Rubrobacter xylanophilus is a thermophilic species of bacteria. It is slightly halotolerant, short rod- and coccus-shaped and gram-positive, with type strain PRD-1T. It is the only true radiation resistant thermopile. It can degrade xylan and hemicellulose. The first strain of the genus Rubrobacter was isolated from gamma-irradiated hot spring water samples by Yoshinaka. This organism was found to be extremely gamma-radiation resistant, with a higher shoulder dose than the canonical radiation resistant species of the genus Deinococcus. The organism stained Gram-positive and was slightly thermophilic with an optimum growth temperature of about 45°C. Carreto, L.; Moore, E.; Nobre, M. F.; Wait, R.; Riley, P. W.; Sharp, R. J.; Da Costa, M. S. (1996). Rubrobacter xylanophilus sp. nov., a New Thermophilic Species Isolated from a Thermally Polluted Effluent. International Journal of Systematic Bacteriology. 46 (2): 460-465. doi:10.1099/00207713-46-2-460. ISSN 0020-7713. Home - Rubrobacter ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Marine-derived Actinobacteria are a source of a broad variety of secondary metabolites with diverse biological activities, such as antibiotics and antitumorals; many of which have been developed for clinical use. Rare Actinobacteria represent an untapped source of new bioactive compounds that have been scarcely recognized. In this study, rare Actinobacteria from marine sediments were isolated from the Valparaíso bay, Chile, and their potential to produce antibacterial compounds was evaluated. Different culture conditions and selective media that select the growth of Actinobacteria were used leading to the isolation of 68 bacterial strains. Comparative analysis of the 16S rRNA gene sequences led to identifying isolates that belong to the phylum Actinobacteria with genetic affiliations to 17 genera: Aeromicrobium, Agrococcus, Arthrobacter, Brachybacterium, Corynebacterium, Dietzia, Flaviflexus, Gordonia, Isoptericola, Janibacter, Microbacterium, Mycobacterium, Ornithinimicrobium, Pseudonocardia,
The taxonomic composition of picoplankton communities profoundly differs in freshwater and marine systems. Cultivation-independent molecular approaches have demonstrated that bacteria from large phylogenetic lineages of typical freshwater microbes, e.g., the β-subdivision of the proteobacteria, are virtually absent in the marine picoplankton (15, 23). For other bacterial lineages the evidence is less conclusive. Comparative analysis of 16S rDNA genes indicate that uncultured members of the class Actinobacteria are ubiquitous in lakes of various trophic state, size or geographic location (16, 36), but actinobacterial sequence types are also known from marine systems (31).. A direct microscopic visualization of freshwater Bacteria by fluorescence in situ hybridization (FISH) with rRNA-targeted oligonucleotide probes is still difficult, and frequently only a low fraction of all picoplankton cells (,50%) can be visualized by FISH (5, 10, 15, 19). We hypothesize that this may be due to high ...
Bacterial genome sequences consistently contain many more biosynthetic gene clusters encoding specialized metabolites than predicted by the compounds discovered from the respective strains. One hypothesis invoked to explain the cryptic nature of these gene clusters is that standard laboratory conditions do not provide the environmental cues needed to trigger gene expression. A potential source of such cues is other members of the bacterial community, which are logical targets for competitive interactions. In this study, we examined the effects of such interactions on specialized metabolism in the marine actinomycete Salinispora tropica. The results show that antibiotic activities and the concentration of some small molecules increase in the presence of co-occurring bacterial strains relative to monocultures. Some increases in antibiotic activity could be linked to nutrient depletion by the competitor as opposed to the production of a chemical cue. Other increases were correlated with the production of
Eggerthella lenta is an anaerobic, non-sporulating, gram positive bacillus in the Coriobacteriaceae family. The aim of this study was to describe the clinical features of the authors cases of E. Lenta bacteraemia, and further define their microbiological characteristics using modern microbiological techniques.
Most Actinobacteria of medical or economic significance are in subclass Actinobacteridae, and belong to the order Actinomycetales. While many of these cause disease in humans, Streptomyces is notable as a source of antibiotics. Of those Actinobacteria not in the Actinomycetales, Gardnerella is one of the most researched. Classification of Gardnerella is controversial, and MeSH catalogues it as both a Gram-positive and Gram-negative organism.[9]. Actinobacteria, especially Streptomyces spp., are recognized as the producers of many bioactive metabolites that are useful to humans in medicine, such as antibacterials,[10] antifungals,[11] antivirals, antithrombotics, immunomodifiers, antitumor drugs, and enzyme inhibitors; and in agriculture, including insecticides, herbicides, fungicides, and growth-promoting substances for plants and animals.[12][13] Actinobacteria-derived antibiotics that are important in medicine include aminoglycosides, anthracyclines, chloramphenicol, macrolide, tetracyclines, ...
Extreme and unusual ecosystems such as isolated ancient caves are considered as potential tools for the discovery of novel natural products with biological activities. Actinobacteria that inhabit these unusual ecosystems are examined as a promising source for the development of new drugs. In this study we focused on the preliminary estimation of fatty acid composition and antibacterial properties of culturable actinobacteria isolated from water surface of underground lakes located in Badzheyskaya and Okhotnichya caves in Siberia. Here we present isolation of 17 strains of actinobacteria that belong to the Streptomyces, Nocardia and Nocardiopsis genera. Using assays for antibacterial and antifungal activities, we found that a number of strains belonging to the genus Streptomyces isolated from Badzheyskaya cave demonstrated inhibition activity against bacteria and fungi. It was shown that representatives of the genera Nocardia and Nocardiopsis isolated from Okhotnichya cave did not demonstrate any tested
Eggerthella lenta ATCC ® 43055™ Designation: MSMC 77-67 TypeStrain=False Application: Quality control strain Susceptibility testing
Eggerthella lenta ATCC ® 43055™ Designation: MSMC 77-67 TypeStrain=False Application: Quality control strain Susceptibility testing
ID A0A0J0UT43_9ACTN Unreviewed; 433 AA. AC A0A0J0UT43; DT 14-OCT-2015, integrated into UniProtKB/TrEMBL. DT 14-OCT-2015, sequence version 1. DT 22-NOV-2017, entry version 10. DE RecName: Full=M18 family aminopeptidase {ECO:0000256,RuleBase:RU004387}; DE EC=3.4.11.- {ECO:0000256,RuleBase:RU004387}; GN ORFNames=IMCC26207_110292 {ECO:0000313,EMBL:KLR60046.1}; OS Actinobacteria bacterium IMCC26207. OC Bacteria; Actinobacteria. OX NCBI_TaxID=1641811 {ECO:0000313,EMBL:KLR60046.1, ECO:0000313,Proteomes:UP000036180}; RN [1] {ECO:0000313,EMBL:KLR60046.1, ECO:0000313,Proteomes:UP000036180} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=IMCC26207 {ECO:0000313,EMBL:KLR60046.1, RC ECO:0000313,Proteomes:UP000036180}; RA Kim S., Cho J.-C.; RT Genome sequence of freshwater Actinobacteria.; RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases. CC -!- COFACTOR: CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105; CC Evidence={ECO:0000256,RuleBase:RU004387}; CC -!- SIMILARITY: Belongs to the peptidase M18 ...
Summary: A 16S rRNA-based molecular ecological study was performed to search for dominant bacterial sequences in Drentse A grassland soils (The Netherlands). In the first step, a library of 165 clones was generated from PCR-amplified 16S rDNA. By sequence comparison, clone DA079 and two other identical clones could be affiliated to a group of recently described uncultured Actinobacteria. This group contained 16S rDNA clone sequences obtained from different environments across the world. To determine whether such uncultured organisms were part of the physiologically active population in the soil, ribosomes were isolated from the environment and 16S rRNA was partially amplified via RT-PCR using conserved primers for members of the domain Bacteria. Subsequent sequence-specific separation by temperature-gradient gel electrophoresis (TGGE) generated fingerprints of the amplicons. Such community fingerprints were compared with the TGGE pattern of PCR-amplified rDNA of clone DA079 which was generated with the
Valid publication: DEWHIRST (F.E.), PASTER (B.J.), TZELLAS (N.), COLEMAN (B.), DOWNES (J.), SPRATT (D.A.) and WADE (W.G.): Characterization of novel human oral isolates and cloned 16S rDNA sequences that fall in the family Coriobacteriaceae: description of Olsenella gen. nov., reclassification of Lactobacillus uli as Olsenella uli comb. nov. and description of Olsenella profusa sp. nov. Int. J. Syst. Evol. Microbiol., 2001, 51, 1797-1804 ...
Acidimicrobium ferrooxidans gen. nov., sp. nov.: mixed-culture ferrous iron oxidation with Sulfobacillus species. Microbiology, 1996, 142, 785-790 ...
Actinomycetes are the most profitable and biotechnologically valued prokaryotes representing the genera consisting of Streptomyces, Arthrobacter, Actinomyces, Cornyebacterium, Micrococcus, Micromonospora and other diverse species of microorganisms. Actinomycetes represent a group of one of the most powerful secondary metabolite producers which possess a wide range of biological activities. Streptomyces, an important genus under actinomycetes, alone serves as the huge producer of a number of biologically active molecules. This genus possesses a huge potential of synthesizing various different and novel active metabolites. Due to the gradual reduction of the chances of isolation of novel compounds within Streptomyces coming from terrestrial environs resulting in the increase of resistant pathogenic microorganisms, marine actinomycetesmay form a platform for novel drug synthesis, which in-turn may form an extraordinary tool for combating a wide range of resistant microbes. The role of marine ...
ID A0A076MGV6_AMYME Unreviewed; 538 AA. AC A0A076MGV6; DT 29-OCT-2014, integrated into UniProtKB/TrEMBL. DT 29-OCT-2014, sequence version 1. DT 25-OCT-2017, entry version 27. DE RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256,HAMAP-Rule:MF_00377, ECO:0000256,RuleBase:RU000577}; GN Name=dnaA {ECO:0000256,HAMAP-Rule:MF_00377, GN ECO:0000313,EMBL:AIJ20093.1}; GN ORFNames=AMETH_0001 {ECO:0000313,EMBL:AIJ20093.1}; OS Amycolatopsis methanolica 239. OC Bacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae; OC Amycolatopsis. OX NCBI_TaxID=1068978 {ECO:0000313,EMBL:AIJ20093.1, ECO:0000313,Proteomes:UP000062973}; RN [1] {ECO:0000313,EMBL:AIJ20093.1, ECO:0000313,Proteomes:UP000062973} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=239 {ECO:0000313,EMBL:AIJ20093.1, RC ECO:0000313,Proteomes:UP000062973}; RA Tang B.; RT Whole Genome Sequence of the Amycolatopsis methanolica 239.; RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: ...
TY - JOUR. T1 - Regulation of specialised metabolites in Actinobacteria - expanding the paradigms. AU - Hoskisson, Paul A. AU - Fernández-Martínez, Lorena T.. N1 - © 2018 Society for Applied Microbiology and John Wiley & Sons Ltd.. PY - 2018/4/6. Y1 - 2018/4/6. N2 - The increase in availability of actinobacterial whole genome sequences has revealed huge numbers of specialised metabolite biosynthetic gene clusters, encoding a range of bioactive molecules such as antibiotics, antifungals, immunosuppressives and anticancer agents. Yet the majority of these clusters are not expressed under standard laboratory conditions in rich media conditions. Emerging data from studies of specialised metabolite biosynthesis suggest that the diversity of regulatory mechanisms is greater than previously thought and these act at multiple levels, through a range of signals such as nutrient limitation, intercellular signalling and competition with other organisms. Understanding the regulation and environmental cues ...
The Antarctic represents a largely untapped source for isolation of new microorganisms with potential to produce bioactive natural products. Actinomycetes are of special interest among such microorganisms as they are known to produce a large number of natural products, many of which have clinical, pharmaceutical or agricultural applications. We isolated, characterized and classified actinomycetes from soil samples collected from different locations on Signy Island, South Orkney Islands, in the maritime Antarctic. A total of 95 putative actinomycete strains were isolated from eight soil samples using eight types of selective isolation media. The strains were dereplicated into 16 groups based on morphology and Amplified Ribosomal DNA Restriction Analysis (ARDRA) patterns. Analysis of 16S rRNA gene sequences of representatives from each group showed that streptomycetes were the dominant actinomycetes isolated from these soils; however, there were also several strains belonging to diverse and rare ...
Actinomycetes also refers as filamentous Actinobacteria and acts as a connecting link between the bacteria and fungi as it shows resemblance with both. In this article, definition, characteristics, classification and economic importance of Actinomycetes are explained.
Secondary metabolites produced by Actinobacteria of tropical soils represent a largely understudied source of novel molecules with relevant applicatio..
Taxonomic hierarchy of Subdivision Actinobacteria Cavalier-Smith 2002. Display of synonyms, alternative taxonomic positions, references, number of subtaxa, and phylogenetic/bibliographic position can be switched on/off. Subtaxa can be ordered by name or phylogenetic/bibliographic position.
Read Plant Growth Promoting Actinobacteria A New Avenue for Enhancing the Productivity and Soil Fertility of Grain Legumes by with Rakuten Kobo. Global yields of legumes have been relatively stagnant for the last five decades, despite the adoption of conventional a...
Fingerprint Dive into the research topics of Detection and molecular characterization of filamentous actinobacteria and thermoactinomycetes present in water-damaged building materials. Together they form a unique fingerprint. ...
Sigma-Aldrich offers abstracts and full-text articles by [Feng Xie, Shengwang Dai, Jinzhao Shen, Biao Ren, Pei Huang, Qiushui Wang, Xueting Liu, Buchang Zhang, Huanqin Dai, Lixin Zhang].
Other Names: Actinobacteria Actinobacteria Stackebrandt et al. 1997 Actinobacteria Stackebrandt et al. 1997 emend. Nouioui et al. 2018 Actinobacteridae Actinobacteridae Stackebrandt et al. 1997 emend. Zhi et al. 2009 Actinomycetes Actinomycetes Krasilnikov 1949 high G+C Gram-positive bacteria high GC Gram+ High GC gram-positive bacteria Change Display Name to ...
Lineage: cellular organisms; Bacteria; Terrabacteria group; Actinobacteria; Actinobacteria; Bifidobacteriales; Bifidobacteriaceae; ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Actinomycetes are interesting as a main producer of secondary metabolites and industrial antibiotics from marine environments. A total of 44 strains of actinomycetes were isolated from Caspian Sea sediments at a depth of 5-10 m. Preliminary screening was done using cross-streak method against 2 gram-positive and 4 gram-negative pathogen bacteria. The most potent strains MN2, ...
RN [1] RM PMID:20675471 RT Unexpected abundance of coenzyme F(420)-dependent enzymes in Mycobacterium tuberculosis and other actinobacteria. RA Selengut JD, Haft DH RL J Bacteriol. 2010 Nov;192(21):5788-98. RN [2] RM PMID:16930487 RT Exopolysaccharide-associated protein sorting in environmental organisms: the PEP-CTERM/EpsH system. Application of a novel phylogenetic profiling heuristic. RA Haft DH, Paulsen IT, Ward N, Selengut JD RL BMC Biol. 2006 Aug 24;4:29 ...
Actinomycetes are gram-positive, free-living, saprophytic bacteria widely distributed in soil, water and colonizing plants showing marked chemical and morphological diversity. They are potential source of many bioactive compounds, which have diverse clinical effects and important applications in human medicine. In the present work, we have studied some of the physiological and biochemical characteristics of 36 actinomycete strains isolated from the shola soils of tropical montane forest; a relatively unexplored biodiversity hotspot. Ability of actinomycetes isolates to ferment and produce acids from various carbohydrate sources such as innositol, mannose, sorbitol, galactose, mannitol, xylose, rhamnose, arabinose, lactose and fructose were studied. Almost all the carbon compounds were utilized by one or other actinomycete isolates. The most preferred carbon sources were found to be xylose (94.44%) followed by fructose and mannose (91.66%). Only 41.76% of the isolates were able to ferment ...
Abstract: Actinomycetes are one of the most important groups that produce useful secondary metabolites. They play a great role in pharmaceutical and industrial uses. The search for antibiotic producing soil actinomycetes to inhibit the growth of pathogenic microorganisms has become widespread due to the need for newer antibiotics. The present work was aimed to isolate soil actinomycetes from pinus tree rhizosphere from Doddabetta, Western Ghats, Tamil Nadu, India. Thirty one actinomycetes were isolated based on heterogeneity and stability in subculturing; they were screened against 5 Gram positive and 7 Gram negative bacteria in an in vitro antagonism assay. In the preliminary screening, out of 31 isolates, 12.09% showed good antagonistic activity; 25.08% showed moderate activity; 19.35% showed weak activity and 41.93% showed no activity against the tested bacteria. Among the isolates tested, DPR20 showed good antibacterial activity against both Gram positive and Gram negative bacteria. The ...
DI-fusion, le Dépôt institutionnel numérique de lULB, est loutil de référencementde la production scientifique de lULB.Linterface de recherche DI-fusion permet de consulter les publications des chercheurs de lULB et les thèses qui y ont été défendues.
This chapter discusses some of the stressors likely to target the cell envelope of Mycobacterium tuberculosis during infection, and the corresponding regulatory elements expressed by the bacterium to counteract this stress. Phylogenetically, M. tuberculosis is a member of the phylum Actinobacteria, which also includes several notable human pathogens, including species of the genera Streptomyces, Corynebacterium, Nocardia, and Rhodococcus. M. tuberculosis is a facultative intracellular pathogen, and its host range is restricted to humans. The bacterium is not normally found free within the environment, so its continued survival within the human population requires that it be transmitted directly from an infected individual with active disease to one that is susceptible to infection. Posttranslational phosphorylation of proteins was traditionally thought to be limited to eukaryotic cells. However, the discovery of two-component signal transduction systems (TCSSs) in bacteria shifted this paradigm to
The composting process is a complex interaction between the waste and the microorganisms within the waste. The microorganisms that carry out this process fall into three groups: bacteria, fungi, and actinomycetes. Actinomycetes are a form of fungi-like bacteria that break down organic matter. The first stage of the biological activity is the consumption of easily available sugars by […]. ...
The composting process is a complex interaction between the waste and the microorganisms within the waste. The microorganisms that carry out this process fall into three groups: bacteria, fungi, and actinomycetes. Actinomycetes are a form of fungi-like bacteria that break down organic matter. The first stage of the biological activity is the consumption of easily available sugars by […]. ...
A new hierarchic classification structure for the taxa between the taxonomic levels of genus and class is Proposed for the actinomycete line of descent as defined by analysis of small subunit (16S) rRNA and genes coding for this molecule (rDNA). While the traditional circumscription of a genus of the actinomycete subphylum is by and large in accord with the 16S rRNA/rDNA-based phylogenetic clustering of these organisms. most of the higher taxa proposed in the past do not take into account the phylogenetic clustering of genera. The rich chemical, morphological and physiological diversity of phylogenetically closely related genera makes the description of families and higher taxa so broad that they become meaningless for the description of the enclosed taxa. Here we present a classification system in which phylogenetically neighboring taxa at the genus level are clustered into families, suborders, orders, subclasses, and a class irrespective of those phenotypec characteristics on which the delineation of
Lineage: cellular organisms; Bacteria; Terrabacteria group; Actinobacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae; Amycolatopsis; Amycolatopsis ...
For a comprehensive guide to actinomycete characterisation see the Compendium of Actinobacteria from Prof. Joachim Wink at the German Collection of Microorganisms & Cell Cultures (DSMZ). This resouce provides protocols for characterising a wide range of features for new isolates, but may also be applicable more broadly for example for phenotyping experiments. The tests include colony morphology, melanin production, salt tolerance, carbon utlilisation and much more. To download the guide please see the link below. DSMZ Compendium of Actinobacteria ...
Methodology/Principal Findings: Here, we report molecular monitoring of the stone-autochthonous microbiota before and at 5, 12 and 30 months after the bio-consolidation treatment (medium/long-term monitoring), employing the well-known molecular strategy of DGGE analyses. Before the bio-consolidation treatment, the bacterial diversity showed the exclusive dominance of Actinobacteria (100%), which decreased in the community (44.2%) after 5 months, and Gamma-proteobacteria (30.24%) and Chloroflexi (25.56%) appeared. After 12 months, Gamma-proteobacteria vanished from the community and Cyanobacteria (22.1%) appeared and remained dominant after thirty months, when the microbiota consisted of Actinobacteria (42.2%) and Cyanobacteria (57.8%) only. Fungal diversity showed that the Ascomycota phylum was dominant before treatment (100%), while, after five months, Basidiomycota (6.38%) appeared on the stone, and vanished again after twelve months. Thirty months after the treatment, the fungal population ...
Atopobium vaginae is a species of bacteria in the genus of Actinobacteria, in the family Coriobacteriaceae. It is a facultative anaerobic, Gram-positive rod-shaped or elliptical coccobacilli found as single elements or in pairs or short chains. It is typically isolated from 80% of women with bacterial vaginosis and it is implicated in treatment failures. Jovita, M. R.; Collins, M. D.; Sjoden, B.; Falsen, E. (1999). Characterization of a novel Atopobium isolate from the human vagina: description of Atopobium vaginae sp. nov. International Journal of Systematic Bacteriology. 49 (4): 1573-1576. doi:10.1099/00207713-49-4-1573. ISSN 0020-7713. PMID 10555338. Mastromarino, Paola; Vitali, Beatrice; Mosca, Luciana (2013). Bacterial vaginosis: a review on clinical trials with probiotics (PDF). New Microbiologica. 36: 229-238. PMID 23912864. Polatti, Franco (2012). Bacterial Vaginosis, Atopobium vaginae and Nifuratel. Current Clinical Pharmacology. 7 (1): 36-40. doi:10.2174/157488412799218824. ISSN ...
A taxonomic study was carried out to clarify the taxonomy of representatives of a group of marine actinomycetes previously designated MAR 1 and considered to belong to the family Micromonosporaceae. The organisms had phenotypic properties consistent with their assignment to this taxon. The strains formed a distinct taxon in the 16S rRNA Micromonosporaceae gene tree and shared a range of phenotypic properties that distinguished them from members of all of the genera with validly published names classified in this family. The name proposed for this novel taxon is Salinispora gen. nov. The genus contains two species recognized using a range of genotypic and phenotypic criteria, including comparative 16S-23S rRNA gene spacer region and DNA-DNA relatedness data. The names proposed for these taxa are Salinispora arenicola sp. nov., the type species, and Salinispora tropica sp. nov.; the type strains of these novel species have been deposited in service culture collections as strain CNH-643T (=ATCC BAA-917T
Looking for online definition of Actinobacteria in the Medical Dictionary? Actinobacteria explanation free. What is Actinobacteria? Meaning of Actinobacteria medical term. What does Actinobacteria mean?
Bioprospecting natural products in marine bacteria from fjord environments are attractive due to their unique geographical features. Although, Actinobacteria are well known for producing a myriad of bioactive compounds, investigations regarding fjord derived marine Actinobacteria are scarce. In this study, the diversity and biotechnological potential of Actinobacteria isolated from marine sediments within the Comau fjord, in Northern Chilean Patagonia, were assessed by culture-based approaches. The 16S rRNA gene sequences revealed that members phylogenetically related to the Micrococcaceae, Derrnabacteraceae. Brevibacteriaceae, Corynebacteriaceae. Microbacteriaceae, Dietziaceae, Nocardiaceae, and Streptomycetaceae families were present at the Comau fjord. A high diversity of cultivable Actinobacteria (10 genera) was retrieved by using only five different isolation media. Four isolates belonging to Arthrobacter, Brevibacterium, Corynebacterium and Kocuria genera showed 16S rRNA gene identity ...
International Journal of Evolutionary Biology is a peer-reviewed, Open Access journal that publishes original research articles as well as review articles in all areas of evolutionary biology.
Colin A. B. Davidson ,cabd2 at hermes.cam.ac.uk, wrote in message news:,9n500j$4hn$1 at pegasus.csx.cam.ac.uk,... , Daniel B. Wheeler ,dwheeler at ipns.com, wrote in message , news:6dafee1b.0109010714.23c083f0 at posting.google.com... , (CUT) , , BTW, the above total may sound overestimated by some. But when such , , things as rusts, smuts, ectomycorrhizae, endomycorrhizae, soil, and , , compost actinomycetes are added, , , Whoah there! , , Sorry to seem a pedant, but the actinomycetes are bacteria, not fungi :-) Ill take your word for it Colin. I have not studied the actinomycetes yet. But they sure sound similar to basidiomycetes and ascomycetes. Then, of course, theres the Termite mushrooms, Termitomyces... Sounds like the same to me. Of course, theres a lot of fungi I dont recognize yet. Thats what happens when you dont get a degree in mycology, I guess. , , ,it doesnt seem an overestimate (at , , least to me) at all. Then you have the newly discovered endophytic , , fungi, found ...
Similarly to their terrestrial relatives, marine microbes are a rich source of bioactive metabolites (antibiotics, antitumor drugs) and enzymes with different applications. For instance, cultivation of a marine actinomycete known as Salinispora tropica yielded a number of novel metabolites, not found before. One of these compounds, salinosporamide A, has antitumor properties and is currently being tested in humans for the treatment of cancer. Sequencing the genome of Salinispora tropica unveiled a number of genes coding for the synthesis of 17 potential metabolites; most of these compounds had not been detected in previous culturing of the microbe. Then, the researchers used the genetic information to guide a new chemical analysis of Salinispora cultures. The analysis uncovered an additional, novel compound (salinilactam), which had a structure corresponding to that deduced from the DNA sequence ...
Reference: EUZÉBY (J.P.) and TINDALL (B.J.): Nomenclatural type of orders: corrections necessary according to Rules 15 and 21a of the Bacteriological Code (1990 Revision) and designation of appropriate nomenclatural types of classes and subclasses. Request for an Opinion. Int. J. Syst. Evol. Microbiol. 2001, 51, 725-727 ...
Research in my laboratory is focused on understanding the production of natural products from Actinomycetes. Actinomycetes are a wonderful and diverse group of gram positive bacteria present in almost all environments. In particular my research group is interested in the genus Streptomyces because this genus alone is responsible for the production of a high number of clinically relevant specialised metabolites including antibiotics, anti-fungal, antihelminthic and anti-cancer drugs.. By understanding how these medically relevant compounds are made by the producing organism, we can manipulate these biosynthetic pathways and therefore increase their yield. This is essential for industry as in order to undergo clinical trials, biotechnology companies need to be able to obtain high quantities of the purified new drug to be tested.. We also have an interest on how these industrially relevant Streptomyces strains develop in their natural environment. Streptomyces contain an arsenal of specialised ...
In the era where large whole genome bacterial data sets are generated routinely, rapid and accurate molecular systematics is becoming increasingly important. However, 16S ribosomal RNA sequencing does not always offer sufficient resolution to discriminate between closely related genera. The SsgA-like proteins (SALPs) are developmental regulatory proteins in sporulating actinomycete, whereby SsgB actively recruits FtsZ during sporulation-specific cell division. Here we present a novel method to classify actinomycetes, based on the extraordinary way the SsgA and SsgB proteins are conserved. The almost complete conservation of the SsgB amino acid sequence between members of the same genus, and its high divergence even between closely related genera, provides high quality data for the classification of morphologically complex actinomycetes. Our analysis validates Kitasatospora as a sister genus to Streptomyces in the family Streptomycetaceae and suggests that Micromonospora, Salinispora and ...
Bacteria necessitate multiple signal transduction systems to sense the ever-changing environments and mediate the cellular response accordingly. The major bacterial signal transduction systems are one-component system (1CS), two-component system (2CS) and extracytoplasmic function (ECF) σ factor. Compared to 1CSs and 2CSs, ECF σ factors have only been identified much later and therefore the knowledge about their molecular mechanisms and physiological roles is less profound. This thesis mainly focuses on the study of ECF σ factors from the bacterial phyla, Planctomycetes and Actinobacteria., In the first two parts of this study, ECF σ factors from eight planctomycetal genomes and 119 actinobacterial genomes were classified and analyzed in depth. This led to the identification of eight novel ECF groups consisting of 202 protein members from Planctomycetes and 18 novel ECF groups consisting of 427 protein members from Actinobacteria, respectively. Many of these novel ECF groups were found to ...
Construction of a D-valine sensor using D-amino acid oxidase of Rubrobacter xylanophilus, Journal of Technology and Education, 2016/12/01, Katsumi TAKAYAMA, Chisato SAKAMOTO, Shouji TAKAHASHI, Katsumasa ABE, Ayano HIROBE, and Takeji KOSHIGIRI. ...
Researchers found that there was no significant difference between groups for body weight gain, overall caloric intake, body fat, lean mass, or overall adiposity index. Rats that consumed sugar water consumed less of the solid food. As a result of this well-established compensatory behavior in Sprague-Dawley rats, all three sugar groups consumed a significantly lower percentage of energy from fat and protein compared to the control.. The 16s rRNA sequencing of fecal samples taken at post-natal day 80 revealed a distinct clustering pattern when comparing the sugar to non-sugar fed rats. Interestingly, when comparing the 3 different fructose-to-glucose ratio groups, there was no distinct clustering pattern observed. Researchers detail a number of shifts in the microbiome at the phylum, class, order, family, and genus level. For example, at the phylum level, Proteobacteria and Actinobacteria were elevated in the sugar consuming groups. At the class level, Actinobacteria, Bacilli, Alpha-, Beta- and ...
Proteome IDi ,p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the ,a href=http://www.uniprot.org/manual/proteomes_manual>proteome,/a>. It consists of the characters UP followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.,p>,a href=/help/proteome_id target=_top>More...,/a>,/p> ...
Proteome IDi ,p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the ,a href=http://www.uniprot.org/manual/proteomes_manual>proteome,/a>. It consists of the characters UP followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.,p>,a href=/help/proteome_id target=_top>More...,/a>,/p> ...
The gut microbiome uses a number of diverse mechanisms to alter the disposition, efficacy and toxicity of drugs and xenobiotics as follows (Carmody and Turnbaugh, 2014; Klaassen and Cui, 2015): 1) The gut microbiota may express enzymes that either metabolically activate or inactivate drugs. For example, sulfalazine used to treat gut inflammation is converted to its pharmacologically active form, 5-amino 5-salicylic acid by microbial enzymes. In contrast, digoxin is inactivated by a cardiac glycoside expressed by Eggerthella lenta. 2) The drug may be sequestered by direct binding to the bacterial organism. An example here is the sequestration of L-DOPA by Helicobacter pylori. 3) The drug may be metabolically reactivated by microbially expressed enzymes. A good example of this mechanism is provided by the chemotherapeutic drug irinotecan (also called CPT-11) (Wallace et al., 2010). In the liver, irinotecan is metabolically inactivated via glucuronidation. Within the intestines, however, it is ...
This site is maintained by SARE Outreach for the SARE program and is based upon work supported by the National Institute of Food and Agriculture, U.S. Department of Agriculture, under award No. 2019-38640-29881. SARE Outreach operates under cooperative agreements with the University of Maryland to develop and disseminate information about sustainable agriculture. USDA is an equal opportunity provider and employer.. ...
This site is maintained by SARE Outreach for the SARE program and is based upon work supported by the National Institute of Food and Agriculture, U.S. Department of Agriculture, under award No. 2019-38640-29881. SARE Outreach operates under cooperative agreements with the University of Maryland to develop and disseminate information about sustainable agriculture. USDA is an equal opportunity provider and employer.. ...
Recently Mycobacterium tuberculosis was shown to possess a novel protein modification, in which a small protein Pup is conjugated to the epsilon-amino groups of lysines in target proteins. Analogous to ubiquitin modification in eukaryotes, this remarkable modification recruits proteins for degradation via archaeal-type proteasomes found in mycobacteria and allied actinobacteria. While a mycobacterial protein named PafA was found to be required for this conjugation reaction, its biochemical mechanism has not been elucidated. Using sensitive sequence profile comparison methods we establish that the PafA family proteins are related to the γ-glutamyl-cysteine synthetase and glutamine synthetase. Hence, we predict that PafA is the Pup ligase, which catalyzes the ATP-dependent ligation of the terminal γ-carboxylate of glutamate to lysines, similar to the above enzymes. We further discovered that an ortholog of the eukaryotic PAC2 (e.g. cg2106) is often present in the vicinity of the actinobacterial Pup
BIOMEDICUS GEL CU SARE DE BAZNA 250 ML gel cu sare de bazna , extract de tataneasa , scoarta de salcie , brusture si salvie.   Sarea de bazna - este extrasa de la mare adancime din subsolul satiunii Bazna, jud.Mures. Sarea este obtinuta prin fierbarea si evaporarea apelor minerale bogate in cloruri de natriu,potasiu,magneziu, calciu iodura de brom si de natriu. Sarea de bazna este indicata in: reumatism, artorza , poliartrita, discopatii, mialgii, hipertiroidie, leucoplazie. Tataneasa extern este considerata un adevarat panaceu, deoarece alina inflamatiile si grabeste vindecarea in dermatoze, inchide si vindeca rapid plagile,grabeste procesul de refacere a epidermei dupa arsuri, face sa se retraga tumorile exteriorizate, reface rapid tesuturile dupa contuzii si traumatisme. Unul din cele mai active principii ale tatanesei este alantoina, avand efecte antiinflamatoare, antitumorale si favorizeaza refacerea tesuturilor. Extractul de scoarta de Salcie , aspirina naturala
A division of the Bacteria (Eubacteria) that has three classes, the anaerobic Clostridia, the aerobic Bacilli, and the Mollicutes (mycoplasmas). They differ from Actinobacteria in having low G+C levels in their DNA. Most, but not all, are Gram-positive. ...
A few Firmicutes encode a fusion between accD and accA (CLOTE, EUBR3, FRAAA, FRACC, FRASN, NATTJ) as do a few Actinobacteria (SACEN, SALAI and SALTO). Most plants have 2 forms, the so-called prokaryotic form in their plastids and the eukaryotic form in the cytoplasm. The prokaryotic form is longer than the one found in bacteria. The grass family (Poaceae) have only the eukaryotic form in both locations. The eukaryotic form consists of a single large protein in which are fused all 4 subunits that are separate in prokaryotes ...
Exploiting the genomes of the Actinobacteria: plant growth promoters and producers of natural products and energy relevant enzymes united in a taxonomically unresolved ...
ID CONWI_1_PE3285 STANDARD; PRT; 498 AA. AC CONWI_1_PE3285; D3FF04; DT 00-JAN-0000 (Rel. 1, Created) DT 00-JAN-0000 (Rel. 2, Last sequence update) DT 00-JAN-0000 (Rel. 3, Last annotation update) DE SubName: Full=Drug resistance transporter, EmrB/QacA subfamily; DE (CONWI_1.PE3285). GN OrderedLocusNames=Cwoe_3303; OS CONEXIBACTER WOESEI DSM 14684. OC Bacteria; Actinobacteria; Rubrobacteridae; Solirubrobacterales; OC Conexibacteraceae; Conexibacter. OX NCBI_TaxID=469383; RN [0] RP -.; RG -.; RL -.; CC -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CONWI_1.PE3285. CC Conexibacter woesei DSM 14684, complete genome. CC sequence. CC -!- ANNOTATIONS ORIGIN:D3FF04_CONWI CC -!- GENE_FAMILY: HOG000239124 [ FAMILY / ALN / TREE ] DR UniProtKB/Swiss-Prot; D3FF04; -. DR EMBL; CP001854; ADB51721.1; -; Genomic_DNA. DR RefSeq; YP_003395096.1; NC_013739.1. DR GeneID; 8733752; -. DR GenomeReviews; CP001854_GR; Cwoe_3303. DR KEGG; cwo:Cwoe_3303; -. DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. ...
Members of this protein family are Pup, a small protein whose ligation to target proteins steers them toward degradation. This protein family occurs in a number of bacteria, especially Actinobacteria such as Mycobacterium tuberculosis, that possess an archeal-type proteasome. All members of this protein family known during model construction end with the C-terminal motif [FY][VI]QKGG[QE]. Ligation is thought to occur between the C-terminal COOH of Pup and an epsilon-amino group of a Lys on the target protein. The N-terminal half of this protein is poorly conserved and not represented in the seed alignment ...
Buy A Classic Plain Red and Black Net Half N Half Sare online, SKU Code: SABS1711564. This Black color Party half n half saree for Women comes with Embroidered Net . Shop Now!
Occurrence of pppApp-synthesizing activity in actinomycetes and isolation of purine nucleotide pyrophosphotransferase.: The occurrence of adenosine 5-triphosph