Early pregnancy termination: a comparison between vacuum aspiration and medical abortion using prostaglandin (16,16 dimethyl-trans-delta 2-PGE1 methyl ester) or
The main purpose of our study was to which determine factors, those measured by ultrasound and also demographic and clinical factors (age, number of previous pregnancies, abortions and deliveries) predict outcome of medical treatment for early pregnancy failure. Our hypothesis was that gestational sac volume predicts outcome of medical treatment for early pregnancy failure ...
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. ...
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Results: The success rate is greater in mifepristone with misoprostol group with 98% than misoprostol group with 90% Mean induction abortion interval from the insertion of the first misoprostol tablet is significantly shorter in the mifepristone pretreated group 12.93+4.19 hr as compared to 19.18+3.97 hr in the misoprostol alone group (p,0.001). The mean dose of the misoprostol required is significantly less in the mifepristone group as against misoprostol group (p=0.008). The side effects and complications observed in both the groups are mainly nausea vomiting, fever, abdominal cramps, bleeding, rigor, dizziness, retained products of consumption and these side effects are more in misoprostol group ...
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OBJECTIVE To compare the efficacy of 400 microg of misoprostol with that of 1 mg of gemeprost as cervical priming agents when administered vaginally 3 to 4 hours before first-trimester vacuum aspiration abortion. METHODS In a prospective controlled trial 90 nulliparous women who requested termination of pregnancy before 12 weeks gestation were randomized to receive vaginally either misoprostol or gemeprost for cervical priming. The force to dilate the cervix was measured by the use of a cervical tonometer connected to Hegar dilators from 3 to 10 mm. The main outcome measures were baseline cervical dilation; the peak force to dilate the cervix at 8, 9, and 10 mm; and the cumulative force to dilate the cervix to 10 mm. RESULTS Baseline cervical dilation did not differ significantly between the women who received misoprostol and those who were treated with gemeprost. Neither the peak force required to dilate the cervix at 8, 9, and 10 mm nor the cumulative force to dilate the cervix to 10 mm showed
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A Cervical pregnancy is an ectopic pregnancy that has implanted in the uterine endocervix. Such a pregnancy typically aborts within the first trimester, however, if it is implanted closer to the uterine cavity - a so-called cervico-isthmic pregnancy - it may continue longer. Placental removal in a cervical pregnancy may result in major hemorrhage. The incidence has been reported to be about 1:1,000 to 1: 16,000 pregnancies. Pregnancies involving the isthmus - the segment of the uterus between the cervix and the fundus - are more common than true cervical pregnancies. While in many situations the cause of the abnormal implantation remains unclear, there is evidence to link the development of cervical pregnancy to uterine instrumentation, specifically repeated D&Cs (dilatation and curettage). Cervical pregnancies are to be distinguished from pregnancies that start from an implantation in a scar of a previous cesarean section, so-called scar pregnancies. The diagnosis is made in asymptomatic ...
This present randomized controlled study conducted at Government Kasturba Gandhi Hospital for Women and Children, Chennai during the period 2004 -2006 evaluated the efficacy of the three regimens of vaginal misoprostol in the termination of first trimester of pregnancy. Total of 300 women who attended the family planning clinic requesting for first trimester termination of pregnancy were included in the study. The efficacy of three regimens of vaginal misoprostol was compared in terms of Induction - Abortion interval, complete abortion, incomplete abortion and incidence of side effects and the results were statistically analyzed. Observations in this study include, • Most of the patients were in the age group of 21 - 30 years (78%). • 82% of the women were parous, only 18% were nullipara. • Most of the women were belonged to class IV / V Socioeconomic status (85%). • 73% of the patients belonged to 10 - 12 weeks of gestation though they were selected at random basis. • In the study, IA ...
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Human Reproduction. Advance Access, May 5, 2005, pp 1-7.. 55. Hedley, Ellertson, Trussell ed, Accounting for time: Insights from a life-table analysis of the efficacy of medical abortion. American Journal of Obstetrics and Gyneacology (2004) 191, pp 1928-33. 56. Timothy Craig, Cathy Mende. Common allergic and allergic-like reactions to medications. Postgraduate Medicine, vol105/ no 3/ March 1999. 57. Prof P Potter, Allergy society of South Africa Retrieved August 12, 2005. 58. G William Palmer, Stephen Dreskin, Anaphylaxis. E-Medicine, October 2004. pp 3. Retrieved August 12, 2005. 59. Hamoda, Ashok, Flett, Templeton, A randomized controlled trial of Mifepristone in combination with misoprostol administered sublingually or vaginally for medical abortion up to 13 weeks of gestation. BJOG 2005 Aug; 112(8): 1102-8. 60. CBC trust. 61. Middleton T, Schaff EA, Fielding SL, Scahill M, Shannon C, Westheimer E, Wilkinson T, Winikoff B. Randomized trial of mifepristone and buccal or vaginal misoprostol ...
Use misoprostol as directed by your doctor. Check the label on the medicine for exact dosing instructions. An extra patient leaflet is available with misoprostol. Talk to your pharmacist if you have questions about this information. Take misoprostol by mouth with food unless your doctor tells you otherwise. The last dose of the day should be taken at bedtime. Taking misoprostol after meals and at bedtime may decrease the risk of diarrhea. Do not take an antacid that has magnesium in it within 1 hour before or 2 hours after you take misoprostol. If you miss a dose of misoprostol, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Ask your health care provider any questions you may have about how to use misoprostol ...
Use misoprostol as directed by your doctor. Check the label on the medicine for exact dosing instructions. An extra patient leaflet is available with misoprostol. Talk to your pharmacist if you have questions about this information. Take misoprostol by mouth with food unless your doctor tells you otherwise. The last dose of the day should be taken at bedtime. Taking misoprostol after meals and at bedtime may decrease the risk of diarrhea. Do not take an antacid that has magnesium in it within 1 hour before or 2 hours after you take misoprostol. If you miss a dose of misoprostol, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Ask your health care provider any questions you may have about how to use misoprostol ...
Use misoprostol as directed by your doctor. Check the label on the medicine for exact dosing instructions. An extra patient leaflet is available with misoprostol. Talk to your pharmacist if you have questions about this information. Take misoprostol by mouth with food unless your doctor tells you otherwise. The last dose of the day should be taken at bedtime. Taking misoprostol after meals and at bedtime may decrease the risk of diarrhea. Do not take an antacid that has magnesium in it within 1 hour before or 2 hours after you take misoprostol. If you miss a dose of misoprostol, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Ask your health care provider any questions you may have about how to use misoprostol ...
Use misoprostol as directed by your doctor. Check the label on the medicine for exact dosing instructions. An extra patient leaflet is available with misoprostol. Talk to your pharmacist if you have questions about this information. Take misoprostol by mouth with food unless your doctor tells you otherwise. The last dose of the day should be taken at bedtime. Taking misoprostol after meals and at bedtime may decrease the risk of diarrhea. Do not take an antacid that has magnesium in it within 1 hour before or 2 hours after you take misoprostol. If you miss a dose of misoprostol, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Ask your health care provider any questions you may have about how to use misoprostol ...
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In October 2017, the Chief Medical Officer and Health Secretary in Scotland recognised a womans home as a safe and acceptable place to take misoprostol, the second drug used to effect an early medical abortion. In early 2018, the Welsh Government announced that it would be following Scotlands lead. Today, the Cabinet Secretary for Health and Social Services in Wales has announced an agreement to allow misoprostol at home for medical abortion treatment.. In April 2018, the RCOG and FSRH signed a letter along with over twenty medical and womens groups calling on the Secretary of State for Health and Social Care to allow women in England to take misoprostol in a setting of their own choice. This letter, published in The Times, stated that this simple measure [..] would significantly improve the wellbeing of women.. The use of misoprostol at home is safe and is endorsed by the World Health Organization (WHO ...
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Misoprostol abortion pill, is one most commonly used and safe methods for medical abortion for early pregnancies (i.e. up to first 12 weeks of gestation period). Although Misoprostol has been quite effective for performing medical abortion, still it is considered beneficial to complete it by preceding the same with Mifepristone (or Mifeprex).
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The medical abortion normally causes side effects such as pain and cramping, as well as bleeding accompanied by the passage of blood clots and tissue. Nausea, vomiting, diarrhea, headache, dizziness, and hot flashes or fever may also occur.. A fever that starts soon after Misoprostol administration and lasts less than 24 hours and is less than 100.4 F/ 38 C is a common side effect. If the fever lasts longer than 24 hours or is greater than 100.4 F/38 C, you should seek medical attention.. An allergic reaction to the medication can cause hives (itchy welts or bumps on the skin.). If your side effects are extreme, you may have a complication. Please refer to the question How do you know if you have a complication and what should you do? if you think you might be experiencing abnormal side effects.. ...
The medical abortion normally causes side effects such as pain and cramping, as well as bleeding accompanied by the passage of blood clots and tissue. Nausea, vomiting, diarrhea, headache, dizziness, and hot flashes or fever may also occur.. A fever that starts soon after Misoprostol administration and lasts less than 24 hours and is less than 100.4 F/ 38 C is a common side effect. If the fever lasts longer than 24 hours or is greater than 100.4 F/38 C, you should seek medical attention.. An allergic reaction to the medication can cause hives (itchy welts or bumps on the skin.). If your side effects are extreme, you may have a complication. Please refer to the question How do you know if you have a complication and what should you do? if you think you might be experiencing abnormal side effects.. ...
The widespread use of NSAIDs has led to increased recognition of their adverse effects on the upper gastrointestinal tract. NSAIDs cause dyspepsia in many patients, and a small number develop clinically significant ulcers and complications. The prevention of adverse events from NSAIDs includes the use of low-risk agents and co-prescription with prostaglandins or acid inhibitors (1). The meta-analysis by Koch and colleagues examines the ability of H2 blockers and misoprostol to reduce NSAID-induced mucosal injury that was measured by endoscopy. This type of injury, which has uncertain clinical importance, was used as an outcome measure instead of more relevant outcomes, such as reduction in serious ulcer complications. As shown by this meta-analysis, misoprostol reduces both gastric and duodenal ulcers. More important, although misoprostol has been shown to reduce serious adverse events, the NNT is 264 to prevent a single complication (2). This leads us to consider whether misoprostol is ...
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We analysed data from an international prospective study on dietary and non-dietary predictors of pregnancy hormones and outcomes among women in Boston, United States, and Shanghai, China.1 Because the database of nutrients for the Chinese diet is incomplete, we present data on dietary intakes for the US women only.. Between March 1994 and October 1995, we identified 402 eligible pregnant women during their first routine prenatal visit at the Beth Israel Hospital in Boston and invited them to participate in the study. We followed throughout their pregnancies the 304 women who consented and did not have an early pregnancy termination or twin birth. The study population, study design, and methods have been described.1. We assessed dietary intake during the second trimester by using an extensive questionnaire on the frequency of eating, which is identical to the one used and validated in the nurses health study.2 Trained interviewers checked the questionnaire for accuracy and completeness before ...
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