Saccharomycetales
Electron Transport Complex I
Yeasts
Peroxisomes
Alkanes
Batch Cell Culture Techniques
Oleic Acid
Molecular Sequence Data
Adaptation to salt stress in a salt-tolerant strain of the yeast Yarrowia lipolytica. (1/172)
We have studied the cellular mechanisms underlying adaptation to salt stress in a newly isolated osmo- and salt-tolerant strain of the yeast Yarrowia lipolytica. When cells are incubated in the presence of 9% NaCl, a rapid change in their size and shape is observed. Salt stress is accompanied by an increase in the intracellular level of glycerol, free amino acids (notably proline and aliphatic amino acids), and Na+, as well as by changes in lipid and fatty acid composition. (+info)Yarrowia lipolytica Pex20p, Saccharomyces cerevisiae Pex18p/Pex21p and mammalian Pex5pL fulfil a common function in the early steps of the peroxisomal PTS2 import pathway. (2/172)
Import of peroxisomal matrix proteins is essential for peroxisome biogenesis. Genetic and biochemical studies using a variety of different model systems have led to the discovery of 23 PEX genes required for this process. Although it is generally believed that, in contrast to mitochondria and chloroplasts, translocation of proteins into peroxisomes involves a receptor cycle, there are reported differences of an evolutionary conservation of this cycle either with respect to the components or the steps involved in different organisms. We show here that the early steps of protein import into peroxisomes exhibit a greater similarity than was thought previously to be the case. Pex20p of Yarrowia lipolytica, Pex18p and Pex21p of Saccharomyces cerevisiae and mammalian Pex5pL fulfil a common function in the PTS2 pathway of their respective organisms. These non-orthologous proteins possess a conserved sequence region that most likely represents a common PTS2-receptor binding site and di-aromatic pentapeptide motifs that could be involved in binding of the putative docking proteins. We propose that not necessarily the same proteins but functional modules of them are conserved in the early steps of peroxisomal protein import. (+info)Yarrowia lipolytica cells mutant for the peroxisomal peroxin Pex19p contain structures resembling wild-type peroxisomes. (3/172)
PEX genes encode peroxins, which are proteins required for peroxisome assembly. The PEX19 gene of the yeast Yarrowia lipolytica was isolated by functional complementation of the oleic acid-nonutilizing strain pex19-1 and encodes Pex19p, a protein of 324 amino acids (34,822 Da). Subcellular fractionation and immunofluorescence microscopy showed Pex19p to be localized primarily to peroxisomes. Pex19p is detected in cells grown in glucose-containing medium, and its levels are not increased by incubation of cells in oleic acid-containing medium, the metabolism of which requires intact peroxisomes. pex19 cells preferentially mislocalize peroxisomal matrix proteins and the peripheral intraperoxisomal membrane peroxin Pex16p to the cytosol, although small amounts of these proteins could be reproducibly localized to a subcellular fraction enriched for peroxisomes. In contrast, the peroxisomal integral membrane protein Pex2p exhibits greatly reduced levels in pex19 cells compared with its levels in wild-type cells. Importantly, pex19 cells were shown by electron microscopy to contain structures that resemble wild-type peroxisomes in regards to size, shape, number, and electron density. Subcellular fractionation and isopycnic density gradient centrifugation confirmed the presence of vesicular structures in pex19 mutant strains that were similar in density to wild-type peroxisomes and that contained profiles of peroxisomal matrix and membrane proteins that are similar to, yet distinct from, those of wild-type peroxisomes. Because peroxisomal structures form in pex19 cells, Pex19p apparently does not function as a peroxisomal membrane protein receptor in Y. lipolytica. Our results are consistent with a role for Y. lipolytica Pex19p in stabilizing the peroxisomal membrane. (+info)External alternative NADH:ubiquinone oxidoreductase redirected to the internal face of the mitochondrial inner membrane rescues complex I deficiency in Yarrowia lipolytica. (4/172)
Alternative NADH:ubiquinone oxidoreductases are single subunit enzymes capable of transferring electrons from NADH to ubiquinone without contributing to the proton gradient across the respiratory membrane. The obligately aerobic yeast Yarrowia lipolytica has only one such enzyme, encoded by the NDH2 gene and located on the external face of the mitochondrial inner membrane. In sharp contrast to ndh2 deletions, deficiencies in nuclear genes for central subunits of proton pumping NADH:ubiquinone oxidoreductases (complex I) are lethal. We have redirected NDH2 to the internal face of the mitochondrial inner membrane by N-terminally attaching the mitochondrial targeting sequence of NUAM, the largest subunit of complex I. Lethality of complex I mutations was rescued by the internal, but not the external version of alternative NADH:ubiquinone oxidoreductase. Internal NDH2 also permitted growth in the presence of complex I inhibitors such as 2-decyl-4-quinazolinyl amine (DQA). Functional expression of NDH2 on both sides of the mitochondrial inner membrane indicates that alternative NADH:ubiquinone oxidoreductase requires no additional components for catalytic activity. Our findings also demonstrate that shuttle mechanisms for the transfer of redox equivalents from the matrix to the cytosolic side of the mitochondrial inner membrane are insufficient in Y. lipolytica. (+info)Role of beta-oxidation enzymes in gamma-decalactone production by the yeast Yarrowia lipolytica. (5/172)
Some microorganisms can transform methyl ricinoleate into gamma-decalactone, a valuable aroma compound, but yields of the bioconversion are low due to (i) incomplete conversion of ricinoleate (C(18)) to the C(10) precursor of gamma-decalactone, (ii) accumulation of other lactones (3-hydroxy-gamma-decalactone and 2- and 3-decen-4-olide), and (iii) gamma-decalactone reconsumption. We evaluated acyl coenzyme A (acyl-CoA) oxidase activity (encoded by the POX1 through POX5 genes) in Yarrowia lipolytica in lactone accumulation and gamma-decalactone reconsumption in POX mutants. Mutants with no acyl-CoA oxidase activity could not reconsume gamma-decalactone, and mutants with a disruption of pox3, which encodes the short-chain acyl-CoA oxidase, reconsumed it more slowly. 3-Hydroxy-gamma-decalactone accumulation during transformation of methyl ricinoleate suggests that, in wild-type strains, beta-oxidation is controlled by 3-hydroxyacyl-CoA dehydrogenase. In mutants with low acyl-CoA oxidase activity, however, the acyl-CoA oxidase controls the beta-oxidation flux. We also identified mutant strains that produced 26 times more gamma-decalactone than the wild-type parents. (+info)Secretion of active anti-Ras single-chain Fv antibody by the yeasts Yarrowia lipolytica and Kluyveromyces lactis. (6/172)
Yarrowia lipolytica and Kluyveromyces lactis secretion vectors were constructed and assessed for the expression of heterologous proteins. An anti-Ras single-chain antibody fragment (scFv) coding sequence was fused in-frame to different pre- or prepro-regions, or downstream from a reporter secretory gene (Arxula adeninivorans glucoamylase), separated by a Kex2 protease (Kex2p)-like processing sequence. Both organisms are able to secrete soluble scFv, with yields depending on the nature of the expression cassette, up to levels ranging from 10 to 20 mg l(-1). N-terminal sequence analysis of the purified scFv showed that fusions are correctly processed to the mature scFv by a signal peptidase or a Kex2p-type endoprotease present in Y. lipolytica and K. lactis. The scFv protein also retains the capacity to bind to a glutathioneS-transferase (GST)-Harvey-Ras(Val12) fusion, indicating that the antibody is functional. These results indicate that the yeasts Y. lipolytica and K. lactis have potential for industrial production of soluble and active scFv. (+info)Acyl-CoA oxidase is imported as a heteropentameric, cofactor-containing complex into peroxisomes of Yarrowia lipolytica. (7/172)
Five isoforms of acyl-CoA oxidase (Aox), designated Aox1p to Aox5p, constitute a 443-kD heteropentameric complex containing one polypeptide chain of each isoform within the peroxisomal matrix of the yeast Yarrowia lipolytica. Assembly of the Aox complex occurs in the cytosol and precedes its import into peroxisomes. Peroxisomal targeting of the Aox complex is abolished in a mutant lacking the peroxin Pex5p, a component of the matrix protein targeting machinery. Import of the Aox complex into peroxisomes does not involve the cytosolic chaperone Pex20p, which mediates the oligomerization and import of peroxisomal thiolase. Aox2p and Aox3p play a pivotal role in the formation of the Aox complex in the cytosol and can substitute for one another in promoting assembly of the complex. In vitro, these subunits retard disassembly of the Aox complex and increase the efficiency of its reassembly. Neither Aox2p nor Aox3p is required for acquisition of the cofactor FAD by other components of the complex. We provide evidence that the Aox2p- and Aox3p-assisted assembly of the Aox complex in the cytosol is mandatory for its import into peroxisomes and that no component of the complex can penetrate the peroxisomal matrix as a monomer. (+info)Genetic control of extracellular protease synthesis in the yeast Yarrowia lipolytica. (8/172)
Depending on the pH of the growth medium, the yeast Yarrowia lipolytica secretes an acidic protease or an alkaline protease, the synthesis of which is also controlled by carbon, nitrogen, and sulfur availability, as well as by the presence of extracellular proteins. Previous results have indicated that the alkaline protease response to pH was dependent on YlRim101p, YlRim8p/YlPalF, and YlRim21p/YlPalH, three components of a conserved pH signaling pathway initially described in Aspergillus nidulans. To identify other partners of this response pathway, as well as pH-independent regulators of proteases, we searched for mutants that affect the expression of either or both acidic and alkaline proteases, using a YlmTn1-transposed genomic library. Four mutations affected only alkaline protease expression and identified the homolog of Saccharomyces cerevisiae SIN3. Eighty-nine mutations affected the expression of both proteases and identified 10 genes. Five of them define a conserved Rim pathway, which acts, as in other ascomycetes, by activating alkaline genes and repressing acidic genes at alkaline pH. Our results further suggest that in Y. lipolytica this pathway is active at acidic pH and is required for the expression of the acidic AXP1 gene. The five other genes are homologous to S. cerevisiae OPT1, SSY5, VPS28, NUP85, and MED4. YlOPT1 and YlSSY5 are not involved in pH sensing but define at least a second protease regulatory pathway. (+info)Yarrowia is a genus of fungi that belongs to the family of Dipodascaceae. It is a type of yeast that is often found in various environments, including plants, soil, and water. One species, Yarrowia lipolytica, has gained attention in biotechnology applications due to its ability to break down fats and oils, produce organic acids, and express heterologous proteins. It's also known to be an opportunistic pathogen in humans, causing rare but serious infections in individuals with weakened immune systems.
Saccharomycetales is an order of fungi that are commonly known as "true yeasts." They are characterized by their single-celled growth and ability to reproduce through budding or fission. These organisms are widely distributed in nature and can be found in a variety of environments, including soil, water, and on the surfaces of plants and animals.
Many species of Saccharomycetales are used in industrial processes, such as the production of bread, beer, and wine. They are also used in biotechnology to produce various enzymes, vaccines, and other products. Some species of Saccharomycetales can cause diseases in humans and animals, particularly in individuals with weakened immune systems. These infections, known as candidiasis or thrush, can affect various parts of the body, including the skin, mouth, and genital area.
Fungal proteins are a type of protein that is specifically produced and present in fungi, which are a group of eukaryotic organisms that include microorganisms such as yeasts and molds. These proteins play various roles in the growth, development, and survival of fungi. They can be involved in the structure and function of fungal cells, metabolism, pathogenesis, and other cellular processes. Some fungal proteins can also have important implications for human health, both in terms of their potential use as therapeutic targets and as allergens or toxins that can cause disease.
Fungal proteins can be classified into different categories based on their functions, such as enzymes, structural proteins, signaling proteins, and toxins. Enzymes are proteins that catalyze chemical reactions in fungal cells, while structural proteins provide support and protection for the cell. Signaling proteins are involved in communication between cells and regulation of various cellular processes, and toxins are proteins that can cause harm to other organisms, including humans.
Understanding the structure and function of fungal proteins is important for developing new treatments for fungal infections, as well as for understanding the basic biology of fungi. Research on fungal proteins has led to the development of several antifungal drugs that target specific fungal enzymes or other proteins, providing effective treatment options for a range of fungal diseases. Additionally, further study of fungal proteins may reveal new targets for drug development and help improve our ability to diagnose and treat fungal infections.
Electron Transport Complex I, also known as NADH:ubiquinone oxidoreductase, is a large protein complex located in the inner mitochondrial membrane of eukaryotic cells and the cytoplasmic membrane of prokaryotic cells. It is the first complex in the electron transport chain, a series of protein complexes that transfer electrons from NADH to oxygen, driving the synthesis of ATP through chemiosmosis.
Complex I consists of multiple subunits, including a flavin mononucleotide (FMN) cofactor and several iron-sulfur clusters, which facilitate the oxidation of NADH and the reduction of ubiquinone (coenzyme Q). The energy released during this electron transfer process is used to pump protons across the membrane, creating a proton gradient that drives ATP synthesis.
Defects in Complex I can lead to various mitochondrial diseases, including neurological disorders and muscle weakness.
Yeasts are single-celled microorganisms that belong to the fungus kingdom. They are characterized by their ability to reproduce asexually through budding or fission, and they obtain nutrients by fermenting sugars and other organic compounds. Some species of yeast can cause infections in humans, known as candidiasis or "yeast infections." These infections can occur in various parts of the body, including the skin, mouth, genitals, and internal organs. Common symptoms of a yeast infection may include itching, redness, irritation, and discharge. Yeast infections are typically treated with antifungal medications.
Peroxisomes are membrane-bound subcellular organelles found in the cytoplasm of eukaryotic cells. They play a crucial role in various cellular processes, including the breakdown of fatty acids and the detoxification of harmful substances such as hydrogen peroxide (H2O2). Peroxisomes contain numerous enzymes, including catalase, which converts H2O2 into water and oxygen, thus preventing oxidative damage to cellular components. They also participate in the biosynthesis of ether phospholipids, a type of lipid essential for the structure and function of cell membranes. Additionally, peroxisomes are involved in the metabolism of reactive oxygen species (ROS) and contribute to the regulation of intracellular redox homeostasis. Dysfunction or impairment of peroxisome function has been linked to several diseases, including neurological disorders, developmental abnormalities, and metabolic conditions.
Alkanes are a group of saturated hydrocarbons, which are characterized by the presence of single bonds between carbon atoms in their molecular structure. The general formula for alkanes is CnH2n+2, where n represents the number of carbon atoms in the molecule.
The simplest and shortest alkane is methane (CH4), which contains one carbon atom and four hydrogen atoms. As the number of carbon atoms increases, the length and complexity of the alkane chain also increase. For example, ethane (C2H6) contains two carbon atoms and six hydrogen atoms, while propane (C3H8) contains three carbon atoms and eight hydrogen atoms.
Alkanes are important components of fossil fuels such as natural gas, crude oil, and coal. They are also used as starting materials in the production of various chemicals and materials, including plastics, fertilizers, and pharmaceuticals. In the medical field, alkanes may be used as anesthetics or as solvents for various medical applications.
Fungal genes refer to the genetic material present in fungi, which are eukaryotic organisms that include microorganisms such as yeasts and molds, as well as larger organisms like mushrooms. The genetic material of fungi is composed of DNA, just like in other eukaryotes, and is organized into chromosomes located in the nucleus of the cell.
Fungal genes are segments of DNA that contain the information necessary to produce proteins and RNA molecules required for various cellular functions. These genes are transcribed into messenger RNA (mRNA) molecules, which are then translated into proteins by ribosomes in the cytoplasm.
Fungal genomes have been sequenced for many species, revealing a diverse range of genes that encode proteins involved in various cellular processes such as metabolism, signaling, and regulation. Comparative genomic analyses have also provided insights into the evolutionary relationships among different fungal lineages and have helped to identify unique genetic features that distinguish fungi from other eukaryotes.
Understanding fungal genes and their functions is essential for advancing our knowledge of fungal biology, as well as for developing new strategies to control fungal pathogens that can cause diseases in humans, animals, and plants.
Batch cell culture techniques refer to a method of growing cells in which all the necessary nutrients are added to the culture medium at the beginning of the growth period. The cells are allowed to grow and multiply until they exhaust the available nutrients, after which the culture is discarded. This technique is relatively simple and inexpensive but lacks the ability to continuously produce cells over an extended period.
In batch cell culture, cells are grown in a closed system with a fixed volume of medium, and no additional nutrients or fresh medium are added during the growth phase. The cells consume the available nutrients as they grow, leading to a decrease in pH, accumulation of waste products, and depletion of essential factors required for cell growth. As a result, the cells eventually stop growing and enter a stationary phase, after which they begin to die due to lack of nutrients and buildup of toxic metabolites.
Batch cell culture techniques are commonly used in research settings where large quantities of cells are needed for experiments or analysis. However, this method is not suitable for the production of therapeutic proteins or other biologics that require continuous cell growth and protein production over an extended period. For these applications, more complex culture methods such as fed-batch or perfusion culture techniques are used.
Fungal DNA refers to the genetic material present in fungi, which are a group of eukaryotic organisms that include microorganisms such as yeasts and molds, as well as larger organisms like mushrooms. The DNA of fungi, like that of all living organisms, is made up of nucleotides that are arranged in a double helix structure.
Fungal DNA contains the genetic information necessary for the growth, development, and reproduction of fungi. This includes the instructions for making proteins, which are essential for the structure and function of cells, as well as other important molecules such as enzymes and nucleic acids.
Studying fungal DNA can provide valuable insights into the biology and evolution of fungi, as well as their potential uses in medicine, agriculture, and industry. For example, researchers have used genetic engineering techniques to modify the DNA of fungi to produce drugs, biofuels, and other useful products. Additionally, understanding the genetic makeup of pathogenic fungi can help scientists develop new strategies for preventing and treating fungal infections.
Oleic acid is a monounsaturated fatty acid that is commonly found in various natural oils such as olive oil, sunflower oil, and peanut oil. Its chemical formula is cis-9-octadecenoic acid, and it is a colorless liquid at room temperature with a slight odor. Oleic acid is an important component of human diet and has been shown to have various health benefits, including reducing the risk of heart disease and improving immune function. It is also used in the manufacture of soaps, cosmetics, and other industrial products.
Molecular sequence data refers to the specific arrangement of molecules, most commonly nucleotides in DNA or RNA, or amino acids in proteins, that make up a biological macromolecule. This data is generated through laboratory techniques such as sequencing, and provides information about the exact order of the constituent molecules. This data is crucial in various fields of biology, including genetics, evolution, and molecular biology, allowing for comparisons between different organisms, identification of genetic variations, and studies of gene function and regulation.
Industrial microbiology is not strictly a medical definition, but it is a branch of microbiology that deals with the use of microorganisms for the production of various industrial and commercial products. In a broader sense, it can include the study of microorganisms that are involved in diseases of animals, humans, and plants, as well as those that are beneficial in industrial processes.
In the context of medical microbiology, industrial microbiology may involve the use of microorganisms to produce drugs, vaccines, or other therapeutic agents. For example, certain bacteria and yeasts are used to ferment sugars and produce antibiotics, while other microorganisms are used to create vaccines through a process called attenuation.
Industrial microbiology may also involve the study of microorganisms that can cause contamination in medical settings, such as hospitals or pharmaceutical manufacturing facilities. These microorganisms can cause infections and pose a risk to patients or workers, so it is important to understand their behavior and develop strategies for controlling their growth and spread.
Overall, industrial microbiology plays an important role in the development of new medical technologies and therapies, as well as in ensuring the safety and quality of medical products and environments.
Yarrowia
Gene density
Yeast
2-methylcitrate dehydratase
Candida oleophila
Cell engineering
Respiratory complex I
Synthesis of nanoparticles by fungi
NADH:ubiquinone reductase (non-electrogenic)
Hydrocarbonoclastic bacteria
Homogentisic acid
2-methylisocitrate dehydratase
Gas to liquids
BZIP intron RNA motif
Isocitric acid
NDUFS7
Eicosapentaenoic acid
Yeast expression platform
Bernard Dujon
Candida blankii
Candida keroseneae
Kluyveromyces lactis
Ogataea polymorpha
Petroleum Remediation Product
Dipodascaceae
Alternative yeast nuclear code
Fuel polishing
List of MeSH codes (B05)
Long-chain-alcohol oxidase
Mycoremediation
Yarrowia - Wikipedia
Yarrowia lipolytica (Wickerham et al.) van der Walt et von Arx - 42281 | ATCC
YALI0 B22968g gene cDNA ORF clone, Yarrowia lipolytica CLIB122 - GenScript
Browse Yarrowia lipolytica CLIB122 ORF cDNA clones by KEGG database, RNA polymerase I, eukaryotes
Optimization of Process Parameters for the Production of Lipase in Submerged Fermentation by Yarrowia lipolytica NCIM 3589
Draft Genome Assemblies of Ionic Liquid-Resistant Yarrowia lipolytica PO1f and Its Superior Evolved Strain, YlCW001 - DOE Joint...
Recombinant β-Carotene Production by Yarrowia lipolytica - Assessing the Potential of Micro-Scale Fermentation Analysis in Cell...
Genomic analysis of novel Yarrowia-like yeast symbionts associated with the carrion-feeding burying beetle Nicrophorus...
ATP-dependent 6-phosphofructokinase (Yarrowia lipolytica CLIB122) | Protein Target - PubChem
Expression of an endoglucanase-cellobiohydrolase fusion protein in Saccharomyces cerevisiae, Yarrowia lipolytica, and Lipomyces...
Technology - Yarrowia Canifelox
Info - Yarrowia lipolytica CLIB89(W29)
YARROWIA EQUINOX Sport 1,5 kg
Yarrowia lipolytica yeast biomass | Tomorrow's Food and Feed
README.md · master · gryc-data / yarrowia lipolytica-a101 · GitLab
Investigating the Influence of Glycerol on the Utilization of Glucose in Yarrowia lipolytica Using RNA-Seq-Based Transcriptomics
Anamorph and Teleomorph Names for Candida Species | Fungal Diseases | CDC
Repositório UFT: Otimização da produção de celulases por Yarrowia divulgata isolada de coco tucum
Microbial synthesis of natural products originating from medicinal plants and fungi
Biovalorisation of crude glycerol and xylose into xylitol by oleaginous yeast Yarrowia lipolytica<...
Wpływ warunków hodowli drożdży Yarrowia lipolytica na wydajność syntezy erytrytolu z glicerolu - Lower Silesian Digital Library
Plants | Free Full-Text | The Suitability of Orthogonal Hosts to Study Plant Cell Wall Biosynthesis
Surveying the lipogenesis landscape in Yarrowia lipolytica through understanding the function of a Mga2p regulatory protein...
In silico and in vivo analysis of signal peptides effect on recombinant glucose oxidase production in nonconventional yeast...
Metabolic engineering of the oleaginous yeast Yarrowia lipolytica PO1f for production of erythritol from glycerol |...
Design of an efficient medium for heterologous protein production in Yarrowia lipolytica: case of human interferon alpha 2b. -...
A modular pathway engineering strategy for the high-level production of β-ionone in Yarrowia lipolytica | Microbial Cell...
Crystal Structures of Cyclohexanone Monooxygenase Reveal Complex Domain Movements and a Sliding Cofactor | Journal of the...
SciELO - Brazil - The isolation of pentose-assimilating yeasts and their xylose fermentation potential The isolation of...
Addgene: pUC-LeumLipolytica yeast biomass3
- Administrative adjustments are made to update the Annex in Regulation (EU) No. 2017/2470 establishing the Union list of novel foods in accordance with Regulation (EU) No. 2015/2283 on novel foods , to include reference for the authorisation of Yarrowia lipolytica yeast biomass * to be placed on the market as a novel food. (thecompliancepeople.co.uk)
- This sets out the recommended maximum levels on how much Yarrowia lipolytica yeast biomass can be consumed per day. (thecompliancepeople.co.uk)
- Yarrowia lipolytica yeast biomass is mostly composed of proteins and fibre. (thecompliancepeople.co.uk)
Yeast Yarrowia lipolytica5
- In this study, we demonstrated that metabolic engineering can be used to improve the production of erythritol from glycerol in the yeast Yarrowia lipolytica . (researcher-app.com)
- 5. Engineering of unconventional yeast Yarrowia lipolytica for efficient succinic acid production from glycerol at low pH. (nih.gov)
- 11. [Biosynthesis of isocitric acid by the yeast yarrowia lipolytica and its regulation]. (nih.gov)
- 17. Physiologo-biochemical characteristics of citrate-producing yeast Yarrowia lipolytica grown on glycerol-containing waste of biodiesel industry. (nih.gov)
- 18. Both decrease in ACL1 gene expression and increase in ICL1 gene expression in marine-derived yeast Yarrowia lipolytica expressing INU1 gene enhance citric acid production from inulin. (nih.gov)
Dipodascaceae1
- Yarrowia is a fungal genus in the family Dipodascaceae. (wikipedia.org)
Citric acid production4
- 4. Investigation of mitochondrial protein expression profiles of Yarrowia lipolytica in response to citric acid production. (nih.gov)
- 7. D-stat culture for studying the metabolic shifts from oxidative metabolism to lipid accumulation and citric acid production in Yarrowia lipolytica. (nih.gov)
- 9. Oxygen requirements for growth and citric acid production of Yarrowia lipolytica. (nih.gov)
- 14. Substrates and oxygen dependent citric acid production by Yarrowia lipolytica: insights through transcriptome and fluxome analyses. (nih.gov)
Nicaud JM1
- Chapter 82 - Yarrowia van der Walt & von Arx (1980)", The Yeasts (Fifth Edition), London: Elsevier, pp. 927-929, ISBN 978-0-444-52149-1, retrieved 2020-06-24 Nicaud JM (October 2012). (wikipedia.org)
Hansenii3
- from cheese and saline solution and were identified as Yarrowia lipolytica and Debaryomyces hansenii using MALDI-TOF. (pulsus.com)
- Four batches of cheeses were produced, in which the control cheese involved only commercial starter culture while YL, DH and KL cheeses were produced with the incorporation of individual Yarrowia lipolytica, Debaryomyces hansenii and Kluyveromyces lactis, respectively. (bvsalud.org)
- Debaryomyces hansenii 97 (D. hansenii 97) and Yarrowia lipolytica 242 (Y. lipolytica 242) are yeasts that protect wildtype zebrafish (Danio rerio) larvae against a Vibrio anguillarum (V. anguillarum) infection, increasing their survival rate. (bvsalud.org)
Kluyveromyces1
- Yarrowia lipolytica and Kluyveromyces lactis occur as part of Stilton cheese microflora yet are not controlled during production. (birmingham.ac.uk)
Strains1
- Yarrowia lipolytica is a potentially valuable species for terpenoid production, and NHEJ-mediated modular integration is effective for expression library construction and screening of high-producer strains. (springer.com)
Mitochondrial3
- 1. The mitochondrial citrate carrier in Yarrowia lipolytica: Its identification, characterization and functional significance for the production of citric acid. (nih.gov)
- 2. Engineering Yarrowia lipolytica for the selective and high-level production of isocitric acid through manipulation of mitochondrial dicarboxylate-tricarboxylate carriers. (nih.gov)
- 15. Genetic inactivation of the Carnitine/Acetyl-Carnitine mitochondrial carrier of Yarrowia lipolytica leads to enhanced odd-chain fatty acid production. (nih.gov)
Strain1
- Citric acid (CA) productivity by Yarrowia lipolytica dependents on strain type, carbon source, carbon to nitrogen (C/N) molar ratio as well as physicochemical conditions (pH, temperature, oxygen transfer rate, etc. (ucp.pt)
Species2
- For a while the genus was monotypic, containing the single species Yarrowia lipolytica, a yeast that can use unusual carbon sources, such as hydrocarbons. (wikipedia.org)
- Other potential MDR Candida species are Candida krusei , Candida lusitaniae , Candida kefyr , Yarrowia ( Candida ) lypolitica, and Candida rugosa. (medscape.com)
Glycerol1
- 16. Modulation of the Glycerol Phosphate availability led to concomitant reduction in the citric acid excretion and increase in lipid content and yield in Yarrowia lipolytica. (nih.gov)
Production3
- Yarrowia lipolytica , a non-traditional oil yeast, has been widely used as a platform for lipid production. (springer.com)
- Yarrowia lipolytica is a biotechnological chassis for the production of a range of products, such as microbial oils and organic acids. (nidatranslate.com)
- Par conséquent, des systèmes de production compétitifs ont été développés afin de subvenir à la haute demande en molécules aromatiques naturelles. (ac.be)
Growth3
- Yarrowia lipolytica has dimorphic growth, which means it can grow in two different phenotypes. (wikipedia.org)
- The objective was to evaluate the efficacy of increasing supplementation of Yarrowia lipolytica (YL) up to 3.0% replacing 1.6% poultry fat and 0.9% blood plasma for growth performance, intestinal health and nutrient digestibility of diets fed to nursery pigs. (animbiosci.org)
- Yarrowia lipolytica can be supplemented at 1.5% in nursery diets, replacing 0.8% poultry fat and 0.45% blood plasma without affecting growth performance, intestinal health and nutrient digestibility. (animbiosci.org)
Current1
- The development of Lipomod® 833L2 also saw Biocatalysts Ltd adding a new yeast host, Yarrowia lipolytica , to its current range of expression hosts. (biocatalysts.com)
Introduction1
- The introduction of Yarrowia lipolytica meant Biocatalysts Ltd could achieve higher fermentation yields and activity of their new product, Lipomod® 833L2. (biocatalysts.com)
