Actinobacillus suis Activity Persists | National Hog Farmer
A little over two years ago, we commented on a general rise in the frequency of Actinobacillus suis (A. suis) isolation from our swine tissue submission cases, and wondered if it was related to the increased porcine circovirus type 2 (PCV2) activity (National Hog Farmer North American Preview, June 6, 2008).
Isolation of Actinobacillus suis from a cats lung - DTU Orbit
Actinobacillus suis has been isolated from the lungs of a 9-month-old cat. The bacterium was characterized biochemically as well as genetically, and its sensitivity profile to different antimicrobial agents was established. The role of this isolate in the cats condition is discussed ...
KEGG PATHWAY: Nucleotide excision repair - Actinobacillus suis H91-0380
Nucleotide excision repair (NER) is a mechanism to recognize and repair bulky DNA damage caused by compounds, environmental carcinogens, and exposure to UV-light. In humans hereditary defects in the NER pathway are linked to at least three diseases: xeroderma pigmentosum (XP), Cockayne syndrome (CS), and trichothiodystrophy (TTD). The repair of damaged DNA involves at least 30 polypeptides within two different sub-pathways of NER known as transcription-coupled repair (TCR-NER) and global genome repair (GGR-NER). TCR refers to the expedited repair of lesions located in the actively transcribed strand of genes by RNA polymerase II (RNAP II). In GGR-NER the first step of damage recognition involves XPC-hHR23B complex together with XPE complex (in prokaryotes, uvrAB complex). The following steps of GGR-NER and TCR-NER are similar ...
KEGG PATHWAY: Homologous recombination - Actinobacillus suis H91-0380
Homologous recombination (HR) is essential for the accurate repair of DNA double-strand breaks (DSBs), potentially lethal lesions. HR takes place in the late S-G2 phase of the cell cycle and involves the generation of a single-stranded region of DNA, followed by strand invasion, formation of a Holliday junction, DNA synthesis using the intact strand as a template, branch migration and resolution. It is investigated that RecA/Rad51 family proteins play a central role. The breast cancer susceptibility protein Brca2 and the RecQ helicase BLM (Bloom syndrome mutated) are tumor suppressors that maintain genome integrity, at least in part, through HR ...
SCIENTIFIC PAPERS & POSTERS - Scancell
Monoclonal Antibody Targeting Sialyl-di-Lewisa - Containing Internalizing and Noninternalizing Glycoproteins with Cancer Immunotherapy Development Potential. Silvana T. Tivadar, Richard S. McIntosh, Jia Xin Chua, Robert Moss, Tina Parsons, Abed M. Zaitoun, Srinivasan Madhusudan, Lindy G. Durrant and Mireille Vankemmelbeke. ABSTRACT: Tumor glycans constitute attractive targets for therapeutic antibodies. The sialylated glycocalyx plays a prominent role in cancer progression and immune evasion. Here, we describe the characterization of the mAb, FG129, which targets tumor-associated sialylated glycan, and demonstrate its potential for multimodal cancer therapy. FG129, obtained through BALB/c mouse immunizations with liposomes containing membrane glycan extracts from the colorectal cancer cell line LS180, is an mIgG1k that targets sialyl-di-Lewisa-containing glycoproteins. FG129, as well as its chimeric human IgG1 variant, CH129, binds with nanomolar functional affinity to a range of colorectal, ...
Porcine Lungs Come to Life at UTMB - IngMar Medical
The use of the porcine lung to demonstrate recruitment maneuvers stimulated us to consider the possibility of using the ASL 5000 to investigate ways to improve protocols for the handling of ex-vivo perfused lungs. We believe this would provide interesting research projects for students and faculty. Many of the current ex-vivo perfusion protocols involve using positive pressure and high concentrations of oxygen to maintain isolated perfused lungs. The longest time that perfused lungs have been kept viable ex-vivo is about 10 hours. Using the ASL 5000 to model breathing, we would like to explore the possibility of extending survival time of ex-vivo perfused lungs. We believe that lowering the FiO2 and avoiding positive pressure ventilation could improve viability. Further development of this model could lead to advances in therapeutics related to airway clearance, mechanical ventilation, and airway pharmacology.. In the video below, the porcine lungs are attached to an Avea ventilator in the CPAP ...
Streptococcus suis cps7 : an emerging virulent sequence type (ST29) shows a distinct, IgM-determined pattern of bacterial...
Streptococcus (S.) suis is an important porcine pathogen causing meningitis, arthritis and septicemia. As cps7 emerged recently in Germany in association with severe herd problems, the objective of this study was to characterize the geno- and phenotype of invasive cps7 strains. Twenty cps7 strains were isolated from diseased pigs from different farms with S. suis herd problems due to meningitis and other pathologies. Eighteen of the cps7 isolates belonged to sequence type (ST) 29. Most of these cps7 strains secreted a short MRP variant in agreement with a premature stop codon. Expression of Ide
Ssuis
, an IgM specific protease, was variable in four further investigated cps7 ST29 isolates. Bactericidal assays revealed very high survival factors of these four cps7 ST29 strains in the blood of weaning piglets. In growing piglets, the increase of specific IgM led to efficient killing of cps7 ST29 as shown by addition of the IgM protease Ide
Ssuis
A novel biosimulator based on |em|ex vivo|/em| porcine lungs for training in peripheral tissue sampling using endobronchial...
A novel biosimulator based on ex vivo porcine lungs for training in peripheral tissue sampling using endobronchial ultrasonography with a guide sheath
Suis togol - Pengedar Komponen Elektronik | Infinity-Electron.com
Senarai Produk Suis togol. Beli komponen elektronik Suis togol dari pengedar komponen elektronik terbesar dan terpantas di dunia - Infinity-Electron.com
Become an Affiliated Researcher | Ontario Swine Research Network
The goal of the Ontario Swine Research Network is to enhance and improve the timeliness and accuracy of UofG swine research results and activities to end-users. We also aim to highlight the ongoing collaborative work taking place with other institutions and research partners, in order to capture the provincial, national and international impact of the UofG swine research program. We hope this central website will provide a platform where producers, veterinarians, industry, students and other end-users can go for current and archived research results.. ...
Browse by Authors and Editors - Nottingham ePrints
Harrison, Freya and Muruli, Aneesha and Higgins, Steven and Diggle, Stephen P. (2014) Development of an ex vivo porcine lung model for studying growth, virulence, and signaling of Pseudomonas aeruginosa. Infection and Immunity, 82 (8). pp. 3312-3323. ISSN 1098-5522 ...
Dissertation
Streptococcus (S.) suis is one of the most important porcine pathogens with increasing attention as a zoonotic agent predominately in Asia. In pigs, S. suis frequently colonizes the mucosa of the upper respiratory tract without causing disease. However, S. suis can also cause invasive diseases such as septicemia, endocarditis, and meningitis. Little is known about the pathogenicity of S. suis. On the one hand, pathogenicity of S. suis is determined by the expression of virulence factors. On the other hand, S. suis needs to efficiently adapt to different host environments with varying nutrient compositions such as the mucosal tissue of the upper respiratory tract, the blood circulation system, and the cerebrospinal fluid (CSF). One main objective of this work was the characterization of the metabolic adaptation of S. suis to its host. Furthermore, this work provides evidence how pivotal metabolic processes are regulated and how metabolic adaptation influences virulence of S. suis. Following aims ...
poractant alfa - Curosurf Summary Report | CureHunter
poractant alfa: RN given refers to cpd with unknown MF; isolated from porcine lungs; contains approx 99% phospholipids and 1% hydrophobic low MW (
Immunoglobulin therapy - Wikipedia
The precise mechanism by which immunoglobulin therapy suppresses harmful inflammation is likely multifactorial. For example, it has been reported that immunoglobulin therapy can block Fas-mediated cell death.[23] Perhaps a more popular theory is that the immunosuppressive effects of immunoglobulin therapy are mediated through IgGs Fc glycosylation. By binding to receptors on antigen presenting cells, IVIG can increase the expression of the inhibitory Fc receptor, FcgRIIB, and shorten the half-life of auto-reactive antibodies.[24][25][26] The ability of immunoglobulin therapy to suppress pathogenic immune responses by this mechanism is dependent on the presence of a sialylated glycan at position CH2-84.4 of IgG.[24] Specifically, de-sialylated preparations of immunoglobulin lose their therapeutic activity and the anti-inflammatory effects of IVIG can be recapitulated by administration of recombinant sialylated IgG1 Fc.[24] There are several other proposed mechanisms of action and the actual ...
Actinobacillus hominis
Biohazard level, growth media and temperature, gram stain, industrial applications and more information for Actinobacillus hominis.
actinobacillus [laenfermeria WIKI]
Actinobacillus equulis: especie que se encuentra en la cavidad bucal y amígdalas del caballo y causa lesiones supurativas de los riñones y articulaciones de los cerdos y caballos y endocarditis en el cerdo ...
Quantifying the growth of Chlamydia suis in cell culture using high-content microscopy
article{8506862, abstract = {The porcine pathogen Chlamydia suis is widespread in pig farming. Isolation of Chlamydia suis in cell culture is crucial for the generation and characterization of new isolates. However, isolation of Chlamydia suis strains from field samples is fastidious. Therefore, we exploited high-content microscopy to quantify the growth of Chlamydia suis strains in different cell lines. We found that the cell line yielding optimal propagation of Chlamydia suis differed among isolates, and we identified cell lines outperforming those routinely used for chlamydial isolation. We conclude that adaptation of the propagation procedure to the origin of the putative field isolate is highly recommended to improve the recovery rate.}, author = {De Puysseleyr, Leentje and De Puysseleyr, Kristien and Vanrompay, Daisy and De Vos, Winnok}, issn = {1059-910X}, journal = {MICROSCOPY RESEARCH AND TECHNIQUE}, keyword = {Chlamydia,cell culture,high-content microscopy,isolation,swine,GNOTOBIOTIC ...
OPUS at UTS: Extracellular actin is a receptor for Mycoplasma hyopneumoniae - Open Publications of UTS Scholars
2018 Raymond, Madhkoor, Schleicher, Uphoff, Turnbull, Whitchurch, Rohde, Padula and Djordjevic. Mycoplasma hyopneumoniae, an agriculturally important porcine pathogen, disrupts the mucociliary escalator causing ciliostasis, loss of cilial function, and epithelial cell death within the porcine lung. Losses to swine production due to growth rate retardation and reduced feed conversion efficiency are severe, and antibiotics are used heavily to control mycoplasmal pneumonia. Notably, little is known about the repertoire of host receptors that M. hyopneumoniae targets to facilitate colonization. Here we show, for the first time, that actin exists extracellularly on porcine epithelial monolayers (PK-15) using surface biotinylation and 3D-Structured Illumination Microscopy (3D-SIM), and that M. hyopneumoniae binds to the extracellular β-actin exposed on the surface of these cells. Consistent with this hypothesis we show: (i) monoclonal antibodies that target β-actin significantly block the ability of ...
Citation tools | Infection and Immunity
Modun, Belinda, and Paul Williams. The Staphylococcal Transferrin-Binding Protein Is a Cell Wall Glyceraldehyde-3-Phosphate Dehydrogenase. Infection and Immunity 67.3 (1999): 1086-1092. Web. 29 Mar. 2020. ...
Highly Corrective Lifting Serum - Je Suis Collagène® Sérum De Liftant - Generation Joy
Je Suis Collagène® Highly Corrective Lifting Serum Excess skin cells are invisible to the naked eye. They make the skin appear dull and lifeless. Je Suis Collag
Actinobacillus capsulatus | Article about Actinobacillus capsulatus by The Free Dictionary
Looking for Actinobacillus capsulatus? Find out information about Actinobacillus capsulatus. A genus of gram-negative, immotile and nonspore-forming, oval to rod-shaped, often pleomorphic bacteria which occur as parasites or pathogens in mammals ,... Explanation of Actinobacillus capsulatus
Ici, je suis
Its a compilation of the many poems I wrote while I had a lot on my mind. Its not much, but its not bad either... The title is in French and it meaIm Not Angry, I Am Anger Im not Angry, I am Anger. Completely personified Finally realized, The World hating itself Killing itself Passively A......Read the poem free on Booksie.
spectro-aras.com • View topic - V2211 Cyg
Comme je nai pas trouvé de référence qui couvre la zone 500nm-620nm je me suis abstenu de nommer les raies car le spectre et assez touffu et il nest pas très facile de sy retrouver ...
O P I U M H U M : Shudder to Think - Get Your Goat (1992)
I cant help but associate this band with Beavis & Butt-Head, since my introduction to them was the boys commentary on Hit Liquor where they primarily talk about Don Henley and necrophilia. Thanks for putting this one up, havent heard it yet.. ReplyDelete ...
Actinobacillus pleuropneumoniae ApaA protein Summary Report | CureHunter
Actinobacillus pleuropneumoniae ApaA protein: an antigenic membrane protein from Actinobacillus pleuropnemoniae homology to ABC transporters; amino acid sequence in first source
Actinobacillus pleuropneumoniae (Shope) Pohl et al. ATCC ® 33590&t
Actinobacillus pleuropneumoniae ATCC ® 33590™ Designation: Femo TypeStrain=True Application: Characterization Respiratory research
Cerrone - Je Suis Music - Music Forecast
レーベル:CBS - CBS 6919フォーマット:Vinyl, 12, 45 RPM, Promo国:Netherlandsリリース済み:1978メディアの状態: Near Mint (NM or M-) スリーブの状態: Very Good Plus (VG+) 収録曲A Je Suis MusicB Rocket In The PocketHarveyもプレイするガラージクラッシクJe Suis Musicに、ヒップホップのサンプリングネタでお馴染みのRocket In The Pocketを収録した人気シングル。
PPT - Lets recap ! PowerPoint Presentation - ID:2220681
Lets recap !. Translate into English. Je suis parfois distrait. I am sometimes absent- minded . Je suis très généreux. I am very generous . Je suis assez gentil. I am quite kind . I am rather kind . Je ne suis pas très jaloux. I am not very jealous. Slideshow 2220681...