Alpha-tocopherol, a lipid soluble antioxidant, has been shown to protect endothelial cells against oxidative damage (18-21). Previous reports showed that alpha-tocopherol supplementation restored endothelial function in parallel with suppression of lipid peroxidation in low density lipoproteins (LDL) in experimental hypercholesterolemic animals (19,21). In this regard, the present study also showed that the improvement of endothelium-dependent vasodilation was associated with decrease in plasma TBARS levels, an indicator of lipid peroxidation, after alpha-tocopherol treatment in patients with high remnants levels. This strongly suggests that the beneficial effect of alpha-tocopherol, as shown in the present study, was at least partly mediated through prevention of endothelial function from oxidative stress-induced injury in patients with high remnant lipoproteins levels. We have previously shown that oxidatively modified LDL causes endothelial dysfunction and has an important role in ...
TY - JOUR. T1 - Alpha-tocopherol supplementation decreases the oxidative susceptibility of LDL in renal failure patients on dialysis therapy. AU - Islam, Kazi Nazrul. AU - OByrne, Dawn. AU - Devaraj, Sridevi. AU - Palmer, Biff. AU - Grundy, Scott M.. AU - Jialal, Ishwarlal. PY - 2000. Y1 - 2000. N2 - Atherosclerotic cardiovascular disease is the leading cause of death in patients with end stage renal disease (ESRD) who have undergone dialysis treatment. The oxidation of low density lipoprotein (LDL) appears to be a crucial step in the pathogenesis of atherosclerosis. The increased oxidative stress and attendant increased oxidizability of lipoproteins, such as LDL could contribute to the accelerated atherosclerosis in dialysis patients. Since α-tocopherol (AT) is the major antioxidant in LDL, the aim of the present study was to test the effectiveness of RRR-AT supplementation (800 I.U. per day) for 12 weeks on the susceptibility of LDL to oxidation. The study subjects comprised patients with ...
Epidemiological and experimental studies have indicated that dietary factors such as vitamin C, vitamin E, and b ta-carotene are associated with the risk of colorectal cancer. This study was carried out within the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study ATBC Study, whose participants were randomly assigned to four...
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Abstract: alpha-Tocopherol reduced distinctly the intensity and duration of the stress reaction. Preadministration of alpha-tocopherol into animals before stress prevented the corticosterone elevation as well as the catecholamine decrease in heart muscle and adrenal glands; at the same time, the vitamin reduced 2-fold the duration of eosinopenia. Besides, the intensity of NA-3N neuronal uptake was twice increased in these tissues ...
Koll, Michael, Patel, Vinood B., Sherwood, R.A., Seitz, H.K., Simanowski, U.A., Richardson, P.J., Peters, T.J. and Preedy, Victor R. (2001) Alpha-Tocopherol supplementation does not prevent acute alcohol-induced heart muscle damage. Proceedings of the Nutrition Society, 60. P125A. ISSN 0029-6651 ...
The human a-tocopherol transfer protein (h-a-TTP) is understood to be the entity responsible for the specific retention of a-tocopherol (a-toc) in human tissues over all other forms of vitamin E obtained from the diet ...
CAS: 59-02-9 Molecular Formula: C29H50O2 Molecular Weight (g/mol): 430.7 MDL Number: MFCD00072045 InChI Key: GVJHHUAWPYXKBD-IEOSBIPESA-N Synonym: +-alpha-tocopherol, 2r,4r,8r-alpha-tocopherol, 5,7,8-trimethyltocol, alpha-tocopherol, d-alpha-tocopherol, dl-a-tocopherol, eprolin, phytogermine, r,r,r-alpha-tocopherol, vitamin e PubChem CID: 14985 ChEBI: CHEBI:18145 IUPAC Name: (2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-ol SMILES: CC1=C(C(=C2CCC(OC2=C1C)(C)CCCC(C)CCCC(C)CCCC(C)C)C)O ...
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The original one-room school was established in 1848 by Enoch Turner (1792-1866), a wealthy brewer and philanthropist, to educate the children in the poor neighbourhood surrounding his brewery.[2] Because many of the areas immigrant families were from County Cork in Ireland, the neighbourhood became known as Corktown - a nickname it still carries today.[2] Turner supplied the funds to construct the Schoolhouse and the land was donated by the adjacent Little Trinity Church.[3][2] In 1849, the school opened with space for 240 pupils and Turner paid for its operation for three years.[2] It was the first free school in Toronto.[4][2] Enoch Turner founded his free school following the Common Schools Act of 1846. After the act was passed, municipalities had the power to raise funds for public education through taxation. However, city officials were unwilling to introduce such taxes, and as a result, all schools that benefited from any kind of public support were closed for a year. This prompted ...
Looking for online definition of a-tocopherol in the Medical Dictionary? a-tocopherol explanation free. What is a-tocopherol? Meaning of a-tocopherol medical term. What does a-tocopherol mean?
This page contains the abstract Human Plasma and Tissue Alpha-tocopherol Concentrations in Response to Supplementation with Deuterated Natural and Synthetic Vitamin E http://www.chiro.org/nutrition/ABSTRACTS/Human_Plasma_and_Tissue_Alpha.shtml
Enzymatic syntheses of water-soluble alpha-tocopheryl glycosides were carried out in di-isopropyl ether using amyloglucosidase from Rhizopus mold or beta-glucosidase isolated from sweet almond. Optimum conditions for the amyloglucosidase were: alpha-tocopherol 0.5 mmol, D: -glucose 0.5 mmol, 400 activity unit (AU) amyloglucosidase, 0.2 mM pH 7 phosphate buffer and 72 h; and for the beta-glucosidase: alpha-tocopherol 0.5 mmol, D: -glucose 0.5 mmol, 110 AU beta-glucosidase, 0.1 mM pH 6 phosphate buffer and 72 h. Out of 11 carbohydrates employed, amyloglucosidase reacted only with D: -glucose to give 50% of 6-O-(alpha-D-glucopyranosyl)alpha-tocopherol. However, the beta-glucosidase gave 6-O-(beta-D: -glucopyranosyl)alpha-tocopherol, 6-O-(alpha-D: -galactopyranosyl)alpha-tocopherol, 6-O-(beta-D: -galactopyranosyl)alpha-tocopherol, 6-O-(alpha-D: -mannopyranosyl)alpha-tocopherol and 6-O-(beta-D: -mannopyranosyl)alpha-tocopherol in yields ranging from 10-25%. Water solubility of 6-O-(alpha-D: ...
The project is a passive follow-up of the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study cohort. Originally, this was a large, randomized, double-blind, placebo-controlled, 2x2 factorial primary prevention trial testing the effects of alpha-tocopherol and beta-carotene supplementation on cancer incidence and mortality. The study was conducted in Finland as a collaboration between the U.S. National Cancer Institute (NCI) and the National Public Health Institute of Finland. NCI has maintained passive surveillance of the cohort through Finnish national registries, including the cancer registry.. The primary purpose of the ATBC cohort follow-up is to use the existing risk factor data and biological specimens (i.e., serum, whole blood, DNA, red blood cells, and toenails) to test hypotheses relevant to cancer etiology, survival, early detection, and prevention. These data and biospecimens continue to provide an invaluable resource for the study of biochemical, nutritional, genetic, and ...
Press release - Allied Market Research - Synthetic Vitamin E Industry (Market) growth analysis By Top Key Players | BASF SE Corporation, Koninklijke DSM N.V., Eisai Food & Chemical Co.Ltd., Southwest Synthetic Pharmaceuticals Corp Ltd., Zhejiang Medicine Co Ltd. - published on openPR.com
Vitamin E has been shown to be beneficial in the prevention of cardiovascular disease (CVD). The following research is concerned with assessing vitamin E status in healthy people and those with increased risk of CVD, who may have an altered vitamin E status. To understand the relationship between vitamin E intake, blood concentrations and metabolism healthy subjects were given varying single doses of RRR alpha-tocopheryl acetate (alpha-TA) up to 780 mg (n=20). There was a greater uptake of alpha-tocopherol in plasma and erythrocytes compared with platelets and lymphocytes. No dose-response relationship was observed, however there was a positive correlation between percentage increase in a-tocopherol concentration in plasma and erythrocyte with mg urinary alpha-carboxyethylhydroxychroman (alpha-CEHC) excreted. Less than 1% of alpha-TA was excreted as urinary a-CEHC. Research into the absorption of deuterium labelled (d6) alpha-TA showed a greater uptake into plasma and chylomicrons over 9 h when ...
OBJECTIVE: The purpose of this study was to compare the effects of castration on cell death rate of the adult rat prostates and to evaluate the benefic action of alpha tocopherol supplementation to avoid apoptosis post-orchiectomy. MATERIAL AND METHODS: Thirty male Wistar rats weighing 250-300g were divided into three groups: group I - they were subjected to bilateral orchiectomy and sacrificed eight weeks after the procedure; group II - subjected to bilateral orchiectomy and alpha-tocopherol supplementation for four weeks preceding the procedure; and group III - subjected to bilateral orchiectomy and alpha-tocopherol supplementation for four weeks preceding the procedure and for eight weeks afterwards ...
MYTH: Natural Vitamins are better for the body than synthetic vitamins.. TRUTH: Not necessarily. In some cases the synthetic vitamin molecule is bio-identical to the same molecule found in nature.. Confusion arises because "natural" and "synthetic" are not opposites. The true opposite of "natural" is "artificial". Synthesis is the process by which new compounds are produced by combining simpler substances, and this can happen either in the body or in a laboratory. Synthetic vitamins can be either natural or artificial.. All synthetic vitamins A, D and E are artificial. Their molecular structures differ slightly from the same vitamins found in nature. All documented cases of toxicity from overdosing on vitamin A appear to have been from consuming artificial vitamin A. There are no documented cases of harm from consuming artificial vitamin E; however, this form of the vitamin is less efficiently utilized by the body than is natural vitamin E.. Synthetic vitamin C and all synthetic B-vitamins, ...
Synthetic vitamin E derived from petroleum products is manufactured as all-racemic alpha tocopheryl acetate with three chiral centers. This mixture has only one alpha tocopherol molecule (moiety) in 8 molecules as actual R, R,R-alpha tocopherol. The 8-isomer "all-rac" vitamin E is always marked on labels simply as "dl-tocopherol" or "dl-tocopheryl acetate", even though it is (if fully written out) actually dl,dl,dl-tocopherol. The present largest manufacturers of this type are DSM and BASF. (An earlier semisynthetic vitamin E actually contained 50% d,d,d-alpha tocopherol moiety and 50% l,d,d-alpha-tocopherol moiety, as synthesized by an earlier process which started with a plant sterol intermediate with the correct chirality in the tail, and thus resulted in a racemic mixture at only one chiral center. This form, known as 2-ambo tocopherol, is no longer made.) Natural alpha-tocopherol is the RRR-alpha (or ddd-alpha) form. The synthetic dl,dl,dl-alpha ("dl-alpha") form is not as active as the ...
Lee, S.-M. and Clemens, M. G. (1992), Effect of α-tocopherol on hepatic mixed function oxidases in hepatic ischemia/reperfusion. Hepatology, 15: 276-281. doi: 10.1002/hep.1840150217 ...
Vitamin E is necessary for ruminants to maintain a well functioning immune system, high reproduction level, and good milk and meat quality. The content of antioxidants in colostrum affects the absorption of antibodies in newborn calves. Selenium content of soils may be low, and thus home-grown forage may be low in selenium. If the roughage is also low in vitamin E, which interacts with the biological effects of selenium, deficiency may easily occur. Therefore, the rations of ruminants must be supplemented with synthetic vitamin E to ensure an adequate intake of vitamin E. However, it is known that 87,5% of the molecules of synthetic vitamin E have a non-natural configuration and is not as effective as biological vitamin E. For this reason it is important to find alternative natural vitamin and antioxidant sources that are cheap and sustainable to produce and easy to handle, especially for the organic livestock production but also for traditional livestock production. It was therefore conducted a ...
Trace amounts of Manganese (Mn) are essential for the proper functioning of a variety of physiological processes, including development, in all living organisms. However, several studies indicate that high Mn levels may be toxic to terrestrial and aquatic organisms, especially due to its neurotoxic properties. In the present study, the young and adult albino rats (2 months and 4 months old) were exposed to low dose (2.5mg/kg body weight) and high dose (5mg/kg body weight) of Mn through intraperitoneal injection for a period of 3 weeks and a separate batch treated with Mn was left for a period of one week supplementation with Alpha-tocopherol at a dose of 5mg/kg body weightalong with Mn until the end of the study.Control animals received only deionized water without Mn. In the present study, it was observed that, the potential effect of Adenosine Triphosphatase (ATPase) activity (EC 3.6.1.3); Mg2+ATPase and Na+K+ ATPase activities were assayed. From our observation, it was cleared that the ...
There are a variety of benefits to taking your Vitamin E. Vitamin E functions to help fat-soluble antioxidants. It helps to protect the cells from damage, and it may also aid in reducing other health issues such as heart disease and cancer, as well as prevention of dementia.. Vitamin E helps to improve the function of the immune system and protects the eyes and the eyesight. A study of the Dept of Epidemiology and Health Statistics of Qingdao University also found that the vitamin intake and the higher serum tocopherol levels have been linked to a lower risk of cataracts due to age.. Vitamin E also functions in creating the hormone prostaglandins which regulates many of the body processes like blood pressure and reproduction, as well as muscle contractions. In recent studies, it also helps to repair the muscles.. For those who are suffering from Crohns disease and cystic fibrosis or even an inability to get rid of the bile in the liver, this may also help them to avoid further issues with their ...
How much of Vitamin E (alpha-tocopherol) is present in Chicken, fryers or broilers, dark meat, meat with skin, raw natural in details, quantity how high or low Vitamin E (alpha-tocopherol) nutrient content it has.
How much of Vitamin E (alpha-tocopherol) is present in Cereals ready-for-eating, KELLOGGS KRAVE double chocolate cereal in details, quantity how high or low Vitamin E (alpha-tocopherol) nutrient content it has.
Wrong type of vitamins can increase risk of stroke.Intake of synthetic vitamin can increase it by 30%.So its important to get higher quality vitamin.
Do you know about Alpha-tocopherol? If not, here is a hint: Alpha-tocopherol is important to staying healthy! Read on to find out why.
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In our study, 400 IU/day of RRR-α-tocopheryl acetate administered for an average of 4.5 years to people with diabetes and at high risk for CV events had a neutral effect on CV outcomes, on microvascular complications, and on glycemic control.. The results on CV outcomes are very robust, with a large number of events and with consistent lack of benefit associated with vitamin E therapy on the composite primary outcome, on each component of the primary outcome, and on all secondary and additional CV outcomes for the entire diabetic study population and for all subgroups evaluated.. In spite of the strong biological rationale for a fundamental role of oxidative stress in atherosclerosis and the supportive epidemiological data, randomized clinical trials have overall, with few exceptions, failed to detect clear benefits of vitamin E supplementation on the progression of atherosclerotic lesions or on clinical events (8-11,15,16). While vitamin E was shown to improve endothelial function in ...
Cosmetic Analysis has rated the ingredient Tocopherol. Alternative names: Alpha-Tocopherol; a-Tocopherol; D-Alpha-Tocopherol; Vitamin E; D-MIXED-TOCOPHEROLS...
Comstock GW, Alberg AJ, Huang HY, Wu K, Burke AE, Hoffman SC, Norkus EP, Gross M, Cutler RG, Morris JS, Spate VL, Helzlsouer KJ. The risk of developing lung cancer associated with antioxidants in the blood: ascorbic acid, carotenoids, alpha-tocopherol, selenium, and total peroxyl radical absorbing capacity. Cancer Epidemiol Biomark Prev. 1997; 6(11): 907-16 ...
Unbalanced Fox news report misleads about vitamin-mineral safety By Neil E. Levin, CCN, DANLA I watched the special health report on vitamins and minerals on FOX-32 (How Do Vitamins and Minerals Really Affect Your Body? on 2/12/08, see link below), but was disappointed that the report exaggerated the risks of vitamins and minerals and minimized their benefits without any mention of the common deficiencies that exist in the American population. For example, the report cautioned about vitamin E causing blood thinning, but the Food and Nutrition Board of the Institute of Medicine has set an upper tolerable intake level (UL) for vitamin E (alpha-tocopherol) at 1,500 IU per day, which "is the highest dose unlikely to result in bleeding problems;" though the Institute has also said that the danger of the vitamin inhibiting clotting was not convincing. In other words, taking about four times the most common strength of even a hi-potency vitamin E capsule might be a problem in terms of affecting ...
In this study, antioxidant biodegradable films based on pea protein and alpha-tocopherol were successfully developed by solution casting. The effect of both the homogenization conditions (rotor-stator and microfluidizer) and the relative humidity (RH) on the microstructure and physical properties (transparency, tensile, oxygen and water vapour barrier properties) of pea protein/alpha-tocopherol-based films was evaluated. The addition of alpha-tocopherol produced minimal changes in the films transparency, while providing them with antioxidant properties and improved water vapour and oxygen barrier properties (up to 30 % in both water vapour and oxygen permeability) when films were at low and intermediate RH. The addition of alpha-tocopherol in microfluidized films gave rise to an increase in their resistance to break and extensibility (up to 27 % in E values) at intermediate and high RH. These results add a new insight into the potential of employing pea protein and alpha-tocopherol in the ...
Semantic Scholar extracted view of A liquid chromatographic method for quantitative determination of alpha-tocopherol in rat brain. by Govind T. Vatassery et al.
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Background: Circulating total cholesterol has been inversely associated with cancer risk; however, the role of reverse causation and the associations for high-density lipoprotein (HDL) cholesterol have not been fully characterized. We examined the relationship between serum total and HDL cholesterol and risk of overall and site-specific cancers among 29,093 men in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study cohort.. Methods: Fasting serum total and HDL cholesterol were assayed at baseline, and 7,545 incident cancers were identified during up to 18 years of follow-up. Multivariable proportional hazards models were conducted to estimate relative risks (RR).. Results: Higher serum total cholesterol concentration was associated with decreased risk of cancer overall (RR for comparing high versus low quintile, 0.85; 95% confidence interval, 0.79-0.91; P trend ,0.001; ,276.7 versus ,203.9 mg/dL), and the inverse association was particularly evident for cancers of the lung and ...
Learn more about Vitamin E at Grand Strand Medical Center Supplement Forms/Alternate Names Alpha Tocopherol D-Tocopherol DL-Tocopherol DL-Alpha-Tocopherol Tocopheryl...
Learn more about Vitamin E at Grand Strand Medical Center Supplement Forms/Alternate Names Alpha Tocopherol D-Tocopherol DL-Tocopherol DL-Alpha-Tocopherol Tocopheryl...
Learn more about Vitamin E at Largo Medical Center Supplement Forms/Alternate Names Alpha Tocopherol D-Tocopherol DL-Tocopherol DL-Alpha-Tocopherol Tocopheryl.....
Learn more about Vitamin E at Regional Medical Center Bayonet Point Supplement Forms/Alternate Names Alpha Tocopherol D-Tocopherol DL-Tocopherol DL-Alpha-Tocopherol Tocopheryl...
Learn more about Vitamin E at Memorial Hospital Supplement Forms/Alternate Names Alpha Tocopherol D-Tocopherol DL-Tocopherol DL-Alpha-Tocopherol Tocopheryl...
Learn more about Vitamin E at Portsmouth Regional Hospital Supplement Forms/Alternate Names Alpha Tocopherol D-Tocopherol DL-Tocopherol DL-Alpha-Tocopherol Tocopheryl...
Medical information for Tocopherol on Pediatric Oncall including Mechanism, Indication, Contraindications, Dosing, Adverse Effect, Interaction.
Internet Numbers RFC 997 Network Numbers R 192.012.024.rrr MICANET MITRE (Experimental) [WDL] R 192.012.025.rrr CSS-GRAMINAE CSS Workstation Net [16,RR2] R 192.012.026.rrr NOSC-NETR Net-R Testbed at BBN [26,CP10] R 192.012.027.rrr UR-LASER UR Laser Energetics [30,WXL] R*192.012.028.rrr RIACS-X-NET RIACS-Experimental-Net [DG28] D 192.012.029.rrr RF-EVANS ADDCOMPE DC3 LAN1 [30,MB31] D 192.012.030.rrr RF-HEX-A ADDCOMPE DC3 LAN2 [30,MB31] D 192.012.031.rrr USNA-ENET USNA Engineering Net [30,TS9] R*192.012.032.rrr CMU-VINEYARD CMU File Cluster Net [30,MXK] R 192.012.033.rrr SRI-CSL-NET SRI-CSL 10MB Ethernet [GEOF] C*192.012.034.rrr-192.012.043.rrr Schlumberger PA Net [30,RXB] R 192.012.044.rrr T NRTC-NET Northrop Research Net [30,RSM1] R 192.012.045.rrr ACC-SB-IMP-NET ACC Santa Barbara IMP [AB20] R 192.012.046.rrr ACC-SB-ETHER ACC Santa Barbara Ethernet[AB20] R 192.012.047.rrr UMN-UCC-NET Univ. of Minnesota [RG12] G 192.012.048.rrr AMES-ED-EXPNET Code ED Exp. Net. [30,MSM1] G 192.012.049.rrr ...
In most cases, processed foods arent really food at all. They are manufactured food items that are packed with chemicals, synthetic vitamins, artificial colors, and other unhealthy additives. These foods do not provide the same beneficial nutrients as fresh, whole foods. More research needs to be conducted, however, its believed that genetically modified organisms (GMO) may threaten human health. Since theyre cheaper to produce, GMO crops are generally used to produce a wide range of processed meals and snacks.. Although processed foods tend to be convenient, they produce poor eating habits. Once a person is into the routine of making meals from scratch, it is soon realized it is not as time-consuming as many believe. There are plenty of quick and easy recipes available, helping you and your family eat better. Swap those frozen dinners for a more nutrient-rich meal plan.. ...
Forty-six Holstein heifer calves were used from birth to 3 rno to study the effect of supplemental vitamin E at 1400 or 2800 mg dl-a.-tocopherol acetate given orally at weekly intervals or 1400 mg dl-a-tocopherol by ...
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