The study of the structure, growth, function, genetics, and reproduction of viruses, and VIRUS DISEASES.
Minute infectious agents whose genomes are composed of DNA or RNA, but not both. They are characterized by a lack of independent metabolism and the inability to replicate outside living host cells.
A general term for diseases produced by viruses.
Biological properties, processes, and activities of VIRUSES.
Proteins found in any species of virus.
Ribonucleic acid that makes up the genetic material of viruses.
The process of intracellular viral multiplication, consisting of the synthesis of PROTEINS; NUCLEIC ACIDS; and sometimes LIPIDS, and their assembly into a new infectious particle.
The functional hereditary units of VIRUSES.
The study of infectious diseases associated with plants.
Deoxyribonucleic acid that makes up the genetic material of viruses.
Time period from 1901 through 2000 of the common era.
Time period from 2001 through 2100 of the common era.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The complete genetic complement contained in a DNA or RNA molecule in a virus.
Facilities equipped to carry out investigative procedures.
Process of growing viruses in live animals, plants, or cultured cells.
Established cell cultures that have the potential to propagate indefinitely.
The type species of ALPHAVIRUS normally transmitted to birds by CULEX mosquitoes in Egypt, South Africa, India, Malaya, the Philippines, and Australia. It may be associated with fever in humans. Serotypes (differing by less than 17% in nucleotide sequence) include Babanki, Kyzylagach, and Ockelbo viruses.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
The infective system of a virus, composed of the viral genome, a protein core, and a protein coat called a capsid, which may be naked or enclosed in a lipoprotein envelope called the peplos.
Any of the processes by which cytoplasmic factors influence the differential control of gene action in viruses.
The outer protein protective shell of a virus, which protects the viral nucleic acid.
A strain of PRIMATE T-LYMPHOTROPIC VIRUS 3 that is genetically similar to STLV-3.
A CELL LINE derived from the kidney of the African green (vervet) monkey, (CERCOPITHECUS AETHIOPS) used primarily in virus replication studies and plaque assays.
The type species of ORTHOPOXVIRUS, related to COWPOX VIRUS, but whose true origin is unknown. It has been used as a live vaccine against SMALLPOX. It is also used as a vector for inserting foreign DNA into animals. Rabbitpox virus is a subspecies of VACCINIA VIRUS.
A species of CERCOPITHECUS containing three subspecies: C. tantalus, C. pygerythrus, and C. sabeus. They are found in the forests and savannah of Africa. The African green monkey (C. pygerythrus) is the natural host of SIMIAN IMMUNODEFICIENCY VIRUS and is used in AIDS research.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
The assembly of VIRAL STRUCTURAL PROTEINS and nucleic acid (VIRAL DNA or VIRAL RNA) to form a VIRUS PARTICLE.
Layers of protein which surround the capsid in animal viruses with tubular nucleocapsids. The envelope consists of an inner layer of lipids and virus specified proteins also called membrane or matrix proteins. The outer layer consists of one or more types of morphological subunits called peplomers which project from the viral envelope; this layer always consists of glycoproteins.
Viruses which lack a complete genome so that they cannot completely replicate or cannot form a protein coat. Some are host-dependent defectives, meaning they can replicate only in cell systems which provide the particular genetic function which they lack. Others, called SATELLITE VIRUSES, are able to replicate only when their genetic defect is complemented by a helper virus.
Proteins that form the CAPSID of VIRUSES.
A family of enveloped, linear, double-stranded DNA viruses infecting a wide variety of animals. Subfamilies, based on biological characteristics, include: ALPHAHERPESVIRINAE; BETAHERPESVIRINAE; and GAMMAHERPESVIRINAE.
Substances elaborated by viruses that have antigenic activity.
Species of the genus MASTADENOVIRUS, causing a wide range of diseases in humans. Infections are mostly asymptomatic, but can be associated with diseases of the respiratory, ocular, and gastrointestinal systems. Serotypes (named with Arabic numbers) have been grouped into species designated Human adenovirus A-F.
A species of VARICELLOVIRUS causing abortion and respiratory disease in horses.
Immunoglobulins produced in response to VIRAL ANTIGENS.
An enzyme that catalyses RNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time, and can initiate a chain de novo. (Enzyme Nomenclature, 1992, p293)
Viruses whose genetic material is RNA.
Visible morphologic changes in cells infected with viruses. It includes shutdown of cellular RNA and protein synthesis, cell fusion, release of lysosomal enzymes, changes in cell membrane permeability, diffuse changes in intracellular structures, presence of viral inclusion bodies, and chromosomal aberrations. It excludes malignant transformation, which is CELL TRANSFORMATION, VIRAL. Viral cytopathogenic effects provide a valuable method for identifying and classifying the infecting viruses.
A genus of the family PICORNAVIRIDAE whose members preferentially inhabit the intestinal tract of a variety of hosts. The genus contains many species. Newly described members of human enteroviruses are assigned continuous numbers with the species designated "human enterovirus".
The type species of the genus INFLUENZAVIRUS A that causes influenza and other diseases in humans and animals. Antigenic variation occurs frequently between strains, allowing classification into subtypes and variants. Transmission is usually by aerosol (human and most non-aquatic hosts) or waterborne (ducks). Infected birds shed the virus in their saliva, nasal secretions, and feces.
Viral proteins that are components of the mature assembled VIRUS PARTICLES. They may include nucleocapsid core proteins (gag proteins), enzymes packaged within the virus particle (pol proteins), and membrane components (env proteins). These do not include the proteins encoded in the VIRAL GENOME that are produced in infected cells but which are not packaged in the mature virus particle,i.e. the so called non-structural proteins (VIRAL NONSTRUCTURAL PROTEINS).
A system for verifying and maintaining a desired level of quality in a product or process by careful planning, use of proper equipment, continued inspection, and corrective action as required. (Random House Unabridged Dictionary, 2d ed)
Viruses whose nucleic acid is DNA.
Proteins encoded by a VIRAL GENOME that are produced in the organisms they infect, but not packaged into the VIRUS PARTICLES. Some of these proteins may play roles within the infected cell during VIRUS REPLICATION or act in regulation of virus replication or VIRUS ASSEMBLY.
The type species of TOBAMOVIRUS which causes mosaic disease of tobacco. Transmission occurs by mechanical inoculation.
The type species of LENTIVIRUS and the etiologic agent of AIDS. It is characterized by its cytopathic effect and affinity for the T4-lymphocyte.
Method for measuring viral infectivity and multiplication in CULTURED CELLS. Clear lysed areas or plaques develop as the VIRAL PARTICLES are released from the infected cells during incubation. With some VIRUSES, the cells are killed by a cytopathic effect; with others, the infected cells are not killed but can be detected by their hemadsorptive ability. Sometimes the plaque cells contain VIRAL ANTIGENS which can be measured by IMMUNOFLUORESCENCE.
Specific molecular components of the cell capable of recognizing and interacting with a virus, and which, after binding it, are capable of generating some signal that initiates the chain of events leading to the biological response.
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
A sequence of successive nucleotide triplets that are read as CODONS specifying AMINO ACIDS and begin with an INITIATOR CODON and end with a stop codon (CODON, TERMINATOR).
A genus of the family HERPESVIRIDAE, subfamily ALPHAHERPESVIRINAE, consisting of herpes simplex-like viruses. The type species is HERPESVIRUS 1, HUMAN.
A genus of owlet moths of the family Noctuidae. These insects are used in molecular biology studies during all stages of their life cycle.
Viruses parasitic on plants higher than bacteria.
A species of the CORONAVIRUS genus causing hepatitis in mice. Four strains have been identified as MHV 1, MHV 2, MHV 3, and MHV 4 (also known as MHV-JHM, which is neurotropic and causes disseminated encephalomyelitis with demyelination as well as focal liver necrosis).
A subfamily in the family MURIDAE, comprising the hamsters. Four of the more common genera are Cricetus, CRICETULUS; MESOCRICETUS; and PHODOPUS.
Suspensions of attenuated or killed viruses administered for the prevention or treatment of infectious viral disease.
A species of ENTEROVIRUS which is the causal agent of POLIOMYELITIS in humans. Three serotypes (strains) exist. Transmission is by the fecal-oral route, pharyngeal secretions, or mechanical vector (flies). Vaccines with both inactivated and live attenuated virus have proven effective in immunizing against the infection.
The type species of SIMPLEXVIRUS causing most forms of non-genital herpes simplex in humans. Primary infection occurs mainly in infants and young children and then the virus becomes latent in the dorsal root ganglion. It then is periodically reactivated throughout life causing mostly benign conditions.
A genus of the family HERPESVIRIDAE, subfamily BETAHERPESVIRINAE, infecting the salivary glands, liver, spleen, lungs, eyes, and other organs, in which they produce characteristically enlarged cells with intranuclear inclusions. Infection with Cytomegalovirus is also seen as an opportunistic infection in AIDS.
Production of new arrangements of DNA by various mechanisms such as assortment and segregation, CROSSING OVER; GENE CONVERSION; GENETIC TRANSFORMATION; GENETIC CONJUGATION; GENETIC TRANSDUCTION; or mixed infection of viruses.
The process by which a DNA molecule is duplicated.
Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2.
Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases.
The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION.
The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.
A plant genus of the family SOLANACEAE. Members contain NICOTINE and other biologically active chemicals; its dried leaves are used for SMOKING.
Proteins, usually glycoproteins, found in the viral envelopes of a variety of viruses. They promote cell membrane fusion and thereby may function in the uptake of the virus by cells.
The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.
A genus of FLAVIVIRIDAE causing parenterally-transmitted HEPATITIS C which is associated with transfusions and drug abuse. Hepatitis C virus is the type species.
The relationships of groups of organisms as reflected by their genetic makeup.
An acute viral infection in humans involving the respiratory tract. It is marked by inflammation of the NASAL MUCOSA; the PHARYNX; and conjunctiva, and by headache and severe, often generalized, myalgia.
The biosynthesis of PEPTIDES and PROTEINS on RIBOSOMES, directed by MESSENGER RNA, via TRANSFER RNA that is charged with standard proteinogenic AMINO ACIDS.
An inheritable change in cells manifested by changes in cell division and growth and alterations in cell surface properties. It is induced by infection with a transforming virus.
Duplex DNA sequences in eukaryotic chromosomes, corresponding to the genome of a virus, that are transmitted from one cell generation to the next without causing lysis of the host. Proviruses are often associated with neoplastic cell transformation and are key features of retrovirus biology.
Sudden increase in the incidence of a disease. The concept includes EPIDEMICS and PANDEMICS.
DNA molecules capable of autonomous replication within a host cell and into which other DNA sequences can be inserted and thus amplified. Many are derived from PLASMIDS; BACTERIOPHAGES; or VIRUSES. They are used for transporting foreign genes into recipient cells. Genetic vectors possess a functional replicator site and contain GENETIC MARKERS to facilitate their selective recognition.
Procedures for collecting, preserving, and transporting of specimens sufficiently stable to provide accurate and precise results suitable for clinical interpretation.
Virus diseases caused by the HERPESVIRIDAE.
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
The interactions between a host and a pathogen, usually resulting in disease.
The first continuously cultured human malignant CELL LINE, derived from the cervical carcinoma of Henrietta Lacks. These cells are used for VIRUS CULTIVATION and antitumor drug screening assays.
A genus of the family BACULOVIRIDAE, subfamily Eubaculovirinae, characterized by the formation of crystalline, polyhedral occlusion bodies in the host cell nucleus. The type species is Autographa californica nucleopolyhedrovirus.
The type species of VESICULOVIRUS causing a disease symptomatically similar to FOOT-AND-MOUTH DISEASE in cattle, horses, and pigs. It may be transmitted to other species including humans, where it causes influenza-like symptoms.
The measurement of infection-blocking titer of ANTISERA by testing a series of dilutions for a given virus-antiserum interaction end-point, which is generally the dilution at which tissue cultures inoculated with the serum-virus mixtures demonstrate cytopathology (CPE) or the dilution at which 50% of test animals injected with serum-virus mixtures show infectivity (ID50) or die (LD50).
Family of INSECT VIRUSES containing two subfamilies: Eubaculovirinae (occluded baculoviruses) and Nudibaculovirinae (nonoccluded baculoviruses). The Eubaculovirinae, which contain polyhedron-shaped inclusion bodies, have two genera: NUCLEOPOLYHEDROVIRUS and GRANULOVIRUS. Baculovirus vectors are used for expression of foreign genes in insects.
The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.
The type species of the genus ORTHOHEPADNAVIRUS which causes human HEPATITIS B and is also apparently a causal agent in human HEPATOCELLULAR CARCINOMA. The Dane particle is an intact hepatitis virion, named after its discoverer. Non-infectious spherical and tubular particles are also seen in the serum.
Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
Proteins found mainly in icosahedral DNA and RNA viruses. They consist of proteins directly associated with the nucleic acid inside the NUCLEOCAPSID.
INFLAMMATION of the LIVER in humans caused by HEPATITIS C VIRUS, a single-stranded RNA virus. Its incubation period is 30-90 days. Hepatitis C is transmitted primarily by contaminated blood parenterally, and is often associated with transfusion and intravenous drug abuse. However, in a significant number of cases, the source of hepatitis C infection is unknown.
A family of small, non-enveloped DNA viruses infecting birds and most mammals, especially humans. They are grouped into multiple genera, but the viruses are highly host-species specific and tissue-restricted. They are commonly divided into hundreds of papillomavirus "types", each with specific gene function and gene control regions, despite sequence homology. Human papillomaviruses are found in the genera ALPHAPAPILLOMAVIRUS; BETAPAPILLOMAVIRUS; GAMMAPAPILLOMAVIRUS; and MUPAPILLOMAVIRUS.
Enzymes that catalyze DNA template-directed extension of the 3'-end of an RNA strand one nucleotide at a time. They can initiate a chain de novo. In eukaryotes, three forms of the enzyme have been distinguished on the basis of sensitivity to alpha-amanitin, and the type of RNA synthesized. (From Enzyme Nomenclature, 1992).
Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS).
Recombinant proteins produced by the GENETIC TRANSLATION of fused genes formed by the combination of NUCLEIC ACID REGULATORY SEQUENCES of one or more genes with the protein coding sequences of one or more genes.
The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.
The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.
The spatial arrangement of the atoms of a nucleic acid or polynucleotide that results in its characteristic 3-dimensional shape.
Family of RNA viruses that infects birds and mammals and encodes the enzyme reverse transcriptase. The family contains seven genera: DELTARETROVIRUS; LENTIVIRUS; RETROVIRUSES TYPE B, MAMMALIAN; ALPHARETROVIRUS; GAMMARETROVIRUS; RETROVIRUSES TYPE D; and SPUMAVIRUS. A key feature of retrovirus biology is the synthesis of a DNA copy of the genome which is integrated into cellular DNA. After integration it is sometimes not expressed but maintained in a latent state (PROVIRUSES).
A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.
Proteins coded by the retroviral gag gene. The products are usually synthesized as protein precursors or POLYPROTEINS, which are then cleaved by viral proteases to yield the final products. Many of the final products are associated with the nucleoprotein core of the virion. gag is short for group-specific antigen.
Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.
Deletion of sequences of nucleic acids from the genetic material of an individual.
Use of restriction endonucleases to analyze and generate a physical map of genomes, genes, or other segments of DNA.
A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.
The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.
Genetically engineered MUTAGENESIS at a specific site in the DNA molecule that introduces a base substitution, or an insertion or deletion.
Process of generating a genetic MUTATION. It may occur spontaneously or be induced by MUTAGENS.
The type species of LYMPHOCRYPTOVIRUS, subfamily GAMMAHERPESVIRINAE, infecting B-cells in humans. It is thought to be the causative agent of INFECTIOUS MONONUCLEOSIS and is strongly associated with oral hairy leukoplakia (LEUKOPLAKIA, HAIRY;), BURKITT LYMPHOMA; and other malignancies.
Genotypic differences observed among individuals in a population.
Conjugated protein-carbohydrate compounds including mucins, mucoid, and amyloid glycoproteins.
Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS.
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
Proteins prepared by recombinant DNA technology.
INFLAMMATION of the LIVER in humans caused by a member of the ORTHOHEPADNAVIRUS genus, HEPATITIS B VIRUS. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact.
Sites on an antigen that interact with specific antibodies.
The part of a cell that contains the CYTOSOL and small structures excluding the CELL NUCLEUS; MITOCHONDRIA; and large VACUOLES. (Glick, Glossary of Biochemistry and Molecular Biology, 1990)
An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.
Elements of limited time intervals, contributing to particular results or situations.
The developmental entity of a fertilized chicken egg (ZYGOTE). The developmental process begins about 24 h before the egg is laid at the BLASTODISC, a small whitish spot on the surface of the EGG YOLK. After 21 days of incubation, the embryo is fully developed before hatching.
Enzymes that are part of the restriction-modification systems. They catalyze the endonucleolytic cleavage of DNA sequences which lack the species-specific methylation pattern in the host cell's DNA. Cleavage yields random or specific double-stranded fragments with terminal 5'-phosphates. The function of restriction enzymes is to destroy any foreign DNA that invades the host cell. Most have been studied in bacterial systems, but a few have been found in eukaryotic organisms. They are also used as tools for the systematic dissection and mapping of chromosomes, in the determination of base sequences of DNAs, and have made it possible to splice and recombine genes from one organism into the genome of another. EC 3.21.1.
The parts of a macromolecule that directly participate in its specific combination with another molecule.
Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.
The rate dynamics in chemical or physical systems.
Within a eukaryotic cell, a membrane-limited body which contains chromosomes and one or more nucleoli (CELL NUCLEOLUS). The nuclear membrane consists of a double unit-type membrane which is perforated by a number of pores; the outermost membrane is continuous with the ENDOPLASMIC RETICULUM. A cell may contain more than one nucleus. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.
The sum of the weight of all the atoms in a molecule.
The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.
The sequential correspondence of nucleotides in one nucleic acid molecule with those of another nucleic acid molecule. Sequence homology is an indication of the genetic relatedness of different organisms and gene function.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.
Antibodies produced by a single clone of cells.
An infant during the first month after birth.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells.
Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.
The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.
The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).

Multicenter comparison of the digene hybrid capture CMV DNA assay (version 2.0), the pp65 antigenemia assay, and cell culture for detection of cytomegalovirus viremia. (1/1221)

We compared the Digene Hybrid Capture CMV DNA Assay version 2.0, the pp65 antigenemia assay, traditional tube culture, and shell vial culture for the detection of cytomegalovirus (CMV) viremia in several patient populations at three centers. Of 561 blood specimens collected from 402 patients, complete clinical and laboratory data were available for 489. Using consensus definitions for true positives and true negatives, the sensitivities of the Hybrid Capture assay, antigenemia, shell vial, and tube culture were 95, 94, 43, and 46%, respectively. The specificities of the Hybrid Capture assay and antigenemia were 95 and 94%, respectively. At all three study sites, the detected level of CMV viremia was significantly higher with the Hybrid Capture assay or antigenemia than with shell vial and tube culture. In a group of 131 healthy nonimmunosuppressed volunteers, the Hybrid Capture assay demonstrated a specificity of over 99%. The Hybrid Capture assay is a standardized assay that is simple to perform and can utilize whole blood specimens that have been stored for up to 48 h. The high sensitivity and specificity of the Hybrid Capture assay along with its simplicity and flexibility make it a clinically useful assay for the detection of CMV viremia in immunocompromised or immunosuppressed patients. Further evaluation to determine its role in predicting CMV disease and for monitoring the therapeutic response to anti-CMV therapy is needed.  (+info)

Comparison of levels of human immunodeficiency virus type 1 RNA in plasma as measured by the NucliSens nucleic acid sequence-based amplification and Quantiplex branched-DNA assays. (2/1221)

This study compared levels of human immunodeficiency virus type 1 RNA in plasma as measured by the Quantiplex branched-DNA and NucliSens nucleic acid sequence-based amplification assays. RNA was detectable in 118 of 184 samples (64.13%) by the Quantiplex assay and in 171 of 184 samples (92.94%) by the NucliSens assay. Regression analysis indicated that a linear relationship existed between the two sets of values (P < 0.0001), although the Quantiplex and NucliSens values were significantly different (P < 0.001), with the NucliSens values being approximately 0.323 log higher. Spearman correlation analysis indicated that the overall changes in patient viral load patterns were highly correlative between the two assays: r = 0.912, P < 0.0001. The lower limits of sensitivity were determined to be approximately 100 copies/ml and 1,200 to 1,400 copies/ml for the NucliSens and Quantiplex assays, respectively.  (+info)

A double-selective tissue culture system for isolation of wild-type poliovirus from sewage applied in a long-term environmental surveillance. (3/1221)

We describe a simple, cost-efficient, double-selective method for isolation of wild-type poliovirus from sewage samples containing vaccine polioviruses and other enteroviruses, with a detection limit of 18 to 50 PFU per 1 to 2 liters of sewage. By this method we were able to process 1,700 sewage samples collected between 1991 and 1996, from which 10,472 plaques were isolated, 41 of them being identified as wild-type polioviruses.  (+info)

Milestones in the research on tobacco mosaic virus. (4/1221)

Beijerinck's (1898) recognition that the cause of tobacco mosaic disease was a novel kind of pathogen became the breakthrough which eventually led to the establishment of virology as a science. Research on this agent, tobacco mosaic virus (TMV), has continued to be at the forefront of virology for the past century. After an initial phase, in which numerous biological properties of TMV were discovered, its particles were the first shown to consist of RNA and protein, and X-ray diffraction analysis of their structure was the first of a helical nucleoprotein. In the molecular biological phase of research, TMV RNA was the first plant virus genome to be sequenced completely, its genes were found to be expressed by cotranslational particle disassembly and the use of subgenomic mRNA, and the mechanism of assembly of progeny particles from their separate parts was discovered. Molecular genetical and cell biological techniques were then used to clarify the roles and modes of action of the TMV non-structural proteins: the 126 kDa and 183 kDa replicase components and the 30 kDa cell-to-cell movement protein. Three different TMV genes were found to act as avirulence genes, eliciting hypersensitive responses controlled by specific, but different, plant genes. One of these (the N gene) was the first plant gene controlling virus resistance to be isolated and sequenced. In the biotechnological sphere, TMV has found several applications: as the first source of transgene sequences conferring virus resistance, in vaccines consisting of TMV particles genetically engineered to carry foreign epitopes, and in systems for expressing foreign genes. TMV owes much of its popularity as a research mode to the great stability and high yield of its particles. Although modern methods have much decreased the need for such properties, and TMV may have a less dominant role in the future, it continues to occupy a prominent position in both fundamental and applied research.  (+info)

Beijerinck's work on tobacco mosaic virus: historical context and legacy. (5/1221)

Beijerinck's entirely new concept, launched in 1898, of a filterable contagium vivum fluidum which multiplied in close association with the host's metabolism and was distributed in phloem vessels together with plant nutrients, did not match the then prevailing bacteriological germ theory. At the time, tools and concepts to handle such a new kind of agent (the viruses) were non-existent. Beijerinck's novel idea, therefore, did not revolutionize biological science or immediately alter human understanding of contagious diseases. That is how bacteriological dogma persisted, as voiced by Loeffler and Frosch when showing the filterability of an animal virus (1898), and especially by Ivanovsky who had already in 1892 detected filterability of the agent of tobacco mosaic but kept looking for a microbe and finally (1903) claimed its multiplication in an artificial medium. The dogma was also strongly advocated by Roux in 1903 when writing the first review on viruses, which he named 'so-called "invisible" microbes', unwittingly including the agent of bovine pleuropneumonia, only much later proved to be caused by a mycoplasma. In 1904, Baur was the first to advocate strongly the chemical view of viruses. But uncertainty about the true nature of viruses, with their similarities to enzymes and genes, continued until the 1930s when at long last tobacco mosaic virus particles were isolated as an enzyme-like protein (1935), soon to be better characterized as a nucleoprotein (1937). Physicochemical virus studies were a key element in triggering molecular biology which was to provide further means to reveal the true nature of viruses 'at the threshold of life'. Beijerinck's 1898 vision was not appreciated or verified during his lifetime. But Beijerinck already had a clear notion of the mechanism behind the phenomena he observed. Developments in virology and molecular biology since 1935 indicate how close Beijerinck (and even Mayer, Beijerinck's predecessor in research on tobacco mosaic) had been to the mark. The history of research on tobacco mosaic and the commitments of Mayer, Beijerinck and others demonstrate that progress in science is not only a matter of mere technology but of philosophy as well. Raemaekers' Mayer cartoon, inspired by Beijerinck, artistically represents the crucial question about the reliability of our images of reality, and about the scope of our technological interference with nature.  (+info)

Burnet Oration: living in the Burnet lineage. (6/1221)

Scientific discoveries are not made in isolation. Innovation depends on resources, both intellectual and physical. A primary requirement is the development and maintenance of appropriate institutions. Such structures do not emerge by chance, but arise from opportunity, political will and the continued efforts and commitment of many people over long periods. Suitable buildings, laboratories and state-of-the-art equipment are obviously necessary, but hardware alone is of little value in the absence of a vibrant research culture. The key characteristics of the latter are intellectual foment, open debate and a body of wisdom and knowledge about the particular subject area. Rolf Zinkernagel and 1 played a part in triggering a paradigm shift in the understanding of T cell recognition, a contribution recognized by the 1996 Nobel Prize for Physiology or Medicine. In our Nobel lectures, we both discussed briefly why it was that the John Curtin School of Medical Research (JCSMR) of 1973-75 provided a milieu that facilitated the emergence of the underlying experiments and ideas. My intention here is to discuss in more detail the scientific lineages that put this physical and intellectual environment in place, focusing particularly on the influence of Sir Frank Macfarlane (Sir Mac) Burnet as we celebrate his centenary year.  (+info)

Effect of multiple freeze-thaw cycles on hepatitis B virus DNA and hepatitis C virus RNA quantification as measured with branched-DNA technology. (7/1221)

Quantification of hepatitis B virus (HBV) DNA and hepatitis C virus (HCV) RNA often is performed in specimens that have been frozen and thawed more than once. To ensure optimal therapeutic and prognostic value, it is important to establish whether viral load measurements are affected by repeated freeze-thaw (FT) cycles. We therefore evaluated the effect of multiple FT cycles on HBV DNA and HCV RNA quantification by testing serum specimens subjected to one (baseline), two, four, and eight FT cycles with the appropriate Chiron Quantiplex assay. Linear regression analysis showed minor increases of 1.7% per FT cycle for both HBV DNA and HCV RNA. The rise in HCV RNA levels was more pronounced among low-concentration samples, since further analysis revealed an increase of 3.2% per FT cycle among samples with 0.2 to 3.86 Meq of HCV RNA per ml. Given that the coefficient of variation for the Quantiplex assays is generally 10 to 15%, the minor increases in HBV DNA and HCV RNA levels with progressive FT cycles for the specimens tested were recognized only because analysis of variance revealed a statistically significant trend (P < 0.05). Due to the minor statistical trend, the clinical impact for individual patient specimens is likely to be limited, but it may deserve further study. In conclusion, the concentration of HBV DNA and HCV RNA in serum specimens subjected to up to eight short-term FT cycles was stable.  (+info)

Direct Epstein-Barr virus (EBV) typing on peripheral blood mononuclear cells: no association between EBV type 2 infection or superinfection and the development of acquired immunodeficiency syndrome-related non-Hodgkin's lymphoma. (8/1221)

In the literature, a correlation has been suggested between the occurrence of acquired immunodeficiency syndrome (AIDS)-related non-Hodgkin's lymphomas (NHL) and Epstein-Barr virus (EBV) type 2 infection. To further investigate a possible role for EBV type 2 infection in the development of AIDS-NHL, we developed a sensitive and type-specific nested polymerase chain reaction (PCR) assay and analyzed EBV types directly on peripheral blood mononuclear cells (PBMC) in three subgroups of human immunodeficiency virus (HIV)-1 infected individuals: 30 AIDS-NHL patients, 42 individuals progressing to AIDS without lymphoma (PROG), either developing opportunistic infections (AIDS-OI) or Kaposi's sarcoma (AIDS-KS), and 18 long-term asymptomatic individuals (LTA). Furthermore, EBV type analysis was performed on PBMC samples obtained from AIDS-NHL patients in the course of HIV-1 infection. The results showed that: (1) direct analysis of PBMC is superior to analysis of B-lymphoblastoid cell lines (B-LCL) grown from the same PBMC samples; (2) in HIV-1 infected individuals, there is a high prevalence of EBV type 2 infection (50% in LTA, 62% in progressors, and 53% in AIDS-NHL) and superinfection with both type 1 and 2 (24% in LTA, 40% in progressors, and 47% in AIDS-NHL); (3) EBV type 2 (super)infection is not associated with an increased risk for development of AIDS-NHL; (4) type 2 infection can be found early in HIV-1 infection, and neither type 2 infection nor superinfection correlates with a failing immune system.  (+info)

Principles and Practice of Clinical Virology is the bible for all working in the field of clinical virology - from the trainee to the expert because theres always something new to learn.
The Stanford Clinical Virology Laboratory has deployed an in-house diagnostic test for the virus that causes COVID-19. Rapid identification of infected people could help limit the spread of the virus.. The test is being used for patients at Stanford Health Care and Stanford Childrens Health suspected of being infected with the respiratory virus SARS-CoV-2, which is spreading globally after being first identified in Wuhan, a city in China, late last year. It is expected to deliver results within 12-24 hours.. As with all currently available tests, its not yet clear how long a person needs to be infected before testing positive, or whether someone whos infected could be identified by the test before displaying symptoms.. .... ...
After 8 years and over 3000 summaries of virology publications, the executive committee have decided to discontinue the journal watch pages.. I hope my short summaries of each weeks 10 key publications have been helpful over the years, particularly in the past 6 months where I have focused almost exclusively on COVID-19 content. It has certainly been very helpful for me in keeping up with my virology reading, even after broadening out my work to global health and then policy.. I wish the UK Clinical Virology Network community all the best for the future and please contact me if you have findings or thoughts to feed into my day job.. Grant Hill-Cawthorne. ...
Lee, VJ; Yap, J; Maurer-Stroh, S; Lee, RT; Eisenhaber, F; Tay, JK; Ting, PJ; Loh, JP; Wong, CW; Tan, BH; +3 more... (2010) Investigation of causes of oseltamivir chemoprophylaxis failures during influenza A (H1N1-2009) outbreaks. Journal of clinical virology , 50 (2). pp. 104-8. ISSN 1386-6532 DOI: 10.1016/j.jcv.2010.10.004 Full text not available from this repository ...
The European Society for Clinical Virology (ESCV) is the successor of the European Group for Rapid Viral Diagnosis (EGRVD) and the European Associatio...
Citation Machine™ helps students and professionals properly credit the information that they use. Cite your newsgroup in Journal of Clinical Virology format for free.
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Electives for senior residents are customized with the Rotation and Program Director depending on the residents learning objectives which may range from learning general microbiology in greater detail or pursuing an advanced clinical research project in a specific area of microbiology. ...
Committed to covering all areas within virology research, Virology Journal accepts manuscripts from basic, clinical and translational research on the viruses ...
Of all the historic cities in Europe, Dublin may be the one thats most closely in touch with its own history. The city was founded by Viking invaders as a trading post (the Vikings understood the important of controlling ports and trade). Most modern day Irish are in some way genetically related to the Vikings. There, we saved you the cost of a DNA test. The city has undergone quite a few modernizations over the past ten years. The city has Google and Yahoo offices, which has led to some truly astounding modern architecture ...
Non-Member , $100. Webinar Description. Speaker:. Steve Miller, MD, PhD. UCSF Clinical Microbiology Laboratory, San Francisco, CA. This webinar will provide an overview of the current clinical uses and issues involved in monitoring for viral infections in transplant patients. It will describe clinical scenarios and monitoring strategies for several transplant viruses, including CMV, HSV, EBV, BK, adenovirus and HHV6.. Upon completion of the webinar, the participant should be able to: ...
The next ESCV Workshop will be on Viral Hepatitis, 29-30 May 2018 in Copenhagen, Denmark. The programme can be found here. Travel grants will be made available.. For application, please fill in the Form and send it to our secretariat: [email protected] ...
Technology Networks is an internationally recognised publisher that provides access to the latest scientific news, products, research, videos and posters.
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You may remove yourself from auto-renewal at any time by editing this field or by contacting Jess Warner, Administrative Director, at [email protected] PASCV follows the guidelines set by the Payment Card Industry Data Security Standard (PCI DSS). These guidelines refer to the technical and operational standards that businesses must follow to ensure that credit card data provided by cardholders is protected.. Membership Categories ...
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Clinical Virologys website has been around for nearly a dozen years. Weve been busy updated and modifying the website to improve its user experience. If you would like to contact Clinical Virology directly, you either send a letter to: Clinical ...
Introduction to Genetic Analysis 8th Edition, Anthony J.F. Griffiths, Susan R. Wessler, Richard C. Lewontin, William M. Gelbart, David T. Suzuki, Jeffrey H. Miller ...
The Virology Laboratory performs diagnostic tests for the entire HUG. These activities include viral culture, molecular tests and infectious serology.
Enterovirus infection, laboratory role in management of bloodborne viruses, virus infection in immunocompromised patients, antiviral resistance, application of NGS in diagnostic virology laboratory, clinical virology training ...
Author(s): Drew, WL | Abstract: Diagnostic virology services are increasingly available and pertinent as the number of useful antiviral agents grows. In this article, current methods of diagnosis are reviewed with special emphasis on rapid procedures. Guidelines for interpretation of cultures and other tests are provided.
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Nucleic acid detection methods have been rapidly evolving and play an important role in viral detection and quantification. One technology which emerged in the 1990s, polymerase chain reaction, better known as PCR, has established itself as a primary tool for molecular biology. In fact, this technology has been so widely adopted in the clinical virology laboratory it has, in many cases, completely replaced culture. At its core, PCR is a straightforward chemical reaction whereby one strand of template DNA is exponentially amplified. This chapter will give an overview of different PCR technologies available, as well as the strength and weaknesses of each. For a more in-depth review of their applications in the clinical laboratory, the reader is directed to the appropriate chapter(s) elsewhere in this text.
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
This is the autumn part of the SDVG biannual national clinical virology conference. It brings to the attention of all those working in diagnostic virology results of research, audit, clinical cases and practical experience from peers across Scotland and often beyond. The event includes various oral presentations, and a discussion ...
Hematopathology is a focus of our lab with testing performed in coagulation genetics, genetic analysis of hematologic malignancies and evaluation of stem-cell transplant patients. We also perform several additional genetic tests including hemochromatosis and cystic fibrosis screens for adults and in conjunction with the prenatal laboratory for newborns.. Other department laboratories perform molecular testing for microorganisms. The Clinical Virology Laboratory tests for multiple viral pathogens, whereas the Clinical Microbiology Laboratory tests for M. tuberculosis, C. trachomatis, and N. gonorrhoeae. The Molecular Diagnostics Laboratory complements these tests by performing in situ hybridization and quantitative PCR to assay for Epstein-Barr virus and supports the 16S ribosomal RNA DNA sequencing test to identify bacteria.. ...
Then you can get an idea, potentially, of when he was infected, how long his incubation period was, and also then evaluate who may have been exposed to him over that time frame, said Benjamin Pinsky, medical director of the clinical virology laboratory at Stanford Health Care. While there is considerable variability between cases, he said, Trump was most likely infectious several days before he tested positive - a period during which he traveled and had close contact with dozens of people.. ...
Multi-centre field evaluation of the performance of the Trinity Biotech Uni-Gold HIV 1/2 rapid test as a first-line screening assay for gay and bisexual men compared with 4th generation laboratory immunoassays, Journal Of Clinical Virology, vol.86, N/A, 2017,pp 46-51 ...
Elin Andersson is working as researcher in Department of Infectious Diseases, Section for Clinical Virology, University of Gothenburg, Sweden. Her research area ..
Creager, H. M., Cabrera, B., Schnaubelt, A., Cox, J. L., Cushman-Vokoun, A. M., Shakir, S. M., Tardif, K. D., Huang, M. L., Jerome, K. R., Greninger, A. L., Drobysheva, D., Spaulding, U., Rogatcheva, M., Bourzac, K. M., Hinrichs, S. H., Broadhurst, M. J. & Fey, P. D., Aug 2020, In : Journal of Clinical Virology. 129, 104538.. Research output: Contribution to journal › Article ...
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All the Virology on the WWW seeks to be the best single site for Virology information on the Internet. We have collected all the virology related Web sites that might be of interest to our fellow virologists, and others interested in learning more...
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Time Allowed: 3 hours Total Marks: 70, Passing Marks (35) Q.1: Choose the correct one. (14). Mark the following statements either as True or False. 1) For RT…
Introduction to Genetic Analysis 8th Edition, Anthony J.F. Griffiths, Susan R. Wessler, Richard C. Lewontin, William M. Gelbart, David T. Suzuki, Jeffrey H. Miller ...
Fields Virology is the authoritative reference book for virology, providing definitive coverage of all aspects of virology, including thorough coverage of virus biology as well as replication and medical aspects of specific virus families. With the regular outbreaks of influenza, noroviruses as well as other emerging and re-emerging viruses it is essential to have the most up-to-date information available ...
A 1 ECTS course focusing on molecular and marine virology will be held 21-23 August in Smögen, prior to the Smögen Symposium on Virology (24-26 August). The aim of the course is to provide a broad and in-depth knowledge of different areas of virology. Senior Swedish and international researchers will give lectures spanning a wide array of fields, such as marine virology, pathogenesis, evolution, emerging viruses and new antiviral therapies. The course will also include poster sessions where participants can communicate their research, time for group discussions and networking activities. Reduced registration fee for NDPIA members: ...
The Duke Center for Virology sponsors a number of activities to support virology research and the virology research community at Duke, including monthly journal clubs, happy hours and works in progress meetings; annual symposia; and periodic Distinguished Virologist lectures. We also offer travel grants to support grad students and postdocs who are presenting their research at conferences.. ...
Viruses are the most numerous entities on Earth and have also been central to many episodes in the history of humankind. As the study of viruses progresses further and further, there are several limitations in transferring this knowledge to undergraduate and high school students. This deficiency is due to the difficulty in designing hands-on lessons that allow students to better absorb content, given limited financial resources and facilities, as well as the difficulty of exploiting viral particles, due to their small dimensions. The development of tools for teaching virology is important to encourage educators to expand on the covered topics and connect them to recent findings. Discoveries, such as giant DNA viruses, have provided an opportunity to explore aspects of viral particles in ways never seen before. Coupling these novel findings with techniques already explored by classical virology, including visualization of cytopathic effects on permissive cells, may represent a new way for teaching
Dont be fooled by the stark appearance of this website (and dont get too distracted by the pulsating orb-virus particle?-that appears at the top of the homepage). Wongs Virology offers much more than it initially appears, including background information on virology topics like viral replication, viral immunology, and vaccines. The Individual Viruses page is teeming with information about, well, individual viruses (go figure). Containing information about 31 separate viruses/groups of viruses, this page is a great resource if youre looking to brush up on, say, adenoviruses or hantaviruses. As Dr. Wong, a medical virologist, is
The American Society for Virology promotes exchange of information and stimulates discussion and collaboration among virologists.. Learn More Join ASV ...
The American Society for Virology promotes exchange of information and stimulates discussion and collaboration among virologists.. Learn More Join ASV ...
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Rotation: Microbiology. Duration: Eight weeks as part of the Clinical Pathology core experience for Anatomic Pathology (AP)/Clinical Pathology (CP) or CP-only residents. One to six months (typically two to four weeks) as elective for senior residents. When: Eight weeks in PGY-2 for AP/CP residents or PGY-1 for CP-only residents (core rotation). One additional month of elective experience in PGY-3 (CP-only residents) or PGY-3-4 (AP/CP residents).. ...
Training and education are part of our key activities. Basic virology courses to students of Medicine, Dentistry, and Health biosciences are offered in collaboration with Medical Microbiology and Immunology. Virology has been a very popular venue for masters studies in biosciences. Our special selective courses Molecular Virology and Clinical Virology are regularly available for doctoral students, specialist trainees, and to others interested in advanced virology studies. Our research groups provide suitable study projects for doctoral and postdoctoral trainees. Virology contributes to postgraduate and professional training in many national and international meetings, courses, and symposia. The Department of Virology is regularly involved in organizing international virological meetings and symposia, and our senior investigators act as experts in many international organizations. At Virology it is possible to get specialist training in Clinical Microbiology and Hospital Microbiology ...
Med Virology - Lecture notes All lectures. Color. Introduction to Virology Viruses contribute significantly to the global burden of infectious disease. Template 12448 The Virology PowerPoint Template is a presentation for study of viruses. prion diseases, pestivirus, arterivirus, etc). Eight months after the SARS-CoV-2 pandemic began in Washington the UW Medicine Clinical Virology Lab processed its 1 millionth COVID-19 specimen. 2. A new class is starting at virology blog: Virology 101. 1-340 (2006) View all volumes. Virusoids are nucleic acids that depend on cells and helper viruses for packaging their nucleic acids into virus-like particles.Viroids are naked, cyclical, mostly double-strand small RNAs that appear to be restricted to plants, spread from cell to cell, and are replicated by cellular RNA polymerase II. Search free templates! The PowerPoint templates of Virology display various shapes and graphics related to viruses and scientific discoveries. 1-368 (2006) Volume 15. pp. Recognizing ...
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The journal is committed in making it easier for people to share and build upon the work of others while maintaining consistency with the rules of copyright. In order to use the Open Access paradigm to the maximum extent in true terms as free of charge online access along with usage right, we grant usage rights through the use of specific Creative Commons license.. All the journal of HSPC follow Creative Commons license [CC BY 4.0].. With this license, the authors are allowed that after publishing with the journal, they can share their research by posting a free draft copy of their article to any repository or website. Compliance CC BY license helps in:. ...
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TY - GEN. T1 - AI-based AMD Analysis. T2 - 14th Asian Conference on Computer Vision, ACCV 2018. AU - Burlina, P.. AU - Joshi, N.. AU - Bressler, N. M.. PY - 2019. Y1 - 2019. N2 - Since 2016 much progress has been made in the automatic analysis of age related macular degeneration (AMD). Much of it was dedicated to the classification of referable vs. non-referable AMD, fine-grained AMD severity classification, and assessing the five-year risk of progression to the severe form of AMD. Here we review these developments, the main tasks that were addressed, and the main methods that were carried out.. AB - Since 2016 much progress has been made in the automatic analysis of age related macular degeneration (AMD). Much of it was dedicated to the classification of referable vs. non-referable AMD, fine-grained AMD severity classification, and assessing the five-year risk of progression to the severe form of AMD. Here we review these developments, the main tasks that were addressed, and the main methods ...
Martineaus Beijerink is considered the father of virology. Write Your Answer. … Virus is derived from Latin word which means - Poison/ Venom/Slimy liquid Study of Plant viruses and virus like pathogens is called - Plant Virology HISTORY:- 1886 - Adolf Mayer (Germany)- Coined the term Mosaic He thought that the causal … Post Your Answer. Father microbiology, virology, infectious diseases. ), Concepts in Virology-From Ivanovsky to the Present [Harwood, 1993]; (5) Hilary Koprowski and Michael Oldstones book, Microbe Hunters-Then and Now [Medi-Ed Press, 1996]; (6) Charles Calisher and Marian Horzineks (eds.) virology from ivanovsky to the present sep 13 2020 posted by j k rowling ltd text id 35012404 online pdf ebook epub library devoted curiosity the book presents the first account of the joint us russian effort to sequence ivanovsky to the present concepts in virology from ivanovsky to the present free pdf concepts in virology concepts in virology from ivanovsky to the present sep 10 2020 ...
Yu Qin, Hongyun Zhang, Natalia Marlowe, Mandong Fei, Judy Yu, Xiaoqin Lei, Lulu Yu, Jia Zhang, Di Cao, Li Ma, Wen Chen, Evaluation of human papillomavirus detection by Abbott m2000 system on samples collected by FTA Elute™ Card in a Chinese HIV-1 positive population, Journal of Clinical Virology, 2016, 85, ...
Doria, If you have a pure virus prep, maybe you could titrate it (to get PFU/mL value), and then extract viral DNA and estimate the number of viral particles based on the amount of viral DNA present, knowing that parvoviruses have a single-stranded DNA genome about 5.2 kbp in size? Just a thought... Magda -----Original Message----- From: virology-bounces from oat.bio.indiana.edu [mailto:virology-bounces from oat.bio.indiana.edu] On Behalf Of virology-request from oat.bio.indiana.edu Sent: Thursday, 8 May 2008 5:04 a.m. To: virology from magpie.bio.indiana.edu Subject: Virology Digest, Vol 29, Issue 1 Send Virology mailing list submissions to virology from net.bio.net To subscribe or unsubscribe via the World Wide Web, visit http://www.bio.net/biomail/listinfo/virology or, via email, send a message with subject or body help to virology-request from net.bio.net You can reach the person managing the list at virology-owner from net.bio.net When replying, please edit your Subject line so it is more ...
Global spread of different recombinants is increasing, studies suggest, particularly in countries and regions with high levels of immigration. HIV is an extremely dynamic and variable virus, Patrik Medstrand, professor of Clinical Virology at Lund University, explained. New subtypes and recombinant forms of HIV-1 have been introduced to our part of the world, and it is highly likely that there are a large number of circulating recombinants of which we know little or nothing. We therefore need to be aware of how the HIV-1 epidemic changes over time.. The trend in areas of high population flows is toward a mixed and complex HIV flora, a marked change from the earliest days of the epidemic, when only a small number of non-recombinant variants of the virus were most prevalent. Of the two major types of the virus, HIV-1 and HIV-2 are similar in the way they are transmitted, but HIV-1 is the cause of the worldwide pandemic while HIV-2 is found in West Africa but rarely elsewhere. The period ...
Thanks to Greg Folkers for tweeting the link to a very interesting report in the Journal of Clinical Virology: Serologic assay for avian-origin influenza A (H7N9) virus in adults of Shanghai, Guangzhou and Yunnan, China. The abstract: Background and objective...
Eligible candidates are invited for a walk-in-interview for recruitment of following posts in the SVIMS Microbiology department, virology laboratory established under the DHR/ICMR VIRUS RESEARCH AND DIAGNOSTIC LABORATORY NETWORK FOR MANAGING EPIDEMICS AND NATURAL CALAMITIES on 04.04.2015 at 11 AM in Committee Hall, SVIMS, Tirupati. The engagement will be made purely on temporary basis for a period of one year and it can be terminated at any time without notice or without assigning any reason thereof by the Nodal officer the Virology Laboratory. The person engaged shall not be entitled for any claim implicit or explicit for absorption in the University.. ...
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Diagnostic and epidemiologic virology laboratories have in large part traded conventional techniques of virus detection and identification for more rapid, novel, and sensitive molecular methods. By doing so, useful phenotypic characteristics are not being determined. We feel that the impact of this shift in emphasis has impaired studies of the biology of viruses. This position paper is a plea to the scientific and administrative communities to reconsider the importance of such information. We also suggest a revised paradigm for virus isolation and characterization and provide a rationale for accumulating biologic (phenotypic) information ...
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The Laboratory Virology and Serology Reporting Scheme, the national surveillance scheme for virology and serology laboratory results has just undergone a detailed review. This editorial published in Communicable Diseases Intelligence Volume 26, No 3, September 2002 comments on the report of that review.
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Virology[edit]. Lassa virus is a member of the Arenavirida family of viruses.[7] Specifically it is an old world arenavirus, ... "Virology Journal. 10: 124. doi:10.1186/1743-422X-10-123. PMC 3639802 . PMID 23597024. Archived from the original on 10 May 2013 ...
"Journal of Virology. 75 (21): 10118-31. doi:10.1128/JVI.75.21.10118-10131.2001. PMC 114586. PMID 11581380.. ... "Journal of Virology. 87 (24): 13878-88. doi:10.1128/JVI.02666-13. PMC 3838294. PMID 24131709.. ... "Journal of Virology. 88 (20): 11644-7. doi:10.1128/JVI.01432-14. PMC 4178719. PMID 25078691.. ... "Journal of Virology. 88 (5): 2414-25. doi:10.1128/JVI.02716-13. PMC 3958092. PMID 24335291.. ...
Virology. Variola is a large brick-shaped virus measuring approximately 302 to 350 nanometers by 244 to 270 nm,[41] with a ... eds.). Fields Virology. Vol 2 (5th ed.). Philadelphia, PA: Lippincott-Raven. pp. 2905-46. ISBN 978-0-7817-6060-7. .. ... eds.). Fields Virology. Vol 2 (5th ed.). Philadelphia, PA: Lippincott-Raven. pp. 2947-76. ISBN 978-0-7817-6060-7. .. ... and Russia's State Research Center of Virology and Biotechnology VECTOR.[110] ...
Virology[edit]. Structure and genome[edit]. Lassa viruses[12][13] are enveloped, single-stranded, bisegmented, ambisense RNA ... "Current Opinion in Virology. 2 (2): 151-6. doi:10.1016/j.coviro.2012.01.003. PMC 3758253. PMID 22482712.. ... "Journal of Virology. 75 (19): 9415-9426. doi:10.1128/JVI.75.19.9415-9426.2001. PMC 114509. PMID 11533204.. ...
"Journal of Virology. 90 (8): 3860-3872. doi:10.1128/JVI.02704-15. ISSN 1098-5514. PMC 4810545. PMID 26819309.. ... Virology[edit]. KSHV is a herpesvirus, and is a large double-stranded DNA virus with a protein covering that packages its ... "Journal of Medical Virology. 81 (8): 1422-31. doi:10.1002/jmv.21550. PMC 2755560. PMID 19551832.. ... "Journal of Medical Virology. 81 (11): 1938-44. doi:10.1002/jmv.21589. PMC 2784645. PMID 19777527.. ...
Virology 187, 368-371.. *^ a b Arimoto, M., Sato, J., Maruyama, K., Mimura, G., and Furusawa, I. (1996). Effect of chemical and ... Virology[edit]. Betanodavirus is a genus of viruses, in the family Nodaviridae. Fish serve as natural hosts. There are ...
"Archives of Virology. 155 (12): 2083-103. doi:10.1007/s00705-010-0814-x. PMC 3074192. PMID 21046175.. ... Archives of Virology Supplement, vol. 20 (Limited preview). Vienna: SpringerWienNewYork. ISBN 978-3-211-20670-6. .. ... "virology.ws. 27 September 2014. Archived from the original on 29 January 2016. Retrieved 22 January 2016.. ...
Wuhan Institute of Virology[edit]. Accidental leak[edit]. During January and February 2020, the Institute was subject to ... based at the Wuhan Institute of Virology (WIV).[1][15] The Washington Post later published an article debunking the conspiracy ... Buzzfeed News also reported on an internet meme/conspiracy theory of a link between the logo of the Wuhan Institute of Virology ... that a scientist at the Wuhan Institute of Virology created the COVID-19 strain responsible for the coronavirus outbreak. ...
Journal of Virology. 73 (10): 8696-8702. PMC 112890 . PMID 10482623. Archived (PDF) from the original on 23 January 2016.. ... Locarnini S (2004). "Molecular Virology of Hepatitis B Virus". Seminars in Liver Disease. 24: 3-10. doi:10.1055/s-2004-828672. ... Desk Encyclopedia of Human and Medical Virology. Boston: Academic Press. p. 110. ISBN 0-12-375147-0.. ... Harrison T (2009). Desk Encyclopedia of General Virology. Boston: Academic Press. p. 455. ISBN 0-12-375146-2.. ...
Virology[edit]. Classification[edit]. HEV is classified into the family Hepeviridae, which is divided in two genera, ... Reviews in Medical Virology. 27 (3): e1929. doi:10.1002/rmv.1929. ISSN 1099-1654. PMID 28318080.. ... Journal of General Virology. 95 (6): 1266-1271. doi:10.1099/vir.0.063602-0. PMID 24622580.. ... "Molecular Virology of Hepatitis E Virus". Virus Research. 161 (1): 47-58. doi:10.1016/j.virusres.2011.02.011. ISSN 0168-1702 ...
"Journal of Virology. 86 (20): 10914-10923. doi:10.1128/JVI.01555-12. ISSN 0022-538X. PMC 3457148. PMID 22875964. Archived from ...
Virology[edit]. Genome[edit]. Like all mononegaviruses, marburgvirions contain non-infectious, linear nonsegmented, single- ... "Journal of Virology. 80 (13): 6497-6516. doi:10.1128/JVI.00069-06. PMC 1488971. PMID 16775337.. ... "Archives of Virology. 155 (12): 2083-2103. doi:10.1007/s00705-010-0814-x. PMC 3074192. PMID 21046175.. .mw-parser-output cite. ... Archives of Virology Supplement, vol. 20. Vienna, Austria: SpringerWienNewYork. ISBN 978-3-211-20670-6. ...
Virology[edit]. Main article: Marburg virus. Genome[edit]. Like all monomegaviruses, marburgvirions contain non-infectious, ... "Journal of Virology. 78 (10): 5458-5465. doi:10.1128/JVI.78.10.5458-5465.2004. PMC 400370 . PMID 15113924.. ... "Journal of Virology. 80 (19): 9659-9666. doi:10.1128/JVI.00959-06. PMC 1617222 . PMID 16973570.. ... "Journal of Virology. 80 (13): 6497-6516. doi:10.1128/JVI.00069-06. PMC 1488971 . PMID 16775337.. ...
Virology[edit]. This bacteriophage has a [+] circular single-stranded DNA genome of 5386 nucleotides encoding 11 proteins.[1] ... Virology. 434 (2): 278-84. doi:10.1016/j.virol.2012.09.020. PMID 23079106.. ...
"Journal of Virology. 72 (1): 158-63. doi:10.1128/jvi.72.1.158-163.1998. PMC 109360. PMID 9420211.. ... "Journal of Virology. 83 (22): 11857-61. doi:10.1128/JVI.01005-09. PMC 2772668. PMID 19740997.. ... Young, LS (2009). Desk Encyclopedia of Human and Medical Virology. Boston: Academic Press. pp. 532-533.. ... Shannon-Lowe C, Rowe M (February 2014). "Epstein Barr virus entry; kissing and conjugation". Current Opinion in Virology. 4: 78 ...
Virology[edit]. Morphology[edit]. All members of the order have a virion structure that consists of a DNA core surrounded by an ... "Journal of Virology. 87 (12): 7140-7148. doi:10.1128/JVI.00311-13. ISSN 1098-5514. PMC 3676077. PMID 23596306.. ... "Archives of Virology. 154 (1): 171-177. doi:10.1007/s00705-008-0278-4. ISSN 1432-8798. PMC 3552636. PMID 19066710.. .mw-parser- ...
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"Journal of Virology. 87 (11): 6062-6072. doi:10.1128/JVI.00330-13. ISSN 1098-5514. PMC 3648114 . PMID 23536685.. ... Journal of General Virology. 85 (9): 2643-2650. doi:10.1099/vir.0.80077-0. PMID 15302958. Retrieved 18 March 2014.. ... "Journal of Virology. 80 (9): 4249-4263. doi:10.1128/JVI.80.9.4249-4263.2006. PMC 1472016 . PMID 16611884.. ... "Journal of Virology. 83 (20): 10515-26. doi:10.1128/JVI.00731-09. PMC 2753102 . PMID 19656879.. ...
Virology[edit]. Main article: Middle East respiratory syndrome coronavirus. MERS coronaviruses under electron microscope. ...
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Virology. 255 (1): 182-9. doi:10.1006/viro.1998.9589. PMID 10049833. Kwak YT, Ivanov D, Guo J, Nee E, Gaynor RB (1999). "Role ...
2013 journal of Virology Moshe, A.; Gorovits, R. (2012). "Virus-Induced Aggregates in Infected Cells". Viruses. 4: 2218-2232. ... "Comparative cytology of nine isolates of Cauliflower mosaic virus". 1980". Virology. 102: 381-388. doi:10.1016/0042-6822(80) ... Journal of Virology. 75 (13): 5752-61. doi:10.1128/JVI.75.13.5752-5761.2001. PMC 114291 . PMID 11390577. Wei; Kikuchi, A; ... Archives of Virology. 151 (9): 1701-12. doi:10.1007/s00705-006-0757-4. PMID 16609816. Sodeik, Beate; Doms, Robert W.; Ericsson ...
The Journal of General Virology. 72 ( Pt 8) (8): 1919-26. doi:10.1099/0022-1317-72-8-1919. PMID 1678778.. ...
"Journal of Virology. 92 (12). doi:10.1128/JVI.00515-18. PMC 5974489. PMID 29618642.. ... "Virology. 411 (2): 251-9. doi:10.1016/j.virol.2010.12.031. PMC 3053447. PMID 21247613.. ... Kim FJ, Battini JL, Manel N, Sitbon M (January 2004). "Emergence of vertebrate retroviruses and envelope capture". Virology. ...
A replicating, low molecular weight RNA". Virology. 45 (2): 411-28. doi:10.1016/0042-6822(71)90342-4. PMID 5095900.. ...
"Journal of Virology. 84 (19): 9760-74. doi:10.1128/jvi.01051-10. PMC 2937777. PMID 20660196.. ...
"Virology. 452-453 (March 2014): 175-190. doi:10.1016/j.virol.2014.01.008. PMC 4005847 . PMID 24606695.. ...
Virology. 2: 210. doi:10.3389/fmicb.2011.00210. PMC 3192317 . PMID 22016749. Lodi PJ, Ernst JA, Kuszewski J, Hickman AB, ...
1999). "Hepatitis C virus RNA polymerase and NS5A complex with a SNARE-like protein". Virology. 263 (1): 30-41. doi:10.1006/ ...
Fenner's veterinary virology. Maclachlan, Nigel James., Dubovi, Edward J., Fenner, Frank, 1914-2010. (4th ed.). Amsterdam: ... Carter, G.R.; Flores, E.F.; Wise, D.J. (2006). "Herpesviridae". A Concise Review of Veterinary Virology. Retrieved 2006-06-10. ... "Molecular characterization of the genome of duck enteritis virus". Virology. 391 (2): 151-161. doi:10.1016/j.virol.2009.06.018 ... Virology Journal. 12 (1): 198. doi:10.1186/s12985-015-0424-z. ISSN 1743-422X. Li, Yufeng; Huang, Bing; Ma, Xiuli; Wu, Jing; Li ...
Institute of Human Virology Co-signs Time to Eradicate HTLV-1: An Open Letter to WHO. Learn More about Institute of Human ... Institute of Human Virology (IHV) Will Undertake Largest HIV Survey Ever Conducted in a Single Country. $100 Million Project ... Institute of Human Virology (IHV) Awarded $12M to Combat Opioid Epidemic Through Clinical Research Trials. In partnership with ... The Institute of Human Virology (IHV) was co-founded and is directed by Robert C. Gallo, M.D., the eminent scientist who became ...
TRACK 19: Medical Virology, Clinical and Diagnostic Virology. Clinical or medical virology is the branch of medicine which more ... Clinical Virology 2018, Australia Clinical Microbiology 2018, Australia Epidemiology Summit 2018, Japan Virology Asia 2018, ... Microbiology and Virology deals with the study of microorganisms and viruses. The most focused part of virology is the study of ... Virology deals with the study of viruses their shape and structure and their daily habitual. Viral Oncology or Cancer Virology ...
For the journals, see Virology (journal) and Virology Journal.. Virology is the study of viruses - submicroscopic, parasitic ... MicrobiologyBytes: The Virology Time Machine. *Timeline of the history of virology, from the Washington University in St. Louis ... The Medical and Scientific Conceptions of Influenza, Human Virology at Stanford *^ Skloot, Rebecca (2010). The Immortal Life of ... This Week in Virology Podcast by Vincent Racaniello [1]. *Virulogy, Ton E. van den Bogaard University Maastricht, the ...
Title: Virology, Author: Christian, Name: Virology, Length: 32 pages, Page: 1, Published: 2018-05-07 ... CHAPTER 9: VIROLOGY. 39. An 8-week-old infant was admitted to the hospital with symptoms of low birth weight, jaundice, and ... Virology. Viruses are obligate intracellular parasites unable to self-replicate. Once inside living cells, viruses induce the ... 854 • CHAPTER 9: VIROLOGY. 18. Molluscum contagiosum virus is a member of the A. Adenoviruses B. Herpes viruses C. ...
Epidemiology in the Virology Laboratory. During the outbreak in 1993, definitive proof that the agent causing HPS was a novel ...
"Desk Encyclopedia of General Virology. pp. 3-5.. *^ Ackermann, H-W (2009). "History of Virology: Bacteriophages". Desk ... "Desk Encyclopedia of General Virology. p. 4.. *^ Ackermann, H-W (2009). "History of Virology: Bacteriophages". ... van der Want JP, Dijkstra J (August 2006). "A history of plant virology". Archives of Virology. 151 (8): 1467-98. doi:10.1007/ ... thoughts on three decades of interaction between Virology and the Journal of Virology". J. Virol. 73 (5): 3520-3. PMC 104123. ...
More than 100 world-renowned investigators provide encyclopedic coverage of every aspect of contemporary virology, including ... the two-volume classic Fields Virology is in its thoroughly revised, updated Fifth Edition. ... Established for 20 years as the definitive virology reference, ... Fields Virology. Knipe, Fields Virology. Editors. David Mahan ... Established for 20 years as the definitive virology reference, the two-volume classic Fields Virology is in its thoroughly ...
Poliovirus: …viruses that cause polio (poliovirus) and other diseases. (Until this time, the poliovirus could be grown only in the brains of chimpanzees or the spinal cords of monkeys.) Culturing cells on glass surfaces opened the way for diseases caused by viruses to be identified by their effects on cells…
No other area of biology has grown as fast and become as relevant over the last decade as virology. It is with no little amount ... No other area of biology has grown as fast and become as relevant over the last decade as virology. It is with no little amount ...
We provide a number of Virology Services, including viral vector production and viral detection. ... Welcome to the Molecular Virology Core at the Oregon National Primate Research Center. ... Molecular Virology Core Our mission. The MVC supports investigators through an array of specialized virology services and the ... In addition, the MVC offers user training in virology techniques, safe handling of infectious agents, and assistance in ...
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Archives of Virology. Official Journal of the Virology Division of the International Union of Microbiological Societies ISSN: ... Archives of Virology. Coverage. Volume 1 / 1940 - Volume 163 / 2018. Print ISSN. 0304-8608. Online ISSN. 1432-8798. Publisher. ... Archives of Virology is a member of the Committee on Publication Ethics (COPE). The journal applies COPEs principles of ... Archives of Virology publishes original contributions from all branches of research on viruses, virus-like agents, and virus ...
Pages in category "hu:Virology". This category contains only the following page. ... Retrieved from "https://en.wiktionary.org/w/index.php?title=Category:hu:Virology&oldid=13316725" ...
Hermann Schätzl was professor of clinical virology at the Institute for Virology at the Technical University Munich and is now ... Dietrich Falke is Professor Emeritus at the Institute for Virology at the Johannes Gutenberg University in Mainz. ... where she also directs a research department for molecular virology. ...
Retroviruses are associated with a wide range of clinical diseases, including leukemia, tumors, and acquired immunodeficiency syndrome. Human immunodeficiency virus (HIV) is an exceptionally deadly retrovirus that has caused more than 20 million deaths over the past two decades. Due to the emergence of resistant strains, it is unlikely that current drug strategies, which target individual proteins, will lead to a cure. There is a serious need for superior approaches: for example, targeting anti-viral drugs towards essential RNA-protein or protein-protein interactions. To this end, I am interested in studying the structural determinants of reverse transcription and gene translation in retroviruses like HIV, Human T-cell leukemia virus and Moloney murine leukemia virus (MLV). Although aspects of reverse transcription and gene translation have received considerable attention, understanding of RNA structures and events that promote or regulate these steps remain primitive ...
Virology 364, 214-226. Uzri, D. and Gehrke, L. The polyU/UC region of the hepatitis C 3 untranslated region is a potent ...
Virology is often thought of as being a very modern discipline, but people ha... ... Virology is the biological or medical study of viruses and viral diseases. ... Virology is the biological or medical study of viruses and viral diseases. Virology is often thought of as being a very modern ... Wuhan Institute of Virology. Viktor Zhdanov. Nuclear Localization Signal. David Baltimore. Institut Armand-Frappier. adsorption ...
Tremendous progress has been made in the fight against viral diseases and the battles still to be fought in virology are of ... Tremendous progress has been made in the fight against viral diseases and the battles still to be fought in virology are of ... The Virology Department is home to several National Reference Centers (CNRs) and WHO Collaborating Centers (WHOCCs), which ... Members of the department are involved in specialization courses in virology, offered by the Institut Pasteur, in the Institut ...
By focusing on general virology principles, current and future technologies, familiar human viruses, and the effects of these ... Essential Human Virology is written for the undergraduate level with case studies integrated into each chapter. The structure ... viruses on humans, this textbook will provide a solid foundation in virology while keeping the interest of undergraduate ... Essential Human Virology is written for the undergraduate level with case studies integrated into each chapter. The structure ...
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Analytical Chromatography Biological sample preparation for chromatography including liquid and solid phase extraction, centrifugation, rotary evaporation and speedvac concentration are available. The analytical laboratory houses high pressure liquid chromatography equipment with autosampling linked to UV, diode array and refractive index detectors as well as a Bruker ion trap mass spectrometer with electrospray and chemical ionisation.. Contact Nigel Halliday Fermentation. A combination of single and twin BIOSTAT B 1L and 2L fermentors are available for pilot and omics bacterial growth experiments. All growth parameters are computer controlled via SCADA Software (MFCS/DA, B. Braun Biotech International) enabling data acquisition, process visualisation and control as well as evaluation and data export.. Contact Miguel Cámara and Nigel Minton. Flow Cytometry. Fluorescence activated cell sorters (BeckmanCoulter Altra and MoFlo XDP) and an analysis only cytometer (Beckman Coulter FC500) are ...
... a broader discipline that still encompasses the study of virology, bacteriology, mycology, botany, and zoology. At the ... Biomedicine and Health: Virology. Introduction. Virology is a twentieth-century science that deals with viruses and viral ... published General Virology, the first major textbook devoted to the new field, and edited the journal Virology, which debuted ... Virology, 4th ed. New York: Raven Press, 1998.. Gallo, Robert. Virus Hunting. Cancer, AIDS, and the Human Retrovirus: A Story ...
Applied Virology Institute Director Leadership Team Current Projects Infrastructure Support and Give to the LKSAVI Contact ... Li Ka Shing Institute of Virology News. * Results: University of Alberta COVID-19 and other Emerging Pathogens Research Fund. ... The Applied Virology Institute helps transition nascent technologies in the life sciences sector into clinical relevance. ... Three members of the Li Ka Shing Institute of Virology are serving on the National COVID-19 Task Forces ...
The Institute of Virology was founded on the 15. April 1964 (Head of the Institute from 1964 - 1994: Prof. Dr. Dr. h.c. Rudolf ... Institute of Virology. Faculty 10 - Veterinary Medicine. of Justus Liebig University Giessen. Biomedical Research Center ... Since its foundation the Institute of Virology is working on the identification, characterization, replication and ... Since 01.04.2015 the Institute of Virology is led by Prof. Dr. Friedemann Weber. ...
... debates on current topics in virology and practical work organized by teams from the Institut Pasteur.Topics include the ... Candidates must have a good knowledge of molecular and cellular biology, as well as a level in virology training at least ... debates on current topics in virology and practical work organized by teams from the Institut Pasteur. ... related to the pathologies associated with viral infections and practical work on recent approaches and techniques in virology. ...
Posted by Liz Devitt , Categories: Infectious diseases, Virology. For the immune system to do its job in fighting off disease, ... Posted by Nicholette Zeliadt , Categories: Infectious diseases, Virology. Earlier this year, the Ebola virus popped up for the ...
PhD in Virology (f/m/diverse), with Helmholtz-Center München - German Research Center for Environmental Health (HMGU) - HMGU - ... PhD in Virology (f/m/diverse). 2018/0538. Job description. Work on metagenomic analysis of polluted viral and microbial ... PhD in Virology (f/m/diverse). Helmholtz-Center München - German Research Center for Environmental Health (HMGU) - HMGU - ... Master in virology, microbiology, molecular biology, (environmental) genomics, microbial ecology or a related field. - ...
The CCR is home to an extraordinary group of scientists and clinicians exploring the cutting-edge of cancer and HIV/AIDS research. Our scientists work on a wide spectrum of biological and biomedical problems ranging from visualizing and understanding the structure of individual genes and proteins, developing novel methods for drug discovery, to inventing biomedical devices and technology and creating innovative ways to treat patients in the NIH Clinical Center ...
Covance is one of the worlds largest and most comprehensive drug development services companies with more than 12,000 employees in 60 countries. Through its lead optimization, nonclinical, clinical and commercialization services, Covance has helped pharmaceutical and biotech companies develop one-third of all prescription medicines in the market today. ...
  • Virology is the study of viruses - submicroscopic, parasitic particles of genetic material contained in a protein coat [1] [2] - and virus-like agents. (wikipedia.org)
  • The history of virology - the scientific study of viruses and the infections they cause - began in the closing years of the 19th century. (wikipedia.org)
  • Archives of Virology publishes original contributions from all branches of research on viruses, virus-like agents, and virus infections of humans, animals, plants, insects, and bacteria. (springer.com)
  • virology, study of viruses and their role in disease. (factmonster.com)
  • By focusing on general virology principles, current and future technologies, familiar human viruses, and the effects of these viruses on humans, this textbook will provide a solid foundation in virology while keeping the interest of undergraduate students. (google.com)
  • Virology is a twentieth-century science that deals with viruses and viral diseases. (encyclopedia.com)
  • Until the 1930s the study of the obscure entities referred to as viruses was inseparable from the science of microbiology, a broader discipline that still encompasses the study of virology, bacteriology, mycology, botany, and zoology. (encyclopedia.com)
  • Since its foundation the Institute of Virology is working on the identification, characterization, replication and pathogenicity of viruses as well as virus induced diseases. (uni-giessen.de)
  • The Li Ka Shing Institute of Virology (LKSIoV) unites a consortium of world-renowned researchers to promote scientific advancements aimed at expanding our understanding of viruses and other selected pathogens, their respective disease pathogenesis, and host immune responses to such infections. (ualberta.ca)
  • Virology is a study of viruses, small parasites that are not able to reproduce by themselves, but upon infection of a susceptible cell they can direct the cell machinery to produce progeny. (news-medical.net)
  • Amsterdam, 9 April 2009 - A recent special edition of the Elsevier journal Virology , reviews the past, present, and future of the exciting field of small DNA tumor viruses. (elsevier.com)
  • Launched in 1954, Virology publishes the results of basic research in all branches of virology, including the viruses of vertebrates and invertebrates, plants, bacteria, and yeasts/fungi. (elsevier.com)
  • We are expert in classical virology, molecular biology and cellular biology approaches, and use state-of-the-art techniques ranging from single cell imaging to proteomics, RNAseq and translatomics to help us build a greater understanding of how viruses successfully subvert their host cells. (surrey.ac.uk)
  • Virology accepts submissions on major advancements in the understanding of viruses that infect bacteria, archaea, fungi, plants or animals, and strives to cover topics both basic and applied. (frontiersin.org)
  • The Molecular Virology Group in Trieste (Marcello) and the Vector Borne Group in New Delhi (Sunil) investigate the molecular characteristics of different members of the fl avivirus family, including dengue, chikungunya, zika and tick-borne encephalitis viruses. (icgeb.org)
  • Synthetic virology is a branch of virology engaged in the study and engineering of synthetic man-made viruses. (wikipedia.org)
  • Recent photos from the Wuhan Institute of Virology showed a broken seal on a freezer containing over 1000 strains of deadly viruses - including one linked to coronavirus. (news.com.au)
  • The Wuhan Institute of Virology, which keeps more than 1500 strains of deadly viruses, has drawn global controversy amid claims the novel coronavirus was leaked from the facility. (news.com.au)
  • Virology is a Specialty Section devoted to communicating cutting-edge research on Human/Animal Viruses and Phages and the interactions with their hosts. (frontiersin.org)
  • Virology is a branch of the sciences which focuses on the study of viruses and organisms which behave like viruses, such as prions and viroids. (wisegeek.com)
  • One of the primary goals of virology is classification, in which viruses are studied to determine what they are and how they work. (wisegeek.com)
  • Some viruses remain relatively static, allowing researchers to rely on the same vaccine year after year, while others quickly mutate and change, requiring the development of new vaccines and drugs so that the medical and virology community can stay ahead. (wisegeek.com)
  • It provides a broad introduction to virology, which includes the nature of viruses, the interaction of viruses with their hosts and the consequences of those interactions that lead to the diseases we see. (recordedbooks.com)
  • Since the science of virology was founded in 1898 with seminal studies on tobacco mosaic virus, viruses have played a central role in understanding how all pathogens cause disease and as tools to study the biology of the plant cell. (apsnet.org)
  • This course covers the fundamental features of virology including the structure and classification of viruses. (unb.ca)
  • The Molecular Virology Program at Yale University is a campus-wide, interdepartmental program designed to coordinate and facilitate the study of viruses and viral diseases. (yale.edu)
  • The mission of the Molecular Virology Program at Yale is to facilitate the acquisition of new insights into virus biology and cellular function through the study of viruses and to develop novel approaches to inhibit viral infection or treat viral diseases. (yale.edu)
  • With great pleasure we welcome all the participants across the World to Attend " International Conference on Clinical Microbiology, Virology and Infectious Diseases " during November 19-20, 2018 in Bucharest, Romania . (vaccineconferences.com)
  • This conference provides a firm platform for scientists, engineers, directors of various companies, industrial professionals and students in the field of microbiology, virology, infectious diseases and other related fields to share their knowledge. (vaccineconferences.com)
  • When it comes to microbiology and virology the microbes are termed as the heart for most of the pressing problems solution in world.it also represents the increasing importance of human mortality around the globe, thereby vaccine development plays an important role in terms of global health. (vaccineconferences.com)
  • Virology is considered to be a subfield of microbiology or of medicine . (wikipedia.org)
  • Susanne Modrow is professor of genetics at the Institute for Medical Microbiology and Hygiene at the University of Regensburg, where she also directs a research department for molecular virology. (springer.com)
  • Basic virology courses to students of Medicine, Dentistry, and Health biosciences are offered in collaboration with Medical Microbiology and Immunology. (utu.fi)
  • At Virology it is possible to get specialist training in Clinical Microbiology and Hospital Microbiology. (utu.fi)
  • Virology is a subfield of microbiology. (wikipedia.org)
  • Microbiology Society) Today, researchers published an in-depth look at the SARS-CoV-2 mutations that have taken place during the past year in the Journal of General Virology. (medworm.com)
  • In the era of AIDS, avian and swine influenza, and other emerging viral infections, the importance of medical virology as a co-discipline with medical microbiology is increasingly being recognised. (prospects.ac.uk)
  • Seminars of interest are sponsored by the Molecular Virology Program and other academic units of the University including the Microbiology Graduate Program. (yale.edu)
  • Prospective graduate students with an interest in virology can apply for admission to the Microbiology Track of the Combined Graduate Program in the Biological and Biomedical Sciences (BBS) at Yale. (yale.edu)
  • Also included are studies involving applied research such as diagnostic technology development, monoclonal antibody panel development, vaccine development, and antiviral drug development.Archives of Virology wishes to publish obituaries of recently deceased well-known virologists and leading figures in virology. (springer.com)
  • Archives of Virology is a member of the Committee on Publication Ethics (COPE). (springer.com)
  • Each submission to Archives of Virology is screened for plagiarism. (springer.com)
  • Crystallise an identifiable home for researchers in the field of virology, immunology, and other selected areas at the University of Alberta. (ualberta.ca)
  • The identification of the causative agent of tobacco mosaic disease as a novel pathogen by Martinus Beijerinck (1898) is now acknowledged as being the official beginning of the field of virology as a discipline distinct from bacteriology. (wikipedia.org)
  • The journal is a leading resource for current information in the field of virology. (elsevier.com)
  • The exhibit displays the rotor, information on his life and scientific career, as well as information on significant contributions of Nebraskan scientists to the field of virology. (unl.edu)
  • The department has a broad-reaching program in virology covering viral infections of animals and humans. (cornell.edu)
  • More than 100 world-renowned investigators provide encyclopedic coverage of every aspect of contemporary virology, including the pathogenesis of viral diseases and the molecular biology, replication, and clinical significance of all known virus families. (google.com)
  • Hermann Schätzl was professor of clinical virology at the Institute for Virology at the Technical University Munich and is now Wyoming Excellence Chair and professor at the University of Wyoming, departments of veterinary sciences and molecular biology. (springer.com)
  • We apply current methods of virology and molecular biology to clinical virology research and to studies of experimental disease models. (utu.fi)
  • This will be possible by bringing together the unique and complementary expertise of Prof Hetherington in stomatal physiology & plant molecular biology and Prof Foster in virology & molecular plant pathology. (bio.net)
  • Guest: Dr. Lorne Tyrrell, Founder and Director, Li Ka Shing Institute of Virology at the University of Alberta - Distinguished University Professor. (ualberta.ca)
  • The Applied Virology Institute helps transition nascent technologies in the life sciences sector into clinical relevance. (ualberta.ca)
  • The exhibit is on permanent display in the Ken Morrison Life Sciences Research Center at the University of Nebraska-Lincoln, home of the Nebraska Center for Virology. (unl.edu)
  • Through the Li Ka Shing Applied Virology Institute (LKSAVI), the LKSIoV further supports discoveries in vaccines, treatments, and diagnostic tests for viral and selected other diseases affecting humans. (ualberta.ca)
  • The inception of the Li Ka Shing Institute of Virology (LKSIoV) and the Li Ka Shing Applied Virology Institute (LKSAVI) at the University of Alberta (U of A) were made possible through the generous donation of $25 million from the Li Ka Shing (Canada) Foundation. (ualberta.ca)
  • No other area of biology has grown as fast and become as relevant over the last decade as virology. (springer.com)
  • Dr. Louten is currently an associate professor of biology at Kennesaw State University, where she has served as a Teaching Fellow and developed courses in virology, biotechnology, immunology, and cell culture techniques. (google.com)
  • The virology and biology of EBV will be reviewed here. (uptodate.com)
  • The Virology Unit at the Department of Experimental & Health Sciences (CEXS) of the Universitat Pompeu Fabra (UPF) consists of 2 research groups headed by Juana Diez (Molecular Virology) and Andreas Meyerhans (Infection Biology), respectively. (upf.edu)
  • It is a multidisciplinary research field at the intersection of virology, synthetic biology, computational biology, and DNA nanotechnology, from which it borrows and integrates its concepts and methodologies. (wikipedia.org)
  • Members of the department are involved in specialization courses in virology, offered by the Institut Pasteur , in the Institut Pasteur International Network (taught by Noël Tordo, Roberto Bruzzone, Anna-Bella Failloux, etc.) and online via a series of MOOCs ( vaccinology , innate immunity, medical entomology, etc. (pasteur.fr)
  • Nice summaries of various aspects of virology, with unique illustrations included. (merlot.org)
  • Our MSc Medical Virology course covers the medical and molecular aspects of virology, bacteriology and mycology, as well as immunity to infection and epidemiology. (prospects.ac.uk)
  • The Department of Virology is regularly involved in organizing international virological meetings and symposia, and our senior investigators act as experts in many international organizations. (utu.fi)
  • and GlaxoSmithKline, where she served as Head of Clinical Drug Discovery Virology, responsible for developing a new department as well as medical strategy, IND submissions and clinical development of small molecules and vaccines. (prnewswire.com)
  • Modern advances in virology will also be addressed such as antivirals, vaccines, prion diseases and viral ecology. (unb.ca)
  • The Institute of Human Virology (IHV) was co-founded and is directed by Robert C. Gallo, M.D. , the eminent scientist who became world famous in 1984 when he co-discovered that HIV was the cause of AIDS and developed the HIV blood test. (ihv.org)
  • Essential Human Virology is written for the undergraduate level with case studies integrated into each chapter. (google.com)
  • Journal of Clinical Virology is an international journal publishing papers on any aspect of human virology that directly pertains to virus-induced clinical conditions. (elsevier.com)
  • We employ basic virology in research projects , where we use cell culture and organotypic culture models. (utu.fi)
  • I've written many posts on basic virology, but they tend to disappear with time. (virology.ws)
  • I've also included relevant episodes of the podcast TWiV , where we discuss basic virology about once a month. (virology.ws)
  • books.google.com - Established for 20 years as the definitive virology reference, the two-volume classic Fields Virology is in its thoroughly revised, updated Fifth Edition. (google.com)
  • Did the novel coronavirus that has gripped the globe come from exotic animals in a market in Wuhan, China or from a nearby government virology lab? (torontosun.com)
  • The special topics of clinical virology research are respiratory infections, infections of the central nervous system, and infections of the immunocompromized. (utu.fi)
  • Our special selective courses Molecular Virology and Clinical Virology are regularly available for doctoral students, specialist trainees, and to others interested in advanced virology studies. (utu.fi)
  • In her new role, Janet will report to Jacques Banchereau, Ph.D., Discovery and Translational Area (DTA) Head for Inflammation and Virology, and Chief Scientific Officer at Nutley , and be responsible for driving strategy and implementation of early clinical development for the Virology DTA. (prnewswire.com)
  • The institute builds on internationally recognized virology, immunology and other expertise in human diseases, as well as infrastructure with global connections to partners such as the U.S. National Institutes of Health, the Bill and Melinda Gates Foundation, Canadian Institutes of Health Research (CIHR) and more. (ualberta.ca)
  • The exceptional virology and immunology research at the University of Alberta were one of the many solidifying reasons for the establishment of the Li Ka Shing Institute of Virology on April 23, 2010. (ualberta.ca)
  • Prominently identify the philanthropy of the Li Ka Shing Foundation with one of the world's leading centers for infectious diseases, with an emphasis on virology and immunology, leading to improved diagnosis, prevention, and treatment. (ualberta.ca)
  • Fighting viral infections that affect human health - this is the Virology Department's battle. (pasteur.fr)
  • Four and a half weeks of specialized courses on the organization and functioning of various viral genomes, as well as aspects related to the pathologies associated with viral infections and practical work on recent approaches and techniques in virology. (pasteur.fr)
  • The Institute of Virology at the University of Marburg is engaged in the research of viral infections, which are mainly characterized by the pathogen exchange between animals and humans. (uni-marburg.de)
  • In the sphere of the National Plans prepared by the Ministry of Health, the Virology Department participates in surveillance of emerging and re-emerging viral infections and over the years has acquired particular skill in Bluetongue, of which it has become an OIE Reference Laboratory. (izs.it)
  • The mission of the MVC is to provide essential virology services, reagents, specialized expertise and training to investigators in order to advance a wide array of research, with a particular focus on non-human primates (NHP). (ohsu.edu)
  • The responsibilities of Virology include research, education, and providing society with virological diagnostic services and virological expertise. (utu.fi)
  • The Li Ka Shing Institute of Virology is located in the Katz Centre for Health Research at the University of Alberta. (ualberta.ca)
  • We have been publishing the results of basic research in all branches of virology for over 60 years. (elsevier.com)
  • UW Medicine is a major contributor in 31 of the 45 subject categories evaluated, with Virology at UW coming in third in the world, and Laboratory Technology in eighth place, highlighting the prominence of UW Medicine in global research. (washington.edu)
  • NUTLEY, N.J. , March 28, 2011 /PRNewswire/ -- Roche announced today that Janet Hammond , MD, Ph.D., has joined the company as Vice President, Translational Medicine - Virology in Pharmaceutical Research and Early Development (pRED). (prnewswire.com)
  • The company is on the cutting edge of research in the areas of virology and translational medicine, and I am very excited to be able to be part of an impressive team of people who are striving to develop new approaches for the treatment of patients with infectious diseases,' said Hammond. (prnewswire.com)
  • Using the innovative Frontiers peer review, our major purpose is to accelerate scientific communication and stimulate research activity in the specialty of Virology and related areas. (frontiersin.org)
  • Research on HIV/AIDS is carried out in Trieste by the Molecular Medicine (Giacca) and Molecular Virology Groups, which investigate the molecular interactions between the virus and human cells. (icgeb.org)
  • Many governments invest heavily in virology to address issues which relate to public health, and private drug companies and research institutions are also interested in virology and its applications. (wisegeek.com)
  • You have searched for Virology Law Research Programme . (findaphd.com)
  • Veterinary Virology Conference aims to bring together leading academic scientists, researchers and research scholars to exchange and share their experiences and research results on all aspects of Veterinary Virology Conference. (waset.org)
  • The Dutch Annual Virology Symposium (DAVS) provides a platform for young and established virologists to present their research. (wur.nl)
  • The activities of the Molecular Virology Program are designed to continue this tradition and exploit these strengths by coordinating and facilitating virology research at Yale. (yale.edu)
  • This is an annual distinguished lectureship in the areas of Tumor Virology and AIDS research, sponsored by the Yale Comprehensive Cancer Center. (yale.edu)
  • The Virology Department is concerned with research into and diagnosis of the commonest and most important infections of viral origin , has a Maximum Security Unit (level 3) and is equipped with an electron microscope. (izs.it)
  • The basic molecular virology research carried out in our laboratory has also led to innovations in the field of RNA interference facilitating the development of new antiviral therapeutics and novel crop protection strategies. (helsinki.fi)
  • Martinus Beijerinck called the filtered, infectious substance a "virus" and this discovery is considered to be the beginning of virology . (wikipedia.org)
  • In addition, the MVC offers user training in virology techniques, safe handling of infectious agents, and assistance in maintaining proper compliance with local institutional biosafety requirements. (ohsu.edu)
  • Why choose Seattle Children's Infectious Diseases and Virology? (seattlechildrens.org)
  • Our Infectious Diseases and Virology team works closely with you, with each other and with your child's primary care provider to offer the best and safest care for your child. (seattlechildrens.org)
  • Dietrich Falke is Professor Emeritus at the Institute for Virology at the Johannes Gutenberg University in Mainz. (springer.com)
  • The Institute of Virology was founded on the 15. (uni-giessen.de)
  • Since 01.04.2015 the Institute of Virology is led by Prof. Dr. Friedemann Weber. (uni-giessen.de)
  • This history enticed a Li Ka Shing sponsored Institute of Virology at the U of A. (ualberta.ca)
  • The Viro Vet Diagnostik UG at the Institute of Virology is approved for the detection of antibodies against rabies virus for the import/export of dogs and cats issued by the responsible authorities of most importing countries. (uni-giessen.de)
  • The Wuhan Institute of Virology (WIV), currently one of China's two level-4 biosafety labs, is widely believed to be. (medworm.com)
  • In a recent interview, Gupta supported Dr. Robert Redfield's analysis, which postulates that SARS-CoV-2 likely originated from the Wuhan Institute of Virology. (medworm.com)
  • Dr Yuan Zhiming, the deputy head of the Wuhan Institute of Virology, hit back at the accusations in an interview with state media over the weekend. (news.com.au)
  • An aerial view shows the P4 laboratory at the Wuhan Institute of Virology in Wuhan in China's central Hubei province. (news.com.au)
  • Trump isn't the first person to talk about this and Fox isn't the first media outlet to put forward the idea of the Wuhan Institute of Virology is the source of the virus. (torontosun.com)
  • A high security animal husbandry laboratory in Bhopal and the National Institute of Virology in Pune have confirmed the outbreak of bird flu in Manipur.Further details. (rediff.com)
  • Samples of his body fluids have been sent to the National Institute of Virology, Pune, for examination. (rediff.com)
  • This was also the first chair for Virology at a German university. (uni-giessen.de)
  • The Virology Department provides a comprehensive consultant-led diagnostic and reference service to University College London Hospitals NHS Foundation Trust, the local primary care trust and GPs, other NHS Trusts and Public Health England. (uclh.nhs.uk)
  • This Week in Virology (TWiV) was started in September 2008 by Vincent Racaniello and Dick Despommier , two science Professors at Columbia University Medical Center. (asm.org)
  • The first place I heard about the idea that the virology lab may have produced the virus was from a paper written by Chinese academics from the South China University of Technology and the Wuhan University of Science and Technology. (torontosun.com)
  • The Virology Department is home to several National Reference Centers (CNRs) and WHO Collaborating Centers (WHOCCs), which enable the Institut Pasteur to help diagnose, monitor and characterize emerging diseases. (pasteur.fr)
  • The Molecular Virology Group in Trieste made important advances in our understanding of how Hepatitis C overcomes the host immune response (Cevik et al. (icgeb.org)
  • To receive news and publication updates for Advances in Virology, enter your email address in the box below. (hindawi.com)
  • The Virology Committee of the American Phytopathological Committee (APS) provides a forum for discussing issues in plant pathology that are important to plant virologists. (apsnet.org)
  • The travel award was established to facilitate student travel to the APS annual meeting so that students in plant virology would have the opportunity to present findings from their studies and interact with virologists from around the world. (apsnet.org)
  • This training includes lectures given by international scientists, thematic seminars , round tables / debates on current topics in virology and practical work organized by teams from the Institut Pasteur. (pasteur.fr)
  • All manuscripts must be submitted directly to the section Virology, where they are peer-reviewed by the Associate and Review Editors of the specialty section. (frontiersin.org)
  • The virology lab in question does perform this type of work and, as the Washington Post reported earlier this week, questions were raised by American officials about the safety of the lab back in 2018. (torontosun.com)
  • A major branch of virology is virus classification . (wikipedia.org)
  • For the journals, see Virology (journal) and Virology Journal . (wikipedia.org)
  • The Chinese government has released rare footage of inside a virology testing lab in Wuhan. (news.com.au)
  • An on-line companion to the virology textbook, Principles of Molecular Virology. (merlot.org)
  • Does anybody know where the best virology graduate program is? (wisegeek.com)
  • Virology is the biological or medical study of virus es and viral disease s. (everything2.com)
  • Virology has exploded as a field of study in the past century . (everything2.com)
  • Tremendous progress has been made in the fight against viral diseases and the battles still to be fought in virology are of utmost importance for public health, particularly with the emergence of mosquito-borne viral diseases (arboviruses), such as dengue, Zika or chikungunya. (pasteur.fr)