1-acyl-sn-glycerol-3-phosphate acyltransferase alpha | definition of 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha by...
Looking for online definition of 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha in the Medical Dictionary? 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha explanation free. What is 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha? Meaning of 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha medical term. What does 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha mean?
1-acyl-sn-glycerol-3-phosphate acyltransferase beta | definition of 1-acyl-sn-glycerol-3-phosphate acyltransferase beta by...
Looking for online definition of 1-acyl-sn-glycerol-3-phosphate acyltransferase beta in the Medical Dictionary? 1-acyl-sn-glycerol-3-phosphate acyltransferase beta explanation free. What is 1-acyl-sn-glycerol-3-phosphate acyltransferase beta? Meaning of 1-acyl-sn-glycerol-3-phosphate acyltransferase beta medical term. What does 1-acyl-sn-glycerol-3-phosphate acyltransferase beta mean?
A Plant Acyltransferase Involved in Triacylglycerol Biosynthesis Complements an Escherichia Coli sn-1-acylglycerol-3-phosphate...
The second acylation reaction in glycerolipid biosynthesis is catalyzed by an sn-1-acylglycerol-3-phosphate acyltransferase. The enzyme of Limnanthes douglusii involved in triacylglycerol synthesis has an unusual specificity for very long chain acyl groups in both of its substrates, namely acyl-CoA and sn-1-acylglycerol-3-phosphate, and causes the enrichment of erucoyl groups in the sn-2 position of the seed oil of this plant species. We have isolated a cDNA clone encoding this embryo-specific, microsomal acyltransferase via heterologous complementation of an Escherichia coli mutant deficient in sn -1-acyl-glycerol-3-phosphate acyltransferase activity. The open reading frame of the cDNA insert encodes a protein with a length of 281 amino acids, with three predicted membrane-spanning domains and of about 31.7 kDa. The sequence exhibits substantial sequence similaritiy to the sn-1-acylglycerol-3-phosphate acyltransferase of E. coli. The corresponding transcript was detectable in developing embryos ...
Human Metabolome Database: HMDBP11598 (1-acylglycerol-3-phosphate O-acyltransferase ABHD5) Metabolite Associations
This project is supported by the Canadian Institutes of Health Research (award #111062), Alberta Innovates - Health Solutions, and by The Metabolomics Innovation Centre (TMIC), a nationally-funded research and core facility that supports a wide range of cutting-edge metabolomic studies. TMIC is funded by Genome Alberta, Genome British Columbia, and Genome Canada, a not-for-profit organization that is leading Canadas national genomics strategy with $900 million in funding from the federal government ...
Human Metabolome Database: Showing Protein 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (HMDBP11598)
This project is supported by the Canadian Institutes of Health Research (award #111062), Alberta Innovates - Health Solutions, and by The Metabolomics Innovation Centre (TMIC), a nationally-funded research and core facility that supports a wide range of cutting-edge metabolomic studies. TMIC is funded by Genome Alberta, Genome British Columbia, and Genome Canada, a not-for-profit organization that is leading Canadas national genomics strategy with $900 million in funding from the federal government ...
GTOP nfar0:BAD56558.1
GT:ID BAD56558.1 GT:GENE BAD56558.1 GT:PRODUCT putative 1-acylglycerol-3-phosphate O-acyltransferase GT:DATABASE GIB00210CH01 GT:ORG nfar0 GB:ACCESSION GIB00210CH01 GB:LOCATION complement(1863574..1864296) GB:FROM 1863574 GB:TO 1864296 GB:DIRECTION - GB:PRODUCT putative 1-acylglycerol-3-phosphate O-acyltransferase GB:PROTEIN_ID BAD56558.1 LENGTH 240 SQ:AASEQ MFYWLLKFVLVGPFIRVYNRPTVEGVENIPSDGPAILAGNHLSIADWLFAPLLSPRRINYLAKAEYFTTPGIKGRLQKFFFSGTGQYPIDRSGADAAEDALNAARKLLDQGKLVGLYPEGTRSPDGRLYKGKTGMARLALETGVPVIPVAVIGTDKVAPPGPFRWRRHKVTVKFGAPIDFSRYEGMGGNRFVERAVTDEVMYELMRLSGQEYVDVYAHSLKGVPSGSKPEAPRIPDTAAS GT:EXON 1,1-240:0, BL:SWS:NREP 1 BL:SWS:REP 9-,161,LPAT1_ARATH,2e-17,35.7,143/356, SEG 94-,104,adaaedalnaa, RP:PFM:NREP 1 RP:PFM:REP 23-,152,PF01553,5e-18,42.4,125/132,Acyltransferase, HM:PFM:NREP 1 HM:PFM:REP 21-,151,PF01553,1.2e-31,45.2,126/135,Acyltransferase, GO:PFM:NREP 2 GO:PFM GO:0008152,GO:metabolic process,PF01553,IPR002123, GO:PFM GO:0008415,GO:acyltransferase activity,PF01553,IPR002123, ...
AN1 LOCUS6543 - 1-acylglycerol-3-phosphate O-acyltransferase - Arabidopsis thaliana (Mouse-ear cress) - AN1 LOCUS6543 gene &...
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class=publication>Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href=http://www.nrbook.com/b/bookcpdf.php>Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
AGPAT2 - Wikipedia
1-acyl-sn-glycerol-3-phosphate acyltransferase beta is an enzyme that in humans is encoded by the AGPAT2 gene. This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. GRCh38: Ensembl release 89: ENSG00000169692 - Ensembl, May 2017 GRCm38: Ensembl release 89: ENSMUSG00000026922 - Ensembl, May 2017 Human PubMed Reference:. Mouse PubMed Reference:. Eberhardt C, Gray PW, Tjoelker LW (Aug 1997). Human lysophosphatidic acid acyltransferase. cDNA cloning, expression, and localization to chromosome 9q34.3. The Journal of ...
CGI-58 facilitates the mobilization of cytoplasmic triglyceride for lipoprotein secretion in hepatoma cells<...
TY - JOUR. T1 - CGI-58 facilitates the mobilization of cytoplasmic triglyceride for lipoprotein secretion in hepatoma cells. AU - Brown, J. Mark. AU - Chung, Soonkyu. AU - Das, Akash. AU - Shelness, Gregory S.. AU - Rudel, Lawrence L.. AU - Yu, Liqing. PY - 2007/10. Y1 - 2007/10. N2 - Comparative Gene Identification-58 (CGI-58) is a member of the α/β-hydrolase family of proteins. Mutations in the human CGI-58 gene are associated with Chanarin-Dorfman syndrome, a rare autosomal recessive genetic disease in which excessive triglyceride (TG) accumulation occurs in multiple tissues. In this study, we investigated the role of CGI-58 in cellular lipid metabolism in several cell models and discovered a role for CGI-58 in promoting the packaging of cytoplasmic TG into secreted lipoprotein particles in hepatoma cells. Using both gain-of-function and loss-of-function approaches, we demonstrate that CGI-58 facilitates the depletion of cellular TG stores without altering cellular cholesterol or ...
OriGene - Agpat1 (NM 018862) Human ORF cDNA Clone
Agpat1 - Agpat1 (Myc-DDK-tagged) - Mouse 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) (Agpat1), transcript variant 2 available for purchase from OriGene - Your Gene Company.
OriGene - AGPAT2 (NM 001012727) Human ORF cDNA Clone
AGPAT2 - AGPAT2 (GFP-tagged) - Human 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) (AGPAT2), transcript variant 2 available for purchase from OriGene - Your Gene Company.
AGPAT2 - 1-acyl-sn-glycerol-3-phosphate acyltransferase - Homo sapiens (Human) - AGPAT2 gene & protein
Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
WikiGenes - AGPAT9 - 1-acylglycerol-3-phosphate O...
The worlds first wiki where authorship really matters. Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts.
Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase (P33333) - Yeast Metabolome Database
Jacq, C., Alt-Morbe, J., Andre, B., Arnold, W., Bahr, A., Ballesta, J. P., Bargues, M., Baron, L., Becker, A., Biteau, N., Blocker, H., Blugeon, C., Boskovic, J., Brandt, P., Bruckner, M., Buitrago, M. J., Coster, F., Delaveau, T., del Rey, F., Dujon, B., Eide, L. G., Garcia-Cantalejo, J. M., Goffeau, A., Gomez-Peris, A., Zaccaria, P., et, a. l. .. (1997). The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. Nature 387:75-78.9169867 ...
EMBL: CP001600.PE179
CP001600.PE179 Location/Qualifiers FT CDS_pept 207513..208256 FT /codon_start=1 FT /transl_table=11 FT /locus_tag=NT01EI_0204 FT /product=1-acyl-sn-glycerol-3-phosphate acyltransferase, FT putative FT /EC_number=2.3.1.51 FT /db_xref=EnsemblGenomes-Gn:NT01EI_0204 FT /db_xref=EnsemblGenomes-Tr:ACR67447 FT /db_xref=GOA:C5B6Y5 FT /db_xref=InterPro:IPR002123 FT /db_xref=InterPro:IPR004552 FT /db_xref=UniProtKB/TrEMBL:C5B6Y5 FT /protein_id=ACR67447.1 FT /translation=MLFIFRVILITLLCLVICIVGSLYCLFSPRNPRHVARFGHWFGRL FT SPLFGLKVETRLPPDAATYGNAIYIANHQNNYDMVTASNAVQPNTVTVGKKSLAWIPFF FT GQLYWLTGNLLIDRKNRTKAHNTIAAVVEQFRTRRISFWMFPEGTRSRGRGLMPFKTGA FT FHAALAAGVPIVPICVSSTHDKVKLNRWNNGVVIVEMLPPIDTSRWGKDQVRDLAEHCR FT TLMAEKIGQLDAEVAAREAQAGKRA atgctattca ttttccgggt catactgatc acgttgctgt gcctcgtcat ctgcattgtc 60 ggttcgctgt attgcctgtt cagcccgcgc aacccgcgcc acgtcgcgcg ttttggccac 120 tggttcggcc gcttatcgcc gctgtttggc ctgaaggttg aaacgcgcct gccgccggat 180 gccgcaacct atggcaacgc catctatatc gccaaccacc ...
protein groups list
PLCD-like protein of unknown function with low similarity to 1-acyl-sn-glycerol-3-phosphate acyltransferase delta, chloroplast precursor ...
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Recombinant Human AGPAT2 293 Cell Lysate AGPAT2-8977HCL - Creative BioMart
Purified Recombinant Human AGPAT2 293 Cell Lysate from Creative Biomart. Recombinant Human AGPAT2 293 Cell Lysate can be used for research.
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Bovine AGPAT6 ELISA KIT
Bovine AGPAT6 ELISA KIT allows for the in vitro quantitative determination of Bovine AGPAT6 concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids.
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Recombinant Human ABHD2 protein, MYC/DDK-tagged ABHD2-4893H - Creative BioMart
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ABHD5 Gene - GeneCards | ABHD5 Protein | ABHD5 Antibody
Complete information for ABHD5 gene (Protein Coding), Abhydrolase Domain Containing 5, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium
AGPAT1抗体|Abcam中国|Anti-AGPAT1抗体
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TumorPortal
This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized ...
Mutagenesis of a plastidial lysophosphatidic acid acyltransferase | Biochemical Society Transactions
A combination of site-directed and random mutagenesis generated sequence variants of a plastidial lysophosphatidic acid acyltransferase. Alanine substitutions of residues present within two conserved motifs including the putative catalytic histidine resulted in a loss of acyltransferase activity assessed as complementation competance. Substitutions at five sites within the central core resulted in reduced or loss of activity. Truncation mutants reveal that sequences in the C-terminal moiety are essential for function.. ...
Defective Lipolysis and Altered Energy Metabolism in Mice Lacking Adipose Triglyceride Lipase | Science
Fat tissue is the most important energy depot in vertebrates. The release of free fatty acids (FFAs) from stored fat requires the enzymatic activity of lipases. We showed that genetic inactivation of adipose triglyceride lipase (ATGL) in mice increases adipose mass and leads to triacylglycerol deposition in multiple tissues. ATGL-deficient mice accumulated large amounts of lipid in the heart, causing cardiac dysfunction and premature death. Defective cold adaptation indicated that the enzyme provides FFAs to fuel thermogenesis. The reduced availability of ATGL-derived FFAs leads to increased glucose use, increased glucose tolerance, and increased insulin sensitivity. These results indicate that ATGL is rate limiting in the catabolism of cellular fat depots and plays an important role in energy homeostasis.. ...
New Atglistatin closely related analogues: Synthesis and structure-activity relationship towards adipose triglyceride lipase...
New Atglistatin closely related analogues: Synthesis and structure-activity relationship towards adipose triglyceride lipase inhibition
eCite - Phosphorylation of adipose triglyceride lipase Ser(404) is not related to 5-AMPK activation during moderate-intensity...
Phosphorylation of adipose triglyceride lipase Ser(404) is not related to 5-AMPK activation during moderate-intensity exercise in humans
Sterol O-Acyltransferase financial definition of Sterol O-Acyltransferase
Definition of Sterol O-Acyltransferase in the Financial Dictionary - by Free online English dictionary and encyclopedia. What is Sterol O-Acyltransferase? Meaning of Sterol O-Acyltransferase as a finance term. What does Sterol O-Acyltransferase mean in finance?
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Search Results
Numerous hits in gapped BLAST to probable 1-acyl-sn-glycerol-3-phosphate acyltransferases, e.g. residues 3-253 are 32% similar to PLSC_MYCGE (MG212). Apart from the similarities to mycoplasma proteins, BLAST scores are below 100 due to the lack of similarity over the NH-terminal residues. No significant similarity to T.pallidum or C.trachomatis ...
Phosphatidylcholine-sterol o-acyltransferase: Definition with Phosphatidylcholine-sterol o-acyltransferase Pictures and Photos
Definition of Phosphatidylcholine-sterol o-acyltransferase with photos and pictures, translations, sample usage, and additional links for more information.
ABHD4 regulates multiple classes of N-acyl phospholipids in the mammalian central nervous system
N-Acyl phospholipids are atypical components of cell membranes that bear three acyl chains and serve as potential biosynthetic precursors for lipid mediators such as endocannabinoids. Biochemical studies have implicated ABHD4 as a brain N-acyl phosphatidylethanolamine (NAPE) lipase, but in vivo evidence for this functional assignment is lacking. Here, we describe ABHD4(-/-) mice and their characterization using untargeted lipidomics to discover that ABHD4 regulates multiple classes of brain N-acyl phospholipids. In addition to showing reductions in brain glycerophospho-NAEs (GP-NAEs) and plasmalogen-based lyso-NAPEs (lyso-pNAPEs), ABHD4(-/-) mice exhibited decreases in a distinct set of brain lipids that were structurally characterized as N-acyl lysophosphatidylserines (lyso-NAPSs). Biochemical assays confirmed that NAPS lipids are direct substrates of ABHD4. These findings, taken together, designate ABHD4 as a principal regulator of N-acyl phospholipid metabolism in the mammalian nervous system ...
Cardiomyocyte steatosis and defective washout of iodine-123-β-methyl iodophenyl-pentadecanoic acid in genetic deficiency of...
TY - JOUR. T1 - Cardiomyocyte steatosis and defective washout of iodine-123-β-methyl iodophenyl-pentadecanoic acid in genetic deficiency of adipose triglyceride lipase. AU - Hirano, Ken Ichi. AU - Ikeda, Yoshihiko. AU - Sugimura, Koichiro. AU - Sakata, Yasuhiko. PY - 2015/3/1. Y1 - 2015/3/1. UR - http://www.scopus.com/inward/record.url?scp=84924402434&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=84924402434&partnerID=8YFLogxK. U2 - 10.1093/eurheartj/ehu417. DO - 10.1093/eurheartj/ehu417. M3 - Comment/debate. C2 - 25336228. AN - SCOPUS:84924402434. VL - 36. SP - 580. JO - European Heart Journal. JF - European Heart Journal. SN - 0195-668X. IS - 9. ER - ...
ABHD12 cdna clone product blog
Blog on ABHD12 cdna clone product: The ABHD12 abhd12 (Catalog #MBS1276747) is a cDNA Clone and is intended for research purposes only. The p...
AbnovaHuman AGPAT1 Full-length ORF (NP 006402.1, 1 a.a. - 283 a.a.) Recombinant | Fisher Scientific
Human AGPAT1 Full-length ORF (NP_006402.1, 1 a.a. - 283 a.a.) Recombinant Protein with GST-tag at N-terminal, Abnova; For use in AP, Array, ELISA, WB-Re Shop Abnova™ Human
ABHD9 polyclonal antibody - (PAB21930) - Products - Abnova
Rabbit polyclonal antibody raised against recombinant ABHD9. Recombinant protein corresponding to amino acids of human ABHD9. (PAB21930) - Products - Abnova
Tissue expression of ABHD12 - Staining in kidney - The Human Protein Atlas
Expression of ABHD12 (ABHD12A, BEM46L2, C20orf22, dJ965G21.2, DKFZP434P106) in kidney tissue. Antibody staining with HPA026866 in immunohistochemistry.
Expression of ABHD17B in cancer - Summary - The Human Protein Atlas
Expression of ABHD17B (C9orf77, CGI-67, FAM108B1) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers.
Mutation in the ABHD12 Gene Causes & Reasons - Symptoma
Mutation in the ABHD12 Gene Symptom Checker: Possible causes include Usher Syndrome Type 3B. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.
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