The halophilic bacterium Chromohalobacter salexigens is a natural producer of ectoines, compatible solutes with current and potential biotechnological applications. As production of ectoines is an osmoregulated process that draws away TCA intermediates, bacterial metabolism needs to be adapted to cope with salinity changes. To explore and use C. salexigens as cell factory for ectoine(s) production, a comprehensive knowledge at the systems level of its metabolism is essential. For this purpose, the construction of a robust and high-quality genome-based metabolic model of C. salexigens was approached. We generated and validated a high quality genome-based C. salexigens metabolic model (iFP764). This comprised an exhaustive reconstruction process based on experimental information, analysis of genome sequence, manual re-annotation of metabolic genes, and in-depth refinement. The model included three compartments (periplasmic, cytoplasmic and external medium), and two salinity-specific biomass compositions,
Save 40% Lindberg - Spirulina 500 mg Organic 250 Tablets 100% Organic Spirulina 500 mg Ultimate Organics® Green SuperFood USDA Organic Pesticide and Herbicide Free Double Verified Gluten Free Our 100% Organic Spirulina is a certified organic whole food concentrate, providing a naturally rich source of vitamins, trace minerals, mixed carotenoids, antioxidants, and essential fatty acids. Spirulina provides a vegetarian source of complete protein. Spirulina Platensis contains an exceptionally high amount of C-phycocyanin, a type of algae renowned for its health benefits. Our tablets are 100% organic without herbicides, pesticides, fertilizes or preservatives and tests negative for BMAA. BMAA (beta-N-methylamino-L-alanine) is a toxin sometimes associated with spirulina. Our Ultimate Organics products do not contain conventional pesticides, synthetic fertilizers, growth hormones, genetic modification or antibiotics. We source only natural, organic raw materials that promote the use of renewable resources
The decline in SVC indicated that the drought treatment imposed severe water stress on plants. SVC in a 20-cm soil depth declined to ≈2% after 14 d of drought treatment. Our results demonstrate that GABA- (50 mm) treated perennial ryegrass maintained significantly higher RWC under drought stress than non-treated plants. RWC in leaves is a measure of internal water status during drought stress (Matin et al., 1989). The results suggest that GABA-treated perennial ryegrass plants were better able to maintain water under drought stress. The function of GABA as a compatible osmolyte under osmotic stress has been proposed by Shelp et al. (1999). Osmolyte accumulation in plant cells results in maintenance of cell turgor pressure and also protects cell membranes, protein, and metabolic machinery from cell dehydration (Hare et al., 1998; Ingram and Bartels, 1996; Rathinasabapathi, 2000). Two recent studies demonstrated that GABA was differentially accumulated in hybrid bermudagrass (Cynodon dactylon × ...
Chromohalobacter salexigens ATCC ® BAA-138D-5™ Designation: Genomic DNA from Chromohalobacter salexigens strain DSM 3043 TypeStrain=True Application:
It has been firmly established that organic osmolytes (compatible solutes) of halophilic Bacteria and Archaea have positive effects on conformation and activity of proteins, and may therefore improve their functional production. In particular, the amino acid derivative ectoine is known for its conformational stabilization, aggregation suppression, and radical protection properties. The natural producer and industrial production strain Halomonas elongata accumulates ectoine in the cytoplasm, and as a result offers a unique stabilizing environment for recombinant proteins. For the construction of broad hoast range vector systems with fluorescent reporter proteins, we chose the salt-inducible promoter region of the ectoine gene cluster (promA). A closer inspection of the genetic background revealed that its combination of sigma 38 (σ38) and sigma 70 (σ70) promoters was followed by a weak ribosomal binding site (RBS). This inspired a systematic approach for the construction of a promA-based vector series
Cyanobacteria produce a range of secondary metabolites, one being the neurotoxic non-protein amino acid β-N-methylamino-L-alanine (BMAA), proposed to be a causative agent of human neurodegeneration. As for most cyanotoxins, the function of BMAA in cyanobacteria is unknown. Here, we examined the effects of BMAA on the physiology of the filamentous nitrogen-fixing cyanobacterium Nostoc sp. PCC 7120. Our data show that exogenously applied BMAA rapidly inhibits nitrogenase activity (acetylene reduction assay), even at micromolar concentrations, and that the inhibition was considerably more severe than that induced by combined nitrogen sources and most other amino acids. BMAA also caused growth arrest and massive cellular glycogen accumulation, as observed by electron microscopy. With nitrogen fixation being a process highly sensitive to oxygen species we propose that the BMAA effects found here may be related to the production of reactive oxygen species, as reported for other organisms.
Neurolathyrism is a neurological condition seen among people who eat the seeds of Lathyrus sativus as a principal source of food energy for 2 months or more. It is characterised by severe muscular rigidity and irreversible spastic paralysis of the lower limbs, spinal hyperreflexia, and structural changes of the skeleton and connective tissue (18-19). Once prevalent throughout Europe, N. Africa, the Middle East and parts of the Far East, the disease is presently restricted to India, Bangladesh and Ethiopia (20). The biochemical mechanism involves beta-N-Oxalyl amino-L-alanine (L-BOAA); a synonym is beta-N-oxalyl-alpha,beta-diaminopropionic acid (beta-ODAP). This is a naturally occurring non-protein amino acid present in Blue vetch. Ingestion of L-BOAA in a staple diet results in a progressive neurodegenerative condition, a form of motor neuron disease that affects the upper motor neurons and anterior horn cells of the lumbar spinal cord. L-BOAA is an excitatory acid and acts as an agonist at the ...
General Information: Halomonas elongata DSM 2581 was isolated from a solar salt facility and is halotolerant up to a concentration of 35%. Halomonas elongata is a halophilic bacterium which uses ectoine as its major compatible solute. This organism can both, synthesize and degrade ectoine and is used as industrial ectoine producer. ...
Citrulline is a non-protein amino acid, isolated from watermelon, involved in the urea cycle and an arginine precursor. Participants will take 10g/d of citrulline or placebo (isocaloric).. High intensity interval training (HIIT) is a high intensity aerobic training (30 sec at 85% and up of HRmax + 1min30 at 65-70% of HRmax). they HIIT duration is 30 min/session. HIIT is recognized as beneficial to improve health in human such as Vo2max, body fat or .. Then intervention will be follow during 12 consecutive weeks.. ...
Salinity-alkalinity stress is one of the major abiotic stresses affecting plant growth and development. γ-Aminobutyrate (GABA) is a non-protein amino acid that functions in stress tolerance. However, the interactions between cellular redox signaling and chlorophyll (Chl) metabolism involved in GABA-induced salinity-alkalinity stress tolerance in plants remains largely unknown. Here, we investigated the role of GABA in perceiving and regulating chlorophyll biosynthesis and oxidative stress induced by salinity-alkalinity stress in muskmelon leaves. We also evaluated the effects of hydrogen peroxide (H2O2), glutathione (GSH), and ascorbate (AsA) on GABA-induced salinity-alkalinity stress tolerance. Salinity-alkalinity stress increased malondialdehyde (MDA) content, relative electrical conductivity (REC), and the activities of superoxide dismutase (SOD), ascorbate peroxidase (APX) and dehydroascorbate reductase (DHAR). Salinity-alkalinity stress decreased shoot dry and fresh weight and leaf area, reduced
δ-Aminolevulinic acid (also dALA, δ-ALA, 5ALA or 5-aminolevulinic acid), an endogenous non-protein amino acid, is the first compound in the porphyrin synthesis pathway, the pathway that leads to heme in mammals and chlorophyll in plants. 5ALA is used in photo dynamic detection and photo dynamic surgery of cancer. Being a precursor of photosensitizer, 5ALA is also used as an agent for photodynamic therapy. Photodynamic detection is the use of photosensitive drugs with a light source of the right wavelength for the detection of cancer, using fluorescence of the drug. 5ALA, or derivatives thereof, can be used to visualize bladder cancer by fluorescence imaging. It elicits synthesis and accumulation of fluorescent porphyrins (protoporphyrin IX) in epithelia and neoplastic tissues, among them malignant gliomas. It is used to visualise tumorous tissue in neurosurgical procedures. Studies since 2006 have shown that the intraoperative use of this guiding method may reduce the tumour residual volume ...
L-ornithine is a non-essential, non-protein amino acid. Although L-ornithine is contained in various foods, the amount is usually small. Recently, studies have shown that orally administered L-ornithine reduced the stress response in animals. From these findings, we speculated that L-ornithine may play a role in the relieve of stress and improve sleep and fatigue symptoms in humans. Through a randomised, double-blind, placebo-controlled clinical study, we asked if L-ornithine could be beneficial to stress and sleep in healthy workers. Fifty-two apparently healthy Japanese adults who had previously felt slight stress as well as fatigue were recruited to be study participants and were randomly divided into either the L-ornithine (400 mg/day) or placebo group. They orally consumed the respective test substance every day for 8 weeks. Serum was collected for the assessment of cortisol and dehydroepiandrosterone-sulphate (DHEA-S). Perceived mood and quality of sleep were measured by the Profile of Mood States
In the Guzzoni V. et al experiment, placebo or nandrolone rats were given to rats, some animals were trained, while others were not. Nandrolone was used at a dose of 5 mg / kg body weight, 2x a week. The amount of nitric oxide formed and reactive oxygen species were evaluated using DAF-2 methods and hydroethidine fluorescence techniques. Results Conclusions: high doses of Nandrolone lower the bioavailability of nitric oxide and may induce endothelial dysfunction and morphological changes in the arteries. It is not known whether such changes occur in humans, but it can be expected - for now we are waiting for further research in this matter. __. You can read also: L-Theanine - a non-protein amino acid with interesting properties. ...
Microorganisms are known to counteract salt stress through salt influx or by the accumulation of osmoprotectants (also called compatible solutes). Understanding the pathways that synthesize and/or breakdown these osmoprotectants is of interest to studies of crops halotolerance and to biotechnology applications that use microbes as cell factories for production of biomass or commercial chemicals. To facilitate the exploration of osmoprotectants, we have developed the first online resource, Dragon Explorer of Osmoprotection associated Pathways (DEOP) that gathers and presents curated information about osmoprotectants, complemented by information about reactions and pathways that use or affect them. A combined total of 141 compounds were confirmed osmoprotectants, which were matched to 1883 reactions and 834 pathways. DEOP can also be used to map genes or microbial genomes to potential osmoprotection-associated pathways, and thus link genes and genomes to other associated osmoprotection ...
In several TRAP-T systems, fused Q-M-type proteins instead of two separate Q- and M-type proteins are found, while in others, Q-P-type fusion proteins are found. The operon encoding the Synechocystis system includes a protein homologous to the glutamine binding protein, and biochemical evidence has suggested that a glutamate transporter from Rhodobacter sphaeroides is a periplasmic binding protein-dependent, pmf-dependent secondary carrier (Jacobs et al., 1996). Homologous systems in Halomonas elongata and Rhodobacter spheroides take up ectoine/hydroxyectoine and taurine, respectively (Bruggemann et al., 2004; Grammann et al., 2002). The DctP dicarboxylate receptor is homologous to both the YiaO monocarboxylate receptor and the TeaA ectoine receptor. Thus, the TRAP-T family of permeases may be involved in the uptake of widely divergent compounds, mostly carboxylate derivatives (Kelly and Thomas, 2001; Thomas et al., 2006; Mulligan et al., 2007). The crystal structure of SiaP (the receptor for ...
Cell wall and phospholipid composition and their contribution to the salt tolerance of Halomonas elongata.: The salt-tolerant bacterium Halomonas elongata makes
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class=publication>Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href=http://www.nrbook.com/b/bookcpdf.php>Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
We present a model of osmoadaptation in S.cerevisiae based on existing experimental and theoretical work. In order to investigate the impact of osmoadaptation on glycolysis, this model focuses on the interactions between glycolysis and osmoadaptation, namely the production of glycerol and its influence on flux towards pyruvate. Evaluation of this model shows that, depending on initial relations between glycerol and pyruvate production, the increased glycerol production can have a substantial negative effect on the pyruvate production rate. Existing experimental data and a detailed analysis of the model lead to the suggestion of an interaction between activated Hog1 and activators of glycolysis such as Pfk26.
Nesterenkonia halobia strain DSM 20541 di- and tricarboxylate transporter, diaminobutyric acid acetyltransferase (ectA), diaminobutyric acid aminotransferase (ectB), and ectoine synthase (ectC) genes, complete ...
Nesterenkonia halobia strain DSM 20541 di- and tricarboxylate transporter, diaminobutyric acid acetyltransferase (ectA), diaminobutyric acid aminotransferase (ectB), and ectoine synthase (ectC) genes, complete ...
Strand breaks and conformational changes of DNA have consequences for the physiological role of DNA. The natural protecting molecule ectoine is beneficial to entire bacterial cells and biomolecules such as proteins by mitigating detrimental effects of environmental stresses. It was postulated that ectoine-like molecules bind to negatively charged spheres that mimic DNA surfaces. We investigated the effect of ectoine on DNA and whether ectoine is able to protect DNA from damages caused by ultraviolet radiation (UV-A). In order to determine different isoforms of DNA, agarose gel electrophoresis and atomic force microscopy experiments were carried out with plasmid pUC19 DNA. Our quantitative results revealed that a prolonged incubation of DNA with ectoine leads to an increase in transitions from supercoiled (undamaged) to open circular (single-strand break) conformation at pH 6.6. The effect is pH dependent and no significant changes were observed at physiological pH of 7.5. After UV-A irradiation ...
Neurodegenerative diseases are influenced by environmental factors such as exposure to toxins including the cyanotoxin β-N-methylamino-l-alanine (BMAA) that can bioaccumulate in common food sources such as fish, mussels and crabs. Accurate and precise analytical methods are needed to detect and quantify BMAA
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ECTC is armed with a great deal of knowledge, experience and expertise through its diverse membership, well positioning ECTC to educate engineers, contractors and regulatory agencies on effective erosion and sediment control practices and promote the proper use of hydraulic erosion control products, rolled erosion control products and sediment retention fiber rolls in combating the cumulative and detrimental effects of erosion on our environment.. ...
These photos are available for educational, non-commercial purposes. To download the photo, right-click your mouse over the picture or click on the hyperlink below the photo. The ECTC logo must remain on the photo and ECTC must be credited when the photo is used.. ...
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germinate.01: GERMINATE-V NOTES: Frame by Jena based on ECTB2, VNcls entity_specific_cos-45.5, sprout. Member of VNcls . entity_specific_cos-45.5, entity_specific_modes_being-47.2. (from germinate.01-v) GERMINATION-N NOTES: Corresponds with germinate.01. Framed by anwen april 2011 (from germination.01-n) ...
In accordance with the invention, nanoscale connectors particularly useful for connecting microscale devices comprise free-standing nanoscale conductors. The nanoscale conductors are conveniently fabricated in sets of controlled, preferably equal length by providing a removable substrate, growing conductive nanotubes or nanowires on the substrate, equalizing the length of the nanoscale conductors, and removing the substrate. Preferably the removable substrate is soluble, leaving a collection of free standing nanoscale connectors in suspension or solution.
Planchestainer, Matteo and Contente, Martina Letizia and Cassidy, Jennifer and Molinari, Francesco and Tamborini, Lucia and Paradisi, Francesca (2017) Continuous flow biocatalysis: production and in-line purification of amines by immobilised transaminase from Halomonas elongata. Green Chemistry, 19 . pp. 372-375. ISSN 1463-9262 Contente, Martina Letizia and Planchestainer, Matteo and Molinari, Francesco and Paradisi, Francesca (2016) Stereoelectronic effects in the reaction of aromatic substrates catalysed by Halomonas elongata transaminase and its mutants. Organic and Biomolecular Chemistry, 14 . pp. 9306-9311. ISSN 1477-0539 ...
CLINTON, NY -Indium Corporations Dr. Ning-Cheng Lee, vice president of technology, will teach a professional development course at the Electronic Components and Technology Conference (ECTC) May 27-30 in Lake Buena Vista, Florida. Lees course, Lead-Free Solder Joint Reliability - Materials Consideration, will cover materials considerations required for achieving high-reliability lead-free solder joints. This course will provide a greater understanding of how various factors contribute to the failure modes, and how to select proper alloys and surface finishes for achieving high-reliability. For more information or to register, visit www.ectc.net. Dr. Lee has extensive experience in the development of solder pastes, fluxes, high-temperature polymers, microelectronics encapsulants, underfills, and adhesives for electronics assembly. His current research interests include advanced materials for interconnects and packaging for electronics and optoelectronics applications, with emphasis on both ...
Microorganisms accumulate molar concentrations of compatible solutes like ectoine to prevent proteins from denaturation. Direct structural or spectroscopic information on the mechanism and about the hydration shell around ectoine are scarce. We combined surface plasmon resonance (SPR), confocal Raman spectroscopy, molecular dynamics simulations, and density functional theory (DFT) calculations to study the local hydration shell around ectoine and its influence on the binding of a gene-S-protein (G5P) to a single-stranded DNA (dT(25)). Due to the very high hygroscopicity of ectoine, it was possible to analyze the highly stable hydration shell by confocal Raman spectroscopy. Corresponding molecular dynamics simulation results revealed a significant change of the water dielectric constant in the presence of a high molar ectoine concentration as compared to pure water. The SPR data showed that the amount of protein bound to DNA decreases in the presence of ectoine, and hence, the protein-DNA ...
We have a limited number of places left on the next ENOVA Training School on Immunoactive carbohydrates and adjuvants: antibacterial vaccines from research to clinical trials in Sienna which is running from the 2nd to 4th April. The deadline for applications has been extended to March 8th.. The Training School is suitable for Ph.D. students and researchers who have a basic knowledge of analytical and organic chemistry and would like to increase their knowledge of vaccine development specifically in the area carbohydrate-based vaccines. https://www.enova-adjuvant.eu/training/. ...
The four last steps of biotin biosynthesis, starting from pimeloyl-CoA, are conserved among all the biotin-producing microorganisms. Two enzymes of this pathway, the 8-amino-7-oxononanoate synthase (AONS) and the 7,8-diaminopelargonic acid aminotransferase (DAPA AT) are dependent on pyridoxal-5′-phosphate (PLP). This review summarizes our current understanding of the structure, reaction mechanism ...
General Information: Chromohalobacter salexigens DSM 3043 was first isolated from a solar salt facility on Bonaire Island, Netherlands Antilles. A moderate halophile which can grow on a variety of salts. This bacterium is a moderate halophile, yet does not require high concentrations of sodium chloride. The salt requirements of this organism can be met by ions of other salts, such as potassium, rubidium, ammonium, bromide. Several plasmids have been isolated from this organism. Plasmid pMH1 contains genes for resistance to kanamycin, neomycin, and tetracycline. A smaller plasmid, pHE1, which does not code for antibiotic resistance genes, has also been isolated. ...
In this study, two populations of leguminous plants Lathyrus sativus were grown in four soils that were collected from sites differently contaminated by heavy metals. Evaluations included basic soil properties, concentrations of major nutrients and four metals (copper, zinc, lead and cadmium) in these soils. Investigation of Lathyrus sativus response to contamination showed that the increase of he ...
In most computer games as in life, the outcome of a match is uncertain due to several reasons: the characters or assets appear in different initial positions or the response of the player, even if programmed, is not deterministic; different matches will yield different scores. That is a problem when optimizing a game-playing engine: its fitness will be noisy, and if we use an evolutionary algorithm it will have to deal with it. This is not straightforward since there is an inherent uncertainty in the true value of the fitness of an individual, or rather whether one chromosome is better than another, thus making it preferable for selection. Several methods based on implicit or explicit average or changes in the selection of individuals for the next generation have been proposed in the past, but they involve a substantial redesign of the algorithm and the software used to solve the problem. In this paper we propose new methods based on incremental computation (memory-based) or fitness average or, ...
An amino acid that produces tranquilizing effects in the brain, theanine found in green tea, has a significant clinical results for naturally calming as it promotes alpha brain waves, putting you in a state of relaxation without causing drowsiness, according to the study of L-theanine: properties, synthesis and isolation from tea Vuong QV, Bowyer MC, Roach PD., posted in Pubmed (http://www.ncbi.nlm.nih.gov/pubmed/21735448), researchers wrote that Theanine is a non-protein amino acid that occurs naturally in the tea plant (Camellia sinensis) and contributes to the favourable taste of tea. It is also associated with effects such as the enhancement of relaxation and the improvement of concentration and learning ability. . It also increases the dopamine levels in the brain, leading to a well-being feeling, according to the study of The neuropharmacology of L-theanine(N-ethyl-L-glutamine): a possible neuroprotective and cognitive enhancing agent by Nathan PJ, Lu K, Gray M, Oliver C., posted in ...
Catalyses the reaction only in the opposite direction. Involved in taurine degradation. The bacterium Chromohalobacter salexigens strain DSM 3043 possesses two enzymes th
TY - JOUR. T1 - Beta-methylamino-alanine (BMAA) injures hippocampal neurons in vivo. AU - Buenz, Eric J.. AU - Howe, Charles L.. PY - 2007/5/1. Y1 - 2007/5/1. N2 - The unusually high incidence of amyotrophic lateral sclerosis/Parkinson-dementia complex (ALS/PDC) among the Chamorro people of Guam has fueled an intense search for the etiologic agent responsible for this neurodegenerative disease. Recently, a biomagnification hypothesis was proposed to account for the role of dietary consumption of β-methylamino-alanine (BMAA) in patients with ALS/PDC. However, this hypothesis is hotly debated and a direct association between BMAA and neuronal injury in vivo has been lacking. We provide evidence that introduction of BMAA into the CNS of mice leads to sporadic death of hippocampal neurons, supporting a direct causal link between BMAA and neuronal injury.. AB - The unusually high incidence of amyotrophic lateral sclerosis/Parkinson-dementia complex (ALS/PDC) among the Chamorro people of Guam has ...
An adoption of appropriate technology can lead the company to greater business competency, improve its business performance, and ensure it retains its competitive advantages. Despite this awareness, many SME in the developing countries in the Middle East have yet to fully embrace this adoption of ecommerce in the running of their business. The problem in this research is to identify and bring together in one framework the appropriate issues, variables, components and concepts that need to be addressed to encourage, motivate and enable SME‟s in Middle Eastern countries to adopt electronic commerce technology in the running of their businesses. The aim of this study is to develop a comprehensive research framework called Electronic Commerce Technology Acceptance (ECTA) framework, which is utilised for discovering the factors affecting the adoption of e-commerce innovation and to apply this framework for empirically testing the adoption of e-commerce application by SMEs in Middle Eastern Countries. This
In 1944 Guam was recaptured and fortified by US forces. Decades later soldiers that were stationed at Guam developed ALS-PDC (amyotrophic lateral sclerosis-parkinsonism/dementia complex) 50-100 times the incidence of ALS. Also Guams natives, the Chamorro, are plagued by severe neurodegenerative diseases. When looking for a possible cause for this phenomenon, scientists soon focused on the neurotoxin BMAA, found in cycad tree fruits, an important food source in Guam. BMAA is a non- proteinogenic amino acid produced by cyanobacteria that can be enriched via the food chain in plants, seafood and higher animals. This is a critical factor because cyanobacteria are known for their excessive blooms not only in marine ecosystems but also in lakes that are used as fresh water source for millions of people.. Continue reading Talk by A. Korn at UL (February 21, 2017). ...
1DAM: Crystal structure of two quaternary complexes of dethiobiotin synthetase, enzyme-MgADP-AlF3-diaminopelargonic acid and enzyme-MgADP-dethiobiotin-phosphate; implications for catalysis.
Native: indigenous.. Non-native: introduced (intentionally or unintentionally); has become naturalized.. County documented: documented to exist in the county by evidence (herbarium specimen, photograph). Also covers those considered historical (not seen in 20 years). State documented: documented to exist in the state, but not documented to a county within the state. Also covers those considered historical (not seen in 20 years).. Note: when native and non-native populations both exist in a county, only native status is shown on the map.. ...
Largest database of Emollients Demulcents and Protectants listed for your easy reference. Find your preferred Emollients Demulcents and Protectants right here.
A terapia fotodinâmica antimicrobiana (aPDT) está-se a tornar uma alternativa promissora para inactivar microrganismos patogénicos. Esta terapia consiste na combinação de três elementos não tóxicos, fotosensibilizadores (PS), luz e oxigénio que, quando combinados conduzem à formação de espécies reactivas de oxigénio altamente citotóxicas, nomeadamente o oxigénio singuleto. Estas espécies podem oxidar muitos tipos de moléculas biológicas, como o caso de proteínas, ácidos nucleicos e lípidos. A combinação de grupos com cargas positivas e hidratos de carbono com derivados porfirínicos resulta num aumento de reconhecimento celular e solubilidade em água, melhorando a penetração na membrana celular e acumulação em compartimentos sub-celulares. O objectivo deste trabalho foi sintetizar novos derivados porfirínicos mesoglicosil substituídos e avaliar a eficácia destes compostos como PS na fotoinactivação de duas bactérias gram positivas ambientais, Brevibacterium sp. ...
Shop Osmoregulated proline transporter ELISA Kit, Recombinant Protein and Osmoregulated proline transporter Antibody at MyBioSource. Custom ELISA Kit, Recombinant Protein and Antibody are available.
Cystinuria is a health condition characterized by increased concentration of cystine and other dibasic amino acids in the urine. It most commonly occurs in young adults between the age of twenty and thirty years, although some individuals may present as children or in adolescence.
Trouver un emploi Guam avec Stages-Emplois, votre moteur de recherche emploi Guam, toutes les offres demploi Guam référencées pour trouver le job de vos rêves.
Biopeptide Complex - contains a valuable combination of oligopeptides and polypeptides, which provide immediate and long-lasting moisturization in all the layers of the skin, and also prevents sagging skin. Peptides are used to carry active ingredients deep into the skin, resulting in a deeply nourished skin, an elastic and firm body, filling in fissures and unevenness. They also have energizing properties, stimulating skin cells to produce collagen and elastin. They help fight discoloration, effectively brighten and even skin colouring.. Ectoine - has a protective and stabilizing action. As a natural substance it has strong actions protecting DNA and human cell membranes. It protects against the negative influence of external phenomena: extreme temperatures, UV radiation, the effects of ever-present viruses and bacteria. In addition to strong protective properties, ectoine is also used to relieve allergy symptoms. This ingredient is also used in dermatology, where it plays an important role in ...
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On Saturday, May 7, 2016 volunteers from the ECTA joined other community groups to plant 200 trees, and dedicate a bench to local champions Steve Revell, Bill Dinwoody, and Frank Smedley. Trees were planted in their honour at the Woolen Mills Conservation Area in Erin. Thank you to everyone who participated and supported the event.. ...
GenBank) UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase (UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase)(Meso-diaminopimelate-adding enzyme) (Meso-A2pm-adding enzyme) (UDP-N-acetylmuramyl-tripeptide synthetase) (UDP-MurNAc- ...
Synthesis of Multivalent Glycoconjugates Containing the Immunoactive LELTE Peptide: Effect of Glycosylation on Cellular Activation and Natural Killing by Human Peripheral Blood Mononuclear Cells., Renaudet, Olivier, Krenek Karel, Bossu Isabelle, Dumy Pascal, Kadek Alan, Adamek David, Vanek Ondrej, Kavan Daniel, Gazak Radek, Sulc Miroslav, et al. , J. Am. Chem. Soc., Volume 132, Number 19, p.6800-6808, (2010) ...
To develop radioimmunoassays (RIAS) for the measurement of the striped and white bass major reproductive hormones, the gonadotropins (GtH-I&II). To enable monitoring GtH levels in striped and white bass broodfish exposed to environmental or hormonal manipulations. To use a novel recombinant DNA approach for expressing immunoactive GtHs and for developing RIAs for fish gonadotropins.
Plants of Spain by Color - Pflanzen von Spanien nach Farbe - Plantas de Espa a por Color - V xter i Spanien efter f rg - Espanjan kasveja v rin mukaan
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer ...
紀伊半島の筋萎縮性側索硬化症/パーキンソン痴呆複合(ALS/PDC)の同一家系3剖検例の検討. 紀伊ALS/PDCは家族性tauopathyか? (1999 ...
FAM226A (family with sequence similarity 226 member A (non-protein coding)), Authors: Dessen P. Published in: Atlas Genet Cytogenet Oncol Haematol.
Bayesian length-weight: a=0.00661 (0.00312 - 0.01398), b=3.01 (2.83 - 3.19), in cm Total Length, based on LWR estimates for this (Sub)family-body shape (Ref. 93245 ...