Ventricular fibrillation. Medical search

A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.

Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.

An electrical current applied to the HEART to terminate a disturbance of its rhythm, ARRHYTHMIAS, CARDIAC. (Stedman, 25th ed)

Cessation of heart beat or MYOCARDIAL CONTRACTION. If it is treated within a few minutes, heart arrest can be reversed in most cases to normal cardiac rhythm and effective circulation.

Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.

Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.

The artificial substitution of heart and lung action as indicated for HEART ARREST resulting from electric shock, DROWNING, respiratory arrest, or other causes. The two major components of cardiopulmonary resuscitation are artificial ventilation (RESPIRATION, ARTIFICIAL) and closed-chest CARDIAC MASSAGE.

Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.

An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).

Cardiac electrical stimulators that apply brief high-voltage electroshocks to the HEART. These stimulators are used to restore normal rhythm and contractile function in hearts of patients who are experiencing VENTRICULAR FIBRILLATION or ventricular tachycardia (TACHYCARDIA, VENTRICULAR) that is not accompanied by a palpable PULSE. Some defibrillators may also be used to correct certain noncritical dysrhythmias (called synchronized defibrillation or CARDIOVERSION), using relatively low-level discharges synchronized to the patient's ECG waveform. (UMDNS, 2003)

An impulse-conducting system composed of modified cardiac muscle, having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart.

Implantable devices which continuously monitor the electrical activity of the heart and automatically detect and terminate ventricular tachycardia (TACHYCARDIA, VENTRICULAR) and VENTRICULAR FIBRILLATION. They consist of an impulse generator, batteries, and electrodes.

Methods to induce and measure electrical activities at specific sites in the heart to diagnose and treat problems with the heart's electrical system.

Regulation of the rate of contraction of the heart muscles by an artificial pacemaker.

Removal of tissue with electrical current delivered via electrodes positioned at the distal end of a catheter. Energy sources are commonly direct current (DC-shock) or alternating current at radiofrequencies (usually 750 kHz). The technique is used most often to ablate the AV junction and/or accessory pathways in order to interrupt AV conduction and produce AV block in the treatment of various tachyarrhythmias.

An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.

Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)

Recording of regional electrophysiological information by analysis of surface potentials to give a complete picture of the effects of the currents from the heart on the body surface. It has been applied to the diagnosis of old inferior myocardial infarction, localization of the bypass pathway in Wolff-Parkinson-White syndrome, recognition of ventricular hypertrophy, estimation of the size of a myocardial infarct, and the effects of different interventions designed to reduce infarct size. The limiting factor at present is the complexity of the recording and analysis, which requires 100 or more electrodes, sophisticated instrumentation, and dedicated personnel. (Braunwald, Heart Disease, 4th ed)

An autosomal dominant defect of cardiac conduction that is characterized by an abnormal ST-segment in leads V1-V3 on the ELECTROCARDIOGRAM resembling a right BUNDLE-BRANCH BLOCK; high risk of VENTRICULAR TACHYCARDIA; or VENTRICULAR FIBRILLATION; SYNCOPAL EPISODE; and possible sudden death. This syndrome is linked to mutations of gene encoding the cardiac SODIUM CHANNEL alpha subunit.

A group of cardiac arrhythmias in which the cardiac contractions are not initiated at the SINOATRIAL NODE. They include both atrial and ventricular premature beats, and are also known as extra or ectopic heartbeats. Their frequency is increased in heart diseases.

The chambers of the heart, to which the BLOOD returns from the circulation.

The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)

The restoration to life or consciousness of one apparently dead. (Dorland, 27th ed)

The period of time following the triggering of an ACTION POTENTIAL when the CELL MEMBRANE has changed to an unexcitable state and is gradually restored to the resting (excitable) state. During the absolute refractory period no other stimulus can trigger a response. This is followed by the relative refractory period during which the cell gradually becomes more excitable and the stronger impulse that is required to illicit a response gradually lessens to that required during the resting state.

Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia.

The veins that return the oxygenated blood from the lungs to the left atrium of the heart.

Rhythmic compression of the heart by pressure applied manually over the sternum (closed heart massage) or directly to the heart through an opening in the chest wall (open heart massage). It is done to reinstate and maintain circulation. (Dorland, 28th ed)

Elements of limited time intervals, contributing to particular results or situations.

A conical fibro-serous sac surrounding the HEART and the roots of the great vessels (AORTA; VENAE CAVAE; PULMONARY ARTERY). Pericardium consists of two sacs: the outer fibrous pericardium and the inner serous pericardium. The latter consists of an outer parietal layer facing the fibrous pericardium, and an inner visceral layer (epicardium) resting next to the heart, and a pericardial cavity between these two layers.

The number of times the HEART VENTRICLES contract per unit of time, usually per minute.

The lower right and left chambers of the heart. The right ventricle pumps venous BLOOD into the LUNGS and the left ventricle pumps oxygenated blood into the systemic arterial circulation.

A class Ia antiarrhythmic drug that is structurally-related to PROCAINE.

The innermost layer of the heart, comprised of endothelial cells.

Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).

The hollow, muscular organ that maintains the circulation of the blood.

Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.

A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial ARRHYTHMIAS and TACHYCARDIAS.

Occurrence of heart arrest in an individual when there is no immediate access to medical personnel or equipment.

A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).

Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli.

The abrupt cessation of all vital bodily functions, manifested by the permanent loss of total cerebral, respiratory, and cardiovascular functions.

Rapid, irregular atrial contractions caused by a block of electrical impulse conduction in the right atrium and a reentrant wave front traveling up the inter-atrial septum and down the right atrial free wall or vice versa. Unlike ATRIAL FIBRILLATION which is caused by abnormal impulse generation, typical atrial flutter is caused by abnormal impulse conduction. As in atrial fibrillation, patients with atrial flutter cannot effectively pump blood into the lower chambers of the heart (HEART VENTRICLES).

Method in which prolonged electrocardiographic recordings are made on a portable tape recorder (Holter-type system) or solid-state device ("real-time" system), while the patient undergoes normal daily activities. It is useful in the diagnosis and management of intermittent cardiac arrhythmias and transient myocardial ischemia.

An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.

Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.

Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment.

NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).

The return of a sign, symptom, or disease after a remission.

Agents that prevent clotting.

A form of heart block in which the electrical stimulation of HEART VENTRICLES is interrupted at either one of the branches of BUNDLE OF HIS thus preventing the simultaneous depolarization of the two ventricles.

A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.

Recording the locations and measurements of electrical activity in the EPICARDIUM by placing electrodes on the surface of the heart to analyze the patterns of activation and to locate arrhythmogenic sites.

Services specifically designed, staffed, and equipped for the emergency care of patients.

A type of cardiac arrhythmia with premature contractions of the HEART VENTRICLES. It is characterized by the premature QRS complex on ECG that is of abnormal shape and great duration (generally >129 msec). It is the most common form of all cardiac arrhythmias. Premature ventricular complexes have no clinical significance except in concurrence with heart diseases.

An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.

Optical imaging techniques used for recording patterns of electrical activity in tissues by monitoring transmembrane potentials via FLUORESCENCE imaging with voltage-sensitive fluorescent dyes.

Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.

A voltage-gated sodium channel subtype that mediates the sodium ion PERMEABILITY of CARDIOMYOCYTES. Defects in the SCN5A gene, which codes for the alpha subunit of this sodium channel, are associated with a variety of CARDIAC DISEASES that result from loss of sodium channel function.

Ear-shaped appendage of either atrium of the heart. (Dorland, 28th ed)

A transient loss of consciousness and postural tone caused by diminished blood flow to the brain (i.e., BRAIN ISCHEMIA). Presyncope refers to the sensation of lightheadedness and loss of strength that precedes a syncopal event or accompanies an incomplete syncope. (From Adams et al., Principles of Neurology, 6th ed, pp367-9)

A device designed to stimulate, by electric impulses, contraction of the heart muscles. It may be temporary (external) or permanent (internal or internal-external).

A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.

Abnormally low BODY TEMPERATURE that is intentionally induced in warm-blooded animals by artificial means. In humans, mild or moderate hypothermia has been used to reduce tissue damages, particularly after cardiac or spinal cord injuries and during subsequent surgeries.

A form of ventricular pre-excitation characterized by a short PR interval and a long QRS interval with a delta wave. In this syndrome, atrial impulses are abnormally conducted to the HEART VENTRICLES via an ACCESSORY CONDUCTING PATHWAY that is located between the wall of the right or left atria and the ventricles, also known as a BUNDLE OF KENT. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated protein kinase.

Damage to the MYOCARDIUM resulting from MYOCARDIAL REPERFUSION (restoration of blood flow to ischemic areas of the HEART.) Reperfusion takes place when there is spontaneous thrombolysis, THROMBOLYTIC THERAPY, collateral flow from other coronary vascular beds, or reversal of vasospasm.

The study of the generation and behavior of electrical charges in living organisms particularly the nervous system and the effects of electricity on living organisms.

An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.

An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.

Analysis based on the mathematical function first formulated by Jean-Baptiste-Joseph Fourier in 1807. The function, known as the Fourier transform, describes the sinusoidal pattern of any fluctuating pattern in the physical world in terms of its amplitude and its phase. It has broad applications in biomedicine, e.g., analysis of the x-ray crystallography data pivotal in identifying the double helical nature of DNA and in analysis of other molecules, including viruses, and the modified back-projection algorithm universally used in computerized tomography imaging, etc. (From Segen, The Dictionary of Modern Medicine, 1992)

Injuries caused by electric currents. The concept excludes electric burns (BURNS, ELECTRIC), but includes accidental electrocution and electric shock.

The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.

Treatment process involving the injection of fluid into an organ or tissue.

Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.

A characteristic symptom complex.

Computer-assisted processing of electric, ultrasonic, or electronic signals to interpret function and activity.

Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)

Modified cardiac muscle fibers composing the terminal portion of the heart conduction system.

A sudden CARDIAC ARRHYTHMIA (e.g., VENTRICULAR FIBRILLATION) caused by a blunt, non-penetrating impact to the precordial region of chest wall. Commotio cordis often results in sudden death without prompt cardiopulmonary defibrillation.

In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.

The study of the electrical activity and characteristics of the HEART; MYOCARDIUM; and CARDIOMYOCYTES.

Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.

An adjunctive treatment for PARTIAL EPILEPSY and refractory DEPRESSION that delivers electrical impulses to the brain via the VAGUS NERVE. A battery implanted under the skin supplies the energy.

A generic expression for any tachycardia that originates above the BUNDLE OF HIS.

Spasm of the large- or medium-sized coronary arteries.

Obstruction of a blood vessel (embolism) by a blood clot (THROMBUS) in the blood stream.

Failure of equipment to perform to standard. The failure may be due to defects or improper use.

Glycosides from plants of the genus DIGITALIS. Some of these are useful as cardiotonic and anti-arrhythmia agents. Included also are semi-synthetic derivatives of the naturally occurring glycosides. The term has sometimes been used more broadly to include all CARDIAC GLYCOSIDES, but here is restricted to those related to Digitalis.

The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.

Pathological conditions involving the HEART including its structural and functional abnormalities.

Abnormally rapid heartbeats with sudden onset and cessation.

The hemodynamic and electrophysiological action of the HEART ATRIA.

A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)

A condition caused by dysfunctions related to the SINOATRIAL NODE including impulse generation (CARDIAC SINUS ARREST) and impulse conduction (SINOATRIAL EXIT BLOCK). It is characterized by persistent BRADYCARDIA, chronic ATRIAL FIBRILLATION, and failure to resume sinus rhythm following CARDIOVERSION. This syndrome can be congenital or acquired, particularly after surgical correction for heart defects.

The hemodynamic and electrophysiological action of the LEFT ATRIUM.

The hemodynamic and electrophysiological action of the HEART VENTRICLES.

Electric conductors through which electric currents enter or leave a medium, whether it be an electrolytic solution, solid, molten mass, gas, or vacuum.

Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.

The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.

An optical isomer of quinine, extracted from the bark of the CHINCHONA tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular ACTION POTENTIALS, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.

The circulation of blood through the CORONARY VESSELS of the HEART.

An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.

The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)

A type of cardiac arrhythmia with premature atrial contractions or beats caused by signals originating from ectopic atrial sites. The ectopic signals may or may not conduct to the HEART VENTRICLES. Atrial premature complexes are characterized by premature P waves on ECG which are different in configuration from the P waves generated by the normal pacemaker complex in the SINOATRIAL NODE.

Impaired conduction of cardiac impulse that can occur anywhere along the conduction pathway, such as between the SINOATRIAL NODE and the right atrium (SA block) or between atria and ventricles (AV block). Heart blocks can be classified by the duration, frequency, or completeness of conduction block. Reversibility depends on the degree of structural or functional defects.

Generally, restoration of blood supply to heart tissue which is ischemic due to decrease in normal blood supply. The decrease may result from any source including atherosclerotic obstruction, narrowing of the artery, or surgical clamping. Reperfusion can be induced to treat ischemia. Methods include chemical dissolution of an occluding thrombus, administration of vasodilator drugs, angioplasty, catheterization, and artery bypass graft surgery. However, it is thought that reperfusion can itself further damage the ischemic tissue, causing MYOCARDIAL REPERFUSION INJURY.

The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.

Ion channels that specifically allow the passage of SODIUM ions. A variety of specific sodium channel subtypes are involved in serving specialized functions such as neuronal signaling, CARDIAC MUSCLE contraction, and KIDNEY function.

An antiarrhythmic agent which exerts a potential- and frequency-dependent block of SODIUM CHANNELS.

A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.

Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.

A class of drugs that act by inhibition of sodium influx through cell membranes. Blockade of sodium channels slows the rate and amplitude of initial rapid depolarization, reduces cell excitability, and reduces conduction velocity.

A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.

The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.

Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.

Conical muscular projections from the walls of the cardiac ventricles, attached to the cusps of the atrioventricular valves by the chordae tendineae.

A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.

Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.

Surgery performed on the heart.

Use of electric potential or currents to elicit biological responses.

A calcium channel blocker that is a class IV anti-arrhythmia agent.

An amino acid formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. A rare genetic disorder, hyper-beta-alaninemia, has been reported.

A vehicle equipped for transporting patients in need of emergency care.

Contractile activity of the MYOCARDIUM.

Methods of creating machines and devices.

PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.

A constitution or condition of the body which makes the tissues react in special ways to certain extrinsic stimuli and thus tends to make the individual more than usually susceptible to certain diseases.

A specialized field of physics and engineering involved in studying the behavior and properties of light and the technology of analyzing, generating, transmitting, and manipulating ELECTROMAGNETIC RADIATION in the visible, infrared, and ultraviolet range.

OXADIAZOLES bearing an oxygen at the 5-position. They are mesoionic, with delocalized positive and negative charges.

The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.

The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.

The active sympathomimetic hormone from the ADRENAL MEDULLA. It stimulates both the alpha- and beta- adrenergic systems, causes systemic VASOCONSTRICTION and gastrointestinal relaxation, stimulates the HEART, and dilates BRONCHI and cerebral vessels. It is used in ASTHMA and CARDIAC FAILURE and to delay absorption of local ANESTHETICS.

The ENTERIC NERVOUS SYSTEM; PARASYMPATHETIC NERVOUS SYSTEM; and SYMPATHETIC NERVOUS SYSTEM taken together. Generally speaking, the autonomic nervous system regulates the internal environment during both peaceful activity and physical or emotional stress. Autonomic activity is controlled and integrated by the CENTRAL NERVOUS SYSTEM, especially the HYPOTHALAMUS and the SOLITARY NUCLEUS, which receive information relayed from VISCERAL AFFERENTS.

A paravertebral sympathetic ganglion formed by the fusion of the inferior cervical and first thoracic ganglia.

A small nodular mass of specialized muscle fibers located in the interatrial septum near the opening of the coronary sinus. It gives rise to the atrioventricular bundle of the conduction system of the heart.

The hospital unit in which patients with acute cardiac disorders receive intensive care.

A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).

Surgically placed electric conductors through which ELECTRIC STIMULATION is delivered to or electrical activity is recorded from a specific point inside the body.

A malignant form of polymorphic ventricular tachycardia that is characterized by HEART RATE between 200 and 250 beats per minute, and QRS complexes with changing amplitude and twisting of the points. The term also describes the syndrome of tachycardia with prolonged ventricular repolarization, long QT intervals exceeding 500 milliseconds or BRADYCARDIA. Torsades de pointes may be self-limited or may progress to VENTRICULAR FIBRILLATION.

Paramedical personnel trained to provide basic emergency care and life support under the supervision of physicians and/or nurses. These services may be carried out at the site of the emergency, in the ambulance, or in a health care institution.

An ergot alkaloid (ERGOT ALKALOIDS) with uterine and VASCULAR SMOOTH MUSCLE contractile properties.

A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.

System established by the World Health Organization and the International Committee on Thrombosis and Hemostasis for monitoring and reporting blood coagulation tests. Under this system, results are standardized using the International Sensitivity Index for the particular test reagent/instrument combination used.

The veins and arteries of the HEART.

Blocking of a blood vessel by an embolus which can be a blood clot or other undissolved material in the blood stream.

A species of SWINE, in the family Suidae, comprising a number of subspecies including the domestic pig Sus scrofa domestica.

A C19 norditerpenoid alkaloid (DITERPENES) from the root of ACONITUM plants. It activates VOLTAGE-GATED SODIUM CHANNELS. It has been used to induce ARRHYTHMIAS in experimental animals and it has antiinflammatory and antineuralgic properties.

Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.

A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist.

Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues using a transducer placed in the esophagus.

A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.

Electronic devices that increase the magnitude of a signal's power level or current.

A guanidinium antihypertensive agent that acts by blocking adrenergic transmission. The precise mode of action is not clear.

A synthetic pregnadiene compound with anti-aldosterone activity.

The use of freezing as a special surgical technique to destroy or excise tissue.

Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)

Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.

Impaired impulse conduction from HEART ATRIA to HEART VENTRICLES. AV block can mean delayed or completely blocked impulse conduction.

The electrical properties, characteristics of living organisms, and the processes of organisms or their parts that are involved in generating and responding to electrical charges.

A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.

A product of putrefaction. Poisonous.

The smallest difference which can be discriminated between two stimuli or one which is barely above the threshold.

The valve between the left atrium and left ventricle of the heart.

A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.

Situations or conditions requiring immediate intervention to avoid serious adverse results.

A procedure to stop the contraction of MYOCARDIUM during HEART SURGERY. It is usually achieved with the use of chemicals (CARDIOPLEGIC SOLUTIONS) or cold temperature (such as chilled perfusate).

The movement of the BLOOD as it is pumped through the CARDIOVASCULAR SYSTEM.

Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.

Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.

A form of long QT syndrome that is associated with congenital deafness. It is characterized by abnormal cardioelectrophysiology involving the VOLTAGE-GATED POTASSIUM CHANNEL. It results from mutation of KCNQ1 gene (Subtype 1 or JLN1) or the KCNE1 gene (Subtype 2 or JLN2).

Carrier of aroma of butter, vinegar, coffee, and other foods.

The continuous measurement of physiological processes, blood pressure, heart rate, renal output, reflexes, respiration, etc., in a patient or experimental animal; includes pharmacologic monitoring, the measurement of administered drugs or their metabolites in the blood, tissues, or urine.

A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research.

A congenital cardiomyopathy that is characterized by infiltration of adipose and fibrous tissue into the RIGHT VENTRICLE wall and loss of myocardial cells. Primary injuries usually are at the free wall of right ventricular and right atria resulting in ventricular and supraventricular arrhythmias.

Striated muscle cells found in the heart. They are derived from cardiac myoblasts (MYOBLASTS, CARDIAC).

A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.

Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.

Prolonged dysfunction of the myocardium after a brief episode of severe ischemia, with gradual return of contractile activity.

A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.

A 43-kDa peptide which is a member of the connexin family of gap junction proteins. Connexin 43 is a product of a gene in the alpha class of connexin genes (the alpha-1 gene). It was first isolated from mammalian heart, but is widespread in the body including the brain.

Abnormally rapid heartbeats originating from one or more automatic foci (nonsinus pacemakers) in the HEART ATRIUM but away from the SINOATRIAL NODE. Unlike the reentry mechanism, automatic tachycardia speeds up and slows down gradually. The episode is characterized by a HEART RATE between 135 to less than 200 beats per minute and lasting 30 seconds or longer.

A form of CARDIAC MUSCLE disease, characterized by left and/or right ventricular hypertrophy (HYPERTROPHY, LEFT VENTRICULAR; HYPERTROPHY, RIGHT VENTRICULAR), frequent asymmetrical involvement of the HEART SEPTUM, and normal or reduced left ventricular volume. Risk factors include HYPERTENSION; AORTIC STENOSIS; and gene MUTATION; (FAMILIAL HYPERTROPHIC CARDIOMYOPATHY).

A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)

Freedom of equipment from actual or potential hazards.

Lower than normal body temperature, especially in warm-blooded animals.

Nerve fibers which project from parasympathetic ganglia to synapses on target organs. Parasympathetic postganglionic fibers use acetylcholine as transmitter. They may also release peptide cotransmitters.

Transmission of the readings of instruments to a remote location by means of wires, radio waves, or other means. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

The 10th cranial nerve. The vagus is a mixed nerve which contains somatic afferents (from skin in back of the ear and the external auditory meatus), visceral afferents (from the pharynx, larynx, thorax, and abdomen), parasympathetic efferents (to the thorax and abdomen), and efferents to striated muscle (of the larynx and pharynx).

A vital statistic measuring or recording the rate of death from any cause in hospitalized populations.

Irregular HEART RATE caused by abnormal function of the SINOATRIAL NODE. It is characterized by a greater than 10% change between the maximum and the minimum sinus cycle length or 120 milliseconds.

Radiography of the vascular system of the heart muscle after injection of a contrast medium.

Bleeding or escape of blood from a vessel.

AMINO ALCOHOLS containing the propanolamine (NH2CH2CHOHCH2) group and its derivatives.

Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.

The use of sophisticated methods and equipment to treat cardiopulmonary arrest. Advanced Cardiac Life Support (ACLS) includes the use of specialized equipment to maintain the airway, early defibrillation and pharmacological therapy.

Site of myocardial infarction. A determinant of the cardiovascular changes induced in the cat by coronary occlusion. (1/1728)

The influence of site of acute myocardial infarction on heart rate, blood pressure, cardiac output, total peripheral resistance (TPR), cardiac rhythm, and mortality was determined in 58 anesthetized cats by occlusion of either the left anterior descending (LAD), left circumflex or right coronary artery. LAD occlusion resulted in immediate decrease in cardiac output, heart rate, and blood pressure, an increase in TPR, and cardiac rhythm changes including premature ventricular beats, ventricular tachycardia, and occasionally ventricular fibrillation. The decrease in cardiac output and increase in TPR persisted in the cats surviving a ventricular arrhythmia. In contrast, right coronary occlusion resulted in a considerably smaller decrease in cardiac output. TPR did not increase, atrioventricular condition disturbances were common, and sinus bradycardia and hypotension persisted in the cats recovering from an arrhythmia. Left circumflex ligation resulted in cardiovascular changes intermediate between those produced by occlusion of the LAD or the right coronary artery. Mortality was similar in each of the three groups. We studied the coronary artery anatomy in 12 cats. In 10, the blood supply to the sinus node was from the right coronary artery and in 2, from the left circumflex coronary artery. The atrioventricular node artery arose from the right in 9 cats, and from the left circumflex in 3. The right coronary artery was dominant in 9 cats and the left in 3. In conclusion, the site of experimental coronary occlusion in cats is a major determinant of the hemodynamic and cardiac rhythm changes occurring after acute myocardial infarction. The cardiovascular responses evoked by ligation are related in part to the anatomical distribution of the occluded artery. (+info)

Mechanism linking T-wave alternans to the genesis of cardiac fibrillation. (2/1728)

BACKGROUND: Although T-wave alternans has been closely associated with vulnerability to ventricular arrhythmias, the cellular processes underlying T-wave alternans and their role, if any, in the mechanism of reentry remain unclear. METHODS AND RESULTS: -T-wave alternans on the surface ECG was elicited in 8 Langendorff-perfused guinea pig hearts during fixed-rate pacing while action potentials were recorded simultaneously from 128 epicardial sites with voltage-sensitive dyes. Alternans of the repolarization phase of the action potential was observed above a critical threshold heart rate (HR) (209+/-46 bpm) that was significantly lower (by 57+/-36 bpm) than the HR threshold for alternation of action potential depolarization. The magnitude (range, 2.7 to 47.0 mV) and HR threshold (range, 171 to 272 bpm) of repolarization alternans varied substantially between cells across the epicardial surface. T-wave alternans on the surface ECG was explained primarily by beat-to-beat alternation in the time course of cellular repolarization. Above a critical HR, membrane repolarization alternated with the opposite phase between neighboring cells (ie, discordant alternans), creating large spatial gradients of repolarization. In the presence of discordant alternans, a small acceleration of pacing cycle length produced a characteristic sequence of events: (1) unidirectional block of an impulse propagating against steep gradients of repolarization, (2) reentrant propagation, and (3) the initiation of ventricular fibrillation. CONCLUSIONS: Repolarization alternans at the level of the single cell accounts for T-wave alternans on the surface ECG. Discordant alternans produces spatial gradients of repolarization of sufficient magnitude to cause unidirectional block and reentrant ventricular fibrillation. These data establish a mechanism linking T-wave alternans of the ECG to the pathogenesis of sudden cardiac death. (+info)

Electrocardiographic measures of ventricular repolarisation dispersion in patients with coronary artery disease susceptible to ventricular fibrillation. (3/1728)

OBJECTIVE: To study electrocardiographic measures of ventricular repolarisation dispersion in patients prone to ventricular fibrillation compared with controls matched for the extent of coronary heart disease and the use of beta blockers. DESIGN: A case-control study. SETTING: Cardiovascular laboratory of a tertiary referral centre. PATIENTS: Fifty patients with documented ventricular fibrillation not associated with acute myocardial infarction, and their controls matched for sex, age, number of diseased coronary vessels, left ventricular ejection fraction, previous myocardial infarction and its location, and the use of beta blockers. MAIN OUTCOME MEASURES: Electrocardiographic measures of QT, JT, and Tend interval dispersions in a 12 lead electrocardiogram. RESULTS: The ventricular fibrillation patients compared to controls showed increased mean (SD) QTapex dispersion (53 (18) ms v 44 (18) ms, respectively; p < 0.01) and mean (SD) Tend dispersion (46 (17) ms v 38 (15) ms, respectively; p < 0.05). CONCLUSIONS: Increased QTapex and Tend dispersions are associated with a susceptibility to ventricular fibrillation even when the extent of the coronary heart disease and use of beta blockers are taken into consideration. However, because of a considerable overlap between the groups, measures of QT dispersion assessed from a 12 lead electrocardiogram do not provide clinically useful information for identification of patients at risk of sudden cardiac death. (+info)

Differential effects of defibrillation on systemic and cardiac sympathetic activity. (4/1728)

OBJECTIVE: To assess the effect of defibrillation shocks on cardiac and circulating catecholamines. DESIGN: Prospective examination of myocardial catecholamine balance during dc shock by simultaneous determination of arterial and coronary sinus plasma concentrations. Internal countershocks (10-34 J) were applied in 30 patients after initiation of ventricular fibrillation for a routine implantable cardioverter defibrillator test. Another 10 patients were externally cardioverted (50-360 J) for atrial fibrillation. MAIN OUTCOME MEASURES: Transcardiac noradrenaline, adrenaline, and lactate gradients immediately after the shock. RESULTS: After internal shock, arterial noradrenaline increased from a mean (SD) of 263 (128) pg/ml at baseline to 370 (148) pg/ml (p = 0.001), while coronary sinus noradrenaline fell from 448 (292) to 363 (216) pg/ml (p = 0.01), reflecting a shift from cardiac net release to net uptake. After external shock delivery, there was a similar increase in arterial noradrenaline, from 260 (112) to 459 (200) pg/ml (p = 0.03), while coronary sinus noradrenaline remained unchanged. Systemic adrenaline increased 11-fold after external shock (p = 0.01), outlasting the threefold rise following internal shock (p = 0.001). In both groups, a negative transmyocardial adrenaline gradient at baseline decreased further, indicating enhanced myocardial uptake. Cardiac lactate production occurred after ventricular fibrillation and internal shock, but not after external cardioversion, so the neurohumoral changes resulted from the defibrillation process and not from alterations in oxidative metabolism. CONCLUSIONS: A dc shock induces marked systemic sympathoadrenal and sympathoneuronal activation, but attenuates cardiac sympathetic activity. This might promote the transient myocardial depression observed after electrical discharge to the heart. (+info)

Mechanisms of isoflurane-induced myocardial preconditioning in rabbits. (5/1728)

BACKGROUND: Isoflurane has cardioprotective effects that mimic the ischemic preconditioning phenomenon. Because adenosine triphosphate-sensitive potassium channels and adenosine receptors are implicated in ischemic preconditioning, the authors wanted to determine whether the preconditioning effect of isoflurane is mediated through these pathways. METHODS: Myocardial infarct size was measured in seven groups of propofol-anesthetized rabbits, each subjected to 30 min of anterolateral coronary occlusion followed by 3 h of reperfusion. Groups differed only in the pretreatments given, and controls received no pretreatment. An ischemia-preconditioned group was pretreated with 5 min of coronary occlusion and 15 min of reperfusion. An isoflurane-preconditioned group was pretreated with 15 min end-tidal isoflurane, 1.1%, and then 15 min of washout. An isoflurane-plus-glyburide group was administered 0.33 mg/kg glyburide intravenously before isoflurane pretreatment. An isoflurane plus 8-(p-sulfophenyl)-theophylline (SPT) group received 7.5 mg/kg SPT intravenously before isoflurane. Additional groups were administered identical doses of glyburide or SPT, but they were not pretreated with isoflurane. Infarct size and area at risk were defined by staining. Data were analyzed by analysis of variance or covariance. RESULTS: Infarct size, expressed as a percentage of the area at risk (IS:AR) was 30.2+/-11% (SD) in controls. Ischemic preconditioning and isoflurane preexposure reduced myocardial infarct size significantly, to 8.3+/-5% and 13.4+/-8.2% (P<0.05), respectively. Both glyburide and SPT pretreatment eliminated the preconditioning-like effect of isoflurane (IS:AR = 30.0+/-9.1% and 29.2+/-12.6%, respectively; P = not significant). Neither glyburide nor SPF alone increased infarct size (IS:AR = 33.9+/-7.6% and 31.8+/-12.7%, respectively; P = not significant). CONCLUSIONS: Glyburide and SPT abolished the preconditioning-like effects of isoflurane but did not increase infarct size when administered in the absence of isoflurane. Isoflurane-induced preconditioning and ischemia-induced preconditioning share similar mechanisms, which include activation of adenosine triphosphate-sensitive potassium channels and adenosine receptors. (+info)

Percutaneous transluminal coronary angioplasty, alone or in combination with urokinase therapy, during acute myocardial infarction. (6/1728)

To investigate the effect of pre-treatment of a thrombus with a low dose of urokinase on establishing patency in a persistent infarct-related artery (IRA) during direct percutaneous coronary angioplasty (PTCA), the frequency of acute restenosis during direct PTCA, alone, or in combination with the intracoronary administration of urokinase, was examined in a consecutive nonrandomized series of patients with acute myocardial infarction (AMI). Two hundred and seventy-two successful PTCA patients (residual stenosis <50%) were divided into 2 groups: 88 patients received pre-treatment with intracoronary urokinase following PTCA (combination group); 184 received only direct PTCA without thrombolytic therapy (PTCA group). In the present study, after achievement of a residual stenosis of less than 50%, IRA was visualized every 15 min to assess the frequency of acute restenosis, which was defined as an acute progression of IRA with more than 75% restenosis after initially successful PTCA. In the patients with a large coronary thrombus, the frequency (times) of acute restenosis was significantly lower in the combination group than in the PTCA group (0.98+/-0.19 vs 2.92+/-0.32, p<0.0001). On the other hand, in the patients with a small coronary thrombus, the frequency of acute restenosis showed no difference in either group. The present study indicates that in patients with AMI, PTCA combined with pre-treatment of a low dose of urokinase is much more effective than PTCA alone, especially for those patients who have a large coronary thrombus. (+info)

Atrial fibrillation detection and R-wave synchronization by Metrix implantable atrial defibrillator: implications for long-term efficacy and safety. The Metrix Investigators. (7/1728)

BACKGROUND: The long-term efficacy of atrial fibrillation (AF) detection and R-wave synchronization are critical safety requirements for the development of an implantable atrial defibrillator (IAD) for treatment of AF. METHODS AND RESULTS: The long-term efficacy of the Metrix IAD for AF detection and R-wave synchronization was tested in 51 patients. The mean duration of follow-up was 259+/-138 days (72 to 613 days). AF detection tests were performed 2240 times during observed operation with 100% specificity and 92.3% sensitivity for differentiation between sinus rhythm and AF; 2219 episodes and their electrograms stored in the device during AF detection were analyzed. The positive predictive value of the AF detection algorithm was 97.4% (lower 95% confidence limit [CL], 94.5%) in the out-of-hospital setting. A total of 242 435 R waves were analyzed for R-wave synchronization. Of these, 49% were marked for synchronized shock delivery, 82% of sinus rhythm and 36% of AF R waves, respectively. All shock markers were properly synchronized and within the R wave (overall synchronization accuracy, 100%; lower 95% CL, 99.999%). Overall, 3719 shocks have been delivered via the IAD with no instance of unsynchronized shock delivery or any episode of proarrhythmia. The observed proarrhythmic risk was 0%, with an estimated maximum proarrhythmic risk of 0.084% per shock (95% upper CL). CONCLUSIONS: The Metrix IAD can appropriately detect AF with a high specificity and sensitivity and reliably synchronize within a suitable R wave for shock delivery to minimize the risk of ventricular proarrhythmia. (+info)

Intracoronary flecainide induces ST alternans and reentrant arrhythmia on intact canine heart: A role of 4-aminopyridine-sensitive current. (8/1728)

BACKGROUND: The electrical alternans shown on an ST segment, ST alternans, is known as one of the most important predictors of ventricular fibrillation (VF). It has also been reported that sodium channel inhibition changes action potential configuration, especially on the repolarization phase. Thus, the sodium channel blocker may produce ST alternans and trigger reentrant arrhythmia. METHODS AND RESULTS: A sodium channel blocker (disopyramide, lidocaine, or flecainide) was infused selectively into the left anterior descending coronary artery in anesthetized, open-chest dogs. Sixty unipolar electrograms were simultaneously recorded from the entire cardiac surface of the heart. The amplitude of ST alternans (STa) was determined as the difference in the ST-segment magnitude between 2 consecutive electrograms. We accepted the greatest STa among 60 leads for evaluation. High-dose flecainide (100 microg. kg-1. min-1) increased STa and evoked a spontaneous VF. The STa in high-dose flecainide loading (8.7+/-3.4 mV; mean+/-SEM) was significantly greater than that in disopyramide or lidocaine (0. 9+/-0.4 and 0.8+/-0.2 mV, P<0.05). Treatment of 4-aminopyridine (4-AP) suppressed the increase in STa and the occurrence of VF evoked by flecainide, while E4031 or verapamil did not inhibit those. CONCLUSIONS: Flecainide caused the ST alternans that was closely correlated to the occurrence of VF. Because the ST alternans was suppressed by 4-AP treatment, a 4-AP-sensitive current such as Ito or Isus may play an important role on this phenomenon. (+info)

... is initially found in about 10% of people with cardiac arrest. Ventricular fibrillation can occur due ... MacWilliam spent many years working on ventricular fibrillation and was one of the first to show that ventricular fibrillation ... on the basis of the fact that ventricular fibrillation itself is common, idiopathic ventricular fibrillation accounts for an ... of the cases of ventricular fibrillation unrelated to myocardial infarction, and 14% of all ventricular fibrillation ...

https://en.wikipedia.org/wiki/Ventricular_fibrillation

PVF is defined as ventricular fibrillation not preceded by heart failure or shock, in contrast to secondary ventricular ... Primary ventricular fibrillation (PVF) is an unpredictable and potentially fatal arrhythmia occurring during the acute phase of ... Volpi A, Cavalli A, Santoro L, Negri E (1998). "Incidence and prognosis of early primary ventricular fibrillation in acute ... "Long Term Survival after First Myocardial Infarction is not Determined by the Occurrence of Ventricular Fibrillation in the ...

https://en.wikipedia.org/wiki/Primary_ventricular_fibrillation

"Ventricular fibrillation". Mayo Clinic. Kakita T, Hasegawa K, Morimoto T, Kaburagi S, Wada H, Sasayama S (November 1999). "p300 ... or ventricular fibrillation which is a serious condition where the ventricles of the heart aren't pumping consistently and ...

https://en.wikipedia.org/wiki/GATA5

There are two major classes of cardiac fibrillation: atrial fibrillation and ventricular fibrillation. Atrial fibrillation is ... Ventricular Fibrillation". NCBI Bookshelf. PMID 30725805. Retrieved 2019-03-29. "fibrillation" at Dorland's Medical Dictionary ... Ventricular fibrillation is an irregular and uncoordinated contraction of the cardiac muscle of ventricles. It is a common ... Krummen, David E; Ho, Gordon; Villongco, Christopher T; Hayase, Justin; Schricker, Amir A (2016). "Ventricular fibrillation: ...

https://en.wikipedia.org/wiki/Fibrillation

Remotely treating ventricular fibrillation. Medphone Corporation, 1989 Shanker A, Makhija S, Mantri PK (1982). " ...

https://en.wikipedia.org/wiki/Telehealth

All had ventricular fibrillation; six arrests occurred after the arrival of the MCCU, and four occurred shortly before arrival ... Beck, CS; Pritchard, WH; Feil, HS (1947). "Ventricular fibrillation of long duration abolished by electric shock". The Journal ... This training required 10 hours, and in the first demonstration project, survival from ventricular fibrillation increased from ... Zoll, PM; Linenthal, AJ; Gibson, W (1956). "Termination of ventricular fibrillation in man by externally applied electric ...

https://en.wikipedia.org/wiki/History_of_cardiopulmonary_resuscitation

Both ventricular fibrillation and ventricular tachycardia can result in the heart ineffectively pumping blood to the body. ... Ventricular fibrillation is a tachyarrhythmia characterized by turbulent electrical activity in the ventricular myocardium ... "Ventricular tachycardia - Symptoms and causes". Mayo Clinic. Retrieved 2021-11-29. "Ventricular fibrillation - Symptoms and ... The two shockable rhythms are ventricular fibrillation and pulseless ventricular tachycardia. In children, 2 to 4 J/Kg is ...

https://en.wikipedia.org/wiki/Cardiac_arrest

Kassap was diagnosed with ventricular fibrillation. He slowly recovered, but in May 2011 he was forced to withdraw from another ...

https://en.wikipedia.org/wiki/Danny_Kassap

... and Ventricular Fibrillation in the EP Lab. What is the Atrial Rhythm? are some of the notable ones. The Government of India ... "Ventricular Fibrillation in the EP Lab. What is the Atrial Rhythm?". Journal of Cardiovascular Electrophysiology. 19 (9): 991- ...

https://en.wikipedia.org/wiki/Tarlochan_Singh_Kler

Preventing ventricular fibrillation by flattening cardiac restitution. Proceedings of the National Academy of Sciences. Alan ... he and his colleagues Zhilin Qu and James N Weiss then demonstrated that Ventricular Fibrillation (VF), the primary cause of ... "Preventing ventricular fibrillation by flattening cardiac restitution". Proceedings of the National Academy of Sciences. 97 (11 ... "Preventing ventricular fibrillation by flattening cardiac restitution". Proceedings of the National Academy of Sciences. 97 (11 ...

https://en.wikipedia.org/wiki/Alan_Garfinkel

Syncopal Attacks Due to Paroxysmal Ventricular Fibrillation. Presentation of 1st Case in Italian Pediatric Literature]". La ... It is a relatively common cause of sudden death along with Brugada syndrome and arrhythmogenic right ventricular dysplasia. In ... When symptoms occur, they are generally caused by abnormal heart rhythms (arrhythmias), most commonly a form of ventricular ... November 2015). "2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden ...

https://en.wikipedia.org/wiki/Long_QT_syndrome

Würzel, 61, British guitarist (Motörhead), ventricular fibrillation. Pierrette Alarie, 89, Canadian soprano, wife of tenor ...

https://en.wikipedia.org/wiki/Deaths_in_July_2011

George Allen, 72, American football coach, ventricular fibrillation. Ed Gantner, 31, American professional wrestler, suicide by ...

https://en.wikipedia.org/wiki/Deaths_in_December_1990

Ventricular fibrillation is a major cause of cardiac arrest, or sudden cardiac death, which accounts for about 10% of mortality ... His investigations have been the basis for development of new markers and therapies for atrial and ventricular fibrillation. ... His investigations have been the basis for development of new markers and therapies for atrial and ventricular fibrillation. ... The same tissue was confirmed to also play a pathogenic role in ventricular fibrillation associated with myocardial infarction ...

https://en.wikipedia.org/wiki/Michel_Haïssaguerre

Fibrillation can affect the atrium (atrial fibrillation) or the ventricle (ventricular fibrillation): ventricular fibrillation ... Ventricular arrhythmias include ventricular fibrillation and ventricular tachycardia. Bradyarrhythmias are due to sinus node ... It is needed for the chaotic rhythm of ventricular fibrillation and is also used for pulseless ventricular tachycardia. Often, ... tachycardia Ventricular fibrillation Torsades de pointes Arrhythmogenic right ventricular dysplasia Re-entry ventricular ...

https://en.wikipedia.org/wiki/Arrhythmia

... can cause fibrillation. If not immediately treated by defibrillation, ventricular fibrillation is usually lethal, causing ... If ventricular fibrillation occurs (as above), the blood supply to the brain is diminished, which may cause cerebral hypoxia ( ... A sustained electric shock from AC at 120 V, 60 Hz is an especially dangerous source of ventricular fibrillation because it ... Still larger currents result in tissue damage and may trigger ventricular fibrillation or cardiac arrest. Consequences of ...

https://en.wikipedia.org/wiki/Electrical_injury

Gouaux, JL; Ashman, R (Sep 1947). "Auricular fibrillation with aberration simulating ventricular paroxysmal tachycardia". ... often seen isolated that is typically seen in atrial fibrillation. It is more often misinterpreted as a premature ventricular ... Tamburrini, LR; Fontanelli, A; Primossi, G (Feb 2001). "[Ventricular pre-excitation: electrophysiopathology, criteria for ... Atrial fibrillation Electrocardiogram Kennedy LB, Leefe W, Leslie BR (2004). "The Ashman phenomenon". J la State Med Soc. 156 ( ...

https://en.wikipedia.org/wiki/Ashman_phenomenon

Bertrix L, Timour-Chah Q, Lang J, Lakhal M, Faucon G (May 1986). "Protection against ventricular and atrial fibrillation by ... ventricular tachycardia), or very symptomatic atrial fibrillation or flutter. Due to the risk of serious side effects, the FDA ... such as atrial fibrillation) developed TdP. For patients who had a history of sustained ventricular tachycardia (abnormal ... The incidence of TdP for sustained ventricular tachycardia patients was 0% with an 80 mg daily dose, 0.5% at 160 mg, 1.6% at ...

https://en.wikipedia.org/wiki/Sotalol

Ventricular tachycardia and ventricular fibrillation can also be detected. Respiration affects the cardiac cycle by varying the ... As seen in the figure showing premature ventricular contractions (PVCs), the PPG pulse for the cardiac cycle with the PVC ... increasing ventricular preload, but decreasing stroke volume. Conversely during expiration, the heart is compressed, decreasing ...

https://en.wikipedia.org/wiki/Photoplethysmogram

Ventricular arrhythmias include ventricular fibrillation and ventricular tachycardia. Arrhythmias are due to problems with the ... The initial heart rhythm is most often ventricular fibrillation. The diagnosis is confirmed by finding no pulse. While a ... In Europe and North America, as of 2014, atrial fibrillation affects about 2% to 3% of the population. Atrial fibrillation and ... Pulmonary atresia with a ventricular septal defect: This type of pulmonary atresia happens when a ventricular septal defect ...

https://en.wikipedia.org/wiki/Cardiology

In this report, the system successfully and consistently detected and converted episodes of ventricular fibrillation that were ... O'Riordan, Michael (May 18, 2009). "Subcutaneous ICD system detects and terminates induced ventricular fibrillation". The Heart ... Of the 55 patients, 53 had two instances of fibrillation and in 52 these were successfully converted. These findings were ... One of the three patients was successfully treated for seven successive episodes of ventricular tachycardia, a condition known ...

https://en.wikipedia.org/wiki/Cameron_Health

... polymorphic ventricular tachycardia) Wide complex tachycardia Ventricular flutter Ventricular fibrillation Ventricular ... must be specified as atrial or ventricular (e.g., the ventricular rate in ventricular fibrillation is 300-600 bpm, whereas the ... Jafary, Fahim H (2007). "The "incidental" episode of ventricular fibrillation: A case report". Journal of Medical Case Reports ... Rhythm disturbances or arrhythmias: Atrial fibrillation and atrial flutter without rapid ventricular response Premature atrial ...

https://en.wikipedia.org/wiki/Electrocardiography

Tachyarrhythmias are associated with ventricular fibrillation and ventricular tachycardia. Bradyarrhythmias are associated with ... Sudden cardiac death is triggered by an electrical accident, which can be treated with ventricular defibrillation. Stroke ... with both atrial and ventricular ectopy. The sudden epileptic death may be a result of the sympathetic activation or autonomic ...

https://en.wikipedia.org/wiki/Neurocardiology

This improved response time directly related to improved survival rates for victims of SCA with ventricular fibrillation or ... of SCAs are caused by ventricular fibrillation (VF). Receiving defibrillation from an automated external defibrillator (AED) is ... pulseless ventricular tachycardia (VF/VT).: 1058 During this experiment, the survival rate for witnessed victims of SCA with VT ...

https://en.wikipedia.org/wiki/Police_vehicles_equipped_with_automated_external_defibrillators_in_North_America

13 December 1947). "Ventricular Fibrillation of Long Duration Abolished by Electric Shock". Journal of the American Medical ...

https://en.wikipedia.org/wiki/Walter_Pritchard

... the risk of sudden death due to serious abnormal heart rhythms such as ventricular fibrillation or polymorphic ventricular ... or sudden cardiac death due to serious abnormal heart rhythms such as ventricular fibrillation or polymorphic ventricular ... in those with Brugada syndrome are typically dangerous arrhythmias such as ventricular fibrillation or polymorphic ventricular ... "Ventricular fibrillation without apparent heart disease: description of six cases". American Heart Journal. 118 (6): 1203-9. ...

https://en.wikipedia.org/wiki/Brugada_syndrome

Garrett and Farelli diagnose cardiac arrest or ventricular fibrillation. Farelli earns Garrett's admiration by improvising a ...

https://en.wikipedia.org/wiki/The_Prize_(1963_film)

"Ventricular fibrillation induced by carotid sinus massage without preceding bradycardia". EP Europace. 7 (6): 638-640. doi: ... from ventricular tachycardia. Like the valsalva maneuver, it is a treatment for acute SVT. It is less effective than ...

https://en.wikipedia.org/wiki/Carotid_sinus

... prevents cocaine-induced ventricular fibrillation". Am. J. Physiol. 265 (5 Pt 2): H1529-35. PMID 8238564.[permanent dead link] ...

https://en.wikipedia.org/wiki/Cardiac_stimulant

Intermittent Ventricular Fibrillation with Complete Recovery: Report of a Case. Boston Med Surg J. 1925;193:473-475. Amberg, S ... The Prognosis of Auricular Fibrillation of Undetermined Origin. JAMA. 1941;117(5):330-332. Willius, F.A., T.J. Dry and R. ... Observations on Negativity of the Final Ventricular T-Wave of the Electrocardiogram. Am J Med Sci. 1920;160(6):844-864. ... Observations on Changes in Form of the Initial Ventricular Complex in Isolated Derivations of the Human Electrocardiogram. Arch ...

https://en.wikipedia.org/wiki/Fredrick_Arthur_Willius

427.31 Atrial fibrillation 427.32 Atrial flutter 427.4 Ventricular fibrillation and flutter 427.41 Ventricular fibrillation ... paroxysmal supraventricular 427.3 Atrial fibrillation and flutter ...

https://en.wikipedia.org/wiki/List_of_ICD-9_codes_390–459:_diseases_of_the_circulatory_system

Tumors are one cause of blood vessel compression.[citation needed] Ventricular tachycardia represents a series of irregular ... Anticoagulation with warfarin or heparin may be used if the patient has atrial fibrillation.[citation needed] Operative ... Individuals with sickle cell anemia, compressed blood vessels, ventricular tachycardia, plaque buildup in the arteries, blood ...

https://en.wikipedia.org/wiki/Brain_ischemia

... and ventricular fibrillation. The most common side effects reported by at least 2% of patients in controlled trials of ... Events reported have included coronary artery vasospasm, transient myocardial ischemia, myocardial infarction, ventricular ...

https://en.wikipedia.org/wiki/Sumatriptan

He is widely recognized for his scholarly contributions to the domains of acute coronary syndrome, left ventricular repair and ... Hannover Medical School Department of Cardiology and Angiology Interview about Atrial fibrillation (ARD 4.11. 2014, German ...

https://en.wikipedia.org/wiki/Johann_Bauersachs

Atrial fibrillation Atrial fibrillation with rapid ventricular response Atrial flutter Atrial tachycardia Bifascicular block ... Atrial septal defect Ventricular septal defect Patent ductus arteriosus and Coarctation of aorta (may cause cyanosis in some ... Catecholaminergic polymorphic ventricular tachycardia Ectopic beat (cardiac ectopy) Ectopic pacemaker (Ectopic focus) First- ...

https://en.wikipedia.org/wiki/List_of_circulatory_system_conditions

... right ventricular systolic pressure above 80 mmHg, or cardiac fibrillation. For dysfunctional artificial conduits, PPVI ... progressive right ventricular dilation, progressive right ventricular dysfunction, progressive tricuspid valve regurgitation, ... Ventricular function and size are assessed with an echocardiogram. The right ventricle and the anatomy of the outflow tract, ... PPVI can be used to repair congenital defects in the pulmonary valve or right ventricular outflow tract dysfunction, such as ...

https://en.wikipedia.org/wiki/Percutaneous_pulmonary_valve_implantation

... causing ventricular fibrillation. Some also have local anesthetic action. The analgesic effects have also been proven, by ... treatment of heart conditions such as atrial fibrillation). There are at least 86 identified bufadienolides.[clarification ...

https://en.wikipedia.org/wiki/Bufagin

This should not be confused with the catastrophic loss of heartbeat seen with ventricular fibrillation or asystole.[citation ...

https://en.wikipedia.org/wiki/Lev's_disease

Paroxysmal ventricular tachycardia and fibrillation". Chinese Medical Journal. 75 (5): 365-378. PMID 13447130. Hagan, Paul ( ...

https://en.wikipedia.org/wiki/Antimony_potassium_tartrate

The so-called 'risk factors' for embolisation, with the exception of atrial fibrillation, can be called, at best, 'scientific ... 3. For the manufacturing of cardiac ventricular chambers in an experimental artificial heart under testing in a French ... atrial fibrillation, anticoagulant treatment, previous systemic emboli, etc., and scant information about the post-operative ... its shape was anatomically contoured into two different configurations to better fit in the aortic and the atrio-ventricular ...

https://en.wikipedia.org/wiki/Pericardial_heart_valves

If it does become symptomatic, beta-blockers can be used to try and suppress ventricular ectopy. Class I and III agents are ... When the atrial rhythm is irregular (as in atrial fibrillation or sinus arrythmia) the presence of bigeminy depends on the ... The term "rule of bigeminy" is used to refer to the dependence of bigeminy on the ventricular cycle length in irregular rhythms ... The two beats are figuratively similar to two twins (hence bi- + gemini). For example, in ventricular bigeminy, a sinus beat is ...

https://en.wikipedia.org/wiki/Bigeminy

... amiodarone or digoxin for achieving ventricular rate control in patients with acute uncomplicated atrial fibrillation". Crit. ... October 2010). "Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation ... Stroke Risk in Atrial Fibrillation Working Group (2007). "Independent predictors of stroke in patients with atrial fibrillation ... 2006). "Clopidogrel plus aspirin versus oral anticoagulation for atrial fibrillation in the Atrial fibrillation Clopidogrel ...

https://en.wikipedia.org/wiki/Management_of_atrial_fibrillation

... ventricular fibrillation as well as possible risks of coagulopathy and infection. Furthermore, the timing of hypothermia ...

https://en.wikipedia.org/wiki/Skin_temperature

In the absence of isolated right ventricular failure, seen in some patients with right ventricular infarction, a positive ... The absence of 'a' waves may be seen in atrial fibrillation. An exaggerated "y" wave or diastolic collapse of the neck veins ... wave and occurs as a result of the right ventricle pulling the tricuspid valve downward during ventricular systole (ventricular ... Third degree heart block Ventricular ectopics Ventricular tachycardia Absent 'a' wave (no unifocal atrial depolarisation) ...

https://en.wikipedia.org/wiki/Jugular_venous_pressure

... bradycardia or ventricular fibrillation. In a normal heart beat rhythm, the SA node usually suppresses the ectopic pacemaker ... On an ECG, the QRS complex will be abnormally shaped when looking at ventricular ectopic activity, often it occurs earlier with ... The pacemaker that is operating in the ventricles is known as the ventricular. Other such ectopic pacemakers can even lie ... Abbott, Louise (December 2012). "Atrial Fibrillation - information, symptoms and treatment". Bupa. Port, Carol Mattson (2005). ...

https://en.wikipedia.org/wiki/Ectopic_pacemaker

... action potential duration shortening in the atria and ventricles and increased ventricular tachycardia/ventricular fibrillation ...

https://en.wikipedia.org/wiki/Transgene

... hemodynamic functions and ventricular fibrillation. F15845 was also shown to exert improved effects when the membrane potential ...

https://en.wikipedia.org/wiki/F15845

"Ventricular fibrillation of long duration abolished by electric shock", JAMA, 1947. "Peter Agre - Autobiography". Nobelprize. ...

https://en.wikipedia.org/wiki/University_Hospitals_Cleveland_Medical_Center

... is to prevent cardiac death in patients who are at risk for sustained ventricular tachycardia or ventricular fibrillation. This ... and prophylactic therapy for patients at risk for sudden cardiac death due to ventricular fibrillation and ventricular ... refers to survivors of cardiac arrest secondary to ventricular fibrillation or hemodynamically unstable sustained ventricular ... In 2002 the MADITII trial showed benefit of ICD treatment in patients after myocardial infarction with reduced left ventricular ...

https://en.wikipedia.org/wiki/Implantable_cardioverter-defibrillator

They noted that a brief AC current of 20 amperes was able to jolt a heart from ventricular fibrillation back into a normal ... They noticed that when low-voltage shocks were applied to the heart, ventricular fibrillation was induced. Kouwenhoven also ... While undressing for his examination, the patient collapsed when his heart went into ventricular fibrillation. The resident at ... The dog's heart originally went through ventricular fibrillation, which occurs when the heart goes through rapid, electric ...

https://en.wikipedia.org/wiki/William_B._Kouwenhoven

If chronic this can result in arhythmias such as tachycardia, bradycardia, or ventricular fibrillation. An artificial pacemaker ...

https://en.wikipedia.org/wiki/Cardiac_pacemaker

These are typically a form of ventricular tachycardia known as Torsades de pointes which can cause faints, seizures, or even ... Less dangerous arrhythmias such as atrial fibrillation also occur, causing symptoms of heart racing or palpitations. However, ... Task Force for the Management of Patients with Ventricular Arrhythmias the Prevention of Sudden Cardiac Death of the European ... The Task Force for the Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death of the ...

https://en.wikipedia.org/wiki/Romano–Ward_syndrome

... often leading to ventricular fibrillation.[citation needed] This is a type of tachycardia that originates from above the ... Atrial fibrillation is one of the most common cardiac arrhythmias. In general, it is an irregular, narrow complex rhythm. ... "Atrial Fibrillation". The Lecturio Medical Concept Library. 11 August 2020. Retrieved 3 July 2021. Elsevier, Dorland's ... Depending on the patient's health and other variables such as medications taken for rate control, atrial fibrillation may cause ...

https://en.wikipedia.org/wiki/Tachycardia

The atrial and ventricular muscle tissue do not have this capability. Originally, it was believed that the atria had different ... Upon physical examination, it can be found by having an irregularly irregular rhythm, similar to how atrial fibrillation is ...

https://en.wikipedia.org/wiki/Wandering_atrial_pacemaker

The re-entry phenomenon may cause rapid heart rates (ventricular tachycardia and even ventricular fibrillation), and ischemia ... However, these cells are directly involved in the weakening of the tissue, leading to complications such as a ventricular free ... Collagen is not as strong or compliant as the myocardium that it replaced, this instability could lead to a ventricular ... The weakness may also lead to ventricular aneurysm, a localized dilation or ballooning of the heart chamber.[citation needed] ...

https://en.wikipedia.org/wiki/Myocardial_infarction_complications

Akathisia/psychomotor restlessness Urinary incontinence Anaphylaxis QT prolongation Ventricular fibrillation Ventricular ...

https://en.wikipedia.org/wiki/List_of_adverse_effects_of_venlafaxine

Using transthoracic echocardiograms, 3-D TEE and ECG traces, it is also possible to find left ventricular hypertrophy, bundle ... Some research has shown increased incidences[spelling?] of atrial fibrillation to be associated but this relationship is not ...

https://en.wikipedia.org/wiki/Quadricuspid_aortic_valve

... is a life-threatening cardiac arrhythmia in which the coordinated contraction of the ventricular myocardium is replaced by high ... encoded search term (Ventricular Fibrillation) and Ventricular Fibrillation What to Read Next on Medscape ... Ventricular fibrillation appeared during rapid atrial fibrillation in a patient with Wolff-Parkinson-White syndrome. View Media ... Ventricular fibrillation (VF) is a life-threatening cardiac arrhythmia in which the coordinated contraction of the ventricular ...

https://www.medscape.com/answers/158712-105840/what-is-the-role-of-wolff-parkinson-white-wpw-syndrome-in-the-etiology-of-ventricular-fibrillation-vf

Ventricular fibrillation (VF) is a severely abnormal heart rhythm (arrhythmia) that is life threatening. ... Ventricular fibrillation (VF) is a severely abnormal heart rhythm (arrhythmia) that is life threatening. ... VF; Fibrillation - ventricular; Arrhythmia - VF; Abnormal heart rhythm - VF; Cardiac arrest - VF; Defibrillator - VF; ... Fibrillation is an uncontrolled twitching or quivering of muscle fibers (fibrils). When it occurs in the lower chambers of the ...

https://medlineplus.gov/ency/article/007200.htm

... such as ventricular tachycardia (VT). The period of arrhythmia may not be extensive, but ventricular fibrillation that occurs ... ventricular fibrillation is usually a degeneration of other malignant arrhythmias, ... Ventricular fibrillation (VF) is rare in the pediatric population; when it does occur, ... without a few initial beats of ventricular tachy... ... In adults, ventricular fibrillation is preceded by ventricular ...

https://emedicine.medscape.com/article/892748-overview

"An Unusual Cause of Atrial Fibrillation With Rapid Ventricular Response" Chest Vol. 150 Iss. 4 (2016) Available at: http:// ...

https://works.bepress.com/igor-aksenov/3/

https://heart.bmj.com/content/87/4/379.altmetrics

... which is therefore classified as idiopathic ventricular fibrillation (IVF). A distinct group of IVF patients has been found to ... Ventricular fibrillation causes more than 300, 000 sudden deaths each year in the USA alone,. In approximately 5-12% of these ... Ventricular fibrillation causes more than 300, 000 sudden deaths each year in the USA alone,. In approximately 5-12% of these ... which is therefore classified as idiopathic ventricular fibrillation (IVF). A distinct group of IVF patients has been found to ...

https://ui.adsabs.harvard.edu/abs/1998Natur.392..293C

Posts Tagged ventricular fibrillation. RSS. March 2nd, 2015. Selections from Richard Lehmans Literature Review: March 2nd. ... ventricular fibrillation. April 9th, 2013. Quinidine Unavailable in Most of the World. Larry Husten, PHD Quinidine - the only ... idiopathic ventricular fibrillation (VF), and early repolarization syndrome - is no longer available in much of the world. In a ... ACS AF AHA anticoagulation aortic valve replacement apixaban aspirin atrial fibrillation CABG cardiovascular risk cholesterol ...

https://blogs.jwatch.org/cardioexchange/tag/ventricular-fibrillation/

You need to be signed in to access email alerts. If you have an account log in with your user name and password. If you dont have an account you can just enter your email address in the email box below ...

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... on vital organ perfusion in an animal model of ventricular fibrillation (VF) (Terlipressin in Cardiac Arrest (TERCA) study). ... terlipressin effect on vital organ perfusion during advanced life support in a porcine model of ventricular fibrillation. *A ... terlipressin effect on vital organ perfusion during advanced life support in a porcine model of ventricular fibrillation. Crit ... terlipressin effect on vital organ perfusion during advanced life support in a porcine model of ventricular fibrillation ...

https://ccforum.biomedcentral.com/articles/10.1186/cc7348

Phase Entrainment of Induced Ventricular Fibrillation: A Human Feasibility and Proof of Concept Study. / Holden, Arun V.; Begg ... Phase Entrainment of Induced Ventricular Fibrillation: A Human Feasibility and Proof of Concept Study. Journal of Atrial ... The high frequency pacing did not entrain the ventricular fibrillation, but altered the dominant frequency in all 8 patients, ... Holden, AV, Begg, GA, Bounford, K, Stegemann, B & Tayebjee, MH 2019, Phase Entrainment of Induced Ventricular Fibrillation: A ...

https://research.aston.ac.uk/en/publications/phase-entrainment-of-induced-ventricular-fibrillation-a-human-fea

Adult witnessed ventricular fibrillation OHCA of presumed cardiac cause were randomised 1:1 to either: (1) treatment: ... 2017) A randomised tRial of expedited transfer to a cardiac arrest centre for non-ST elevation ventricular fibrillation out-of- ... A randomised tRial of expedited transfer to a cardiac arrest centre for non-ST elevation ventricular fibrillation out-of- ... Cardiac arrest, Cardiac arrest--Treatment , Cardiac resuscitation, Ventricular fibrillation. Journal or Publication Title:. ...

http://wrap.warwick.ac.uk/87721/

Background: Atrial fibrillation with rapid ventricular response (AFib with RVR) is frequently associated with worse outcomes in ... 988-P: Diabetic Patients with Chronic Kidney Disease Who Are Hospitalized with Atrial Fibrillation with Rapid Ventricular ... Diabetic Patients with Chronic Kidney Disease Who Are Hospitalized with Atrial Fibrillation with Rapid Ventricular Response Are ...

https://diabetesjournals.org/diabetes/article-split/70/Supplement_1/988-P/140543/988-P-Diabetic-Patients-with-Chronic-Kidney

Regional and Temporal Variation of Ventricular and Conduction Tissue Activity During Ventricular Fibrillation in Canines. In: ... Regional and Temporal Variation of Ventricular and Conduction Tissue Activity During Ventricular Fibrillation in Canines. / Tan ... Regional and Temporal Variation of Ventricular and Conduction Tissue Activity During Ventricular Fibrillation in Canines. ... Regional and Temporal Variation of Ventricular and Conduction Tissue Activity During Ventricular Fibrillation in Canines. ...

https://mayoclinic.pure.elsevier.com/en/publications/regional-and-temporal-variation-of-ventricular-and-conduction-tis

Ventricular fibrillation complicating acute myocardial infarction in women. Session: Coronary artery disease - Epidemiology, ...

https://esc365.escardio.org/presentation/250678?resource=abstract

... Grant ...

http://scholars.uab.edu/display/grant-000339139

... is a life-threatening cardiac arrhythmia in which the coordinated contraction of the ventricular myocardium is replaced by high ... encoded search term (Ventricular Fibrillation) and Ventricular Fibrillation What to Read Next on Medscape ... Ventricular fibrillation appeared during rapid atrial fibrillation in a patient with Wolff-Parkinson-White syndrome. ... This image reveals ventricular fibrillation in a patient with a left ventricular assist device (LVAD). ...

https://www.staging.medscape.com/answers/158712-106320/what-are-the-differential-diagnoses-for-ventricular-fibrillation

The Effect of Antiarrhythmic Drugs on the Ventricular Fibrillation Waveform. EJF CARLISLE, JD ALLEN, George Kernohan, J ... Dive into the research topics of The Effect of Antiarrhythmic Drugs on the Ventricular Fibrillation Waveform. Together they ...

https://pure.ulster.ac.uk/en/publications/the-effect-of-antiarrhythmic-drugs-on-the-ventricular-fibrillatio-3/fingerprints/

... an effective and safe combination for refractory ventricular fibrillation. Simone Savastano, Enrico Baldi, Rita Camporotondo, ... an effective and safe combination for refractory ventricular fibrillation. / Savastano, Simone; Baldi, Enrico; Camporotondo, ... an effective and safe combination for refractory ventricular fibrillation. Europace : European pacing, arrhythmias, and cardiac ... an effective and safe combination for refractory ventricular fibrillation. In: Europace : European pacing, arrhythmias, and ...

https://moh-it.pure.elsevier.com/en/publications/percutaneous-stellate-ganglion-block-and-extracorporeal-cardiopul

Ventricular fibrillation (VF) begins as a quasiperiodic reentrant pattern of excitation in the ventricles with resulting poorly ... encoded search term (Ventricular Fibrillation in Emergency Medicine) and Ventricular Fibrillation in Emergency Medicine What to ... Ventricular Fibrillation in Emergency Medicine. Updated: Jan 12, 2021 * Author: Keith A Marill, MD, MS; Chief Editor: Erik D ... Handling of ventricular fibrillation in the emergency setting. Front Pharmacol. 2019. 10:1640. [QxMD MEDLINE Link]. [Full Text] ...

https://emedicine.staging.medscape.com/article/760832-overview

Management of ventricular fibrillation--a challenge. Indian Heart Journal. 1972 Oct; 24(4): 326-7. ...

https://imsear.searo.who.int/handle/123456789/5400

Reduced Absolute Myocardial Perfusion Relates to Left Ventricular Dysfunction in Lone Atrial Fibrillation Before and After ... Reduced Absolute Myocardial Perfusion Relates to Left Ventricular Dysfunction in Lone Atrial Fibrillation Before and After ...

https://www.well.ox.ac.uk/publications/907259

Ventricular Fibrillation Symptoms and Prevention ... Ventricular fibrillation may be fine or coarse; coarse ventricular ... Ventricular Fibrillation Signs and Symptoms , UCSF Health Learn more about ventricular tachycardia. VENTRICULAR FIBRILLATION ... Www.Symptoma.Com/En/Info/Ventricular-Fibrillation > ventricular < /a > Brief episodes of ventricular fibrillation is caused ... ventricular fibrillation (VF), premature ventricular contractions (PVC), and ventricular flutter. Fibrillation Signs and ...

https://www.infekcijukontrole.lt/2i6ao/ventricular-fibrillation-signs-and-symptoms.html

Shock‑on‑T : A ventricular arrhythmia (most often VF) is unduced by the delivery of a low energy shock during the ventricular ... by programmed ventricular stimulation, i.e. a train of nominally 8 ventricular stimuli at a fixed rate (nominally at a 600-ms ... In practice, a ventricular stimulation sequence (nominally 8 stimuli), at a fixed rate (nominally 150 bpm or a cycle length of ... during the ventricular vulnerable period (at a nominal coupling interval of 310 ms). ...

https://www.cardiocases.com/en/pacingdefibrillation/specificities/icd-implantation/boston-scientific/boston-ventricular

p class=p1,Refractory ventricular fibrillation (VF) is very difficult to manage. Up until recently, emergency providers were ... Esmolol in Refractory Ventricular Fibrillation Refractory Ventricular Fibrillation Treated with Esmolol Resuscitation, 2016 ... Refractory ventricular fibrillation (VF) is very difficult to manage. Up until recently, emergency providers were limited to ... Use of Double Sequential External Defibrillation for Refractory Ventricular Fibrillation During Out-of-Hospital Cardiac Arrest. ...

https://coreem.net/journal-reviews/esmolol-in-rvf/

2 comorbidity indices in a study evaluating patients with out-of-hospital episodes of ventricular fibrillation. ... Chronic and Symptom Factors , Ventricular Fibrillation. Purpose: To evaluate a patient for comorbidities using the chronic and ... et al developed 2 comorbidity indices in a study evaluating patients with out-of-hospital episodes of ventricular fibrillation ...

https://www.medicalalgorithms.com/ventricular-fibrillation-symptoms

... is a life-threatening cardiac arrhythmia in which the coordinated contraction of the ventricular myocardium is replaced by high ... encoded search term (Ventricular Fibrillation) and Ventricular Fibrillation What to Read Next on Medscape ... Ventricular fibrillation appeared during rapid atrial fibrillation in a patient with Wolff-Parkinson-White syndrome. ... This image reveals ventricular fibrillation in a patient with a left ventricular assist device (LVAD). ...

https://emedicine.staging.medscape.com/article/158712-workup

Adams-Stokes Attacks caused by Ventricular Fibrillation. In a Man with otherwise normal Heart - Storstein, Ole ... Adams-Stokes Attacks caused by Ventricular Fibrillation. In a Man with otherwise normal Heart. ... VF initiated by shortcoupled premature ventricular complexes (ScPVCs) [12]. [13]. [14]. [15]. [16]. or based on the presence of ...

https://scite.ai/reports/adams-stokes-attacks-caused-by-ventricular-XMpLJ9

Ventricular fibrillation (VF) is a common cause of sudden cardiac death (SCD) and is unfortunately without a cure. Current ... Catheter Ablation of Ventricular Fibrillation. Ezzeddine, Fatima M; Darlington, Ashley M; DeSimone, Christopher V; Asirvatham, ... Fibrilación Ventricular / Ablación por Catéter Límite: Humanos Idioma: Inglés Revista: Card Electrophysiol Clin Año: 2022 Tipo ... Fibrilación Ventricular / Ablación por Catéter Límite: Humanos Idioma: Inglés Revista: Card Electrophysiol Clin Año: 2022 Tipo ...

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[ 4 ] Ventricular tachycardia (VT) may degenerate into VF. (medscape.com)
when it does occur, ventricular fibrillation is usually a degeneration of other malignant arrhythmias, such as ventricular tachycardia (VT). (medscape.com)
The period of arrhythmia may not be extensive, but ventricular fibrillation that occurs without a few initial beats of ventricular tachycardia is unusual. (medscape.com)
In adults, ventricular fibrillation is preceded by ventricular tachycardia in approximately 80% of cases. (medscape.com)
In a population of patients with known ventricular arrhythmias, individuals who had ventricular fibrillation were more likely to have underlying significant heart disease (eg, cardiac tumors, long QT syndrome, structural congenital heart disease) than patients with ventricular tachycardia. (medscape.com)
These precipitating factors include electrolyte abnormalities, proarrhythmic medications, alterations in the sympathetic-parasympathetic balance (particularly increased catecholamines), hypothermia or hyperthermia, primary electrical disease (eg, long QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia), and hypoxia/ischemia. (medscape.com)
The triggers for ventricular tachycardia are diverse. (medscape.com)
For more information, see Ventricular Tachycardia and Pediatric Hypertrophic Cardiomyopathy . (medscape.com)
Belhassen B, Viskin S. Idiopathic ventricular tachycardia and fibrillation. (medscape.com)
ventricular tachycardia (VT), ventricular fibrillation (VF), pulseless electrical activity (PEA), and asystole . (medscape.com)
Learn more about ventricular tachycardia. (infekcijukontrole.lt)
This includes a subset of arrhythmias such as ventricular tachycardia (VT), ventricular fibrillation (VF), premature ventricular contractions (PVC), and ventricular flutter. (infekcijukontrole.lt)
You may also have symptoms of ventricular tachycardia (VT). (infekcijukontrole.lt)
[ 73 ] In patients with dilated cardiomyopathy (DCM) (unlike those with ischemic cardiomyopathy), increased asymptomatic ventricular ectopy and nonsustained ventricular tachycardia (VT) are not predictive of VF. (medscape.com)
Use of beta-blockers for the treatment of cardiac arrest due to ventricular fibrillation/pulseless ventricular tachycardia: a systematic review. (emergencymedicinecases.com)
Use of the impella microaxial blood pump for ablation of hemodynamically unstable ventricular tachycardia. (cardiacrhythmnews.com)
The machine will not deliver a shock unless the heart is in ventricular fibrillation or ventricular tachycardia. (nursingcenter.com)
Ventricular tachycardia/fibrillation ablation : the state of the art based on the VeniceChart international consensus document / edited by Andrea Natale, Antonio Raviele . (upol.cz)
60 or atrioventricular block] or tachydysrhythmias [ventricular tachycardia/fibrillation or atrial tachycardia with 2:1 block]) (1-4). (cdc.gov)
Natural history indicates a somber diagnosis in symptomatic patients with a high index of arrhythmic SCD secondary to very fast polymorphic ventricular tachycardia bursts, which degenerate into VF. (southampton.ac.uk)
Until then, however, beta blockade is still indicated in NonSTEMI when the patient has hypertension and also if there is tachycardia (tachycardia that is not compensatory for low stroke volume, which may be due to poor LV function, valvular disease, low left ventricular end-diastolic volume, or low systemic vascular resistance). (blogspot.com)
This may result in QT prolongation and cardiac arrhythmias including ventricular tachycardia, ventricular fibrillation and Torsade de Pointes. (nafarma.com)
In controls reperfused with aerobic perfusion medium, 100% of hearts developed ventricular tachycardia 1.48±0.78 seconds after reperfusion, and ventricular fibrillation occurred 13.47±2.91 seconds after reperfusion. (bvsalud.org)
Also in hearts reperfused with anoxic perfusion medium, 100% of hearts developed ventricular tachycardia 1.98±0.96 seconds after reperfusion, and ventricular fibrillation occurred 27.01±18.52 seconds after reperfusion. (bvsalud.org)
In conclusion anoxic reperfusion delayed ventricular fibrillation but prevent neither ventricular fibrillation nor ventricular tachycardia. (bvsalud.org)
Digitalis drug is used in the treatment of Congestive cardiac failure, Left ventricular failure, Arterial fibrillation and flutter, premature beats and Supra-ventricular tachycardia. (medicoinfo.org)
Tenormin reduces the heart rate and is used for treatment of abnormally rapid heart rhythms, arterial hypertension, angina, acute myocardial infraction, tachycardia (different types), ventricular fibrillation and others. (canadianbopharmacy.com)
After several years and multiple medical regimens were unsuccessful in controlling frequent episodes of ventricular tachycardia, the patient had undergone several additional procedures aimed at reducing the incidence of arrhythmia. (thoracics.org)
I guess not having anymore bouts of afib helped, but last year I had to go to hospital twice for treatment for SVT, sinus ventricular tachycardia. (diabetesdaily.com)
n\nThe most important cardiac selleck inhibitor arrhythmias including ventricular tachycardia, sinus arrest, and sinus exit block. (ainhibitor.com)

2017 AHA/ACC/HRS Guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: a report of the American College of Cardiology/American Heart Association Task Force on clinical practice guidelines and the Heart Rhythm Society [published correction appears in J Am Coll Cardiol. (medlineplus.gov)
However, technologic advances in both implantable and external automated defibrillators have made these devices an important part in the management of malignant ventricular arrhythmias. (medscape.com)
Quinidine - the only drug known to be effective in preventing lethal ventricular arrhythmias in people with several rare conditions, including Brugada syndrome, idiopathic ventricular fibrillation (VF), and early repolarization syndrome - is no longer available in much of the world. (jwatch.org)
As a initial step towards developing methods that can terminate ventricular arrhythmias painlessly, we aim to determine if pacing stimuli at a rate of 5/s applied via an implantable cardiac defibrillator (ICD) can modify human ventricular fibrillation. (aston.ac.uk)
The relationships among ventricular arrhythmias, left ventricular dysfunction, and mortality in the 2 years after myocardial infarction. (medscape.com)
Bikkina M, Larson MG, Levy D. Prognostic implications of asymptomatic ventricular arrhythmias: the Framingham Heart Study. (medscape.com)
Arrhythmias originating from the ventricular myocardium or His-Purkinje system are grouped under ventricular arrhythmia (VA). While a few seconds may not result in problems, longer periods are dangerous. (infekcijukontrole.lt)
Fibrillation Signs and symptoms of an arrhythmia may include: Chest pain or discomfort Shortness of breath Palpitations Racing heart sensation Treatment for arrhythmias depend upon the cause. (infekcijukontrole.lt)
Percutaneously implantable temporary cardiac support devices 3 that can support the circulation during rapid ventricular arrhythmias and arrhythmia occurring in patients with already permanently implanted left ventricular assist devices may allow this possibility. (cardiacrhythmnews.com)
Fatal or life-threatening cardiomyopathy and ventricular arrhythmias were reported. (nih.gov)
a clinical case report from Bogota, Colombia - and the work of Dr. Kalyanam Shivkumar, MD, PhD, Director, UCLA Cardiac Arrhythmia Center on treating ventricular arrhythmias with cardiac sympathetic denervation, including an upcoming clinical trial. (thoracics.org)
At six months, post surgery, the patient has had no further cardiac events or ventricular arrhythmias reported or recorded by her device. (thoracics.org)
al) have published several papers about their experiences treating patients with persistant ventricular arrhythmias. (thoracics.org)
In their work, which is one of the largest studies to date, the authors report their experiences with both selective left-sided cardiac sympathetic denervation (LCSD) alone or bilateral cardiac sympathetic denervation (BCSD) as a last-ditch treatment for persistent ventricular arrhythmias. (thoracics.org)

Ventricular fibrillation (VF) is a life-threatening cardiac arrhythmia in which the coordinated contraction of the ventricular myocardium is replaced by high-frequency, disorganized excitation, resulting in [the effective] failure of the heart to pump blood. (medscape.com)
Ventricular fibrillation (VF) is a severely abnormal heart rhythm ( arrhythmia ) that is life threatening. (medlineplus.gov)
Various factors can lead to the lowering of the ventricular fibrillation threshold and, thus, increase the likelihood of an arrhythmia proceeding to ventricular fibrillation. (medscape.com)
Shock‑on‑T : A ventricular arrhythmia (most often VF) is unduced by the delivery of a low energy shock during the ventricular vulnerable period. (cardiocases.com)
induction by programmed electrical stimulation (PES): the aim is to induce an arrhythmia (most often VT) by programmed ventricular stimulation, i.e. a train of nominally 8 ventricular stimuli at a fixed rate (nominally at a 600-ms cycle length), followed by 1 to 4 premature stimuli. (cardiocases.com)
Atrial fibrillation is the most common sustained arrhythmia encountered in clinical practice. (elsevier.com)
However, magnesium deficiency can result in disturbances in nearly every organ system and can cause potentially fatal complications (eg, ventricular arrhythmia, coronary artery vasospasm, sudden death). (medscape.com)
Atrial fibrillation (AF) is the most common chronic arrhythmia associated with heart failure (HF) [ 1 - 4 ]. (sch.ac.kr)
LVADs can also be lifesaving by maintaining hemodynamics during ventricular arrhythmia. (elsevier.com)
As presented here, a continuous-flow LVAD successfully provided hemodynamic support to a patient in sustained ventricular fibrillation for over 12 hours when the internal defibrillator was unable to terminate the arrhythmia. (elsevier.com)
The FDA analyzed reports of patients who developed QT prolongation, torsades de pointes, and ventricular arrhythmia in association with the use of cisapride to assess probable etiology and risk factors. (nih.gov)

In approximately 5-12% of these cases, there are no demonstrable cardiac or non-cardiac causes to account for the episode, which is therefore classified as idiopathic ventricular fibrillation (IVF). (harvard.edu)
Idiopathic ventricular fibrillation in out-of-hospital cardiac arrest survivors. (medscape.com)
Idiopathic ventricular fibrillation. (bvsalud.org)
8. Sumiyoshi M, Nakata Y, Hisaoka T. A case of idiopathic ventricular fibrillation with incomplete right bundle branch block and persistent ST segment elevation Jpn Heart J 1993, 34: 661-666 9. (southampton.ac.uk)

Surface ECG demonstrates no identifiable QRS complexes, although a wide range of amplitude of electrical activity is present, from sine-wave ventricular flutter to fine ventricular fibrillation, which may be difficult to distinguish from asystole (see image below). (medscape.com)
This can occur during VT or in conditions, such as Wolff-Parkinson-White syndrome , when atrial fibrillation or flutter waves pass rapidly through a bypass tract to the ventricular musculature. (medscape.com)
A good way to tell the difference between atrial flutter and atrial fibrillation is that if you were asked to count the atrial rate it would be possible in atrial flutter because there are discernible flutter waves. (acls.net)
The prevalence of common CVD diagnoses (hypertension, coronary heart disease, atrial fibrillation and flutter, heart failure, ischemic stroke, and venous thromboembolism) was evaluated as a function of the patients' body height stratified by age and sex. (biomedcentral.com)
Quinidine, a hydantoin anticonvulsant is used alone or with phenobarbital or other anticonvulsants to treat tonic-clonic seizures, psycho-motor seizures, neuropathic pain syndromes including Diabetic neuropathy, atrial fibrillation and flutter, vent. (medicoinfo.org)
Comparative Risks of Ischemic Stroke in Atrial Flutter versus Atrial Fibrillation. (cornell.edu)

Refractory ventricular fibrillation (VF) is very difficult to manage. (coreem.net)
Why esmolol for refractory Ventricular Fibrillation? (emergencymedicinecases.com)
In refractory Ventricular Fibrillation there is a huge increase in sympathetic tone at least partially due to the epinephrine given, which results in increased myocardial oxygen demand, exacerbation of myocardial ischemia, and depression of the VF threshold. (emergencymedicinecases.com)
What is the evidence for esmolol for refractory Ventricular Fibrillation? (emergencymedicinecases.com)
The evidence for esmolol in refractory Ventricular Fibrillation isn't the greatest - no big RCTs to be certain. (emergencymedicinecases.com)
Use of esmolol after failure of standard cardiopulmonary resuscitation to treat patients with refractory ventricular fibrillation. (emergencymedicinecases.com)

First-degree relatives of patients who are diagnosed with DCM, hypertrophic cardiomyopathy (HCM), or arrhythmogenic right ventricular dysplasia (ARVD) should be screened. (medscape.com)
The vast majority of individuals who experience SCD are patients with coronary artery disease (CAD) or structural heart disease, such as hypertrophic cardiomyopathy , anomalous coronary artery origins, or arrhythmogenic right ventricular dysplasia . (medscape.com)

Ventricular fibrillation with polymorphic morphology and cycle lengths varying from 80-280 milliseconds. (medscape.com)

For related topics, see Ventricular Fibrillation in Emergency Medicine , Sudden Cardiac Death , Hypertrophic Cardiomyopathy , and Pediatric Ventricular Fibrillation . (medscape.com)

Catheter Ablation of Ventricular Fibrillation. (bvsalud.org)
Role of the posterior papillary muscle and purkinje potentials in the mechanism of ventricular fibrillation in open chest dogs and swine: Effects of catheter ablation. (cardiacrhythmnews.com)

For patient education information, see the Heart Health Center and Healthy Living Center , as well as Cardiopulmonary Resuscitation (CPR) and the National Library of Medicine's Ventricular Fibrillation . (medscape.com)

The outcome in patients with ventricular fibrillation is better than in patients with asystole or pulseless electrical activity (PEA), and outcome may be further improved by prompt recognition and treatment of ventricular fibrillation. (medscape.com)
Treatment of ventricular fibrillation in a patient with prior diagnosis of long qt syndrome: Importance of precise electrophysiologic diagnosis to successfully ablate the trigger. (cardiacrhythmnews.com)

Primary prevention of ventricular fibrillation is at the heart of the management of Brugada syndrome. (intechopen.com)
Individuals with Brugada syndrome are prone to develop malignant ventricular tachyarrhythmias, which may lead to syncope, cardiac arrest, or SCD. (medscape.com)

In 8 patients undergoing defibrillation testing of a new/exchanged intracardiac defibrillator, five seconds of pacing at five stimuli per second was applied during the 10-20 seconds of induced ventricular fibrillation before the defibrillation shock was automatically applied, and the cardiac electrograms recorded and analyzed. (aston.ac.uk)
Ventricular fibrillation scaling exponent can guide timing of defibrillation and other therapies. (medscape.com)
This episode of ventricular fibrillation (VF) occurred in the emergency department and was present for less than 30 seconds prior to defibrillation, hence the coarse morphology. (medscape.com)
coarse ventricular fibrillation is more likely to convert after defibrillation than fine v-fib. (infekcijukontrole.lt)

Severe left ventricular dysfunction, a variety of cardiomyopathies, and acquired or idiopathic long QT syndrome also increase the risk of fibrillation. (medscape.com)
AF with left ventricular (LV) diastolic dysfunction plays an important role in the prevalence and severity of HF, rather than AF with systolic dysfunction. (sch.ac.kr)
the electrocardiogram analysis identified 59% of ACS with sus ST and 41% of ACS without sus ST. Left ventricular dysfunction was observed in 36.46% of our patients. (bvsalud.org)
Sinus bradycardia and atrial fibrillation were detected more commonly in patients with history of urinary dysfunction. (ainhibitor.com)
The World Health Organization (WHO) has five classifications for pulmonary hypertension, and all except one of these groups can result in cor pulmonale (WHO Classification group 2 is pulmonary artery hypertension due to left ventricular [LV] dysfunction). (medscape.com)

In patients who have had an myocardial infarction (MI), the use of 2-D echocardiograms to evaluate left wall ̶ motion abnormalities (using the left ventricular [LV] wall ̶ motion score index) can help to predict outcome and the risk for major cardiac events, including sudden death. (medscape.com)
Although myocardial ischemia during asthma has been described in literature, acute myocardial infarction and ventricular fibrillation with normal coronary arteries in patients with asthma bronchiale is a rare entity. (gazi.edu.tr)

Is human ventricular fibrillation different from experimental models? (ox.ac.uk)

Important understanding of unique electroanatomic transition sites in the ventricular myocardium including the base of the papillary muscles and the perimitral valve region may help merge current mapping paradigms with the basic understanding of the electrophysiology behind the maintenance of ventricular fibrillation. (cardiacrhythmnews.com)
PACES/HRS expert consensus statement on the management of the asymptomatic young patient with a Wolff-Parkinson-White (WPW, ventricular preexcitation) electrocardiographic pattern: developed in partnership between the Pediatric and Congenital Electrophysiology Society (PACES) and the Heart Rhythm Society (HRS). (bmj.com)

Sudden coronary death: relation of amount and distribution of coronary narrowing at necropsy to previous symptoms of myocardial ischemia, left ventricular scarring and heart weight. (medscape.com)
Ventricular fibrillation can cause sudden cardiac arrest (SCA), which requires immediate medical attention. (infekcijukontrole.lt)
Ventricular fibrillation (VF) is a common cause of sudden cardiac death (SCD) and is unfortunately without a cure . (bvsalud.org)
Ventricular preexcitation in children and young adults: atrial myocarditis as a possible trigger of sudden death. (bmj.com)

The electrical activity in ventricular fibrillation is characterized by chaotic depolarization of cells throughout the ventricular myocardium. (medscape.com)
Ventricular fibrillation may be initiated when an area of myocardium has refractory and conducting portions, and, as in any reentrant circuit, this combination promotes a self-sustaining rhythm. (medscape.com)

Metoprolol treats premature ventricular contractions (PVCs), which are extra heartbeats that disrupt the regular heart rhythm, sometimes causing the sensation of "fluttering" or a skipped beat in the chest. (druggenius.com)

Coronary artery disease (CAD) is the single most common etiologic factor predisposing patients to ventricular fibrillation (VF). (medscape.com)
After initial resuscitation, therapy in patients with ventricular fibrillation is primarily focused on preventing the antecedent ventricular tachycardias. (medscape.com)
300 beats per minute [bpm]) presents a potential risk for degeneration to ventricular fibrillation in patients with Wolff-Parkinson-White (WPW) syndrome . (medscape.com)
The high frequency pacing did not entrain the ventricular fibrillation, but altered the dominant frequency in all 8 patients, and modulated the phase computed via the Hilbert Transform, in four of the patients. (aston.ac.uk)
Mechanisms of ventricular fibrillation initiation in MADIT II patients with implantable cardioverter defibrillators. (medscape.com)
Hallstrom et al developed 2 comorbidity indices in a study evaluating patients with out-of-hospital episodes of ventricular fibrillation. (medicalalgorithms.com)
So while we're waiting for some bigger multicentre RCTs, for now, consider esmolol after 3 shocks, 3mg of epi and 300mg of amiodarone in your refractory Ventrcular Fibrillation patients. (emergencymedicinecases.com)
This study assessed the clinical utility of mitral annulus velocity in the evaluation of left ventricular diastolic function in patients with atrial fibrillation. (elsevier.com)
Mitral inflow and mitral annulus velocities were measured simultaneously with tau in 27 patients with nonrheumatic atrial fibrillation at the cardiac catheterization laboratory. (elsevier.com)
Mitral annulus velocity is useful in the detection of impaired left ventricular relaxation and estimation of filling pressure even in patients with atrial fibrillation. (elsevier.com)
However, non-invasive echocardiographic estimation is complicated in patients with atrial fibrillation (AF). (sch.ac.kr)
Approximately half of patients with HF show preserved left ventricular ejection fraction (LVEF), and AF is more prevalent in patients with HF with preserved rather than reduced LVEF [ 5 - 9 ]. (sch.ac.kr)
Left ventricular assist device (LVAD) therapy improves survival and quality of life by mechanically unloading the left ventricle and maintaining hemodynamics in patients with end-stage heart failure. (elsevier.com)
In contrast, the prevalence of atrial fibrillation and venous thromboembolism was higher in taller patients. (biomedcentral.com)
Safety and Efficacy of Low-Dose Prasugrel as Part of Triple Therapy With Aspirin and Oral Anticoagulants in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention - From the TWMU-AF PCI Registry. (twmu.ac.jp)
Prevalence, clinical characteristics, and outcome of atrial functional mitral regurgitation in hospitalized heart failure patients with atrial fibrillation. (twmu.ac.jp)
Stroke Risk and Mortality in Patients With Ventricular Assist Devices. (cornell.edu)
Most patients eventually develop atrial fibrillation because of progressive dilation of the atria. (mhmedical.com)

In this paper, we propose a novel method for predicting acute clinical deterioration triggered by hypotension, ventricular fibrillation, and an undiagnosed multiple disease condition using biological signals, such as heart rate, RR interval, and blood pressure. (fujita-hu.ac.jp)

Ventricular fibrillation (VF) occurs in a variety of clinical situations but is most often associated with coronary artery disease (CAD). (medscape.com)
In age- and BMI-adjusted logistic regression analyses, an increased body height was negatively associated with coronary heart disease (OR = 0.91 in women and OR = 0.87 in men per 10-cm increase in height) and strongly positively associated with atrial fibrillation (OR = 1.25 in women and men) and venous thromboembolism (OR = 1.23 in women and OR = 1.24 in men). (biomedcentral.com)
Based on these findings, the potential of MR antagonists has been evaluated in other cardiovascular diseases, including coronary artery disease, arterial hypertension, heart failure with preserved ejection fraction, pulmonary hypertension, atrial fibrillation, and heart valve disease. (cardiovascularpharmacology.org)

Ventricular fibrillation Diastolic heart failure signs and symptoms can range from mild to severe, and may include: Awakening at night with shortness of breath. (infekcijukontrole.lt)
VENTRICULAR FIBRILLATION SIGNS AND SYMPTOMS Upon the beginning of an attack of VF, usually the patient just collapses or loses consciousness as the brain's blood supply is cut off immediately after the heart stops pumping blood. (infekcijukontrole.lt)
No heart … Ventricular fibrillation is an emergency condition and signs and symptoms may include: Chest pain Rapid heartbeat Loss of consciousness Dizziness Shortness of breath Nausea Signs & symptoms. (infekcijukontrole.lt)
Ventricular fibrillation or v-fib, is a life-threatening and a medical emergency heart rhythm disturbance. (infekcijukontrole.lt)
If you were to look into the chest of a patient in ventricular fibrillation the heart would look as if you had Jello placed in a bowl and then bumped the bowl. (acls.net)
I see on the cardiac monitor that the patient is in ventricular fibrillation, the heart rhythm that immediately precedes death. (cnn.com)
Ventricular fibrillation is the uneven pumping of the heart due to the uncoordinated, asynchronous contraction of the ven-tricular muscle fibers of the heart that leads quickly to death from lack of oxygen to the brain. (metafilter.com)
Ven-tricular fibrillation is terminated by the use of a defibrillator, which provides a pulse shock to the chest to restore the heart rhythm. (metafilter.com)
We can see mum's heart was in Ventricular Fibrillation (VF). (philips.com.sg)
Ventricular fibrillation without apparent heart disease: description of six cases. (southampton.ac.uk)
When left untreated, death can occur due to a lowered heart rate or rapid, irregular rhythm of the lower chambers of your heart (ventricular fibrillation). (yardandgarage.com)
Right-sided ventricular disease caused by a primary abnormality of the left side of the heart or congenital heart disease is not considered cor pulmonale, but cor pulmonale can develop secondary to a wide variety of cardiopulmonary disease processes. (medscape.com)
Simples congenital heart anomalies like atrial and ventricular septum defects, ductus arteriosus or pulmonary vein transposition lead to the formation of a left-to-right shunt. (bme.hu)

BNP is highly specific and sensitive for this diagnosis when elevated left ventricular (LV) end-diastolic pressure is causing increased myocardial oxygen consumption and decreased cardiac output, leading to the abnormal myocardial substrate conditions conducive to the development of VF. (medscape.com)
Radiographs can also show signs of left or right ventricular hypertrophy. (medscape.com)
The clinical usefulness of conventional Doppler indexes is limited in atrial fibrillation because of the altered left atrial pressure and loss of synchronized atrial contraction. (elsevier.com)
001). The E/E' ratio of ≥11 could predict elevated left ventricular filling pressure (≥15 mm Hg) with a sensitivity of 75% (9 of 12) and a specificity of 93% (14 of 15). (elsevier.com)
Continuous flow left ventricular assist devices (CF-LVADs) have been increasingly used as destination therapy (DT). (ismics.org)
Left ventricular (LV) filling pressure can be estimated using echocardiographic measurements, including the ratio of transmitral early peak flow velocity to tissue Doppler mitral annular motion velocity (E/e′) during sinus rhythm. (sch.ac.kr)
A bedside ultrasound was done that was of imperfect quality but showed good left ventricular function. (blogspot.com)
Recurrent takotsubo syndrome with worsening of left ventricular outflow obstruction during haemodialysis: a case report. (twmu.ac.jp)
Oedema is instituted or waste material may help reduce left ventricular myocytes. (manguerascartagenasas.com)
It is essential to demonstrate precisely, for the success of reconstructive surgical procedures, which are at many times multi-step interventions, how the ventricular myocardial volume and functionality are, including the individual (split) functional parameters of the left and right ventricle. (bme.hu)
In the past decade, a series of experimental studies using models with cell type-specific MRs uncovered the cellular and molecular mechanisms underlying its detrimental effect on left ventricular remodeling. (cardiovascularpharmacology.org)

Atrial fibrillation may cause the following symptoms: Chest pressure or pain. (infekcijukontrole.lt)
Other symptoms you may experience if you have atrial fibrillation include: tiredness and being less able to exercise. (infekcijukontrole.lt)
Before a ventricular fibrillation episode, you may have signs and symptoms of an abnormally fast or … Atrial Fibrillation (AFib) Symptoms and Signs. (infekcijukontrole.lt)

Background: Atrial fibrillation with rapid ventricular response (AFib with RVR) is frequently associated with worse outcomes in diabetes mellitus (DM) and chronic kidney disease (CKD). (diabetesjournals.org)
Medical providers sometimes prescribe metoprolol to treat atrial fibrillation, also known as AFib or AF. (druggenius.com)

After 2 months she was readmitted with cardiac arrest due to recurrent ventricular fibrillation and intracardiac defibrillator implantation was performed. (gazi.edu.tr)

is being evaluated for new onset atrial fibrillation with rapid ventricular response. (medicowesome.com)
Cancer antigen-125 plasma level as a biomarker of new-onset atrial fibrillation in postmenopausal women. (twmu.ac.jp)
Secondary end points included the single components of the primary end point, new-onset or recurrence of atrial fibrillation, hospitalizations for symptomatic fluid overload, thrombosis or stenosis of the arteriovenous fistula, and changes in cardiac mass index. (elsevier.com)

As the treatments for asystole and ventricular fibrillation are different, it is important to differentiate between the two. (infekcijukontrole.lt)

arrest, respiratory arrest, or ventricular fibrillation without showing the etiology. (cdc.gov)
Harmful effects of exposures to electric shock would include respiratory arrest, ventricular fibrillation, and burns. (cdc.gov)

As vasopressin has never been available in Europe, we evaluated the effect of its synthetic analogue, terlipressin (TER), on vital organ perfusion in an animal model of ventricular fibrillation (VF) (Terlipressin in Cardiac Arrest (TERCA) study). (biomedcentral.com)

Atrial fibrillation is an irregular and uncoordinated contraction of the cardiac muscle of atria.It can be a chronic condition, usually treated with anticoagulation and sometimes with conversion to normal sinus rhythm.In this condition the normal electrical pulses … The 2 bottom chambers are the ventricles. (infekcijukontrole.lt)

Thus, ventricular fibrillation as a terminal rhythm in cardiac arrest may result from various causes. (medscape.com)
Introduction: Shock-resistant ventricular fibrillation (VF) poses a therapeutic challenge during out-of-hospital cardiac arrest (OHCA). (utwente.nl)

2016 ESC guidelines for the management of atrial fibrillation developed in collaboration with EACTS. (bmj.com)

While modern devices have been associated with decreased stroke risk, postoperative atrial fibrillation (POAF) remains a common complication following cardiac surgery and is associated with numerous complications. (ismics.org)

Primary ventricular fibrillation is uncommon in children. (medscape.com)
4 , 5 Thus, brief mapping and targeting signals that may represent primary rotors at sites like the base of the papillary muscle may address the ventricular fibrillation itself (rather than the triggering beat alone). (cardiacrhythmnews.com)

In a study of pediatric out-of-hospital arrests, ventricular fibrillation was the initial recorded rhythm in 19% of cardiac arrests. (medscape.com)
Because ventricular fibrillation is usually a degeneration of ventricular tachycardias, the role ventricular tachycardias play in the evolution of the rhythm disturbance must be considered. (medscape.com)
Ventricular fibrillation is shown in the rhythm strip below. (medscape.com)
Ventricular fibrillation was generally viewed as a non-ablatable rhythm disturbance. (cardiacrhythmnews.com)
Any rhythm that is grossly irregular and you cannot find P waves an accurate guess would be atrial fibrillation. (acls.net)

Adult witnessed ventricular fibrillation OHCA of presumed cardiac cause were randomised 1:1 to either: (1) treatment: comprising expedited transfer to a CAC for goal-directed therapy including access to immediate reperfusion, or (2) control: comprising current standard of care involving delivery to the geographically closest hospital. (warwick.ac.uk)

Anatomy19

Organisms5

Diseases55

Chemicals and Drugs35

Analytical, Diagnostic and Therapeutic Techniques and Equipment62

Psychiatry and Psychology1

Phenomena and Processes18

Disciplines and Occupations3

Technology, Industry, Agriculture2

Information Science6

Named Groups1

Health Care25

Site of myocardial infarction. A determinant of the cardiovascular changes induced in the cat by coronary occlusion. (1/1728)

Mechanism linking T-wave alternans to the genesis of cardiac fibrillation. (2/1728)

Electrocardiographic measures of ventricular repolarisation dispersion in patients with coronary artery disease susceptible to ventricular fibrillation. (3/1728)

Differential effects of defibrillation on systemic and cardiac sympathetic activity. (4/1728)

Mechanisms of isoflurane-induced myocardial preconditioning in rabbits. (5/1728)

Percutaneous transluminal coronary angioplasty, alone or in combination with urokinase therapy, during acute myocardial infarction. (6/1728)

Atrial fibrillation detection and R-wave synchronization by Metrix implantable atrial defibrillator: implications for long-term efficacy and safety. The Metrix Investigators. (7/1728)

Intracoronary flecainide induces ST alternans and reentrant arrhythmia on intact canine heart: A role of 4-aminopyridine-sensitive current. (8/1728)

Ventricular Fibrillation

Atrial Fibrillation

Electric Countershock

Heart Arrest

Electrocardiography

Anti-Arrhythmia Agents

Cardiopulmonary Resuscitation

Arrhythmias, Cardiac

Tachycardia, Ventricular

Defibrillators

Heart Conduction System

Defibrillators, Implantable

Electrophysiologic Techniques, Cardiac

Cardiac Pacing, Artificial

Catheter Ablation

Amiodarone

Death, Sudden, Cardiac

Body Surface Potential Mapping

Brugada Syndrome

Cardiac Complexes, Premature

Heart Atria

Dogs

Resuscitation

Refractory Period, Electrophysiological

Tachycardia

Pulmonary Veins

Heart Massage

Time Factors

Pericardium

Heart Rate

Heart Ventricles

Procainamide

Endocardium

Swine

Heart

Treatment Outcome

Flecainide

Out-of-Hospital Cardiac Arrest

Myocardial Ischemia

Action Potentials

Death, Sudden

Atrial Flutter

Electrocardiography, Ambulatory

Warfarin

Follow-Up Studies

Models, Cardiovascular

Myocardial Infarction

Recurrence

Anticoagulants

Bundle-Branch Block

Lidocaine

Epicardial Mapping

Emergency Medical Services

Ventricular Premature Complexes

Sotalol

Voltage-Sensitive Dye Imaging

Prospective Studies

NAV1.5 Voltage-Gated Sodium Channel

Atrial Appendage

Syncope

Pacemaker, Artificial

Disopyramide

Hypothermia, Induced

Wolff-Parkinson-White Syndrome

Myocardial Reperfusion Injury

Electrophysiology

Propafenone

Risk Factors

Fourier Analysis

Electric Injuries

Myocardium

Perfusion

Disease Models, Animal

Syndrome

Signal Processing, Computer-Assisted

Hypokalemia

Purkinje Fibers

Commotio Cordis

Predictive Value of Tests

Cardiac Electrophysiology