Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.Whooping Cough: A respiratory infection caused by BORDETELLA PERTUSSIS and characterized by paroxysmal coughing ending in a prolonged crowing intake of breath.Antitussive Agents: Agents that suppress cough. They act centrally on the medullary cough center. EXPECTORANTS, also used in the treatment of cough, act locally.Capsaicin: An alkylamide found in CAPSICUM that acts at TRPV CATION CHANNELS.Citric Acid: A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.Codeine: An opioid analgesic related to MORPHINE but with less potent analgesic properties and mild sedative effects. It also acts centrally to suppress cough.Reflex: An involuntary movement or exercise of function in a part, excited in response to a stimulus applied to the periphery and transmitted to the brain or spinal cord.Respiratory Sounds: Noises, normal and abnormal, heard on auscultation over any part of the RESPIRATORY TRACT.Expectorants: Agents that increase mucous excretion. Mucolytic agents, that is drugs that liquefy mucous secretions, are also included here.Bronchitis: Inflammation of the large airways in the lung including any part of the BRONCHI, from the PRIMARY BRONCHI to the TERTIARY BRONCHI.Bordetella pertussis: A species of gram-negative, aerobic bacteria that is the causative agent of WHOOPING COUGH. Its cells are minute coccobacilli that are surrounded by a slime sheath.Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)Nasal Decongestants: Drugs designed to treat inflammation of the nasal passages, generally the result of an infection (more often than not the common cold) or an allergy related condition, e.g., hay fever. The inflammation involves swelling of the mucous membrane that lines the nasal passages and results in inordinate mucus production. The primary class of nasal decongestants are vasoconstrictor agents. (From PharmAssist, The Family Guide to Health and Medicine, 1993)Common Cold: A catarrhal disorder of the upper respiratory tract, which may be viral or a mixed infection. It generally involves a runny nose, nasal congestion, and sneezing.Respiratory Tract DiseasesGuaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.Sputum: Material coughed up from the lungs and expectorated via the mouth. It contains MUCUS, cellular debris, and microorganisms. It may also contain blood or pus.Bronchial Provocation Tests: Tests involving inhalation of allergens (nebulized or in dust form), nebulized pharmacologically active solutions (e.g., histamine, methacholine), or control solutions, followed by assessment of respiratory function. These tests are used in the diagnosis of asthma.Respiratory Tract Infections: Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases.Respiration Disorders: Diseases of the respiratory system in general or unspecified or for a specific respiratory disease not available.Administration, Inhalation: The administration of drugs by the respiratory route. It includes insufflation into the respiratory tract.Adolescent Medicine: A branch of medicine pertaining to the diagnosis and treatment of diseases occurring during the period of ADOLESCENCE.Abortifacient Agents: Chemical substances that interrupt pregnancy after implantation.Pediatrics: A medical specialty concerned with maintaining health and providing medical care to children from birth to adolescence.Pertussis Toxin: One of the virulence factors produced by BORDETELLA PERTUSSIS. It is a multimeric protein composed of five subunits S1 - S5. S1 contains mono ADPribose transferase activity.Schools: Educational institutions.Salmonella enterica: A subgenus of Salmonella containing several medically important serotypes. The habitat for the majority of strains is warm-blooded animals.Health Services: Services for the diagnosis and treatment of disease and the maintenance of health.Health Services Accessibility: The degree to which individuals are inhibited or facilitated in their ability to gain entry to and to receive care and services from the health care system. Factors influencing this ability include geographic, architectural, transportational, and financial considerations, among others.Scapegoating: Process in which the mechanisms of projection or displacement are utilized in focusing feelings of aggression, hostility, frustration, etc., upon another individual or group; the amount of blame being unwarranted.Movement: The act, process, or result of passing from one place or position to another. It differs from LOCOMOTION in that locomotion is restricted to the passing of the whole body from one place to another, while movement encompasses both locomotion but also a change of the position of the whole body or any of its parts. Movement may be used with reference to humans, vertebrate and invertebrate animals, and microorganisms. Differentiate also from MOTOR ACTIVITY, movement associated with behavior.Disease Outbreaks: Sudden increase in the incidence of a disease. The concept includes EPIDEMICS and PANDEMICS.Guilt: Subjective feeling of having committed an error, offense or sin; unpleasant feeling of self-criticism. These result from acts, impulses, or thoughts contrary to one's personal conscience.Mandatory Testing: Testing or screening required by federal, state, or local law or other agencies for the diagnosis of specified conditions. It is usually limited to specific populations such as categories of health care providers, members of the military, and prisoners or to specific situations such as premarital examinations or donor screening.Pertussis Vaccine: A suspension of killed Bordetella pertussis organisms, used for immunization against pertussis (WHOOPING COUGH). It is generally used in a mixture with diphtheria and tetanus toxoids (DTP). There is an acellular pertussis vaccine prepared from the purified antigenic components of Bordetella pertussis, which causes fewer adverse reactions than whole-cell vaccine and, like the whole-cell vaccine, is generally used in a mixture with diphtheria and tetanus toxoids. (From Dorland, 28th ed)Health Personnel: Men and women working in the provision of health services, whether as individual practitioners or employees of health institutions and programs, whether or not professionally trained, and whether or not subject to public regulation. (From A Discursive Dictionary of Health Care, 1976)Health Status: The level of health of the individual, group, or population as subjectively assessed by the individual or by more objective measures.Delivery of Health Care: The concept concerned with all aspects of providing and distributing health services to a patient population.Public Health: Branch of medicine concerned with the prevention and control of disease and disability, and the promotion of physical and mental health of the population on the international, national, state, or municipal level.Attitude to Health: Public attitudes toward health, disease, and the medical care system.Attitude of Health Personnel: Attitudes of personnel toward their patients, other professionals, toward the medical care system, etc.Budgets: Detailed financial plans for carrying out specific activities for a certain period of time. They include proposed income and expenditures.Vaccination: Administration of vaccines to stimulate the host's immune response. This includes any preparation intended for active immunological prophylaxis.Decision Making: The process of making a selective intellectual judgment when presented with several complex alternatives consisting of several variables, and usually defining a course of action or an idea.Los AngelesMeasles: A highly contagious infectious disease caused by MORBILLIVIRUS, common among children but also seen in the nonimmune of any age, in which the virus enters the respiratory tract via droplet nuclei and multiplies in the epithelial cells, spreading throughout the MONONUCLEAR PHAGOCYTE SYSTEM.Measles Vaccine: A live attenuated virus vaccine of chick embryo origin, used for routine immunization of children and for immunization of adolescents and adults who have not had measles or been immunized with live measles vaccine and have no serum antibodies against measles. Children are usually immunized with measles-mumps-rubella combination vaccine. (From Dorland, 28th ed)Measles virus: The type species of MORBILLIVIRUS and the cause of the highly infectious human disease MEASLES, which affects mostly children.Lunch: The meal taken at midday.Congresses as Topic: Conferences, conventions or formal meetings usually attended by delegates representing a special field of interest.Sleep: A readily reversible suspension of sensorimotor interaction with the environment, usually associated with recumbency and immobility.Gastrointestinal Neoplasms: Tumors or cancer of the GASTROINTESTINAL TRACT, from the MOUTH to the ANAL CANAL.Interviews as Topic: Conversations with an individual or individuals held in order to obtain information about their background and other personal biographical data, their attitudes and opinions, etc. It includes school admission or job interviews.
Analysis with a combination of macrorestriction endonucleases reveals a high degree of polymorphism among Bordetella pertussis isolates in eastern France. (1/815)From 1990 to 1996, routine screening for whooping cough identified 399 patients with a calmodulin-dependent adenylate cyclase-positive test result and yielded 69 Bordetella pertussis isolates. None of the patients were fully vaccinated, and most were less than 6 months old. Analysis of total DNA by pulsed-field gel electrophoresis (PFGE) after XbaI, SpeI, or DraI macrorestriction yielded 19, 15, and 5 different patterns, respectively, whereas ribotyping failed to demonstrate any strain polymorphism. Discrimination among the isolates was improved by combining the PFGE profiles. Some patterns were more frequent, but the corresponding patients were not clearly epidemiologically related. The patterns for two strains obtained during a 3-month period from patients who were neighbors differed by the length of a single DNA fragment. These data strongly suggest that one type of isolate is widely spread throughout the world and is carried by individuals other than patients who develop a true illness. (+info)
Serum IgG antibody responses to pertussis toxin and filamentous hemagglutinin in nonvaccinated and vaccinated children and adults with pertussis. (2/815)Levels of IgG antibody to pertussis toxin (PT) and filamentous hemagglutinin (FHA) were measured in paired serum samples from 781 patients fulfilling at least one laboratory criterion for pertussis that was suggested by an ad hoc committee sponsored by the World Health Organization. The patients were participants or family members of participants in a double-blind efficacy trial of a monocomponent pertussis toxoid vaccine. Of 596 nonvaccinated children, 90% had significant (two-fold or more) rises in PT IgG and FHA IgG levels. Only 17 (32%) of 53 children previously vaccinated with three doses of pertussis toxoid had rises in PT IgG levels because they already had elevated PT IgG levels in their acute-phase serum samples. PT IgG and FHA IgG levels were significantly higher in acute-phase serum samples from 29 adults than in acute-phase serum samples from the nonvaccinated children. Nevertheless, significant rises in levels of PT IgG (79% of samples) and FHA IgG (90%) were demonstrated in adults. In conclusion, assay of PT IgG and FHA IgG in paired serum samples is highly sensitive for diagnosing pertussis in nonvaccinated individuals. Assay of PT IgG levels in paired sera is significantly less sensitive for diagnosis of pertussis for children vaccinated with pertussis toxoid. (+info)
Evidence of efficacy of the Lederle/Takeda acellular pertussis component diphtheria and tetanus toxoids and pertussis vaccine but not the Lederle whole-cell component diphtheria and tetanus toxoids and pertussis vaccine against Bordetella parapertussis infection. (3/815)A subanalysis of a recent cohort efficacy trial of a pertussis vaccine was performed to determine its efficacy against cough illnesses due to Bordetella parapertussis infections. Infants received four doses of either the Lederle/Takeda acellular pertussis component diphtheria and tetanus toxoids and pertussis (DTaP) vaccine or the Lederle whole-cell component diphtheria and tetanus toxoids and pertussis (DTP) vaccine at 3, 4.5, 6, and 15-18 months of age; controls received three doses of diphtheria and tetanus toxoids (DT) vaccine only. All subjects were prospectively followed for cough illnesses of > or = 7 days' duration; cases of B. parapertussis infection were confirmed by positive culture, household contact, or serology. Seventy-six cough illnesses due to B. parapertussis were identified; 24 occurred in 929 DTaP recipients, 37 in 937 DTP recipients, and 15 in 321 DT recipients, resulting in an efficacy of 50% for DTaP vaccine (95% CI [confidence interval], 5% to 74%) and 21% for DTP vaccine (95% CI, -45% to 56%). The data in the present analysis suggest that the Lederle/Takeda DTaP vaccine but not the Lederle whole-cell component DTP vaccine has efficacy against B. parapertussis infection. (+info)
Capture-recapture method for estimating misclassification errors: application to the measurement of vaccine efficacy in randomized controlled trials. (4/815)BACKGROUND: The measure of efficacy is optimally performed by randomized controlled trials. However, low specificity of the judgement criteria is known to bias toward lower estimation, while low sensitivity increases the required sample size. A common technique for ensuring good specificity without a drop in sensitivity is to use several diagnostic tests in parallel, with each of them being specific. This approach is similar to the more general situation of case-counting from multiple data sources, and this paper explores the application of the capture-recapture method for the analysis of the estimates of efficacy. METHOD: An illustration of this application is derived from a study on the efficacy of pertussis vaccines where the outcome was based on > or =21 days of cough confirmed by at least one of three criteria performed independently for each subject: bacteriology, serology, or epidemiological link. Log-linear methods were applied to these data considered as three sources of information. RESULTS: The best model considered the three simple effects and an interaction term between bacteriology and epidemiological linkage. Among the 801 children experiencing > or =21 days of cough, it was estimated that 93 cases were missed, leading to a corrected total of 413 confirmed cases. The relative vaccine efficacy estimated from the same model was 1.50 (95% confidence interval: 1.24-1.82), similar to the crude estimate of 1.59 and confirming better protection afforded by one of the two vaccines. CONCLUSION: This method allows supporting analysis to interpret primary estimates of vaccine efficacy. (+info)
Pertussis is increasing in unimmunized infants: is a change in policy needed? (5/815)The proportion and trend in absolute number of pertussis notifications in young infants has increased each year in England and Wales since the accelerated immunization schedule was introduced. We report five infants all less than 3 months of age admitted with life threatening pertussis infection to two paediatric intensive care units. Despite aggressive cardiorespiratory support measures, three of the infants died. Pertussis remains a significant cause of morbidity and mortality in unimmunized infants. In this age group presentation is likely to be atypical and infection more severe. Public health measures to prevent the disease could be strengthened. Chemoprophylaxis should be offered to susceptible contacts and booster vaccinations against pertussis considered. (+info)
Respiratory diseases among U.S. military personnel: countering emerging threats. (6/815)Emerging respiratory disease agents, increased antibiotic resistance, and the loss of effective vaccines threaten to increase the incidence of respiratory disease in military personnel. We examine six respiratory pathogens (adenoviruses, influenza viruses, Streptococcus pneumoniae, Streptococcus pyogenes, Mycoplasma pneumoniae, and Bordetella pertussis) and review the impact of the diseases they cause, past efforts to control these diseases in U.S. military personnel, as well as current treatment and surveillance strategies, limitations in diagnostic testing, and vaccine needs. (+info)
Bordetella holmesii-like organisms isolated from Massachusetts patients with pertussis-like symptoms. (7/815)We isolated Bordetella holmesii, generally associated with septicemia in patients with underlying conditions, from nasopharyngeal specimens of otherwise healthy young persons with a cough. The proportion of B. holmesii-positive specimens submitted to the Massachusetts State Laboratory Institute increased from 1995 to 1998. (+info)
Stochastic dynamics and a power law for measles variability. (8/815)Since the discovery of a power law scaling between the mean and variance of natural populations, this phenomenon has been observed for a variety of species. Here, we show that the same form of power law scaling also occurs in measles case reports in England and Wales. Remarkably this power law holds over four orders of magnitude. We consider how the natural experiment of vaccination affects the slope of the power law. By examining simple generic models, we are able to predict the effects of stochasticity and coupling and we propose a new phenomenon associated with the critical community size. (+info)
"Promoting Adult Pertussis Vaccination in the Workplace" by Jennifer Bainum, Karlen Beth Luthy et al.
Vaccines are an important disease prevention strategy among individuals of all age groups. Despite the success of vaccinations in preventing communicable diseases, adults, in particular, often have sub-optimal vaccination rates. Consequently, some vaccine-preventable diseases, such as pertussis, are still on the rise in the United States despite the availability of the Tdap vaccine. As most adults can be found in the workplace, occupational health and environmental health nurses (OHEHNs) are in a unique role to encourage employers to promote adequate Tdap vaccination among their employees. As specific resources regarding Tdap vaccination are lacking, the Pertussis Prevention Toolkit was developed to help OHEHNs promote Tdap vaccination in the workplace.
DTaP booster not cost effective unless pertussis incidence high | SpringerLink
Allergy reactions to vaccine ingredients
Pertussis infection has been suspected to be a potential causal factor in the development of atopic disease because of the effect of pertussis immunization on specific IgE antibodies. Although several studies found a positive association between pertussis infection and atopic disorders, this relationship has not yet been studied in a population stratified by vaccination status. To assess the association between pertussis infection and atopic disorders in pertussis-unvaccinated children and in pertussis-vaccinated children. Using data from a previously conducted study on the relationship between the diphtheria-tetanus-pertussis-(inactivated) poliomyelitis vaccination in the first year of life and atopic disorders, the study population of 1872 8-12 yr old was divided into children pertussis-unvaccinated and children pertussis-vaccinated in the first year of life. Within each group, the association between pertussis infection and atopic disorders (both as reported by the parents) was assessed. In ...
Epidemic curve of a pertussis outbreak, September 2010 | Open-i
L'Oréal works to drive awareness of skin cancer risk in skin of color - Drug Store News
The survey was conducted online in May 2012 by Harris Interactive on behalf of the Sounds of Pertussis Campaign, a joint initiative from Sanofi Pasteur and March of Dimes.. The results spotlight that most parents are skipping a critical preventive health step for themselves and their babies, and its not because they dont think its important. A large majority of parents with children ages 2 years and younger (83%) believe that vaccination is important for adults in contact with infants and young children to help protect against the spread of pertussis. Yet only 19% reported asking friends and family in close contact with their child to get an adult pertussis vaccination. Although 90% agreed that the health of family/friends/caregivers is an important consideration in order to keep their children healthy and safe, 45% estimated that fewer than half of the adults who come into close contact with their children had received an adult pertussis vaccination, and 26% werent sure if anyone had been ...
Pertussis Outbreak, Southeastern Minnesota, 2012 [Communiqué] - Insights
Pertussis Outbreak in California: What You Need To Know
Department of Health | Pertussis
Since 1993, pertussis has caused the greatest morbidity of any disease preventable by vaccines recommended for children on the National Immunisation Program (NIP) schedule. The highest numbers of pertussis notifications were seen in 2005, with many jurisdictions experiencing an epidemic in that year, followed by 1997 and 2001. Traditionally, hospitalisations in infants aged less than one year have exceeded notifications, indicating that notification rates tend to underestimate pertussis incidence.3,149 However, in the 2003-2005 period, there were more notifications than hospitalisations in this age group, which may be a reflection of the increased use of PCR to diagnose pertussis in children. In children, hospitalisations coded as whooping cough have been shown to have a high correlation with clinical pertussis.19 The high proportion (greater than 50%) of hospitalised cases aged less than one year is consistently observed each year and demonstrates the increased morbidity of pertussis in this ...
The City of Lubbock Health Depart. issues public health advisory - KCBD NewsChannel 11 Lubbock
LUBBOCK, TX (KCBD) - The City of Lubbock Health Department would like to notify citizens and clinicians of an increase in Pertussis cases this spring. There have been 22 reported cases in Lubbock County so far in 2010. There were 29 total reported cases of Pertussis in 2009.. Pertussis cases generally increase in the spring and fall months. Pertussis, which is also known as Whooping Cough, is spread by infected persons coughing or sneezing while in close contact with others, who then breathe in the Pertussis bacteria. Many infants who get pertussis are infected by older siblings or parents who might not even know they have the disease.. Pertussis can cause serious illness in children and adults. The disease starts like the common cold, with runny nose or congestion, sneezing, and sometimes mild cough or fever. The cough worsens, becoming severe after 1-2 weeks. Children with the disease cough violently and rapidly, over and over, until the air is gone from their lungs and theyre forced to ...
Pertussis case confirmed at Whitworth Elementary | Polk Couny Itemizer-Observer mobile site
DALLAS - A child at Whitworth Elementary School has been positively diagnosed with a case of pertussis, or whooping cough. The Dallas School District sent out letters of the confirmed case on Friday afternoon.. Pertussis is a highly contagious, serious bacterial infection, according to the informational letter sent by DSD. It is spread by coughing and sneezing.. "It starts with a mild cough and can be very similar to cold-like symptoms," said Katrina Rothenberger, public health administrator for Polk County Public Health.. If a cough persists longer than two weeks - or causes gagging or vomiting - that person should be tested for whooping cough, she said, especially if the patient is a child or infant.. "Our recommendation is to test patients with a cough of two weeks duration or a close contact with a confirmed case with acute cough," she said.. People who are up to date on DTap vaccinations - having received five vaccinations upon entering kindergarten - are considered protected against the ...
Pertussis cases confirmed in Prowers County - Lamar Ledger
eDrug Update - March 2017
The pertussis booster vaccine administered in adolescents and adults, known as Tdap vaccine, provides protection against three different diseases-tetanus, diphtheria, and pertussis. It should also be given to anyone in these age groups who will be in close contact with an infant younger than 12 months or close contact with a pregnant mother. The recommended time of vaccination for expectant mothers is from gestational weeks 27 through 36. Because the level of pertussis antibodies decreases over time, Tdap should be administered during every pregnancy so that the greatest number of protective antibodies can be transferred to each infant. Postpartum Tdap administration can only provide protection to the mother, and it could take about 2 weeks after administration for the mother to have protection against pertussis. Until the mother develops protection, she is at risk for contracting and spreading pertussis to her vulnerable infant. The vaccine should only be administered postpartum if a woman has ...
How to Stop Rising Numbers of Vaccine Exemptions - Vaccine Nation
In some states the rate of non-medical exemptions has risen above 5% and this has caused an increase in cases of preventable diseases in pockets of vaccinated children across the US. The result is that cases of viruses like measles, pronounced eradicated in the US back in 2000, have risen sharply over the past decade. In the case of measles, the number of cases has rocketed from 60 cases in 2001 to 222 cases in 2011.. Numerous other high profile outbreaks have been linked to these pockets of unvaccinated people, including the 2010 pertussis outbreak in California and the 2012 Washington pertussis outbreak. As a result legislators and policy makers have been trying to reduce the number of vaccine exemptions by making it more difficult for parents to obtain them. But the authors suggest that, of the three types of legislation policy makers have been experimenting with (Mandating vaccinations, philosophical versus religious exemptions, and challenging the sincerity of applicants) none have proved ...
Pertussis re-emergence in the post-vaccination era | BMC Infectious Diseases | Full Text
In a recent review Millier and colleagues identified 13 cost-effectiveness, cost-utility and economic impact models regarding the impact of adolescent booster, one-time adult booster, adult decennial boosters and/or cocoon strategy. Adolescent booster was found to be a cost-effective strategy compared with no booster vaccination in all the nine considered studies . As an example, Purdy et al. showed that immunizing adolescents aged 10-19 years would be the most economical strategy since it would prevent 0.7-1.8 million pertussis cases and save $0.6-1.6 billion over a decade in US . However, in another recent review including 16 studies using a dynamic model, adolescent vaccination was found to be cost effective, but not highly effective in protecting infants too young to be vaccinated . Similarly in another recent study, using an age-structured compartmental deterministic model, a single Tdap dose at age 11 years significantly would reduce the incidence of the disease within this age ...
NNii : Immunization Science
The break even costs for each of the strategies were $28.86 - 36.92. Immunization of adolescents 10-19 years of age would be expected to prevent 0.4-1.8 million cases among the adolescents, saving $1.3-1.6 billion. If caretakers of young infants were immunized, 160,000 801,000 pertussis cases among caretakers and 1,700 8,600 cases among infants 1 year of age or less might be prevented. Six to 32 infant deaths would be prevented, and $0.2 billion to $1.2 billion would be saved. Immunization of health care workers each decade would prevent 20,000 100,000 cases of pertussis and would save $30 million to $151 million. If all adults in the United States 18 years of age and older with COPD were immunized against pertussis each decade, 768,000 cases of pertussis might be prevented, and more than $1.3 billion could be saved. ...
A looming whooping cough epidemic - that
George Till, a state House representative and a physician, tried to change that last year by proposing a bill to eliminate the philosophical exemption to vaccines. Instead, Act 157, which became law on July 1, 2012 - when the current pertussis epidemic was already raging - turned into a complicated, compromise vaccine bill that preserved the philosophical exemption.. The protesters blared the discredited claim that vaccines cause autism. Till lives and practices near Burlington, Vt., and was elected to the House four years ago. In his re-election campaign, he spent $18.55 for dog bones. With dog treats in hand, this soft-spoken doctor went door to door and asked his neighbours to vote for him. Till, an OB-GYN and a Democrat, did not accept donations to his campaign from any group - he even sent back a cheque from Planned Parenthood.. Act 157 originated when a pediatrician neighbour of Tills came to him with a concern. In a local kindergarten class, 75% of students were not fully vaccinated. ...
Virulence of Pertactin-Negative Bordetella pertussis Isolates from Infants, France - Volume 19, Number 3-March 2013 - Emerging...
Bordetella pertussis isolates that do not express pertactin (PRN) are increasing in regions where acellular pertussis vaccines have been used for >7 years. We analyzed data from France and compared clinical symptoms among infants <6 months old infected by PRN-positive or PRN-negative isolates. No major clinical differences were found between the 2 groups.
Detection of anti-pertussis toxin IgG in oral fluids for use in diagnosis and surveillance of Bordetella pertussis infection in...
Bordetella pertussis infection is being increasingly recognized as a cause of prolonged, distressing cough (without whooping symptoms) in children and young adults. Diagnosis of infection in this population is important for treatment and surveillance purposes, and may also prove useful in reducing transmission to unvaccinated babies, for whom disease can be fatal. Serum IgG titres against pertussis toxin (PT) are routinely used as a marker of recent or persisting B. pertussis infection. However, collection of serum from young children is difficult, and compliance amongst these subjects to give samples is low. To circumvent these problems, an IgG-capture ELISA capable of detecting anti-PT IgG in oral fluid was devised. The assay was evaluated by comparison to a serum ELISA, using 187 matched serum and oral fluid samples from children (aged 5-16 years) with a history of prolonged coughing, whose serum anti-PT titre had already been determined (69 seropositive, 118 seronegative). The results showed that,
Rapid Increase in Pertactin-deficient Bordetella pertussis Isolates, Australia - Volume 20, Number 4-April 2014 - Emerging...
Acellular vaccines against Bordetella pertussis were introduced in Australia in 1997. By 2000, these vaccines had replaced whole-cell vaccines. During 2008-2012, a large outbreak of pertussis occurred. During this period, 30% (96/320) of B. pertussis isolates did not express the vaccine antigen pertactin (prn). Multiple mechanisms of prn inactivation were documented, including IS481 and IS1002 disruptions, a variation within a homopolymeric tract, and deletion of the prn gene. The mechanism of lack of expression of prn in 16 (17%) isolates could not be determined at the sequence level. These findings suggest that B. pertussis not expressing prn arose independently multiple times since 2008, rather than by expansion of a single prn-negative clone. All but 1 isolate had ptxA1, prn2, and ptxP3, the alleles representative of currently circulating strains in Australia. This pattern is consistent with continuing evolution of B. pertussis in response to vaccine selection pressure.
Pathology and pathogenesis of fatal Bordetella pertussis infection in infants | Read by QxMD
BACKGROUND: Each year, Bordetella pertussis infection causes an estimated 294,000 deaths worldwide, primarily among young, nonvaccinated children. Approximately 90% of all deaths due to pertussis in the Unites States occur in young infants. These children often develop intractable pulmonary hypertension; however, the pathophysiologic mechanism responsible for this complication has not been well characterized, and there have been no detailed descriptions of the pathology of this disease since the 1940s.. METHODS: Respiratory tissue samples obtained at autopsy from 15 infants aged ,or=4 months who had polymerase chain reaction- or culture-confirmed B. pertussis pneumonia were evaluated by multiple histochemical stains, immunohistochemical evaluation, and electron microscopic examination.. RESULTS: The pulmonary histopathologic examination of the samples revealed a descending infection dominated by necrotizing bronchiolitis, intra-alveolar hemorrhage, and fibrinous edema. All samples had marked ...
Bordetella Pertussis Infections in Vaccinated and Unvaccinated Adolescents and Adults, as Assessed in a National Prospective...
Background. Acellular pertussis (aP) booster immunizations have been recommended for adolescents and older persons to enhance long-term protection and to possibly reduce community transmission of infections.. Methods. This was a multicenter, randomized, double-blind vaccine trial in which one-half of the subjects received aP vaccine and one-half received hepatitis A vaccine (control subjects). All subjects were observed for almost 2 years for cough illnesses, and all underwent microbiologic and serologic studies for detection of pertussis infection. Immunoglobulin G (IgG) and immunoglobulin A (IgA) antibodies to pertussis toxin, filamentous hemagglutinin, pertactin, and fimbriae 2/3 were measured by enzyme-linked immunosorbent assay in serum samples obtained 1 and 12 months after immunization. Infection rates were determined with a variety of serologic criteria for control and vaccinated subjects. The incidence of prolonged cough illness was ascertained for subjects with and subjects without ...
Use of Diphtheria Toxoid-Tetanus Toxoid-Acellular Pertussis Vaccine as a Five-Dose Series
Swelling involving the entire thigh or upper arm has been reported after booster doses of different acellular pertussis vaccines. Swelling of the entire thigh was reported among recipients of a booster dose of JNIH-6 (a two-component acellular pertussis vaccine produced by Biken [Japan] and comparable to the acellular pertussis component contained in Tripedia). During a study performed in Sweden during the 1980s, children who had previously received two or three doses of Biken acellular pertussis vaccine at age 6--8 months received a booster dose deep subcutaneously of the same vaccine at age 2 years. Certain children experienced substantial local reactions, including swelling of the entire thigh (16), although administration of vaccine subcutaneously could have influenced reaction rates in that study. Occurrence of extensive swelling involving the entire thigh of vaccinated children was reported among DTaP recipients in an open-label safety study in Germany during April 1993--November 1994, in ...
Clinical findings in Bordetella pertussis infections : results of a prospective multicenter surveillance study - edoc
OBJECTIVE: To study the clinical presentation of culture-confirmed pertussis in children and their contacts with cough illnesses in an outpatient setting. METHODOLOGY: In conjunction with a large pertussis vaccine efficacy trial in Germany, a central laboratory to isolate Bordetella species from nasopharyngeal specimens was established in Erlangen in October 1990. Pediatricians in private practices in southern Germany, the Saar region, and Berlin were encouraged to obtain nasopharyngeal specimens and clinical characteristics from patients with cough illnesses ,/=7 days duration. Bordetella species were isolated by use of calcium alginate swabs, Regan-Lowe agar, and modified Stainer-Scholte broth. Clinical characteristics were determined by initial and follow-up questionnaires. RESULTS: From October 1990 to September 1996, 20 972 specimens were submitted, and B pertussis was isolated in 2592 instances (12.4%). Of the culture-proven cases, 50.7% were female, and the age range was 6 days to 41 ...
Number and Order of Whole Cell Pertussis Vaccines in Infancy and Disease Protection | JAMA | The JAMA Network
Less Effective Pertussis Vaccines Explains Increasing Whooping Cough - The Doctor's Channel
In the 1990s, the US replaced whole cell pertussis vaccines with acellular pertussis vaccines over safety concerns. A research letter to Journal of the American Medical Association reports that the switch might be responsible for a recent rising number of pertussis cases (whooping cough) in children. Compared with whole cell...
Increased number of pertussis cases
SPRINGFIELD, Ill. - As we enter flu season, and with reports of increased number of pertussis cases in some Illinois counties, Illinois Department of Public Health Director Dr. Damon T. Arnold is reminding people of the importance of vaccinations and preventive measures that should be used to avoid getting sick.. "Some northern Illinois counties are reporting an increased number of pertussis, or whooping cough, cases this year compared to 2007. This is a good reminder why vaccinations are so important," said Dr. Arnold. "Its also important to do simple things like cover your mouth with a tissue if you cough or sneeze. If you dont have a tissue, try to cough or sneeze into your sleeve. Thoroughly washing your hands with soap and warm water will also prevent the spread of disease. Doing all these things will help keep you and your loved ones healthy.". Lake County and Chicago are reporting an increased number of pertussis cases this year while other counties, including Cook, Lake, McHenry, ...
The Relationship Between Pertussis Vaccine and Central Nervous System Sequelae: Continuing Assessment | AMERICAN ACADEMY OF...
Reassessment of the role of whole-cell pertussis vaccine as a cause of permanent neurologic damage is necessitated by the 10-year follow-up of the National Childhood Encephalopathy Study (NCES) in Great Britain. The findings of this study demonstrate that infants and young children with serious acute neurologic disorders are at an increased risk of later neurologic impairment or death, irrespective of the initial precipitating event. The results, however, do not establish a causal relationship between pertussis vaccination and chronic neurologic abnormalities. The Academy reaffirms its earlier conclusion that whole-cell pertussis vaccine has not been proven to be a cause of brain damage and continues to recommend pertussis vaccination in accordance with the guidelines in the 1994 Red Book.. ...
Pertussis Vaccination of Health Care Workers | ACOEM
Health care environments have been the setting for a number of pertussis outbreaks. Health care workers are at risk for occupational infections with pertussis and at risk for inadvertently transmitting pertussis to vulnerable patients, particularly the very young. An acellular pertussis vaccine (Tdap) was approved in 2005 by the US Food and Drug Administration for adults and adolescents, and recommendations from the US Centers for Disease Control and Preventions Advisory Committee on Immunization Practices (ACIP) call for its administration to the general population and, as soon as feasible, to health care personnel who work in hospitals or ambulatory care settings and have direct patient contact. ACOEM continues its support of that recommendation based on current knowledge of the epidemiology of pertussis, its transmission characteristics, documented risk in patient care settings, and efficacy of the Tdap vaccine ...
Protection of mice against respiratory Bordetella pertussis infection by intranasal immunization with P.69 and FHA
Intranasal immunization of adult female Balb/c mice with the Bordetella pertussis antigens FHA or P.69, greatly enhanced their ability to clear B. pertussis from their lungs following aerosol challenge compared with ovalbumin-immunized controls. Low numbers of lymphocytes secreting antibodies (IgG, …
Effect of adenosine and pertussis vaccine on lymphocyte response in vitro to phytohemmaglutinin in asthmatic and non-asthmatic...
TY - JOUR. T1 - Effect of adenosine and pertussis vaccine on lymphocyte response in vitro to phytohemmaglutinin in asthmatic and non-asthmatic subjects. AU - Hiratani, M.. AU - McCall, M. K.. AU - Chaperon, E. A.. AU - Townley, R. G.. PY - 1988/1/1. Y1 - 1988/1/1. N2 - Adenosine and pertussis vaccine each significantly suppresed the in vitro lymphocyte response to photohemagglutinin (PHA) in both asthmatic and non-asthmatic subjects. On the other hand, pertussis vaccine significantly enhanced the response of the lymphocytes treated with a lower concentration of adenosine both in asthmatic and non-asthmatic subjects. It was also shown that lymphocytes from asthmatic and non-asthmatic subjects responded similarly to the modulating effect of adenosine and/or pertussis vaccine on PHA stimulation. These data give further evidence for the complex interplay of the vaccine with endogenous adenosine.. AB - Adenosine and pertussis vaccine each significantly suppresed the in vitro lymphocyte response to ...
Hypotonic-Hyporesponsive Episodes Reported to the Vaccine Adverse Event Reporting System (VAERS), 1996-1998 | ELECTRONIC...
This study is the first descriptive epidemiologic study of a large case series of children with HHE. From July 31, 1996, when the first acellular pertussis vaccine was licensed for infants in the United States, to the end of our study period (December 31, 1998), acellular pertussis vaccines became the predominant pertussis-containing vaccines in the United States. During the time of our study (1996-1998), pertussis vaccination coverage rates were stable.11Concurrently, numbers of HHE reports to VAERS decreased from 99 in 1996 to 38 in 1998. This decrease could suggest that HHE occurs less frequently after vaccination with DTaP than after whole-cell pertussis, which is similar to what has been observed in clinical trials with respect to more common adverse events, such as injection site reactions, fever, and fussiness.12-16 Our finding of a decrease in HHE during a time of increasing DTaP usage is consistent with a summary by Heijbel et al4 of HHE rates in 8 pertussis vaccine studies; however, ...
Pertussis vaccination and wheezing illnesses in young children: prospective cohort study | The BMJ
The practice of vaccination has a varied history ranging from successful eradication of smallpox to public concerns about adverse effects of vaccines. When concerns are raised about the adverse effects of vaccination, it is important to undertake a thorough investigation to either refute concerns (as in the case of the proposed links between measles vaccine and inflammatory bowel disease9 or between influenza vaccine and lung function10) or to describe accurately the magnitude of the adverse effect.. The tendency for pertussis antigens to stimulate IgE antibody responses has been well documented. What has been unclear is whether this effect is more pronounced after natural infection or after vaccination 11 12 and whether it is clinically important. Our study is the first to examine the postulated links between pertussis vaccination and wheezing illness in young children after controlling for potential confounding factors. Our key finding was the absence of any difference in the adjusted ...
More states report rising pertussis cases | CIDRAP
(CIDRAP News) Health officials in California recently reported another infant death from pertussis, as more states report rising numbers of pertussis cases.The San Diego County Health and Human Services agency announced on Jul 29 that a 1-month-old baby boy died of pertussis on Jul 27 at Rady Childrens Hospital-San Diego. The boys death is prompting new calls from health officials for parents to have themselves and their children vaccinated.
Maternity and Pregnancy By Maternity.com | What Pregnant Women Ought to Know about the Pertussis Vaccine
The pertussis vaccine is considered safe in late pregnancy. Like other vaccines, its not recommended for the first trimester, since this is the most critical time in fetal development when all of the major organs are developing and the risk for birth defects is the highest. There is no evidence that giving pregnant women the pertussis vaccine is harmful, since the vaccine is made of an inactivated (or "killed" ) virus.. (It is not recommended that pregnant women receive a vaccine with a live virus. For example, the measles-mumps-rubella (MMR) vaccine should never be given to pregnant women, since it contains live viruses and may potentially harm the developing baby.). The CDC does have one concern regarding pregnant women and the pertussis vaccine. The mothers antibodies may interfere with the babys immune response to the infant doses of pertussis vaccine, which are administered at 2 months, 4 months, and six months. There is a possibility that this leaves the baby less protected against ...
Prevention of Pertussis, Tetanus, and Diphtheria Among Pregnant and Postpartum Women and their Infants
B. pertussis, the organism that causes pertussis, elaborates multiple toxins, including tracheal cytotoxin, which damages the respiratory epithelial tissue in vitro (24), and pertussis toxin, which has systemic effects (e.g., promoting lymphocytosis) (25). Illnesses caused by other species of Bordetella are not considered preventable by available pertussis vaccines (26,27). Clinical Features B. pertussis infections and reinfections among adults and adolescents can be asymptomatic or range from a mild cough illness to the severe, prolonged cough illness of classic pertussis (28). The clinical presentation of pertussis can be similar to that for respiratory illness caused by B. parapertussis, B. bronchiseptica, B. holmseii, Mycoplasma pneumoniae, Chlamydia (Chlamydophila) pneumoniae, and multiple viral agents (e.g., adenovirus, parainfluenza virus, human metapneumovirus, influenza virus, rhinovirus, and coronavirus). The incubation period for pertussis typically is 7--10 days (range: 5--21 days) ...
diphtheria, tetanus, acellular pertussis vaccine (DTaP)
Diphtheria, tetanus, and pertussis are serious diseases caused by bacteria. Diphtheria causes a thick coating in the nose, throat, and airways. It can lead to breathing problems, paralysis, heart failure, or death. Pertussis (whooping cough) causes coughing so severe that it interferes with eating, drinking, or...
Evaluation of outbreak response immunization in the control of pertussis using agent-based modeling [PeerJ]
Background Pertussis control remains a challenge due to recently observed effects of waning immunity to acellular vaccine and suboptimal vaccine coverage. Multiple outbreaks have been reported in different ages worldwide. For certain outbreaks, public health authorities can launch an outbreak response immunization (ORI) campaign to control pertussis spread. We investigated effects of an outbreak response immunization targeting young adolescents in averting pertussis cases. Methods We developed an agent-based model for pertussis transmission representing disease mechanism, waning immunity, vaccination schedule and pathogen transmission in a spatially-explicit 500,000-person contact network representing a typical Canadian Public Health district. Parameters were derived from literature and calibration. We used published cumulative incidence and dose-specific vaccine coverage to calibrate the models epidemiological curves. We endogenized outbreak response by defining thresholds to trigger simulated
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In Spain, whole cell pertussis vaccination started in 1975, with three doses before the age of 6-7 months. Doses at 15-18 months and 4-6 years were introduced in 1996 and 2001, respectively. Spain switched to an acellular vaccine in 2005. From 1998 to 2009, pertussis incidence rates remained ≤1.5 cases/100,000 inhabitants but increased from 2010 to 7.5 cases/100,000 in 2012. Data from 1998 to 2012 were analysed to assess disease trends and susceptible populations. We defined four epidemic periods: 1998-2001 (reference), 2002-05, 2006-09 and 2010-12. In 2002-05, the incidence rate increased in individuals aged 15-49 years (IRR: 1.41 (95% CI: 1.11-1.78)) and ≥50 years (IRR: 2.78 (95% CI: 1.78-4.33)) and in 2006-09 increased also in infants aged <3 months (IRR: 1.83 (95% CI: 1.60-2.09)). In 2010-12, the incidence rate increased notably in all age groups, with IRRs ranging between 2.5 (95% CI: 2.3-2.8) in 5-9 year-olds and 36.0 (95% CI: 19.4-66.8) in 20-29 year-olds. These results, consistent with
Establishment of Diagnostic Cutoff Points for Levels of Serum Antibodies to Pertussis Toxin, Filamentous Hemagglutinin, and...
We examined the distribution of concentrations of antibodies to three B. pertussis antigens in sera from a large representative sample of more than 5,000 individuals aged 10 to 49 years who were participants in NHANES III. In this study, elevated anti-PT IgG levels were relatively infrequent (16% had levels ,20 EU), whereas elevated anti-FHA IgG and anti-FIM IgG levels (,20 EU) were more common (65 and 62%, respectively). These results suggest that an elevated level of IgG against PT may be a more specific predictor of B. pertussis infection than an elevated level of IgG against FHA or FIM. Other investigators have reported that IgG against PT is a specific indicator of recent B. pertussis infection (1, 19, 46). Although most individuals infected with B. pertussis produce antibodies to PT, FHA, and FIM, antibodies to FHA and FIM are also observed in response to infection with other Bordetella species and to cross-reacting antigens found on other bacterial species (19, 20, 37, 49, 59). ...
Department of Health | A state-wide information campaign during a pertussis epidemic in New South Wales, 2010
[email protected] - Graduate Showcase: Education for the Future: Trends of Pertussis in Kent County, Michigan: A 20-year...
Background: Pertussis incidence is low in Kent County, Michigan in comparison with surrounding counties, and we suspect that the rates are increasing. We hypothesized that pertussis incidence has increased for all demographic characteristics, especially since the year 2005. Methods: A retrospective design was used in which data between the years 1996-2015 was used as gathered from the Michigan Disease Surveillance System (MDSS). Demographic characteristics were examined and incidence was compared to previous years in order to examine trends. Additionally, incidence rates pre- and post-2005 were compared. Data were analyzed using Poisson regression models in SPSS. Results: This sample included 189 confirmed cases. The sample was 49.2% male, 65.1% White and 2.7% non-White. The greatest proportion of cases were seen in the less than one year age group (n=80; 42.3%), with the second largest percentage seen in the 1-19 years age group (n=74; 39.2%). Grand Rapids and East Grand Rapids had the highest
What's the difference between all the vaccines containing diphtheria and tetanus toxoids and pertussis vaccine? - Answered by...
Dr. Diamond responded: Ingredients. The acellular pertussis vaccines is now recommended to be given at least once to all adults . There is no recommendation for more than 1 adult booster, but i would not be surprised to see it given for every booster (7-10 yrs) in the future.The other differences are related to the specific type of antigens and quatity in each vaccine.Antigens are the material that triggers your immunity.
Bordetella pertussis Antibodies, IgA, IgG, & IgM
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Life Choice: November 2015
In Sweden, general vaccination with a whole cell pertussis vaccine was recommended from 1953. In 1979 the recommendation was withdrawn because the Swedish-made vaccine had become ineffective. In order to determine the incidence of the disease in a non-vaccinating country, 400 children born in 1980 were randomly selected from the population register of Goteborg, Sweden. The parents of the children were interviewed in 1990, when the children were 10 years old. The parents of 377 children could be reached, and of those 372 were not vaccinated against pertussis. Of the nonvaccinated children 61% had experienced clinically typical whooping cough; 195 (119 with and 76 without a history of whooping cough) agreed to donate a serum sample for determination of antibodies against pertussis toxin, filamentous hemagglutinin and pertactin. Of the children with a history of whooping cough, 91% had antibodies against pertussis toxin, as had 64% of the children without a history of disease. All but 3 children ...
Pertussis | Rudolph's Pediatrics, 23e | AccessPediatrics | McGraw-Hill Medical
B pertussis produces numerous virulence factors, including toxins and attachment agents, many of which are antigenic and included in the acellular vaccine. The link of each virulence factor to clinical illness has been difficult to elucidate due to lack of an animal model for experimentation. However, a recently developed model in infant baboons has the potential to address unanswered questions. The bacteria attach to ciliated epithelial cells of the respiratory tract, induce ciliary paralysis and local inflammation, and thicken and decrease clearance of secretions. B pertussis is not invasive. Pertussis toxin, necessary but not sufficient to cause clinical pertussis, is secreted by the bacteria and affects G-protein function, which prevents migration of lymphocytes to the area of infection, and inhibits the function of neutrophils, macrophages, monocytes, and lymphocytes. Adenylate cyclase toxin invades phagocytes and induces high levels of cyclic adenosine monophosphate (AMP), which impairs ...
Pertussis Vaccine Market: Trends and Forecast 2016 - 2024
Vaccination Against Pertussis, Tetanus and Diphtheria in Patients Suffering From Rheumatoid Arthritis - Full Text View -...
Pertussis is an acute respiratory infection caused by Bordetella pertussis. Rates of recent B. pertussis infection between 8%--26% have been reported among adults with cough illness of at least 5 days duration who sought medical care. The CDC recommends vaccinating patients aged 15 to 64 years old, once in 10 years. Although acellular vaccines such as BOOSTRIX have been evaluated in healthy population, the safety and efficacy of this vaccine in patients suffering from rheumatic diseases have not been established.. Study population : 50 Rheumatoid Arthritis (RA) patients and 5 healthy controls. Evaluation : the evaluation will be performed on week 0 and 4-6 weeks later. In terms of safety, the patients will be evaluated according to the Disease Activity Index (DAS). Blood will be drawn at each visit at tested for humoral response to tetanus and pertussis. ...
Vaccination Against Pertussis, Tetanus and Diphtheria in Patients Suffering From Rheumatoid Arthritis - Full Text View -...
Pertussis is an acute respiratory infection caused by Bordetella pertussis. Rates of recent B. pertussis infection between 8%--26% have been reported among adults with cough illness of at least 5 days duration who sought medical care. The CDC recommends vaccinating patients aged 15 to 64 years old, once in 10 years. Although acellular vaccines such as BOOSTRIX have been evaluated in healthy population, the safety and efficacy of this vaccine in patients suffering from rheumatic diseases have not been established.. Study population : 50 Rheumatoid Arthritis (RA) patients and 5 healthy controls. Evaluation : the evaluation will be performed on week 0 and 4-6 weeks later. In terms of safety, the patients will be evaluated according to the Disease Activity Index (DAS). Blood will be drawn at each visit at tested for humoral response to tetanus and pertussis. ...
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Pertussis is most severe among unvaccinated infants (< 1 year of age), and still leads to several reported deaths in the Netherlands every year. In order to avoid pertussis-related infant morbidity and mortality, pertussis surveillance data are used to guide pertussis control measures. However, more insight into the accuracy of pertussis surveillance and control, and into the range of healthcare and public health-related factors that impede this are needed. We analysed a unique combination of data sources from one Dutch region of 1.1 million residents, including data from laboratory databases and local public health notifications between 2010 and 2013. This large study (n = 12,090 pertussis tests) reveals possible misdiagnoses, substantial under-notification (18%, 412/2,301 laboratory positive episodes) and a delay between patient symptoms and notification to the local public health services (median 34 days, interquartile range (IQR): 27-54). It is likely that the misdiagnoses, under-notification and
TIBBS » Respiratory Pathogens FDA Postdoc
CBER, FDA. A postdoctoral fellow position is immediately available within the Laboratory of Respiratory Pathogens at the FDAs Center for Biologics Evaluation & Research in Silver Spring, Maryland. The candidate will have the opportunity to participate in a well-funded research program utilizing the baboon model of pertussis to advance our understanding of pertussis disease and immunology and will be expected to conduct independent research with a focus on pathogenesis and the host response to Bordetella pertussis infection. ...
A cocktail of humanized anti-pertussis toxin antibodies limits disease in murine and baboon models of whooping cough | Science...
Before widespread vaccination, a number of blood products and polyclonal immunoglobulins were used to treat human pertussis, some with positive, albeit poorly controlled, results (26). More recent preparations were developed on the presumption that PTx is responsible for the severe symptoms of disease, and therefore, preparations enriched in anti-PTx antibodies would mitigate the symptoms. However, this clinical strategy is limited by the expectation that only a fraction of PTx-specific antibodies in a polyclonal preparation would be neutralizing. In contrast, the monoclonal antibodies used in this study were selected specifically for their capacity to neutralize PTx, individually and synergistically. The initial feasibility data using murine and baboon models reported here support the concept of passive immunotherapy to neutralize PTxs pathological effects.. Previously, two polyclonal anti-PTx preparations elicited by immunization with inactivated PTx were assessed in controlled trials. One ...
Just the Vax: August 2010
His opinion should be qualified by evidence and it isnt. Vaccine efficacy has nothing to do with pertussis being a stubborn germ; there is no such accepted or recognised term. The vaccine efficacy, which incidentally is ~63-100%, is due to limitations within the vaccine construct and host immune response. Naturally-acquired immunity does not confer much longer immunity than the vaccine. Which is all more reason why very high vaccine uptake amongst those eligible is crucial to protect vulnerable infants that are too young to receive the vaccine or complete vaccination.. Lets look at some recent figures from the 2010 pertussis outbreak. Here are the California Department of Public Healths pertussis statistics for 2010 by county and here are vaccine exemptions for 2009 kindergarten entry. There has been much finger-pointing at Marin County due to their high rates of vaccine refusal. Not only has their vaccine exemption rate nearly doubled since the last pertussis outbreak to over 7%, but ...
A search for serologic correlates of immunity to Bordetella pertussis cough illnesses. - PubMed - NCBI
Just the Vax Forum - TDaP vaccination while breastfeeding?
July 19, 2010) In a typical year, about six to eight cases of pertussis, or whooping cough, are reported to the Health Department of Northwest Michigan in its four-county service area. 2010, however, is not a typical year. From January through June 2010, there were 10 cases of pertussis in Emmet County alone. With pertussis cases also reported in Antrim, Charlevoix, and Otsego counties, anyone who is not fully immunized against the vaccine-preventable disease may be exposed.. Public health officials encourage adults to check their childrens, and their own, immunization records. Vaccination not only protects individuals against infections, it prevents them from spreading illness to others whose immunizations are not up-to-date, particularly babies.. "When infants are diagnosed with pertussis infection, the likely source is undiagnosed adults or older children in the home,"" said Pat Fralick, Director of Family & Community Health Services for the Health Department of Northwest Michigan. She said ...
Pertussis outbreak declared in west part of AHS South Zone | Alberta Health Services
Cost-effectiveness of analysis of pertussis vaccination during pregnancy in Japan - VoICE
Orange County, California - Pregnant Women
Tdap-Pregnant women should get a pertussis booster shot (Tdap) with every pregnancy irrespective of their prior history of receiving Tdap. Immunize between 27 and 36 weeks gestation to maximize the transfer of maternal antibody to the infant. Other close contacts of infants: Due to statewide increases in cases of pertussis infections, the California Department of Public Health recommends that birth hospitals and other immunizers provide Tdap to all close contacts of infants without documentation of Tdap vaccination, especially parents and childcare providers (including grandparents). Contacts should be immunized before mother and baby are discharged after birth, regardless of when the contacts received any prior doses of Td ...
CiNii Articles - KAMIYA Hitoshi
Pertussis Vaccine aka Whooping Cough Vaccine - Koren Wellness
Sarah Michelle Gellar advocates for pertussis vaccine - Minor Topics
Im a mom trying to keep my kids healthy, but I also have access to so much information that I can then go through it all and make it easier for people to understand. Youre talking about an illness that doesnt have to exist. The only way to help fight against it is to get the vaccine, and thats a simple way," Gellar continued.. Whooping cough is on the rise in the U.S., with more than 41,000 cases developing in 2012, causing at least 18 deaths according to the CDC.. Gellar also stated this alarming statistic, "Eighty percent of the children who came down with it, they can track it back to a family member that brought it in, and 50 percent were the actual parents. I know theres nothing worse as a new parent than you thinking that you got your child sick…Its a simple vaccination for an adult to get every five years, and thats it. Its the only safe way to prevent the child from getting the disease.". Gellar said it is important for adults to get the pertussis vaccine to protect babies ...
Pertussis Microbe Outsmarts the Vaccines As Experts Argue About Why - NVIC Newsletter
pertussis vaccine - Immunization & Vaccine - MedHelp
"Pertussis , Whooping Cough , Causes and Transmission , CDC". www.cdc.gov. 2017-08-18. Retrieved 2017-12-05. "Principles of ... Bordetella pertussis (Pertussis) is transmitted by cough from human reservoir to susceptible host through direct droplet spread ... they can spread from coughing, sneezing, and talking. Neisseria gonorrhoeae (Gonorrhea) is transmitted by sexual contact ...
List of infectious diseases
Chicago International Film Festival
Whooping cough, also called pertussis, is a contagious disease that affects the respiratory tract. The infection is caused by a ... "Pertussis , Whooping Cough , Complications , CDC". www.cdc.gov. Retrieved 2016-02-16. "Vaccines: VPD-VAC/Pertussis/main page". ... Hartzell, Joshua D.; Blaylock, Jason M. (2014-07-01). "Whooping Cough in 2014 and Beyond: An Update and Review". Chest. 146 (1 ... whooping cough). While the US recommends a booster for tetanus every 10 years, other countries, such as the UK, suggest just ...
George Siber bibliography
Whooping cough is also met with." Indian children were removed to white boarding schools and diagnosed with a wide range of ... In 1889, their crops were a failure ... Thus followed epidemics of measles, grippe [influenza], and whooping cough Pertussis, ... diseases, including tuberculosis, trachoma, measles, smallpox, whooping cough, influenza, and pneumonia. ... Exposure to diesel exhaust irritates the eyes, nose, throat and lungs, causing coughs, headaches, light headedness and nausea, ...
... "whoop". Infants less than six months also may not have the typical whoop. A coughing spell may last a minute or more, producing ... but whooping cough has been found among wild gorillas. Several zoos have learned to vaccinate their primates against whooping ... Uncertainties of B. pertussis and whooping cough as a zoonotic disease have existed since around 1910, but in the 1930s, the ... At least some primate species are highly sensitive to B. pertussis, and develop a clinical whooping cough in high incidence ...
"ACCC tackles Homeopathy Plus! Whooping Cough claims". Australian Competition and Consumer Commission. 2012-05-03. Retrieved ... alternative to vaccination for conditions including whooping cough, along with claims that homeopathy is superior to ... state that Homeopathic Treatments are safe and effective as an alternative to the Vaccine for the Prevention of Whooping Cough ...
She is credited as co-developer of the pertussis (whooping cough) vaccine. She started treating children in 1928. By the time ... Denmark is credited as co-developer of the pertussis (whooping cough) vaccine, with support from Eli Lilly and Company, and ... 1935, the Fisher Award for "outstanding research in diagnosis, treatment, and immunization of whooping cough for her work on ... "Whooping cough vaccine". Am J Dis Child. 63 (3): 453-466. doi:10.1001/archpedi.1942.02010030023002. Denmark, Leila Daughtry ( ...
Immunisation Awareness Society
... whooping cough] vaccine is useless and no matter how many boosters you have it is not going to stop the occurrence of whooping ... The IAS has regularly publicly campaigned against vaccination during epidemics: during a 2011 whooping cough epidemic, IAS ... Goodwin, Eileen (6 October 2011). "Whooping cough vaccination 'cocooning' call". Otago Daily Times. Staff (11 July 2009). " ... cough and the best bet is for parents to educate themselves on how to look after their children should they develop it. In July ...
Jafar Ibn Auf Pediatric Hospital
She contracted and survived whooping cough when she was five, leading to her involvement in science in her adulthood. After ... "Grace Eldering; Helped Develop Whooping Cough Vaccine". Los Angeles Times. September 3, 1988. Retrieved August 23, 2015. Burns ... Kendrick and Eldering started a "cough plate diagnostic service" on November 1, 1932, whereby cough plates of suspected ... known for her involvement in the creation of a vaccine for whooping cough along with Pearl Kendrick. Grace Eldering was born in ...
Whooping cough is very contagious and cases are slowly increasing in the United States despite vaccination. Symptoms include ... This family is also known as Ptx and contains the toxin responsible for whooping cough. Pertussis toxin is secreted by the gram ... The bacterium Bordetella pertussis was first identified as the cause of whooping cough and isolated by Jules Bordet and Octave ... paroxysmal cough with whooping and even vomiting. ...
Wikipedia:List of articles all languages should have/Expanded/Biology and health sciences - Simple English Wikipedia, the free...
Children's Hospital of Philadelphia
Infection - Simple English Wikipedia, the free encyclopedia
"Finding aid for the Michigan women and the whooping cough vaccine collection Collection 328" (PDF). Retrieved 6 March 2015. " ... "How 2 women scientists created whooping cough vaccine". Michigan Live. Retrieved 5 March 2015. ""A Whole Community Working ... and the world through her work in the development of a vaccine against whooping cough..." Gordon was inducted into the Michigan ...
"Whooping cough outbreak: Pregnant women to be vaccinated". BBC News. Archived from the original on 29 September 2014. "Tetanus ... Acellular pertussis vaccine (aP) with three or more antigens prevents around 85% of typical whooping cough cases in children. ... Zhang, L; Prietsch, SO; Axelsson, I; Halperin, SA (Sep 17, 2014). "Acellular vaccines for preventing whooping cough in children ...
Elizabeth Scott (politician)
Healthcare in Brazil
Ellis Island Immigrant Hospital
History of medicine in the United States
Garais klepus - Vikipēdija
2012). "Symptomatic treatment of the cough in whooping cough". Cochrane Database Syst Rev (5) ... Whooping cough in school age children presenting with persistent cough in UK primary care after introduction of the preschool ... Whooping cough in school age children with persistent cough: prospective cohort study in primary care. BMJ, 2006 Jul 22;333( ... Symptomatic treatment of the cough in whooping cough. Cochrane Database Syst Rev. 2014 Sep 22;9: CD 00 3257. doi: 10.1002/ ...
Vaccine - Simple English Wikipedia, the free encyclopedia
आइसीडी-१० अध्याय ब - विकिपीडिया
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Great Famine (Ireland)
백일해 - 위키백과, 우리 모두의 백과사전
"Pertussis (Whooping Cough) Fast Facts". 》cdc.gov》. 2014년 2월 13일. 2015년 2월 7일에 원본 문서에서 보존된 문서. 2015년 2월 12일에 확인함.. ... "Pertussis (Whooping Cough) Causes & Transmission". 》cdc.gov》. 2014년 9월 4일. 2015년 2월 14일에 원본 문서에서 보존된 문서. 2015년 2월 12일에 확인함.. ... "Pertussis (Whooping Cough) Specimen Collection". 》cdc.gov》. 2013년 8월 28일. 2015년 2월 8일에 원본 문서에서 보존된 문서. 2015년 2월 13일에 확인함.. ... "Symptomatic treatment of the cough in whooping cough". 》The Cochrane Database
List of vaccine topics
위키백과:미번역 문서/의학 - 위키백과, 우리 모두의 백과사전
વર્ણકોષાશય - વિકિપીડિયા
Northwestern Lake Forest Hospital
In some birds (e.g. the whooper swan, Cygnus cygnus, the white spoonbill, Platalea leucorodia, the whooping crane, Grus ... Irritation of nerve endings within the nasal passages or airways, can induce a cough reflex and sneezing. These responses cause ... The automatic rhythmical breathing in and out, can be interrupted by coughing, sneezing (forms of very forceful exhalation), by ... During coughing, contraction of the smooth muscle in the airway walls narrows the trachea by pulling the ends of the cartilage ...
Lister Institute of Preventive Medicine
Head injury Whooping cough or other extreme sneezing or coughing Severe hypertension LASIK Acute hemorrhagic conjunctivitis ( ... Such a hemorrhage may be caused by a sudden or severe sneeze or cough, or due to high blood pressure or as a side effect of ... or coughing) Zygoma fracture (results in lateral subconjunctival hemorrhage) Subconjunctival hemorrhages in infants may be ...
A looming whooping cough epidemic - that
... s totally preventable. Imagine coughing so hard and for so long that you turn blue and ... Pertussis, or whooping cough, can do that to an infant. The disease is caused by the bacterium Bordetella pertussis and causes ... Helena Rho: A looming whooping cough epidemic - thats totally preventable. Helena Rho, National Post Wire Services , February ... Kevork Djansezian/Getty ImagesA school nurse prepares a vaccine against whooping cough before giving it to students at Mark ...
Pertussis case confirmed at Whitworth Elementary | Polk Couny Itemizer-Observer mobile site
If a cough persists longer than two weeks - or causes gagging or vomiting - that person should be tested for whooping cough, ... In children, coughing fits are often followed by a whooping sound as they try to catch their breath. ... DALLAS - A child at Whitworth Elementary School has been positively diagnosed with a case of pertussis, or whooping cough. The ... It is spread by coughing and sneezing.. "It starts with a mild cough and can be very similar to cold-like symptoms," said ...
The City of Lubbock Health Depart. issues public health advisory - KCBD NewsChannel 11 Lubbock
Pertussis, which is also known as Whooping Cough, is spread by infected persons coughing or sneezing while in close contact ... The cough worsens, becoming severe after 1-2 weeks. Children with the disease cough violently and rapidly, over and over, until ... The disease starts like the common cold, with runny nose or congestion, sneezing, and sometimes mild cough or fever. ... Parents can also help protect infants by keeping them away from anyone who has cold symptoms or is coughing. ...
eDrug Update - March 2017
Pregnancy and Whooping Cough, Rationale: Why Vaccinate Pregnant Women? Centers for Disease Control and Prevention website. ... Pertussis, commonly known as "whooping cough," is a highly contagious respiratory disease caused by the bacteria Bordetella ... Since the pertussis vaccine has been available, infant mortality due to whooping cough has decreased drastically. Nonetheless, ... Although coughing is the most prevalent symptom, many infants with pertussis do not show symptoms of coughing. The younger the ...
Epidemic curve of a pertussis outbreak, September 2010 | Open-i
Pertussis | Whooping Cough | Home | CDC
Hear how the cough may sound. It is important to know that not everyone with pertussis coughs or "whoops". ... After cough fits, someone with pertussis often needs to take deep breaths, which result in a "whooping" sound. Pertussis can ... Learn why Laura decided to get the whooping cough vaccine in her 3rd trimester of pregnancy and how her baby girl was born with ... Pertussis, also known as whooping cough, is a highly contagious respiratory disease. It is caused by the bacterium Bordetella ...
Pertussis | Pregnancy and Whooping Cough | Home | CDC
Get vaccinated while pregnant to protect you and your baby from whooping cough. ... Listen to, watch, or download free whooping cough materials, including resources to promote the whooping cough vaccine ... Whooping cough (pertussis) is a very contagious disease that can be deadly for babies. It spreads from person to person, ... Pregnancy and Whooping Cough Home * For Pregnant Women ... Learn how you can help protect your baby from whooping cough.. ...
Whooping-cough immunisation. | The BMJ
Whooping Cough: On the Rise
... or whooping cough, seems to be making a comeback. The CDC recently reported the highest number of cases in nearly 40 years, and ... Should I be worried about them giving whooping cough to my baby? MIDDLEMAN: If a teenager has a cough or a cold, its best for ... Why is whooping cough making a comeback - or did it ever really go away? MIDDLEMAN: Thats a great question, and a complicated ... Pertussis, or whooping cough, seems to be making a comeback. The CDC recently reported the highest number of cases in nearly 40 ...
NEAHRING: Whooping Cough
Whooping cough, also known as pertussis, is a respiratory tract infection with a paroxysmal cough, caused by the bacterium ... Some people have a persistent hacking cough without the characteristic whoop noise, and infants may not even get a cough at all ... whooping cough can have a long and irritating course. The Chinese have nicknamed pertussis the cough of 100 days since it ... NEAHRING: Whooping Cough. Happy New Year! Usually, the start of a new year is a time of quiet reflection for me, a chance to ...
Treatment of Whooping-cough | The BMJ
Childhood Diseases: Pertussis, or Whooping Cough
Once the whooping stage begins, antibiotics dont work.. Disease Diction. Whooping cough got its name from the whooping sound ... Symptoms of whooping cough generally include runny nose and a cough that gets worse and worse. Violent coughing spells can end ... Childhood Diseases: Pertussis, or Whooping Cough. Pertussis, or Whooping Cough. Childhood Diseases. *Introduction ... Whooping cough is spread through the air, making it particularly infectious.. Excerpted from The Complete Idiots Guide to ...
Whooping Cough: Causes, Symptoms, Treatment and Prevention
... a bacterial infection that causes a cough and cold-like symptoms. Vaccines may help prevent it. ... WebMD explains whooping cough (also known as pertussis), ... Whooping Cough: What Happens Whooping cough (also known as ... Whooping Cough) Diagnosis and Treatment;" "Pertussis (Whooping Cough) Vaccination;" and "Protect Babies from Whooping Cough ( ... Whooping Cough: What Happens. If a person with whooping cough sneezes, laughs, or coughs, small droplets that contain the ...
Whooping Cough Treatment, Causes, Symptoms, Vaccine, Diagnosis
Whooping cough gets its name from the high-pitched whoop sound that follows a series of rapid coughs. ... Read about the whooping cough vaccine (DTaP, Tdap), treatment, symptoms, stages, causes (Bordetella pertussis), and prevention ... Whooping Cough Symptoms and Signs. The term "whooping cough" is based on the characteristic noise made as the person at the end ... Is Whooping Cough Highly Contagious? *Whooping cough (pertussis) is an acute, highly contagious bacterial infection. The ...
HON - News : Health Tip: Understanding Whooping Cough
Health Tip: Understanding Whooping Cough (HealthDay News) -- Whooping cough is an infection of the respiratory system caused by ... Nemours offers this additional information about whooping cough:. *It can be prevented by the whooping cough vaccine, which is ... can trigger coughing spells that can last more than a minute.. The childs face may turn red or purple, and the child may vomit ... People who come into close contact with someone who has whopping cough should be given an antibiotic to help prevent the ...
Whooping Cough Makes Whopping Comeback | Live Science
Whooping cough, once nearly eliminated in the 1970s, is back and might reach a 50-year high in 2010, largely the result of poor ... But whooping cough, named for the high-pitched "whoop" a person makes when inhaling, has made a comeback, with an incidence ... By the 1970s, through vaccinations, whooping cough was as endangered as the whooping crane, with only about 0.000005 percent of ... Whooping cough sounds fantastically antiquated, up there with scurvy and St. Vitus Dance - diseases you didnt think anyone in ...
Whooping cough in children | BabyCenter
... theres still a small chance of getting whooping cough. Learn to recognize the signs. ... For more information, see our article on whooping cough in babies.. How long does whooping cough last?. Whooping cough can last ... How is whooping cough diagnosed?. To find out if your child has whooping cough, the doctor may:. *listen to your childs cough ... Caring for whooping cough at home. If your child is diagnosed with whooping cough, there are a few things you can do to help ...
Watch out for whooping cough
Marys Hospital, about whooping cough and how parents of young children can keep the disease at bay. ... Whooping cough develops slowly. The Bordetella pertussisbacteria, which causes whooping cough and is passed through infected ... Treating whooping cough. Whooping cough can be treated successfully with antibiotics and most people make a full recovery. ... If you catch whooping cough but dont take antibiotics, you can infect others for three weeks after your whooping coughing ...
Whooping Cough's Comeback Raises Questions
Whooping Coughs Comeback Raises Questions How states decisions to not require vaccinations and general budget cuts to public ... A century ago, whooping cough spread dread across the country, causing more than 5,000 deaths a year. But after scientists ... This years whooping cough outbreak shows how fast disease can spread. The 1918 Spanish flu pandemic, which killed more than 50 ... The Washington whooping cough emergency, fortunately, didnt rise to that scale. But it does raise two very worrisome points. ...
Whooping Cough Articles, Photos, and Videos - Los Angeles Times
Related "Whooping Cough" Articles. L.A. Now Vaccination rate jumps in California after tougher inoculation law. Soumya ... Whooping Cough. Vaccination rate jumps in California after tougher inoculation law. The vaccination rate for Californias ... Amid whooping cough epidemic, LAUSD offers free vaccines. Sara Hayden. Starting middle school comes with a whole host of ... Vaccination aversion has fueled measles and whooping cough outbreaks, study finds. Melissa Healy ...
Pertussis Whooping Cough
The cough can persist for 6 weeks or longer. In small infants, the cough can be minimal or nonexistent and they may become ... Pertussis, also known as whooping cough, is a vaccine-preventable respiratory illness caused by the bacteria Bordetella ... Later symptoms include the gradual onset of coughing, which develops into fits of rapid coughs, sometimes with a classic ... inspiratory whoop as the patient gasps for air, and sometimes with post-coughing vomiting and exhaustion. ...
Pertussis (Whooping Cough)
... Facts About Pertussis. Whooping cough (also called pertussis), is a serious infection that spreads ... Whooping cough can even lead to cracked ribs, pneumonia, or hospitalization. In the past, whooping cough was largely controlled ... Get Vaccinated to Help Prevent Whooping Cough. Learn about the burden of pertussis (whooping cough) in the US and the ... Whooping cough causes coughing spells that can affect breathing, eating and sleeping. The infection can even lead to cracked ...
Whooping Cough Articles, Photos, and Videos - Orlando Sentinel
Whooping Cough. Whooping cough is still around and a danger to babies. A month ago, Yassiris Diazs son developed what seemed ... Confirmed case of whooping cough at local high school. CBS12. The Health Department has confirmed a case of whopping cough at ... Curbelo comes down with whooping cough. The Associated Press. WASHINGTON - U.S. Rep. Carlos Curbelo, R-Miami, has been ... Whooping cough is still around and a danger to babies. Naseem S. Miller ...
Whooping Cough (Pertussis) (for Parents) - Main Line Health
Pertussis is characterized by severe coughing spells that end in a whooping sound when the person breathes in. It can be ... Whooping cough causes severe coughing spells, which can sometimes end in a "whooping" sound when the child breathes in. ... Giving cough medicine probably will not help, as even the strongest usually cant relieve the coughing spells of whooping cough ... Call the doctor if you think that your child has whooping cough or has been exposed to someone with whooping cough, even if ...
Whooping cough vaccine not associated with preterm delivery
Whooping cough most commonly affects infants. Whooping cough is a contagious respiratory disease that is characterized by ... of children aged 5-15 visiting their doctor with a persistent cough have whooping cough, despite nearly all children being ... Whooping cough vaccine not associated with preterm delivery. Written by James McIntosh. on November 12, 2014 ... As babies in the US do not receive their own whooping cough vaccines until they are 2 months old, the provision of early, short ...
Whooping cough outbreaks most in decades - UPI.com
... cases of the deadly disease whooping cough are appearing more frequently than in decades and public health officials worry the ... It can cause them to turn blue from lack of oxygen, due to seemingly unending coughing fits, which result in a whooping kind of ... 23 (UPI) -- Across the United States, cases of the deadly disease whooping cough are appearing more frequently than in decades ... The trend alarms officials because whooping cough, formally known as pertussis, was once a devastating disease in the United ...
Whooping cough outbreak declared in Miramichi | CBC News
... commonly known as whooping cough, were reported in the Miramichi region. ... Whooping cough outbreak declared in Miramichi. The regional medical officer of health has declared an outbreak after eight ... The eight cases of whooping cough are in four Miramichi schools. Two schools, North and South Esk Elementary and Dr. Losier ... They can include sneezing, runny nose, low-grade fever and a mild cough that gradually worsens, leading to serious coughing ...
Flipboard: California declares whooping cough epidemic
The agency says that there were 3,458 whooping cough cases reported between January 1 and June 10, well ahead of the number of ... California is being hit hard with a whooping cough epidemic, according to the states public health department, with 800 cases ... California declares whooping cough epidemic. CNN - By Jen Christensen, CNN. California is being hit hard with a whooping cough ... The agency says that there were 3,458 whooping cough cases reported between January 1 and June 10, well ahead of the number of ...
Whooping cough: Symptoms, treatment and causes
Whooping cough is a highly contagious bacterial infection transferred through airborne droplets. Get expert advice on symptoms ... What is whooping cough?. Whooping cough (pertussis) is still a very serious disease when it occurs in children under the age of ... What causes whooping cough?. Whooping cough is caused by a bacteria (Bordetella pertussis) and is one of the most contagious ... Whooping cough (pertussis). Whooping cough is one of the most contagious bacterial infections and can lead to other conditions ...
Immunized People Getting Whooping Cough | KPBS
Most of the people who got whooping cough in San Diego County so far this year were up to date with their immunizations, ... More Teens Getting Whooping Cough Since Vaccine Change. Jan. 19, 2015. * Record Number Of Whooping Cough Cases In San Diego ... Most of the people who got whooping cough in San Diego County so far this year were up to date with their immunizations, ... Record Number Of Whooping Cough Cases In San Diego County In 2014. Feb. 27, 2015. ...
10 infants dead in California whooping cough outbreak - CNN.com
Whooping cough, also known as pertussis, has claimed the 10th victim in California, in what health officials are calling the ... Video: What is whooping cough?. Pertussis, or whooping cough, is a highly contagious disease caused by bacteria that can lead ... Adults usually dont have the whoop cough, so they may not think they have pertussis. Patti recommends if someone has a cough ... Listen to what whooping cough sounds like. Parents and doctors can often miss the initial symptoms of pertussis in the youngest ...
Whooping cough protection fades fast after Tdap, study finds - CNN
Whooping cough reaches epidemic level in California - Los Angeles Times
On average, state epidemiologists expect to see 80 to 100 cases of whooping cough each month. In the last two weeks, California ... On average, state epidemiologists expect to see 80 to 100 cases of whooping cough each month. In the last two weeks, California ... For the first time in four years, California is experiencing a statewide epidemic of pertussis, or whooping cough, with infants ... Its partially for this reason that whooping cough is cyclical: It reaches epidemic levels every three to five years. ...
Pertussis (Whooping Cough) - Epidemiology
What is pertussis (whooping cough)?. Pertussis is a very contagious disease characterized by severe coughing and caused by the ... The cough lasts 1-2 weeks and then worsens. The second stage includes uncontrolled coughing followed by a whooping noise when ... During these severe coughing spells, a person might vomit, or the lips or face may look blue from a lack of oxygen. Between ... These bacteria spread through the air in droplets produced by sneezing and/or coughing. Persons in the early stage of illness ...
ContagiousKnown as whooRunnyBordetellaSpellsCaliforniaBacteriaComplicationsHigh-pitchedSymptoms of whoopOutbreak of whoopAdultsUncontrollablePrevent whoopAntibioticsBacteriumViolentMucusBreatheCharacteristic whoopRapid coughsDeathsVaccinationsTdapCase of whoopChild has whoopVaccine for whoopProtection against whoopPersistentInfectiousDiagnosisExhaustionCaught whoopOutbreaks of whoopMilderBacterialTetanusSneezesBoutsPneumoniaParoxysmalSoundOfficialsPregnancyImmunizationEpidemicsComebackCommonlyPertussis vaccineIncidence of whoopRecover from whoop
- Pertussis, also known as whooping cough , is a highly contagious respiratory disease. (cdc.gov)
- Whooping cough (pertussis) is a very contagious disease that can be deadly for babies. (cdc.gov)
- Pertussis is highly contagious and spreads easily from person to person through coughing or sneezing or sometimes just sharing a breathing space in close quarters. (courierpress.com)
- Whooping cough is a very contagious and dangerous respiratory infection caused by the Bordetella pertussis bacterium. (infoplease.com)
- Whooping cough is a highly contagious disease that can strike people of any age but is most dangerous to children. (yahoo.com)
- Is Whooping Cough Highly Contagious? (medicinenet.com)
- Whooping cough ( pertussis ) is an acute, highly contagious bacterial infection. (medicinenet.com)
- What is the contagious period for whooping cough? (medicinenet.com)
- A person infected with pertussis is highly contagious (can spread the infection to others) from the onset of symptoms to around three weeks after the onset of the coughing episodes. (medicinenet.com)
- Whooping cough, also known as pertussis, is a highly contagious bacterial infection that inflames the lungs and airways. (babycenter.com)
- People with whooping cough are most contagious during the early stages of the disease, up until about 2 weeks after the coughing fits start. (babycenter.com)
- Pertussis is extremely contagious and is spread from person to person by coughing or sneezing. (tn.gov)
- WASHINGTON - U.S. Rep. Carlos Curbelo, R-Miami, has been diagnosed with whooping cough, a rare and contagious disease that is officially known as pertussis. (orlandosentinel.com)
- Maryland public health officials, monitoring an uptick in the number of whooping cough cases, are urging parents to make sure children are immunized against the highly contagious respiratory infection as the school year draws near. (orlandosentinel.com)
- Infected people are most contagious during the earliest stages of the illness for up to about 2 weeks after the cough begins. (kidshealth.org)
- Whooping cough is a contagious respiratory disease that is characterized by uncontrollable and violent coughing. (medicalnewstoday.com)
- Whooping cough is one of the most contagious bacterial infections and can lead to other conditions such as bronchitis and pneumonia. (netdoctor.co.uk)
- Whooping cough is caused by a bacteria (Bordetella pertussis) and is one of the most contagious bacterial infections. (netdoctor.co.uk)
- Pertussis, or whooping cough, is a highly contagious disease caused by bacteria that can lead to severe upper respiratory infections. (cnn.com)
- Pertussis is a very contagious disease characterized by severe coughing and caused by the bacteria Bordetella pertussis . (virginia.gov)
- Dr. Eugene Shapiro of Yale University, writing in the Journal of the American Medical Association, said while there is speculation recent outbreaks of whooping cough are linked to the vaccines' waning immunity over time, there is no definitive evidence that this is the primary or sole reason for increases in reported cases of pertussis -- a highly contagious bacterial disease. (upi.com)
- Pertussis (a.k.a whooping cough) is a highly contagious, potentially fatal disease characterized by violent coughing attacks. (boston.com)
- Whooping cough, or pertussis, is a highly contagious respiratory illness. (dailyherald.com)
- These bacteria are highly contagious and are passed from person to person through coughing and sneezing and close contact. (labtestsonline.org)
- The disease, caused by the bacterium Bordetella pertussis , is spread via coughing or sneezing and is highly contagious. (newscientist.com)
- Whooping cough (also known as pertussis) is a highly contagious illness that can be life threatening. (hse.ie)
- Whooping cough (also known as pertussis or 100-day cough ) is a highly contagious bacterial disease . (wikipedia.org)
- Whooping cough is a highly contagious bacterial infection of the respiratory tract that affects the nose, throat and lungs. (scientificamerican.com)
- Whooping cough is very contagious and can be especially serious for young children," county Public Health Director Wendel Brunner said in a statement. (sfgate.com)
- A highly contagious disease, caused by the bacterium Bordetella pertussis , whooping cough is known for its severe coughing attacks with a characteristic 'whoop' at the end. (abc.net.au)
- Pertussis, commonly known as "whooping cough," is an extremely contagious bacterial disease spread through coughing. (eastbayexpress.com)
- Whooping cough (pertussis) is a highly contagious bacterial infection that can affect people of all ages, but is most severe in babies. (mydr.com.au)
- Whooping cough is highly contagious at this stage, but difficult to diagnose. (mydr.com.au)
- Pertussis, commonly referred to as whooping cough, is a highly contagious respiratory disease caused by the Bordetella (B.) pertussis bacterium. (nvic.org)
- Whooping cough, also known as pertussis, is a highly contagious bacterial infection that can strike people of any age but is most dangerous to children, particularly babies under 1 year old. (thedoctorstv.com)
- It is highly contagious at this stage, but difficult to diagnose, as whooping cough can be mistaken for bronchitis. (mydr.com.au)
- Pertussis, which is more commonly known as whooping cough, is a highly contagious bacterial infection of the respiratory system. (fortherecordmag.com)
- Whooping cough, or pertussis is a highly contagious respiratory disease. (smore.com)
- This contagious disease is more commonly known as whooping cough due the distinctive whoop that occurs when sufferers cough and gasp for breath. (go.com)
- Pertussis, also called whooping cough, is caused by Bordetella pertussis bacteria and is extremely contagious. (health-disease.org)
- Pertussis is most contagious in the early stage of the illness before the onset of the explosive coughing spell. (weau.com)
- The 30-second commercial by a pharmaceutical company encourages parents to get vaccinated against pertussis - a highly contagious respiratory disease also known as whooping cough. (utep.edu)
Known as whoo11
- Pertussis, also known as whooping cough, is a vaccine-preventable respiratory illness caused by the bacteria Bordetella pertussis . (tn.gov)
- Experts recommend that pregnant women receive the Tdap vaccine during their pregnancy in order to protect newborns from pertussis, also known as whooping cough. (medicalnewstoday.com)
- Modern vaccinations nearly wiped it out, but the stubborn disease, commonly known as whooping cough, has reemerged in recent years. (boston.com)
- Boren believed Brody had pertussis - commonly known as whooping cough, While doctors claimed it was unlikely due to the rarity of the disease, Borsen persevered - and doctors tested the child for it. (yahoo.com)
- But a combination of Andes' medical background (she's an assistant professor of global health at the Rollins School of Public Health at Emory University ) and a mother's intuition told her something else was tormenting her son - pertussis, also known as whooping cough. (ajc.com)
- Nearly twice as many cases of pertussis, commonly known as whooping cough, were reported in California during the first quarter this year compared to last year. (presstelegram.com)
- Residents in Lake County and surrounding areas are being alerted by health officials to an outbreak of pertussis, commonly known as whooping cough. (dailyherald.com)
- The 1,200 students in the Madison-Plains Local School District got an extra-long Thanksgiving break after officials confirmed 25 cases of pertussis, known as whooping cough. (dispatch.com)
- Despite high vaccine coverage in many developed countries, pertussis - otherwise known as whooping cough - has made a comeback in recent years. (consumeraffairs.com)
- WEAU) - The Clark County Health Department says there have been 12 confirmed cases of pertussis, also known as whooping cough, in the Thorp area. (weau.com)
- Clinical laboratory sciences professor Delfina C. Domínguez, Ph.D., (left) and chemistry assistant professor XiuJun (James) Li, Ph.D., (right) have collaborated to develop a low-cost, paper-based biochip to detect pertussis, also known as whooping cough, in medically underserved or low-resource settings. (utep.edu)
- Pertussis typically starts out with the symptoms of a mild cold with a runny nose, congestion, sneezing, cough and red, watery eyes. (courierpress.com)
- Symptoms of whooping cough generally include runny nose and a cough that gets worse and worse. (infoplease.com)
- At first, cold-like symptoms appear including runny nose, cough , sneezing, watery eyes, sore throat and raised a temperature. (netdoctor.co.uk)
- During the early stage of the disease, symptoms include runny nose, low-grade fever, and mild cough. (tn.gov)
- Initial symptoms of whooping cough may include runny nose, tiredness and mild fever. (brisbanetimes.com.au)
- Symptoms can vary by age, but children commonly suffer a cough and runny nose for one to two weeks, then the cough becomes more severe. (latimes.com)
- The first stage begins like a cold with a runny nose, sneezing, mild fever, and cough. (virginia.gov)
- Symptoms may resemble a mild cold, with runny nose, low-grade fever and an occasional cough. (labtestsonline.org)
- Initially, symptoms are usually similar to those of the common cold with a runny nose , fever , and mild cough . (wikipedia.org)
- The illness usually starts with mild respiratory symptoms include mild coughing, sneezing, or a runny nose . (wikipedia.org)
- At first, the disease may seem like a cold, and people tend to develop a runny nose, mild cough and low fever. (scientificamerican.com)
- The disease starts like the common cold, with a runny nose or congestion, sneezing, and sometimes a mild cough or fever. (massgeneral.org)
- Early symptoms are typically mild, like a cold, and can include runny nose, low fever, and mild cough. (cdc.gov)
- The first stage of whooping cough resembles the common cold, with a mild occasional cough, loss of appetite, runny nose and sneezing that lasts a week or 2. (mydr.com.au)
- Symptoms of B. pertussis at its onset are similar to the common cold, or an allergy attack with stuffy or runny nose, dry cough, loss of appetite, fatigue and, sometimes, a low fever. (nvic.org)
- The catarrhal stage can last one to two weeks and early symptoms include a runny nose, low-grade fever, a mild cough, and apnea . (healthmap.org)
- In the first stage of whooping cough, which may last 1 to 2 weeks, symptoms can resemble those of a common cold and include a runny or blocked nose, red and watery eyes, a dry cough (particularly at night), loss of appetite and tiredness. (mydr.com.au)
- Symptoms are similar to the common cold and include runny nose, sneezing, low grade fever and cough. (emaxhealth.com)
- Whooping cough, also known as pertussis, is a respiratory tract infection with a paroxysmal cough, caused by the bacterium Bordetella pertussis. (courierpress.com)
- A bacterium known as Bordetella pertussis causes whooping cough infection. (medicinenet.com)
- HealthDay News) -- Whooping cough is an infection of the respiratory system caused by the bacterium Bordetella pertussis , the Nemours Foundation says. (hon.ch)
- The Bordetella pertussis bacteria , which causes whooping cough and is passed through infected droplets in the air, has quite a long incubation period and symptoms only develop 6 to 20 days after infection,' says Dr Nadel. (netdoctor.co.uk)
- Whooping cough (pertussis) is an infection of the respiratory system caused by the bacterium Bordetella pertussis (or B. pertussis ). (kidshealth.org)
- An autopsy found that Dylan died of a massive infection of the bacterium Bordetella pertussis , which causes whooping cough. (baltimoresun.com)
- Pertussis, commonly called whooping cough, is a respiratory infection caused by the bacteria Bordetella pertussis . (labtestsonline.org)
- Whooping cough is caused by a strain of bacteria known as Bordetella pertussis, which infects the lining of the airways in the trachea (windpipe) and the bronchi, causing thick, sticky mucus to collect. (medic8.com)
- The main symptom of whooping cough is a severe cough followed by a whooping noise when you try to take a breath, but this does not usually appear until 2 weeks after infection with the Bordetella pertussis bacteria. (medic8.com)
- Whooping cough, also known as pertussis, is a disease caused by bacteria called Bordetella pertussis . (cdc.gov)
- Bordetella parapertussis , a relatively rare and antigenically distinct cousin of the pathogen B. pertussis , can present a clinical picture very similar to classical whooping cough. (medpagetoday.com)
- Whooping cough is caused by the bacterium Bordetella pertussis , although sometimes other bacteria can cause a pertussis-like syndrome. (mydr.com.au)
- The only sure way to find out if you or your child have B. pertussis or Bordetella parapertussis (or another respiratory disease caused by other viruses or bacteria), is to have a lab test that will positively confirm the exact organism causing the whooping cough symptoms. (nvic.org)
- 12 Bordetella parapertussis, another pertussis disease, can look identical to B, pertussis whooping cough, however symptoms are generally milder. (nvic.org)
- Caused by the bacteria Bordetella pertussis , the disease is transmitted person-to-person through coughing and sneezing and close contact with others . (healthmap.org)
- Commonly caused by Bordetella pertussis , its trademark symptom is severe coughing spells followed by a high-pitched "whoop" sound during inhalation. (fortherecordmag.com)
- 033.8, Whooping cough due to other specified organism, which also includes Bordetella bronchiseptica . (fortherecordmag.com)
- Whooping cough, caused by the bacteria Bordetella pertussis , is no longer a familiar condition to most Americans. (bu.edu)
- Whooping cough really refers to infections caused by the bacterium Bordetella pertussis, but an identical illness is produced by Bordetella parapertussis, Bordetella bronchiseptica and several types of adenovirus. (health-disease.org)
- Whooping cough is caused by the bacterium Bordetella pertussis Bordetella pertussis is also called B. pertussis. (health-disease.org)
- People are usually fine in between coughing spells. (medicinenet.com)
- You can spread it for up to 3 weeks after the coughing spells begin. (webmd.com)
- Violent coughing spells can end with vomiting. (infoplease.com)
- After about 7-10 days, the cough turns into " coughing spells" that end with a whooping sound as the person tries to breathe in air. (webmd.com)
- Because the cough is dry and doesn't produce mucus, these spells can last up to 1 minute. (webmd.com)
- Most people with whooping cough have coughing spells, but not everyone does. (webmd.com)
- Children under the age of 18 months with whooping cough should be watched at all times, because the coughing spells can make them stop breathing. (webmd.com)
- If your coughing spells are so bad that they keep you from drinking enough fluids, you risk dehydration . (webmd.com)
- can trigger coughing spells that can last more than a minute. (hon.ch)
- You may have choking spells or may cough so hard that you vomit. (medlineplus.gov)
- The infection causes coughing spells that are so severe that it can be hard to breathe, eat, or sleep. (nfid.org)
- Whooping cough causes coughing spells that can affect breathing, eating and sleeping. (nfid.org)
- Whooping cough causes severe coughing spells, which can sometimes end in a "whooping" sound when the child breathes in. (kidshealth.org)
- After about 1 to 2 weeks, the dry, irritating cough evolves into coughing spells. (kidshealth.org)
- Adults and teens may have milder or different symptoms, such as a prolonged cough (rather than coughing spells) or coughing without the whoop. (kidshealth.org)
- Many experts believe that antibiotics are most effective in shortening the length of the infection when they're given in the first stage of the illness, before coughing spells begin. (kidshealth.org)
- During these severe coughing spells, a person might vomit, or the lips or face may look blue from a lack of oxygen. (virginia.gov)
- Between coughing spells a person may appear well. (virginia.gov)
- The 'whoop' sound is caused by gasping for air between coughing spells. (hse.ie)
- Whooping cough is characterized by severe coughing spells that end in a "whooping" sound when the person breathes in. (sfgate.com)
- Caused by a bacterium, whooping cough is characterized by paroxysms (intense fits or spells) of coughing that end with the characteristic whoop as air is inhaled. (massgeneral.org)
- Symptoms include coughing spells that end with a "whooping" sound as air is breathed in. (massgeneral.org)
- The second stage is known as the paroxysmal stage due to the coughing spells. (mydr.com.au)
- Vomiting after a bout of coughing is common, and the persistent coughing spells can cause you to stop breathing temporarily. (mydr.com.au)
- The third stage of whooping cough is when the coughing spells starts to subside. (mydr.com.au)
- With whooping cough disease, it is possible to have such violent coughing spells, especially at night, that large amounts of mucous are vomited up through the mouth and nose and interfere with breathing. (nvic.org)
- These coughing spells may produce plenty of mucus and the cough may finish with a loud whoop. (mydr.com.au)
- The persistent coughing spells can cause a child to stop breathing temporarily. (mydr.com.au)
- Through mechanisms that are still poorly understood, pertussis toxin provokes violent coughing spells, while evading our immune responses. (bu.edu)
- Gagging or vomiting may occur after severe coughing spells. (health-disease.org)
- Older children and adults may not have a 'whoop', but will have coughing spells. (mydr.com.au)
- Sudden, uncontrollable fits or spells of coughing. (emaxhealth.com)
- Gagging or vomiting after the coughing spells. (emaxhealth.com)
- The illness progresses to spells of explosive coughing that can interrupt breathing, eating, and sleeping, and is commonly followed by vomiting and exhaustion. (weau.com)
- The severe coughing spells can last for several weeks to two months or longer. (weau.com)
- However, infant deaths and a widespread whooping cough outbreak led to California becoming the first state to recommend the routine administration of Tdap during pregnancy in 2010. (medicalnewstoday.com)
- As mentioned earlier, whooping cough has made a comeback in states like California, most notably in the San Diego area . (inquisitr.com)
- In fact, CBS News reported that, "researchers have linked parents not vaccinating their children for who0ping cough to outbreaks of the disease that occurred in 2010 in California. (inquisitr.com)
- (CNN) -- Whooping cough, also known as pertussis, has claimed the 10th victim in California, in what health officials are calling the worst outbreak in 60 years. (cnn.com)
- The death of Bianchi's son highlights one of the chief problems confronting California health officials trying to stem a current upswing in the disease: Whooping cough is easily misdiagnosed, especially in its early stages. (baltimoresun.com)
- Four newborns, all younger than 3 months, have died in California so far this year, an alarming number to health officials because it already exceeds last year's total of whooping cough-related deaths, three. (baltimoresun.com)
- AN OUTBREAK of whooping cough in California could be the worst in 50 years, the state's Department of Public Health said last week. (newscientist.com)
- Tartof, who is from Southern California Permanente Medical Group in Pasadena, and her team used immunization records and state-wide whooping cough data to track more than 400,000 children in the states of Minnesota and Oregon. (foxnews.com)
- The whooping cough vaccine isn't perfect, but public health officials suspected that something else contributed to the 2010 pertussis outbreak in California. (npr.org)
- In 2010, a whooping cough outbreak in California sickened 9,120 people, more than in any year since 1947. (npr.org)
- Joanne Faryon of KPBS in San Diego reports on the resurgence of whooping cough in California after decades of the disease's decline. (pbs.org)
- For those stations not taking a pledge break, we have a report on the resurgence of whooping cough in California. (pbs.org)
- Whooping cough was nearly wiped out by the late 1970s because of mass immunization, but it somehow found its way back to California and other highly vaccinated communities around the world. (pbs.org)
- The bacteria that cause whooping cough (shown above in green) lodge themselves in the small hair-like structures of your airways. (webmd.com)
- If a person with whooping cough sneezes, laughs, or coughs, small droplets that contain the bacteria may fly through the air. (webmd.com)
- The bacteria cause swelling and inflammation , which lead to a dry, long-lasting cough and other cold-like symptoms. (webmd.com)
- Most people acquire the bacteria by breathing in the bacteria that are present in droplets released when an infected person coughs or sneezes. (medicinenet.com)
- The pertussis bacteria also infect the windpipe, where they bring on a persistent, violent cough. (babycenter.com)
- But after scientists discovered that the pertussis bacteria caused the awful respiratory disease, with its characteristic "whoop" sound, researchers produced an enormously effective vaccine. (governing.com)
- The bacteria is spread in tiny droplets when an infected person coughs or sneezes. (cnn.com)
- These bacteria spread through the air in droplets produced by sneezing and/or coughing. (virginia.gov)
- The vaccine stimulates your immune system to produce high levels of antibodies to the whooping cough bacteria. (hse.ie)
- If you or your baby are in contact with whooping cough the antibodies will attack these bacteria and will protect you and your baby from whooping cough. (hse.ie)
- it doesn't contain whole cells of the whooping cough bacteria as the old vaccine did. (abc.net.au)
- People with whooping cough can spread the bacteria to others when they cough, sneeze, or share the same breathing space. (cdc.gov)
- If your child has never had the disease and has not been vaccinated against it, they are likely to get whooping cough if they come into contact with the bacteria. (mydr.com.au)
- When an infected person coughs or sneezes, microscopic, bacteria-laden droplets can easily be inhaled by anyone nearby. (thedoctorstv.com)
- The bacteria causes inflammation, constricting the airways and leading to the distinctive gasping in between coughs. (thedoctorstv.com)
- The bacteria are passed from person to person by the infected mucus during coughing or sneezing. (mydr.com.au)
- The symptoms of whooping cough commonly develop about 7 to 10 days after exposure to the bacteria, but can occur any time from a few days to a few weeks. (mydr.com.au)
- Pertussis is spread by coughing and sneezing while in close contact with others, who then breathe in the pertussis bacteria. (smore.com)
- Whooping cough (pertussis) is a highly infectious disease caused by bacteria. (mydr.com.au)
- The bacteria are spread by contact with the respiratory droplets from an infected person through coughing. (weau.com)
- Whooping cough can lead to complications that can be life-threatening, especially in babies. (webmd.com)
- Whooping cough can cause serious and sometimes deadly complications in babies and young children. (cdc.gov)
- If your child gets whooping cough and they have not been vaccinated, they are more likely to develop complications such as pneumonia . (mydr.com.au)
- While it tends to be less severe in adolescents and adults, complications due to persistent coughing are common. (mydr.com.au)
- Some patients may experience complications from whooping cough, and most are caused by the strenuous coughing. (fortherecordmag.com)
- With proper care, most teenagers and adults recover from whooping cough without complications. (health-disease.org)
- Complications that can develop from whooping cough include pneumonia and middle ear infections, which require treatment with antibiotics. (mydr.com.au)
- Unvaccinated children are much more likely to develop complications if they do get whooping cough. (mydr.com.au)
- Complications of whooping cough include bacterial pneumonia, rib fractures and even death. (emaxhealth.com)
- After a week or two, the cough may worsen and progress into classic pertussis with fits of frequent, rapid cough following by a high-pitched 'whoop' caused by inspired air going through a partially closed airway. (courierpress.com)
- The term "whooping cough" is based on the characteristic noise made as the person at the end of a coughing attack that sounds like a high-pitched "whoop" as the person tries to suck in a breath. (medicinenet.com)
- Following a fit of coughing, a high-pitched whoop sound or gasp may occur as the person breathes in. (wikipedia.org)
- After one to two weeks, the coughing classically develops into uncontrollable fits, followed by a high-pitched "whoop" sound in younger children, or a gasping sound in older children, as the person tries to inhale ( paroxysmal stage). (wikipedia.org)
- Later symptoms of the disease may include "fits" of many rapid coughs followed by a high-pitched "whoop," vomiting, and exhaustion. (cdc.gov)
- The first symptoms are similar to those of a common cold but the cough becomes severe and often progresses to spasms that can result in vomiting or the high-pitched "whoop" sound. (dailyherald.com)
- The disease causes coughing attacks that can end in a high-pitched whooping sound. (mydr.com.au)
- In advanced stages, thick mucous develops in the lungs and clogs air passages, triggering violent episodes of coughing, choking and vomiting up of mucus followed by a high-pitched intake of breath that sounds like 'whoop. (nvic.org)
- The disease causes sudden attacks of an irritating cough that often end in a high-pitched whooping sound as the child takes a breath. (mydr.com.au)
- In the more advanced stages, it's marked by the symptom that gives the disease its name: a severe, hacking cough followed by a high-pitched intake of breath that sounds like "whoop. (health-disease.org)
- A "whoop" which is a high pitched noise heard when breathing in and after a cough spasm. (emaxhealth.com)
Symptoms of whoop4
Outbreak of whoop5
- Yesterday's lie came from Dr Mitchell Smith, New South Wales Health Department mouthpiece, who said that the outbreak of whooping cough was firstly a reflection of low immunisation rates in parts of New South Wales, and second, that vaccine antibodies wane with time. (whale.to)
- There is an outbreak of whooping cough where I live. (babycenter.com)
- An outbreak of whooping cough, or pertussis, at a Florida preschool in which nearly all the students had been fully vaccinated against the disease, raises new concerns about the vaccine's effectiveness, a new report suggests. (scientificamerican.com)
- A private school in El Sobrante is closed today because of an outbreak of whooping cough that has affected at least 16 students, authorities said. (sfgate.com)
- The outbreak of whooping cough that closed an entire central Ohio school district last week should convince parents to immunize their children against deadly and dreaded diseases that once were widespread and could become so again. (dispatch.com)
- It is possible for older children and adults to have a prolonged cough, no real whoop, but in many cases there can be a significant and violent cough that interferes with lifestyle. (medicinenet.com)
- Sometimes adults with the condition just have a cough that won't go away. (webmd.com)
- Adults may develop whooping cough as their immunity from vaccines wears off over time. (medicinenet.com)
- While pertussis is rarely deadly for otherwise healthy adults, struggling through the aptly named "100-day cough" isn't particularly pleasant, with its uncontrollable fits of violent coughing around the clock. (livescience.com)
- Although adults can also catch whooping cough , they tend to have mild symptoms. (netdoctor.co.uk)
- Their immunity will gradually wane as they grow up, and some vaccinated adults have caught whooping cough. (netdoctor.co.uk)
- CDC recommends that adults and adolescents receive one dose of a tetanus-diphtheria-pertussis (Tdap) booster vaccine to protect against whooping cough, as a substitute for the Td (tetanus-diphtheria) booster recommended every 10 years. (nfid.org)
- In older children and adults with whooping cough, the symptoms are often far milder and the condition is often not diagnosed. (netdoctor.co.uk)
- According to the National Institutes of Health, 'the whoop noise is rare in patients under 6 months and in adults. (cnn.com)
- Adults usually don't have the 'whoop' cough, so they may not think they have pertussis. (cnn.com)
- She also diverted federal funding for immunizations to purchase an additional 27,000 whooping cough vaccines for adults who are unable to acquire them on their own. (governing.com)
- Adults are also at risk for pneumonia and rib fractures caused by coughing. (go.com)
- It can take up to three months for an individual to recover from whooping cough and symptoms are usually much more severe in young children than adults. (medic8.com)
- Not all children get the 'whoop' and often older children and adults just have a cough. (hse.ie)
- In adults, antibiotics are given to pregnant women within 6 weeks of the beginning of the cough. (massgeneral.org)
- This means more adults are now susceptible to whooping cough after the vaccine has worn off. (massgeneral.org)
- For adults, the only real symptom can be coughing. (presstelegram.com)
- In adults, pertussis may appear as a persistent cough. (eastbayexpress.com)
- However, in adolescents and adults, or children who have been vaccinated, the disease is often milder and people may even not show any symptoms, or they may have mild or persistent cough. (mydr.com.au)
- However, many people (especially older children and adults) do not make the typical 'whoop' sound. (mydr.com.au)
- Adults and adolescents with whooping cough may have milder symptoms, such as a persistent, mucous-producing cough that goes on for 4-8 weeks. (nvic.org)
- Often older children and adults do not make the whooping cough when they cough. (nvic.org)
- Symptoms of pertussis are sometimes milder in those who have had one or more doses of pertussis containing vaccines (DPT, DTaP, Tdap) 10 and doctors or nurses may not suspect B. pertussis whooping cough in vaccinated children, adolescents and adults, who present with a bad cough. (nvic.org)
- Whooping cough is also dangerous in elderly people, but tends to be less severe in adolescents and adults. (mydr.com.au)
- In our office, we have seen quite a few children and adults with long hard coughs as we always do this time of year. (whale.to)
- Again, very few coughing children and adults really have pertussis. (whale.to)
- For adults, whooping cough may only be a nuisance. (pbs.org)
- In older children, adolescents and adults the symptoms are usually milder and without the typical whoop. (weau.com)
- Td is the name of the booster for adults, and differs from the primary dose in that it does not include immunization against pertussis (whooping cough). (wikipedia.org)
- Pertussis is known for uncontrollable, violent coughing which often makes it hard to breathe. (cdc.gov)
- Whooping cough is an infectious bacterial disease that causes uncontrollable coughing. (medlineplus.gov)
- Whooping cough causes a very severe, uncontrollable cough and can be passed from person to person very quickly. (medic8.com)
- A violent cough, with bouts of uncontrollable episodes of coughing. (medic8.com)
- The malady causes an "uncontrollable, violent coughing which often makes it hard to breathe. (villagevoice.com)
- 1 The major symptom of B. pertussis whooping cough disease is uncontrollable coughing. (nvic.org)
- Stay up to date on studies that support the safe and effective use of the Tdap vaccine in pregnant women and other strategies to prevent whooping cough in babies. (cdc.gov)
- But it wasn't until the late 1940s, scientists developed a vaccine effective enough to prevent whooping cough. (pbs.org)
- Fortunately, a vaccine is available to prevent whooping cough. (emaxhealth.com)
- Once the whooping stage begins, antibiotics don't work. (infoplease.com)
- If doctors diagnose whooping cough early on, antibiotics can help cut down coughing and other symptoms. (webmd.com)
- If you have whooping cough, treatment with antibiotics may help if given early. (medlineplus.gov)
- Of course, if the cough gets worse even with antibiotics, call your doctor immediately. (babycenter.com)
- Whooping cough can be treated successfully with antibiotics and most people make a full recovery. (netdoctor.co.uk)
- If you catch whooping cough but don't take antibiotics, you can infect others for three weeks after your 'whooping' coughing attacks commence. (netdoctor.co.uk)
- Whooping cough is treated with antibiotics. (kidshealth.org)
- Whooping cough can usually be treated very effectively with antibiotics and the vast majority of people make a full recovery. (medic8.com)
- Evidence to support interventions for the cough, other than antibiotics, is poor. (wikipedia.org)
- Emma revealed last week that she was hospitalised while filming The Crown's fourth series after being ill with a cough while on location in Spain, after stopping to pick up some antibiotics. (dailymail.co.uk)
- Antibiotics may help reduce whooping cough symptoms if given early enough, and they can help stop the spread of the disease. (mydr.com.au)
- People are infectious for 3 weeks after the onset of cough, or until they have completed 5 days of appropriate antibiotics. (mydr.com.au)
- Whooping Cough or pertussis is usually treated with antibiotics, however, if it is more severe, then it may require treatment in the hospital. (smore.com)
- Doctors treat whooping cough with antibiotics. (bu.edu)
- Caused by the Bordatella pertussis bacterium, pertussis sometimes is called the 100-day cough due to the prolonged illness it can cause. (upi.com)
- It's used to estimate antibody levels directed against a toxin produced by the bacterium and is suitable for assisting in the diagnosis of those patients who have been coughing for more than two weeks and are suspected of having whooping cough. (netdoctor.co.uk)
- Much of the illness around right now and being reported as whooping cough may be caused by a related bacterium called B. Parapertussis. (whale.to)
- The bacterium that causes whooping cough was first isolated in Belgium in 1906. (pbs.org)
- The bacterium that causes whooping cough started to look a little different. (pbs.org)
- If a cough has lasted more than seven days or has become violent in nature, that person may have pertussis and should be checked. (medicinenet.com)
- There can be anywhere from a 1 to 6-week stage called the paroxysmal stage that is characterized by violent paroxysmal cough, often with a characteristic whoop. (medicinenet.com)
- Initial symptoms are very similar to a cold, but a week or two later, a violent cough develops. (cnn.com)
- Violent coughing can cause the pleura to rupture, leading to a pneumothorax . (wikipedia.org)
- Coughing fits are often violent and the cough may finish with a loud 'whoop' sound when you breathe in. (mydr.com.au)
- It can cause violent and rapid coughing, over and over, until the air is gone from the lungs and you are forced to inhale with a loud 'whooping' sound. (smore.com)
- Named after the symptoms, 'paroxysm,' or violent coughing fit. (smore.com)
- At first, it can mimic a cold, but later produces a violent and persistent cough, a cough that leaves children gasping for air creating that distinct whooping sound. (pbs.org)
- Don't use over-the-counter cough medicines, cough suppressants , or expectorants (medicines that make you cough up mucus) to treat whooping cough. (webmd.com)
- The body then tries to dislodge and get rid of this mucus by coughing. (medic8.com)
- Mucus will begin to accumulate in the airways and after a week or two, the signature severe, hacking cough will develop. (thedoctorstv.com)
- The inflamed airways produce more mucus which then causes the irritating cough. (mydr.com.au)
- The symptoms start to worsen after one to two weeks and progress to include an uncontrolled and prolonged cough caused by the accumulation of thick mucus. (fortherecordmag.com)
- In the second stage of whooping cough, which may last 6 weeks or more, symptoms worsen, with severe coughing attacks that may bring up thick mucus. (mydr.com.au)
- Whooping cough got its name from the whooping sound children make when they try to breathe after a coughing spell. (infoplease.com)
- Rapid fits of coughing for 20 or 30 seconds nonstop, followed by a "whoop" sound as they struggle to breathe before the next coughing spell starts. (babycenter.com)
- A hacking cough is sometimes followed by silence and then the 'whoop' as the baby fights to breathe in. (netdoctor.co.uk)
- To the editor: Any parents not vaccinating their children should be forced to watch a video of an infant with pertussis struggling to breathe and cough. (latimes.com)
- This causes a "whooping" noise as they attempt to breathe after a coughing fit. (latimes.com)
- The cough makes it difficult to breathe and patients often make a "whooping'' noise as they gasp for air, giving the disease its nickname. (boston.com)
- This is a baby boy struggling to breathe and turning blue with every cough. (yahoo.com)
- Whooping cough also makes it difficult to breathe, as the airways become inflamed and this causes the whooping sound after coughing. (medic8.com)
- Whooping cough causes long bouts of coughing and choking making it hard to breathe. (hse.ie)
- Children less than one year old may have little or no cough and instead have periods where they do not breathe . (wikipedia.org)
- It used to be called 'The 100-Day Cough,' but if a baby gets it, they cough so hard, they can't breathe, and it can be fatal. (thedoctorstv.com)
- Later symptoms include the gradual onset of coughing, which develops into fits of rapid coughs, sometimes with a classic inspiratory whoop as the patient gasps for air, and sometimes with post-coughing vomiting and exhaustion. (tn.gov)
- But a week or two later, an infected person may develop fits of rapid coughs followed by a loud 'whooping' sound. (scientificamerican.com)
- The disease then progresses to the paroxysmal stage, which can last one to six weeks, and often consists of numerous and rapid coughs with the classic 'whoop' sound . (healthmap.org)
- A century ago, whooping cough spread dread across the country, causing more than 5,000 deaths a year. (governing.com)
- The trend alarms officials because whooping cough, formally known as pertussis, was once a devastating disease in the United States, infecting as many as 270,000 people each year and causing 10,000 deaths, prior to the introduction of a vaccine in the 1940s. (upi.com)
- The World Health Organization reported more than 200,000 whooping cough deaths in 2000 world-wide. (go.com)
- Whooping cough caused thousands of deaths in the 1930s and 1940s. (massgeneral.org)
- there have been two infant deaths this year as a result of whooping cough. (eastbayexpress.com)
- No deaths due to whooping cough have been reported. (emaxhealth.com)
- By the 1970s, through vaccinations, whooping cough was as endangered as the whooping crane, with only about 0.000005 percent of the population infected. (livescience.com)
- Most children receive several vaccinations against whooping cough (pertussis) as part of the DTaP series , which also protects against diphtheria and tetanus. (babycenter.com)
- Later, at age 11 or 12, your child will get an additional dose of whooping cough protection as part of the TdaP vaccine. (babycenter.com)
- When the Tdap vaccine was first licensed in 2005, it was advised to be given after birth due to fears that newborns could inadvertently receive whooping cough from it. (medicalnewstoday.com)
- And then you're getting the Tdap shot which includes the whooping cough. (pbs.org)
Case of whoop5
- The announcement was prompted by a confirmation of at least one case of whooping cough in a Flambeau student. (weau.com)
- The Cardinal School District in Eldon also reports a case of whooping cough at the high school. (radioiowa.com)
- Dr. Granville states, "without presumption," that in almost every case of whooping-cough this medicine, given early, removes the disease (p. 64), and Dr. Hamilton Roe, in a special treatise (1838), records equally excellent results. (chestofbooks.com)
- A severe case of whooping cough or pneumonia in a young child could result in seizures, brain damage or death. (mydr.com.au)
- Last year, Morrow County reported just one case of whooping cough, a 16-year-old. (seattlepi.com)
Child has whoop2
Vaccine for whoop2
Protection against whoop2
- Protection against whooping cough starts to weaken a few years after preschool children get their final shot, according to a U.S. study, meaning that some children may be at risk of developing the disease before they can get a booster shot. (foxnews.com)
- However, children who get DT will not receive any protection against whooping cough. (cdc.gov)
- Earlier in the year, a study in the UK reported that around 20% of children aged 5-15 visiting their doctor with a persistent cough have whooping cough , despite nearly all children being fully vaccinated for the disease. (medicalnewstoday.com)
- The disease may present as a persistent cough rather than typical pertussis. (virginia.gov)
- Whooping cough is spread through the air, making it particularly infectious. (infoplease.com)
- The news that Ebola may have been allowed into Washington, DC and that a case of deadly whooping cough has been diagnosed in a DC suburb* would have been enough to shake any normal American government into following our existing health and infectious disease laws for all immigrants and visitors to the U.S. and closing our county s borders. (freerepublic.com)
- Whooping cough is infectious from the first sneezes and throughout the course of the disease, which can last for up to eight weeks. (netdoctor.co.uk)
- Whooping cough is highly infectious and can be passed from one person to another very quickly and easily through droplets, which are expelled when you cough or sneeze. (medic8.com)
- People are infectious from the start of symptoms until about three weeks into the coughing fits. (wikipedia.org)
- During a 5-month period between September 2013 and January 2014, 26 preschoolers, two staff members and 11 family members of the students or staff at the facility in Leon County came down with whooping cough , according to a report of the outbreak published today (Jan. 13) in the journal Emerging Infectious Diseases. (scientificamerican.com)
- Parents of Kids with Infectious Diseases has audio of "whooping cough. (nwahomepage.com)
- If you have whooping cough you are infectious from 7 days after being exposed to the illness, and up until 3 weeks after severe coughing attacks began. (mydr.com.au)
- The diagnosis is usually made from the symptoms and the history of contact with a person suffering from whooping cough. (netdoctor.co.uk)
- If your doctor suspects whooping cough because of the classic cough symptoms, they may take a swab to make sure of the diagnosis. (mydr.com.au)
- Pneumonia associated with whooping cough is classified as code 484.3, Pneumonia in whooping cough, sequenced as the secondary diagnosis. (fortherecordmag.com)
- The diagnosis was whooping cough. (pbs.org)
Outbreaks of whoop2
- Physicians described the first outbreaks of whooping cough in the 16th century. (medicinenet.com)
- This may partly explain recent outbreaks of whooping cough among the highly vaccinated U.S. population, in which 95 percent of children have received at least five doses of pertussis vaccine between two months and six years old. (mercola.com)
- However, you're much less likely to get whooping cough if you've been vaccinated, and if you do catch it the symptoms are normally milder. (babycenter.com)
- An important thing to remember is the kids who do receive all five doses on time generally have milder (whooping cough) than those who are under-vaccinated or unvaccinated,' Tartof told Reuters Health. (foxnews.com)
- Children who have been vaccinated can still get whooping cough but it will usually be much milder than for a child who has not been vaccinated. (mydr.com.au)
- The pertussis vaccine, called DTaP (diphtheria, tetanus, and pertussis) has been responsible for a dramatic drop in whooping cough in recent decades. (forbes.com)
- Whooping cough can be prevented with the pertussis vaccine , which is part of the DTaP (diphtheria, tetanus, acellular pertussis) immunization . (kidshealth.org)
- This is a low dose tetanus (T), diphtheria (d) and low dose pertussis (ap) booster vaccine which protests against tetanus, diphtheria and whooping cough (pertussis). (hse.ie)
- Mine was 3 in 1 - whooping cough, diphtheria & tetanus - & apparently I've had them all as a child anyway, which I think may have helped. (netmums.com)
- The vaccine is contained in two different combination products both of which protect against diphtheria, tetanus and pertussis (whooping cough). (emaxhealth.com)
- After 1 to 2 weeks, those symptoms give way to intense bouts of coughing. (webmd.com)
- After this, one to two weeks later, the typical coughing bouts set in. (netdoctor.co.uk)
- Coughing bouts may develop followed by a big, deep gasp, then often vomiting. (brisbanetimes.com.au)
- Usually bouts of coughing last between 1 and 2 minutes, but episodes usually follow on from one another and some people can experience more than 15 bouts of coughing per day. (medic8.com)
- the characteristic bursts of coughing appear in the second, or paroxysmal, stage. (medicinenet.com)
- These may last for a week or two before onset of the more severe 'paroxysmal' stage, when your child coughs up thick phlegm making a 'whoop' sound with each sharp intake of breath. (netdoctor.co.uk)
- The classic symptoms of pertussis are a paroxysmal cough, inspiratory whoop, and fainting , or vomiting after coughing. (wikipedia.org)
- The absence of a paroxysmal cough or posttussive emesis , though, makes it almost half as likely. (wikipedia.org)
- After cough fits, someone with pertussis often needs to take deep breaths, which result in a "whooping" sound. (cdc.gov)
- The tell-tale whooping sound when children gasp for breath is becoming more familiar in the UK as whooping cough makes a comeback. (netdoctor.co.uk)
- The classic symptom is a "whoop," the sound of someone gasping for breath during a bad coughing spell. (nfid.org)
- At the end of a spell, the child may make the characteristic whooping sound when breathing in or may vomit. (kidshealth.org)
- It can cause them to turn blue from lack of oxygen, due to seemingly unending coughing fits, which result in a whooping kind of sound as they gasp for breath. (upi.com)
- A pediatrician checking Dylan heard Bianchi's bark-like cough - and a subsequent whooping sound as she gasped for air. (baltimoresun.com)
- Coughing is frequently followed by a 'whoop' sound and patients may feel exhausted and/or vomit after these coughing fits. (labtestsonline.org)
- A whooping sound, which occurs when you take a sharp intake of breath after coughing. (medic8.com)
- 6 Click here to hear what whooping cough can sound like. (nvic.org)
- According to the Mayo Clinic, prolonged coughing attacks can induce vomiting, cause extreme fatigue, result in a red or blue face, and will usually end with a "whoop" or gasping sound during the next breath. (thedoctorstv.com)
- It's called "whooping cough" because that's the sound a person makes while coughing. (nwahomepage.com)
- The main symptoms are severe coughing fits accompanied by a "whoop" sound as a child gasps for breath. (bbc.com)
- Health officials have declared a whooping cough outbreak at Moncton High School. (cbc.ca)
- In May, Washington state public health officials declared a health emergency as whooping cough galloped across the state. (governing.com)
- In response to the current whooping cough resurgence, state health officials are urging more people to get booster shots. (boston.com)
- The school has an "unusually high number of children" who have not been vaccinated against whooping cough, which is also known as pertussis, health officials said. (sfgate.com)
- Whooping cough, or pertussis, often strikes teenagers first but a 4-month-old Morrow County infant recently had to be hospitalized, health officials said. (seattlepi.com)
- Health officials in Western North Carolina are treating a large number of patients with whooping cough (also called pertussis). (emaxhealth.com)
- Bianchi encountered a variety of doctors and medical personnel in the latter days of her pregnancy - when she'd already developed a cough. (baltimoresun.com)
- The best time to get the whooping cough vaccine is between 16-36 weeks of your pregnancy to give your baby the best protection. (hse.ie)
- The CDC recommends that pregnant women get a whooping cough vaccine in the third trimester of every pregnancy. (massgeneral.org)
- In Great Britain, immunization rates for whooping cough dropped from over 80 percent to 33 percent (and in some regions to less than 10 percent) from 1974 to 1977. (livescience.com)
- In the past, whooping cough was largely controlled by infant and childhood immunization. (nfid.org)
- Of the 621 people who got whooping so far this year, 527 were up-to-date, 67 were not, and the immunization status was unknown for 27. (kpbs.org)
- Is Whooping Cough Pertussis Vaccine Effective or Not? (mercola.com)
- Nearly a century after the release of the whooping cough (B. pertussis) vaccine , mounting evidence suggests that widespread mandated use of the vaccine could potentially be doing more harm than good in the long term-in addition to having been found lacking in the effectiveness department. (mercola.com)
- Both B. pertussis whooping cough and the pertussis vaccine carry risks. (nvic.org)
Incidence of whoop1
- Within the next few years, the incidence of whooping cough started rising again, a pattern that has been repeated in several other counties-including England, Canada, Australia, Ireland, and Spain-that made the same switch. (bu.edu)
Recover from whoop1
- The star, who plays young Princess Diana, explained that the early end to filming finally gave her a chance to recover from whooping cough, which she battled throughout the production. (dailymail.co.uk)