This report presents statistics on conditions diagnosed and surgical and nonsurgical procedures performed in non-Federal short-stay hospitals. The statistics are based on data collected through the National Hospital Discharge Survey from a national s ...
Marinov, Georgi K, Wang, Jie, Handler, Dominik, Wold, Barbara J, Weng, Zhiping, Hannon, Gregory J, Aravin, Alexei A, Zamore, Phillip D, Brennecke, Julius, Toth, Katalin Fejes (March 2015) Pitfalls of Mapping High-Throughput Sequencing Data to Repetitive Sequences: Piwis Genomic Targets Still Not Identified. Developmental Cell, 32 (6). pp. 765-771. ISSN 1534-5807 ...
The evolution of cognitive neuroscience has been spurred by the development of increasingly sophisticated investigative techniques to study human cognition. In Methods in Mind, experts examine the wide variety of tools available to cognitive neuroscientists, paying particular attention to the ways in which different methods can be integrated to strengthen empirical findings and how innovative uses for established techniques can be developed. The book will be a uniquely valuable resource for the researcher seeking to expand his or her repertoire of investigative techniques.. Each chapter explores a different approach. These include transcranial magnetic stimulation, cognitive neuropsychiatry, lesion studies in nonhuman primates, computational modeling, psychophysiology, single neurons and primate behavior, grid computing, eye movements, fMRI, electroencephalography, imaging genetics, magnetoencephalography, neuropharmacology, and neuroendocrinology. As mandated, authors focus on convergence and ...
Bernstein, R. M., Morgan, S. H., Chapman, J., Bunn, C. C., Mathews, M. B., Turnerwarwick, M., Hughes, G. R. V. (1984) Anti-Jo-1 Antibody - a Marker for Myositis with Interstitial Lung-Disease. British Medical Journal, 289 (6438). pp. 151-152. ISSN 0959-8138 Bilan, D. S., Matlashov, M. E., Gorokhovatsky, A. Y., Schultz, C., Enikolopov, G. N., Belousov, V. V. (July 2013) Genetically encoded fluorescent indicator for NAD(+)/NADH ratio imaging in different cellular compartments. Febs Journal, 280 (S1). p. 615. ISSN 1742-464X Ermakova, Y. G., Bilan, D. S., Mishina, N., Markvicheva, K. N., Enikolopov, G., Belousov, V. V. (July 2013) Genetically encoded red fluorescent probe for intracellular H2O2 detection. Febs Journal, 280 (S1). pp. 606-607. ISSN 1742-464X Herbert, M. R., Russo, J. P., Yang, S., Roohi, Jasmin, Blaxill, M., Kahler, S. G., Cremer, L., Hatchwell, Eli (2006) Autism and environmental genomics. NeuroToxicology, 27 (5). pp. 671-684. ISSN 0161813X Huang, Yu-Han, Vakoc, Christopher R (July ...
Module Aims:. The aim of this module is to equip the student with a clinically-based understanding of relevant cardiovascular disorders, the risk factors and an analysis of these disorders, and the investigative techniques and therapeutic strategies used to manage such risk.. Module Outcomes:. By the end of the module students will be able to:. 1. Relate cardiovascular disease processes to clinical manifestations and their impact upon normal function.. 2. Reflect upon the role of particular investigative techniques in clinical evaluation of cardiovascular disease.. 3. Assess the role of fundamental therapeutic strategies in the treatment of cardiovascular disease.. 4. Appreciate the contemporary evidence base for cardiovascular risk and critically evaluate risk modification guidelines.. 5. Characterise an individuals risk factor profile in a clinical setting.. This module contributes to the following core dimensions:. ...
Heart failure-related hospitalizations increased between 1979 and 2004. This increase was consistent with other earlier reports of national hospitalization data (1-4,11-13); however, our report provides the most recent data. This increase was greater for hospitalizations among patients with heart failure as an additional diagnosis than among those with heart failure as the first-listed diagnosis. Moreover, among hospitalizations with any mention of heart failure, the proportion with a first-listed diagnosis of CHD and other CVD declined. However, the proportions of hospitalizations with first-listed diagnoses of respiratory or other non-CVD increased and surpassed CHD as the most common first-listed diagnosis. During the same period, in-hospital mortality declined among patients hospitalized with heart failure. This decline was greater among hospitalizations with heart failure as the first-listed diagnosis than among those with an additional diagnosis of heart failure.. The growing burden of ...
The JAK2/STAT signaling pathway mediates cytokine receptor signals that are involved in cell growth, survival and homeostasis. JAK2 is a member of the Janus kinase (JAK) family and aberrant JAK2/STAT is involved with various diseases, making the pathway a therapeutic target. The similarity between the ATP binding site of protein kinases has made development of specific inhibitors difficult. Current JAK2 inhibitors are not selective and produce unwanted side effects. It is thought that increasing selectivity of kinase inhibitors may reduce the side effects seen with current treatment options. Thus, there is a great need for a selective JAK inhibitor. In this study, we identified a JAK2 specific inhibitor. We first identified key pharmacological interactions in the JAK2 binding site by analyzing known JAK2 inhibitors. Then, we performed structure-based virtual screening and filtered compounds based on their pharmacological interactions and identified compound NSC13626 as a potential JAK2 inhibitor.
Per 10,000 population. Hospitalization for stroke (cerebrovascular disease) is defined as a first-listed diagnosis on the medical record of 430-438, as coded according to the International Classification of Diseases, 9th Revision, Clinical Modification. This includes hospitalizations for acute strokes, transient ischemic attack, and for late effects of stroke. Rates were calculated using U.S. Census Bureau 2000-based postcensal civilian population estimates.. † 95% confidence interval. In 2010, hospitalization rates per 10,000 population for stroke for males and females increased with increasing patient age. For males, the rate per 10,000 ranged from 14.7 for those aged ,65 years to 285.7 for those aged ≥85 years. For females, the rate ranged from 11.6 per 10,000 population for those aged ,65 years to 277.4 for those aged ≥85 years. Within each age group, the rates for males and females were similar. Sources: National Hospital Discharge Survey data (2010). Available at ...
MSC Solutions for Medical Device Industry Simulation Methods for Reducing Risk and Accelerating Innovation MSC Software Medical Device Industry Delivering Certainty by Helping You Simulate Real World Behaviors
This report presents statistics on the National Bowel Cancer Screening Program (NBCSP) using key performance indicators. Of those who were invited to participate in the NBCSP between 1 January 2014...
EFSA has performed a public consultation on the draft Guidance Document on the risk assessment of Plant Protection Products on bees (Apis mellifera, Bombus spp. and solitary bees). This report presents statistics on the comments received and lists all com .... ...
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Manufacturers of the Medical Devices are required to obtain manufacturing license under the provisions of Drugs and Cosmetic (D&C) Act & Rules which is notified by Directorate General of Health Services, Ministry of Health & Family Welfare.
Mr. Rajiv Nath, Forum Coordinator of Association of Indian Medical Device Industry (AiMeD) on behalf of the Indian Medical Device Industry applauded Niti Aayog for conducting a meeting with various stakeholders today and presenting the proposed Medical Devices Bill, as a great visionary & well thought out Road Map with many innovative elements and which is in line with the requirements for the advancement & betterment of Indian Medical Device industry and stated Health Policy of the country. Mr. Rajiv Nath during the meeting again emphasized the need for a Separate Act for Medical Devices, Separate Regulatory framework away from Drugs, Separate Regulatory Authority under Ministry of Health or a Revamped strengthen CDSCO but headed by a Medical Professional or Scientist familiar with Medical Devices. "We are encouraged and very hopeful that the Medical Devices Bill proposed by NITI Aayog today is seemingly an answer to this long outstanding wish list and will be very much beneficial for Growth of ...
Find Medical Devices market research reports and Medical Devices industry market forecast covering Healthcare industry trends, market segmentation, market share, opportunities, market growth and market projection by MicroMarketMonitor.com
Find Medical Devices market research reports and Medical Devices industry market forecast covering Healthcare industry trends, market segmentation, market share, opportunities, market growth and market projection by MicroMarketMonitor.com
To the Editor: In their recent article, Lee et al1 mention that their index, which is derived and validated by a superb methodology, can identify which stable patients undergoing nonurgent major noncardiac surgery are at a higher risk for complications. In fact, the assessment of preoperative cardiac risk is complicated by many interposed problems. In the surgical decision-making process, it is precisely the assessment of all general risks (and not only cardiac risk) that could be of clinical interest, inasmuch as general risk factors can indeed be the indirect cause of postoperative cardiac complications and general complications can be the consequence of overlooked cardiac risk factors. Furthermore, the authors do not consider data from emergency surgery patients, although emergency is a widely reported independent predictor of operative risk.. As general surgeons working next door to busy cardiology and cardiac surgery services, we developed expertise with elective and emergency noncardiac ...
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Market Publishers Ltd informs that new GlobalDatas Medical Devices Industry Reports have been added to its catalogue:. Orthobiologics - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017.. The global orthobiologics market was valued at $4.8 billion in 2010, and is forecast to grow at a compound annual growth rate (CAGR) of 6.8% to reach $7.6 billion in 2017. The market is expected to be driven by a rapid increase in the elderly population, an increase in the prevalence of arthritis, technological innovations, the increasing number of spinal fusion surgeries and the increase in the trend of medical tourism.. Arthroscopy Devices - Global Pipeline Analysis, Opportunity Assessment and Market Forecast to 2017.. The global arthroscopy devices market is forecast to reach $3.9 billion by 2017, with a compound annual growth rate (CAGR) of 5% from 2010-2017. Arthroscopy devices are used to diagnose and treat joint defects, and an increasing number of surgeons are using this ...
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Johnson & Johnson hit with FDA warning letter | MassDevice - Medical Device Industry News. Johnson & Johnson hit with FDA warning letter January 12, 2012 by MassDevice staff More regulatory woes as Johnson & Johnson hit with a warning letter from the FDA regarding its insulin pumps. Animas Corp.s OneTouch Ping insulin pump The…
Part of the issue is that VCs have been having a much tougher time raising money since the 2008 financial crisis than other asset classes in general (riskier investment class and not all funds performed well). Add to that, the challenges of the medical device industry, which is a pretty specialized domain vs. pharma, with fewer exit options for companies (relatively speaking) since the US IPO market has not been available for medtech, vs. being very hot for biotech in 2013. Additionally, remaining VCs have been tending to invest in later stage companies, hoping that this will mean greater certainty of a return (though possibly a lower ROI multiple); we have not embraced this approach for our fund, however - we still believe in the traditional VC model: "buy low, sell high". As a result, VCs are investing money in the sector, but they tend to be reinvesting in their existing portfolio rather than in new companies, hence the challenge of raising money for Series A deals. One positive factor has ...
Buy We Dont Build Cars; The Art of Sustained Competitive Improvement in the Drug and Medical Device Industries by William Botha (Paperback) online at Lulu. Visit the Lulu Marketplace for product details, ratings, and reviews.
Visual disturbances may be caused by diseases of the optic disc, optic nerve, optic chiasm, optic tract, lateral geniculate nucleus, optic radiations, and occipital lobe of the brain, as well as other brain areas involved in complex visual processing.Diagnosis of disturbances of the visual pathways requires both knowledge of their anatomy and physiology, and the ability to carry out a thorough neuro-ophthalmological examination which should enable (1) documentation of the character and extent of the visual disturbance, and (2) topographic localization of the lesion, so that the relevant investigative techniques, such as radiological imaging, can be appropriately requested....
In recent years, US-guided percutaneous biopsy has emerged as one of the main investigative techniques to obtain histopathological specimens from chest lesions (7). Increasingly, it is becoming the first-choice investigation in chest lesions because of its advantages of procedural simplicity, safety and effectiveness, without the risk of exposure to ionizing radiation (5,6) Despite its high success rate and fewer complications, conventional US has certain limitations in the preoperative evaluation of chest lesions and the design of the puncture path (7). For example, although conventional 2D US can recognize liquefaction within lesions, it may only poorly identify necrotic and un-liquified tissues (7). In addition, although CDFI can broadly observe lesion vascularity, it has low sensitivity and the results of the observation are easily influenced by numerous factors, including the angle between the sound wave and the blood vessel, false negative readings by slow blood flow and noise interference ...
AD and frontotemporal dementia (FTD) are neurodegenerative diseases typified by the insidious onset and gradual progression of cognitive impairment. In both instances, the diagnosis can be confirmed only by histologic examination of brain tissue and observation of the characteristic neuropathologic changes that are associated with each disease. Although current in vivo investigative techniques are unable to visualize directly these pathologic changes, it is possible to detect by neuroimaging the cerebral atrophy that occurs as a consequence of the pathologic processes, and this has led to the utilization of measures of brain atrophy as biomarkers in the evaluation of dementia.. MRI has emerged as a useful neuroimaging tool in the investigation of AD on account of its relative safety and tolerability and its ability to delineate individual structures within the brain. The reduction in total brain volume that occurs in AD is difficult to estimate with confidence on a single scan because of the ...
The Organized Crime Drug Enforcement Task Force (OCDETF) is responsible for the identification, investigation and prosecution of major drug trafficking organizations. To accomplish this mission, the OCDETF employs case acceptance criteria that are likely to result in the identification of links to major drug trafficking organizations. Once the organizations are identified, the Task Force uses the most sophisticated investigative techniques available such as pen registers, cell phone tracking and global positioning systems, as well as the extensive use of the grand jury, search warrants and wire interceptions. Money laundering charges and asset forfeiture are widely used by OCDETF ...
Looking for high-risk surgery? Find out information about high-risk surgery. branch of medicine medicine, the science and art of treating and preventing disease. History of Medicine Ancient Times Prehistoric skulls found in Europe... Explanation of high-risk surgery
RESULTS: An estimated 34.7 million discharges from nonfederal short-stay hospitals occurred in 2005. Discharges used 165.9 million days of care and had an average length of stay of 4.8 days. Persons 65 years and over accounted for 38 percent of the hospital discharges and 44 percent of the days of care. The proportion of discharges whose status was described as routine discharge or discharged to the patients home declined with age, from 91 percent for inpatients under 45 years of age to 41 percent for those 85 years and over. Hospitalization for malignant neoplasms decreased from 1990-2005. The hospitalization rate for asthma was the highest for children under 15 years of age and those 65 years of age and over. The rate was lowest for those 15-44 years of age. Thirty-eight percent of hospital discharges had no procedures performed, whereas 12 percent had four or more procedures performed. An episiotomy was performed during a majority of vaginal deliveries in 1980 (64 percent), but by 2005, it ...
These industry measurement tools provide assessment of the strengths, threats, weaknesses and the present opportunities. It also elaborates the comprehensive industrial insights about the global Pressure Measurement Device market. Besides this, the research report examines the ongoing political scenarios that are anticipated to illustrate the pricing, import/ export in the worldwide Pressure Measurement Device market. Furthermore, the study report also explains the significant opportunities available in the overall global Pressure Measurement Device industry.. The research document on the global Pressure Measurement Device market includes a deep segmentation of the respective industry. The world Pressure Measurement Device market is segregated on the basis of application, major players, regions and product types. Each segment contains an in-depth explanation of the parameters that are likely to enhance and hamper the global Pressure Measurement Device market.. Major Industry Players Involved in ...
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Obstetric Analgesia and Anesthesia: A Manual for Physicians, Nurses and Other Health Personnel, Prepared for the World Federation of Societies of
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180 days after DES implantation. Thus, these findings may help inform clinical decision making regarding the timing of major elective noncardiac surgery after recent PCI. However, the decision of timing for elective surgery should be individualized, balancing the well-understood risks of restenosis with less certain risks of stent thrombosis, as well as patient anatomy, perioperative bleeding risks, and risks of delaying surgical procedures. Although surgery >180 days after DES may be reasonable in some non-ACS simple lesions with good acute results, data from the current study do not have sufficient size and scope to change current guidelines and recommend earlier surgery after DES, when there remain concerns regarding the residual risk of stent thrombosis within the first year.. ...
A medical devices news site with hand-picked news of interest and relevance to the international medical device user, specifier and industry watcher
Our findings suggest that elective noncardiac surgery can be performed reasonably safely in carefully selected patients once at least 6 months have elapsed since drug-eluting stent implantation. There may also be an optimal time window for performing surgery within the year after bare-metal stent implantation, namely from 46 to 180 days after PCI. Although the presence of this optimal window is not certain, especially because its associated adjusted odds ratio is imprecise, this window is biologically plausible. It represents the period when re-endothelialization is largely complete after bare-metal stent implantation30 but when in-stent restenosis has yet to completely manifest itself.31 Conversely, once ,1 year has elapsed since either bare-metal or drug-eluting stent implantation, physicians can be reassured that the associated perioperative cardiac risk has reached a plateau, with risks similar to that of individuals with remote histories of previous PCI (ie, 2 to 10 years before ...
Team Elysium Inc. Releases New Medical Device for Measuring Posture. Suggests the New Paradigm of Healthcare with the AI Smart Medical Device - PR12754079
Sample: All hospitals with 1,000 beds or more in the original universe of short-stay hospitals were selected with certainty in the sample. All hospitals with fewer than 1,000 beds were stratified, the primary stratum depending on size and geographic region. Within each of these 24 primary strata, the allocation of the hospitals was made through a controlled selection technique so that hospitals in the sample would be properly distributed with regard to type of ownership and geographic division. Sample hospitals were drawn with probabilities ranging from certainty for the largest hospitals to 1 in 40 for the smallest hospitals. Of the 535 hospitals in the sample, 413 were in scope and agreed to participate. The within-hospital sampling ratio for selecting sample discharges varied inversely with the probability of selection of the hospital. The smallest sampling fraction of discharged patients was taken in the largest hospitals, and the largest fraction was taken in the smallest hospitals. In ...
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Manufacturers can start selling implanted medical devices before they have been tested for safety, so its a good idea to consider alternatives to getting one, experts advise.
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AGAWAM, Mass., Oct. 24, 2012/ PRNewswire/-- A new white paper is available to assist medical device manufacturers with understanding recent changes to the U.S. Food and Drug Administrations thinking regarding endotoxin testing.
However, average total days for the review of 510(k)s has been increasing since 2005, and has been increasing for pre-market approval applications since 2004, with early indicators of longer review times, such as the average number of cycles to review a 510(k), starting to increase since 2002. The FDA recognises that, if the US is to maintain its leadership role in this area, it must continue to streamline and modernise its processes and procedures to make device approval not just scientifically rigorous, but clear, consistent and predictable without compromising safety.. To best serve patients, the medical device industry and the FDA must have the flexibility to be innovative and entrepreneurial. First, the Center for Devices and Radiological Health (CDRH) must continue making critical improvements to its device programme. Second, the medical device industry and CDRH must work together to ensure that the centre receives high-quality submissions, which contain the information needed to make ...
Speeding up the delivery of innovative medical devices and instrumentation The medical device sector is characterised by increasing competition and accelerating change, from new companies entering the marketplace to the on-going technology revolution. Medical device organisations must be more innovative than their competitors, and ensure innovations happen quickly and efficiently.. PA Consulting Group works with medical device clients to speed the development of innovative products. Our technology centre has the laboratory, CAD/CAM, clean room and build facilities needed to conceive technology, to create working prototypes rapidly and to deliver full product development. ...
The convergence of information technology with medical devices is transforming the landscape of patient care. Get here all market insights of Medical Devices.
Capital Regional Medical Center First in U.S. to Use New Medical Device - For a 79-year-old Perry woman, medical expertise, technology, and timing came together ...
Manufacturing options available to companies making medical devices are changing rapidly," says Delcams PartMaker Inc. Division President Hanan Fishman. "The machine tool, cutting tool and CNC programming techniques available in the market today to make medical devices has changed immensely in the past 24 months. The idea of this webinar series is explain what these changes are and how firms that are either making medical devices currently or are considering doing so need to apply the latest in advanced manufacturing to manufacture medical devices productively and profitably given the dynamics of their business ...