Restoration of integrity to traumatized tissue.
Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity.
Invasion of the site of trauma by pathogenic microorganisms.
Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
Wounds caused by objects penetrating the skin.
Injuries incurred during participation in competitive or non-competitive sports.
Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
Adverse functional, metabolic, or structural changes in ischemic tissues resulting from the restoration of blood flow to the tissue (REPERFUSION), including swelling; HEMORRHAGE; NECROSIS; and damage from FREE RADICALS. The most common instance is MYOCARDIAL REPERFUSION INJURY.
Infection occurring at the site of a surgical incision.
An anatomic severity scale based on the Abbreviated Injury Scale (AIS) and developed specifically to score multiple traumatic injuries. It has been used as a predictor of mortality.
Damage to any compartment of the lung caused by physical, chemical, or biological agents which characteristically elicit inflammatory reaction. These inflammatory reactions can either be acute and dominated by NEUTROPHILS, or chronic and dominated by LYMPHOCYTES and MACROPHAGES.
General or unspecified injuries involving the leg.
Damage or trauma inflicted to the eye by external means. The concept includes both surface injuries and intraocular injuries.
Penetrating wounds caused by a pointed object.
General or unspecified injuries to the neck. It includes injuries to the skin, muscles, and other soft tissues of the neck.
General or unspecified injuries involving organs in the abdominal cavity.
A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).
General or unspecified injuries to the chest area.
Injuries resulting when a person is struck by particles impelled with violent force from an explosion. Blast causes pulmonary concussion and hemorrhage, laceration of other thoracic and abdominal viscera, ruptured ear drums, and minor effects in the central nervous system. (From Dorland, 27th ed)
Pathologic process consisting of a partial or complete disruption of the layers of a surgical wound.
General or unspecified injuries involving the arm.
General or unspecified injuries to the hand.
Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.
Injuries involving the vertebral column.
Injuries to the knee or the knee joint.
A vascular connective tissue formed on the surface of a healing wound, ulcer, or inflamed tissue. It consists of new capillaries and an infiltrate containing lymphoid cells, macrophages, and plasma cells.
The application of a vacuum across the surface of a wound through a foam dressing cut to fit the wound. This removes wound exudates, reduces build-up of inflammatory mediators, and increases the flow of nutrients to the wound thus promoting healing.
General or unspecified injuries to the heart.
Injuries of tissue other than bone. The concept is usually general and does not customarily refer to internal organs or viscera. It is meaningful with reference to regions or organs where soft tissue (muscle, fat, skin) should be differentiated from bones or bone tissue, as "soft tissue injuries of the hand".
General or unspecified injuries to the soft tissue or bony portions of the face.
Classification system for assessing impact injury severity developed and published by the American Association for Automotive Medicine. It is the system of choice for coding single injuries and is the foundation for methods assessing multiple injuries or for assessing cumulative effects of more than one injury. These include Maximum AIS (MAIS), Injury Severity Score (ISS), and Probability of Death Score (PODS).
The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.
Injuries caused by impact with a blunt object where there is no penetration of the skin.
General or unspecified injuries to the posterior part of the trunk. It includes injuries to the muscles of the back.
Material used for wrapping or binding any part of the body.
Damage to the MYOCARDIUM resulting from MYOCARDIAL REPERFUSION (restoration of blood flow to ischemic areas of the HEART.) Reperfusion takes place when there is spontaneous thrombolysis, THROMBOLYTIC THERAPY, collateral flow from other coronary vascular beds, or reversal of vasospasm.
Traumatic injuries involving the cranium and intracranial structures (i.e., BRAIN; CRANIAL NERVES; MENINGES; and other structures). Injuries may be classified by whether or not the skull is penetrated (i.e., penetrating vs. nonpenetrating) or whether there is an associated hemorrhage.
Traumatic injuries to the cranium where the integrity of the skull is not compromised and no bone fragments or other objects penetrate the skull and dura mater. This frequently results in mechanical injury being transmitted to intracranial structures which may produce traumatic brain injuries, hemorrhage, or cranial nerve injury. (From Rowland, Merritt's Textbook of Neurology, 9th ed, p417)
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
A relatively common sequela of blunt head injury, characterized by a global disruption of axons throughout the brain. Associated clinical features may include NEUROBEHAVIORAL MANIFESTATIONS; PERSISTENT VEGETATIVE STATE; DEMENTIA; and other disorders.
General or unspecified injuries involving the foot.
Injuries sustained from incidents in the course of work-related activities.
A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, and chemicals from the environment.
Damages to the CAROTID ARTERIES caused either by blunt force or penetrating trauma, such as CRANIOCEREBRAL TRAUMA; THORACIC INJURIES; and NECK INJURIES. Damaged carotid arteries can lead to CAROTID ARTERY THROMBOSIS; CAROTID-CAVERNOUS SINUS FISTULA; pseudoaneurysm formation; and INTERNAL CAROTID ARTERY DISSECTION. (From Am J Forensic Med Pathol 1997, 18:251; J Trauma 1994, 37:473)
Injuries to the PERIPHERAL NERVES.
Harm or hurt to the ankle or ankle joint usually inflicted by an external source.
Elements of limited time intervals, contributing to particular results or situations.
Deeply perforating or puncturing type intraocular injuries.
Injuries to blood vessels caused by laceration, contusion, puncture, or crush and other types of injuries. Symptoms vary by site and mode of injuries and may include bleeding, bruising, swelling, pain, and numbness. It does not include injuries secondary to pathologic function or diseases such as ATHEROSCLEROSIS.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
Systems for assessing, classifying, and coding injuries. These systems are used in medical records, surveillance systems, and state and national registries to aid in the collection and reporting of trauma.
General or unspecified injuries involving the fingers.
Accidents on streets, roads, and highways involving drivers, passengers, pedestrians, or vehicles. Traffic accidents refer to AUTOMOBILES (passenger cars, buses, and trucks), BICYCLING, and MOTORCYCLES but not OFF-ROAD MOTOR VEHICLES; RAILROADS nor snowmobiles.
Unforeseen occurrences, especially injuries in the course of work-related activities.
Maintenance of the hygienic state of the skin under optimal conditions of cleanliness and comfort. Effective in skin care are proper washing, bathing, cleansing, and the use of soaps, detergents, oils, etc. In various disease states, therapeutic and protective solutions and ointments are useful. The care of the skin is particularly important in various occupations, in exposure to sunlight, in neonates, and in PRESSURE ULCER.
Material, usually gauze or absorbent cotton, used to cover and protect wounds, to seal them from contact with air or bacteria. (From Dorland, 27th ed)
Penetrating stab wounds caused by needles. They are of special concern to health care workers since such injuries put them at risk for developing infectious disease.
Head injuries which feature compromise of the skull and dura mater. These may result from gunshot wounds (WOUNDS, GUNSHOT), stab wounds (WOUNDS, STAB), and other forms of trauma.
The fibrous tissue that replaces normal tissue during the process of WOUND HEALING.
Hyperextension injury to the neck, often the result of being struck from behind by a fast-moving vehicle, in an automobile accident. (From Segen, The Dictionary of Modern Medicine, 1992)
Pulmonary injury following the breathing in of toxic smoke from burning materials such as plastics, synthetics, building materials, etc. This injury is the most frequent cause of death in burn patients.
Injuries resulting in hemorrhage, usually manifested in the skin.
Injuries caused by electric currents. The concept excludes electric burns (BURNS, ELECTRIC), but includes accidental electrocution and electric shock.
Multiple physical insults or injuries occurring simultaneously.
Disruption of structural continuity of the body as a result of the discharge of firearms.
The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
A partial or complete return to the normal or proper physiologic activity of an organ or part following disease or trauma.
Injuries to the fibrous cords of connective tissue which attach muscles to bones or other structures.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Traumatic or other damage to teeth including fractures (TOOTH FRACTURES) or displacements (TOOTH LUXATION).
Epidermal cells which synthesize keratin and undergo characteristic changes as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
A game in which a round inflated ball is advanced by kicking or propelling with any part of the body except the hands or arms. The object of the game is to place the ball in opposite goals.
The physiological renewal, repair, or replacement of tissue.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
Efforts and designs to reduce the incidence of unexpected undesirable events in various environments and situations.
A collective term for muscle and ligament injuries without dislocation or fracture. A sprain is a joint injury in which some of the fibers of a supporting ligament are ruptured but the continuity of the ligament remains intact. A strain is an overstretching or overexertion of some part of the musculature.
An ulceration caused by prolonged pressure on the SKIN and TISSUES when one stays in one position for a long period of time, such as lying in bed. The bony areas of the body are the most frequently affected sites which become ischemic (ISCHEMIA) under sustained and constant pressure.
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
Conditions characterized by persistent brain damage or dysfunction as sequelae of cranial trauma. This disorder may result from DIFFUSE AXONAL INJURY; INTRACRANIAL HEMORRHAGES; BRAIN EDEMA; and other conditions. Clinical features may include DEMENTIA; focal neurologic deficits; PERSISTENT VEGETATIVE STATE; AKINETIC MUTISM; or COMA.
Lung damage that is caused by the adverse effects of PULMONARY VENTILATOR usage. The high frequency and tidal volumes produced by a mechanical ventilator can cause alveolar disruption and PULMONARY EDEMA.
Injuries to the wrist or the wrist joint.
Materials used in closing a surgical or traumatic wound. (From Dorland, 28th ed)
The transparent anterior portion of the fibrous coat of the eye consisting of five layers: stratified squamous CORNEAL EPITHELIUM; BOWMAN MEMBRANE; CORNEAL STROMA; DESCEMET MEMBRANE; and mesenchymal CORNEAL ENDOTHELIUM. It serves as the first refracting medium of the eye. It is structurally continuous with the SCLERA, avascular, receiving its nourishment by permeation through spaces between the lamellae, and is innervated by the ophthalmic division of the TRIGEMINAL NERVE via the ciliary nerves and those of the surrounding conjunctiva which together form plexuses. (Cline et al., Dictionary of Visual Science, 4th ed)
A competitive team sport played on a rectangular field. This is the American or Canadian version of the game and also includes the form known as rugby. It does not include non-North American football (= SOCCER).
General or unspecified injuries involving the face and jaw (either upper, lower, or both).
Stratified squamous epithelium that covers the outer surface of the CORNEA. It is smooth and contains many free nerve endings.
Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.
Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.
A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
Torn, ragged, mangled wounds.
Reconstitution of eroded or injured EPITHELIUM by proliferation and migration of EPITHELIAL CELLS from below or adjacent to the damaged site.
The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes.
Injuries to the optic nerve induced by a trauma to the face or head. These may occur with closed or penetrating injuries. Relatively minor compression of the superior aspect of orbit may also result in trauma to the optic nerve. Clinical manifestations may include visual loss, PAPILLEDEMA, and an afferent pupillary defect.
Damages to the EMBRYO, MAMMALIAN or the FETUS before BIRTH. Damages can be caused by any factors including biological, chemical, or physical.
Synthetic material used for the treatment of burns and other conditions involving large-scale loss of skin. It often consists of an outer (epidermal) layer of silicone and an inner (dermal) layer of collagen and chondroitin 6-sulfate. The dermal layer elicits new growth and vascular invasion and the outer layer is later removed and replaced by a graft.
A polypeptide substance comprising about one third of the total protein in mammalian organisms. It is the main constituent of SKIN; CONNECTIVE TISSUE; and the organic substance of bones (BONE AND BONES) and teeth (TOOTH).
A syndrome characterized by progressive life-threatening RESPIRATORY INSUFFICIENCY in the absence of known LUNG DISEASES, usually following a systemic insult such as surgery or major TRAUMA.
The development of new BLOOD VESSELS during the restoration of BLOOD CIRCULATION during the healing process.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Renewal or physiological repair of damaged nerve tissue.
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.
Techniques for securing together the edges of a wound, with loops of thread or similar materials (SUTURES).
Harmful effects of non-experimental exposure to ionizing or non-ionizing radiation in VERTEBRATES.
Breaks in bones.
A hemeprotein from leukocytes. Deficiency of this enzyme leads to a hereditary disorder coupled with disseminated moniliasis. It catalyzes the conversion of a donor and peroxide to an oxidized donor and water. EC
Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.
Experimentally produced harmful effects of ionizing or non-ionizing RADIATION in CHORDATA animals.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.
Mechanical or anoxic trauma incurred by the infant during labor or delivery.
The functions of the skin in the human and animal body. It includes the pigmentation of the skin.
Falls due to slipping or tripping which may result in injury.
A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products (Sies, Oxidative Stress, 1991, pxv-xvi).
Specialized hospital facilities which provide diagnostic and therapeutic services for trauma patients.
General or unspecified injuries involving the hip.
The pathological process occurring in cells that are dying from irreparable injuries. It is caused by the progressive, uncontrolled action of degradative ENZYMES, leading to MITOCHONDRIAL SWELLING, nuclear flocculation, and cell lysis. It is distinct it from APOPTOSIS, which is a normal, regulated cellular process.
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
A scale that assesses the response to stimuli in patients with craniocerebral injuries. The parameters are eye opening, motor response, and verbal response.
A snow sport which uses skis to glide over the snow. It does not include water-skiing.
The diffusion or accumulation of neutrophils in tissues or cells in response to a wide variety of substances released at the sites of inflammatory reactions.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
A nonspecific term used to describe transient alterations or loss of consciousness following closed head injuries. The duration of UNCONSCIOUSNESS generally lasts a few seconds, but may persist for several hours. Concussions may be classified as mild, intermediate, and severe. Prolonged periods of unconsciousness (often defined as greater than 6 hours in duration) may be referred to as post-traumatic coma (COMA, POST-HEAD INJURY). (From Rowland, Merritt's Textbook of Neurology, 9th ed, p418)
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
Skin breakdown or ulceration caused by VARICOSE VEINS in which there is too much hydrostatic pressure in the superficial venous system of the leg. Venous hypertension leads to increased pressure in the capillary bed, transudation of fluid and proteins into the interstitial space, altering blood flow and supply of nutrients to the skin and subcutaneous tissues, and eventual ulceration.
Granular leukocytes having a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.
Tongues of skin and subcutaneous tissue, sometimes including muscle, cut away from the underlying parts but often still attached at one end. They retain their own microvasculature which is also transferred to the new site. They are often used in plastic surgery for filling a defect in a neighboring region.
A long, narrow, and flat bone commonly known as BREASTBONE occurring in the midsection of the anterior thoracic segment or chest region, which stabilizes the rib cage and serves as the point of origin for several muscles that move the arms, head, and neck.
Personal devices for protection of heads from impact, penetration from falling and flying objects, and from limited electric shock and burn.
Dressings comprised of a self-adhesive matrix to which hydrophilic absorbent particles are embedded. The particles consist of CELLULOSE derivatives; calcium ALGINATES; PECTINS; or GELS. The utility is based on providing a moist environment for WOUND HEALING.
All of the processes involved in increasing CELL NUMBER including CELL DIVISION.
Non-human animals, selected because of specific characteristics, for use in experimental research, teaching, or testing.
A layer of vascularized connective tissue underneath the EPIDERMIS. The surface of the dermis contains innervated papillae. Embedded in or beneath the dermis are SWEAT GLANDS; HAIR FOLLICLES; and SEBACEOUS GLANDS.
Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.
Equipment required for engaging in a sport (such as balls, bats, rackets, skis, skates, ropes, weights) and devices for the protection of athletes during their performance (such as masks, gloves, mouth pieces).
The external, nonvascular layer of the skin. It is made up, from within outward, of five layers of EPITHELIUM: (1) basal layer (stratum basale epidermidis); (2) spinous layer (stratum spinosum epidermidis); (3) granular layer (stratum granulosum epidermidis); (4) clear layer (stratum lucidum epidermidis); and (5) horny layer (stratum corneum epidermidis).
Severe or complete loss of motor function in all four limbs which may result from BRAIN DISEASES; SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; or rarely MUSCULAR DISEASES. The locked-in syndrome is characterized by quadriplegia in combination with cranial muscle paralysis. Consciousness is spared and the only retained voluntary motor activity may be limited eye movements. This condition is usually caused by a lesion in the upper BRAIN STEM which injures the descending cortico-spinal and cortico-bulbar tracts.
Human or animal tissue used as temporary wound coverings.
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Traumatic injuries to the brain, cranial nerves, spinal cord, autonomic nervous system, or neuromuscular system, including iatrogenic injuries induced by surgical procedures.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.
Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions.
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
Severe or complete loss of motor function in the lower extremities and lower portions of the trunk. This condition is most often associated with SPINAL CORD DISEASES, although BRAIN DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; and MUSCULAR DISEASES may also cause bilateral leg weakness.
Exudates are fluids, CELLS, or other cellular substances that are slowly discharged from BLOOD VESSELS usually from inflamed tissues. Transudates are fluids that pass through a membrane or squeeze through tissue or into the EXTRACELLULAR SPACE of TISSUES. Transudates are thin and watery and contain few cells or PROTEINS.
Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
Dysfunction of one or more cranial nerves causally related to a traumatic injury. Penetrating and nonpenetrating CRANIOCEREBRAL TRAUMA; NECK INJURIES; and trauma to the facial region are conditions associated with cranial nerve injuries.
Injuries to the part of the upper limb of the body between the wrist and elbow.
The therapeutic intermittent administration of oxygen in a chamber at greater than sea-level atmospheric pressures (three atmospheres). It is considered effective treatment for air and gas embolisms, smoke inhalation, acute carbon monoxide poisoning, caisson disease, clostridial gangrene, etc. (From Segen, Dictionary of Modern Medicine, 1992). The list of treatment modalities includes stroke.
Hospital department responsible for the administration and provision of immediate medical or surgical care to the emergency patient.
The first seven VERTEBRAE of the SPINAL COLUMN, which correspond to the VERTEBRAE of the NECK.
The grafting of skin in humans or animals from one site to another to replace a lost portion of the body surface skin.
A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
The MUSCLES, bones (BONE AND BONES), and CARTILAGE of the body.
An enzyme that catalyzes the conversion of L-alanine and 2-oxoglutarate to pyruvate and L-glutamate. (From Enzyme Nomenclature, 1992) EC
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Antibacterial used topically in burn therapy.
The washing of a body cavity or surface by flowing water or solution for therapy or diagnosis.
Making an incision in the STERNUM.
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.)
Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.
Forcible or traumatic tear or break of an organ or other soft part of the body.
One or more layers of EPITHELIAL CELLS, supported by the basal lamina, which covers the inner or outer surfaces of the body.
A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.
A tetrameric enzyme that, along with the coenzyme NAD+, catalyzes the interconversion of LACTATE and PYRUVATE. In vertebrates, genes for three different subunits (LDH-A, LDH-B and LDH-C) exist.
A space in which the pressure is far below atmospheric pressure so that the remaining gases do not affect processes being carried on in the space.
Traumatic injuries to the facial nerve. This may result in FACIAL PARALYSIS, decreased lacrimation and salivation, and loss of taste sensation in the anterior tongue. The nerve may regenerate and reform its original pattern of innervation, or regenerate aberrantly, resulting in inappropriate lacrimation in response to gustatory stimuli (e.g., "crocodile tears") and other syndromes.
Traumatic injuries to the HYPOGLOSSAL NERVE.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Devices designed to provide personal protection against injury to individuals exposed to hazards in industry, sports, aviation, or daily activities.
The relationship between the dose of an administered drug and the response of the organism to the drug.
Pathological processes of the LIVER.
Two-wheeled, engine-driven vehicles.
The process by which chemical compounds provide protection to cells against harmful agents.
A sweet viscous liquid food, produced in the honey sacs of various bees from nectar collected from flowers. The nectar is ripened into honey by inversion of its sucrose sugar into fructose and glucose. It is somewhat acidic and has mild antiseptic properties, being sometimes used in the treatment of burns and lacerations.
Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.
A cylindrical column of tissue that lies within the vertebral canal. It is composed of WHITE MATTER and GRAY MATTER.
Any adverse condition in a patient occurring as the result of treatment by a physician, surgeon, or other health professional, especially infections acquired by a patient during the course of treatment.
Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.
Burns of the respiratory tract caused by heat or inhaled chemicals.
Biological activities and functions of the SKIN.
The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.

Non-fatal injuries sustained by seatbelt wearers: a comparative study. (1/5118)

The injuries sustained by 969 drivers and front-seat passengers in road-traffic accidents were studied. Altogether 196 (20-2%) of the drivers and passengers were wearing seat belts and 773 (79-8%) were not. The injuries among the two groups differed greatly in both severity and distribution. A total of 54 (27-6%) of the seatbelt wearers sustained one or more fractures compared with 300 (38-8%) of the non-wearers, and 18 (9-2%) of the seatbelt wearers were severely injured compared with 300 (38-8%) of the non-wearers. Soft-tissue injuries to the face were sustained by only 29 (14-8%) of the seatbelt wearers compared with 425 (55%) of the non-wearers. Since wearing seatbelts may become compulsory, the type and pattern of injuries to be expected in wearers should be appreciated.  (+info)

HLA-DR expression and soluble HLA-DR levels in septic patients after trauma. (2/5118)

OBJECTIVE: To determine if cellular and soluble HLA-DR molecules may be relevant in severely injured patients for the development of gram-positive or gram-negative sepsis. SUMMARY BACKGROUND DATA: HLA-DR molecules play a central role in the specific immune response to infection. The reduced HLA-DR expression on monocytes is considered to correlate with infectious complications and the development of sepsis. Data on the role of HLA-DR expression on T cells and soluble HLA-DR molecules are rare. METHODS: HLA-DR expression on monocytes and T cells was measured by flow cytometry. Plasma levels of soluble HLA-DR were studied by enzyme-linked immunosorbent assay. RESULTS: HLA-DR expression on circulating T cells, calculated as mean fluorescence intensity in channels, was reduced at day 1 after admission in 20 patients with subsequent severe sepsis compared with 46 patients without sepsis. The septic patients immediately after trauma had significantly lower soluble HLA-DR plasma levels than the nonseptic patients. At day 2 after admission, HLA-DR expression on monocytes was significantly lower in the severe sepsis group than in the patients without sepsis, and lasted until day 14 after injury. CONCLUSIONS: In severely injured patients, decreased levels of cellular and soluble HLA-DR appear as early indicators of an immune deviation associated with the development of severe sepsis. Moreover, immune alterations of different cell types may promote distinct kinds of septicemia.  (+info)

Bioelectrical impedance plethysmographic analysis of body composition in critically injured and healthy subjects. (3/5118)

BACKGROUND: Determination of body composition during critical illness is complex because of various patient-related and technical factors. Bioelectrical impedance is a promising technique for the analysis of body composition; however, its clinical utility in critically injured patients is unknown. OBJECTIVE: The purpose of this study was to compare bioelectrical impedance with metabolic activity in healthy and critically injured patients. If bioelectrical impedance accurately determines body composition during critical illness, the slope between body-composition variables and oxygen consumption would be the same in critically injured and healthy subjects. DESIGN: There is a strong linear relation between body composition and metabolic activity. In the present study, body composition (fat-free mass and body cell mass) was determined by using bioelectrical impedance and resting metabolic activity (metabolic rate and oxygen consumption) by using gas exchange analysis in a group of healthy and critically injured subjects. The relation between these variables was compared by using linear regression to a similar relation established by hydrostatic weighing in a large historical control group. RESULTS: The slope of the line relating fat-free mass to resting metabolic rate was the same in the healthy and critically ill groups (P = 0.62) and each was similar to the slope of the line for the control group. However, in 37% of the critically injured group, overhydration contributed to an increase in fat-free mass, disturbing the relation with resting metabolic rate. The slope of the line relating body cell mass to oxygen consumption in our healthy and critically ill groups was almost identical. CONCLUSION: These results support the use of bioelectrical impedance to determine body cell mass in healthy and critically ill subjects.  (+info)

Ten-year trend in survival and resource utilization at a level I trauma center. (4/5118)

OBJECTIVE: To determine the impact of increasing trauma center experience over time on survival and resource utilization. METHODS: The authors studied a retrospective cohort at a single level I trauma center over a 10-year period, from 1986 to 1995. Patients included all hospital admissions and emergency department deaths. The main outcome measures were the case-fatality rate adjusted for injury severity, hospital length of stay, and costs. RESULTS: A total of 25,979 patients were admitted or died. The number of patients per year increased, from 2063 in 1986 to 3313 in 1995. The proportion of patients transferred from another institution increased from 16.2% to 34.4%. Although mean length of stay declined by 28.4%, from 9.5 to 6.8 days, costs increased by 16.7%, from $14,174 to $16,547. The use of specific radiologic investigations increased; the frequency of operative procedures either remained unchanged (craniotomy, fracture fixation) or decreased (celiotomy). After adjusting for injury severity and demographic factors, the mortality rate decreased over 10 years. The improvement in survival was confined to patients with an injury severity score > or =16. CONCLUSION: Over a 10-year period, the case-fatality rate declined in patients with severe injuries. Overall acute care costs increased, partially because of the increased use of radiologic investigations. Even in otherwise established trauma centers, increasing cumulative experience results in improved survival rates in the most severely injured patients. These data suggest that experience contributes to a decrease in mortality rate after severe trauma and that developing trauma systems should consider this factor and limit the number of designated centers to maximize cumulative experience at individual centers.  (+info)

Dependence of explicit and implicit memory on hypnotic state in trauma patients. (5/5118)

BACKGROUND: It is still unclear whether memory of intraoperative events results entirely from moments of inadequate anesthesia. The current study was designed to determine whether the probability of memory declines with increasing depth of the hypnotic state. METHOD: A list of words was played via headphones during surgery to patients who had suffered acute trauma. Several commonly used indicators of anesthetic effect, including the bispectral index, were recorded during word presentation. First, these indicators served as predictors of the memory performance in a postoperative word stem completion test. Second, general memory performance observed in the first part was separated into explicit and implicit memory using the process dissociation procedure, and then two models of memory were compared: One model assumed that the probability of explicit and implicit memory decreases with increasing depth of hypnotic state (individual differences model), whereas the other assumed equal memory performance for all patients regardless of their level of hypnotic state. RESULTS: General memory performance declined with decreasing bispectral index values. None of the other indicators of hypnotic state were related to general memory performance. Memory was still significant at bispectral index levels between 60 and 40. A comparison of the two models of memory resulted in a better fit of the individual differences model, thus providing evidence of a dependence of explicit and implicit memory on the hypnotic state. Quantification of explicit and implicit memory revealed a significant implicit but no reliable explicit memory performance. CONCLUSIONS: This study clearly indicates that memory is related to the depth of hypnosis. The observed memory performance should be interpreted in terms of implicit memory. Auditory information processing occurred at bispectral index levels between 60 and 40.  (+info)

Early growth response factor-1 induction by injury is triggered by release and paracrine activation by fibroblast growth factor-2. (6/5118)

Cell migration and proliferation that follows injury to the artery wall is preceded by signaling and transcriptional events that converge at the promoters of multiple genes whose products can influence formation of the neointima. Transcription factors, such as early growth response factor-1 (Egr-1), with nucleotide recognition elements in the promoters of many pathophysiologically relevant genes, are expressed at the endothelial wound edge within minutes of injury. The mechanisms underlying the inducible expression of Egr-1 in this setting are not clear. Understanding this process would provide important mechanistic insights into the earliest events in the response to injury. In this report, we demonstrate that fibroblast growth factor-2 (FGF-2) is released by injury and that antibodies to FGF-2 almost completely abrogate the activation and nuclear accumulation of Egr-1. FGF-2-inducible egr-1-promoter-dependent expression is blocked by PD98059, a specific inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK)-1/2 (MEK-1/2), as well as by dominant negative mutants of ERK-1/2. Inducible ERK phosphorylation after injury is dependent on release and stimulation by endogenous FGF-2. Antisense oligonucleotides directed at egr-1 mRNA suggest that Egr-1 plays a necessary role in endothelial repair after denudation of the monolayer. These findings demonstrate that inducible Egr-1 expression after injury is contingent on the release and paracrine action of FGF-2.  (+info)

Evaluation of the quality of an injury surveillance system. (7/5118)

The sensitivity, positive predictive value, and representativeness of the Canadian Hospitals Injury Reporting and Prevention Program (CHIRPP) were assessed. Sensitivity was estimated at four centers in June through August 1992, by matching independently identified injuries with those in the CHIRPP database. The positive predictive value was determined by reviewing all "injuries" in the database (at Montreal Children's Hospital) that could not be matched. Representativeness was assessed by comparing missed with captured injuries (at Montreal Children's Hospital) on demographic, social, and clinical factors. Sensitivity ranged from 30% to 91%, and the positive predictive value was 99.9% (i.e., the frequency of false-positive capture was negligible). The representativeness study compared 277 missed injuries with 2,746 captured injuries. The groups were similar on age, sex, socioeconomic status, delay before presentation, month, and day of presentation. Injuries resulting in admissions, poisonings, and those presenting overnight were, however, more likely to be missed. The adjusted odds ratio of being missed by CHIRPP for admitted injuries (compared with those treated and released) was 13.07 (95% confidence interval 7.82-21.82); for poisonings (compared with all other injuries), it was 9.91 (95% confidence interval 5.39-18.20); and for injuries presenting overnight (compared with those presenting during the day or evening), it was 4.11 (95% confidence interval 3.11-5.44). These injuries were probably missed because of inadequate education of participants in the system. The authors conclude that CHIRPP data are of relatively high quality and may be used, with caution, for research and public health policy.  (+info)

Particle-mediated gene transfer of PDGF isoforms promotes wound repair. (8/5118)

Several techniques for cutaneous gene transfer have been investigated for either in vitro or in vivo applications. In the present study, we investigated whether the direct delivery of platelet-derived growth factor cDNA into skin results in improvement in tissue repair. Cutaneous transfections were carried out in rats using a particle-bombardment device (Accell). As revealed by reverse transcriptase-polymerase chain reaction, transgene expression in vivo was transient, with low level expression by day 5. When compared with wounds transfected with a control cytomegalovirus-luciferase plasmid, wounds transfected with platelet-derived growth factor A or B in the MFG vector showed a significant increase in wound tensile strength 7 and 14 d after transfection. At both time points platelet-derived growth factor A transfected wounds exhibited the highest increase in tensile strength over controls, resulting in a 3.5-fold increase at day 7 and a 1.5-fold increase at day 14. The degree of stimulation was not remarkably different between wounds transfected with platelet-derived growth factor B, which is predominantly cell associated, or a truncation mutant, platelet-derived growth factor B211, which is predominantly secreted. These findings demonstrate that in vivo gene transfer by particle bombardment can be used to improve the tissue repair response. This approach provides a robust tool to assess the biologic activity of various proteins and will aid in the development of therapeutic cutaneous gene delivery.  (+info)

Physical trauma that occurs while the mother is still pregnant may be caused by car accidents, physical abuse, or the mother taking part in physically taxing activities. Physical trauma that occurs during delivery may include excessive pressure being placed on the infants body during delivery. Improper delivery techniques that pull or jerk the infant and improper use of forceps or vacuum extractors that put strain or pressure on the infants body may also be a source of trauma.. Infant Physical Trauma after Birth. Infant physical trauma that occurs after a baby is born can be caused by many different things. Babies may be mishandled by parents, nurses, or other parties in the medical facility or after leaving the medical facility. Physical trauma can be caused by rough handling of infants, dropping infants, or subjecting infants to physically traumatic procedures. Since infants are not capable of escaping uncomfortable conditions or understanding why discomfort may be necessary, minor ...
Beginning in July 2000, the National Center for Injury Prevention and Control (NCIPC), and Centers for Disease Control and Prevention (CDC), in collaboration with the United States Consumer Product Safety Commission (CPSC), expanded the National Electronic Injury Surveillance System (NEISS) to collect data on all types and causes of injuries treated in a representative sample of United States hospitals with emergency departments (ED). This system is called the NEISS-All Injury Program (NEISS-AIP). The NEISS-AIP is designed to provide national incidence estimates of all types and external causes of nonfatal injuries and poisonings treated in United States hospital EDs. Data on injury-related visits are being obtained from a national sample of 66 out of 100 NEISS hospitals that were selected as a stratified probability sample of hospitals in the United States and its territories with a minimum of 6 beds and a 24-hour ED. The sample includes separate strata for very large, large, medium, and small ...
Beginning in July 2000, the National Center for Injury Prevention and Control (NCIPC), and Centers for Disease Control and Prevention (CDC), in collaboration with the United States Consumer Product Safety Commission (CPSC), expanded the National Electronic Injury Surveillance System (NEISS) to collect data on all types and causes of injuries treated in a representative sample of United States hospitals with emergency departments (ED). This system is called the NEISS-All Injury Program (NEISS-AIP). The NEISS-AIP is designed to provide national incidence estimates of all types and external causes of nonfatal injuries and poisonings treated in United States hospital EDs. Data on injury-related visits are being obtained from a national sample of 66 out of 100 NEISS hospitals that were selected as a stratified probability sample of hospitals in the United States and its territories with a minimum of 6 beds and a 24-hour ED. The sample includes separate strata for very large, large, medium, and small ...
Prior traumatic experiences have been associated with poorer coping strategies, greater distress, and more posttraumatic stress disorder (PTSD) symptoms following a subsequent cancer diagnosis affecting their survival. However, the impact of prior physical traumatic injury on cancer survival has not been examined. The present study matched patients from the same Level 1 Trauma center who appeared in both the trauma and cancer registries. A total of 498 patients met the criteria between 1998 and 2014 who have experienced both a diagnosis of cancer and a physical traumatic injury. The survival between the patients who had physical trauma before cancer (TBC) versus those that had physical trauma after the cancer diagnosis (TAC) were compared. The TBC group had a higher percentage of males (48 % vs 33 % p = 0.001) and motor vehicle collisions (18 % vs 7 %, p | 0.001), than the TAC group. TBC patients were also significantly younger than TAC patients at the time of the physical traumatic event (68.7 ± 14.6
Data & statistics on PROPORTION OF TRAUMATIC BRAIN INJURIES TO TOTAL INJURIES MASSACHUSETTS RESIDENTS: Traumatic Brain Injury-Related Death Rates* United States, 1996-1998, Traumatic Brain Injury-Related Death Rates* United States, 1996-1998, Traumatic Brain Injury-Related Death Rates* United States, 1996-1998...
INTRODUCTION: A significant proportion of patients suffer depression following traumatic injuries. Once manifested, major depression is challenging to overcome and its presence risks impairing the potential for physical rehabilitation and functional recovery. Risk stratification for early detection and intervention in these instances is important. This study aims to investigate patient and injury characteristics associated with an increased risk for depression.. METHODS: All patients with traumatic injuries were recruited from the trauma registry of an urban university hospital between 2007 and 2012. Patient and injury characteristics as well as outcomes were collected for analysis. Patients under the age of eighteen, prescribed antidepressants within one year of admission, in-hospital deaths and deaths within 30days of trauma were excluded. Pre- and post-admission antidepressant data was requested from the national drugs registry. Post-traumatic depression was defined as the prescription of ...
Recent studies have highlighted the importance of expeditious transfusion of plasma, platelets and red blood cells in a 1:1:1 ratio for severe trauma patients who are at risk of exsanguination. Since thawing plasma can be time-consuming, a recent study published in TRANSFUSION examined the hemostatic properties of thawed and liquid plasma over several days of storage. Briefly, during initial processing after donation 17 pooled ABO-matched plasma units were split into a liquid plasma unit and a frozen unit (subsequently thawed and stored for up to five days), and multiple hemostasis parameters, coagulation factors, and platelet activation assays were performed. A further 119 liquid plasma samples were analyzed for platelet activation and cellular content. Liquid plasma at day seven was comparable to thawed plasma at day five by every assay. However, after 11 days of storage, coagulation factors started to decline in liquid plasma, and cold-induced contact activation was observed after 28 days of ...
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Based on 8 years of nationally representative survey data, this study found that 25 of 100 children experience nonfatal injuries serious enough to require medical attention or restrict activity. This estimate is consistent with the injury rate reported by Scheidt and his colleagues,4,,29 which adjusted for the 12-month recall of injuries from the 1988 Child Health Supplement of the NHIS; by Rice et al2 from the 1984-1986 NHIS, the National Mortality Detail File, and the National Hospital Discharge Survey; and by Kogan et al30 based on the 1991 Longitudinal Follow-up to the National Maternal and Infant Health Survey. The nonfatal injury rate reported here is slightly higher than that described by Gallagher et al31 based on the 1980-1981 Massachusetts Statewide Childhood Injury Prevention Program Surveillance System (22 per 100 children). Although trends in injury rates were not our major focus, these similar injury rates across several surveys for the past 10 to 15 years suggest minimal decline ...
BACKGROUND: While there is a long history of measuring death and disability from injuries, modern research methods must account for the wide spectrum of disability that can occur in an injury, and must provide estimates with sufficient demographic, geographical and temporal detail to be useful for policy makers. The Global Burden of Disease (GBD) 2017 study used methods to provide highly detailed estimates of global injury burden that meet these criteria. METHODS: In this study, we report and discuss the methods used in GBD 2017 for injury morbidity and mortality burden estimation. In summary, these methods included estimating cause-specific mortality for every cause of injury, and then estimating incidence for every cause of injury. Non-fatal disability for each cause is then calculated based on the probabilities of suffering from different types of bodily injury experienced. RESULTS: GBD 2017 produced morbidity and mortality estimates for 38 causes of injury. Estimates were produced in terms ...
NationalElectronicInjurySurveillance Tom Schroeder 2/13System *This presentation was prepared by CPSC staff. It has not been revi…
Injury prevention/public education programs begin with the collection and analysis of population and patient data from a wide variety of sources to describe the status of injury morbidity, mortality and distribution throughout the state. Injury epidemiology is concerned with the evaluation of the frequency, rates and pattern of injury events in a population and is obtained by analyzing data from sources such as death records, hospital discharge databases and data from EMS, Emergency Departments and trauma registries. Trauma systems must develop strategies that help prevent injury as part of an integrated, coordinated and inclusive trauma system. For years, the ISDH has conducted an array of injury prevention programs. With the creation of the ISDH Trauma and Injury Prevention Division in 2011, we have shifted our focus from injury prevention programming to the collection and analysis of injury data (epidemiology) and recognized best practices in the injury field, which we can push out to those ...
With limited resources available, injury prevention efforts need to be targeted both geographically and to specific populations. As part of a pediatric injury prevention project, data was obtained on all pediatric medical and injury incidents in a fire district to evaluate geographical clustering of pediatric injuries. This will be the first step in attempting to prevent these injuries with specific interventions depending on locations and mechanisms. There were a total of 4803 incidents involving patients less than 15 years of age that the fire district responded to during 2001-2005 of which 1997 were categorized as injuries and 2806 as medical calls. The two cohorts (injured versus medical) differed in age distribution (7.7 ± 4.4 years versus 5.4 ± 4.8 years, p | 0.001) and location type of incident (school or church 12% versus 15%, multifamily residence 22% versus 13%, single family residence 51% versus 28%, sport, park or recreational facility 3% versus 8%, public building 8% versus 7%, and street
With limited resources available, injury prevention efforts need to be targeted both geographically and to specific populations. As part of a pediatric injury prevention project, data was obtained on all pediatric medical and injury incidents in a fire district to evaluate geographical clustering of pediatric injuries. This will be the first step in attempting to prevent these injuries with specific interventions depending on locations and mechanisms. There were a total of 4803 incidents involving patients less than 15 years of age that the fire district responded to during 2001-2005 of which 1997 were categorized as injuries and 2806 as medical calls. The two cohorts (injured versus medical) differed in age distribution (7.7 ± 4.4 years versus 5.4 ± 4.8 years, p | 0.001) and location type of incident (school or church 12% versus 15%, multifamily residence 22% versus 13%, single family residence 51% versus 28%, sport, park or recreational facility 3% versus 8%, public building 8% versus 7%, and street
The article introduces Programs for Injury Categorization, using the International Classification of Diseases (ICD) and R statistical software (ICDPIC-R). Starting with ICD-8, methods have been described to map injury diagnosis codes to severity scores, especially the Abbreviated Injury Scale (AIS) and Injury Severity Score (ISS). ICDPIC was originally developed for this purpose using Stata, and ICDPIC-R is an open-access update that accepts both ICD-9 and ICD-10 codes. Data were obtained from the National Trauma Data Bank (NTDB), Admission Year 2015. ICDPIC-R derives CDC injury mechanism categories and an approximate ISS (
The 2019 ThinkFirst Conference on Injury Prevention was held at the Wyndham Bayside, San Diego, April 13-14. The theme for this years conference was Charting the Course to Zero. A pre-conference training day was held April 12th, followed by a Community Helmet Event, fitting 100 people with free bicycle helmets in Waterfront Park. The Anchors Away! Reception was held Saturday evening on the Maritime Museums Berkeley Ferryboat, and the ThinkFirst Awards Luncheon was held Sunday, April 14th. ...
Injuries are the second leading cause of early death to DeKalb County residents aged 1-64. Health Promotion and Prevention Unit identifies the leading causes of injury and injury-related death to persons of all ages. Two coalitions, Safe Kids of DeKalb and Safe Communities of DeKalb, work to develop and implement prevention programs to reduce injuries and injury-related death.. Injuries can be categorized as unintentional (accidental) or intentional (deliberate). Unintentional injuries include those from motor vehicle crashes, falls, fire/smoke, poisoning and drowning. Intentional injuries include homicide, suicide and assault (violence against others).. ...
Results Drowning is the leading cause of fatal injury in Vietnamese children followed by road traffic crashes, falls, poisoning, burns and animal bites. There have been notable achievements in terms of increasing awareness of injury facing children at all levels in the community and developing a sound injury prevention policy framework in a relatively short period of time. However, much needs to be done to implement necessary environmental and legislative changes, strengthen child injury surveillance and injury prevention research; and to improve access to health services. ...
Despite reductions in youth pedestrian and bicyclist deaths over the past two decades, these injuries remain a substantial cause of morbidity and mortality for children and adolescents. There is a need for additional information on non-fatal pediatric pedestrian injuries and the role of traumatic brain injury (TBI), a leading cause of acquired disability. Using a multi-year national sample of emergency department (ED) records, we estimated annual motorized-vehicle related pediatric pedestrian and bicyclist (i.e. pedalcyclist) injury rates by age and region. We modeled in-hospital fatality risk controlling for age, gender, injury severity, TBI, and trauma center status. ED visits for pediatric pedestrian injuries declined 19.3% (95% CI 16.8, 21.8) from 2006 to 2012, with the largest decreases in 5-to-9 year olds and 10-to-14 year olds. Case fatality rates also declined 14.0%. There was no significant change in bicyclist injury rates. TBI was implicated in 6.7% (95% CI 6.3, 7.1) of all pedestrian and
Knowledge is sparse concerning injuries affecting rural populations in low and middle-income countries in general and in Iran in particular. This study documents the incidence and characteristics of severe injuries affecting rural people in the Iranian district of Twiserkan and it investigates these peoples suggestions for injury prevention and control. An interview-based investigation was undertaken that comprised all unintentional injuries leading to hospitalization (more than 6 hours) or death that had occurred within a twelve month period and that were identified in the files of the 62 health houses of the Twiserkan district. For each case, semi-structured interviews were conducted at the households of the injured people (134 injuries affecting 117 households were identified). The incidence rates of fatal and non-fatal injuries were respectively 4.1 and 17.2 per 10 000 person-years and, as expected, men were more affected than women (77.6% of all injury cases). Traffic injuries (in particular
Unintentional injuries are the leading cause of deaths among persons aged 0-19 years in the United States. Quantifying years of potential life lost (YPLL) highlights childhood causes of mortality and provides a simple method to identify important causes of premature death and specific groups in need of intervention (1). Deaths attributed to unintentional injuries among persons aged 0-19 years number approximately 12,000 each year in the United States; another 9 million young persons are treated for nonfatal injuries in emergency departments (2). To estimate the burden of premature deaths attributed to unintentional injuries among persons aged 0-19 years, CDC calculated state-specific YPLL by sex, age, race, and injury mechanism based on data from the National Vital Statistics System multiple cause of death files for the period 2000-2009. This report summarizes the results of that analysis, which found that an average of 890 years of potential life were lost each year because of unintentional ...
Background Priority setting, identification of unmet and changing healthcare needs, service and policy planning, and the capacity to evaluate the impact of health interventions requires valid and reliable methods for quantifying disease and injury burden. The methodology developed for the Global Burden of Disease (GBD) studies has been adopted to estimate the burden of disease in national, regional and global projects. However, there has been little validation of the methods for estimating injury burden using empirical data.. ...
Objectives Rest breaks and other work-related temporal factors, such as time spent on task, influence the accumulation of fatigue, and thus impact occupational injury risk. The aim of this study was to investigate the effect of rest breaks on time to injury (the time between start of work and injury) for injured workers treated in a nationally representative sample of US emergency departments.. Methods Using the National Electronic Injury Surveillance System (NEISS), we identified 629 workers who had experienced a work-related ladder-fall. Of these, 306 were interviewed by telephone using a standardized questionnaire about the circumstances surrounding the injury. Survival analyses were used to estimate time to injury, and hazard ratios (HR) for time to injury were compared between workers who reported no rest break (reference) and workers who reported rest break(s) prior to the injury (accumulated break time categorized into 0, 1-15, 16-30, and ,30 minutes). Age, gender, time of work start, ...
Injury Epidemiology is a pioneering, open access journal publishing cutting-edge epidemiologic studies of both intentional and unintentional injuries. With a ...
Green Bay Packers quarterback Aaron Rodgers explains what his injury diagnosis was at halftime in Week 1 of the 2018 NFL season against the Chicago Bears.
Updated the ICD definitions and data for non-fatal injuries in accordance with new guidance from CSTE, December 2019. Data was recalculated using the new definitions for non-fatal injury hospitalizations and emergency department visits from 2015-2018. The Non-Fatal Injury Dashboard, the Non-Fatal Injury Hospitalization Profile report and the Non-Fatal Injury Emergency Department Visits Profile report were all updated in accordance with these revisions. Injury Profile Reports ...
The CPSC estimates that there are approximately 3.2 million nonpowder guns sold yearly.12-14 Nonpowder guns are sold in many department stores, including toy stores.9 Eighty percent have muzzle velocities over 350 ft/second, and 50% have muzzle velocities between 500 and 930 ft/second. In 2000, the National Electronic Injury Surveillance System (NEISS), operated by the CPSC, collected information from a nationally representative sample of 100 US hospital emergency departments that included information on nonpowder gun injuries.. According to data from the Centers for Disease Control and Prevention ( and and the CPSC,12 in 2000 the overall nonfatal age-adjusted rate of injury from BB or pellet guns was 7.71 per 100000 population. In 2000, there were an estimated 21840 (coefficient of variation: 0.0821) nonpowder gun-related injuries treated in emergency departments (D. Tinsworth, MS, CPSC, written ...
Health Reports, volume 23, number 3. Unintentional injury hospitalizations among children and youth in areas with a high percentage of Aboriginal identity residents: 2001/2002 to 2005/2006. Table 2 Number of hospitalizations for unintentional injury, age-standardized rate, and rate ratio, by cause of injury and Dissemination Area reporting Aboriginal identity, population aged 0 to 19, Canada (excluding Quebec), 2001/2002 to 2005/2006
Although the number of unintentional injuries has decreased by almost 50% since 1990, it still continues to be the leading cause of death for children and youth (1-19 years of age) in Canada. In 2008, there were over 630 deaths due to unintentional injury in this population; over half of these due to motor vehicle accidents. Children and youth experienced over 24,000 hospitalizations (2008/09), associated with unintentional injuries: almost 40% were due to falls. Many of these non-fatal injuries result in impairments and disabilities such as blindness, spinal cord and brain injuries Child and Youth Injury in Review, 2009, (Public Health Agency of Canada).. Among seniors, unintentional injuries are the 8th leading cause of deaths overall, and the 5th leading cause of hospitalizations. Within the unintentional injury category, falls are the leading cause of both injury deaths and hospitalizations for seniors Injury Prevention for Seniors, (Public Health Agency of Canada).. ...
Pediatric Annals | There is renewed vigor in accident research relating to the etiology and prevention of severe trauma.1. INJURY SURVEILLANCEFundamental accident data, investigations and analyses are being provided by the National Electronic Injury Surveillance System (NEISS).1,2 This innovative program, based on a pilot study of the National Commission on Product Safety, was fully developed by the Bureau of
The science and policy of preventing injuries, reducing disability, and providing emergency services and rehabilitation is studied in this area of specialization.. In conjunction with the Center for Injury Research and Policy, the faculty and students focus on injuries of all types, including road traffic injuries, falls, burns, drowning and violence. The epidemiology of these injuries is assessed, and strategies to prevent injuries are formulated and evaluated. Students completing this specialization may also decide to complete the Certificate in Injury and Violence Prevention. Please contact the director of the certificate, Dr. Keshia Pollack, for more information.. Students must complete the course requirements for the concentration in Health and Public Policy and, in addition, take the following courses. ...
The study authors tracked injury events (an injury was an incident that caused 3 consecutive missed runs) and pain with running at several points during the 12-week duration of the experiment.. Study Results. A total of 23 injuries were reported by the 99 runners over the 12-week training period (injury incidence = 23.2%). Injury results among groups were distributed as follows: 4/32 (13%) in the Nike Pegasus got injured, 12/32 (38%) in the Nike Free 3.0v2 got injured, 7/35 (20%) in the VFF Bikila group got injured. Injury risk was significantly higher in the Nike Free group compared to both the Vibram and Nike Pegasus groups. Risk of injury was not not significantly different between the Vibram and Nike Pegasus groups.. Results for pain during running were mostly non-significant, with only calf/shin pain in full minimalist runners being significantly higher.. Based on a statistical analysis of the results, the authors conclude Based on injury event data, there is a higher likelihood of ... WEBINAR DESCRIPTION. Researchers who study injury morbidity frequently use hospital discharge, emergency department, trauma registry or other datasets that have been coded using the clinical modification (CM) of the International Classification of Diseases (ICD). In October 2015, ICD-10-CM replaced ICD-9-CM as the coding schema used by hospitals and health care providers to report medical information. With the transition to ICD-10-CM, injury researchers face new opportunities and challenges in data analysis due to the increased number and complexity of the ICD-10-CM codes. This webinar will provide an overview of the ICD-10-CM injury codes and the tools that have been developed for standardized categorization of injuries by mechanism and intent of injury and by nature of injury and body region (the proposed ICD-10-CM External Cause and Injury Diagnosis matrices). Proposed ICD-10-CM surveillance case definitions, including the ...
Between 1990 and 2010, more than 260,000 children were treated in emergency departments (EDs) for ear injuries related to use of cotton-tip applicators (CTAs), according to data from the National Electronic Injury Surveillance System.
There are various reasons for spinal injuries and related problems which can make your living difficult. Based on the severity of the injury there is a need to make some changes to their lifestyle. Severe spinal injuries can make the person paralyzed, and they may require personal care even when he returns to his house after the treatment. These people require the need of changing the facilities of their house based on the comfort of the injured people. The home stairlifts in Los Angeles offer proper adaptations to help the injured people to ensure their safety. The link lists some of the important tips to take care of the older adults in your house.. The article explains in detail the spinal cord injuries and the treatment offered to the injured people. It also gives an idea of the changes to be made to your house so that it makes the injured people move around in their house.. The spine of the human body is made of bone, which is divided into three ...
Unintentional injuries are tracked by the Centers for Disease Control and Prevention (CDC) through the Injury Center, and reported at WISQARS(TM).[fn]Web-based Injury Statistics Query and Reporting System: Accessed December 24, 2014.[/fn] Injuries kill thousands every year, and many of those who survive have life-long impairment as
One of the first things youll want to do is to make sure that you are seeking the assistance of a professional counsellor if you are having a lot of recurring emotional problems related to your accident. For example, if you have a major fear of getting back into a vehicle after someone crashed into you, you will want to get professional emotional help. For the time being, you might even be able to find a mobile therapist who can come to you until you are able to travel again. If you dont get the emotional help you need, you may find that the problems are only going to get a lot worse.. You might also be able to receive some emotional help from support groups, both in person and online. This will give you the chance to talk with others who are also struggling a lot after they experienced a traumatic injury. You can learn from one another and simply be there to lend an ear whenever someone needs to vent some.. As you can see, it will take some work to heal from all of the physical, financial, ...
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. ...
In recent months Thompson Coburn has continued its longtime litigation work on behalf of Yamaha Motor Corporation USA, with two successful case resolutions in August.
When prevention efforts fail, injured children require high-quality health services to support their recovery. Disparities in non-fatal injury outcomes, an indicator of health-care quality, have received minimal attention. We evaluated the extent to which general trauma follow-up studies published in the peer-reviewed scientific literature provide evidence of socially patterned inequities in health, functional or disability outcomes ≥4 weeks after childhood injuries. Using a systematic search, we identified 27 eligible cohort studies from 13 high-income countries. We examined the extent to which the reported health outcomes varied across the PROGRESS criteria: place of residence, race/ethnicity, occupation, gender/sex, religion, socio-economic status, and social capital. The available evidence on differential outcomes is limited as many studies were compromised by selection or retention biases that reduced the participation of children from demographic groups at increased risk of adverse outcomes, or
The preventing unintentional injuries among under-15s: local authorities path for the unintentional injuries among under-15s pathway.
After a person has been in a car accident, they are understandably in shock. Car accidents happen quickly, oftentimes before either party had time to react. For those who have been injured in a car accident, most of the trauma often ends up being in the head and neck, although cars with airbags are supposed to protect on impact.
In Canada, there are many formal public health programs under development that aim to prevent injuries in the early years (e.g. 0-6). There are paradoxically no population-based studies that have examined patterns of injury by developmental stage among these young children. This represents a gap in the Canadian biomedical literature. The current population-based analysis explores external causes and consequences of injuries experienced by young children who present to the emergency department for assessment and treatment. This provides objective evidence about prevention priorities to be considered in anticipatory counseling and public health planning. Four complete years of data (1999-2002; n = 5876 cases) were reviewed from the Kingston sites of the Canadian Hospitals Injury Reporting and Prevention Program (CHIRPP), an ongoing injury surveillance initiative. Epidemiological analyses were used to characterize injury patterns within and across age groups (0-6 years) that corresponded to normative
SAN ANTONIO, June 15 /PRNewswire-USNewswire/ -- National Trauma Institute Seeks Trauma Studies Eligible for $2.8 Million in Research Funding.
Sports injury prevention is a priority area in BJSM 1 and recent commentaries have stressed the need to consider relationships between sports injuries in longitudinal data sets.2 ,3 Players can sustain none, one, or more than one injury over a season of follow-up. Subsequent injuries are statistically related to prior injuries because they occur in the same person. This is true even when the two injuries are clinically distinct.2 ,4 ,5 It is always important to collect, analyse and report data on subsequent injuries in injury incidence studies. Figure 1 shows a hypothetical cohort of five players followed over one season of 10-week duration. This example assumes that all players are injury-free at the start of the season and addresses acute onset injuries rather than those due to repetitive microtrauma. The figure contains considerable information on each player: how long they were followed up; the number of injuries they sustained; how long before they sustained their first injury; and how long ...
Thanks to incredible developments in the world of medical diagnostics, it is now far quicker to identify and treat problems such as sports and other injuries.
Data & statistics on Mortality rate from alcohol-related motor vehicle injuries New: Mortality rate from alcohol-related motor vehicle injuries, New Jersey, 1999, 2003, ALCOHOL-RELATED, DRUG-RELATED, AND INJURY DEATHS BY COUNTY OF RESIDENCE NEW JERSEY, 1999 MOTOR VEHICLE INJURIES, Does not include the contribution of alcohol to deaths from road traffic injuries, other injuries, cancer, cardiovascular diseases and other conditions. It is estimated that in 1996, 30 per cent of all drinkers killed in motor vehicle crashes had alcohol levels above the legal limit....
INTRODUCTION: injuries represent a significant cause of morbidity and mortality worldwide and road traffic crashes accounts for a significant proportion of these injuries. Tanzania is among the countries with high rates of road traffic crashes. The aim of this study was to determine the pattern, associated factors and management of road traffic injury patients in Tanzania. METHODS: a cross-sectional study of patients involved in motor traffic crashes and attended in six public hospitals of Tanzania mainland between April 2014 and September 2014. RESULTS: a total of 4675 road traffic injury patients were seen in studied hospitals, 76.6% were males. Majority (70.2%) were between 18 - 45 years age group. Motorcycles were the leading cause of road traffic crashes (53.4%), and drivers (38.3%) accounted for majority of victims. Fractures accounted for 34.1%, and injuries were severe in 2.2% as determined by the Kampala trauma score II (KTS II). Majorities 57.4% were admitted and 2.2% died at the casualty.
Falls are the leading cause of nonfatal injuries in the United States. In 2006, nearly 8 million persons were treated in emergency departments (EDs) for fall injuries (1). Pets might present a fall hazard (2), but few data are available to support this supposition. To assess the incidence of fall-related injuries associated with cats and dogs, CDC analyzed data from the National Electronic Injury Surveillance System All Injury Program (NEISS-AIP) for the period 2001--2006. This report describes the results of that analysis, which showed that an estimated average of 86,629 fall injuries each year were associated with cats and dogs, for an average annual injury rate of 29.7 per 100,000 population. Nearly 88% of injuries were associated with dogs, and among persons injured, females were 2.1 times more likely to be injured than males. Prevention strategies should focus on 1) increasing public awareness of pets and pet items as fall hazards and of situations that can lead to fall injuries and 2) ...
Bethlehem, PA, November 3, 2020, ZEXPRWIRE - Cordisco & Saile LLC, personal injury lawyers in the Lehigh Valley have taken a new initiative to proving traumatic brain injury cases in Pennsylvania. The new focus is meant to help residents of Lehigh County and Northampton County overcome the legal challenges involved in seeking compensation in brain injury cases.. In a recent radio interview, John F. Cordisco, Esq., a founding partner at Cordisco & Saile, described Traumatic Brain Injury (TBI) as a serious and debilitating head injury that often results from automobile, trucking, and motorbike accidents as well as from slips, falls, and trips. The problem is that TBI, which is often called the invisible injury is not easy to identify and prove in court. Personal injury claims with severe head injuries and severe brain damage involve skull fractures, coma, and brain bleeds. However, mild brain injuries, which have serious long-term consequences, are not always given the same attention as severe ...
Bethlehem, PA, November 3, 2020, ZEXPRWIRE - Cordisco & Saile LLC, personal injury lawyers in the Lehigh Valley have taken a new initiative to proving traumatic brain injury cases in Pennsylvania. The new focus is meant to help residents of Lehigh County and Northampton County overcome the legal challenges involved in seeking compensation in brain injury cases.. In a recent radio interview, John F. Cordisco, Esq., a founding partner at Cordisco & Saile, described Traumatic Brain Injury (TBI) as a serious and debilitating head injury that often results from automobile, trucking, and motorbike accidents as well as from slips, falls, and trips. The problem is that TBI, which is often called the invisible injury is not easy to identify and prove in court. Personal injury claims with severe head injuries and severe brain damage involve skull fractures, coma, and brain bleeds. However, mild brain injuries, which have serious long-term consequences, are not always given the same attention as severe ...
Injuries are noted to be an important cause of death among adolescents. There is however limited data on the injury related deaths among adolescents in Ghana. Using data from post-mortem records derived from the Department of Pathology of the Korle-Bu Teaching Hospital (KBTH), Accra Ghana from 2001 to 2003, the causes of injury related deaths among adolescents 10 to 19 years were analyzed by gender and age groups 10 to 14 and 15 to 19 years. There were 151 injury-related deaths constituting 17% of the autopsies performed among adolescents in the study period. The male-to-female ratio was 2.1:1. Drowning was the most common cause of death (37%) in the study population. This was followed by road traffic accidents (RTA) (33%). Over 70% of the RTA victims were pedestrians knocked downed by a vehicle. Deaths from electrocution, poisoning, burns, stab/gunshot, hanging and other miscellaneous causes (example blast injury, traumatic injury from falling debris, fall from height) made up the remaining 30% of the
The experiences of nurse in providing psychosocial support to families of critically ill trauma patients in the intensive care unit
Workplace Injury Statistics in Chicago, IL The Bureau of Labor Statistics (BLS) has released its data for workplace injury statistics, showing that the overall
Some people may think that both are one and the same. However, physical injuries and psychological injuries are different from each other, each in their own prospective ways. Physical vs psychological injuries - what are the differences? Please read on to learn more. You will be glad you did. The causes for physical injuries can be numerous in definition. These are just a few examples of the many causes that are possible for them.. What are physical injuries? How do they happen? Physical injuries are something that happen as the result of an accident, from a sport, or some other form of physical activity. Physical injuries can occur in car accidents, industrial or on the job site accident, or due to a slip and fall incident. When accidents of this type happen to someone, he or she is unable to physical enjoy their own properly or life, and this can prove to be very devastating to the victim in a number of ways personally.. Physical injuries can also end up becoming the basis for a personal ...
Participation in high school athletics carries an intrinsic risk of injury, but that doesnt mean certain types of injuries cant be decreased. There has been a proliferation of injury prevention programs. These programs have the ability to improve performance and decrease risk of sustaining certain injuries, especially ACL injuries and ankle sprains. While this information is readily available, there has been some hesitancy to adopt these and similar programs.. In an Oregon survey of high school soccer and basketball coaches, many of the coaches were aware that injury prevention programs existed, but they were not adopting those programs for their own teams.1 Some of their reasons included the belief that what they currently did was similar to the program; their program was superior to the researched program; or they were not aware of how much actual sport performance gains occurred as a result of these programs. Those concerns have validity and merit further discussion.. Many injury programs ...
UH Rainbow Babies & Childrens Hospital has received re-verification as a Level I pediatric trauma center from the American College of Surgeons (ACS) Committee on Trauma (COT). UH Rainbow Babies & Childrens Hospital has been a continuously verified Level I pediatric trauma center for more than two decades, and is the only designated Level I pediatric trauma center in northern Ohio.. We are proud to once again be recognized as a Level I pediatric trauma center by the American College of Surgeons Committee on Trauma, said Mike Dingeldein, MD, Medical Director of the pediatric trauma center at UH Rainbow Babies & Childrens Hospital.. A Level I pediatric trauma center offers the highest level of trauma care across the continuum from injury prevention through rehabilitation. At UH Rainbow Babies & Childrens Hospital, board-certified trauma surgeons, supported by pediatric nurses and a pediatric emergency department team specially trained in the care of injured children, are all ready to respond ...
Fellowship overview. As a member of ACDSB, the Service Fellow will contribute to all aspects of the branch mission, including planning and conducting research studies in injury epidemiology in such areas as emerging trends in injury morbidity and mortality, health disparities related to injury, the effects of injury on health outcomes and utilization of health care services, and social and physical functioning post-injury. In collaboration with other members of ACDSB and other NCHS staff, the Fellow is expected to plan and carry out high-quality research by selecting appropriate statistical and epidemiologic methods, independently conducting statistical analysis using standard programming software, utilizing large-scale NCHS data sources, and disseminating results via NCHS reports and articles in scientific journals. Qualifications. This fellowship is open to all citizens of the United States and legal permanent residents with a work authorization. Applicants must have successfully completed a ...
States with low nonfatal injury rates and high fatality rates tend to be in the South, have lower worker compensation benefits, be less unionized, and pay lower wages—while states with high nonfatal injury rates and lower fatality rates tend to be in the West, pay higher benefits and wages, be more strongly unionized, and carry out more workplace inspections.
Issue 4 Injuries in the European Union Summary of injury statistics for the years Working together to make Europe a safer place Issue 4 Injuries in the European Union Summary of injury statistics
June 2004-. Violent behavior among adolescents is a significant problem worldwide, and a cross-national comparison of adolescent violent behaviors can provide information about the development and pattern of physical violence in young adolescents. Smith-Khuri and colleagues examined frequencies of adolescent violence-related behaviors in 5 countries and associations between violence-related behaviors and potential explanatory characteristics.. A significant body of information currently exists describing violent behavior in the adolescent population of the United States, yet violent behavior in adolescents outside and in relation to the United States is not well characterized. Comparison of violence-related behaviors in US youths with those of their peers in other countries can provide a context for the US findings. Our analysis found that for 3 violence-related behaviors-fighting, weapon carrying, and injuries from fighting-adolescents from 5 European countries were remarkably similar in ...
Background: This paper aims at assessing the effectiveness of introducing road safety onto the political agenda in the year 2004 - and the overall effect of the road safety measures implemented thereafter - on the number of road traffic injured people in Spain. Methods: An evaluation study was performed using an interrupted time-series design. The study population were people injured in road traffic crashes in Spain between the 1st of January 2000 and the 31st of December 2006. The road traffic crashes database of the General Directorate for Traffic was used. The dependent variable was the monthly number of people injured, stratified by sex, age, severity and type of road user. The explanatory variable (intervention) compared the post-intervention period (2004-2006) with the pre-intervention period (2000-2003). Quasi-Poisson regression models were adjusted, controlling for time trend and for seasonality. Results: Results show a reduction in the risk of being injured for both men (RR=0.91; 95%CI: ...
As many as half of all patients with major traumatic injuries do not receive the recommended care, with variance in preventable mortality reported across the globe. This variance highlights the need for a comprehensive process for monitoring and reviewing patient care, central to which is a consistent peer-review process that includes trauma system safety and human factors. There is no published, evidence-informed standardised tool that considers these factors for use in adult or paediatric trauma case peer-review. The aim of this research was to develop and validate a trauma case review tool to facilitate clinical review of paediatric trauma patient care in extracting information to facilitate monitoring, inform change and enable loop closure. Development of the trauma case review tool was multi-faceted, beginning with a review of the trauma audit tool literature. Data were extracted from the literature to inform iterative tool development using a consensus approach. Inter-rater agreement was assessed
On average across the years from 2011 to 2013, 1.8 million injuries per year related to team or individual sport activities occurred to children and adolescents age 20 years and younger. Data reported is from consumer product-related injuries occurring in the United States from a statistically valid sample of emergency departments collected by the United States Consumer Product Safety Commission, National Electronic Injury Surveillance System. Data shown for sports injuries are not included in the overall total for musculoskeletal conditions among children and adolescents, on the assumption it duplicates numbers found in the emergency department database based on ICD-9-CM codes and used in the trauma injuries section.. Males report injuries at twice the number as females, with the highest number of injuries occurring in the junior high (11 to 13 years) and high school (14 to 17 years) ages. (Reference Table 7.7.1 PDF CSV). ...
Doylestown, PA, November 3, 2020, ZEXPRWIRE - Leading Bucks County injury law firm, Cordisco & Saile, recently announced their new initiative on handling traumatic brain injury cases for residents of Bucks County and beyond. The new focus puts into consideration the fact that traumatic brain injuries, whether minor or serious, have lifetime consequences and costs as other serious diseases. According to reports by the Centers for Disease Control and Prevention (CDC), more than 2.8 million people in the United States suffer from traumatic Brain Injury (TBI) every year. TBI has been proven to be a major cause of disability and death in the US. The CDC further notes that despite the fact that most TBI injuries may not seem to be life-threatening at first, the injuries can potentially lead to temporary or permanent impairment of brain function over time and leave the victim in a state of debilitation. Traumatic brain injuries or brain damage is often called the invisible injury says managing ...
Unsure about the birth injury diagnosis of your child? Prince Georges County birth injury lawyer Marcus Boston explains actions to take if you question...
Safe Kids Northern New Jersey is a community-based Injury Prevention Coalition located within Morristown Medical Centers Trauma Services. Its mission is to reduce fatalities, injuries and property damage from unintentional bodily harm that occurs to children of all ages on the road, at home and while at play. KJ Feury, APN, coordinator of the coalition, discusses what everyone needs to know about stepping up safety and prevention to protect family and loved ones.. Q: Why, as a culture, are we so accident prone?. A: This isnt the case. Were not accident prone at all. We make decisions that can have negative outcomes and cause intentional injury. A decision to speed, drive under the influence or participate in a winter sport such as skiing or snowboarding without wearing a helmet puts ourselves and others at risk of injury.. Q: What are the most frequent accidents that occur with children?. A: Motor vehicle crashes are the leading cause of death in children ages 5 to 9 years old, while drowning ...
Using Caroline Finch`s Tripp model1 (Translating Research into Injury Prevention Practice) as a framework, a working group was established to produce a strategy to reduce ACL injuries. This group included elite coaches, orthopaedic knee surgeons, medical staff working with teams and representatives of the GAA. They considered incidence and aetiology of ACL injuries in GAA athletes2 as well as important contextual and sport-specific factors that may influence the effectiveness of an injury prevention programme. The working group agreed that an injury prevention warm-up was the best approach in order to facilitate effectiveness to the wider GAA population. They also recognised that this programme needed to be coach led and embedded in normal training practices.. Modelled on the successful FIFA 11+ programme, the working group designed a sport specific warm up. Initial versions of the warm-up were trialled by athletes and coaches and refined several times to ensure the final product worked in a ...
Anterior cruciate ligament (ACL) Injury diagnosis (costs for program #182411) ✔ University Hospital Giessen UKGM ✔ Department of Orthopedics and Orthopedic Surgery ✔
Anterior cruciate ligament (ACL) Injury diagnosis (costs for program #98303) ✔ Hirslanden Salem-Spital ✔ Department of Orthopedics ✔
PubMedID: 25398596 | Actual versus ideal body weight for acute kidney injury diagnosis and classification in critically Ill patients. | BMC nephrology | 11/15/2014
The WHO estimates that over 1.2 million people die each year on the worlds roads, and between 20 and 50 million fall victim to non-fatal injuries.1 The WHO projects that, unless immediate action is taken, traffic crashes will increase from the ninth to the fifth leading cause of death by 2030, and will then cause around 2.4 million deaths per year.1 Road traffic injuries (RTI) are also projected to rise to the third leading cause of disability-adjusted life years (DALYs) lost worldwide by 2020.2 The burden of traffic crashes, in terms of mortality and morbidity, is increasing fastest in developing countries, due to rapid motorisation associated with economic growth.3 ,4. The situation is particularly acute in India, a nation of more than 1 billion people, with one of the fastest growing economies in the world. This economic growth has also meant a rapidly increasing number of vehicles sold every year (around 6 million) and one of the highest reported mortality rates from RTI in the world.5 Road ...
The home is a principal setting for injury mortality and morbidity, especially for those younger than 15 years of age.1 The specific types and causes of childhood injuries vary according to age and development. Fires and burns, inhalation and suffocation and drowning are the leading causes of unintentional home injury death while … ...
Critical Behavior Monitoring for Children with Special Needs in Preventing Physical Injury Using Kinect: 10.4018/978-1-4666-7373-1.ch011: This research studies ways to prevent physical injury for children with special needs, or specifically children with Autism Spectrum Disorder (ASD). The
Currently, injury in India is a leading cause of years of productive life lost and the leading cause of death for those under 35 years old. This national injury burden is growing and the ongoing rise in the trauma burden is mostly in the form of road traffic crashes. India has 1% of the total vehicles in the world yet accounts for 6% of total road accidents globally. It is estimated that there are 400 000 road traffic crashes in India each year, resulting in 100 000 deaths and 1.2 million individuals who are seriously injured. The burden is borne disproportionately by young people with a regional report concluding a total of 6134 life years were lost each year in a population of 108 000 following unintentional injuries.8 International establishment of trauma systems incorporating centralised trauma centres has helped address the injury burden by providing prompt, specialist trauma care. In such systems, effective therapy for the severely injured is facilitated by an interdisciplinary and ...
Needs Assessment/Gap: The Ohio Chapter, American Academy of Pediatrics conducted a survey in the fall of 2011 that asked pediatricians about their experience and views on injury anticipatory guidance, counseling and product distribution. One of the surveys major findings indicated that less than 20% of physicians have received special training on injury prevention strategies or methods. With a lack of knowledge on injury anticipatory guidance, as well as an apparent lack of time to address these topics, the Injury Prevention Learning Collaborative aims to provide practices with tools to help identify the areas where guidance is needed, as well as provide concise talking points that allow providers to address issues in a short period of time. As adolescent health becomes a forefront issue in pediatrics, physicians have noted a gap in knowledge relating to teen driving, water safety, fire arms, bullying, and sports injury/concussions.. The Ohio Chapter, American Academy of Pediatrics (Ohio AAP) ...
Section 515.2045 Level II Pediatric Trauma Center a) The Level II Pediatric Trauma Director shall advise the Trauma Center Medical Director and shall be a member of the Regional Trauma Advisory Board. b) The Pediatric Trauma Center Medical Director shall be board certified in pediatric surgery or be a general surgeon, with at least two years of experience in pediatric trauma care, and have 10 hours per year of trauma-related CME, and 24-hour independent operating privileges, as evidenced by either: 1) responsibility for 50 pediatric trauma cases per year; or 2) both: A) responsibility for 10 percent of the total number of pediatric trauma cases at the trauma center per year; and B) ongoing involvement in pediatric trauma care. c) The trauma center shall provide a pediatric trauma service separate from the general surgery service. The pediatric trauma service shall be staffed by pediatric trauma surgeons who have one year of experience in trauma, who have 24-hour independent operating privileges, ...
Unfortunately, spinal cord injuries can change a persons life forever. This is why it is essential for an injured person to contact a lawyer who is experienced in presenting evidence in a Carrollton spinal cord injury case. Call today to see how an attorney can help.
TY - JOUR. T1 - Excess mortality caused by medical injury. AU - Meurer, Linda N.. AU - Yang, Hongyan. AU - Guse, Clare E.. AU - Russo, Carla. AU - Brasel, Karen J.. AU - Layde, Peter M.. N1 - Copyright: Copyright 2009 Elsevier B.V., All rights reserved.. PY - 2006/9. Y1 - 2006/9. N2 - PURPOSE: We wanted to estimate excess risk of in-hospital mortality associated with medical injuries identified using an injury surveillance system, after controlling for risk of death resulting from comorbidities. METHODS: The Wisconsin Medical Injuries Prevention Program (WMIPP) screening criteria were used to identify medical injuries, defined as any untoward harm associated with a therapeutic or diagnostic healthcare intervention, among discharge diagnoses for all 562,317 patients discharged from 134 acute care hospitals in Wisconsin in 2002. We then derived estimates for crude and adjusted relative risk of in-hospital mortality associated with the presence of a medical injury diagnosis. Logistic regression ...
TY - JOUR. T1 - Improving outcomes in pediatric trauma care. T2 - Essential characteristics of the trauma center. AU - Knudson, M. Margaret. AU - McGrath, Jennifer. PY - 2007/12. Y1 - 2007/12. N2 - The best outcome after pediatric injury can be anticipated when the entire trauma team is prepared, knowledgeable, and appreciative of the unique aspects of pediatric trauma and pays strict attention to all aspects of the care of the injured child. Five aspects should be considered essential elements in the delivery of care by any trauma team: preparation, equipment, and training; prevention of secondary insults after brain injury; the ability to recognize when nonoperative therapy should not be attempted or when it should be abandoned; consideration of the psychological impact of injury on a child; and, the role of trauma centers in injury prevention. Each of these areas encompasses important unanswered questions.. AB - The best outcome after pediatric injury can be anticipated when the entire trauma ...
Early appreciation of major trauma enables emergency medical service (EMS) providers to match the available resources to each victims needs. Triage is the process of classifying patients according to injury severity and determining the priority for further treatment [1, 2]. Field triage has become increasingly important, as regionalised trauma care with dedicated trauma teams has been shown to improve patient outcome [3-5]. Nevertheless, some mistriage is unavoidable, as field triage is performed close to the time of injury, with limited diagnostic resources in a multifarious pre-hospital environment. If major trauma victims are undertriaged and therefore denied access to high-resource resuscitation, avoidable negative outcomes may ensue [1, 6]. Conversely, overtriage may cause minor trauma victims to be unnecessarily transferred to dedicated trauma care facilities, thereby consuming scarce financial and human resources. Overtriage thus decreases the available resources for other patients with ...
Injuries are the leading cause of death for children and adolescents 1-21 years of age. The Maternal, Child and Adolescent Health Division in collaboration with the Safe and Active Communities Branch works to incorporate injury prevention interventions into local programs and services to enhance the safety of Californias children ...
Background The current common and dogmatic opinion is that whole-body computed tomography (WBCT) should not be performed in major trauma patients in shock. We aimed to assess whether WBCT during trauma-room treatment has any effect on the mortality of severely injured patients in shock. Methods In a retrospective multicenter cohort study involving 16719 adult blunt major trauma patients we compared the survival of patients who were in moderate, severe or no shock (systolic blood pressure 90-110,|90 or |110 mmHg) at hospital admission and who received WBCT during resuscitation to those who did not. Using data derived from the 2002-2009 version of TraumaRegister®, we determined the observed and predicted mortality and calculated the standardized mortality ratio (SMR) as well as logistic regressions. Findings 9233 (55.2%) of the 16719 patients received WBCT. The mean injury severity score was 28.8±12.1. The overall mortality rate was 17.4% (SMR = 0.85, 95%CI 0.81-0.89) for patients with WBCT and 21.4%
1) CFOI has used several versions of the North American Industry Classification System (NAICS) since 2003 to define industry. For more information on the version of NAICS used in this year, see our definitions page at (2) Workers under the age of 16 years, volunteer workers, and members of the resident military are not included in rate calculations to maintain consistency with the Current Population Survey (CPS) employment. The ownership category government is not presented separately and may be included in any industry category. In 2007, the Census of Fatal Occupational Injuries (CFOI) adopted hours-based state fatal injury rates. Employment-based rates were used previously. Because of substantial differences between rates calculated using the two methods, hours-based state fatal injury rates should not be compared to the employment-based rates from previous years ...
Coroners made recommendations about the prevention of harm in 53 of the 3289 (1.6%) external cause deaths of nursing home residents. Recommendations were most frequently made for deaths resulting from falls; however, the rate of recommendations per 1000 deaths was highest for thermal mechanisms and complications of clinical care. Most recommendations described the countermeasure element, but rarely specified a timeframe for implementation ...
Globally, injuries cause more than 5 million deaths annually, a similar number to those from HIV, Tuberculosis and Malaria combined. In people aged between 5 and 44 years of age trauma is the leading cause of death and disability and the burden is highest in low- and middle-income countries (LMICs). Like other LMICs, injuries represent a significant burden in Nepal and data suggest that the number is increasing with high morbidity and mortality. In the last 20 years there have been significant improvements in injury outcomes in high income countries as a result of organised systems for collecting injury data and using this surveillance to inform developments in policy and practice. Meanwhile, in most LMICs, including Nepal, systems for routinely collecting injury data are limited and the establishment of injury surveillance systems and trauma registries have been proposed as ways to improve data quality and availability. This study will implement an injury surveillance system for use in emergency
Traumatic injury[edit]. Traumatic bleeding is caused by some type of injury. There are different types of wounds which may ... See also: Emergency bleeding control, Wound healing, and Wound bed preparation. Acute bleeding from an injury to the skin is ... The pattern of injury, evaluation and treatment will vary with the mechanism of the injury. Blunt trauma causes injury via a ... Wounds are often not straight and unbroken skin may hide significant injury. Penetrating trauma follows the course of the ...
Wounded in action[edit]. Main article: Wounded in action. Shell fragment injury, American Civil War ... Military Medical Casualties are losses during wars of armed forces personnel on account of wounds or other effects received ... The former refers to casualties that are the result of wounds, trauma, burns, ionizing radiation contamination, poisoning, and ... In military usage, a casualty is a person in service killed in action, killed by disease, disabled by injuries, disabled by ...
614 Forensic medicine; incidence of injuries, wounds, disease; public preventive medicine. *615 Pharmacology and therapeutics ...
Died of wounds and injuries: 120[70]. *Wounded in action: 1,926[70] ... Troops of the 511th Parachute Infantry Regiment evacuate a wounded soldier to an aid station at Manarawat on the island of ... Priority during loading was given to the women, children and wounded; some of the able-bodied men walked alongside the Amtracs ... personally killing twenty-seven Japanese soldiers before being mortally wounded by a sniper.[31] The regiment was ordered to ...
Stab wounds inside her mouth. *Crush injuries to both hands. *Mutilation of her ears, nose, eyebrows, mouth, lips and genitalia ... I have examined almost 600 victims of homicide but I have never come across injuries so extensive."[4] The following injuries ... Her blood was found throughout the house, and a post-mortem examination revealed over 150 separate injuries on her body. During ... Multiple stab wounds caused by knives, forks and scissors. * ... Wounds caused by a spade and pruning shears. *Both eyes gouged ...
Jean Lemaitre, A Course on Damage Mechanics (2013). "Wounds and Injuries: MedlinePlus". Retrieved 2015-07-20. " ... In law, damages are the award, typically of money, to be paid to a person as compensation for loss or injury (i.e., economic or ... Damage to a living organism may be referred to as an injury. The kinds of damage experienced by living things range from ... and criminal law codices have many provisions to protect individuals against injuries caused by institutions to which they are ...
"Gunshot Wounds: 1. Bullets, Ballistics, and Mechanisms of Injury". American Journal of Roentgenology vol.155 no. 4: 685-690. ... "Firearms Tactical Institute-Wound Ballistics". Wound Ballistics. "The Gun Zone". Handgun Wounding Factors. Archived from the ... This is because it acts to stretch the permanent cavity, increasing the wounding potential. The potential for wounding via ... For comparison, rifles wound through temporary cavitation as well as permanent cavitation. A temporary cavity is also known as ...
Wounds and injuries 98-98.4....................................Surgical complications 99-99.35 ...
Marshal Morgan Earp were both seriously wounded. Goodfellow treated both men's injuries. Goodfellow treated Virgil Earp again ... In the US and Britain skeletal injuries are treated by trauma orthopedic surgeons. Facial injuries are often treated by ... washing the patient's wound and his hands with lye soap or whisky. He became America's leading authority on gunshot wounds and ... Most injuries requiring operative treatment are musculoskeletal. For this reason, part of US trauma surgeons devote at least ...
Seven people were wounded when a rocket struck the Eshkol region. A barrage of rockets was fired at Sdot Negev and two rockets ... No injuries were reported. This was the first time that Gush Dan has been targeted by missiles since the Persian Gulf War, when ... An explosion on a bus in Tel Aviv wounded at least 28 people, including three seriously. The blast on the bus occurred in an ... The attacks included an airstrike on Khan Younis, in the Southern Gaza Strip, that led to the injury of four people including a ...
She suffered facial wounds and orthopaedic injuries.[6] In popular culture[edit]. Narain appeared alongside Leonardo DiCaprio ...
Wounds or injuries that aren't completely disabling. Referred to as "walking wounded." ... The system allows for caregivers to prioritize patient's wounds and injuries in order to get those who are severely injured ... This proved to be highly successful; during the Korean War, a seriously wounded soldier who made it to a MASH unit alive had a ... Military doctors stabilized wounded soldiers midair, before getting them to field hospital. MASH onsite paramedic care and air ...
Management of trauma and injuries. Epidemiology[edit]. The Center for Disease Control in the U.S., and its corresponding ... Improvised field wound management. *Improvisational medical techniques in the wilderness. Disaster and humanitarian assistance[ ... preliminary treatment of acute injuries or illnesses which occur in those environments and the emergency evacuation of victims ...
Wound Healing, Growth Factors. *After the Injury- Children's Hospital Of Philadelphia ... Wound healing[edit]. Main article: Wound healing. In response to an incision or wound, a wound healing cascade is unleashed. ... It even allows some mammals (like mice) to heal wounds without scars.[4][5] The LIN28 gene also plays a role in wound healing. ... Wound Healing and Repair. *Lorenz H.P. and Longaker M.T. Wounds: Biology, Pathology, and Management. Stanford University ...
Most injuries were from gunshot wounds. Bodies have been described as unidentifiable due to their mutilation. Due to the ...
Three wounded patients were evacuated to the hospital, where two children were later declared dead. The other was an ... "Medical Examiner: Newtown Shooting Victims Suffered 'Devastating Set of Injuries'". December 15, 2012. ... Hammond was hit first in the leg, and then sustained another gunshot wound. She lay still in the hallway and then, not hearing ... Carver, who performed autopsies on seven of the victims, said the wounds he knew about were caused by a "long weapon" and that ...
He succumbed to his injuries on February 5, 2002. "Philadelphia mobster dies from gunshot wounds". Arizona Daily Sun. "Raymond ... Martorano was shot and critically wounded by an unknown gunman or gunmen. ...
Nine of the 30 GIGN operatives received injuries; of them, one received serious wounds. Three crew members received injuries. ... Bossuat received minor injuries; the dead bodies of two hijackers had shielded Delhemme and Bossuat from gunfire. Borderie, the ... Favier said that he determined that the operation was a success since none of the GIGN received fatal injuries. French Prime ... The remaining passengers and crew survived the 20-minute gun battle.A Of the remaining passengers, 13 received minor injuries. ...
Eight would later die from their injuries. Twenty-one others survived their wounds. Captain Brindel ordered the starboard side ...
The three other physicians suffered minor injuries. Drew was trapped with serious wounds; his foot had become wedged beneath ... When reached by emergency technicians, he was in shock and barely alive due to severe leg injuries. Drew was taken to Alamance ... In truth, according to one of the passengers in Drew's car, John Ford, Drew's injuries were so severe that virtually nothing ...
... multiple severe injuries, unconscious; loss of arm or leg (or part); other chest injury, not bruising; deep penetrating wound; ... severe head injury, unconscious; severe chest injury, any difficulty breathing; internal injuries; ... injuries to casualties who die 30 or more days after the accident from injuries sustained in that accident. Barclays Cycle Hire ... Fatality and serious injury figures from Transport for London. Transport for London uses the Department for Transport's ...
"Young reporter dies from bomb injuries, media hounded throughout country". Reporters Without Borders. 21 June 2011. Retrieved ... Pakistan Press Foundation (21 June 2011). "Injured Journalist Dies of Blast Wounds". International Freedom of Expression ...
General injuries}}. Medicine. General wounds and injuries (T08-T35, 870-949). Medical condition templates. Footer. ... Nonmusculoskeletal injuries of head and neck}}. Medicine. Nonmusculoskeletal injuries of head (head injury) and neck (S00-S19, ... Nonmusculoskeletal injuries of abdomen and pelvis}}. Medicine. Nonmusculoskeletal injuries of abdomen and pelvis (S30-S39, 863- ... Injury : Fractures and cartilage injuries (Sx2, 800-829). Medical condition templates. Footer. ...
One occupier dead, one wounded. Death(s). Robert LaVoy Finicum[24]. Injuries. Ryan Bundy[23]. ... A bullet penetrates the roof of the truck, with shrapnel wounding Ryan Bundy in the shoulder. Finicum then quickly exits his ... One militant was killed while resisting arrest and one militant was wounded before being arrested. ... inflicting the minor shrapnel wound on Ryan Bundy.[138] OSP officers and FBI agents armed with rifles positioned themselves to ...
Any injury to human vocal folds elicits a wound healing process characterized by disorganized collagen deposition and, ... Wound healing[edit]. Wound healing is a natural regeneration process of dermal and epidermal tissue involving a sequence of ... Consequently, regenerative-type wound healing turns to be the formation of scar.[44][47] Scarring may lead to the deformity of ... This result was consistent with their previous study about the function of IL-1 and PGE-2 in wound healing.[48][49] ...
He dies from gunshot wounds. Some players argued against the death of the character Morpheus as the Matrix now provides an " ... This feature could save a redpill's life with no fatal injuries. It was later revealed that the Assassin's bullets had ... being the basis of function for The Apothecary character and the subject of The Oracle's plan to wound the Oligarchy. Rumors ...
... killing at least 20 people and wounding 84. 2 April - Five Cameroonian soldiers were killed and three others wounded in an ... The injuries came as a result of one of the suicide bomber's vest exploding. 8 July - At least 9 people were killed and "dozens ... Another one was wounded. 15 January - Four people were killed in Mayo-Tsanaga, a region of the Far North of Cameroon, during an ... Two were wounded. 4 June - At least 32 people were killed and 67 injured after hundreds of members of Boko Haram attacked the ...
Wounds and injuries take longer to heal. Wounds and injuries are more likely to leave permanent scars. Sleep trouble holds a ... Old age spells risk for injury from falls that might not cause injury to a younger person. Every year, about one-third of those ... Falls are the leading cause of injury and death for old people. Gait change. Some aspects of gait normally change with old age ... "Falls and Injury Statistics for Seniors and Elderly". Retrieved 2016-04-04. "Important Facts about Falls , ...
In 1471, Margaret's husband, Lord Stafford, died of wounds suffered at the Battle of Barnet, fighting for the Yorkists. At 28 ... Her son's birth may have done permanent physical injury to Margaret; despite two later marriages, she never had another child. ...
Hand and wrist injuries are reported to account for fifteen to twenty percent of emergency room injuries, and metacarpal ... Any open wounds are cleansed to avoid infection. For most fractures with less than 70 degrees of angulation, buddy taping and a ... Male intentional punch injuries are correlated predominantly with social deprivation, while female punch intentional injuries ... Approximately 3.7 male hand injuries, per 1000, per year, and 1.3 female hand injuries, per 1000, per year, have been reported ...
... wounds, broken bones and pain. Muscle atrophy results from a co-morbidity of several common diseases, including cancer, AIDS, ... when the patient has a primary injury such as an immobilized broken bone (set in a cast or immobilized in traction), for ...
... open wounds, cuts and abrasions.[41] Ebola may be spread through large droplets; however, this is believed to occur only when a ... The breakdown of endothelial cells leading to blood vessel injury can be attributed to EBOV glycoproteins. This damage occurs ...
Pregnancy category refers to an evaluation of a substance's risk of injury to a fetus if used by the mother during pregnancy.[ ... and its wound healing properties.[147] Topical and oral preparations of zinc are suggested treatments for acne; evidence to ... GBD 2015 Disease Injury Incidence Prevalence Collaborators (October 2016). "Global, regional, and national incidence, ... Hypertrophic scars remain within the original margins of the wound, whereas keloid scars can form scar tissue outside of these ...
Despite these injuries, however, the Wound Man is still depicted as standing defiantly alive.[4] This reaffirms the fact that ... The Wound Man illustrates various injuries that a person might receive through war, accident, or disease: cuts and bruises from ... The Wound Man continues to be referenced in popular culture: The constant invocation of the wound man in surgical treatises for ... The Wound Man is also referenced in season 1, episode 6 of NBC's Hannibal TV series in 2013, and again visually and by name in ...
Donkin JJ, Turner RJ, Hassan I, Vink R (2007). "Substance P in traumatic brain injury". Progress in Brain Research. 161: 97-109 ... and it was shown that substance P could promote wound healing of non-healing ulcers in humans.[38] SP and its induced cytokines ... which is a local inflammatory response to certain types of infection or injury.[28] Unfortunately, the reasons why NK1RAs have ... which is a local inflammatory response to certain types of infection or injury.[28] ...
Earnhardt dies instantly of head injuries, *^ Transcript of NASCAR's report on Earnhardt crash, August 21, 2001; USA ... As the laps wound down, Waltrip and Earnhardt, Jr. were running in first and second place, with Earnhardt Sr. behind them, ... After both cars came to a stop on the infield, Schrader climbed out of his car with minor injuries and went to check on ... "Earnhardt dies instantly of head injuries". ESPN Classic. November 19, 2003. Retrieved February 18, 2020.. .mw-parser-output ...
Not including non-combat deaths/injuries or non-critical wounds, Ottoman battle casualties were as follows:[45] ... Unknown followers and officers and 15 other ranks wounded. *^ Allen, W. E. D.; Muratoff, Paul (1999). Caucasian Battlefields: A ... If this average also held true in the Caucasus, total wounded would number 284,000.[46] Altogether, total Ottoman losses would ... The cost for the 2nd Army was 30,000 killed and wounded. The Russians strengthened their lines. They were strong enough to ...
The most common injuries are lips and gingivae. For lips, important to rule out presence of foreign objects in wounds and ... In preschool children, oral injuries make up as much as 17% of all bodily injuries. The incidence of traumatic dental injuries ... "Guidelines for the Management of Traumatic Dental Injuries: 3. Injuries in the Primary Dentition". Pediatric Dentistry. 39 (6 ... effectiveness of prevention of dental injuries is not complete, and injuries can still occur even when mouthguards are used as ...
He suffered severe facial injuries in a crash landing on Bintan Island in 1942, and whilst being evacuated; his ship was ... which left on 23 February and treated Gorton's wounds.[23] When the ship arrived in Fremantle, on 3 March, one of Gorton's arm ... During late 1944 Gorton went to Heidelberg Hospital for surgery which could not fully repair his facial injuries; he was left ... wounds had become septic and needed extensive treatment. However, he was more concerned about the effect that the sight of his ...
... the two signature injuries are posttraumatic stress disorder (PTSD) and traumatic brain injury (TBI). These two signature ... Rorke MA (1996). "Music and the Wounded of World War II". Journal of Music Therapy. 33 (3): 189-207. doi:10.1093/jmt/33.3.189. ... For instance, during a music therapy session, a man begins to play a song to a wounded Airmen. The Airmen says " [music] allows ... Neurological impairments following a brain injury can be in the form of apraxia - loss to perform purposeful movements, ...
"Injury. 41 (4): 329-334. doi:10.1016/j.injury.2009.08.007.. *^ Ringleb, Stacie I.; Dhakal, Ajaya; Anderson, Claude D.; Bawab, ... Many different knee injuries can happen. Three percent of knee injuries are acute traumatic patellar dislocations.[25] Because ... as injury to these structures may occur during the injury or during the reduction process.[3] Subsequent imaging studies are ... Wound healing. *Acute lung injury. *Crush syndrome *Rhabdomyolysis. *Compartment syndrome. *Contracture *Volkmann's contracture ...
Mule trains aided in the evacuation of wounded to some extent, but casualties were often carried for hours down the steep ... with few injuries and no loss of life. They also conducted parachute training jumps out of Al Asad Airbase. ... 2 paratroopers from 1-504 were killed, with several others wounded. They re-deployed to Fort Bragg in November 2014. ... with 23 killed and 202 wounded; eighteen enlisted men remained in Company B, and thirty-eight men and three officers in Company ...
InjuriesEdit. Re-educating wounded. Blind French soldiers learning to make baskets, World War I. ... Eye injuries, most often occurring in people under 30, are the leading cause of monocular blindness (vision loss in one eye) ... Injuries and cataracts affect the eye itself, while abnormalities such as optic nerve hypoplasia affect the nerve bundle that ... Cortical blindness results from injuries to the occipital lobe of the brain that prevent the brain from correctly receiving or ...
A British Transport Police officer was stabbed and suffered serious injuries to his head, face and neck.[57] An off-duty ... receiving multiple stab wounds and temporarily losing sight in his right eye as a consequence.[29] ... An unidentified bystander received an accidental gunshot wound as a result of the police gunfire, which was "not critical".[60] ... Two other Metropolitan Police officers received head and arm injuries.[59] ...
He soon turned to a life of crime (mostly train robberies) and died of gunshot wounds and tetanus in the Fresno jail in 1893 ... He accused the company of not providing him with medical care while he was recuperating from his on-the-job injury and then not ... Ricketts subsequently succumbed to his injuries three days later in the hospital.[13] ...
Diet Drug Orlistat Linked to Kidney, Pancreas Injuries. Medscape. Medscape News. [2011-04-26]. (原始内容存档于2012-05-10).. ... Ostomy Wound Manage. 2006-06, 52 (6): 34-6, 38, 40 passim. PMID 16799182.. ...
102 officers and 5,000 men dead and wounded or died of sickness[5]. 55 officers and 3,000 men dead, wounded, or died of ... who after his recovery from a severe head injury in the house of Kolberg senator Westphal was ordered to patrol the areas west ... of the civilian population of Kolberg, 27 died and 42 were wounded, primarily during the two final days.[53] ... Höpfner says that the Prussian archives reports list a total of 7,000 to 8,000 dead and wounded, 1,000 of whom were killed and ...
... goddess of curing sickness and healing wounds Aegle, goddess of the healthy glow Artemis, goddess of the hunt, wild animals, ... recuperation from illness or injury Vaidyanatha - Shiva as healer of all Ashvins, twin doctors of the gods and gods of ...
Although two others in the car were wounded, MacMichael escaped serious injury.[44] The authorities subsequently imposed a ... December 10 - A British soldier was killed and another wounded in Haifa.[135] Two Arabs wounded in an Irgun bombing in Haifa ... Two British policemen were killed, and three British soldiers were wounded. Two Irgun fighters were killed, four wounded, and ... The British reported 65 soldiers and 16 policemen wounded, while the Jews had 8 dead and 75 wounded.[112] ...
The flow between the Point of Injury and Hospital is required to be uninterrupted if a successful goal is to be met. ... Any and all casualties are transferred to the ORCA stage, given initial wound assessments, put into an initial medical state ( ... The process of simulation begins with the Point of Injury and leads into Casualty Collection Points, Ground Medical Evacuations ... Without proper combat engagement, realistic casualties and injuries cannot be simulated and cannot be transferred into the ...
I believed I had been fatally stabbed."[189] Following the attack, Harrison was hospitalised with more than 40 stab wounds, and ... puncturing a lung and causing head injuries before Olivia Harrison incapacitated the assailant by striking him repeatedly with ...
The death certificate also notes that she received five gunshot wounds to the body. The coroner denied The Courier-Journal's ... In October 2020, Mattingly's lawyer announced that he was filing a countersuit against Walker for his injury.[105] He alleged ... Mattingly was one of three officers who took part in the raid that killed Taylor, and the officer allegedly wounded by Walker. ... The police filed an incident report that claimed that Taylor had no injuries and that no forced entry occurred. The police ...
Ten times more soldiers died from illnesses such as typhus, typhoid, cholera and dysentery than from battle wounds. With ... She later transferred to a mule cart and was reported to have escaped serious injury when the cart was toppled in an accident. ... in which she organised care for wounded soldiers.[3] She gave nursing a favourable reputation and became an icon of Victorian ... Her team found that poor care for wounded soldiers was being delivered by overworked medical staff in the face of official ...
He gave water to both friends and foes who were wounded on the battlefield. Some of the enemy began to fight again and some ... Sculpture depicting the Jain concept of ahimsa (non-injury). The fundamental principles of Jainism revolve around the concept ... "I was giving water to the wounded because I saw your face in all of them," replied Bhai Kanhaiya. The Guru responded, "Then you ... should also give them ointment to heal their wounds. You were practicing what you were coached in the house of the Guru." ...
During and after the war, AMM staff took pictures of wounded soldiers showing effects of gunshot wounds as well as results of ... But new weapons and new environments bring new injuries, and epidemic disease remains a foe uniting all eras of combat. The ... "National Museum of Health and Medicine (NMHM): To Bind Up the Nation's Wounds". Retrieved 2019-06-19.. ... To Bind Up the Nation's Wounds: Medicine During the Civil War[35] shows Civil War medicine through the eyes of battlefield ...
Two of them were taken to hospital with stab wounds.[99]. *Aloha Airlines Flight 243 suffered a decompression which tore an 18- ... Several passengers saw the injury, but none saw how it happened. "When I first saw it, I thought he had just cut his head and ... Flight attendant Michelle Honda was thrown violently to the floor during the decompression but, despite her injuries, crawled ... More frequent situations may include a bleeding nose, illness, small injuries, intoxicated passengers, aggressive and anxiety ...
Navarra G, Pozza E, Occhionorelli S, Carcoforo P, Donini I (May 1997). "One-wound laparoscopic cholecystectomy". Br J Surg. 84 ... Potential complications include significant postoperative pain, injury to organs, bleeding, infection, incisional hernia, ...
Accidents see First Aid; Wounds and Injuries * Achilles Tendon Injuries see Heel Injuries and Disorders ... Thoracic Injuries see Chest Injuries and Disorders * Thumb Injuries see Finger Injuries and Disorders ... Tennis Elbow see Elbow Injuries and Disorders * ... Cranial Injuries see Head Injuries * Craniofacial Injuries see ...
Health Information on Wounds and Injuries: MedlinePlus Multiple Languages Collection ... Wounds and Injuries: MedlinePlus Health Topic - English Heridas y lesiones: Tema de salud de MedlinePlus - español (Spanish) ...
War Wounds and Injuries. Br Med J 1940; 2 doi: (Published 14 December 1940) Cite this ...
The wounding potential of a bullet is thus increased by tumbling or mushrooming upon impact. Further injury is often caused by ... Studies of body armour seek to prevent projectile penetration and minimize injury. ... Other articles where Gunshot wound is discussed: ballistics: ... wound ballistics. *. In ballistics. The wounding potential of a ... Further injury is often caused by fast-moving fragments of impacted bone. Studies of body armour seek to prevent projectile ...
... and other types are available to cover and protect your wound from dirt and water. ... Bandaging a wound like a burn, cut, or scrape requires different techniques depending on which part of the body was hurt. Ace ... American College of Surgeons: "Wound Home Skills Kit: Lacerations & Abrasions," "Wound Home Skills Kit: Surgical Wounds." ... First Aid: Bandaging Injuries and Wounds From Head to Toe. *Reviewed By: Charles Patrick Davis, MD, PhD ...
High-pressure injection injury: benign appearance belies potentially devastating consequences Anna T Ryan and Bruce R Johnstone ... Indigenous and non-Indigenous Australian children hospitalised for burn injuries: a population data linkage study. ...
... accidents and wounds: general and other. Includes any guidance, advice, NICE Pathways and quality standards. ... Injuries, accidents and wounds Injuries, accidents and wounds: general and other All NICE products on injuries, accidents and ... wounds: general and other. Includes any guidance, advice, NICE Pathways and quality standards. ...
Invisible Wounds: Closing the Gaps to More Effectively Address These Injuries. Photo by Mie Ahmt/Getty Images ... and depression and traumatic brain injury-conditions that have been labeled the "invisible wounds of war." When I started this ... Their injuries are real and are treatable. These men and women should receive the best care available, whether they access it ... At present, too few of the veterans who experience the invisible wounds of war get the help they need and even fewer get the ...
The spotlight on brain injuries suffered by American troops in Iraq this month is an example Americas episodic attention to ... this type of war wound, even though it has affected hundreds of thousands over the past two decades. ... Brain injuries in Iraq focus attention on invisible war wounds. Health Jan 30, 2020 2:03 PM EST WASHINGTON (AP) - The spotlight ... Unlike physical wounds, such as burns or the loss of limbs, traumatic brain injuries arent obvious and can take time to ...
... suffered by American troops in Iraq this month is an example of Americas episodic attention to this invisible war wound, which ... Unlike physical wounds, such as burns or the loss of limbs, traumatic brain injuries arent obvious and can take time to ... Brain injuries in Iraq put attention on invisible war wounds. Robert Burns ... The injuries have often been dismissed in part because the problem is not fully understood, although the Pentagon began ...
Wounds and injuries. Filed under: Eye -- Wounds and injuries*. Ophthalmic Care of the Combat Casualty. (from the Textbooks of ... Browsing subject area: Eye -- Wounds and injuries (Include extended shelves). You can also browse an alphabetical list from ... Eye -- Wounds and injuries. See also whats at your library, or elsewhere. ...
Understand the impact of pressure ulcers and pressure injuries on your practice and learn how to select a wound care dressing ... Wound care dressings: an important part of pressure ulcer/pressure injury prevention programs. As part of a comprehensive ... Ostomy Wound Management, 54(2).. ⁶World Union of Wound Healing Societies (WUWHS) Consensus Document. Role of dressings in ... Request a free pressure ulcer/injury staging card and wound measuring guide. ...
Doctors say they were confronted with the kinds of IED injuries that U.S. troops have gotten in Iraq and Afghanistan. ... "These were very disabling injuries in that the blast caused a lot of soft tissue injury. But also the shrapnel just rips ... Boston Doctors Compare Marathon Bomb Injuries To War Wounds. 04:24. ... And like those wounded troops, doctors say, many of those injured in the blasts Monday will require a lot of rehabilitation - ...
Equine Wound Care. Download this free guide to learn about the five different types of wounds and basic equine wound care. ... Minimizing Wound Complications. March 19, 2014. Wound care is one of those many horse issues where there are as many opinions ... Managing Penetrating Injuries in the Field February 17, 2013. Penetrating injuries can have serious consequences for horses, ... From Sterilization to Stitches: Handling Horse Wounds. May 18, 2017. Veterinarians weigh in on the dos and donts of wound ...
VioVet, the UKs leading online supplier of pet foods, pet medication, pet accessories and equine products, all at superb value.
Psychological and Cognitive Injuries, Their Consequences, and Services to Assist Recovery (Tanielian and Jaycox [Eds.], MG-720- ... Summarizes key findings and recommendations from Invisible Wounds of War: ... Invisible Wounds of War: Psychological and Cognitive Injuries, Their Consequences, and Services to Assist Recovery. Mar 26, ... Invisible Wounds of War: Summary of Key Findings on Psychological and Cognitive Injuries. Jun 11, 2008 ...
Wound irrigation to remove debris and lessen bacterial contamination is an essential component of open fracture care. However, ... Wound irrigation to remove debris and lessen bacterial contamination is an essential component of open fracture care. However, ... High-pressure flow has been shown to remove more bacteria and debris and to lower the rate of wound infection compared with low ... Antiseptic additives can kill bacteria in the wound, but host-tissue toxicities limit their use. Animal and clinical studies of ...
... to goats occur in many different ways. The producer must learn what he can handle himself and what ...
... linebacker Aldon Smith was stabbed at a house party early Saturday morning and is believed to have suffered minor injuries. ... We) are aware that Aldon Smith incurred minor injuries during an incident last night," the 49ers said in a statement. "We are ... SAN FRANCISCO -- The San Francisco 49ers say linebacker Aldon Smith suffered minor injuries during an incident Friday night in ... The Bee reported that all three were taken to the hospital with what were believed to be non-life-threatening injuries. ...
... according to the latest annual survey sponsored by the Wounded Warrior Project. ... More than 75 percent of wounded veterans are dealing with post-traumatic stress disorder, ... Traumatic Brain Injury (TBI) Wounded Warriors © Copyright 2018 All rights reserved. This material may not be ... Given the number of wounded vets reporting they could not get the mental health care they sought, the Wounded Warrior Project ...
LORD CLIVE DIES OF WOUNDS; Heir of Earl of Powis Succumbs to Battle Injuries.. OCT. 14, 1916. ... Archives,LORD CLIVE DIES OF WOUNDS; Heir of Earl of Powis Succumbs to Battle Injuries.. ... LORD CLIVE DIES OF WOUNDS; Heir of Earl of Powis Succumbs to Battle Injuries. Order Reprints, Todays Paper,Subscribe ...
Injuries to the skull 3 - 6. 3. Small penetrating wound on the top of the skull. * ... 5 and 6. Two similar but smaller wounds on the top rear of the skull.. ...
Unlike a physical injury that is visible, a moral injury remains invisible, making the suffering of the wounded hidden. ... Moral Injury of War: The Invisible Wound of Empire. A review of Hoopers War by Peter Van Buren ... "Well-meaning people would say, open the wound, let it out. The problem was those wounds had never closed in the first place. ... Moral injury is a ritual of war, a process of initiating a young man into a warrior. The invasion begins inside the hearts and ...
Injuries and violence are the third leading cause of death in the WHO European Region and pose a threat to economic and social ... European report on child injury prevention  Sethi, D; Towner, E; Vincenten, J; Segui-Gomez, M; Racioppi, F; (‎World Health ... Injuries are a leading cause of death and disability in children. This report presents evidence on how they can be prevented, ... Road traffic injuries in the WHO European Region represent a major public health problem. About 127 thousand people are killed ...
Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.. ...
... ... Browsing Faculty Research and Publications by Subject "Brain -- Wounds and injuries -- Research". Login ... Perinatal experience alters brain development and functional recovery after cerebral injury in rats  ...
... diabetic wounds, and negative pressure wound therapy. The first part exclusively deals with wounds from pressu ... This book introduces readers to the latest developments regarding pressure injury wounds, ... This book introduces readers to the latest developments regarding pressure injury wounds, diabetic wounds, and negative ... Negative-Pressure Wound Therapy as Prophylaxis for Surgical Site Infection in Perineal Wounds ...
... service members in Iraq and Afghanistan with an invisible wound: traumatic brain injury. ... Improvised explosive devices and associated blast injuries have left over 350,000 U.S. ... Head Injury, Hospital, Laboratory, Psychology, Research, Running, Seniors, T-Cell, Traumatic Brain Injury, Wound ... Aerobic exercise could help wounded warriors recover from mild traumatic brain injury. *Download PDF Copy ...
PPARs are such factors and are activated by lipid mediators produced after wounding. Here we highlight advances in our ... Tissue damage resulting from chemical, mechanical, and biological injury, or from interrupted blood flow and reperfusion, is ... program is largely based on rapid and specific changes in gene expression controlled by transcription factors that sense injury ... PPAR action during tissue repair and discuss the potential for these nuclear receptors as therapeutic targets for tissue injury ...
  • Survivors often suffered not just grievous physical wounds but also concussions that, along with psychological trauma, became known as the invisible wounds of war. (
  • Urinary cell cycle arrest proteins urinary tissue inhibitor of metalloprotease 2 and insulin-like growth factor binding protein 7 predict acute kidney injury after severe trauma: A prospective observational study. (
  • A few of these common presentations include burns, lacerations, trauma to the hand, and wounds, some of which do not require an evaluation by a specialist and can be managed outpatient by primary care clinicians. (
  • Associated trauma from falls and blasts resulting in spinal fractures and head injuries can occur. (
  • Introduction Among the factors related to survival among individuals with gun shot wounds (GSW) is distance to trauma care. (
  • Similarly, in a model of internal trauma and repair (murine air pouch model), endogenously produced adenosine released into areas of internal tissue injury stimulates angiogenesis because there was a marked reduction in blood vessels in the walls of healing air pouches of A(2A) receptor knockout mice compared to their wild-type controls. (
  • 4,8,9 Wound care specialists must be educated on phytophotodermatitis, which unfortunately has been misdiagnosed as nonaccidental trauma and can provoke a potentially embarrassing situation to the unsuspecting parent or adult caregiver who cannot recall any reasons precipitating such injuries. (
  • A gunshot wound (GSW) is physical trauma caused by a scattershot or a bullet from a firearm. (
  • In this article, which focuses on humans, wound healing is depicted in a discrete timeline of physical attributes (phases) constituting the post-trauma repairing process. (
  • Pub.L. 113-152 (text) (pdf)) is a bill that would amend the Public Health Service Act, with respect to trauma care and research programs, to include in the definition of "trauma" an injury resulting from extrinsic agents other than mechanical force, including those that are thermal, electrical, chemical, or radioactive. (
  • Major trauma is injury that can potentially lead to serious outcomes. (
  • The Improving Trauma Care Act of 2014 would amend the Public Health Service Act, with respect to trauma care and research programs, to include in the definition of "trauma" an injury resulting from extrinsic agents other than mechanical force, including those that are thermal, electrical, chemical, or radioactive. (
  • Under current law, the definition of trauma means an injury resulting from exposure to a mechanical force. (
  • The bill would expand the definition of trauma to also include an injury resulting from exposure to an extrinsic agent that is thermal, electrical, chemical, or radioactive. (
  • According to the organizations, the existing definition of "trauma" is too narrow and "excludes burn centers from participating in federal programs designed to support emergency medical care for those suffering from traumatic injuries or to compete for federal research support targeting trauma. (
  • Major trauma and the injury severity score--where should we set the bar? (
  • The first part exclusively deals with wounds from pressure ulcers, describing in detail their prevention, classification, and treatment. (
  • Deep tissue injury (DTI) is a phenomenon that was added into the classification of pressure ulcers by the National Pressure Ulcer Advisory Panel, 1 albeit with difficulty after a much prolonged debate. (
  • What are the indications for negative-pressure wound therapy (NPWT) in the treatment of pressure injuries (pressure ulcers)? (
  • Negative Pressure Wound Therapy is most commonly used with burns, flaps, ulcers and grafts, but it is contraindicated for several types of injuries, including wounds where there are exposed nerves, organs and vasculature. (
  • Due to the nature of the disease, diabetics may find that a minor injury with a small wound can rapidly progress into large ulcers and serious infections. (
  • In nearly all of these cases, the patients (whose injuries included ulcers, cat scratches and gunshot wounds) healed more rapidly with sugardine than with any alternative method of treatment. (
  • Previously, Stage I and suspected deep tissue injury were described as injured intact skin, while the other stages described open ulcers. (
  • the word injury encompasses both intact skin and open ulcers. (
  • Deep Tissue Injury (DTI) pressure ulcers have been considered as an additional pressure ulcer stage by the National Pressure Ulcer Advisory Panel (NPUAP) since 2007, yet there is still much confusion related to this pressure ulcer type. (
  • Most of this work has looked specifically at mental health issues such as posttraumatic stress disorder, and depression and traumatic brain injury-conditions that have been labeled the " invisible wounds of war . (
  • Research over the past decade has helped the nation understand the true size, scope and consequences of the invisible wounds of war. (
  • This monograph summarizes key findings and recommendations from a larger RAND document entitled Invisible Wounds of War: Psychological and Cognitive Injuries, Their Consequences, and Services to Assist Recovery (Tanielian and Jaycox [Eds. (
  • Our annual survey shows that this generation of injured veterans continue to struggle with the invisible wounds of war, including PTSD and TBI [traumatic brain injury] , and the challenges are not getting better with time," he said. (
  • The military medical communities have developed standard procedural sequences and principles that may assist and serve as references to the care of civilian gunshot wound patients. (
  • A wound is when there is loss of tissue from external causes such as a knife wound gunshot wound or bite wound. (
  • The immediate damaging effect of a gunshot wound is typically severe bleeding with the potential for hypovolemic shock, a condition characterized by inadequate delivery of oxygen to vital organs. (
  • A sudden blood gush may take effect immediately from a gunshot wound if a bullet directly damages larger blood vessels, especially arteries. (
  • When this happens, it is important to hold the sides of the wound together to aid healing. (
  • When a horse's healing process gets derailed, wounds can become chronic. (
  • A number of factors can enhance or derail wound healing. (
  • In: Oehmichen M, Kirchner H (eds) The wound healing process - forensic pathological aspects, Research in legal medicine, vol 13. (
  • Amon U, Gibbs BF, Wolff HH (1996) Mast cells: mediators and aspects of wound healing. (
  • Betz P (1996a) Collagen subtypes - markers for the healing of skin wounds. (
  • The body is great at healing minor injuries, and first-aid basics will help keep injuries from becoming serious or infected. (
  • Ghrelin accelerates wound healing in combined radiation and wound injury in mice. (
  • Impaired wound healing caused by radiation happens frequently in clinical practice, and the exact mechanisms remain partly unclear. (
  • The results demonstrated that ghrelin administration promoted cutaneous wound healing in irradiated mice, followed with reduced average wound closure time, increased spleen index (SI) and improved haematopoiesis. (
  • Western blotting indicated that ghrelin also increased the expression of vascular endothelial growth factor (VEGF) and transforming growth factor-β (TGF-β), both responsible for wound healing. (
  • Our results identify ghrelin as a novel peptide that could be used for radiation-induced impaired wound healing. (
  • Fibroblasts are the skin cells responsible for wound healing. (
  • Site for education, information, treatment of wound healing problems. (
  • Regulation of wound healing by granulocyte-macrophage colony-stimulating factor after vocal fold injury. (
  • Granulocyte-macrophage colony-stimulating factor (GM-CSF) facilitates epithelial wound healing, and recently, growth factor therapy has been applied to promote tissue repair. (
  • This study was undertaken to investigate the effect of GM-CSF on VF wound healing in vivo and in vitro. (
  • Why Isn't This Wound Healing? (
  • When should I seek treatment for a wound that isn't healing? (
  • As soon as you realize a wound isn't healing, you should seek treatment. (
  • Poor wound healing may occur in a number of situation but it is of particular concern to diabetics especially when it occurs on the legs. (
  • A non-healing wound is often the starting point and it is important for diabetics to understand how and why it occurs. (
  • What is a non-healing wound? (
  • As the name suggests, a non-healing wound is tissue injury that does not heal properly and within a period of time that would be considered normal. (
  • Many conditions can contribute to non-healing wounds and other factors like cigarette smoking, radiation exposure or corticosteroid use also play a role. (
  • A non-healing wound would refer to any wound that does not heal within 6 to 8 weeks despite proper wound care. (
  • It would be considered a chronic non-healing wound if it does not heal within 3 months. (
  • It may also be referred to as poor or impaired wound healing although non-healing wounds do not respond to measures utilized in traditional wound care management. (
  • Healing starts within a few minutes to several hours after an injury is sustained. (
  • With non-healing wounds, the wound remains 'open' for weeks or months and often there are relapses even after some healing occurs. (
  • How does wound healing occur? (
  • It is important to understand the physiology behind wound healing, Despite individual differences in healing capability and the size and depth of the wound, all wound healing undergoes the same systematic process. (
  • This allows for continuation of the next phase of wound healing. (
  • New skin grows over the wound and this phase of healing takes place over 2 to 3 weeks. (
  • The impairment of wound healing is worse in long standing, poorly managed diabetes. (
  • Adequate blood is necessary to carry cells and components necessary for a heightened immune response and healing of the wound. (
  • Overall the reduced blood supply means that the process of wound healing is impaired. (
  • However, the impairment of wound healing in diabetes is further complicated by the host of other effects that the disease has on the body. (
  • The immune system is weaker than normal and the formation of new blood vessels for wound healing is also impaired. (
  • These data uncover a novel role of pDCs in sensing nucleic acids in wounded skin and demonstrate their involvement in the acute inflammatory response and wound healing through their production of IFN-α/β. (
  • Wound healing is a complex process that is highly dependent on many skin cell types interacting in a defined order. (
  • With chronic wounds, this process is disrupted, and healing does not normally progress. (
  • It can also aid in the formation of an optimal treatment plan for when injuries do occur, which reduces the healing time and leads to better patient outcomes. (
  • The evolution of astrocyte reactivity, a wound healing response, was reduced in anti-Ly6G/Gr-1-treated mice, which also had less spared white matter and axonal preservation compared with isotype controls. (
  • These histological outcomes may be caused by alterations of growth factors and chemokines important in promoting wound healing. (
  • Although the spectrum of cells affected by anti-Ly6G/Gr-1 antibody treatment cannot be fully ascertained at this point, the correspondence of neutrophil depletion and worsened recovery suggests that neutrophils promote recovery after SCI through wound healing and protective events that limit lesion propagation. (
  • Similar to other injured tissues, an inflammatory response ensues after SCI, marking the beginning of wound healing and scarring events. (
  • Unexpectedly, the anti-Ly6G/Gr-1-treated mice displayed worsened neurological outcome after SCI and wound healing events were impeded. (
  • Several Technology Reports highlight products such as a negative pressure device that delivers a continuous subatmospheric pressure level to the wound bed to promote healing. (
  • Advanced dressings described in the reports can absorb fluid produced by the wound, cushion the surrounding area, and provide continuous cleansing to accelerate healing, reduce pain, and control swelling. (
  • Thanks to the Wound Healing Society, Advances in Wound Care is a peer-reviewed forum where the essence of latest advances in science contributed by world-experts meets practical solutions in wound care," says Editor-in-Chief Chandan K. Sen, PhD, Professor of Surgery and Director of the Comprehensive Wound Center at The Ohio State University Medical Center. (
  • Recent evidence indicates that topical application of adenosine A(2A) receptor agonists, unlike growth factors, increases the rate at which wounds close in normal animals and promotes wound healing in diabetic animals as well as growth factors, yet neither the specific adenosine receptor involved nor the mechanism(s) by which adenosine receptor occupancy promotes wound healing have been fully established. (
  • Thus, targeting the adenosine A(2A) receptor is a novel approach to promoting wound healing and angiogenesis in normal individuals and those suffering from chronic wounds. (
  • Avoid scrubbing the wounds vigorously, or using strong disinfectants or other chemicals, since this may harm tissue and delay wound healing. (
  • Wound healing was evaluated using an ear punch. (
  • OA, synovitis and wound healing were determined histologically, while bone changes were measured using microCT. (
  • Multivariate models were performed to elucidate the associations of dietary, metabolic and mechanical factors with OA and wound healing. (
  • Conclusions Our results indicate that with obesity, dietary FA content regulates wound healing and OA severity following joint injury, independent of body weight, supporting the need for further studies of dietary FA supplements as a potential therapeutic approach for OA. (
  • Wound healing refers to a living organism's replacement of destroyed or damaged tissue by newly produced tissue. (
  • The wound healing process is not only complex but also fragile, and it is susceptible to interruption or failure leading to the formation of non-healing chronic wounds. (
  • Factors that contribute to non-healing chronic wounds are diabetes, venous or arterial disease, infection, and metabolic deficiencies of old age. (
  • Wound care encourages and speeds wound healing via cleaning and protection from reinjury or infection. (
  • Timing is important to wound healing. (
  • Critically, the timing of wound re-epithelialization can decide the outcome of the healing. (
  • If the epithelization of a wounded area is fast, the healing will result in regeneration. (
  • A complementary model has recently been described where the many elements of wound healing are more clearly delineated. (
  • In this construct, the process of wound healing is divided into two major phases: the early phase and the cellular phase: The early phase, which begins immediately following skin injury, involves cascading molecular and cellular events leading to hemostasis and formation of an early, makeshift extracellular matrix that provides structural staging for cellular attachment and subsequent cellular proliferation. (
  • Some chronic wounds may not heal for years. (
  • Although there are different types of chronic wounds, those occurring from injury, such as skin tears or pressure injuries, are some of the most common. (
  • Unlike physical wounds, such as burns or the loss of limbs, traumatic brain injuries aren't obvious and can take time to diagnose. (
  • For generations, battlefield traumatic brain injuries were not understood and often dismissed," said Sen. Jeanne Shaheen, a New Hampshire Democrat. (
  • Check back here each week as a rotating cast of football watchers discusses the weekend's key plays, coaching decisions, and traumatic brain injuries. (
  • Do they use hyperbaric oxygen therapy at veterans hospitals for the vets that have traumatic brain injuries? (
  • If you get a facial injury that bleeds, clean the area with soap and water to decrease the risk of infection. (
  • Every time you remove the dressing, examine the wound for signs of infection. (
  • After weathering a natural disaster, take steps to reduce your horses' chances of infection or injury. (
  • High-pressure flow has been shown to remove more bacteria and debris and to lower the rate of wound infection compared with low-pressure irrigation, although recent in vitro and animal studies suggest that it may also damage bone. (
  • According to the FDA, 27 reports indicated infection from original open infected wounds or from retention of dressing pieces in the wound. (
  • Eventually, the moisture alone, or in conjunction with friction, will cause a break in the surface of the skin that allows pathogens to enter, making moisture-associated injuries very vulnerable to infection. (
  • Damage may include bleeding, broken bones, organ damage, infection of the wound, or loss of the ability to move part of the body. (
  • These were very disabling injuries in that the blast caused a lot of soft tissue injury. (
  • Here we highlight advances in our understanding of PPAR action during tissue repair and discuss the potential for these nuclear receptors as therapeutic targets for tissue injury. (
  • Deep Tissue Injury: What Is It Really? (
  • The Deep Tissue Injury pressure ulcer is one pressure ulcer type that can have a huge impact on your case because it tends to be incorrectly assessed, documented and/or treated. (
  • A deep tissue injury is a full-thickness pressure ulcer (injury down to deeper structures under the skin) although it initially appears as a superficial purple/maroon discoloration over a bony prominence or a blood-filled blister. (
  • The sooner the deep tissue injury is properly assessed the sooner the correct treatment plan can be implemented. (
  • The deep tissue injury evolves into a full thickness ulcer of a stage 3 or stage 4. (
  • However, the deep tissue injury should be added to the policy as a reportable event. (
  • Any area of purple discoloration should be documented as a deep tissue injury upon admission. (
  • As the deep tissue injury begins to open and deepen, the institution can look like the hero when properly treating a full-thickness pressure ulcer that had its beginnings before admission. (
  • Careful analysis of the medical record by a legal nurse consultant will determine when the deep tissue injury signs first appeared, and when the skin initially began to open and the ulcer worsened. (
  • Mary's attorney chose to file the lawsuit related to the negligently mounted dryer and did not file a claim against the hospital for the stage 3 pressure sore that evolved from the deep tissue injury. (
  • The velocity of the bullet is a more important determinant of tissue injury. (
  • Burns are injuries caused by fire, overheated materials, electricity, contact with chemical and radioactive substances, with exposure of this material to the body, can cause partial or total damage in the skin tissues and its annexes [6]. (
  • But in the patients we treat in our postoperative care clinics, the exit wound gives an indication of the unusual destruction of soft tissues and bones inside the wound. (
  • As injuries are very severe, the tissues are often difficult to recognize within the wound. (
  • After isolation and analysis of granulation tissues in combined radiation and wound injury (CRWI) mice treated with and without ghrelin, a phenomenon of increased DNA, hexosamine, nitrate and nitrite synthesis, elevated collagen content and enhanced neovascularization was observed after ghrelin treatment. (
  • Crush injuries can range from a minor injury on a small area of the body to a life-threatening injury that affects bones, tissues and major organs. (
  • Because crush injuries can affect any area of the body and can impact bones, muscles, organs and other tissues, this type of injury requires expert care from a variety of specialists. (
  • Extensive bleeding occurred in patients with vascular grafts (such as femoral and femoral-popliteal grafts), in sternal and groin wounds, in patients receiving anti-coagulant therapy, and during removal of dressings that adhered to or were imbedded in the tissues. (
  • Retention of foam dressing pieces and foam adhering to tissues or imbedded in the wound were noted in 32 injury reports. (
  • Injury refers to conditions that affects the tissues of our bodies in a detrimental fashion. (
  • Injuries need not cause skin breaks to cause damage tot he tissues. (
  • This book introduces readers to the latest developments regarding pressure injury wounds, diabetic wounds, and negative pressure wound therapy. (
  • In turn, chapters addressing diabetic wounds form the middle part of the book. (
  • One of the most interesting characteristics of AAM is its antibacterial and anti-inflammatory, anti-angiogenic, anti-fibrosis activity is an attractive approach for treating inflammatory disorders, wounds, and burns. (
  • In the face of injuries caused by burns, the patient meets with numerous sequels could result in physical and psychological limitations, changing the quality of life in daily activities and even social relationships [7]. (
  • The latest research - led by John O'Neill, from the Medical Research Council (MRC) Laboratory of Molecular Biology in Cambridge, England, in collaboration with NHS colleagues Ken Funn, from the Manchester Burns and Plastic Surgery Service, and John Blaikley, from the Centre for Respiratory Medicine and Allergy in Manchester - demonstrates for the first time how these clocks also influence how wounds heal. (
  • Burns, lacerations, and wounds are commonly encountered by primary care clinicians. (
  • Health care providers see presentations that may involve hand burns, trigger finger, hand lacerations, and wound complications. (
  • Burn depth is classified into 1 of 3 types (superficial, partial-thickness, and full-thickness burns) based on how deeply into the epidermis or dermis the injury might extend. (
  • Major burns can be devastating injuries. (
  • Substances such as honey, molasses and syrup have been used since ancient time on burns and wounds with a high degree of success. (
  • 5 Ortiz et al 7 demonstrated a decrease in bacterial counts on the wound surface and usefulness of the dressing in patients with burns. (
  • Meaning they no longer reimburse for pressure ulcer and pressure injury care unless the condition is present on admission. (
  • The anatomy of pressure ulcer/pressure injury risk. (
  • Request a free pressure ulcer/injury staging card and wound measuring guide. (
  • Wound care dressings: an important part of pressure ulcer/pressure injury prevention programs. (
  • An excellent choice for wound management and may help prevent skin damage as part of a comprehensive pressure ulcer/pressure injury prevention program. (
  • Learn proper preparation and placement techniques for pressure ulcer/pressure injury management. (
  • ³National Pressure Ulcer Advisory Panel, European Pressure Ulcer Advisory Panel and Pan Pacific Pressure Injury Alliance. (
  • National Pressure Ulcer Advisory Panel (NPUAP) announces a change in terminology from pressure ulcer to pressure injury and updates the stages of pressure injury. (
  • The use of sugardine treatment seems to accelerate granulation tissue and epithelial tissue production, thereby covering the wound, burn or ulcer with skin. (
  • The National Pressure Ulcer Advisory Panel (NPUAP) 1 has proposed a new term - pressure injury - as well as a new Pressure Injury Staging System to more accurately describe pressure phenomena. (
  • The injury can present as intact skin or an open ulcer and may be painful. (
  • Preliminary approval to search and replace ulcer with injury was provided in 1 day. (
  • Though the initial treatment of offloading of pressure to the area is the same, the stage 1 pressure ulcer could heal from the superficial injury relatively quickly without any untoward events. (
  • Betz P, Nerlich A, Wilske J, Tubel J, Wiest I, Penning R et al (1992a) The time-dependent rearrangement of the epithelial basement membrane in human skin wounds - immunohistochemical localization of collagen IV and VII. (
  • Epithelial tissue forms over the wound thereby sealing the wound from the environment. (
  • Concurrently, re-epithelialization of the epidermis occurs, in which epithelial cells proliferate and 'crawl' atop the wound bed, providing cover for the new tissue. (
  • Depletion of pDCs or inhibition of IFN-α/β receptor signaling significantly impaired the acute inflammatory cytokine response and delayed reepithelization of skin wounds. (
  • Advances in Wound Care is a bimonthly online journal that reports the latest scientific discoveries, translational research, and clinical developments in acute and chronic wound care. (
  • Twenty-eight full-thickness HAPIs occurred in fiscal year 2015 (FY15), and that trend continued into FY16 with 14 injuries on multiple units throughout a tertiary acute care center with 400 beds. (
  • Left over time and because of the slow evolution of the injury, 2 a clear demarcation line between viable and nonviable tissue will eventually occur, with the real extent of tissue loss visible only after surgical debridement. (
  • In addition to the basic understanding of the wounding patterns and potential extent of the damage caused by the ballistic characteristics of the missile, three principles need to be emphasized in the course of the treatment: timely debridement, delivery of antibiotics, and delayed closure of the wound. (
  • The debridement incision was extended to exclude the vascular injuries in the proximity of wound. (
  • The majority of these patients required surgical procedures for removal of the retained pieces, wound debridement, and treatment of wound dehiscence, as well as additional hospitalization and antibiotic therapy. (
  • Download this free guide to learn about the five different types of wounds and basic equine wound care. (
  • Veterinarians weigh in on the do's and don'ts of wound care, from discovery to recovery. (
  • Tweets from the Kester News Hour and sessions on wound management, neonatal care, rehabilitation, and more. (
  • Wound care is one of those many horse issues where there are as many opinions as there are horse owners. (
  • Wound irrigation to remove debris and lessen bacterial contamination is an essential component of open fracture care. (
  • Given the number of wounded vets reporting they could not get the mental health care they sought, the Wounded Warrior Project will begin a new program next year called Warrior Care Network. (
  • The group says it's a "first-of-its-kind medical care network" to connect wounded vets and their families with world-class, personalized mental health care. (
  • Shay describes how, when individuals are inflicted with this injury, their character begins to change, such that one's social and moral horizon shrinks and they lose capacity to care for others. (
  • Despite Karsh's relative luck, having successfully received medical care, life has been difficult for him and his family since the injury. (
  • Thought you might appreciate this item(s) I saw at Advances in Skin & Wound Care. (
  • As we move up to more serious injuries, again knowing what to do first is important, even if follow-up care must be done by a medic or hospital emergency room. (
  • Very serious injuries pose significant challenges for the surgeons, and will require months or even years of care. (
  • Experts in wound care, surgeons, pain management specialists, physical therapists and doctors from various specialties work together to create a care plan that addresses all your healthcare needs. (
  • To manage and treat skin tears properly, many aspects of patient care must be considered, including coexisting factors, nutrition, pain management, local wounds, and the optimal dressing. (
  • This includes a thorough initial assessment and diagnosis, timely resuscitation, knowledge of appropriate transfer criteria, early surgical care and wound coverage, rehabilitation, and continuous reassessment. (
  • Surgery's earliest known document describing the care of wounds, The Edwin Smith Surgical Papyrus , is dated about 1700 B.C. It describes the treatment of difficult wounds encountered on the battlefields of Egypt. (
  • Each issue provides a digest of the latest research findings, innovative wound care strategies, industry product pipeline, and developments in biomaterials and skin and tissue regeneration to optimize patient outcomes. (
  • To overcome veterans' reluctance to seek help for moral injury, Maguen incorporates mental health care into routine clinical visits. (
  • Pressure injuries (PIs) are costly to patients, health care institutions, and health care consumers. (
  • This descriptive study was conducted to review the impact of a multidisciplinary pressure injury prevention (PIP) team designed to provide a diverse perspective of patient care and to operate as a vehicle for institution-wide implementation of best practice and data dissemination for HAPI reduction. (
  • Previous work around PIP had focused on the creation of a best practice bundle, support surfaces, improving documentation, standardizing products, and building a team of certified wound care nurses. (
  • Limit your exposure to the bitter temperatures, and if you are concerned about an open wound resulting from a frostbite injury, please call Baptist Health Hardin Wound Care at 270.706.1010. (
  • She was admitted to the authors' burn center for wound care and pain control. (
  • Meticulous wound care and pain control for the treatment of these burn-like lesions are essential as is the need for the wound care specialist to be well versed on this topic to quickly identify the etiology of the injury, thereby avoiding misdiagnosing the patient with nonaccidental traumatic injuries. (
  • their unfortunate combination presents annually to health care wound specialists, dermatologists, and burn surgeons. (
  • Depending on each patient's needs, it can range from the simplest first aid to entire nursing specialties such as wound, ostomy, and continence nursing and burn center care. (
  • Betz P (1994) Histological and enzyme histochemical parameters for the age estimation of human skin wounds. (
  • Betz P (1995b) Immunohistochemical parameters for the age estimation of human skin wounds. (
  • pDCs were found to rapidly infiltrate both murine and human skin wounds and to transiently produce type I IFNs via TLR7- and TLR9-dependent recognition of nucleic acids. (
  • Add this abstract with record is bright: Examining literary and filmic representations of the open wound, this dissertation reveals injury to be an essential esthetic principle in the work of seven exemplary authors and two filmmakers from the French and German-language canons: Charles Baudelaire, Franz Kafka, Georges Bataille, Jean Genet, Hélène Cixous, Ingeborg Bachmann and Elfriede Jelinek, as well as Werner Schroeter and Michael Haneke. (
  • Two (2) Masters' prepared nurses - a certified wound ostomy continence (WOC) nurse and a clinical nurse specialist certified nurse (CNS-BC) - led the transition to implement the terminology change. (
  • There were multiple blunt force injuries of the head consisting of varying sized lacerations of the scalp and face, extensive skull fractures and intracranial injuries," according to her autopsy report. (
  • This mini-review offers a focuses on modern aspects of the biomaterials, growth factors, biocompatibility, and acellular matrix which are the basic elements for use in the tissue regeneration and replacement after an injury. (
  • Ghrelin was considered as a potent endogenous growth hormone-releasing peptide, and its role in enhancing wound repair and regeneration was firstly investigated in whole-body irradiated (γ-ray) mice in this study. (
  • lists information on injuries to elite athletes in Australia and provides descriptive pages about common sports injuries. (
  • provides advice and information on a variety of sports injuries. (
  • To determine which adenosine receptor is involved and whether adenosine receptor-mediated stimulation of angiogenesis plays a role in promotion of wound closure we compared the effect of topical application of the adenosine receptor agonist CGS-21680 (2-p-[2-carboxyethyl]phenethyl-amino-5'-N-ethylcarboxamido-adenosine) on wound closure and angiogenesis in adenosine A(2A) receptor knockout mice and their wild-type littermates. (
  • Thanks in large part to the mainstream media, today-36 years after the diagnosis was officially recognized and 15 years after 9/11-most Americans have heard of PTSD and traumatic brain injury. (
  • Rep. Bill Pascrell, Jr., a New Jersey Democrat and founder of the Congressional Brain Injury Task Force, faulted Trump for displaying "a clear lack of understanding of the devastating impacts of brain injury. (
  • Details of the U.S. injuries have not been made public, although the Pentagon said Tuesday that 31 of the 50 who were diagnosed with traumatic brain injury have recovered enough to return to duty. (
  • The injuries have often been dismissed in part because the problem is not fully understood, although the Pentagon began focusing on the problem in the early 1990s when it established a head injury program that grew into today's Defense and Veteran's Brain Injury Center. (
  • The Pentagon now says 50 service members have been diagnosed with traumatic brain injury caused by the Jan. 8 Iranian missile attack on an air base in Iraq where U.S. and coalition troops had taken cover in advance. (
  • Does brain injury link NFL players, wounded warriors? (
  • The suggestion made by the research is that a common thread binds those exposed to traumatic brain injury, whether it occurs on the football field or in the war theater. (
  • They have definitively shown that blasts and shaking of the head gives you the same pathology seen in sports concussions," said Dr. Jack Tsao, a Navy commander, neurologist and director of traumatic brain injury programs for the U.S. Navy Bureau of Medicine and Surgery . (
  • Concerns have been most recently centered on two combat-related injuries in particular: post-traumatic stress disorder and traumatic brain injury. (
  • The study discussed in this monograph focuses on post-traumatic stress disorder, major depression, and traumatic brain injury, not only because of current high-level policy interest but also because, unlike the physical wounds of war, these conditions are often invisible to the eye, remaining invisible to other servicemembers, family members, and society in general. (
  • The effect of traumatic brain injury is still poorly understood, leaving a large gap in knowledge related to how extensive the problem is or how to address it. (
  • Improvised explosive devices and associated blast injuries have left over 350,000 U.S. service members in Iraq and Afghanistan with an invisible wound: traumatic brain injury. (
  • Johnson is the principal investigator of a team of researchers on a two-year, $500,000 clinical trial to improve soldiers' quality of life supported by the Department of Defense to assess intensive cardiorespiratory exercise as a way to help wounded warriors recover from mild traumatic brain injury, or mTBI. (
  • By far, mTBI is the most common brain injury,' Johnson said. (
  • It really helped me realize the prevalence of mild traumatic brain injury in our war fighters. (
  • I am very excited about investigating the link between Alzheimer's disease and mild traumatic brain injury,' Johnson said. (
  • By early October, Chiarelli had become obsessed with the science of PTSD and traumatic brain injury. (
  • Contrary to what some believe, PTSD and traumatic brain injury are not phantom conditions exhibited by weak soldiers trying to get out of a deployment," he said. (
  • The Marine general was never particularly captivated by the science of PTSD or traumatic brain injury. (
  • To prevent traumatic brain injury, the doctors recommended new rules requiring troops who experienced a concussion to rest until a doctor cleared them for duty. (
  • The purpose of this study is to investigate the effectiveness of a manualized intervention (FITS) to families living with brain injury or spinal cord injury. (
  • It draws hundreds of Marine and Navy officials and dozens of clinicians charged with monitoring and treating troops suffering from post-traumatic stress, traumatic brain injury and related consequences of America's two wars. (
  • About 60,000 have suffered mild traumatic brain injury as a result of repeated exposure to explosions. (
  • offering brain injury support products. (
  • hyperbaric oxygen therapy for traumatic brain injury and post traumatic stress disorder). (
  • Can someone who experienced a mild tbi (traumatic brain injury) join the military? (
  • A person with knowledge of the situation told The Associated Press that Smith suffered stab wounds. (
  • A former Wilson Medical Center nurse who authorities say was killed by her husband nearly a year ago died as a result of a multiple blunt force injuries and stab wounds, her autopsy report states. (
  • And like those wounded troops, doctors say, many of those injured in the blasts Monday will require a lot of rehabilitation - both physical and mental. (
  • Evaluation of a Patient-Centered Fall-Prevention Tool Kit to Reduce Falls and Injuries: A Nonrandomized Controlled Trial. (
  • To address this trend, a multidisciplinary Pressure Injury Prevention (PIP) team was created. (
  • Amberg R (1996) Time-dependent cytokine expression in cutaneous wound repair. (
  • Phytophototoxic dermatitis is a strong phototoxic reaction to ultraviolet A (UV-A) radiation exposure after cutaneous contact with citrus fruit containing furocoumarins, leading to skin injury. (
  • The authors present a pediatric admission for burn-like injuries following prolonged cutaneous exposure to lemons while playing in the Arizona sunshine. (
  • Phytophotodermatitis is a nonimmunologic, dermatologic skin reaction mimicking a burn injury after cutaneous furocoumarin-containing plant contact followed by exposure to ultraviolet A (UV-A) radiation (320 nm-400 nm). (
  • Advances in Skin & Wound Care24(8):381-382, August 2011. (
  • ICD-9 code 862.3 for Injury to other specified intrathoracic organs with open wound into cavity is a medical classification as listed by WHO under the range -INTERNAL INJURY OF THORAX, ABDOMEN, AND PELVIS (860-869). (
  • Data from 118 burn patients showed that patients who suffered from a burn injury during nighttime hours took an average of 11 days longer to heal than patients who sustained similar wounds during the day. (
  • Negative Pressure Wound Therapy helps various types of open wounds heal by creating a negative pressure (vacuum) at a well-sealed wound site. (
  • Do you have a wound that seems to be taking forever to heal? (
  • For some veterans, this leaves emotional wounds that time refuses to heal. (
  • Some wounds may need to be sutured ("stitched") while others will be left open to heal. (
  • This repair program is largely based on rapid and specific changes in gene expression controlled by transcription factors that sense injury. (
  • PPARs are such factors and are activated by lipid mediators produced after wounding. (
  • The FDA has advised healthcare professionals to carefully consider patient risk factors before employing Negative Pressure Wound Therapy. (
  • Other risk factors include impaired mobility, falls or other accidental injuries, previous skin tears, cognitive deficit or dementia, and dependence in transfers. (
  • Risk factors for pressure injuries are the same as for skin tears. (
  • Platelet-derived growth factors are released into the wound that cause the migration and division of cells during the proliferative phase. (
  • The Ohio State Comprehensive Wound Center draws from the expertise and resources of a leading academic medical center, including advanced diagnostic techniques, hyperbaric oxygen therapy, minimally invasive vascular techniques and complex surgical reconstruction. (
  • Penetrating injuries can have serious consequences for horses, but vets are well-versed in handling them. (
  • What are some of the health risks and long-term consequences the wounded face? (
  • Injuries and wounds to goats occur in many different ways. (
  • Gunshot wounds have been an important source of injury for centuries and continue to occur. (
  • Moral injury can occur from what you witness or what you do," said Litz, a clinical psychologist, professor and counselor for the Department of Veterans Affairs. (
  • First, the risk of complications, especially infections, is very high for these types of injuries. (
  • The use of Negative Pressure Wound Therapy systems have been associated with deaths and serious complications, the U.S. Food & Drug Administration (FDA) warned yesterday. (
  • The wound can progress and complications mount and so do the litigation dollars. (
  • The initiation of clot formation also leads to the release of certain chemicals that attract inflammatory cells to the are of the injury. (
  • Spinal cord injury (SCI) induces a robust inflammatory response and the extravasation of leukocytes into the injured tissue. (
  • Spinal cord injury (SCI) elicits a complex cascade of events that further promote tissue destruction and ultimately results in poor clinical prognosis. (
  • Objective: To study the role of surgical exploration for vascular damage in penetrating war wounds, in the absence of diagnostic facilities. (
  • While surgical techniques have made giant strides during the past century, treatments of wounds themselves have made much slower progress. (
  • Granulation tissue starts to form at the site about 3 to 5 days after the injury. (
  • The granulation tissue contracts thereby pulling the ends of the wound closer together. (
  • It selectively removed debris from the wound by drawing out adherent fibrin and slough, while leaving healthy granulation tissue in place. (
  • There was no change in the rate of wound closure in the A(2A) receptor knockout mice compared to their wild-type littermates although granulation tissue formation was nonhomogeneous and there seemed to be greater inflammation at the base of the wound. (
  • In their mouths, all cats carry a large number of bacteria that are capable of causing tissue infections in bite wounds. (
  • More than 75 percent of wounded veterans are dealing with post-traumatic stress disorder , according to the latest annual survey sponsored by the Wounded Warrior Project. (
  • Unlike a better known casualty of war, post-traumatic stress disorder, or PTSD, moral injury is not yet a recognized psychiatric diagnosis, although the harm it inflicts is as bad if not worse. (
  • Antibiotic irrigation has been effective in experimental studies in some types of animal wounds, but human clinical data are unconvincing due to poor study design. (
  • This issue has been investigated particularly intensively in the detection of vital skin wounds and in the histopathological determination of skin wound age. (
  • However, critical voices highlight methodological problems such as the number of samples per skin wound, the undetermined effects caused by air and circulatory status, as well as environmental conditions (airflow, temperature, etc. (
  • Bai R, Wan L, Shi M (2008) The time-dependent expressions of IL-1β, COX-2, MCP-1 mRNA in skin wounds of rabbits. (
  • Berg S (1972) The timing of skin wounds. (
  • A wound is any break in the skin or deep tissue. (
  • Fibroblasts (red) invading a wound (blood clot, in blue) in mouse skin. (
  • The time of day you sustain a skin wound may influence how quickly it heals, according to a new study. (
  • A protein known as actin triggers fibroblasts to invade the area of a wound, where they produce restorative proteins like collagen to repair the damage and grow new skin. (
  • Wounds were produced at different times of the day, and the researchers noted the rate at which skin cells migrated to the vulnerable area. (
  • However, the findings were reversed in nocturnal mice, where skin cells moved more quickly and wounds healed faster when injuries occurred at night as the mice were most active. (
  • We show that pDCs also have the ability to sense host-derived nucleic acids released in common skin wounds. (
  • Cathelicidin peptides, which facilitate immune recognition of released nucleic acids by promoting their access to intracellular TLR compartments, were rapidly induced in skin wounds and were sufficient but not necessary to stimulate pDC activation and type I IFN production. (
  • These data uncover a new role of pDCs in sensing tissue damage and promoting wound repair at skin surfaces. (
  • However, whether skin injury is associated with pDC infiltration and activation to produce IFN-α/β is not known. (
  • In this paper, we found that skin injury induces an early and short-lived infiltration of pDCs into skin wounds. (
  • These pDCs were activated to produce IFN-α/β through TLR7 and TLR9, indicating that they recognize self-nucleic acids released by damaged cells in skin wounds. (
  • Moisture-associated skin injury , such as perineal dermatitis, diaper rash, and incontinence-associated dermatitis are caused by long-term, repetitive moisture that disrupts the normal pH of skin. (
  • Use skin cleanser to clean the wound. (
  • Skin tears are "wounds caused by shear, friction, and/or blunt force resulting in separation of skin layers. (
  • 2 The mechanical force created in these conditions will eventually lead to a wound, such as a skin tear. (
  • A type 1 tear has no skin loss, with a linear or flap tear that can be positioned to cover the wound bed. (
  • Type 2 involves partial skin loss, with a partial flap that cannot fully cover the wound. (
  • Also like skin tears, these injuries can be prevented when proper practices and technologies are in place that provide turning and repositioning strategies at an interval based on the patient's individual tissue tolerance, ideally every two hours or less. (
  • 2 Maintenance of skin integrity can be challenging because increased secretions, perspiration, drooling, short neck, voluminous skin folds, and immobility contribute to increased moisture- and friction-related injuries. (
  • Foam dressings such as Mepilex Lite or Mepilex Ag (Mölnlycke, Gothenburg, Sweden), moisture-wicking fabric, gauze, hydrofiber, and skin protectants are often used as the initial preventive product as well as treatment if injury develops. (
  • I would expect a wound to involve the skin being cut or grazed, whereas an injury might be a broken bone or an internal injury of some sort. (
  • In law, a wound breaks the skin. (
  • Mary's attorney received the case because of the head injury, but then also studied the rapid progression of skin breakdown, and wondered if he had a nursing malpractice case as well. (
  • When a cat bites, its sharp canine teeth easily puncture the skin, leaving small, but deep, wounds in the skin. (
  • A similar type of injury happens with cat scratches - the extremely sharp, curved nails penetrate deep into the skin, essentially injecting bacteria deep into the puncture wound. (
  • Most cat bite wounds are small punctures that drive pathogenic bacteria deep into the skin. (
  • Material and Methods: All wounded military personals having penetrating wounds with expected vascular injuries with positive soft signs were included in the study. (
  • Patients having abdominal, thoracic, intracranial vascular injuries, mangled limbs, and positive hard signs were excluded from the study. (
  • Results: Total 58 patients were received with expected vascular injuries. (
  • Hemorrhage in vascular injuries remains a leading cause of potentially preventable death on the modern battlefield. (
  • Warm ischemia time is an important deciding factor in the outcome of vascular injuries. (
  • Available at . (
  • SAN FRANCISCO -- The San Francisco 49ers say linebacker Aldon Smith suffered minor injuries during an incident Friday night in San Jose, Calif., and that he is recovering comfortably. (
  • We) are aware that Aldon Smith incurred minor injuries during an incident last night," the 49ers said in a statement. (
  • Officers fired at a fleeing pickup truck nearly struck the dog's handler and hit the dog, causing minor injuries, the police department said. (
  • Thoughts with regard to applying darwinian medicine (e.G., no nsaids) to minor injuries (sprains, contusions, and broken fings. (
  • Heir of Earl of Powis Succumbs to Battle Injuries. (
  • Steve Nardizzi, chief executive officer for the organization, said more than 23,000 veterans registered as members of Wounded Warrior Project completed the survey , making it the largest collection of data on the post-9/11 generation of wounded vets yet collected. (
  • Therapists both within and outside the Department of Veterans Affairs increasingly recognize moral injury as the reason so many returning vets are self-destructive and are not helped, or only partly helped, by established treatments for PTSD. (
  • A lot of vets won't seek help because what's haunting them are not heroic acts, or they were betrayed, or they can't live with themselves because they made a mistake," said Brett Litz, a mental health specialist with the VA Boston Healthcare System and a leading expert on moral injury. (
  • They say those suffering from moral injury contribute significantly to the horrific toll of suicide among returning vets - estimated as high as 18 to 22 a day in the United States, more than the number lost in combat. (
  • Shira Maguen, a research psychologist and clinician at the San Francisco VA Medical Center, who studies and treats vets suffering from moral injury, said, "We have a big focus on self-forgiveness. (
  • Animal and clinical studies of the use of antiseptics in contaminated wounds have yielded conflicting outcomes. (
  • There are few animal or clinical studies of musculoskeletal wounds. (
  • Often they lose consciousness for 30 seconds to six minutes -- but there's no penetrating injury,' said David K. Johnson, associate professor of clinical psychology at the University of Kansas. (
  • Diana Keel also suffered from "multiple sharp injuries" consisting of "large incised wounds" on the left side of her face and neck, the report indicates. (
  • We have to incise, upstream or downstream of the wound, to find the base of a nerve, a tendon, a blood vessel. (
  • A study being conducted at the University of Pittsburgh is helping our wounded warriors with facial injuries restore a more normal appearance. (
  • J. Peter Rubin, MD, a plastic surgeon and researcher conducting the study, says, "This is very important work because up to 26% of our wounded warriors have facial injuries. (
  • The book's last part, which focuses on negative pressure wound therapy, addresses all major aspects of this approach, reflecting the latest research. (
  • In a health alert posted on its Web site, the FDA said it will continue to monitor adverse events associated with Negative Pressure Wound Therapy systems, and will make available any new information that might affect their use. (
  • In the last two years, the FDA has received six death and 77 injury reports associated with Negative Pressure Wound Therapy systems. (
  • 3. Small penetrating wound on the top of the skull. (
  • Gunshot wounds can be particularly devastating compared to other penetrating injuries because the trajectory and fragmentation of bullets can be unpredictable after entry. (
  • A bullet with sufficient energy will have a cavitation effect in addition to the penetrating track injury. (
  • The study is open to both military personnel and civilians anywhere in the United States with visible injuries to the face or skull. (
  • Granulated white sugar and a generic ointment commonly called betadine, are mixed into a thick paste with the consistency of toothpaste or peanut butter and applied to the open wound. (
  • When treating the open wounds of the feet, the irritated soles and hooves were smeared with sugardine, and then bandaged for protection from unhygienic conditions. (
  • wound-open-abrasion-graze-scr. (
  • wound-open-abrasion-graze-scrape-injury-on-fo. (
  • ICD-9 code 854.13 for Intracranial injury of other and unspecified nature with open intracranial wound with moderate (1-24 hours) loss of consciousness is a medical classification as listed by WHO under the range -INTRACRANIAL INJURY, EXCLUDING THOSE WITH SKULL FRACTURE (850-854). (
  • Milley said all are categorized as "mild" injuries, but in some cases the troops will be monitored "for the rest of their lives. (
  • You may clean the wound with a mild salt solution, made by mixing 1 teaspoon (5 mls) of table salt in 2 cups (500 mls) of water. (
  • Non-fatal gunshot wounds frequently have mild to severe long-lasting effects, typically some form of major disfigurement such as amputation because of a severe bone fracture and may cause permanent disability. (
  • Speaking alongside Milley, Defense Secretary Mark Esper said the Pentagon is vigorously studying ways to prevent brain injuries on the battlefield and to improve diagnosis and treatment. (
  • Muscle contusion injuries: current treatment options. (
  • Due to burning injuries and impacts on public health due to the great economic consumption for treatment, constant research to improve the prognosis and the cost of treatment [9]. (
  • Duke was taken to a local veterinary for treatment for injuries to his leg and was sent home to recover. (
  • Nearly all those wounded US soldiers ended up in a US military hospital in Landstuhl, Germany for treatment. (
  • interactive injury treatment information. (
  • information resource on shoulder injuries and treatment. (
  • It has only been recently that scientific studies on various sugars used in wound treatment have backed up the folklore and ancient medical theories with scientific data (see the updated list of references that accompanies this article). (
  • Note added in Proof: Note the difference in glial cell reactivity when stab wound injury is performed through the skull (as recently published in März et al. (
  • Despite recent innovations and improvements in medicine, the three principles still stand, and may assist even surgeons with minimal experience in treating gunshot wounds to achieve reliable results. (