ADP glucose pyrophosphorylase 1 (ADG1); FUNCTIONS IN: glucose-1-phosphate adenylyltransferase activity; INVOLVED IN: photoperiodism, flowering, starch biosynthetic process; LOCATED IN: heterotetrameric ADPG pyrophosphorylase complex, apoplast, chloroplast, chloroplast stroma; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Glucose-1-phosphate adenylyltransferase (InterPro:IPR011831), ADP-glucose pyrophosphorylase, conserved site (InterPro:IPR005836), Nucleotidyl transferase (InterPro:IPR005835); BEST Arabidopsis thaliana protein match is: ADP glucose pyrophosphorylase large subunit 1 (TAIR:AT5G19220.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink ...

Involved in the biosynthesis of ADP-glucose, a building block, required in the biosynthesis of maltose-1-phosphate (M1P) and in the elongation reactions to produce linear alpha-1,4-glucans. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

MORÁN ZORZANO, María Teresa (2006) ADPglucose metabolism in bacteria and plants. PhD thesis, UPNA.. Texto completo no está disponible desde este repositorio ...

I am new to Cedar Park and needed to find a new vet for my pets, one of whom has special needs. As soon as I took the tour, I was hooked. Friendly, knowledgeable staff, and the cleanest vet clinic Ive been in.-Chelaine. Loved the TLC and patience given!-Kathy. The staff and Dr.s are always friendly and we are taken back almost as soon as we get there.-Anonymous. I have been coming to Dr. Schubert for 8 years and she has shown nothing but genuine concern and caring for my animals, through life and death. The staff is also personable and caring, always putting your pet first.-Anonymous. You definitely get the feeling as though they treat your pet as if it were their own.-Sean. We are new to having a fur companion and had lots of questions and concerns regarding our puppy. CCPC addressed the ones that we could remember along with what to expect and their recommendations. -Christel. My pets are part of my family, and Dr. Bouloy really understands. He and his staff are always caring and never too ...

Thymidine diphosphate glucose (often abbreviated dTDP-glucose or TDP-glucose) is a nucleotide-linked sugar consisting of deoxythymidine diphosphate linked to glucose. It is the starting compound for the syntheses of many deoxysugars. DTDP-glucose is produced by the enzyme glucose-1-phosphate thymidylyltransferase and is synthesized from dTTP and glucose-1-phosphate. Pyrophosphate is a byproduct of the reaction. DTDP-glucose goes on to form a variety of compounds in nucleotide sugars metabolism. Many bacteria utilize dTDP-glucose to form exotic sugars that are incorporated into their lipopolysaccharides or into secondary metabolites such as antibiotics. During the syntheses of many of these exotic sugars, dTDP-glucose undergoes a combined oxidation/reduction reaction via the enzyme dTDP-glucose 4,6-dehydratase, producing dTDP-4-keto-6-deoxy-glucose. Xue M. He & Hung-wen Liu (2002). Formation of unusual sugars: Mechanistic studies and biosynthetic applications. Annu Rev Biochem. 71: 701-754. ...

Two mutants of Arabidopsis have been isolated that affect ADPG pyrophosphorylase (ADGase) activity. Previously, it has been shown that ADG2 encodes the large subunit of ADGase. This study characterizes the adg1 mutant phenotype and ADG1 gene structure. RNA blot analyses indicate that the adg1-1 muta …

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Author: Trethewey, R. N. et al.; Genre: Journal Article; Published in Print: 1999; Keywords: adpglucose pyrophosphorylase|br/|glycolysis|br/|invertase|br/|partitioning|br/|potato tubers|br/|starch metabolism|br/|sugar signalling|br/|increased adpglucose pyrophosphorylase|br/|yeast-derived invertase|br/|solanum-tuberosum|br/|tobacco plants|br/|gene-expression|br/|metabolism|br/|glucose|br/|leads|br/|carbohydrate|br/|accumulation; Title: Induction of the activity of glycolytic enzymes correlates with enhanced hydrolysis of sucrose in the cytosol of transgenic potato tubers

A key intermediate in carbohydrate metabolism. Serves as a precursor of glycogen, can be metabolized into UDPgalactose and UDPglucuronic acid which can then be incorporated into polysaccharides as galactose and glucuronic acid. Also serves as a precursor of sucrose lipopolysaccharides, and glycosphingolipids.

Literature References: The coenzyme of the galactowaldenase system which catalyzes the conversion of galactose-1-phosphate into glucose-1-phosphate. Isoln from bakers yeast: Caputto et al., J. Biol. Chem. 184, 333 (1950). Also present in animal tissue. Synthesis: Michelson, Todd, J. Chem. Soc. 1956, 3459; Moffatt, Khorana, J. Am. Chem. Soc. 80, 3756 (1958). Reviews: Leloir, Cardini in The Enzymes vol. 2A, P. D. Boyer et al., Eds. (Academic Press, New York, 2nd ed., 1960) pp 39-61; A. M. Michelson, The Chemistry of Nucleosides and Nucleotides (Academic Press, New York, 1963) pp 153-250; D. W. Hutchison, Nucleotides and Coenzymes (John Wiley, New York, 1964) pp 36-82. ...

Lunn, J. E.; Feil, R.; Hendriks, J. H. M.; Gibon, Y.; Morcuende, R.; Osuna, D.; Scheible, W.-R.; Carillo, P.; Hajirezaei, M.-R.; Stitt, M.: Sugar-induced increases in trehalose 6-phosphate are correlated with redox activation of ADPglucose pyrophosphorylase and higher rates of starch synthesis in Arabidopsis thaliana. Biochemical Journal 397 (1), S. 139 - 148 (2006 ...

Lunn, J. E.; Feil, R.; Hendriks, J. H. M.; Gibon, Y.; Morcuende, R.; Osuna, D.; Scheible, W.-R.; Carillo, P.; Hajirezaei, M.-R.; Stitt, M.: Sugar-induced increases in trehalose 6-phosphate are correlated with redox activation of ADPglucose pyrophosphorylase and higher rates of starch synthesis in Arabidopsis thaliana. Biochemical Journal 397 (1), S. 139 - 148 (2006 ...

1972). Plant Physiol. 49, 249-251. Macdonald, F. , (1983a). Biochim. Biophys. Acta 755, 81-89. Macdonald, F. , and ap Rees, T. (1983b). Phytochemistry 22, 1141-1143. Macdonald, F. , and Preiss, J. (1983). Plant Physiol. 73, 175-178. Manners, D. J. (1985). In Biochemistry of Storage Carbohydrates in Green Plants (P. M. Dey and R. A. ), pp. 149-203. Academic Press, New York. Mettler, I. , and Beevers, H. (1980). Plant Physiol. 66, 555-560. , and Copeland, L. (1984). Plant Physiol. 74, 1030-1034. In Regulation of Carbon Partitioning in Photosynthetic Tissues (R. L. Heath and J. ), pp. 231-253. Waverly Press, Baltimore. Ziegler, H. (1975). Encycl. Plant Physiol. 1, 59-136. Recent Advances in Sugar Transport 2 W. J. LUCAS M. A. MADORE I. Introduction II. Sucrose: The Ubiquitous Transport Sugar A. Chemical Structure B. Surface Structure C. Carrier Recognition III. Carrier-Mediated Sugar Transport Mechanisms A. Photosynthesizing Tissues B. Storage Tissues IV. Group Translocator Concept for Sucrose ...

"We would be very, very thankful if you brought it back," Lindsay Preiss said. "I'm just asking someone to please have it in your heart to do the right thing and give it back."

Harn Chee Hark , Bae Jung Myung , Lee Sang Sook , MIN Sung Ran , LIU Jang Ryol Plant and cell physiology 41(11), 1235-1242, 2000-11 参考文献28件 被引用文献4件 ...

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Previous studies have indicated that ADP-glucose pyrophosphorylase (ADPGlc PPase) from the cyanobacteriumAnabaena sp. strain PCC 7120 is more similar to higher-plant than to enteric bacterial enzymes

50 µCi quantities of [Glucose-14C(U)]-Uridine Diphosphate Glucose are available for your research. Application of [14C]Uridine can be found in: pyrimidine salvage and catabolism in mangrove species in plant science research, long-term effect of NaCl on the activity of uridine and uracil salvage for nucleotide synthesis in plant science research, glutathione-induced growth of embryogenic tissue of white spruce correlating with changes in pyrimidine nucleotide metabolism in plant science research, etc.. Special Information ...

50 µCi quantities of [Glucose-14C(U)]-Uridine Diphosphate Glucose are available for your research. Application of [14C]Uridine can be found in: pyrimidine salvage and catabolism in mangrove species in plant science research, long-term effect of NaCl on the activity of uridine and uracil salvage for nucleotide synthesis in plant science research, glutathione-induced growth of embryogenic tissue of white spruce correlating with changes in pyrimidine nucleotide metabolism in plant science research, etc.. Special Information ...

10 µCi quantities of [Glucose-14C(U)]-Uridine Diphosphate Glucose are available for your research. Application of [14C]Uridine can be found in: pyrimidine salvage and catabolism in mangrove species in plant science research, long-term effect of NaCl on the activity of uridine and uracil salvage for nucleotide synthesis in plant science research, glutathione-induced growth of embryogenic tissue of white spruce correlating with changes in pyrimidine nucleotide metabolism in plant science research, etc. Special Information ...

Antisense oligodeoxynucleotide (ODN) inhibition emerges as an effective means for probing gene function in plant cells. Employing this method we have established the importance of the SUSIBA2 transcription factor for regulation of starch synthesis in barley endosperm, and arrived at a model for the role of the SUSIBAs in sugar signaling and source-sink commutation during cereal endosperm development. In this addendum we provide additional data demonstrating the suitability of the antisense ODN technology in studies on starch branching enzyme activities in barley leaves. We also comment on the mechanism for ODN uptake in plant cells. Antisense ODNs are short (12-25 nt-long) stretches of single-stranded ODNs that hybridize to the cognate mRNA in a sequence-specific manner, thereby inhibiting gene expression. They are naturally occurring in both prokaryotes and eukaryotes where they partake in gene regulation and defense against viral infection. The mechanisms for antisense ODN inhibition are not fully

Flegr J, Hampl R, Černochová D, Preiss M, Bičíková M, Sieger L, Příplatová L, Kaňková Š, Klose J. The relation of cortisol and sex hormone levels to results of psychological, performance, IQ and memory tests in military men and women. Neuro Endocrinol Lett. 2012 Jan; 33(2): 224-235 ...

PMID:22319597 Complexity of murine cardiomyocyte miRNA biogenesis, sequence variant expression and function Humphreys DT, Hynes CJ, Patel HR, Wei GH, Cannon L, Fatkin D, Suter CM, Clancy JL, Preiss T PLoS One. 7:e30933(2012). ...

Uridine Diphosphate Glucose Dehydrogenase: An enzyme that catalyzes the oxidation of UDPglucose to UDPglucuronate in the presence of NAD+. EC 1.1.1.22.

Principal Investigator：SAGISAKA Shonosuke, Project Period (FY)：1990 - 1992, Research Category：Grant-in-Aid for General Scientific Research (B), Research Field：応用生物化学・栄養化学

Jessup M Shively, Gordon C Cannon, Sabine Heinhorst, Donald A Bryant, Shiladitya DasSarma, Dennis Bazylinski, Jack Preiss, Alexander Steinbüchel, Roberto Docampo, Christiane ...

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The first cassette comprises fragments of both the asparagine synthetase-1 gene (Asn1) and the polyphenol oxidase-5 gene (Ppo5), arranged as inverted repeats between the Agp promoter of the ADP glucose pyrophosphorylase gene (Agp) and the Gbss promoter of the granule-bound starch synthase gene (Gbss) and results in silencing of both the Ppo5 and Asn1 genes ...

casSAR Dugability of Q7XNX6 | SUS7 | Sucrose synthase 7 - Also known as SUS7_ORYSJ, SUS7. Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways.

P. Willeit, L. Tschiderer, E. Allara, K. Reuber, L. Seekircher, L. Gao, X. Liao, E. Lonn, H. C. Gerstein, S. Yusuf, F. P. Brouwers, F. W. Asselbergs, W. van Gilst, S. A. Anderssen, D. E. Grobbee, J. J. P. Kastelein, F. L. J. Visseren, G. Ntaios, A. I. Hatzitolios, C. Savopoulos, P. T. Nieuwkerk, E. Stroes, M. Walters, P. Higgins, J. Dawson, P. Gresele, G. Guglielmini, R. Migliacci, M. Ezhov, M. Safarova, T. Balakhonova, E. Sato, M. Amaha, T. Nakamura, K. Kapellas, L. M. Jamieson, M. Skilton, J. A. Blumenthal, A. Hinderliter, A. Sherwood, P. J. Smith, M. A. van Agtmael, P. Reiss, M. G. A. van Vonderen, S. Kiechl, G. Klingenschmid, M. Sitzer, C. D. A. Stehouwer, H. Uthoff, Z. Y. Zou, A. R. Cunha, M. F. Neves, M. D. Witham, H. W. Park, M. S. Lee, J. H. Bae, E. Bernal, K. Wachtell, S. E. Kjeldsen, M. H. Olsen, D. Preiss, N. Sattar, E. Beishuizen, M. V. Huisman, M. A. Espeland, Caroline Schmidt, S. Agewall, E. Ok, G. Aşçi, E. de Groot, M. P. C. Grooteman, P. J. Blankestijn, M. L. Bots, M. J. ...

1BGT: Crystal structure of the DNA modifying enzyme beta-glucosyltransferase in the presence and absence of the substrate uridine diphosphoglucose.

Ribbon representation of the structure of an enzyme known as ATP-PRT from TB bacteria (blue), bound to an allosteric activator (pink).

Maize (is activated by Fru-6-P (F-6-P) and inhibited by inorganic phosphate (Pi) whereas the AGPase is activated by Fru-1 6 but inhibited by AMP. (small subunit homotetramer; Jin et al. 2005 HA14-1 Although both buildings reveal inactive conformations because of high concentrations of ammonium sulfate in the crystallization buffer important info about potential substrate-binding sites was forecasted by molecular modeling predicated on the known buildings of thymidilyltransferases. While this course of enzymes most likely binds glucose phosphates very much the same as AGPases thymidilyltransferases arent governed allosterically. Both HA14-1 AGPase crystal buildings claim that the enzyme features being a dimer of dimers like the system suggested for the enzyme based on ligand-binding research (Haugen and Preiss 1979 All obtainable evidence network marketing leads to the final outcome that tetramers are necessary for AGPase catalytic activity. Both obtainable AGPase crystal buildings present two ...

Two absolutely conserved histidines and a third highly conserved histidine are noted in 11 bacterial and plant ADP-glucose pyrophosphorylases. These histidines were individually mutagenized in the E. coli enzyme to glutamine in order to determine their function. Glutamine mutations at residues 143 and 156 produced functional enzymes in cell extracts with slightly lower than wild-type specific catalytic activities and with same heat stability characteristics of the wild-type enzyme. Substitution of residue 83 with glutamine however produced an enzyme having decreased thermal stability. Additional mutageneses at residue 83 with asparagine, arginine, or aspartate gave rise to enzymes having a progressively decreasing trend in thermal stability. These mutants are more susceptible to proteolysis than wild-type enzyme. Kinetic analysis of H83Q and H83N indicates that histidine 83 is not involved in the catalytic mechanism or in substrate binding but possibly in maintenance of the active catalytic structure.

Different studies concerning starch metabolism in potato and tomato have suggested that AGPase activity plays an important role in regulation (Geigenberger et al., 1999; Sweetlove et al., 1999; Geigenberger, 2011). AGPase activity is known to be modulated via several different mechanisms. AGPase is sensitive to allosteric regulation, being inhibited by inorganic phosphate and activated by 3-phosphoglycerate (3PGA; Sowokinos, 1981; Sowokinos and Preiss, 1982). Additionally, it has been demonstrated to be transcriptionally regulated by sugars, nitrate, phosphate, and trehalose-6-phosphate (Müller-Röber et al., 1990; Nielsen et al., 1998; Kolbe et al., 2005; Michalska et al., 2009). Moreover, it has been described that AGPase is also redox regulated (Tiessen et al., 2002; Centeno et al., 2011), with malic acid potentially being a key component in this process at least in photosynthetically active tissues (Szecowka et al., 2012).. In tomato, as previously mentioned, a differential regulation of ...

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The resulting altered UMP ratio indirectly influences starch biosynthesis. In wild-type plants, a portion of the cellular glucose-1-phosphate is not used for starch biosynthesis but is converted to sucrose with the help of UDP-glucose-pyrophosphorylase (UGPase) and sucrose synthase. UGPase needs UTP for the synthesis of UDP-glucose. The reduced de novo synthesis of UMP would, by extension, lead to a reduced UTP content and therfore prevent the reconversion of glucose-1-phosphate to sucrose. More glucose-1-phosphate will, therefore, be available for starch biosynthesis, resulting in a 10-20% increase in tuber weight maintaining a constant density ...

The entry of carbon from sucrose into cellular metabolism in plants can potentially be catalyzed by either sucrose synthase (SUS) or invertase (INV).

Preiss, A., & Krauter, S. (2010). Performance comparison of a-Si, μ-Si, and c-Si as a function of air mass and turbidity. . In Proceedings of the 25th European Photovoltaic Solar Energy Conference and Exhibition, Valencia (Spanien), September 6-10,2010 ...

Po dveh letih je znova izšla revija Zdrava zabava. V njej najdete veliko zanimivih vsebin, zgodb, rezultatov in celoten prerez dogajanja na SUS...

Kernels of wild-type maize (Zea mays L.) shrunken-1 (sh1), deficient in the predominant form of endosperm sucrose synthase and shrunken-2 (sh2), deficient in 95% of the endosperm ADP-glucose pyrophosphorylase were grown in culture on sucrose, glucose, or fructose as the carbon source. Analysis of the endosperm extracts by gas-liquid chromatography revealed that sucrose was present in the endosperms of all genotypes, regardless of carbon supply, indicating that all three genotypes are capable of synthesizing sucrose from reducing sugars. The finding that sucrose was present in sh1 kernels grown on reducing sugars is evidence that shrunken-1 encoded sucrose synthase is not necessary for sucrose synthesis. Shrunken-1 kernels developed to maturity and produced viable seeds on all carbon sources, but unlike wild-type and sh2 kernels grown in vitro, sucrose was not the superior carbon source. This latter result provides further evidence that the role of sucrose synthase in maize endosperm is primarily ...