Borna disease virus: A species in the genus Bornavirus, family BORNAVIRIDAE, causing a rare and usually fatal encephalitic disease in horses and other domestic animals and possibly deer. Its name derives from the city in Saxony where the condition was first described in 1894, but the disease occurs in Europe, N. Africa, and the Near East.Borna Disease: An encephalomyelitis of horses, sheep and cattle caused by BORNA DISEASE VIRUS.Newcastle disease virus: The most well known avian paramyxovirus in the genus AVULAVIRUS and the cause of a highly infectious pneumoencephalitis in fowl. It is also reported to cause CONJUNCTIVITIS in humans. Transmission is by droplet inhalation or ingestion of contaminated water or food.Viruses, Unclassified: Viruses whose taxonomic relationships have not been established.Foot-and-Mouth Disease Virus: The type species of APHTHOVIRUS, causing FOOT-AND-MOUTH DISEASE in cloven-hoofed animals. Several different serotypes exist.Rats, Inbred LewViral Proteins: Proteins found in any species of virus.RNA, Viral: Ribonucleic acid that makes up the genetic material of viruses.Mononegavirales: An order comprising four families of eukaryotic viruses possessing linear, non-segmented, negative-strand RNA genomes. The families are BORNAVIRIDAE; FILOVIRIDAE; PARAMYXOVIRIDAE; and RHABDOVIRIDAE.Virus Replication: The process of intracellular viral multiplication, consisting of the synthesis of PROTEINS; NUCLEIC ACIDS; and sometimes LIPIDS, and their assembly into a new infectious particle.Antibodies, Viral: Immunoglobulins produced in response to VIRAL ANTIGENS.Infectious bursal disease virus: A species of AVIBIRNAVIRUS causing severe inflammation of the bursa of Fabricius in chickens and other fowl. Transmission is thought to be through contaminated feed or water. Vaccines have been used with varying degrees of success.Antigens, Viral: Substances elaborated by viruses that have antigenic activity.Vero Cells: A CELL LINE derived from the kidney of the African green (vervet) monkey, (CERCOPITHECUS AETHIOPS) used primarily in virus replication studies and plaque assays.Bornaviridae: A family in the order MONONEGAVIRALES comprising one genus Bornavirus. This family has a unique form of mRNA processing: replication and transcription takes place in the nucleus.LiechtensteinNucleoproteins: Proteins conjugated with nucleic acids.Cercopithecus aethiops: A species of CERCOPITHECUS containing three subspecies: C. tantalus, C. pygerythrus, and C. sabeus. They are found in the forests and savannah of Africa. The African green monkey (C. pygerythrus) is the natural host of SIMIAN IMMUNODEFICIENCY VIRUS and is used in AIDS research.Aphthovirus: A genus of the family PICORNAVIRIDAE infecting mainly cloven-hoofed animals. They cause vesicular lesions and upper respiratory tract infections. FOOT AND MOUTH DISEASE VIRUS is the type species.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Parapoxvirus: A genus of the family POXVIRIDAE, subfamily CHORDOPOXVIRINAE, which infect ungulates and may infect humans. ORF VIRUS is the type species.Cell Line: Established cell cultures that have the potential to propagate indefinitely.Horses: Large, hoofed mammals of the family EQUIDAE. Horses are active day and night with most of the day spent seeking and consuming food. Feeding peaks occur in the early morning and late afternoon, and there are several daily periods of rest.RNA Viruses: Viruses whose genetic material is RNA.Horse Diseases: Diseases of domestic and wild horses of the species Equus caballus.Foot-and-Mouth DiseaseViral Structural Proteins: Viral proteins that are components of the mature assembled VIRUS PARTICLES. They may include nucleocapsid core proteins (gag proteins), enzymes packaged within the virus particle (pol proteins), and membrane components (env proteins). These do not include the proteins encoded in the VIRAL GENOME that are produced in infected cells but which are not packaged in the mature virus particle,i.e. the so called non-structural proteins (VIRAL NONSTRUCTURAL PROTEINS).Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.Vaccinia virus: The type species of ORTHOPOXVIRUS, related to COWPOX VIRUS, but whose true origin is unknown. It has been used as a live vaccine against SMALLPOX. It is also used as a vector for inserting foreign DNA into animals. Rabbitpox virus is a subspecies of VACCINIA VIRUS.Gene Expression Regulation, Viral: Any of the processes by which cytoplasmic factors influence the differential control of gene action in viruses.Genome, Viral: The complete genetic complement contained in a DNA or RNA molecule in a virus.Newcastle Disease: An acute febrile, contagious, viral disease of birds caused by an AVULAVIRUS called NEWCASTLE DISEASE VIRUS. It is characterized by respiratory and nervous symptoms in fowl and is transmissible to man causing a severe, but transient conjunctivitis.Virus Cultivation: Process of growing viruses in live animals, plants, or cultured cells.Receptors, Virus: Specific molecular components of the cell capable of recognizing and interacting with a virus, and which, after binding it, are capable of generating some signal that initiates the chain of events leading to the biological response.Hemorrhagic Disease Virus, Rabbit: A species in the genus LAGOVIRUS which causes hemorrhagic disease, including hemorrhagic septicemia, in rabbits.Virus Shedding: The expelling of virus particles from the body. Important routes include the respiratory tract, genital tract, and intestinal tract. Virus shedding is an important means of vertical transmission (INFECTIOUS DISEASE TRANSMISSION, VERTICAL).Open Reading Frames: A sequence of successive nucleotide triplets that are read as CODONS specifying AMINO ACIDS and begin with an INITIATOR CODON and end with a stop codon (CODON, TERMINATOR).Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Marek Disease: A transmissible viral disease of birds caused by avian herpesvirus 2 (HERPESVIRUS 2, GALLID) and other MARDIVIRUS. There is lymphoid cell infiltration or lymphomatous tumor formation in the peripheral nerves and gonads, but may also involve visceral organs, skin, muscle, and the eye.Virus Diseases: A general term for diseases produced by viruses.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Virus Assembly: The assembly of VIRAL STRUCTURAL PROTEINS and nucleic acid (VIRAL DNA or VIRAL RNA) to form a VIRUS PARTICLE.Lung: Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.Interferons: Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions.Rabbits: The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.Interferon Type I: Interferon secreted by leukocytes, fibroblasts, or lymphoblasts in response to viruses or interferon inducers other than mitogens, antigens, or allo-antigens. They include alpha- and beta-interferons (INTERFERON-ALPHA and INTERFERON-BETA).GermanySpatio-Temporal Analysis: Techniques which study entities using their topological, geometric, or geographic properties and include the dimension of time in the analysis.Sciuridae: A family of the order Rodentia which contains 49 genera. Some of the more common genera are MARMOTA, which includes the marmot and woodchuck; Sciurus, the gray squirrel, S. carolinensis, and the fox squirrel, S. niger; Tamias, the eastern and western chipmunk; and Tamiasciurus, the red squirrel. The flying squirrels, except the scaly-tailed Anomaluridae, also belong to this family.Proventriculus: A thin-walled, glandular stomach found in birds. It precedes the gizzard.Mononegavirales Infections: Infections with viruses of the order MONONEGAVIRALES. The concept includes FILOVIRIDAE INFECTIONS; PARAMYXOVIRIDAE INFECTIONS; and RHABDOVIRIDAE INFECTIONS.New England: The geographic area of New England in general and when the specific state or states are not indicated. States usually included in this region are Maine, New Hampshire, Vermont, Massachusetts, Connecticut, and Rhode Island.
"Modulation of miR-122 on persistently Borna disease virus infected human oligodendroglial cells". Antiviral Res. 87 (2): 249-56 ... other RNA viruses and viral mimetics (e.g. poly(I:C)). Recent studies have shown that replication of hepatitis C virus (HCV) is ... Jangra RK, Yi M, Lemon SM (2010). "Regulation of hepatitis C virus translation and infectious virus production by the microRNA ... Biomarkers in Liver Disease. V. B. Patel and V. R. Preedy. Dordrecht, Springer Netherlands: ISBN 978-94-007-7675-3, page 193- ...
In general these viruses show only about 65% sequence identity with mammalian Borna disease virus 1 (BoDV-1). The overall ... as the cause of proventricular dilatation disease (PDD), a disease of pet parrots. While a report of research using a 'positive ... Use of Avian Bornavirus Isolates to Induce Proventricular Dilatation Disease in Conures. Emerging Infectious Diseases, 16: 473- ... Ongoing studies suggest that the virus is spread by the fecal-oral route but it is also possible that respiratory and vertical ...
Laboratory rats infected with Borna disease virus show some symptoms similar to those of autism but blood studies of autistic ... Viruses have long been suspected as triggers for immune-mediated diseases such as multiple sclerosis but showing a direct role ... or whether they are secondary to the disease processes. As autoantibodies are found in diseases other than ASD, and are not ... Because diseases such as measles can cause severe disabilities and death, the risk of death or disability for an unvaccinated ...
Polio, measles, varicella-zoster, rubella, herpes simplex virus type 2, maternal genital infections, Borna disease virus, and ... a proximal cause of certain cases of schizophrenia is the interaction of the developing fetus with pathogens such as viruses, ... An updated meta-analysis on CNVs for schizophenia published in 2015 expanded the number of CNVs indicated in the disease, which ... In 2013 this dataset was expanded to identify in total 13 candidate loci for the disease, now also implicating calcium ...
... a family of viruses associated with Borna disease Borna disease virus Borna language (Democratic Republic of the Congo), a ... Borna may refer to: Borna, Leipzig, a town in Saxony, Germany Borna, a subdivision of Bahretal municipality, Saxony, German ... a Croatian masculine given name Bertin Borna (1930-2007), a Beninese politician Borna disease, an infectious neurological ... Borna Dam, an earthfill dam on Borna river near Ambejogai, Beed district, Maharashtra, India Borna (duke), the Duke of Dalmatia ...
Borna Disease Virus, das Virus der Bornaschen Krankheit, mit Species Mammalian 1 orthobornavirus (Typus) u. a. ... International Committee on Taxonomy of Viruses, Virus Taxonomy *↑ Insbesondere sind von Gattungen ohne jede Zuordnung nur ... Usutu-Virus - en. Usutu virus (USUV), Zika-Virus - en. Zika virus (ZIKV), sowie Gelbfieber-Virus - en. Yellow fever virus (YFV) ... Genus ‚Negevirus', mit Species ‚Blackford virus', ‚Bofa virus', ‚Buckhurst virus', ‚Marsac virus', sowie ‚Muthill virus'[53] ...
... possibly acting as a carrier of the virus. Borna diseases viruses 1 and 2 appear to have wide host ranges, having been detected ... Although Borna disease viruses 1 and 2 are mainly seen as the causative agent of Borna disease in horses and other animals, ... Borna disease is an infectious neurological syndrome of warm-blooded animals, caused by Borna disease viruses 1 and 2 (BoDV-1/2 ... Borna disease viruses 1 and 2 are neurotropic viruses and members of the Bornaviridae family within the Mononegavirales order. ...
Bode, L; Ludwig, H (2003). "Borna disease virus infection, a human mental-health risk". Clinical Microbiology Reviews. 16 (3): ... Atkinson, RL (2007). "Viruses as an etiology of obesity". Mayo Clinic Proceedings. 82 (10): 1192-8. doi:10.4065/82.10.1192. ... JC Virus and Simian Virus 40 Infection in Humans, and Association with Human Tumors". Polyomaviruses and Human Diseases. ... June 2010). "Virus-Plus-Susceptibility Gene Interaction Determines Crohn's Disease Gene Atg16L1 Phenotypes in Intestine". Cell ...
The Borna disease viruses (BoDV-1 and BoDV-2) are members of the species Mammalian 1 bornavirus, which cause Borna disease in ... The ancestral virus seems likely to have been a high AT content virus. Borna disease was first described in 1885 as "heated ... "N-terminal domain of Borna disease virus G (p56) protein is sufficient for virus receptor recognition and cell entry". Journal ... Wolff T, Pfleger R, Wehner T, Reinhardt J, Richt JA (April 2000). "A short leucine-rich sequence in the Borna disease virus p10 ...
Thogoto and Borna disease viruses". Virus Res. 95 (1-2): 3-12. doi:10.1016/S0168-1702(03)00159-X. PMID 12921991.. ... International Committee on Taxonomy of Viruses Index of Viruses - Orthomyxovirus (2006). In: ICTVdB-The Universal Virus ... Influenza virus A Influenza A virus* H1N1, H1N2, H2N2, H3N1, H3N2, H3N8, H5N1, H5N2, H5N3, H5N8, H5N9, H7N1, H7N2, H7N3, H7N4, ... "CIDRAP - Center for Infectious Disease Research and Policy. University of Minnesota.. *^ "Flu viruses 'can live for decades' on ...
Order Mononegavirales Family Bornaviridae - Borna disease virus Family Filoviridae - includes Ebola virus, Marburg virus Family ... parainfluenza viruses, influenza viruses, Ebola virus, Marburg virus are included within the NSV. The life cycle of NSV has a ... Viruses of the family Tenuivirus only infect plants. A few viruses known to infect humans include Marburg virus, Ebola, measles ... A negative-sense single-stranded RNA virus (or (-)ssRNA virus) is a virus that uses negative sense, single-stranded RNA as its ...
Diseases associated with bornaviruses include Borna disease, a fatal neurologic disease of mammals restricted to central Europe ... "Is There a Killer Squirrel Virus?". 9 July 2015. Viralzone: Bornaviridae Bornavirus/host Interactome ICTV Borna: Bornaviridae. ... Currently, 16 viruses are assigned to eight species included in one genus in this family. ... and proventricular dilatation disease in birds. Borna disease was first identified in 1926 and its genome was isolated in 1990 ...
... includes Borna disease virus Family Filoviridae - includes Ebola virus, Marburg virus Family Mymonaviridae Family Nyamiviridae ... Viruses portal Virus classification List of viruses Viral replication Positive/negative-sense Animal viruses Double-stranded ... virus Extra small virus Jingmen tick virus Le Blanc virus Nesidiocoris tenuis virus 1 Nylanderia fulva virus 1 Orsay virus ... Family Paramyxoviridae - includes Measles virus, Mumps virus, Nipah virus, Hendra virus, and Newcastle disease virus Family ...
Thogoto and Borna disease viruses". Virus Res. 95 (1-2): 3-12. doi:10.1016/S0168-1702(03)00159-X. PMID 12921991. Kash, J; ... In virus classification influenza viruses are RNA viruses that make up three of the five genera of the family Orthomyxoviridae ... The type A viruses are the most virulent human pathogens among the three influenza types and cause the severest disease. The ... Viruses can replicate only in living cells. Influenza infection and replication is a multi-step process: First, the virus has ...
Thogoto and Borna disease viruses". Virus Res. 95 (1-2): 3-12. doi:10.1016/S0168-1702(03)00159-X. PMID 12921991.. Parameter , ... Virus influenza C. Virus-virus tersebut memiliki kekerabatan yang jauh dengan virus parainfluenza manusia, yang merupakan virus ... Jenis-jenis virusSunting. Dalam klasifikasi virus, virus influenza termasuk virus RNA yang merupakan tiga dari lima genera ... Virus influenza A subtipe H10N7. Virus influenza BSunting. Genus ini memiliki satu spesies, yaitu virus influenza B. influenza ...
... borna disease virus MeSH B04.820.455.300 --- filoviridae MeSH B04.820.455.300.200 --- ebola-like viruses MeSH B04.820.455.300. ... borna disease virus MeSH B04.909.777.455.300 --- filoviridae MeSH B04.909.777.455.300.200 --- ebola-like viruses MeSH B04.909. ... bluetongue virus MeSH B04.820.630.550.400 --- hemorrhagic disease virus, epizootic MeSH B04.820.630.550.750 --- palyam virus ... yellow fever virus MeSH B04.820.250.400 --- gb virus a MeSH B04.820.250.405 --- gb virus b MeSH B04.820.250.410 --- GB virus C ...
Thogoto and Borna disease viruses". Virus Research. 95 (1-2): 3-12. doi:10.1016/S0168-1702(03)00159-X. PMID 12921991.. ... In virus classification, influenza viruses are RNA viruses that make up four of the seven genera of the family Orthomyxoviridae ... These viruses are only distantly related to the human parainfluenza viruses, which are RNA viruses belonging to the ... how the virus produces disease (pathogenesis), host immune responses, viral genomics, and how the virus spreads (epidemiology ...
Many serious diseases such as Ebola virus disease, AIDS, avian influenza, and SARS are caused by viruses. The relative ability ... Chen C, Chiu Y, Wei F, Koong F, Liu H, Shaw C, Hwu H, Hsiao K. High seroprevalence of Borna virus infection in schizophrenic ... I: dsDNA viruses. II: ssDNA viruses. III: dsRNA viruses. IV: (+)ssRNA viruses. V: (−)ssRNA viruses. VI: ssRNA-RT viruses. VII: ... A virus has either a DNA or an RNA genome and is called a DNA virus or an RNA virus, respectively. The vast majority of viruses ...
Many serious diseases such as Ebola virus disease, AIDS, avian influenza, and SARS are caused by viruses. The relative ability ... Chen C, Chiu Y, Wei F, Koong F, Liu H, Shaw C, Hwu H, Hsiao K. High seroprevalence of Borna virus infection in schizophrenic ... A virus has either a DNA or an RNA genome and is called a DNA virus or an RNA virus, respectively. The vast majority of viruses ... Viruses are important pathogens of livestock. Diseases such as foot-and-mouth disease and bluetongue are caused by viruses. ...
科薩努爾森林病(英語:Kyasanur forest disease) *KFDV(英語:Kyasanur forest disease virus) ... Field, H., Young, P., Yob, J. M., Mills, J., Hall, L., Mackenzie, J. The natural history of Hendra and Nipah viruses. Microbes ... 玻那病毒Borna virusinfection. *馬爾堡病毒. *裂谷熱Rift Valley fever ... N, 580-629(英語:List of ICD-9 codes 580-629: diseases of the genitourinary system)). *Urologic disease(英
Many serious diseases such as Ebola virus disease, AIDS, avian influenza, and SARS are caused by viruses. The relative ability ... Chen C, Chiu Y, Wei F, Koong F, Liu H, Shaw C, Hwu H, Hsiao K. High seroprevalence of Borna virus infection in schizophrenic ... A virus has either a DNA or an RNA genome and is called a DNA virus or an RNA virus, respectively. The vast majority of viruses ... Animal viruses. Main articles: Animal virus and Veterinary virology. Viruses are important pathogens of livestock. Diseases ...
The Borna disease viruses (BoDV-1 and BoDV-2) are members of the species Mammalian 1 bornavirus, which cause Borna disease in ... The ancestral virus seems likely to have been a high AT content virus. Borna disease was first described in 1885 as "heated ... "N-terminal domain of Borna disease virus G (p56) protein is sufficient for virus receptor recognition and cell entry". Journal ... Wolff T, Pfleger R, Wehner T, Reinhardt J, Richt JA (April 2000). "A short leucine-rich sequence in the Borna disease virus p10 ...
... with specific interests in virus infection and human neuropsychiatric diseases. The establishment of sensitive immunoassays ... notably on molecular genetics of RNA virus, neurobiology, biological psychiatry, and public health. In this chapter, author ... The study of Borna disease virus (BDV) and BD has broad impact on diverse areas of biology and medicine, ... using infected culture cells also contributed to the characterization of virus specific antibodies. These assays were relevant ...
To favor their replication, viruses express proteins that target diverse mammalian cellular pathways. Due to the limited size ... One salient example is the X protein of Borna disease virus, which is expressed both at the mitochondria and in the nucleus. ... Manipulation of the N-terminal sequence of the Borna disease virus X protein improves its mitochondrial targeting and ... Manipulation of the N-terminal sequence of the Borna disease virus X protein improves its mitochondrial targeting and ...
... virus in cell cultures was investigated. Acutely BD virus-infected primary rabbit brain and rat lung cells produced significant ... Rat brain and rat lung cells persistently infected with BD virus produced only moderate levels of IFN over a long period. In ... Thus, MDCK cells, which could not be induced to produce IFN, can be readily persistently infected with BD virus in vitro, and ... However, IFN added to persistently infected rat lung cells did not appear to influence the degree or quality of BD virus ...
Antibodies to both the virus G and M (gp18) proteins have neutralizing activity, suggesting that both are implicated in BDV ... However, recent findings have indicated that rabies virus (RV) G is absolutely required for the propagation of RV in neuronal ... BDV infection produces a range of phenotypic disease expression. BDV has a non-segmented, negative-stranded (NNS) RNA genome. ... but full virus particles have never been observed at the site of synaptic junctions. These observations led to the attractive ...
Borna Disease Borna Disease Virus Crocidura Leucodon Germany Immunohistochemical Analysis Indirect Immunofluorescence Assay ... Borna disease virus, a newly classified nonsegmented negative-strand RNA virus with international distribution, infects a broad ... Borna disease virus (BDV) is the causative agent of severe T-cell-mediated meningoencephalitis in horses, sheep, and other ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ...
Bornaviridae, a family of viruses associated with Borna disease. *Borna disease virus ... Bertin Borna (1930-2007), a Beninese politician. Other uses[edit]. *Borna disease, an infectious neurological syndrome * ... Borna, a subdivision of Bahretal municipality, Saxony, German. *Borna Dam, an earthfill dam on Borna river near Ambejogai, Beed ... Borna language (Ethiopia), a North Omotic language spoken in western Ethiopia. *Borna snakehead, Channa amphibeus, an extremely ...
Borna disease virus infection of the neonatal rat: developmental brain injury model of autism spectrum disorders. Frontiers in ... Borna disease virus infection of the neonatal rat : developmental brain injury model of autism spectrum disorders. / Pletnikov ... Pletnikov, M., Moran, T. H., & Carbone, K. M. (2002). Borna disease virus infection of the neonatal rat: developmental brain ... title = "Borna disease virus infection of the neonatal rat: developmental brain injury model of autism spectrum disorders.", ...
You are here LABOKLIN / Products / Infectious Diseases: Pathogenic Agents and Antibody Detection / Viruses / Borna Disease ... This virus triggers the co-called Borna disease in mammals and the proventricular dilatation disease in birds. ... Avian Borna viruses are RNA viruses which show high genetic divergence. A negative result does therefore not entirely rule out ... The Borna virus is a non-segmented, enveloped RNA virus which constitutes the only member of the family Bornaviridae. ...
Borna disease virus (BDV) replicates and transcribes its negative-sense RNA genome in the nucleus. The BDV phosphoprotein (P) ... Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures Richard E. ... Characterization of the major nuclear localization signal of the Borna disease virus phosphoprotein. * M Schwemmle, C Jehle, T ... Borna disease virus (BDV) replicates and transcribes its negative-sense RNA genome in the nucleus. The BDV phosphoprotein (P) ...
N2 - Borna disease virus (BDV) is a noncytolytic, neurotropic RNA virus that has a broad host range in warm-blooded animals, ... AB - Borna disease virus (BDV) is a noncytolytic, neurotropic RNA virus that has a broad host range in warm-blooded animals, ... Borna disease virus (BDV) is a noncytolytic, neurotropic RNA virus that has a broad host range in warm-blooded animals, ... abstract = "Borna disease virus (BDV) is a noncytolytic, neurotropic RNA virus that has a broad host range in warm-blooded ...
The hypothesis that microbial infections may be linked to mental disorders has long been addressed for Borna disease virus (BDV ... herpes viruses and schizophrenia [2]. However, a link, whatsoever, to Borna disease virus (BDV) appeared as a particularly ... de la Torre JC, Bode L, Dürrwald R, Cubitt B, Ludwig H. Sequence characterization of human Borna disease virus. Virus Res. 1996 ... Ludwig H, Bode L. Borna disease virus: new aspects on infection, disease, diagnosis and epidemiology. Rev Sci Tech. 2000;19:259 ...
... is an evolutionary old RNA virus, which infects brain and blood cells of humans, their primate ancestors, and other mammals. ... Virus taxonomy 283, classification and nomenclature of viruses. 284 Seventh report of the International Committee on Taxonomy ... Borna disease virus (BDV) is an evolutionary old RNA virus, which infects brain and blood cells of humans, their primate ... de la Torre JC, Bode L, Duerrwald R, Cubitt B, Ludwig H: Sequence characterization of human Borna disease virus. Virus Res. ...
The etiologic agent, Borna disease virus (BDV), has been identified as an enveloped nonsegmented negative-strand RNA virus with ... the disease is caused by a virus-induced T-cell--mediated immune reaction. Because antibodies reactive with BDV have been found ... a fatal neurologic disease of horses and sheep, are larger than previously thought. ... The geographic distribution and host range of Borna disease (BD), ...
Whether Borna disease virus (BDV-1) is a human pathogen remained controversial until recent encephalitis cases showed BDV-1 ... Biology and neurobiology of Borna disease viruses (BDV), defined by antibodies, neutralizability and their pathogenic potential ... de la Torre JC, Bode L, Dürrwald R, Cubitt B, Ludwig H. Sequence characterization of human Borna disease virus. Virus Res. 1996 ... Human infections with Borna disease virus: seroprevalence in patients with chronic diseases and healthy individuals. J Med ...
The novel VSBV-1 was found to be a phylogenetically unique lineage from previously described Borna disease viruses (1). Never ... Only further research will reveal the who/what/where are most at risk of the newly described Borna disease virus, VSBV-1. ... or for Borna disease viruses in humans. Researchers cannot say for certain that VSBV-1 was the etiologic source of the three ... Lyme Disease Cases Triple in the US. Lyme disease has been strongly concentrated in the North American Midwest and Northeastern ...
Experiences of Borna Disease Virus infection in Sweden pp. 46-49(4) Authors: BERG, MIKAEL; BERG, ANNA-LENA; WENSMAN, JONAS J. ... Evolution of viruses and their impact on human life: HIV-1 subgroup M pp. 7-13(7) Author: BECKER, YECHIEL ... Human Borna disease virus-infection and its therapy in affective disorders pp. 61-65(5) Authors: BODE, LIV; DIETRICH, DETLEF E. ... Borna disease virus infection in Italian children. A potential risk for the developing brain? pp. 70-73(4) Authors: VULCANO, ...
... neonatal Borna disease [NBD]) results in cerebellar damage without the cellular inflammation associated with infections in ... Infection of newborn Lewis rats with Borna disease virus ( ... Borna Disease / metabolism*, pathology. Borna disease virus*. ... Previous Document: NS1 proteins of avian influenza A viruses can act as antagonists of the human alpha/beta interferon .... ... Infection of newborn Lewis rats with Borna disease virus (neonatal Borna disease [NBD]) results in cerebellar damage without ...
Selected viruses. Genome. Adenoviridae. Adenovirus. dsDNA. Arenaviridae. Lassa virus. ssRNA. Bornaviridae. Borna disease virus ... Coxsackie virus, foot-and-mouth disease virus, hepatitis A virus, poliovirus, rhinovirus. ssRNA. ... RNA viruses. Some viruses have a single- or double-stranded RNA genome (see table Selected RNA viruses). Viral RNA is typically ... Human foamy virus, human immunodeficiency virus, human T-cell leukemia virus. ssRNA. ...
Epidemiology of Borna disease virus. P Staeheli, C Sauder, J Hausmann, F Ehrensperger, M Schwemmle ... Pandemic influenza A viruses escape from restriction by human MxA through adaptive mutations in the nucleoprotein. B M nz, D ... Binding of Epstein-Barr virus small RNA EBER-1 to the double-stranded RNA-activated protein kinase DAI. PA Clarke, M Schwemmle ... Adaptation of avian influenza A virus polymerase in mammals to overcome the host species barrier. B M nz, M Schwemmle, L ...
Bicolored white-toothed shrews as reservoir for Borna disease virus, Bavaria, Germany ... Several viruses associated with the old-world subfamily Murinae cause hemorrhagic fever with renal syndrome (HFRS) in Asia and ... Asian musk shrew as a reservoir of rat hepatitis E virus, China ...
... a multifunctional protein involved in all stages of viral mRNA processing and that is essential for virus replication. Using ... Many viruses replicate in the nucleus of the host cell and require cellular mRNA export factors to efficiently export viral ... However, some viral mRNAs undergo aberrant mRNA processing, thus prompting the viruses to express their own specific mRNA ... before exploring how the virus has evolved to exploit these mechanisms. ...
borna disease synonyms, borna disease pronunciation, borna disease translation, English dictionary definition of borna disease ... n vet science a viral disease of mammals, esp horses, caused by a member of the Flaviviridae and characterized by the ... Supply and Delivery of Borna Disease Virus Proteins. Asc - Supply And Delivery Of Borna Disease Virus Proteins ... in animals help to bring the infection-based model of schizophrenia to the realm of scientific imagination Viruses can ...
... termed proventricular dilatation disease (PDD). We successfully isolated and characterized ABV from the brains of 8 birds with ... Borna disease virus (BDV). BDV causes a neurologic syndrome, Borna disease, which is restricted to central Europe, where it is ... Borna disease virus, a negative-strand RNA virus, transcribes in the nucleus of infected cells. Proc Natl Acad Sci U S A. 1992; ... Interactions of the borna disease virus P, N, and X proteins and their functional implications. J Biol Chem. 1998;273:9007-12. ...
Borna Disease Virus. *Botulism. *Bovine Spongiform Encephalopathy (BSE). *Brachial Plexopathies. *Brain Anatomy ... Human T-Cell Lymphotropic Viruses (HTLVs). *Hun, Henry. *Huntington, George. *Huntingtons Disease ...
  • In 2015, German officials reported a cluster of three acute fatal encephalitis cases in the Saxony-Anhalt region to the Early Warning and Response System of the European Center for Disease Control (ECDC) (4). (healthmap.org)
  • Dr. Sunit Kumar Singh is a Scientist & Project Leader in the Section of Infectious Diseases and Immunobiology, Centre for Cellular and Molecular Biology (CCMB), Hyderabad, India, Dr. Singh leads a research group in neurovirology, and his broad?areas of expertise?are in?neurovirology and neuroinflammation. (wiley.com)
  • A similar dependence on noncytolytic immune clearance has also been shown for Sindbis virus ( 2 ), mouse hepatitis virus ( 26 , 34 , 48 ), and vesicular stomatitis virus ( 22 - 24 ). (asm.org)
  • The etiologic agent, Borna disease virus (BDV), has been identified as an enveloped nonsegmented negative-strand RNA virus with unique properties of replication. (cdc.gov)
  • The etiologic agent of BD, BDV, has been recently characterized as an enveloped, nonsegmented, negative-stranded RNA virus with a genomic size of approximately 9 kb and a nuclear site for replication and transcription ( 14 - 17 ). (cdc.gov)
  • Replication of primate foamy viruses in natural and experimental hosts. (uniklinik-freiburg.de)
  • Virus classification is based mainly on phenotypic characteristics, including morphology , nucleic acid type, mode of replication, host organisms , and the type of disease they cause. (wikidoc.org)
  • Baltimore classification (first defined in 1971) is a classification system which places viruses into one of seven groups depending on a combination of their nucleic acid ( DNA or RNA ), strandedness (single-stranded or double-stranded), and method of replication . (wikidoc.org)
  • In situ hybridization indicates TiLV replication and transcription at sites of pathology in the liver and central nervous system of tilapia with disease. (asm.org)
  • Representing a major addition to the world literature on the subject, Viral Infections and Global Change explores trends of paramount concern globally, regarding the emergence and reemergence of vector-borne and zoonotic viruses. (wiley.com)
  • Viral Infections and Global Change is an indispensable resource for research scientists, epidemiologists, and medical and veterinary students working in ecology, environmental management, climatology, neurovirology, virology, and infectious disease. (wiley.com)
  • Thus, virus infections that result in neuronal depletion, either by virus-mediated cell death or by induction of the cytolytic immune response, could cause permanent neurological impairment of the host. (asm.org)
  • However, immune-mediated lysis of infected cells may not be an optimal strategy for clearance of all virus infections, especially those that involve tissues with little capacity for renewal, such as the central nervous system (CNS) ( 38 , 42 ). (asm.org)
  • PC inhibitors are suggested as promising antiviral drugs for quite a number of viruses causing severe infections. (springer.com)
  • Researchers are finding evidence that some diseases with only psychological symptoms could be triggered by infections or abnormalities of the immune system. (chicagotribune.com)
  • In 1985, Amsterdam and a group of colleagues at Penn and the neighboring Wistar Institute tested 265 patients at Penn's depression clinic for the presence of the Borna virus, and compared them with a group of 105 healthy control subjects. (chicagotribune.com)
  • It has since been recognized as an often-fatal disease affecting a range of livestock and domestic animals (5). (healthmap.org)
  • The most recent experiments demonstrate the utility of the BDV model for studying the pathophysiological mechanisms of the gene-environment interaction that determines differential disease outcomes and variability in responses to treatments. (elsevier.com)
  • Since gene products as well as RNA genomes of these non-segmented negative strand (NNS) RNA viruses share structural and functional similarities, they are believed to have evolved from a common ancestor. (frontiersin.org)
  • Novel gene product of Thogoto Virus segment 6 codes for an interferon antagonist. (uniklinik-freiburg.de)
  • Analysis of the glycoprotein gene of Tacaribe virus and neutralization-resistant variants. (springer.com)
  • viruses possess double-stranded DNA and include such virus families as Herpesviridae (examples like HSV1 ( oral herpes ), HSV2 ( genital herpes ), VZV ( chickenpox ), EBV ( Epstein-Barr virus ), CMV ( Cytomegalovirus )), Poxviridae (smallpox) and many tailed bacteriophages . (wikidoc.org)
  • In some circumstances, including herpes simplex virus encephalitis, such inflammatory responses are associated with marked CNS damage ( 19 ). (asm.org)
  • Many well known viruses are found in this group, including the picornaviruses (which is a family of viruses that includes well-known viruses like Hepatitis A virus, enteroviruses, rhinoviruses, poliovirus, and foot-and-mouth virus), SARS virus, hepatitis C virus, yellow fever virus, and rubella virus. (wikidoc.org)
  • A few people have tested positive for this virus, and a disproportionate number of those are also clinically depressed, leading researchers to suspect a connection. (chicagotribune.com)
  • Virus expert Hillary Koprowski of Thomas Jefferson University, who has collaborated with the Penn researchers, is skeptical that the depressed people really have the virus. (chicagotribune.com)
  • The virus etiology of BD was proven in the early 1900s when Zwick and coworkers (1) in Giessen, Germany, successfully transmitted brain homogenates from infected horses to experimental animals. (cdc.gov)
  • Accompanying this broad method of classification are specific naming conventions and further classification guidelines set out by the International Committee on Taxonomy of Viruses . (wikidoc.org)
  • Die Entscheidung über verschiedene Taxa wird von einem internationalen Gremium, dem International Committee on Taxonomy of Viruses (ICTV), beraten und getroffen. (wikipedia.org)