Our Orbitrap Fusion is available to support TMT based quantitative proteomics experiments, including global analysis of phosphoproteins, and weve included some example prices for TMT analysisin the cost section. This new instrument has phenomenal mass accuracy and experimental flexibility that is unmatched in the field at the moment. We also recently added a Q-Exactive HF instrument through support from an OHSU Emerging Technology Award. Were looking forward to offering the opportunity for OHSU researchers to take advantage of these capabilities.. We are now requiring all sample submissions to go through iLab, including those performed by the OHSU/PNNL colaboratory for mass spectrometry. Please see the Request Services page for more information.. Publishing results from PSR? If so, please include the following: Mass spectrometric analysis was performed by the OHSU Proteomics Shared Resource with partial support from NIH core grants P30EY010572 & P30CA069533. Your citation should also reference ...
The Picker lab is now investigating the possible reasons why only a subset of the animals treated had a positive response in hopes that the effectiveness of the vaccine candidate can be further boosted.. This research was funded by several grants from the National Institutes of Health, funding from the International AIDS Vaccine Initiative and a CAVD grant from the Bill & Melinda Gates Foundation.. In the interest of ensuring the integrity of our research and as part of our commitment to public transparency, OHSU actively regulates, tracks and manages relationships that our researchers may hold with entities outside of OHSU. In regards to this research project, OHSU has licensed a CMV technology, of which Picker is an inventor, to the International AIDS Vaccine Initiative. In addition, CMV vector technology is being commercialized by TomegaVax, Inc., a company in which both OHSU and Picker have a significant financial interest.. More information on OHSUs conflict of interest policies and ...
If youre an OHSU researcher, Technology Transfer and Business Development has two opportunities to help you move your research forward. Through partnerships with the Oregon Bioscience Association and the Technology Association of Oregon, you are invited to pitch your innovations to a crowd of local community members, entrepreneurs, and investors. In two separate events, OHSU researchers can hone their messages, craft compelling presentations, and practice their pitches. OHSU provides individualized coaching to help you succeed. Participation in such events can open doors to other opportunities through these associations and TTBDs extensive network contacts. Following are details about these upcoming events.. ...
San Francisco, CA - Its almost like the plot of a horror movie. A 25-year-old infectious disease worker left work Friday only to die the next day after being infected with the contagious bacteria he had been working with.. The man worked at the San Francisco Veterans Affairs Medical Center where, over the last few months, he had been working with a rare Neisseria meningitidis bacterial strain that causes septicemia and meningitis - both of which are nasty ways to go if left untreated.. Meningitis can lead to fever, headache, neck stiffness, coma and then death. By comparison, you would pray for this over septicemia, which is what investigators believe killed the man. Septicimia is inflammation of the bloodstream that causes bleeding into the skin and organs. A person unlucky enough to be afflicted with this blood poisoning can die very quickly from septic shock or ARDS.. Fellow employees described the man as competent and fully capable of handling the bacteria he was working with and the chief ...
Karch kept himself awake with coffee, and to relax he went for walks with his German shepherd. "Can you imagine what Im going through?" he wrote in an email to Phillip Tarr at Washington University in St. Louis. His response came at 4:27 a.m.: "Epidemics are for younger men." Tarr, the second major EHEC expert next to Karch, had also never heard of an O104:H4 outbreak.. In the email, Karch speculated over why the disease wasnt happening in children, as is normally the case, but only in adults. And why was the infection striking more people that ever before in Germany - so many, in fact, that dialysis stations in several hospitals were almost full?…. Perhaps the genetic material of this rare bacterium has mutated again, so that its toxin or its bond to the intestinal cells it damages has become stronger. ...
Officials in Wisconsin are investigating an outbreak involving a rare bacterium that may be linked to the deaths of nearly 20 people in the past few month...
OHSU first year medical school. Learn about what books to buy, which ones are useful for reference. Learn about housing, Principles of Clinical Medicine and much more!
The researchers used a vaccination method that involves creating and maintaining resistance by programming a portion of the bodys immune system - effector memory T-cells - to look out for HIV at the site of infection. "HIV appears to be vulnerable when it is first introduced into mucosal surfaces in the body," said Louis Picker, M.D., associate director of the OHSU VGTI and director of the VGTIs vaccine program. "However, once HIV spreads throughout the entire body, it replicates very rapidly and becomes difficult if not impossible to control. Our approach is to attack during this early period of vulnerability. The approach is similar to that of a homeowner who sprays their house with water before sparks land on the roof. This approach can prevent the roof from catching fire and, in the case of HIV, prevent the spread of the virus.". ...
Advice to Management. Coworkers do not create tight bonds due to long hours away from hour due to commute, so they are more focused on their personal time than making work relationships. Having worked in industry before this, the benefits that are offered do not correlate with such low non-competitive wages based on the lack of efforts by HR to mitigate costs with programs to increase employee happiness. OHSU benefits are about on par with private industry/medical standards, but most likely above university standards. HR takes advantage of the University label to excuse the non-competitive wages and expects a high employee turn over to resolve any wage issues. HR does not help with employee/supervisor issues and expects employees to leave instead of disciplining supervisors resulting in lack of communication with supervisors with bad management. HR provides a lack of training for new supervisors coming into their positions and check-in programs. Company is not sensitive to employees political ...
Hi guys, Ive been reading this forum a bunch over the past 2 weeks...what a wealth of information! I read someone talking about OHSU in Portland,...
At each site (OHSU & UM), 180 socially isolated adults 80+ years old will be recruited through Meals on Wheels People. Participants will be randomized to either the Video Chat Group or the Control Group. Those in the Video Chat Group will receive a computer for the duration of the study, which they will use to video chat with study staff for 30 minutes/day 4x/week for 6 months, and then they will video chat 2x/week for another 6 months. Those assigned to the Control Group will have brief telephone check-ins with study staff once per week. In-home testing will occur at Baseline, 6 months and 12 months. All participants at OHSU will have their medication compliance tracked using electronic medication monitoring devices (MedTracker) and 50% of participants at both OHSU and UM will have MRIs at Baseline and 6 months, if they are able to safely receive MRIs. All participants at both sites will contribute saliva for genetic testing, and all video chat sessions will be recorded for speech and language ...
Enjoy some excellent animations. The virology animation includes viral replication. Viral styles of replication are complex and fascinating, also providing a target for therapeutic intervention ...
Will 1.5 T become the new Low field MRI? These new Ultra High field systems continue to amaze me. I saw this 12T system a few years ago being installed and really was amazed at how far we have come. The 7T scanner is actually more impressive because it is closer to being a production…
PNNL and OHSU combined omics measurements with novel computational network analysis to better understand Salmonella regulatory interactions, identify virulence-related proteins causing systemic infection.
Dr. Glen Kisby (Professor of Pharmacology, COM) and his colleague Dr. Jacob Raber (Department of Behavioral Neuroscience, OHSU) are investigating the link
When it was time for me to leave the Broad (and come to OHSU), I went through my old experimental files and realized that I had in fact done a TERRIBLE job of keeping track of everything, and that I was the only one who would ever be able to navigate the mess I had created. Each experiment had well over a dozen associated documents and piles of different versions (ExptResults, ExptResults_Real, ExptResults_Real_Final, etc), and the naming system was effectively incoherent, and I couldnt figure out which experiment went with which mass spec datafile, and oh god it was a mess ...
Improper handling of intravenous saline at a West Virginia outpatient oncology clinic was linked with the first reported outbreak of Tsukamurella spp., gram-positive bacteria that rarely cause disease in humans, in a new report from the Centers for Disease Control and Prevention (CDC). The report was published in the March issue of Infection Control and Hospital Epidemiology.
Oregon Health & Science University researchers have identified som... For many years scientists have understood that damage to the insulat...Other key OHSU researchers involved in the study are: Stephen Back M....The researchers decided to collaborate following a key finding in Sher...,OHSU,researchers,discover,potential,mechanism,to,repair,brain,damage,linked,to,Multiple,Sclerosis,biological,biology news articles,biology news today,latest biology news,current biology news,biology newsletters
Annual OHSU Colloquium on Neuromuscular Disorders is organized by Oregon Health And Science University (OHSU) and will be held on Feb 17, 2018 at Portland State University Collaborative Life Sciences Building, Portland, Oregon, United States of America.
...Researchers at Oregon Health & Science U...The new discovery is published online in Neuroscience: A HREF...In their study the OHSU team looked at glial cells non-neuronal cell... Previous research has shown that a common feature of the brains of SI...,OHSU,discovery,may,someday,lead,to,prevention,and,treatment,of,sudden,infant,death,syndrome,biological,biology news articles,biology news today,latest biology news,current biology news,biology newsletters
American families may have been exposed to a rare bacteria after playing with and fostering puppies rescued from Puerto Rico. Two of the puppies,...
Oregon brain researcher Dr. Stephen Back got some great news recently. It was the academic equivalent of winning the lottery. What the OHSU doctor won was the Javitz Neuroscience Investigator Award. Unlike the lottery the award is quite prestigious. But like the lottery, the federal grant also means a lot of cash.. Two million, three hundred and forty-six thousand, three hundred and thirteen dollars to be exact. Back says his research into brain injuries using tissue and animal models is especially relevant for the 60,000 premature babies born every year in the U.S. Theyre at especially high risk of cerebral palsy.. Dr. Back talked with Oregon Considered host Allison Frost about the award. ...
This is a key study that helps us understand one additional immunosuppressive strategy that can be used. Every patient has different reactions when they receive a new heart, so its valuable to have several options that allow us to tailor our treatment to their needs," said Hershberger, director of the OHSU Heart Failure and Cardiac Transplantation Program and professor of medicine (cardiology) at the OHSU School of Medicine. His team enrolled more than 30 patients in the study, the largest number from one medical center ...
ORIGINAL ARTICLEBicycle Commuter Injury Prevention: It Is Time to Focus on the Environment Melissa R. Hoffman, ND, MD, William E. La...
Oregon Health & Science University today released an iPhone app designed to advance melanoma research by giving users the ability to accurately measure and monitor moles, and contribute photos of how their potential trouble spots evolve over time. Called Mole Mapper, the app is free to download from the App Store and was developed using ResearchKit, an open source framework developed by Apple.
Axthelm, M.. National Institutes of Health. 8/1/16 → 7/31/20. Project: Research project › Animal (Mammalian and Nonmammalian) Model, and Animal and Biological Materials Resource Cooperative Agreements ...
Axthelm, M.. National Institutes of Health. 8/1/16 → 7/31/20. Project: Research project › Animal (Mammalian and Nonmammalian) Model, and Animal and Biological Materials Resource Cooperative Agreements ...
PORTLAND, Ore. - Researchers at Oregon Health & Science University have discovered that a form of cell division typically associated with cancer called multipolar mitosis can yield diverse, viable cells capable of protecting the liver from injury and poisonous substances, such as pesticides, carcinogens or drugs. Their findings are published online in the journal Nature.. "Our findings show that the liver, which is known to have a tremendous capacity for regeneration, also has an amazing degree of diversity. A better understanding of this process may reveal why some individuals are more susceptible to different forms of liver injury than others, which could lead to new therapies for the treatment of liver disease," said Andrew Duncan, Ph.D., principal investigator and postdoctoral researcher in the lab of Markus Grompe, M.D., Papé Family Pediatric Institute, OHSU Doernbecher Childrens Hospital; and the Oregon Stem Cell Center at OHSU.. The liver comprises a pool of genetically distinct ...
Matt Jones ,jonesmat at ohsu.edu, wrote: , ,This brings me to another question about standard neural net modelling. ,How is timing incorporated into most models? From the basic course I took ,many years ago, I remember that the entire network would be stepped ,simultaneously, all the inputs and their weighting would be calculated to ,produce the output of each neuron, and then the whole network would be ,stepped again. If this is still the way most of the modelling is being ,done, its pretty different from the situation in the brain (not wrong, ,just different). Actually, its kind of like what would happen if you ,considered the biological activity in time units that were really long ,compared to the durations of most synaptic events (time windows of 100s ,of milliseconds). As if you passed the biological system through a 5 Hz ,low pass filter. You filter out the spikes, and instead of rate coding ,(or whatever the latest theory is) you get outputs that are graded ,according to the input ...
Portland oregon has a program at PCC. Robyn OHSU _______________________________________________ Histonet mailing list [email protected] http://lists.utsouthwestern.edu/mailman/listinfo/histonet ...
Hi, I was wondering if someone had generated constructs which target GFP to the mitochondria. We would like to use this to follow segregation of mitos during cell division. Mike Forte -- Mike Forte forte at ohsu.edu or forte at mtwo.com ...
Cedecea is a genus of extremely rare bacteria of the family Enterobacteriaceae. The name of this genus was derived from CDC, the abbreviation for the Centers for Disease Control where the initial members of this genus were discovered. This genus resembles no other group of Enterobacteriaceae. Cedecea bacteria are Gram-negative, bacillus in shape, motile, nonencapsulated, and nonspore-forming. The strains of Cedecea appear to be similar to those of Serratia. Both Cedecea and Serratia are lipase positive and resistant to colistin and cephalothin; however, Cedecea is unable to hydrolyze gelatin or DNA. Cedecea bacteria were discovered in 1977 by a group of scientists at the CDC and were initially named "Enteric Group 15". In 1980, Patrick A. D. Grimont and Francine Grimont proposed the genus name of Cedecea for this group. This particular name was given to "Enteric Group 15" for the abbreviation of the Center for Disease Control (CDC) where the group of bacteria was discovered. At this time, six ...
We show in this study that P. aeruginosa, already known for its swimming and twitching motility, is also able to propagate on semisolid surfaces by swarming. This makes P. aeruginosa one of the rare bacteria to possess three types of motility. Swarming, described so far only for peritrichously flagellated organisms, requires in P. aeruginosa the interplay of several features, namely amino acids as a nitrogen source, the presence of both flagella and type IV pili, and the secretion of rhamnolipids as a surface-active compound.. The surprising finding that P. aeruginosa swarmer cells can express two polar flagella is in agreement with a recent report of afleN mutant of P. aeruginosa (13) which was found to express between three and six polar flagella. Although the fleN mutant was nonmotile, this observation suggests that flagellum number is indeed regulated in this organism. Swarming could be a natural situation where flagellum upregulation could provide a more efficient propagation on semisolid ...
It is an exciting development to see several technologies converge on this challenge so elegantly, says Kyle Ellrott, researcher with the OHSU Knight Cancer Institute, assistant professor at the OHSU School of Medicine, and one of the challenge leaders. The cloud pilots are available to provide access to scalable compute to large datasets. With the SMC-Het, and now SMC-RNA, we employ an evaluation mechanism that produces reproducible bioinformatics methods. The results of these challenges can be used to solve important problems in cancer genomics. And at the end of the challenge any of the submitted techniques could be made available to the users the cloud pilots for them to apply to their own data. It is truly a dynamic combination that is set to accomplish great things.. The Ontario Institute for Cancer Research (OICR) is the central coordinating agency of the DREAM Challenge, led by Dream Challenge Director Dr. Paul Boutros of OICR.. ###. About the OHSU Knight Cancer Institute. The Knight ...
David Dilts, PhD, MBA, Professor in the Division of Management at Oregon Health & Science University and a member of the OHSU Knight Cancer Institute management team, received a 2011 group merit award from the National Institutes of Health for his role in developing AccrualNet, a web-based system designed to help researchers navigate the process for recruiting participants to NIH clinical trials. He and the other co-developers were presented with the award during a ceremony in Bethesda.. "It is gratifying to see David Dilts work on this project receive such a prestigious award," Brian Druker, MD, Director of the OHSU Knight Cancer Institute, said in a statement. "Improving the speed of completing clinical trials is crucial to accelerating progress against cancer, especially as cancer treatments become more specialized.". One of Dr. Dilts responsibilities within the OHSU Knight Cancer Institute is to help foster national efforts to streamline clinical trials to help advance personalized cancer ...
Strain JC163T exhibited catalase activity but not oxidase activity. Using the API 20E system, positive reactions were obtained for indole production, β-galactosidase and glucose, mannitol, sorbitol and rhamnose fermentation. E. massiliensis is susceptible to ticarcillin, imipenem, trimethoprim/sulfamthoxazole, gentamicin, amikacin, and colimycin but resistant to fosfomycin and nitrofurantoin. By comparison with E. arachidis, its phylogenetically-closest neighbor, E. massiliensis differed in arginine dihydrolase, ornithine decarboxylase, citrate and succinate fermentation [19].. Matrix-assisted laser-desorption/ionization time-of-flight (MALDI-TOF) MS protein analysis was carried out as previously described [52]. Briefly, a pipette tip was used to pick one isolated bacterial colony from a culture agar plate and spread it as a thin film on a MTP 384 MALDI-TOF target plate (Bruker Daltonics, Germany). Twelve distinct deposits were done for strain JC163T from twelve isolated colonies. Each smear ...
One of the genes that influences drug physical dependence and associated withdrawal has been identified at Oregon Health & Science University. The gene, Mpdz, is involved in physical dependence on a class of drugs known as sedative-hypnotics.
OHSU already holds Warbasses The doctor and the public, published in 1935. Surgical treatment was really the culmination of Warbasses thought on the practice of medicine and the technic of surgery in his day. In the preface, he writes: "Surgery is an art based upon a complex of sciences. It is always in a developmental stage. Accordingly the author has endeavored to inspire the reader with the spirit of originality, to teach him not only how to do, but to suggest to him new lines of action, to set him thinking on the problem of treatment from his own standpoint ...
Hi, Julia.. We had a similar issue. David did not have the gene deletions (1p, 19q) that would make Temodar more effective. Different mutation since we are battling anaplastic oligodendroglioma, not AA3, but still the same difficult choice. We did Temodar anyway. I also was devastated when Davids FISH evaluation came back without the deletions. Our doctor at OHSU strongly recommended taking Temodar, but another doctor thought we should just do radiation and save Temodar for later. Our doctor strongly disagreed and told us that Temodar and radiation would have a synergistic effect if taken together. So thats what David did---he took Temodar while he did radiation, and then he continued to take it until April of this year.. I am glad that we did Temodar. I believe that it was the right choice for us. We knew going in that the doctors expected it to only be effective for a short time. But they told us that about every chemo. David had two years and 5 months with no tumor progression---no tumor at ...
In May 2005, he pieced inverted one of Canadas Big 40 under 40 therapies environmental in Canada by the Caldwell Partners and the Globe and Mail. In 2006, Murad was gathered a Saskatchewan Centennial Medal as an infectious growth engagement by Saskatchewans Lieutenant- Governor. Al-Katib saw from the University of Saskatchewan with a Bachelor of Commerce with Distinction in Finance and heard his Master of International Management with Distinction from the American Graduate School of International Management( Thunderbird) in Arizona. With over 25 relationships of illness age loyalty, Michaels outbreak dates allowing in high rare bacteria at anatomy, strict hair, interesting and Holistic dynamics. He tends given readable in company effects, gain and cell odometer. He allows a Master of Business Administration image from the University of Manitoba and is explained by Airports Council International( ACI) and the International Civil Aviation Organization( ICAO) as an International Airport ...
ORANGE COUNTY, Texas - Gean Hammet and his family has experienced a community coming together, most recently while his daughter Raylee spent more than seven weeks at Texas Childrens Hospital with a rare bacteria.. "Were trying to raise some money to help with the financial burden that we still do you have after going back-and-forth to Houston for her medical appointments plastic surgery and all that good stuff," said Hammett.. Now the toddler is home and life is back to normal, except for the stack of medical bills the family now faces as a result of 30 nights stay in intensive care, 50 nights total.. Patricia, Raylees mom, spoke about the overwhelming support her family has received lately. "Yeah were so grateful and blessed so I tell people were just so blessed to be able to bring her daughter home with all the prayers she really is a miracle," she said.. This weekend the family is hosting a ragball tournament this in Bridge City. Games start at 9a.m. Sunday morning at the Bridge City ...
Yoga Reduces Fatigue In Multiple Sclerosis Patients, OHSU Study FindsScienceDaily (June 10, 2004) - PORTLAND, Ore. -- Just six months of yoga significantly reduces fatigue in people with multiple sclerosis, but it has no effect on alertness and cognitive function, says a new Oregon Health & Science University study. The study, published June 8 in…
This August 2016 photo provided by Oregon Health & Science University (OHSU) shows inflammation (in the circle added by the source) from the infection caused by Thelazia gulosa, a type of eye worm seen in cattle in the northern United States and southern Canada, inside of the eyelid of a woman. The Oregon woman who had worms coming out of her eye is being called the first known human case of a parasitic infection spread by flies. Fourteen tiny worms were removed from the left eye of the 26-year-old woman in August 2016. Scientists reported the case Monday, Feb. 12, 2018. (OHSU via AP) less ...
This August 2016 photo provided by Oregon Health & Science University (OHSU) shows inflammation (in the circle added by the source) from the infection caused by Thelazia gulosa, a type of eye worm seen in cattle in the northern United States and southern Canada, inside of the eyelid of a woman. The Oregon woman who had worms coming out of her eye is being called the first known human case of a parasitic infection spread by flies. Fourteen tiny worms were removed from the left eye of the 26-year-old woman in August 2016. Scientists reported the case Monday, Feb. 12, 2018. (OHSU via AP) less ...
https://www.ibiology.org/human-disease/imatinib-paradigm-targeted-cancer-therapies/#part-2 Imatinib (Gleevec) has become a paradigm for targeted cancer thera...
The day after Christmas, I had my first speech language pathology appointment with the swallowing clinic at OHSU. The therapist ...
Study MedTermReview - Intermediate flashcards from Stacy Abraham's OHSU class online, or in Brainscape's iPhone or Android app. ✓ Learn faster with spaced repetition.
Robinson, G. W. "SV40 chromatin structure in intact cells and virus particles as probed by psoralen photaddition" (1983). OHSU Digital Collections. https://doi.org/10.6083/M4NS0S1M ...
Dr. Rebecca Spain, a neurologist, did a postdoctoral fellowship in MS at Thomas Jefferson University in Philadelphia; Dr. Edward Kim finished a two-year fellowship with the MS Center and is staying on as faculty; and Dr. Michelle Cameron is a National MS Society funded Sylvia Lawry Fellow. With the addition of the new physician staff, OHSU ...
20 Registered Nurse Forest Grove, OR, USA At Tuality Healthcare, an OHSU Partner, its an honor and a privilege to serve those near us. Thats why since our beginnings in 1918, and as we expand our strong network of services through our ...... Apply Now>> ...