proposed require mice to further verify in vivo findings arising from the proposed in vitro experiments. In project 1, using some ...
THE ANIMAL PROTECTION ACT - INTERNATIONAL COMPARISONS AND BEST PRACTICES presented by SANDRA GORE and CHARLOTTE NIKSCHTAT. INTRODUCTION. The General Structure of Animal Welfare Legislation The purpose / underlying principles of the legislation Slideshow 68112 by sherlock_clovis
From Natures Correspondence page (Nature 452, 282; 20 March 2008). Animal-welfare extremism is spreading, as reported in your News Story Animal-rights activists invade Europe (Nature 451, 1034-1035; 2008). For example, they blocked plans to build new laboratory facilities in Venray, the Netherlands, with a campaign that included painting threats on the lab directors houses. Although many people are concerned about animal experimentation, most do not understand the rationale behind these illegal activities, which cause considerable fear in the research community. Researchers respond by wanting to reduce transparency and asking the government to increase repression of activists - following the UK example of stricter legislation. Todays understanding of animal welfare and of the motivation underlying both normal and abnormal behaviour indicate that this response could be counterproductive. A better solution would be to channel peoples frustrations into more constructive activities. The ...
A federal oversight agency claims it caught a Vanderbilt researcher falsifying findings on a cancer treatment, according to a September report More ...
Humane endpoints are a core refinement concept in animal experimentation. This paper identifies an urgent requirement for individuals and institutions to refocus on humane endpoints as part of the transposition of Directive 2010/63/EU into the national laws of the Member States, and to go beyond their legal construction when setting new guidance or applying humane endpoints in practice. It will be argued that requirements for humane endpoints within the Directive appear not to promote recent advances in best practice, but seem reliant on a narrow and potentially outdated definition of the term. We describe progress that has been made in encouraging change in the construction and application of humane endpoints, and suggest that Directive 2010/63/EU does not sufficiently acknowledge the conceptual complexity of this refinement strategy. For example, a useful development representing recent consensual views of best practice has been proposed by an EU consortium (in 2012). A complex approach to ...
Return to Top. B. Basic Principles for all Medical Research. It is the duty of the physician in medical research to protect the life, health, privacy, and dignity of the human subject.. Medical research involving human subjects must conform to generally accepted scientific principles, be based on a thorough knowledge of the scientific literature, other relevant sources of information, and on adequate laboratory and, where appropriate, animal experimentation.. Appropriate caution must be exercised in the conduct of research which may affect the environment, and the welfare of animals used for research must be respected.. The design and performance of each experimental procedure involving human subjects should be clearly formulated in an experimental protocol. This protocol should be submitted for consideration, comment, guidance, and where appropriate, approval to a specially appointed ethical review committee, which must be independent of the investigator, the sponsor or any other kind of undue ...