Rubrobacter xylanophilus is a thermophilic species of bacteria. It is slightly halotolerant, short rod- and coccus-shaped and gram-positive, with type strain PRD-1T. It is the only true radiation resistant thermopile. It can degrade xylan and hemicellulose. The first strain of the genus Rubrobacter was isolated from gamma-irradiated hot spring water samples by Yoshinaka. This organism was found to be extremely gamma-radiation resistant, with a higher shoulder dose than the canonical radiation resistant species of the genus Deinococcus. The organism stained Gram-positive and was slightly thermophilic with an optimum growth temperature of about 45°C. Carreto, L.; Moore, E.; Nobre, M. F.; Wait, R.; Riley, P. W.; Sharp, R. J.; Da Costa, M. S. (1996). "Rubrobacter xylanophilus sp. nov., a New Thermophilic Species Isolated from a Thermally Polluted Effluent". International Journal of Systematic Bacteriology. 46 (2): 460-465. doi:10.1099/00207713-46-2-460. ISSN 0020-7713. Home - Rubrobacter ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Marine-derived Actinobacteria are a source of a broad variety of secondary metabolites with diverse biological activities, such as antibiotics and antitumorals; many of which have been developed for clinical use. Rare Actinobacteria represent an untapped source of new bioactive compounds that have been scarcely recognized. In this study, rare Actinobacteria from marine sediments were isolated from the Valparaíso bay, Chile, and their potential to produce antibacterial compounds was evaluated. Different culture conditions and selective media that select the growth of Actinobacteria were used leading to the isolation of 68 bacterial strains. Comparative analysis of the 16S rRNA gene sequences led to identifying isolates that belong to the phylum Actinobacteria with genetic affiliations to 17 genera: Aeromicrobium, Agrococcus, Arthrobacter, Brachybacterium, Corynebacterium, Dietzia, Flaviflexus, Gordonia, Isoptericola, Janibacter, Microbacterium, Mycobacterium, Ornithinimicrobium, Pseudonocardia,
The taxonomic composition of picoplankton communities profoundly differs in freshwater and marine systems. Cultivation-independent molecular approaches have demonstrated that bacteria from large phylogenetic lineages of typical freshwater microbes, e.g., the β-subdivision of the proteobacteria, are virtually absent in the marine picoplankton (15, 23). For other bacterial lineages the evidence is less conclusive. Comparative analysis of 16S rDNA genes indicate that uncultured members of the class Actinobacteria are ubiquitous in lakes of various trophic state, size or geographic location (16, 36), but actinobacterial sequence types are also known from marine systems (31).. A direct microscopic visualization of freshwater Bacteria by fluorescence in situ hybridization (FISH) with rRNA-targeted oligonucleotide probes is still difficult, and frequently only a low fraction of all picoplankton cells (,50%) can be visualized by FISH (5, 10, 15, 19). We hypothesize that this may be due to high ...
Eggerthella lenta is an anaerobic, non-sporulating, gram positive bacillus in the Coriobacteriaceae family. The aim of this study was to describe the clinical features of the authors cases of E. Lenta bacteraemia, and further define their microbiological characteristics using modern microbiological techniques.
Most Actinobacteria of medical or economic significance are in subclass Actinobacteridae, and belong to the order Actinomycetales. While many of these cause disease in humans, Streptomyces is notable as a source of antibiotics. Of those Actinobacteria not in the Actinomycetales, Gardnerella is one of the most researched. Classification of Gardnerella is controversial, and MeSH catalogues it as both a Gram-positive and Gram-negative organism.[9]. Actinobacteria, especially Streptomyces spp., are recognized as the producers of many bioactive metabolites that are useful to humans in medicine, such as antibacterials,[10] antifungals,[11] antivirals, antithrombotics, immunomodifiers, antitumor drugs, and enzyme inhibitors; and in agriculture, including insecticides, herbicides, fungicides, and growth-promoting substances for plants and animals.[12][13] Actinobacteria-derived antibiotics that are important in medicine include aminoglycosides, anthracyclines, chloramphenicol, macrolide, tetracyclines, ...
Extreme and unusual ecosystems such as isolated ancient caves are considered as potential tools for the discovery of novel natural products with biological activities. Actinobacteria that inhabit these unusual ecosystems are examined as a promising source for the development of new drugs. In this study we focused on the preliminary estimation of fatty acid composition and antibacterial properties of culturable actinobacteria isolated from water surface of underground lakes located in Badzheyskaya and Okhotnichya caves in Siberia. Here we present isolation of 17 strains of actinobacteria that belong to the Streptomyces, Nocardia and Nocardiopsis genera. Using assays for antibacterial and antifungal activities, we found that a number of strains belonging to the genus Streptomyces isolated from Badzheyskaya cave demonstrated inhibition activity against bacteria and fungi. It was shown that representatives of the genera Nocardia and Nocardiopsis isolated from Okhotnichya cave did not demonstrate any tested
Eggerthella lenta ATCC ® 43055™ Designation: MSMC 77-67 TypeStrain=False Application: Quality control strain Susceptibility testing
Eggerthella lenta ATCC ® 43055™ Designation: MSMC 77-67 TypeStrain=False Application: Quality control strain Susceptibility testing
ID A0A0J0UT43_9ACTN Unreviewed; 433 AA. AC A0A0J0UT43; DT 14-OCT-2015, integrated into UniProtKB/TrEMBL. DT 14-OCT-2015, sequence version 1. DT 22-NOV-2017, entry version 10. DE RecName: Full=M18 family aminopeptidase {ECO:0000256,RuleBase:RU004387}; DE EC=3.4.11.- {ECO:0000256,RuleBase:RU004387}; GN ORFNames=IMCC26207_110292 {ECO:0000313,EMBL:KLR60046.1}; OS Actinobacteria bacterium IMCC26207. OC Bacteria; Actinobacteria. OX NCBI_TaxID=1641811 {ECO:0000313,EMBL:KLR60046.1, ECO:0000313,Proteomes:UP000036180}; RN [1] {ECO:0000313,EMBL:KLR60046.1, ECO:0000313,Proteomes:UP000036180} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=IMCC26207 {ECO:0000313,EMBL:KLR60046.1, RC ECO:0000313,Proteomes:UP000036180}; RA Kim S., Cho J.-C.; RT "Genome sequence of freshwater Actinobacteria."; RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases. CC -!- COFACTOR: CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105; CC Evidence={ECO:0000256,RuleBase:RU004387}; CC -!- SIMILARITY: Belongs to the peptidase M18 ...
Valid publication: DEWHIRST (F.E.), PASTER (B.J.), TZELLAS (N.), COLEMAN (B.), DOWNES (J.), SPRATT (D.A.) and WADE (W.G.): Characterization of novel human oral isolates and cloned 16S rDNA sequences that fall in the family Coriobacteriaceae: description of Olsenella gen. nov., reclassification of Lactobacillus uli as Olsenella uli comb. nov. and description of Olsenella profusa sp. nov. Int. J. Syst. Evol. Microbiol., 2001, 51, 1797-1804 ...
Acidimicrobium ferrooxidans gen. nov., sp. nov.: mixed-culture ferrous iron oxidation with Sulfobacillus species. Microbiology, 1996, 142, 785-790 ...
ID A0A076MGV6_AMYME Unreviewed; 538 AA. AC A0A076MGV6; DT 29-OCT-2014, integrated into UniProtKB/TrEMBL. DT 29-OCT-2014, sequence version 1. DT 25-OCT-2017, entry version 27. DE RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256,HAMAP-Rule:MF_00377, ECO:0000256,RuleBase:RU000577}; GN Name=dnaA {ECO:0000256,HAMAP-Rule:MF_00377, GN ECO:0000313,EMBL:AIJ20093.1}; GN ORFNames=AMETH_0001 {ECO:0000313,EMBL:AIJ20093.1}; OS Amycolatopsis methanolica 239. OC Bacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae; OC Amycolatopsis. OX NCBI_TaxID=1068978 {ECO:0000313,EMBL:AIJ20093.1, ECO:0000313,Proteomes:UP000062973}; RN [1] {ECO:0000313,EMBL:AIJ20093.1, ECO:0000313,Proteomes:UP000062973} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=239 {ECO:0000313,EMBL:AIJ20093.1, RC ECO:0000313,Proteomes:UP000062973}; RA Tang B.; RT "Whole Genome Sequence of the Amycolatopsis methanolica 239."; RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: ...
TY - JOUR. T1 - Regulation of specialised metabolites in Actinobacteria - expanding the paradigms. AU - Hoskisson, Paul A. AU - Fernández-Martínez, Lorena T.. N1 - © 2018 Society for Applied Microbiology and John Wiley & Sons Ltd.. PY - 2018/4/6. Y1 - 2018/4/6. N2 - The increase in availability of actinobacterial whole genome sequences has revealed huge numbers of specialised metabolite biosynthetic gene clusters, encoding a range of bioactive molecules such as antibiotics, antifungals, immunosuppressives and anticancer agents. Yet the majority of these clusters are not expressed under standard laboratory conditions in rich media conditions. Emerging data from studies of specialised metabolite biosynthesis suggest that the diversity of regulatory mechanisms is greater than previously thought and these act at multiple levels, through a range of signals such as nutrient limitation, intercellular signalling and competition with other organisms. Understanding the regulation and environmental cues ...
The Antarctic represents a largely untapped source for isolation of new microorganisms with potential to produce bioactive natural products. Actinomycetes are of special interest among such microorganisms as they are known to produce a large number of natural products, many of which have clinical, pharmaceutical or agricultural applications. We isolated, characterized and classified actinomycetes from soil samples collected from different locations on Signy Island, South Orkney Islands, in the maritime Antarctic. A total of 95 putative actinomycete strains were isolated from eight soil samples using eight types of selective isolation media. The strains were dereplicated into 16 groups based on morphology and Amplified Ribosomal DNA Restriction Analysis (ARDRA) patterns. Analysis of 16S rRNA gene sequences of representatives from each group showed that streptomycetes were the dominant actinomycetes isolated from these soils; however, there were also several strains belonging to diverse and rare ...
Secondary metabolites produced by Actinobacteria of tropical soils represent a largely understudied source of novel molecules with relevant applicatio..
Taxonomic hierarchy of Subdivision Actinobacteria Cavalier-Smith 2002. Display of synonyms, alternative taxonomic positions, references, number of subtaxa, and phylogenetic/bibliographic position can be switched on/off. Subtaxa can be ordered by name or phylogenetic/bibliographic position.
Read Plant Growth Promoting Actinobacteria A New Avenue for Enhancing the Productivity and Soil Fertility of Grain Legumes by with Rakuten Kobo. Global yields of legumes have been relatively stagnant for the last five decades, despite the adoption of conventional a...
Sigma-Aldrich offers abstracts and full-text articles by [Feng Xie, Shengwang Dai, Jinzhao Shen, Biao Ren, Pei Huang, Qiushui Wang, Xueting Liu, Buchang Zhang, Huanqin Dai, Lixin Zhang].
Lineage: cellular organisms; Bacteria; Terrabacteria group; Actinobacteria; Actinobacteria; Bifidobacteriales; Bifidobacteriaceae; ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Actinomycetes are interesting as a main producer of secondary metabolites and industrial antibiotics from marine environments. A total of 44 strains of actinomycetes were isolated from Caspian Sea sediments at a depth of 5-10 m. Preliminary screening was done using cross-streak method against 2 gram-positive and 4 gram-negative pathogen bacteria. The most potent strains MN2, ...
RN [1] RM PMID:20675471 RT Unexpected abundance of coenzyme F(420)-dependent enzymes in Mycobacterium tuberculosis and other actinobacteria. RA Selengut JD, Haft DH RL J Bacteriol. 2010 Nov;192(21):5788-98. RN [2] RM PMID:16930487 RT Exopolysaccharide-associated protein sorting in environmental organisms: the PEP-CTERM/EpsH system. Application of a novel phylogenetic profiling heuristic. RA Haft DH, Paulsen IT, Ward N, Selengut JD RL BMC Biol. 2006 Aug 24;4:29 ...
Actinomycetes are gram-positive, free-living, saprophytic bacteria widely distributed in soil, water and colonizing plants showing marked chemical and morphological diversity. They are potential source of many bioactive compounds, which have diverse clinical effects and important applications in human medicine. In the present work, we have studied some of the physiological and biochemical characteristics of 36 actinomycete strains isolated from the shola soils of tropical montane forest; a relatively unexplored biodiversity hotspot. Ability of actinomycetes isolates to ferment and produce acids from various carbohydrate sources such as innositol, mannose, sorbitol, galactose, mannitol, xylose, rhamnose, arabinose, lactose and fructose were studied. Almost all the carbon compounds were utilized by one or other actinomycete isolates. The most preferred carbon sources were found to be xylose (94.44%) followed by fructose and mannose (91.66%). Only 41.76% of the isolates were able to ferment ...
Abstract: Actinomycetes are one of the most important groups that produce useful secondary metabolites. They play a great role in pharmaceutical and industrial uses. The search for antibiotic producing soil actinomycetes to inhibit the growth of pathogenic microorganisms has become widespread due to the need for newer antibiotics. The present work was aimed to isolate soil actinomycetes from pinus tree rhizosphere from Doddabetta, Western Ghats, Tamil Nadu, India. Thirty one actinomycetes were isolated based on heterogeneity and stability in subculturing; they were screened against 5 Gram positive and 7 Gram negative bacteria in an in vitro antagonism assay. In the preliminary screening, out of 31 isolates, 12.09% showed good antagonistic activity; 25.08% showed moderate activity; 19.35% showed weak activity and 41.93% showed no activity against the tested bacteria. Among the isolates tested, DPR20 showed good antibacterial activity against both Gram positive and Gram negative bacteria. The ...
This chapter discusses some of the stressors likely to target the cell envelope of Mycobacterium tuberculosis during infection, and the corresponding regulatory elements expressed by the bacterium to counteract this stress. Phylogenetically, M. tuberculosis is a member of the phylum Actinobacteria, which also includes several notable human pathogens, including species of the genera Streptomyces, Corynebacterium, Nocardia, and Rhodococcus. M. tuberculosis is a facultative intracellular pathogen, and its host range is restricted to humans. The bacterium is not normally found free within the environment, so its continued survival within the human population requires that it be transmitted directly from an infected individual with active disease to one that is susceptible to infection. Posttranslational phosphorylation of proteins was traditionally thought to be limited to eukaryotic cells. However, the discovery of two-component signal transduction systems (TCSSs) in bacteria shifted this paradigm to
The composting process is a complex interaction between the waste and the microorganisms within the waste. The microorganisms that carry out this process fall into three groups: bacteria, fungi, and actinomycetes. Actinomycetes are a form of fungi-like bacteria that break down organic matter. The first stage of the biological activity is the consumption of easily available sugars by […]. ...
The composting process is a complex interaction between the waste and the microorganisms within the waste. The microorganisms that carry out this process fall into three groups: bacteria, fungi, and actinomycetes. Actinomycetes are a form of fungi-like bacteria that break down organic matter. The first stage of the biological activity is the consumption of easily available sugars by […]. ...
A new hierarchic classification structure for the taxa between the taxonomic levels of genus and class is Proposed for the actinomycete line of descent as defined by analysis of small subunit (16S) rRNA and genes coding for this molecule (rDNA). While the traditional circumscription of a genus of the actinomycete subphylum is by and large in accord with the 16S rRNA/rDNA-based phylogenetic clustering of these organisms. most of the higher taxa proposed in the past do not take into account the phylogenetic clustering of genera. The rich chemical, morphological and physiological diversity of phylogenetically closely related genera makes the description of families and higher taxa so broad that they become meaningless for the description of the enclosed taxa. Here we present a classification system in which phylogenetically neighboring taxa at the genus level are clustered into families, suborders, orders, subclasses, and a class irrespective of those phenotypec characteristics on which the delineation of
Lineage: cellular organisms; Bacteria; Terrabacteria group; Actinobacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae; Amycolatopsis; Amycolatopsis ...
Methodology/Principal Findings: Here, we report molecular monitoring of the stone-autochthonous microbiota before and at 5, 12 and 30 months after the bio-consolidation treatment (medium/long-term monitoring), employing the well-known molecular strategy of DGGE analyses. Before the bio-consolidation treatment, the bacterial diversity showed the exclusive dominance of Actinobacteria (100%), which decreased in the community (44.2%) after 5 months, and Gamma-proteobacteria (30.24%) and Chloroflexi (25.56%) appeared. After 12 months, Gamma-proteobacteria vanished from the community and Cyanobacteria (22.1%) appeared and remained dominant after thirty months, when the microbiota consisted of Actinobacteria (42.2%) and Cyanobacteria (57.8%) only. Fungal diversity showed that the Ascomycota phylum was dominant before treatment (100%), while, after five months, Basidiomycota (6.38%) appeared on the stone, and vanished again after twelve months. Thirty months after the treatment, the fungal population ...
My main academic interests are in microbial systematics and biotechnology. One of my current research interests is to promote advances in, and enhance the general understanding of the extent of actinobacterial diversity in natural ecosystems and manmade habitats. To this end, innovative strategies are being developed for the selective isolation, dereplication and characterisation of actinomycetes using a range of genotypic and phenotypic procedures. One route that is being adopted for the discovery of novel actinomycetes is to determine the extent of actinobacterial diversity in neglected habitats, such as desert soils and deep sea muds, using both culture-based and culture independent approaches.. Background. My undergraduate and postgraduate studies were at the University of Liverpool where I gained a Ph.D. in 1966 for a research project that introduced me to the wonderful world of microbial diversity. My interests in microbial ecology and microbial systematics were further developed first as ...
Atopobium vaginae is a species of bacteria in the genus of Actinobacteria, in the family Coriobacteriaceae. It is a facultative anaerobic, Gram-positive rod-shaped or elliptical coccobacilli found as single elements or in pairs or short chains. It is typically isolated from 80% of women with bacterial vaginosis and it is implicated in treatment failures. Jovita, M. R.; Collins, M. D.; Sjoden, B.; Falsen, E. (1999). "Characterization of a novel Atopobium isolate from the human vagina: description of Atopobium vaginae sp. nov". International Journal of Systematic Bacteriology. 49 (4): 1573-1576. doi:10.1099/00207713-49-4-1573. ISSN 0020-7713. PMID 10555338. Mastromarino, Paola; Vitali, Beatrice; Mosca, Luciana (2013). "Bacterial vaginosis: a review on clinical trials with probiotics" (PDF). New Microbiologica. 36: 229-238. PMID 23912864. Polatti, Franco (2012). "Bacterial Vaginosis, Atopobium vaginae and Nifuratel". Current Clinical Pharmacology. 7 (1): 36-40. doi:10.2174/157488412799218824. ISSN ...
A taxonomic study was carried out to clarify the taxonomy of representatives of a group of marine actinomycetes previously designated MAR 1 and considered to belong to the family Micromonosporaceae. The organisms had phenotypic properties consistent with their assignment to this taxon. The strains formed a distinct taxon in the 16S rRNA Micromonosporaceae gene tree and shared a range of phenotypic properties that distinguished them from members of all of the genera with validly published names classified in this family. The name proposed for this novel taxon is Salinispora gen. nov. The genus contains two species recognized using a range of genotypic and phenotypic criteria, including comparative 16S-23S rRNA gene spacer region and DNA-DNA relatedness data. The names proposed for these taxa are Salinispora arenicola sp. nov., the type species, and Salinispora tropica sp. nov.; the type strains of these novel species have been deposited in service culture collections as strain CNH-643T (=ATCC BAA-917T
Looking for online definition of Actinobacteria in the Medical Dictionary? Actinobacteria explanation free. What is Actinobacteria? Meaning of Actinobacteria medical term. What does Actinobacteria mean?
Bioprospecting natural products in marine bacteria from fjord environments are attractive due to their unique geographical features. Although, Actinobacteria are well known for producing a myriad of bioactive compounds, investigations regarding fjord derived marine Actinobacteria are scarce. In this study, the diversity and biotechnological potential of Actinobacteria isolated from marine sediments within the Comau fjord, in Northern Chilean Patagonia, were assessed by culture-based approaches. The 16S rRNA gene sequences revealed that members phylogenetically related to the Micrococcaceae, Derrnabacteraceae. Brevibacteriaceae, Corynebacteriaceae. Microbacteriaceae, Dietziaceae, Nocardiaceae, and Streptomycetaceae families were present at the Comau fjord. A high diversity of cultivable Actinobacteria (10 genera) was retrieved by using only five different isolation media. Four isolates belonging to Arthrobacter, Brevibacterium, Corynebacterium and Kocuria genera showed 16S rRNA gene identity ...
International Journal of Evolutionary Biology is a peer-reviewed, Open Access journal that publishes original research articles as well as review articles in all areas of evolutionary biology.
Colin A. B. Davidson ,cabd2 at hermes.cam.ac.uk, wrote in message news:,9n500j$4hn$1 at pegasus.csx.cam.ac.uk,... , Daniel B. Wheeler ,dwheeler at ipns.com, wrote in message , news:6dafee1b.0109010714.23c083f0 at posting.google.com... , (CUT) , , BTW, the above total may sound overestimated by some. But when such , , things as rusts, smuts, ectomycorrhizae, endomycorrhizae, soil, and , , compost actinomycetes are added, , , Whoah there! , , Sorry to seem a pedant, but the actinomycetes are bacteria, not fungi :-) Ill take your word for it Colin. I have not studied the actinomycetes yet. But they sure sound similar to basidiomycetes and ascomycetes. Then, of course, theres the Termite mushrooms, Termitomyces... Sounds like the same to me. Of course, theres a lot of fungi I dont recognize yet. Thats what happens when you dont get a degree in mycology, I guess. , , ,it doesnt seem an overestimate (at , , least to me) at all. Then you have the newly discovered endophytic , , fungi, found ...
Similarly to their terrestrial relatives, marine microbes are a rich source of bioactive metabolites (antibiotics, antitumor drugs) and enzymes with different applications. For instance, cultivation of a marine actinomycete known as Salinispora tropica yielded a number of novel metabolites, not found before. One of these compounds, salinosporamide A, has antitumor properties and is currently being tested in humans for the treatment of cancer. Sequencing the genome of Salinispora tropica unveiled a number of genes coding for the synthesis of 17 potential metabolites; most of these compounds had not been detected in previous culturing of the microbe. Then, the researchers used the genetic information to guide a new chemical analysis of Salinispora cultures. The analysis uncovered an additional, novel compound (salinilactam), which had a structure corresponding to that deduced from the DNA sequence ...
Reference: EUZÉBY (J.P.) and TINDALL (B.J.): Nomenclatural type of orders: corrections necessary according to Rules 15 and 21a of the Bacteriological Code (1990 Revision) and designation of appropriate nomenclatural types of classes and subclasses. Request for an Opinion. Int. J. Syst. Evol. Microbiol. 2001, 51, 725-727 ...
In the era where large whole genome bacterial data sets are generated routinely, rapid and accurate molecular systematics is becoming increasingly important. However, 16S ribosomal RNA sequencing does not always offer sufficient resolution to discriminate between closely related genera. The SsgA-like proteins (SALPs) are developmental regulatory proteins in sporulating actinomycete, whereby SsgB actively recruits FtsZ during sporulation-specific cell division. Here we present a novel method to classify actinomycetes, based on the extraordinary way the SsgA and SsgB proteins are conserved. The almost complete conservation of the SsgB amino acid sequence between members of the same genus, and its high divergence even between closely related genera, provides high quality data for the classification of morphologically complex actinomycetes. Our analysis validates Kitasatospora as a sister genus to Streptomyces in the family Streptomycetaceae and suggests that Micromonospora, Salinispora and ...
Construction of a D-valine sensor using D-amino acid oxidase of Rubrobacter xylanophilus, Journal of Technology and Education, 2016/12/01, Katsumi TAKAYAMA, Chisato SAKAMOTO, Shouji TAKAHASHI, Katsumasa ABE, Ayano HIROBE, and Takeji KOSHIGIRI. ...
Researchers found that there was no significant difference between groups for body weight gain, overall caloric intake, body fat, lean mass, or overall adiposity index. Rats that consumed sugar water consumed less of the solid food. As a result of this well-established compensatory behavior in Sprague-Dawley rats, all three sugar groups consumed a significantly lower percentage of energy from fat and protein compared to the control.. The 16s rRNA sequencing of fecal samples taken at post-natal day 80 revealed a distinct clustering pattern when comparing the sugar to non-sugar fed rats. Interestingly, when comparing the 3 different fructose-to-glucose ratio groups, there was no distinct clustering pattern observed. Researchers detail a number of shifts in the microbiome at the phylum, class, order, family, and genus level. For example, at the phylum level, Proteobacteria and Actinobacteria were elevated in the sugar consuming groups. At the class level, Actinobacteria, Bacilli, Alpha-, Beta- and ...
Proteome IDi ,p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the ,a href="http://www.uniprot.org/manual/proteomes_manual">proteome,/a>. It consists of the characters UP followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.,p>,a href=/help/proteome_id target=_top>More...,/a>,/p> ...
Proteome IDi ,p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the ,a href="http://www.uniprot.org/manual/proteomes_manual">proteome,/a>. It consists of the characters UP followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.,p>,a href=/help/proteome_id target=_top>More...,/a>,/p> ...
The gut microbiome uses a number of diverse mechanisms to alter the disposition, efficacy and toxicity of drugs and xenobiotics as follows (Carmody and Turnbaugh, 2014; Klaassen and Cui, 2015): 1) The gut microbiota may express enzymes that either metabolically activate or inactivate drugs. For example, sulfalazine used to treat gut inflammation is converted to its pharmacologically active form, 5-amino 5-salicylic acid by microbial enzymes. In contrast, digoxin is inactivated by a "cardiac glycoside" expressed by Eggerthella lenta. 2) The drug may be sequestered by direct binding to the bacterial organism. An example here is the sequestration of L-DOPA by Helicobacter pylori. 3) The drug may be metabolically reactivated by microbially expressed enzymes. A good example of this mechanism is provided by the chemotherapeutic drug irinotecan (also called CPT-11) (Wallace et al., 2010). In the liver, irinotecan is metabolically inactivated via glucuronidation. Within the intestines, however, it is ...
A division of the Bacteria (Eubacteria) that has three classes, the anaerobic Clostridia, the aerobic Bacilli, and the Mollicutes (mycoplasmas). They differ from Actinobacteria in having low G+C levels in their DNA. Most, but not all, are Gram-positive. ...
Exploiting the genomes of the Actinobacteria: plant growth promoters and producers of natural products and energy relevant enzymes united in a taxonomically unresolved ...
ID CONWI_1_PE3285 STANDARD; PRT; 498 AA. AC CONWI_1_PE3285; D3FF04; DT 00-JAN-0000 (Rel. 1, Created) DT 00-JAN-0000 (Rel. 2, Last sequence update) DT 00-JAN-0000 (Rel. 3, Last annotation update) DE SubName: Full=Drug resistance transporter, EmrB/QacA subfamily; DE (CONWI_1.PE3285). GN OrderedLocusNames=Cwoe_3303; OS CONEXIBACTER WOESEI DSM 14684. OC Bacteria; Actinobacteria; Rubrobacteridae; Solirubrobacterales; OC Conexibacteraceae; Conexibacter. OX NCBI_TaxID=469383; RN [0] RP -.; RG -.; RL -.; CC -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CONWI_1.PE3285. CC Conexibacter woesei DSM 14684, complete genome. CC sequence. CC -!- ANNOTATIONS ORIGIN:D3FF04_CONWI CC -!- GENE_FAMILY: HOG000239124 [ FAMILY / ALN / TREE ] DR UniProtKB/Swiss-Prot; D3FF04; -. DR EMBL; CP001854; ADB51721.1; -; Genomic_DNA. DR RefSeq; YP_003395096.1; NC_013739.1. DR GeneID; 8733752; -. DR GenomeReviews; CP001854_GR; Cwoe_3303. DR KEGG; cwo:Cwoe_3303; -. DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. ...
Members of this protein family are Pup, a small protein whose ligation to target proteins steers them toward degradation. This protein family occurs in a number of bacteria, especially Actinobacteria such as Mycobacterium tuberculosis, that possess an archeal-type proteasome. All members of this protein family known during model construction end with the C-terminal motif [FY][VI]QKGG[QE]. Ligation is thought to occur between the C-terminal COOH of Pup and an epsilon-amino group of a Lys on the target protein. The N-terminal half of this protein is poorly conserved and not represented in the seed alignment ...
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Occurrence of pppApp-synthesizing activity in actinomycetes and isolation of purine nucleotide pyrophosphotransferase.: The occurrence of adenosine 5-triphosph
AbstractFull-Text PDF Full-Text HTML. Drug resistant and opportunistic organisms are a problem to medical health due to the fact that most of the drugs that were used are now not effective. Currently, there is a need to search for new drugs that can enhance the control of these organisms. Actinomycetes and their secondary metabolites can be used as such drugs. This study was designed to isolate actinomycetes producing novel anti-fungal compounds from waste... Read more. ...
In Mexiko haben sie erfolgreich vier jungen Damen Vaginae aus der Petrischale eingepflanzt. Die Mumus sind voll funktionsfähig. Science!
Ingrediente: 250 g faina, 150 g unt, 100 g zahar, 3 galbenusuri, un virf de cutit sare fina, coaja de lamiie, 50 g nuci macinate, 20 ml rom. Mod de preparare:
Results Median concentrations of A. vaginae and G. vaginalis were not significantly different among various age groups (A. vaginae p=0.98 and G. vaginalis p=0.18) or different trimesters (A. vaginae p=0.31 and G. vaginalis p=0.19), but differed significantly among the vaginal flora categories (A. vaginae p,0.001 and G. vaginalis p,0.001) and HIV status (A. vaginae p,0.001 and G. vaginalis p=0.004). The presence of A. vaginae (OR=5.8; 95% CI 1.34 to 25.21 and p value=0.02) but not that of G. vaginalis (OR=1.90; 95% CI 0.81 to 4.43 and p value=0.14) was associated with HIV infection. An A. vaginae DNA concentration of ≥107 copies/mL together with a positive G. vaginalis result (≥100 copies/mL) best discriminated between BV-positive (39/220) and non-BV categories (181/220) with a sensitivity of 85% (95% CI 0.70 to 0.94) and a specificity of 82% (95% CI 0.76 to 0.88). ...
Whipples disease is a rare systemic infectious disorder caused by Tropheryma whipplei. We report a 68-year-old male with Whipples disease of the central nervous system following long-term antibiotic therapy and many years after the initial clinical onset. The combination of trimethoprim and sulphamethoxazole does not prevent or cure involvement of the central nervous system in all patients with Whipples disease. If relapse of the central nervous system occurs treatment with meropenem might be a useful alternative.
Many times after a rain, there is a distinctive odor in the air - a sort of musky smell. This pleasant fragrance is most common in rains that follow a dry spell. If you are a gardener, you may find this smell similar to the smell you sense when you turn over your soil. Good organic soils contain bacteria. One bacterium that is abundant in damp warm soils is actinomycete.. Actinomycetes are a key ingredient in the decomposition of organic materials in the soil. These bacteria thrive when the soil is moist. When the soil dries out, the actinomycetes produce tiny spores. These spores are part of their reproduction cycle. Rain kicks up these spores when the raindrops hit the ground and make them airborne. Air movements then disperse the spores and carry some of the spores to our nose, where we detect a pleasant aroma. Actinomycetes are very common, which is why you experience the pleasing after-the-rain smell in many locations.. Winds can transport odors from areas upwind of you. We also can ...
Global Whipples Disease Market was around USD 206.2 million in 2016 and is expected to reach USD 255.3 million by 2023 at a projected CAGR of 3.1%,Whipples disease market by diagnosis,by treatment,by end use | Whipples Disease Industry
Microbes are extensively associated with insects, playing key roles in insect defense, nutrition and reproduction. Most of the associations reported involve Proteobacteria. Despite the fact that Actinobacteria associated with insects were shown to produce antibiotic barriers against pathogens to the hosts or to their food and nutrients, there are few studies focusing on their association with insects. Thus, we surveyed the Actinobacteria diversity on a specific region of the midgut of seven species of stinkbugs (Hemiptera: Pentatomidae) known to carry a diversity of symbiotically-associated Proteobacteria. A total of 34 phylotypes were placed in 11 different Actinobacteria families. Dichelops melacanthus held the highest diversity with six actinobacteria families represented by nine phylotypes. Thyanta perditor (n = 7), Edessa meditabunda (n = 5), Loxa deducta (n = 4) and Pellaea stictica (n = 3) were all associated with three families. Piezodorus guildini (n = 3) and Nezara viridula (n = 3) had the
ID BX251410; SV 1; linear; genomic DNA; STD; PRO; 324050 BP. XX AC BX251410; XX DT 17-FEB-2003 (Rel. 74, Created) DT 06-FEB-2015 (Rel. 123, Last updated, Version 4) XX DE Tropheryma whipplei TW08/27, complete genome; segment 1/3 XX KW complete genome. XX OS Tropheryma whipplei TW08/27 OC Bacteria; Actinobacteria; Micrococcales; Tropheryma. XX RN [1] RP 1-324050 RX DOI; 10.1016/S0140-6736(03)12597-4. RX PUBMED; 12606174. RA Bentley S.D., Maiwald M., Murphy L.D., Pallen M.J., Yeats C.A., Dover L., RA Norbertczak H.T., Besra G.S., Quail M.A., Harris D.E., von Herbay A., RA Goble A., Rutter S., Squares R., Squares S., Barrell B.G., Parkhill J., RA Relman D.A.; RT "Sequencing and analysis of the genome of the Whipples disease bacterium RT Tropheryma whipplei"; RL Lancet 361(9358):637-644(2003). XX RN [2] RP 1-324050 RA Bentley S.D.; RT ; RL Submitted (10-FEB-2003) to the INSDC. RL Submitted on behalf of the Pathogen Sequencing Unit, Sanger Institute, RL Wellcome Trust Genome Campus, Hinxton, ...
Whipple disease is a rare infectious multisystem disorder caused by the actinobacteria Tropheryma whipplei. Epidemiology The incidence of Whipple disease is not truly known, one Swiss study estimated it at approximately 1 per 1.5 million per ye...
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Laiz and her team studied three indoor sites showing overt biodeterioration: the Servilia and Postumio tombs in the Roman Necropolis of Carmona in Spain and the Vilar de Frades church in Portugal. Their microbiological and molecular analyses identified five new Rubrobacter strains. The strains are partly involved in the process of efflorescence formation, where salt residues form on buildings, due to the loss of water after exposure to air for a prolonged period of time. Efflorescences lead to damage in the porous structure of the rocks and the gradual deterioration of these buildings.. Two of the newly isolated strains were then grown onto rocks to replicate the biodeterioration process in the laboratory. The Rubrobacter cells penetrated the mineral matrix and crystals formed in contact with the bacterial film. When the film separated from the rock surface after exposure to heat, it removed mineral grains, producing a mechanical deterioration. These three processes are characteristic of ...
Whipples disease is a multisystemic disorder in which almost all organ systems can be invaded by rod-shaped bacteria. Without extended antimicrobial therapy, its course is lethal. Empirically,...
The sponge-associated actinomycetes were isolated from the marine sponge Dendrilla nigra, collected from the southwest coast of India. Eleven actinomycetes
Whipples disease, also known as intestinal lipodystrophy, is an extremely rare bacterial infection that typically affects the small intestine.
TY - JOUR. T1 - Structure assignment of lucentamycin e and revision of the olefin geometries of the marine-derived lucentamycins. AU - Cha, Jin Wook. AU - Park, Jin Soo. AU - Sim, Taebo. AU - Nam, Sang Jip. AU - Kwon, Hak Cheol. AU - Del Valle, Juan R.. AU - Fenical, William. PY - 2012/9/28. Y1 - 2012/9/28. N2 - A new lucentamycin analogue, lucentamycin E (5), was isolated from the culture broth of the marine-derived actinomycete Nocardiopsis lucentensis, strain CNR-712. The absolute stereostructure of 5 was assigned by comprehensive analyses of NMR data and by application of the advanced Marfeys method. The planar structure of 5 was analogous to lucentamycins A-D, whereas the olefin geometry of the 3-methyl-4-ethylideneproline moiety was found to be E, opposite of that previously reported. Consequently, a reinvestigation of the olefin geometries of the 3-methyl-4-ethylideneproline residues of lucentamycins A-D showed that the olefin geometries of the substituted proline functionalities must be ...
Function: Get / set the tab-delimited file that defines the OTU taxonomic assignemts. The first four columns (out of 12) should be: OTU ID, taxonomic string, E-value, taxonomic ID. For example: 345 k__Bacteria; p__Actinobacteria; c__Actinobacteria; o__Actinomycetales; f__Propionibacteriaceae; g__Propionibacterium; s__acnes 5e-138 1042485 95.67 300 13 0 1 300 878 579 346 k__Bacteria; p__Firmicutes; c__Bacilli; o__; f__; g__; s__ 8e-134 1064834 99.59 245 1 0 1 245 909 665 347 k__Bacteria; p__Proteobacteria; c__Gammaproteobacteria; o__Pseudomonadales; f__Pseudomonadaceae; g__Pseudomonas; s__ 2e-103 959954 98.99 198 2 0 103 300 718 521 The taxonomic assignment files generated by QIIME (rep_set_tax_assignments.txt) follow this format. Usage : $summarizer-,taxassign_file(rep_set_tax_assignments.txt); Args : taxonomic assignment file name Returns : taxonomic assignment file ...
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N-dimethyl-4-nitrosoaniline oxidoreductase alcohol - N: a group III alcohol oxidoreductase from Rhodococcus sp, Amycolatopsis methanolica and Mycobacterium gastri; amino acid sequence given in first source; GenBank U21071
Wink JM, Kroppenstedt RM, Ganguli BN, et al. 2003. Three new antibiotic producing species of the genus Amycolatopsis, Amycolatopsis balhimycina sp. Nov., Amycolatopsis tolypomycina sp. Nov., Amycolatopsis vancoresmycina sp. Nov., and description of Amycolatopsis keratiniphila subsp. Keratiniphila subsp. Nov. and Amycolatopsis keratiniphila subsp. Nogabecina subsp. Nov. Syst Appl Microbiol 26:38. PUBMED Abstract ...
விப்பிள் நோய் (Whipples disease) என்பது துரோபெரைமா விப்ளெய் எனும் பாக்டீரியாவினால் ஏற்படும் உடற்தொகுதி நோயாகும். சோர்ச் ஒய்ட் விப்பிள் 1907 இல் இதனை முதன்முதலில் கண்டறிந்தபோது இது சிறுகுடலில் உணவு அகத்துறிஞ்சாமையை ஏற்படுத்தும் இரையகக் குடலியநோய் என்று கருதினர். எனினும், மூட்டுக்கள், மைய நரம்புத் தொகுதி, குருதிச் சுற்றோட்டத் தொகுதி, நுரையீரல் தொகுதி போன்ற வேறு ஒருங்கியங்களையும் ...
Streptomyces sp. belongs to Streptomyces, the largest genus of Actinobacteria and the type genus of the family Streptomycetaceae.
Title: mama vaginae sex video. Duration: 0:00. Submited by: xnxx. Category: Amateur, Anal Sex, Asian Woman, Aunty, BBW, blog, College. Added on: June 3rd, 2016. ...
Biochemists at the University of Bayreuth and the University of Bonn have now discovered a way to regulate this process which is central to gene expression: Certain actinobacteria contain a protein that binds RNA molecules under blue light and can thereby deactivate them. [47] A new piece of a difficult puzzle-the nature of memory-fell into place this week with a hint at how brain cells change structure when they learn something. [46] Researchers at the University of Alberta have found an important protein in the cells of a deadly infectious parasite, opening the door to less harmful treatment for millions of people suffering from diseases like sleeping sickness in Africa and Chagas disease in South America. [45] ...
The first description of Whipple disease was reported in 1907 by George Whipple. The causative agent of this disease is T. whipplei, a Gram-positive Actinobacterium. In 1991, a PCR assay was developed providing an excellent tool for the diagnosis of the disease [3]. Infection occurs via the gastrointestinal route with intensive macrophage recruitment and activation. It predominantly occurs in males (8:1 male-to-female ratio). As in other inflammatory diseases, genetic susceptibility probably plays an important role. A defect in cellular immune response may predispose to infection and might explain the rarity of the disorder despite the ubiquitous presence of T. whipplei, but the immunological defect is, in some way, probably specific to this pathogen since other infections do not occur more frequently. Humoral response does not appear to be affected, with normal levels of IgG and IgM. Moreover, the impaired immunity is probably also increased by the presence of T. whipplei. Macrophages from ...
Biohazard level, growth media and temperature, gram stain, industrial applications and more information for Amycolatopsis sulphurea.
Board Member Uli has been a board member at Axon Vibe since 2008. His investments focus on early stage and growth stage companies mainly in Europe and China. His portfolio includes activities in the medical devices, IT/Internet, green technologies, industrials and financial services sector. Outside of the corporate world, Uli is a passionate art collector with the largest collection of Chinese contemporary art.
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TY - JOUR. T1 - Sicca syndrome associated with Tropheryma whipplei intestinal infection. AU - Bosman, Cesare. AU - Boldrini, Renata. AU - Borsetti, Giuliana. AU - Morelli, Sergio. AU - Paglia, Maria Grazia. AU - Visca, Paolo. PY - 2002/8/1. Y1 - 2002/8/1. N2 - The case of a 61-year-old woman with Whipples disease-associated sicca complex is reported. Tropheryma whipplei infection was diagnosed by histological and ultrastructural examination of the jejunal mucosa and sequence analysis of the bacterial 16S ribosomal DNA. The role of vitamin A malabsorption in sicca complex secondary to Whipples disease is discussed.. AB - The case of a 61-year-old woman with Whipples disease-associated sicca complex is reported. Tropheryma whipplei infection was diagnosed by histological and ultrastructural examination of the jejunal mucosa and sequence analysis of the bacterial 16S ribosomal DNA. The role of vitamin A malabsorption in sicca complex secondary to Whipples disease is discussed.. UR - ...
Symbiobacterium toebii is a commensal symbiotic thermophile that absolutely requires its partner bacterium Geobacillus toebii for growth. Despite development of an independent cultivation method using cell-free extracts, the growth of Symbiobacterium remains unknown due to our poor understanding of the symbiotic relationship with its partner bacterium. Here, we investigated the interrelationship between these two bacteria for growth of S. toebii using different cell-free extracts of G. toebii. Symbiobacterium toebii growth-supporting factors were constitutively produced through almost all growth phases and under different oxygen tensions in G. toebii, indicating that the factor may be essential components for growth of G. toebii as well as S. toebii. The growing conditions of G. toebii under different oxygen tension dramatically affected to the initial growth of S. toebii and the retarded lag phase was completely shortened by reducing agent, L-cysteine indicating an evidence of commensal interaction of
Whipples disease is a chronic, systemic infection caused by Tropheryma whipplei. Gene amplification, isolation and DNA sequencing of T whipplei have extended our knowledge of this pathogen, which is now recognised as a ubiquitous commensal bacterium. The spectrum of signs associated with T whipplei has now been extended beyond the classic form, which affects middle-aged men, and begins with recurrent arthritis followed several years later by digestive problems associated with other diverse clinical signs. Children may present an acute primary infection, but only a small number of people with a genetic predisposition subsequently develop authentic Whipples disease. This bacterium may also cause localised chronic infections with no intestinal symptoms: endocarditis, central nervous system involvement, arthritis, uveitis and spondylodiscitis. An impaired TH1 immune response is seen. T whipplei replication in vitro is dependent on interleukin 16 and is accompanied by the apoptosis of host cells, ...
Whipple disease is a systemic disease most likely caused by a gram-positive bacterium, Tropheryma whippelii. Although the first descriptions of the disorder described a malabsorption syndrome with small intestine involvement, the disease also affects the joints, central nervous system, and cardiovascular system.
TY - JOUR. T1 - Primary Whipple disease of the Central Nervous System presenting with rhombencephalitis. AU - Balducci, Claudia. AU - Foresti, Sergio. AU - Ciervo, Alessandra. AU - Mancini, Fabiola. AU - Nastasi, Giulia. AU - Marzorati, Laura. AU - Gori, Andrea. AU - Ferrarese, Carlo. AU - Appollonio, Ildebrando. AU - Peri, Anna Maria. PY - 2019/11. Y1 - 2019/11. N2 - Primary Whipple disease of the Central Nervous System is a rare entity whose outcome might be fatal if not promptly diagnosed and treated. Few cases are reported in the literature with heterogeneous clinical and radiological presentations which often make the diagnosis extremely challenging. We report a case of primary Whipple disease of the Central Nervous System presenting with rhombencephalitis in a female patient in immunosuppressive treatment for rheumatoid arthritis. We describe the management of our patient and discuss the features of this rare clinical entity.. AB - Primary Whipple disease of the Central Nervous System is a ...
Background:Tropheryma whipplei causes acute diseases, such as gastroenteritis, bacteremia, and pneumonia (1), as well as chronic Whipple disease (2). It can be cultivated from stool samples, which are a potential source of infection (3). Detection of T. whipplei DNA in saliva also suggests an oral-oral method of transmission. However, cultivation of T. whipplei from saliva has been impossible because of heavy contamination by other bacteria ...
Market Research Future adds new report of "Whipples Disease Market Research Report - Global Forecast till 2023" it contains Company information, geographical data and Table of Content. Competitive Analysis:. Some of the key players in this market: AbbVie Inc. (US), Allergan (Republic of Ireland), Bayer AG (Germany), Bristol-Myers Squibb Company (US), F. Hoffmann-La Roche Ltd. (Switzerland), Henry Schein, Inc. (US), Pfizer Inc. (US). Market Segments:. The global Whipples disease market is segmented on the basis of diagnosis, which includes physical exam, biopsy, blood tests, polymerase chain reaction, endoscopy, and others. Biopsy plays important role in diagnosis of this disorder, these tests include needle biopsy, CT-guided biopsy, ultrasound-guided biopsy, aspiration biopsy (fine-needle aspiration), skin biopsy, surgical biopsy, and others. Blood tests sub-segmented into Complete blood count (CBC), Red Blood Cell Count (RBC), serum albumin test, total protein test, and others. On the basis ...
Market Research Future adds new report of "Whipples Disease Market Research Report - Global Forecast till 2023" it contains Company information, geographical data and Table of Content. Competitive Analysis:. Some of the key players in this market: AbbVie Inc. (US), Allergan (Republic of Ireland), Bayer AG (Germany), Bristol-Myers Squibb Company (US), F. Hoffmann-La Roche Ltd. (Switzerland), Henry Schein, Inc. (US), Pfizer Inc. (US). Market Segments:. The global Whipples disease market is segmented on the basis of diagnosis, which includes physical exam, biopsy, blood tests, polymerase chain reaction, endoscopy, and others. Biopsy plays important role in diagnosis of this disorder, these tests include needle biopsy, CT-guided biopsy, ultrasound-guided biopsy, aspiration biopsy (fine-needle aspiration), skin biopsy, surgical biopsy, and others. Blood tests sub-segmented into Complete blood count (CBC), Red Blood Cell Count (RBC), serum albumin test, total protein test, and others. On the basis ...
In our study, 105 of the ant colonies used were from four genera of fungus-growing ants: Apterostigma, Mycetarotes, Trachymyrmex and Acromyrmex. In each of these four genera, workers both carry an abundance of visible white bloom of Actinobacteria on their cuticle (figure 1 and electronic supplementary material, figure S1a) and are large enough to facilitate targeted isolations of localized growth of Actinobacteria. In all of these ant colonies, multiple colony-forming units (CFUs) of morphologically similar Actinobacteria (see electronic supplementary material, figure S1b-d) were obtained from ant cuticles, and sequencing confirmed that these isolates were Pseudonocardia. We also isolated Pseudonocardia from the other five genera of fungus-growing ants examined: Myrmicocrypta, Mycocepurus, Mycetosoritis, Cyphomyrmex and Atta. One, three and four colonies of Mycetosoritis, Mycocepurus, Myrmicocrypta ants were sampled, respectively, and each ant colony yielded CFUs of morphologically similar ...
Entre as Actinobacteria están algunhas das bacterias máis comúns no solo, auga doce, e vida mariña. Xogan un importante papel na descomposición de materiais orgánicos, como a celulosa e quitina, e na reciclaxe da materia orgánica e ciclo do carbono. Repoñen os nutrientes que perde o solo e son importantes na formación do humus. Outras Actinobacteria viven en plantas e animais, e algunhas son patóxenas, como Mycobacterium, Corynebacterium, Nocardia, Rhodococcus e algúns Streptomyces. As Actinobacteria son coñecidas como produtores de metabolitos secundarios de gran interese farmacolóxico e comercial, como aminoácidos, vitaminas, saborizantes, derivados lácticos ou antibióticos. En 1940 Selman Waksman descubriu que as bacterias do solo que estaba estudando producían actinomicina, un descubrimento polo cal recibiu o premio Nobel. Desde entón, descubríronse centos de antibióticos naturais producidos por estes microorganismos terrestres, especialmente os do xénero Streptomyces. ...
Metagenomic studies confirm that obesity is associated with a composition of gut microbiota. There are some controversies, however, about the composition of gut microbial communities in obese individuals in different populations. To examine the association between body mass index and microbiota composition in Ukrainian population, fecal concentrations of Bacteroidetes, Firmicutes, Actinobacteria and Firmicutes/Bacteroidetes (F/B) ratio were analyzed in 61 adult individuals. The relative abundance of Actinobacteria was small (5-7%) and comparable in different BMI categories. The content of Firmicutes was gradually increased while the content of Bacteroidetes was decreased with increasing body mass index (BMI). The F/B ratio also raised with increasing BMI. In an unadjusted logistic regression model, F/B ratio was significantly associated with BMI (OR = 1.23, 95% CI 1,09-1,38). This association continued to be significant after adjusting for confounders such as age, sex, tobacco smoking and physical
Accepted name: alcohol dehydrogenase (nicotinoprotein). Reaction: ethanol + acceptor - acetaldehyde + reduced acceptor. Other name(s): nicotinoprotein alcohol dehydrogenase; np-ADH; NDMA-dependent alcohol dehydrogenase; ethanol:N,N-dimethyl-4-nitrosoaniline oxidoreductase. Systematic name: ethanol:acceptor oxidoreductase. Comments: Contains Zn2+. Nicotinoprotein alcohol dehydrogenases are unique medium-chain dehydrogenases/reductases (MDR) alcohol dehydrogenases that have a tightly bound NAD+/NADH cofactor that does not dissociate during the catalytic process. Instead, the cofactor is regenerated by a second substrate or electron carrier. While the in vivo electron acceptor is not known, N,N-dimethyl-4-nitrosoaniline (NDMA), which is reduced to 4-(hydroxylamino)-N,N-dimethylaniline, can serve this function in vitro. The enzyme from the Gram-positive bacterium Amycolatopsis methanolica can accept many primary alcohols as substrates, including benzylalcohol [1].. Links to other databases: BRENDA, ...
Termites play a major role in foraging and degradation of plant biomass as well as cultivating bioactive microorganisms for their defense. Current advances in "omics sciences are revealing insights into function-related presence of these symbionts, and their related biosynthetic activities and genes identified in gut symbiotic bacteria might offer a significant potential for biotechnology and biodiscovery. Actinomycetes have been the major producers of bioactive compounds with an extraordinary range of biological activities. These metabolites have been in use as anticancer agents, immune suppressants, and most notably, as antibiotics. Insect-associated actinomycetes have also been reported to produce a range of antibiotics such as dentigerumycin and mycangimycin. Advances in genomics targeting a single species of the unculturable microbial members are currently aiding an improved understanding of the symbiotic interrelationships among the gut microorganisms as well as revealing the taxonomical ...
Buy Actisite Online! Actisite is a broad-spectrum polyketide antibiotic produced by the Streptomyces genus of actinobacteria. It has a role as an antimicrobial agent, an antibacterial drug, an antiprotozoal drug, a protein synthesis inhibitor and an Escherichia coli metabolite.
Isolation of actinomycetes from maize rhizosphere from Kupang, East Nusa Tenggara Province, and evaluation of their antibacterial, antifungal, and extracellular enzyme activity
Proportion of patients with HLA-DQB1 06 among patients with a chronic infection with T. whipplei (defined by classic Whipple disease and / or endocarditis and/or encephalitis) versus asymptomatic ...
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