Seattle, WA -- The InterVapor® Bronchoscopic Thermal Vapor Ablation (BTVA®) is back on the market after a brief hiatus as the asset sale of Uptake Medical Corporation was being completed to Broncus Holding Co. A new company, Uptake Medical Technology, Inc was formed in Seattle, WA, USA and has received a new CE Mark for the technology based on the clinically meaningful improvement in pulmonary function and quality of life for severe emphysema sufferers.¹ BTVA is now commercially available and patients are being treated in several European countries. Uptake Medical expects to expand global BTVA sales to Australia as well as Asian countries by the end of 2017.. "2018 promises to be an exciting year for the new Uptake Medical," says company founder and president Robert Barry, "with the recent outstanding STEP-UP multi-center randomized controlled trial results and the backing of Broncus, we are posed for success. In addition, we have very exciting bronchoscopic lung cancer ablation clinical ...
Men who have undergone a Transurethral Resection of the Prostate (TURP) for symptomatic lower urinary tract symptoms within 6 months. These patients may be included within the trial if deferred from consenting and screening until at least 6 months following the TURP ...
Berlin, Germany - Germanys Institute for Quality and Efficiency in Healthcare (IQWiG) recently published a commissioned study that assessed the available surgical and bronchoscopic lung volume reduction options for patients with severe pulmonary emphysema. Uptake Medicals recent randomized controlled trial (STEP-UP) of its Bronchoscopic Thermal Vapor Ablation (BTVA) InterVapor therapy was included in the German analysis.. The report included an analysis of patient relevant safety outcomes for each method analyzed. Of the bronchoscopic methods actively being used in Germany (vapor, EBV valves, IBV valves, and coils) vapor has the strongest safety profile. The comparison in Table 13 of the report concludes that coils and valves have "evidence [or] indication of harm to the treatment group as compared to the control group" in the category of "other adverse effects and complications of therapy." This is related to the high rates pneumothorax, hemoptysis, and other complications following ...
A assistant professor of Medicine in practice in North Carolina after a one week masters class has now begun to do ethanol ablation procedures in her practice. Recently did her first cyst treatment and now an ethanol ablation of a thyroid cancer neck lymph node. during the week she spent time training on a thyroid friendly radiofrequency ablation system RFA which is about to be released in the USA.. Call Matt at 310-393-8860 or [email protected] for Masters class details.. ...
Thyroid No Surgery 101: Ethanol Ablation PEI of Recurrent Symptomatic Benign Thyroid Cystic Nodule. A case Study:. 48 Y/O F with visible isthmus mass in the neck after prior drainage procedures was told she needed surgery and came to me for alternative therapy with Ethanol ablation PEI.Thyroid function was normal. and the pre-PEI FNA was benign.. ...
Irreversible electroporation, Liver resection, Minimally invasive pancreas surgery, Small bowel resection, Soft tissue ...tumor ablation, Cholecystectomy, Liver cyst removal, Laparoscopic surgery, Liver cyst fenestration, Cryoablation for cancer, Cancer treatment, Soft tissue sarcoma surgery, Bile duct stone removal, Splenectomy, Microwave ablation for cancer, Radiofrequency ablation for cancer, Pancreatectomy, Gastrectomy, Hepatobiliary disease evaluation, Hepatobiliary disease postoperative care, Portal hypertension management, Paracentesis, Pancreatic enucleation, Minimally invasive surgery, Minimally invasive intestinal surgery, Minimally invasive liver surgery, Whipple procedure, Liver tumor ablation, Bile duct resection, Bile duct injury, Polycystic liver disease, Peritoneal cancer, Idiopathic thrombocytopenic purpura, Bile duct stone, Pancreatic cancer, Pancreatitis, Biliary obstruction, Retroperitoneal sarcoma, Liver hemangioma, Pancreatic cyst, Small bowel cancer, Liver tumor, Bile duct ...
Alcohol septal ablation provides lasting relief for hypertrophic cardiomyopathy. Wake Forest Baptist is one of the few hospitals in NC that offers it.
SPARED Registry. This registry represents a multi-institutional effort to prospectively obtain real-world clinical data on prostate-sparing ablative devices including high-intensity focused ultrasound (HIFU), cryotherapy, focal laser ablation, irreversible electroporation, photodynamic therapy, and future technologies.. Background of the SPARED Registry. In light of the rapid adoption of novel but unproven technologies for prostate ablation, the need to monitor the safety and effectiveness in the post-market arena is essential. Following the recent approval of high-intensity focused ultrasound (HIFU) for ablation of prostate tissue, it is expected that more companies with novel technologies will apply for FDA clearance/approval. In light of the ever-expanding non-surgical options to treat prostate cancer, the MDEpiNet Science and Infrastructure Center at Weill Cornell, in collaboration with a multi-disciplinary group of stakeholders, has initiated the Study of Prostate Ablation Related Energy ...
TY - JOUR. T1 - Photothermal ablation of cancer cells using self-doped polyaniline nanoparticles. AU - Hong, Yoochan. AU - Cho, Wonseok. AU - Kim, Jeonghun. AU - Hwng, Seungyeon. AU - Lee, Eugene. AU - Heo, Dan. AU - Ku, Minhee. AU - Suh, Jin Suck. AU - Yang, Jaemoon. AU - Kim, Jung Hyun. PY - 2016/3/24. Y1 - 2016/3/24. N2 - Water-stable confined self-doping polyaniline nanocomplexes are successfully fabricated by nano-assembly using lauric acid both as a stabilizer and as a localized dopant. In particular, the colloidal stability of the polyaniline nanocomplexes in neutral pH and the photothermal potential by near-infrared light irradiation are characterized. We demonstrate that confined self-doping polyaniline nanocomplexes as a photothermal nanoagent are preserved in the doped state even at a neutral pH. Finally, confined self-doping polyaniline nanocomplexes aided by lauric acid are successfully applied for the photothermal ablation of cancer cells.. AB - Water-stable confined self-doping ...
This study will compare the efficacy and costs of four strategies of management of postoperative radioiodine ablation (levothyroxine sodium-withdrawal or
10. Multilateral action necessarily demands an organizational framework. The United Nations, in particular, is and should remain the primary venue for cooperation and coordination between nations, though regional forums have an important role to play in this regard as well. The United Nations is an imperfect institution, and many ideas for institutional reform have been mooted. Institutions, however, reflect the capacity of their members to work together. No state can expect that its policies will be accepted at all times by the community of nations. The UNs achievements are the result of the dedication of its major members, and its failures are due to lack of support by member states. Institutional changes in the United Nations are very unlikely to occur even in the medium term - the urgent and central task of todays leaders must be to work effectively with the organizations that exist and the tools at hand. The vital role of the Security Council remains central to todays international ...
HALIFAX - Canada is going through an unprecedented period of unilateral decision making by Prime Minister Stephen Harpers government and it has Canadas premiers worried, says Quebec Premier Jean Charest.. Charest, a veteran politician whose elected political career goes back to former Conservative Prime Minister Brian Mulroneys government, said he could not remember a period marked by more unilateral decisions on the part of Ottawa.. "We are in a period of unilateralism on the federal governments part," said Charest, who is expected to call a Quebec election in coming days. "This is a period of unilateralism and that preoccupies every single premier.". "None of us have experienced a period in which the federal government has made so many decisions that affect our citizens in areas where we each have a role to play, where the federal government has made unilateral decisions.". Charest said it began in 2007 with the budget on equalizations and transfer payments then when the financing was ...
Effect of 1.11/1.85 versus 3.7 GBq iodine-131 under rhTSH stimulation on thyroid remnant ablation rate according to diagnostic scans. CI, confidence interval; r
The prostatic urethral lift (Urolift) versus the thermal water vapor ablation (Rezūm) for minimally invasive treatment of BPH: a comparison of improvements and durability in 3-year clinical ...
This intensive and highly focused three-day symposium brings together the worlds leading medical scientists to share in a highly interactive environment the most recent advances in the field of atrial fibrillation. The primary objective of the meeting is to provide attendees with a thorough and practical view of the current state of the art in the field of AF in a scholarly and collegial atmosphere.
This intensive and highly focused three-day symposium brings together the worlds leading medical scientists to share in a highly interactive environment the most recent advances in the field of atrial fibrillation. The primary objective of the meeting is to provide attendees with a thorough and practical view of the current state of the art in the field of AF in a scholarly and collegial atmosphere.
Bogdanov AA, Gupta S, Koshkina N, Corr SJ, Zhang S, Curley SA, Han G. Gold nanoparticles stabilized with MPEG-grafted poly(l-lysine): in vitro and in vivo evaluation of a potential theranostic agent. Bioconjug Chem. 2015 Jan 21; 26(1):39-50 ...
ASTRO 2019 study finds a single dose image-guided cardiac radioablation dramatically reduces episodes of fast, abnormal heartbeats for more than two years.
A volumetric tissue ablation apparatus includes a probe having a plurality of wires journaled through a catheter with a proximal end connected to the active terminal of a generator and a distal end projecting from a distal end of the catheter. The probe wire distal ends are arranged in an array with the distal ends located generally radially and uniformly spaced-apart from the catheter distal end. A conductor connected to the return terminal of the generator is located relative to the probe wire array to form a closed electrical circuit through tissue to be ablated. Preferably, the probe wire array includes 10 wires, each formed in an arch from the catheter distal end. The conductor can be either a conventional ground plate upon which the tissue is supported, or a conductor wire extending through the probe and electrically insulated from the probe wires.
Xu, Wei; Luo, Feng Tao; Wang, Quan; Tan, Qiao Yan; Huang, Ju Nlan; Zhou, Si Ru; Wang, Zu Qiang; Sun, Xiand Ding; Kuang, Liang; Jin, Min; Su, Nan; Jiang, Wan Ling; Chen, Liang; Qi, Hua Bing; Zhu, Ying; Chen, Bo; Chen, Han Gang; Chen, Shuai; Gao, Yu; Xu, Xiao Ling; Deng, Chu Xia; Chen, Lin; Xie, Yang Li; Du, Xiao Lan, Inducible activation of FGFR2 in adult mice promotes bone formation after bone marrow ablation. Journal Of Bone And Mineral Research 2017 ...
The French Figure Skating Championships (French: Championnat de France Elite) is a figure skating national championship held annually to determine the national champions of France. Skaters compete at the senior level in the disciplines of mens singles, womens singles, pair skating, ice dancing, and synchronized skating. The 2005-2006 competition took place between December 9th and 11th, 2005 in Besançon. The event was used to help determine the French team to the 2006 European Figure Skating Championships, the 2006 World Figure Skating Championships and the 2006 Winter Olympic Games. ...
Other Inquire More and Share Questions If Any Before the Purchase on This Report At: www.absolutereports.com/enquiry/pre-order-enquiry/13903159 This report also splits the market by region: Americas- United States, Canada, Mexico, Brazil, APAC, China, Japan, Korea, Southeast Asia, India, Australia, Europe, Germany, France, UK, Italy, Russia, Spain, Middle East & Africa, Egypt, South Africa, Israel, Turkey, GCC Countries. Detailed TOC of Global Irreversible Electroporation Ablators Market Growth 2019-2024. 1 Scope of the Report. 1.1 Market Introduction. 1.2 Research Objectives. 1.3 Years Considered. 1.4 Market Research Methodology. 1.5 Economic Indicators. 1.6 Currency Considered. 2 Executive Summary. 2.1 World Market Overview. 2.2 Irreversible Electroporation Ablators Segment by Type. 2.3 Irreversible Electroporation Ablators Consumption by Type. 2.4 Irreversible Electroporation Ablators Segment by Application. 2.5 Irreversible Electroporation Ablators Consumption by Application. 3 Global ...
A new method for the ablation of undesirable tissue such as cells of a cancerous or non-cancerous tumor is disclosed. It involves the placement of electrodes into or near the vicinity of the undesirable tissue through the application of electrical pulses causing irreversible electroporation of the cells throughout the entire area of the undesirable tissue. The electric pulses irreversibly permeate the cell membranes, thereby invoking cell death. The irreversibly permeabilized cells are left in situ and are removed by the body immune system. The amount of tissue ablation achievable through the use of irreversible electroporation without inducing thermal damage is considerable.
To report on the first short-term oncologic outcomes of percutaneous irreversible electroporation for small renal masses.Patients with cT1a renal masses treated with irreversible electroporation from April 2013 through December 2016 were reviewed.
Irreversible electroporation is a minimally invasive technique for the non-thermal destruction of cells in a targeted volume of tissue, using brief electric pulses, (~100 µs long) delivered through electrodes placed into or around the targeted region. These electric pulses destabilize the integrity of the cell membrane, resulting in the creation of nanoscale defects that increase a cells permeability to exchange with its environment. When the energy of the pulses is high enough, the cell cannot recover from these effects and dies in a non-thermal manner that does not damage neighboring structures, including the extracellular matrix. IRE has been shown to spare the major vasculature, myelin sheaths, and other supporting tissues, permitting its use in proximity to these vital structures. This technique has been proposed to be harnessed as an advantageous non-thermal focal ablation technique for diseased tissues, including tumors. IRE electric pulses may be delivered through small (ø ≈ 1 mm) ...
Irreversible electroporation (IRE), a new tissue ablation procedure available since 2007, could meet the requirements for ideal focal therapy of …
PurposeNumerical simulations are used for treatment planning in clinical applications of irreversible electroporation (IRE) to determine ablation size and shape. To assess the reliability of simulations for treatment planning, we compared simulation results with empiric outcomes of renal IRE using computed tomography (CT) and histology in an animal model.MethodsThe ablation size and shape for six different IRE parameter sets (70-90 pulses, 2,000-2,700 V, 70-100 µs) for monopolar and bipolar electrodes was simulated using a numerical model. Employing these treatment parameters, 35 CT-guided IRE ablations were created in both kidneys of six pigs and followed up with CT immediately and after 24 h. Histopathology was analyzed from postablation day 1.ResultsAblation zones on CT measured 81 ± 18 % (day 0, p ≤ 0.05) and 115 ± 18 % (day 1, p ≤ 0.09) of the simulated size for monopolar electrodes, and 190 ± 33 % (day 0, p ≤ 0.001) and 234 ± 12 % (day 1, p ≤ 0.0001) for bipolar electrodes. ...
Ablation Technologies Market by Product (Radiofrequency, Ultrasound, Irreversible Electroporation, Cryotherapy, Microwave), Application (General & Cosmetic Surgery, Cardiovascular, Cancer, Ophthalmology, Orthopedics) - Global Forecasts to 2019 - Market research report and industry analysis - 8399979
Read "Intracranial Nonthermal Irreversible Electroporation: InVivo Analysis, The Journal of Membrane Biology" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
Nanoknife - irreversible electroporation blijkt succesvolle operatietechniek te zijn bij lokaal uitgezaaide alvleesklierkanker. Slechts 6 patiënten (3%) kreeg recidief op 2,5 jaar meting. Mediane overleving nu al 24.9 maanden (range 4.9-85 maanden). Artikel update 8 mei 2019
Exposing a biological cell to an electric field results in structural changes in the cell plasma membrane. If the electric field is sufficiently high, the changes in the trans-membrane voltage cause the membrane to become permeable to molecules which otherwise cannot cross it. The described phenomenon is termed electroporation [1] and can be either reversible or irreversible. If the electric field at given pulse characteristics exceeds the reversible electroporation threshold, the cell eventually returns to its normal state and survives; this is called reversible electroporation. However, if the electric field exceeds the threshold of irreversible electroporation or the cell is exposed to the electric field too long, the changes in the membrane lead to irreversible electroporation (IRE) characterized by cell death.. Both reversible and irreversible electroporation have found their use in treatment of tumors [2]. Combination of reversible electroporation and cytotoxic drugs used in chemotherapy ...
A method and device are herein described to treat a target region of tissue, using at least one energy delivery device coupled to a power source and positioned in a treatment position so as to irreversibly electroporate tissue to ablate a target region, and introduce regenerative materials into a treated region.
Specifications Location Function types Scientific fields Hours Salary Education Job number About employer Enschede PhD positions Natural Sciences, Engineering, ...
SALT LAKE CITY--(BUSINESS WIRE)--Apr 9, 2012-- BSD Medical Corporation (NASDAQ:BSDM) (Company or BSD) (www.BSDMedical.com), a leading provider of medical systems that utilize heat therapy to treat cancer, announced today that the Company has sold an additional MicroThermX(R) Microwave Ablation System (MicroThermX(R)) to Synapse Medical Ltd.. Synapse Medical is a premier specialty distributor of medical devices in Ireland and Northern Ireland, and is an exclusive distributor for a number of leading medical device companies, including BSD. Synapse is a subsidiary of SISK Healthcare, which is part of the SISK Group. The SISK Group was established in 1859 and has annual revenues in excess of ?1 billion.. About the MicroThermX (R) Microwave Ablation System The MicroThermX(R) is a compact, mobile, state-of-the-art, proprietary system that includes a microwave generator, single-patient-use disposable antennas and a thermistor-based temperature monitoring system. The innovative design of the ...
The present retrospective study aimed to investigate the mid‑term safety and efficacy of hepatectomy combined with microwave ablation of the partial spleen for treatment of liver cancer complicated with hypersplenism. A retrospective analysis was performed on 23 patients who underwent hepatectomy combined with microwave ablation of the partial spleen for liver cancer, complicated with hypersplenism that was secondary to cirrhosis. The splenic and ablated volumes were calculated according to a contrast‑enhanced computed tomography scan prior to and 2 weeks after the operation. Complete blood count and liver function tests were examined prior to and following the surgery, and complications and changes in the blood tests were monitored for 6 months. Over this period of investigation, the splenic volume was reduced by a mean value of 34.0%. The levels of serum alanine aminotransferase and aspartate aminotransferase were increased on the first day after the operation ( ...
Sonacare Medical. The report studies the industry for Tumor Ablation across the globe taking the existing industry chain, the import and export statistics in Tumor Ablation market & dynamics of demand and supply of Tumor Ablation into consideration. The Tumor Ablation research study covers each and every aspect of the Tumor Ablation market globally, which starts from the definition of the Tumor Ablation industry and develops towards Tumor Ablation market segmentations. Further, every segment of the Tumor Ablation market is classified and analyzed on the basis of product types, application, and the end-use industries of the Tumor Ablation market. The geographical segmentation of the Tumor Ablation industry has also been covered at length in this report.. The competitive landscape of the worldwide market for Tumor Ablation is determined by evaluating the various industry participants, production capacity, Tumor Ablation markets production chain, and the revenue generated by each manufacturer in ...
The selective infusion of ethanol into the coronary circulation supplying the site of origin of incessant ventricular tachycardia has been demonstrated to abolish this arrhythmia in selected patients. The present study was designed to evaluate the efficacy and safety of the intracoronary ethanol ablation technique in patients with paroxysmal ventricular tachycardia related to prior myocardial infarction. Twenty-three patients with sustained monomorphic ventricular tachycardia that was refractory to conventional antiarrhythmic drug therapy were prospectively studied. After induction of ventricular tachycardia by programmed electrical stimulation, the response of the arrhythmia to the infusion of radiographic contrast medium or saline solution into the ostia of the native coronary arteries and coronary artery bypass grafts was assessed. If ventricular tachycardia was reliably interrupted by injections into the proximal coronary artery or bypass graft, the vessel was cannulated with a steerable guide wire
A microwave ablation instrument including a transmission line having a first conductor and a second conductor suitable for the transmission of microwave energy. A horn antenna device is mounted to the end of the transmission line, and include an outer conductor and an inner conductor. The outer conductor of the horn antenna is electrically coupled to the second conductor of the transmission line, and includes a peripherally extending interior wall flaring outwardly to define a recess therein. The inner conductor of the horn antenna is electrically coupled to the first conductor of the transmission line and terminates in the outer conductor recess. The inner conductor and the outer conductor cooperate to emit an electromagnetic field sufficiently strong to cause tissue ablation in a direction generally away from the flared interior wall of the outer conductor.
PURPOSE: To evaluate preliminary outcomes after microwave ablation (MWA) of hepatocellular carcinoma (HCC) up to 5 cm and to determine the influence of tumor size. MATERIALS AND METHODS: Electronic records were searched for HCC and MWA. Between January 2011 and September 2014, 173 HCCs up to 5 cm were treated by MWA in 129 consecutive patients (89 men, 40 women; mean age, 66.9 y ± 9.5). Tumor characteristics related to local tumor progression and primary and secondary treatment efficacy were evaluated by univariate analysis. Outcomes were compared between tumors ≤ 3 cm and tumors | 3 cm. RESULTS: Technical success, primary efficacy, and secondary efficacy were 96.5%, 99.4%, and 94.2% at a mean follow-up period of 11.8 months ± 9.8 (range, 0.8-40.6 mo). Analysis of tumor characteristics showed no significant risk factor for local tumor progression, including subcapsular location (P = .176), tumor size (P = .402), and perivascular tumor location (P = .323). The 1-year and 2-year secondary or overall
microwave ablation on advanced medical technologies | Below is a table with a list of the market segments demonstrating greater than 10% compound annual…
Microwave ablation (MWA) therapy cut pain in half for patients with painful bone and soft-tissue tumors, new research has suggested.
Vivant Medical has announced an ongoing investigational study to determine the effectiveness of microwave ablation for treatment of liver cancers. The stud
A quick reference on Obstructive hypertrophic cardiomyopathy, covering the clinical presentation, investigative approach, and key principles of management
The aim of the study is the evaluation of the ablation efficiency of the percutaneous irreversible electroporation (IRE) as primary ablation therapy of locally...
To investigate the reliability of simulations for planning pancreatic irreversible electroporation (IRE) ablations compared with computed tomography (CT) and pathology outcomes in an animal model. Simulations were performed varying treatment parameters, including field strength (1.5-2.5 kV/cm), p...
Methods and apparatus are provided for treatment of heart arrhythmia via renal neuromodulation. Such neuromodulation may effectuate irreversible electroporation or electrofusion, ablation, necrosis a
Trial Design. Pancreatic cancer resectability is defined by the absence of metastases and only limited invasion of arteries (SMA, common hepatic artery, celiac trunk) and veins (superior mesenteric vein / portal vein) (Katz et al. 2013, Ann Surg Oncol 20:2787). Only Stage III pancreatic cancer (AJCC - TNM 7th edition) will be enrolled in the study. All cases will be reviewed at the multidisciplinary meeting to confirm eligibility. After obtaining their informed consent patients will receive 4 cycles of FOLFIRINOX chemotherapy. Following reassessment, patients without progression will proceed to local treatment. Diagnostic laparoscopy will be performed to exclude distant metastases. Unresectable tumors up to 4cm will be randomized between stereotactic body radiotherapy (SBRT) (Arm A) versus irreversible electroporation (IRE) (Arm B). Tumors larger than 4cm will be randomized to chemo-radiation (Intensity modulated radiation therapy: 28 × 2Gy = 56 Gy to the primary tumor and metastatic lymph ...
Cellulose nanocrystals (CNCs) have been studied widely for a variety of applications. Despite their advantages, investigations of their abilities in the biomedical field have not been explored. The goal of this project is to delve into the potential uses of CNCs in detection, targeted drug delivery, and potentiation of irreversible electroporation (IRE)-induced cell death in folate receptor (FR)-positive cancers. To accomplish this task we have prepared stable and reproducible CNCs from wood pulp via sulfuric acid hydrolysis. Furthermore, we have functionalized the surface of these nanoparticles and conjugated them with the targeting ligand folic acid (FA) and the fluorescent imaging agent fluorescein-5\-isothiocyanate (FITC) to create FITC-CNC-FA; CNCs have also been conjugated with doxorubicin (DOX), a potent chemotherapeutic (DOX-ALAL-CNC-FA). We have determined FITC-CNC-FA\s and DOX-ALAL-CNC-FA\s ability to specifically target FR-positive cancer cells in vitro; meanwhile non-targeted CNCs ...
nexavar online cheap taking the oral vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors (TKIs) sorafenib and sunitinib for renal cell carcinoma (RCC) had a significantly elevated danger for cardiovascular events, significantly stroke, in accordance with the outcomes of a study published not too long ago in Cancer. Strati﫿cation for sufferers with hepatocellular carcinoma. Irreversible electroporation, utilizing the NanoKnife, is a new therapy for liver most cancers that is administered by radiologists. In a commentary revealed final yr, a group of physicians decried the cost of this drug, particularly for the reason that Nationwide Institutes of Well being and Cystic Fibrosis Foundation helped help its development (JAMA ...
PET scans of lung tumor near airway before (left) and 3 months after (right) irreversible electroporation treatment (credit: Constantinos Sofocleous, Memorial