Activists Against Animal Experimentation. The Activist Against Animal Experimentation is resolved to end the use of animal testing for medical, cosmetic and household purposes etc,. We post petitions, news, stories and info regarding animal testing. Please join up and help the cause! (Animals & Pets)
The ethical treatment of animals is one of serious academic interest today. Specifically, both the practice of animal experimentation and ethical concerns about it have a long history, going virtually back to the ancient Greek period and continuing to the present day. With new breakthroughs in science and technology, it is likely that this practice will be with us for a long time to come. Thus, this book provides an interdisciplinary approach to the topic by utilizing the insights of cognitive ethology, philosophy, science, and Christian theology in order to present a benign approach to the ethical treatment of experimental animals. The reality and existence of animal minds, animal pain, and animal suffering provide the foundation for animal rights, and subsequently, for more positive treatment. Concrete suggestions are offered with regard to more humane animal legislation, improved animal husbandry conditions, as well as concrete guidelines that offset the burdens to animals against the benefits to
Abstract Public acceptance of genetic modification (GM) technologies may be essential to their continued development, yet few studies have investigated the manner in which demographic and educational factors predict support for GM research. The current study examined attitudes toward animal research and GM in ~400 university undergraduates enrolled in introductory or upper-level psychology courses with material on animal experimentation. Results revealed that men were more accepting of animal and GM research than were women. Enrollment in upper-level psychology classes that addressed specific topics in animal research did not directly predict support for GM research, but such enrollment was associated with increased endorsement of the validity of animal research, which then contributed to acceptance of GM scenarios. The current findings highlight the impact of educational variables on support for animal research, which may then influence attitudes toward GM research.
Dive into the research topics where Center for Laboratory Animal Research (CLAR) is active. These topic labels come from the works of this organisations members. Together they form a unique fingerprint ...
Animal experimentation is a crucial component of scientific research and education. Most advances in modern biomedical science can be traced back to original studies in animals. The university continues to support this critical research while fully appreciating its additional complexities.. All animal research must be approved by the universitys Institutional Animal Care and Use Committee (IACUC), which works close with the Comparative Medicine-Laboratory Animal Facilities (CM-LAF) to help researchers develop effective and compliant protocols. ...
Animals And Their Rights!! Essay, Research Paper What is animal experimentation? Scientific researchers use animal experimentation for biomedical and veterinary research to enhance human health and possibly the welfare of other animals. They claim that successful medical treatments including antibiotics, vaccines and other drugs have been developed with the aid of animal experiments, and such research a crucial means of investigation of and the development of treatments for serious diseases.
This course provides a broad overview of diverse topics in the practice of and approaches to humane animal experimentation. It addresses such issues as experimental design (including statistics and sample size determination), humane endpoints, environmental enrichment, post-surgical care, pain management, and the impact of stress on the quality of data. It was developed by CAAT director Alan Goldberg and James Owiny, the training and compliance administrator of the Johns Hopkins University animal care and use committee, along with Christian Newcomer, associate provost for animal research and resources at Hopkins ...
Some governments provide detailed information on the number of animal experiments carried out each year. In the United Kingdom, for instance, the annual report
TY - JOUR. T1 - Predictive value of in vitro assays depends on the mechanism of toxicity of metal oxide nanoparticles. AU - Cho, Wan-Seob. AU - Duffin, Rodger. AU - Bradley, Mark. AU - Megson, Ian L. AU - Macnee, William. AU - Lee, Jong Kwon. AU - Jeong, Jayoung. AU - Donaldson, Ken. PY - 2013/10/25. Y1 - 2013/10/25. N2 - Hazard identification for risk assessment of nanoparticles (NPs) is mainly composed of in vitro cell-based assays and in vivo animal experimentation. The rapidly increasing number and functionalizations of NPs makes in vivo toxicity tests undesirable on both ethical and financial grounds, creating an urgent need for development of in vitro cell-based assays that accurately predict in vivo toxicity and facilitate safe nanotechnology.. AB - Hazard identification for risk assessment of nanoparticles (NPs) is mainly composed of in vitro cell-based assays and in vivo animal experimentation. The rapidly increasing number and functionalizations of NPs makes in vivo toxicity tests ...
The ideas of cybernetics, and especially that of feedback control, have impressed themselves on society in many ways, of which factory automation is only one. Self-monitoring, or self-awareness, is one of the central components of human individual intelligence (Halstead, 1947; Russell and Russell, 1957, and in press). The notion has been grasped at the sociological level. In industry and commerce it is becoming a routine measure for any large organization to devote considerable staff and expense to the monitoring of its own activities (cf. Meier, 1956). We are, therefore, disposed to expect a large and comprehensive literature of sources on the subject of animal experimentation (cf. Russell, in press, a). For it seems reasonable to suppose that science itself must adopt the principle of informative feedback, and animal experimentation in this country alone is an industry running to millions in commercial terms.. It is therefore surprising to discover the relative dearth of this sort of ...
I have often said that one way animal models are used in research and testing is to predict human response to drugs and disease. Some have challenged this.
The Critical Cat interview with Stop UBC Animal Research to investigate how prolific animal experimentation is at UBC and what they are doing to fight it.
The in vivo evaluation of a material to be used in clinics is a long trial and requires a well planned sequence of steps. In vivo tests are complementary to those performed in vitro that provide necessary and useful results to be added to those found in the in vivo testing, and strongly reduce the number of animals used. Animal studies require first of all the compliance to the ethical and legal rules on animal experimentation. The procedures are standardized at an international level. In particular the rules of ISO 10993 are the guidelines for these investigations. In the procedure of validation of a material, the choice of more than one animal species for the performing of the tests, namely a small/medium and a large size animal should be appropriate. Considering the research on biomaterials, the use of small animals can be acceptable in the early stage of testing, but for the evaluation of prototypes biofunctionality large animals should better approximate the human environment. According to ...
The Animal Protection Center of Southeastern Massachusetts is a non-profit organization that serves the animals and people of the community.. Our adoption center serves to care for and re-home homeless pets. Dogs, cats, rabbits, small mammals and birds all benefit from the attention and love provided by our dedicated staff and volunteers.. The Animal Protection Center of Southeastern Massachusetts also strives to help pet owners take the best care of their pets by providing resources such as training, low-cost vaccination and microchip clinics, and humane education outreach to children. ...
It is now more than 20 years since both Council of Europe Convention ETS123 and EU Directive 86/609?EEC were introduced, to promote the implementation of the Three Rs in animal experimentation and to provide guidance on animal housing and care. It might therefore be expected that reports of the implementation of the Three Rs in animal research papers would have increased during this period. In order to test this hypothesis, a literature survey of animal-based research was conducted. A randomly- selected sample from 16 high-profile medical journals, of original research papers arising from European institutions that featured experiments which involved either mice or primates, were identified for the years 1986 and 2006 (Total sample = 250 papers). Each paper was scored out of 10 for the incidence of reporting on the implementation of Three Rs-related factors corresponding to Replacement (justification of non-use of non-animal methods), Reduction (statistical analysis of the number of animals ...
Tomo Editorial and HSI launched Animal Experimentation: An Obstacle to Scientific Progress, a book providing an in-depth analysis of animal use in research from a scientific and historical perspective. The book is part of a growing movement among the Brazilian and international scientific community questioning the effectiveness of animals as models of human biology and disease.
Bhat, Ajaz A; Younes, Salma N; Raza, Syed Shadab; Zarif, Lubna; Nisar, Sabah; Ahmed, Ikhlak; Mir, Rashid; Kumar, Sachin; Sharawat, Surender K; Hashem, Sheema; Elfaki, Imadeldin; Kulinski, Michal; Kuttikrishnan, Shilpa; Prabhu, Kirti S; Khan, Abdul Q; Yadav, Santosh K; El-Rifai, Wael; Zargar, Mohammad A; Zayed, Hatem; Haris, Mohammad; Uddin, Shahab... more authors ... less authors ...
Al-Awar A.; Alm?si N.; Szab? R.; Takacs I.; Murlasits Z.; Sz?cs G.; T?r?k S.; P?sa A.; Varga C.; Kupai K.... more authors ... less authors ...
In 1985, the U.S. Interagency Research Animal Committee (IRAC) advised that unless the contrary is established, investigators should consider that procedures that cause pain or distress in human beings may cause pain or distress in animals(http://www.aclam.org/pub_pain_distress.html). Accordingly, the humane use of research animals requires adequate veterinary medical care during animal experimentations and includes the prevention or the alleviation of pain associated with procedural or surgical protocols (clinical pain). Guidelines on the recognition of pain are accepted by researchers but often not so easy to put into practice, especially with mice, the most frequently used laboratory animals. Why?. Mice live in constant fear of falling prey to their enemies, therefore they are prone to show as few signs of disease, suffering or weakness as possible [2-4]. Accordingly, during animal experiments, or even when a person is simply present in the room, the mouse will hide almost all signs of ...
In 1985, the U.S. Interagency Research Animal Committee (IRAC) advised that unless the contrary is established, investigators should consider that procedures that cause pain or distress in human beings may cause pain or distress in animals(http://www.aclam.org/pub_pain_distress.html). Accordingly, the humane use of research animals requires adequate veterinary medical care during animal experimentations and includes the prevention or the alleviation of pain associated with procedural or surgical protocols (clinical pain). Guidelines on the recognition of pain are accepted by researchers but often not so easy to put into practice, especially with mice, the most frequently used laboratory animals. Why?. Mice live in constant fear of falling prey to their enemies, therefore they are prone to show as few signs of disease, suffering or weakness as possible [2-4]. Accordingly, during animal experiments, or even when a person is simply present in the room, the mouse will hide almost all signs of ...
The branch of animal research in Halhale Agriculture Research Center will distribute special animal feed in the near future, disclosed Dr. Tsegai Tesfai, head of the branch. Halhale, 7 March 2011 - The branch of animal research in Halhale Agriculture Research Center will distribute special animal feed in the near future, disclosed Dr. Tsegai Tesfai, head of the branch. He told ERINA that the branch has conducted research on 550 grazing grasses that can adapt to drought in collaboration with an Australian research center and that 12 select grass have already been distributed in various parts of Gash-Barka, Anseba and Central regions for experiment purposes. Dr. Tsegai said the rest would be directly distributed to farmers after it is multiplied. Dr. Tsegai explained that producing animal feed from various cereals such as maize, sorghum and the like that can boost milk production are some of the future major work programs of the research center. ...
While it is important to provide a full explanation of the reasons why animal research and testing is important for modern medicine, it can sometimes be useful to have a handful of short pro animal research one-liners on hand. These work particularly well for Twitter - which is why each of our lines below includes…
Scientists have managed to successfully open and close the protective cover around the brain - the blood-brain barrier - in a human patient as a means for drug delivery, following work in a range of animals including mice and monkeys.
More studies need to be done, but we think theres potentially no limit on the diseases this screening disease could be applied to other than the human imagination,. http://www.diabetes.co.uk/news/2015/aug/zebrafish-embryos-used-to-identify-potential-type-1-diabetes-drugs-95530698.html. 26/08/15. Resveratrol, a chemical found in the skin of grapes (and consequently red wine) may have beneficial cardiovascular effects. However, studies in dogs show varying effects on the immune systems of dogs - increasing and decreasing it in different ways simultaneously.. Axiak-Bechtel said Seeing a decrease in neutrophil function typically means an immune system is losing the ability to kill invaders like bacteria. Combining this loss of bacteria-fighting ability with an increase in inflammatory cytokines creates a very interesting mixed message in terms of what resveratrol is doing to the immune system.. http://www.alnmag.com/news/2015/08/red-wine-compound-causes-conflicting-changes-dogs-immune-systems ...
BY KURT CUNNINGHAM , JUNE 12, 2009 7:26 AM UI researchers will have a new underground facility to house animals after the state Board of Regents approved an indoor enclosure for $11.2 million at Thursdays meeting.. Scientists hope the new facility - which will cost almost $134 million - will contribute to better research and security.. At 35,000 square feet, the underground lab will connect the Medical Education Research Facility and Carver Biomedical Research Building. It is a late addition to the Institute for Biomedical Discovery - a project the UI has already started. Officials set aside state and federal money in 2007 to be distributed over several years for the initial project. They also received private donations given specifically to the project, said UI spokesman Tom Moore. Science is important to Iowans, he said. Dr. George Weiner [the director of the Holden Comprehensive Cancer Center] says there are many research ideas that dont get funded, and a facility such this increases the ...
The new EU directive on the protection of animals used for scientific purposes (2010/63/EU) has been implemented. One of the requirements of the directive is that each breeder, supplier and user of laboratory animals sets up an Animal Welfare Body (AWB, Instantie voor Dierenwelzijn, IvD in The Netherlands). The AWB helps to ensure a responsible animal experimentation policy and is responsible for the a number of tasks: The animal-welfare body shall, as a minimum, carry out the following tasks: Advice the staff dealing with animals on matters related to the welfare of animals, in relation to their acquisition, accommodation, care and use; Advise the staff on the application of the requirement of replacement, reduction and refinement, and keep it informed of technical and scientific developments concerning the application of that requirement; Establish and review internal operational processes as regards monitoring, reporting and follow-up in relation to the welfare of animals housed or used in ...
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Learn all about the field of medical research and experimentation with insightful articles and fascinating updates in the field of medicine. From animal experimentation, clinical trials, biomedicine, and breakthroughs in medical technology, weve got you covered.
Animal models remain at that time a reference tool to predict potential pulmonary adverse effects of nanomaterials in humans. However, in a context of reduction of the number of animals used in experimentation, there is a need for reliable alternatives. In vitro models using lung cells represent relevant alternatives to assess potential nanomaterial acute toxicity by inhalation, particularly since advanced in vitro methods and models have been developed. Nevertheless, the ability of in vitro experiments to replace animal experimentation for predicting potential acute pulmonary toxicity in human still needs to be carefully assessed. The aim of the study was to evaluate the differences existing between the in vivo and the in vitro approaches for the prediction of nanomaterial toxicity and to find advanced methods to enhance in vitro predictivity. For this purpose, rats or pneumocytes in co-culture with macrophages were exposed to the same poorly soluble and poorly toxic TiO2 and CeO2 nanomaterials, by the
Because scientific inquiry involves exploration of the unknown, the outcome of experimental procedures is sometimes unpredictable. In the case of animal experimentation, this may result in situations in which animal health and/or welfare are adversely affected.. Genetically manipulated animals (GMA) provide a good example. Initially, the overall effect(s) of a particular genetic manipulation may be unknown. However, once animals are generated the resulting novel phenotypes may include immune deficiency, metabolic disorders, behavioral abnormalities or other health issues that make those animals more susceptible to disease or distress. GMA lines that exhibit abnormalities in health or behavior often require the establishment of revised husbandry and/or monitoring protocols. Humane endpoints specific for the GMA line may also need to be developed. More information on assessing the welfare of GMA can be found on the NC3Rs site.. In the case of a new GMA line it is recommended that the first ...
It is my pleasure to welcome you to join us at the Noguchi Memorial Institute for Medical Research (NMIMR), Ghanas leading biomedical research institute at the University of Ghana. The Institute has over the years embarked on a series of initiatives to upgrade its research infrastructure and human capacity to attract the worlds best scientists, technologists, postdoctoral fellows, postgraduate students, undergraduate interns, and health professionals through training and experiential learning. Our community continues to grow and we are happy to share our research, training and learning experience with you.. At the NMIMR, we conduct both laboratory and field-based research into communicable and non-communicable diseases of public health importance; led by researchers in nine departments of the institute, namely Animal Experimentation, Bacteriology, Clinical Pathology, Electron Microscopy and Histopathology, Epidemiology, Immunology, Nutrition Parasitology, and Virology. Whether you are a ...
Andy Maniotis (University of Iowa), American Journal of Pathology, 1999 Cancer! Its our Grim Reaper, todays Black Death, a dark and terrible health threat and destroyer of lives. We hear about it, read about it, and fear it more deeply than any other present disease. Ominously, projections indicate that one in every five of us will die of cancer, and 40 percent of us will have a diagnosis of cancer sometime in life. Considering that there are more than 200 different forms of human cancer alone, the hope for a magic bullet that will cure all is just pie in the sky. The disease first went political in 1971, when the Nixon administration declared the War on Cancer. We all know the war has not yet been won, even with billions poured into it every year. In fact, cancer deaths have increased steadily. This humiliating defeat is in large part due to our addiction to animal experimentation. It is an open secret in scientific circles that animal-modeled biomedical research yields results that cant ...
Animal experimentation and the models by which it is conducted are a core component of the Preclinical Translational Research Units work. Animal models are the primary mode of research responsible for translating preclinical project work into successful clinical trials, which is why they are a focus of our unit.. We work to create animal models that minimize the consumption of resources, especially time and money, without allowing for any compromise in the integrity of our data or their reproducibility. By continually striving to uphold these standards while continually striving to assess and improve our animal models we ensure that we consistently deliver optimum results and solutions.. Under the Duke Preclinical Translational Research Units expert guidance we hope to be able assist our partners in designing the model and method that allow for the creation of experiments that run correctly the first time, reducing waste and repetition.. We employ the following animal types for our animal ...
Science Institutions are concerned with their public image, which often determines their funding, so that they are often keen to be seen to promote public dialogue and engagement.. . Many government departments are interested in science education, training teachers, etc. Often they have funds for specific public projects like adult learning, animal experimentation, synthetic biology etc.,. . Many cultural and artistic groups are now including science in their agendas, since human sciences are questioning the traditional views of art, philosophy, literature, etc. So Arts centres are often keen to adopt SciCafes.. . As for schools cafes, it is clear that science education is in crisis almost everywhere in the world, so that new ideas are widely acceptable. Approaching teachers, individual schools and education authorities is a fairly easy way to start Cafes in schools - although it is more difficult to keep them free from the hierarchy within the school.. So in many ways the Cafes can build ...
First, it is interesting per se, to find common psycho-physiologic grounds between our and other animals behaviour and psyche. Second, such commonality allows us to explore new ways (treatments, drugs) for dealing with human suffering (anxieties, depressions, phobias etc.). I do not know of any other procedure or behavioural test, or physiological index, that compares anxiety and relief, which would provide 20-fold (2000%) difference in objective measurements (it is usually measured in fractions, like 35% or so). Our rats sigh approx. 25 times/hour spontaneously, less than 10/h when anxious, but more than 180/h when relieved! So, consider, if you really have experimental animals` wellbeing in mind and not just negative feeling about any animal experimentation, that far fewer animals will be required to test a new psychotropic drug or some other procedure, when measuring emotional states (using sighs instead of heart rate, blood pressure etc.) is so dramatically improved (as demonstrated by ...
St. Lukes-Roosevelt Institute for Health Sciences, New York, NY - Facility Reports and Information - Resources and Links From Stop Animal Exploitation NOW! (SAEN) - Exposing the truth to wipe out animal experimentation
University of Akron cited in the deaths of 2 voles in research lab - Media Coverage - Stop Animal Exploitation NOW! - Exposing the truth to wipe out animal experimentation
new approaches for a new millennium. (beginning narration). Education and training in the life sciences require that students learn a diversity of skills as well as the traditional knowledge base.. Graduates who enter the professions must be familiar with the technology employed in todays laboratories and clinics, and with the design and performance of experiments.. Of equal importance is the ability to communicate well with patients, and the sensitivity to appreciate complex ecological systems.. Some will also need hands-on experience of animals and animal tissue for their careers.. All students of biological science and veterinary and human medicine perform practical work to illustrate knowledge and to gain a number of these skills, practical work which for some involves dissection and animal experimentation.. But the tools and approaches used by teachers are evolving in response to developments in technology and the demands of students and society itself.. In this film, we investigate new ...
BALB/c is an albino, laboratory-bred strain of the house mouse from which a number of common substrains are derived. Now over 200 generations from New York in 1920, BALB/c mice are distributed globally, and are among the most widely used inbred strains used in animal experimentation. The founding animals of the strain were obtained by Halsey J. Bagg of Memorial Hospital, New York, from a mouse dealer in Ohio in 1913. From 1920, the progeny of the original colony were systematically inbred, sibling to sibling, for 26 generations over 15 years. During this time, the colony passed through the care of a number of scientists, including C.C. Little and E.C. MacDowell at the Carnegie Institution of Washington and H.J. Muller at the University of Texas at Austin. By 1935 the animals were in the possession of Mullers student, George Davis Snell, who moved them to The Jackson Laboratory. This stock provided the basis of all the BALB/c substrains that are now in use around the world. Snell provided some ...
Dr. Cuellos lab is interested in degenerative and regenerative processes in the CNS with particular emphasis on aging and Alzheimers disease (AD) related studies. His lab utilizes and develops transgenic animal models presenting features of the AD neuropathology. The research is of a multidisciplinary nature ranging from molecular approaches to whole animal experimentation and with a particular interest in Alzheimers Therapeutics.. ...
​The Center For Ethical Science (CFES) is a non-profit animal advocacy organization dedicated to: educating the public on the inefficacy of invasive animal experimentation; exposing how tax dollars pay for much of it and what we can do to help eliminate it; and promoting effective and humane ways of conducting scientific and cosmetic research.
The following list provides links to some of our favourite research papers and other resources that will help you learn more about animal experimentation, the solutions and why the use of animals to try and predict the human response to drugs and disease is scientifically flawed.
The Finnish Centre for Alternative Methods (FICAM) is the centre of expertise for alternative methods to animal experimentation in Finland.
The effect of nitrogen oxides on immunity was examined in animal experimentation and in clinical trials. In guinea pig, immunity was found to be lowered following 6 months exposure to 1 ppm; there...
GARDskin enables a robust and accurate way of predicting the ability of chemicals to induce sensitization, without the use of animal experimentation, skin sensitization
All advances in medicine have an underlying basis in biomedical research. Animal research is done with great care and is done with special concern for the ethical treatment of the animals. The importance of medical research lies in the fact that new knowledge in medicine and innovative development is going to take place only when medical research is done. -Michael E. DeBakey, Jr., M.D. (Legendary Heart Surgeon and Inventor ...
This recognition is now prompting some AIDS activists to argue that experiments with other species are holding back the development of safer, more-effective anti-HIV drugs. One of Britains top researchers, Prof. Robin Weiss, has expressed serious doubt that information gathered from studies of laboratory animals can help illuminate the mechanisms by which HIV sabotages the immunity of humans. Another senior AIDS doctor in Britain has described the millions of dollars spent on animal research as ...