Venous thrombosis. Medical search

The formation or presence of a blood clot (THROMBUS) within a vein.

Formation and development of a thrombus or blood clot in the blood vessel.

Inflammation of a vein associated with a blood clot (THROMBUS).

Formation or presence of a blood clot (THROMBUS) in a blood vessel within the SKULL. Intracranial thrombosis can lead to thrombotic occlusions and BRAIN INFARCTION. The majority of the thrombotic occlusions are associated with ATHEROSCLEROSIS.

Formation or presence of a blood clot (THROMBUS) in the CRANIAL SINUSES, large endothelium-lined venous channels situated within the SKULL. Intracranial sinuses, also called cranial venous sinuses, include the superior sagittal, cavernous, lateral, petrous sinuses, and many others. Cranial sinus thrombosis can lead to severe HEADACHE; SEIZURE; and other neurological defects.

Radiographic visualization or recording of a vein after the injection of contrast medium.

A vein on either side of the body which is formed by the union of the external and internal iliac veins and passes upward to join with its fellow of the opposite side to form the inferior vena cava.

Veins draining the cerebrum.

The vein accompanying the femoral artery in the same sheath; it is a continuation of the popliteal vein and becomes the external iliac vein.

Agents that prevent clotting.

Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS.

A disorder of HEMOSTASIS in which there is a tendency for the occurrence of THROMBOSIS.

Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thrombin in blood coagulation. Factor V accomplishes this by forming a complex with factor Xa, phospholipid, and calcium (prothrombinase complex). Deficiency of factor V leads to Owren's disease.

Coagulation of blood in any of the CORONARY VESSELS. The presence of a blood clot (THROMBUS) often leads to MYOCARDIAL INFARCTION.

The vein formed by the union of the anterior and posterior tibial veins; it courses through the popliteal space and becomes the femoral vein.

Embolism or thrombosis involving blood vessels which supply intracranial structures. Emboli may originate from extracranial or intracranial sources. Thrombosis may occur in arterial or venous structures.

Veins which return blood from the intestines; the inferior mesenteric vein empties into the splenic vein, the superior mesenteric vein joins the splenic vein to form the portal vein.

Heparin fractions with a molecular weight usually between 4000 and 6000 kD. These low-molecular-weight fractions are effective antithrombotic agents. Their administration reduces the risk of hemorrhage, they have a longer half-life, and their platelet interactions are reduced in comparison to unfractionated heparin. They also provide an effective prophylaxis against postoperative major pulmonary embolism.

Blood clot formation in any part of the CAROTID ARTERIES. This may produce CAROTID STENOSIS or occlusion of the vessel, leading to TRANSIENT ISCHEMIC ATTACK; CEREBRAL INFARCTION; or AMAUROSIS FUGAX.

Formation or presence of a blood clot (THROMBUS) in the SUPERIOR SAGITTAL SINUS or the inferior sagittal sinus. Sagittal sinus thrombosis can result from infections, hematological disorders, CRANIOCEREBRAL TRAUMA; and NEUROSURGICAL PROCEDURES. Clinical features are primarily related to the increased intracranial pressure causing HEADACHE; NAUSEA; and VOMITING. Severe cases can evolve to SEIZURES or COMA.

An autosomal dominant disorder showing decreased levels of plasma protein S antigen or activity, associated with venous thrombosis and pulmonary embolism. PROTEIN S is a vitamin K-dependent plasma protein that inhibits blood clotting by serving as a cofactor for activated PROTEIN C (also a vitamin K-dependent protein), and the clinical manifestations of its deficiency are virtually identical to those of protein C deficiency. Treatment with heparin for acute thrombotic processes is usually followed by maintenance administration of coumarin drugs for the prevention of recurrent thrombosis. (From Harrison's Principles of Internal Medicine, 12th ed, p1511; Wintrobe's Clinical Hematology, 9th ed, p1523)

An absence or deficiency in PROTEIN C which leads to impaired regulation of blood coagulation. It is associated with an increased risk of severe or premature thrombosis. (Stedman's Med. Dict., 26th ed.)

A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa, factor V, phospholipid, and calcium ions. Deficiency of prothrombin leads to hypoprothrombinemia.

DEEP VEIN THROMBOSIS of an upper extremity vein (e.g., AXILLARY VEIN; SUBCLAVIAN VEIN; and JUGULAR VEINS). It is associated with mechanical factors (Upper Extremity Deep Vein Thrombosis, Primary) secondary to other anatomic factors (Upper Extremity Deep Vein Thrombosis, Secondary). Symptoms may include sudden onset of pain, warmth, redness, blueness, and swelling in the arm.

The venous trunk which receives blood from the lower extremities and from the pelvic and abdominal organs.

A condition characterized by a chronically swollen limb, often a leg with stasis dermatitis and ulcerations. This syndrome can appear soon after phlebitis or years later. Postphlebitic syndrome is the result of damaged or incompetent venous valves in the limbs. Distended, tortuous VARICOSE VEINS are usually present. Leg pain may occur after long period of standing.

Obstruction of the flow in the SPLANCHNIC CIRCULATION by ATHEROSCLEROSIS; EMBOLISM; THROMBOSIS; STENOSIS; TRAUMA; and compression or intrinsic pressure from adjacent tumors. Rare causes are drugs, intestinal parasites, and vascular immunoinflammatory diseases such as PERIARTERITIS NODOSA and THROMBOANGIITIS OBLITERANS. (From Juergens et al., Peripheral Vascular Diseases, 5th ed, pp295-6)

Obstruction of a blood vessel (embolism) by a blood clot (THROMBUS) in the blood stream.

A highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from six to twenty thousand. Heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Its function is unknown, but it is used to prevent blood clotting in vivo and vitro, in the form of many different salts.

Ultrasonography applying the Doppler effect combined with real-time imaging. The real-time image is created by rapid movement of the ultrasound beam. A powerful advantage of this technique is the ability to estimate the velocity of flow from the Doppler shift frequency.

A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance.

A condition caused by one or more episodes of DEEP VEIN THROMBOSIS, usually the blood clots are lodged in the legs. Clinical features include EDEMA; PAIN; aching; heaviness; and MUSCLE CRAMP in the leg. When severe leg swelling leads to skin breakdown, it is called venous STASIS ULCER.

Mechanical devices inserted in the inferior vena cava that prevent the migration of blood clots from deep venous thrombosis of the leg.

Surgical removal of an obstructing clot or foreign material from a blood vessel at the point of its formation. Removal of a clot arising from a distant site is called EMBOLECTOMY.

An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.

Fibrinolysin or agents that convert plasminogen to FIBRINOLYSIN.

Soluble protein fragments formed by the proteolytic action of plasmin on fibrin or fibrinogen. FDP and their complexes profoundly impair the hemostatic process and are a major cause of hemorrhage in intravascular coagulation and fibrinolysis.

Obstruction of a vein or VEINS (embolism) by a blood clot (THROMBUS) in the blood stream.

Veins in the neck which drain the brain, face, and neck into the brachiocephalic or subclavian veins.

The continuation of the axillary vein which follows the subclavian artery and then joins the internal jugular vein to form the brachiocephalic vein.

The presence of antibodies directed against phospholipids (ANTIBODIES, ANTIPHOSPHOLIPID). The condition is associated with a variety of diseases, notably systemic lupus erythematosus and other connective tissue diseases, thrombopenia, and arterial or venous thromboses. In pregnancy it can cause abortion. Of the phospholipids, the cardiolipins show markedly elevated levels of anticardiolipin antibodies (ANTIBODIES, ANTICARDIOLIPIN). Present also are high levels of lupus anticoagulant (LUPUS COAGULATION INHIBITOR).

The process of the interaction of BLOOD COAGULATION FACTORS that results in an insoluble FIBRIN clot.

Insertion of a catheter into a peripheral artery, vein, or airway for diagnostic or therapeutic purposes.

Tight coverings for the foot and leg that are worn to aid circulation in the legs, and prevent the formation of EDEMA and DEEP VEIN THROMBOSIS. PNEUMATIC COMPRESSION STOCKINGS serve a similar purpose especially for bedridden patients, and following surgery.

The venous trunk of the upper limb; a continuation of the basilar and brachial veins running from the lower border of the teres major muscle to the outer border of the first rib where it becomes the subclavian vein.

Formation or presence of a blood clot (THROMBUS) in the LATERAL SINUSES. This condition is often associated with ear infections (OTITIS MEDIA or MASTOIDITIS) without antibiotic treatment. In developed nations, lateral sinus thrombosis can result from CRANIOCEREBRAL TRAUMA; BRAIN NEOPLASMS; NEUROSURGICAL PROCEDURES; THROMBOPHILIA; and other conditions. Clinical features include HEADACHE; VERTIGO; and increased intracranial pressure.

A short thick vein formed by union of the superior mesenteric vein and the splenic vein.

A vitamin-K dependent zymogen present in the blood, which, upon activation by thrombin and thrombomodulin exerts anticoagulant properties by inactivating factors Va and VIIIa at the rate-limiting steps of thrombin formation.

The process which spontaneously arrests the flow of BLOOD from vessels carrying blood under pressure. It is accomplished by contraction of the vessels, adhesion and aggregation of formed blood elements (eg. ERYTHROCYTE AGGREGATION), and the process of BLOOD COAGULATION.

Use of infusions of FIBRINOLYTIC AGENTS to destroy or dissolve thrombi in blood vessels or bypass grafts.

An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.

Short thick veins which return blood from the kidneys to the vena cava.

Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.

The vessels carrying blood away from the capillary beds.

The vitamin K-dependent cofactor of activated PROTEIN C. Together with protein C, it inhibits the action of factors VIIIa and Va. A deficiency in protein S; (PROTEIN S DEFICIENCY); can lead to recurrent venous and arterial thrombosis.

Autoantibodies directed against phospholipids. These antibodies are characteristically found in patients with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; related autoimmune diseases, some non-autoimmune diseases, and also in healthy individuals.

An absence or reduced level of Antithrombin III leading to an increased risk for thrombosis.

The inferior part of the lower extremity between the KNEE and the ANKLE.

Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.

An antiphospholipid antibody found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic complications.

Material used for wrapping or binding any part of the body.

The natural enzymatic dissolution of FIBRIN.

A condition in which the hepatic venous outflow is obstructed anywhere from the small HEPATIC VEINS to the junction of the INFERIOR VENA CAVA and the RIGHT ATRIUM. Usually the blockage is extrahepatic and caused by blood clots (THROMBUS) or fibrous webs. Parenchymal FIBROSIS is uncommon.

Placement of an intravenous CATHETER in the subclavian, jugular, or other central vein.

Disorders or diseases associated with PUERPERIUM, the six-to-eight-week period immediately after PARTURITION in humans.

Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.

A coumarin that is used as an anticoagulant. Its actions and uses are similar to those of WARFARIN. (From Martindale, The Extra Pharmacopoeia, 30th ed, p233)

Large endothelium-lined venous channels situated between the two layers of DURA MATER, the endosteal and the meningeal layers. They are devoid of valves and are parts of the venous system of dura mater. Major cranial sinuses include a postero-superior group (such as superior sagittal, inferior sagittal, straight, transverse, and occipital) and an antero-inferior group (such as cavernous, petrosal, and basilar plexus).

Hemorrhagic and thrombotic disorders that occur as a consequence of inherited abnormalities in blood coagulation.

Recording changes in electrical impedance between electrodes placed on opposite sides of a part of the body, as a measure of volume changes in the path of the current. (Stedman, 25th ed)

Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.

The return of a sign, symptom, or disease after a remission.

Laboratory tests for evaluating the individual's clotting mechanism.

The time required for the appearance of FIBRIN strands following the mixing of PLASMA with phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides). It is a test of the intrinsic pathway (factors VIII, IX, XI, and XII) and the common pathway (fibrinogen, prothrombin, factors V and X) of BLOOD COAGULATION. It is used as a screening test and to monitor HEPARIN therapy.

Antiphospholipid antibodies found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. The antibodies are detected by solid-phase IMMUNOASSAY employing the purified phospholipid antigen CARDIOLIPIN.

Low-molecular-weight fragment of heparin, having a 4-enopyranosuronate sodium structure at the non-reducing end of the chain. It is prepared by depolymerization of the benzylic ester of porcine mucosal heparin. Therapeutically, it is used as an antithrombotic agent. (From Merck Index, 11th ed)

Elements of limited time intervals, contributing to particular results or situations.

Bleeding or escape of blood from a vessel.

Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.

Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.

Ultrasonography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image. This type of ultrasonography is well-suited to identifying the location of high-velocity flow (such as in a stenosis) or of mapping the extent of flow in a certain region.

Impaired venous blood flow or venous return (venous stasis), usually caused by inadequate venous valves. Venous insufficiency often occurs in the legs, and is associated with EDEMA and sometimes with VENOUS STASIS ULCERS at the ankle.

Tomography using x-ray transmission and a computer algorithm to reconstruct the image.

Hemorrhagic and thrombotic disorders that occur as a consequence of abnormalities in blood coagulation due to a variety of factors such as COAGULATION PROTEIN DISORDERS; BLOOD PLATELET DISORDERS; BLOOD PROTEIN DISORDERS or nutritional conditions.

A heparin fraction with a mean molecular weight of 4500 daltons. It is isolated from porcine mucosal heparin and used as an antithrombotic agent. (From Merck Index, 11th ed)

Duration of blood flow after skin puncture. This test is used as a measure of capillary and platelet function.

The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.

Endogenous factors and drugs that directly inhibit the action of THROMBIN, usually by blocking its enzymatic activity. They are distinguished from INDIRECT THROMBIN INHIBITORS, such as HEPARIN, which act by enhancing the inhibitory effects of antithrombins.

Formerly a constituent republic of Yugoslavia, comprising the Yugoslav section of the region of Macedonia. It was made a constituent republic in the 1946 constitution. It became independent on 8 February 1994 and was recognized as The Former Yugoslav Republic of Macedonia by the United States Board on Geographic Names 16 February 1994.

Rare chronic inflammatory disease involving the small blood vessels. It is of unknown etiology and characterized by mucocutaneous ulceration in the mouth and genital region and uveitis with hypopyon. The neuro-ocular form may cause blindness and death. SYNOVITIS; THROMBOPHLEBITIS; gastrointestinal ulcerations; RETINAL VASCULITIS; and OPTIC ATROPHY may occur as well.

The co-occurrence of pregnancy and a cardiovascular disease. The disease may precede or follow FERTILIZATION and it may or may not have a deleterious effect on the pregnant woman or FETUS.

Instruments that generate intermittent forces, uniformed or graduated, to facilitate the emptying of VEINS. These devices are used to reduce limb EDEMA and prevent venous THROMBOEMBOLISM, such as deep vein thrombosis in the legs.

Compounds, usually hormonal, taken orally in order to block ovulation and prevent the occurrence of pregnancy. The hormones are generally estrogen or progesterone or both.

Constituent composed of protein and phospholipid that is widely distributed in many tissues. It serves as a cofactor with factor VIIa to activate factor X in the extrinsic pathway of blood coagulation.

Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.

Flaps within the VEINS that allow the blood to flow only in one direction. They are usually in the medium size veins that carry blood to the heart against gravity.

Disease having a short and relatively severe course.

Catheters designed to be left within an organ or passage for an extended period of time.

Ultrasonography applying the Doppler effect, with frequency-shifted ultrasound reflections produced by moving targets (usually red blood cells) in the bloodstream along the ultrasound axis in direct proportion to the velocity of movement of the targets, to determine both direction and velocity of blood flow. (Stedman, 25th ed)

Oral contraceptives which owe their effectiveness to hormonal preparations.

Vein formed by the union (at the hilus of the spleen) of several small veins from the stomach, pancreas, spleen and mesentery.

Endogenous substances, usually proteins, that are involved in the blood coagulation process.

Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.

The attachment of PLATELETS to one another. This clumping together can be induced by a number of agents (e.g., THROMBIN; COLLAGEN) and is part of the mechanism leading to the formation of a THROMBUS.

The degree to which BLOOD VESSELS are not blocked or obstructed.

A 44-kDa highly glycosylated plasma protein that binds phospholipids including CARDIOLIPIN; APOLIPOPROTEIN E RECEPTOR; membrane phospholipids, and other anionic phospholipid-containing moieties. It plays a role in coagulation and apoptotic processes. Formerly known as apolipoprotein H, it is an autoantigen in patients with ANTIPHOSPHOLIPID ANTIBODIES.

The region of the lower limb in animals, extending from the gluteal region to the FOOT, and including the BUTTOCKS; HIP; and LEG.

The co-occurrence of pregnancy and a blood disease (HEMATOLOGIC DISEASES) which involves BLOOD CELLS or COAGULATION FACTORS. The hematologic disease may precede or follow FERTILIZATION and it may or may not have a deleterious effect on the pregnant woman or FETUS.

A protein derived from FIBRINOGEN in the presence of THROMBIN, which forms part of the blood clot.

Substances, usually endogenous, that act as inhibitors of blood coagulation. They may affect one or multiple enzymes throughout the process. As a group, they also inhibit enzymes involved in processes other than blood coagulation, such as those from the complement system, fibrinolytic enzyme system, blood cells, and bacteria.

Formation or presence of a blood clot (THROMBUS) in the CAVERNOUS SINUS of the brain. Infections of the paranasal sinuses and adjacent structures, CRANIOCEREBRAL TRAUMA, and THROMBOPHILIA are associated conditions. Clinical manifestations include dysfunction of cranial nerves III, IV, V, and VI, marked periorbital swelling, chemosis, fever, and visual loss. (From Adams et al., Principles of Neurology, 6th ed, p711)

Non-nucleated disk-shaped cells formed in the megakaryocyte and found in the blood of all mammals. They are mainly involved in blood coagulation.

A deficiency of blood coagulation factor V (known as proaccelerin or accelerator globulin or labile factor) leading to a rare hemorrhagic tendency known as Owren's disease or parahemophilia. It varies greatly in severity. Factor V deficiency is an autosomal recessive trait. (Dorland, 27th ed)

The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)

A flavoprotein amine oxidoreductase that catalyzes the reversible conversion of 5-methyltetrahydrofolate to 5,10-methylenetetrahydrofolate. This enzyme was formerly classified as EC 1.1.1.171.

Double-layered inflatable suits which, when inflated, exert pressure on the lower part of the wearer's body. The suits are used to improve or stabilize the circulatory state, i.e., to prevent hypotension, control hemorrhage, and regulate blood pressure. The suits are also used by pilots under positive acceleration.

A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases.

Enlarged and tortuous VEINS.

Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.

Extracellular vesicles generated by the shedding of CELL MEMBRANE blebs.

The visualization of deep structures of the body by recording the reflections or echoes of ultrasonic pulses directed into the tissues. Use of ultrasound for imaging or diagnostic purposes employs frequencies ranging from 1.6 to 10 megahertz.

A mutation caused by the substitution of one nucleotide for another. This results in the DNA molecule having a change in a single base pair.

A clinical syndrome characterized by repeated spontaneous hemorrhages and a remarkable increase in the number of circulating platelets.

A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.

Large veins on either side of the root of the neck formed by the junction of the internal jugular and subclavian veins. They drain blood from the head, neck, and upper extremities, and unite to form the superior vena cava.

The vein which drains the foot and leg.

Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.

A proteolytic enzyme that converts PLASMINOGEN to FIBRINOLYSIN where the preferential cleavage is between ARGININE and VALINE. It was isolated originally from human URINE, but is found in most tissues of most VERTEBRATES.

Formation of an infarct, which is NECROSIS in tissue due to local ISCHEMIA resulting from obstruction of BLOOD CIRCULATION, most commonly by a THROMBUS or EMBOLUS.

Radiography of the vascular system of the brain after injection of a contrast medium.

Burns produced by contact with electric current or from a sudden discharge of electricity.

Radiography of blood vessels after injection of a contrast medium.

Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.

Stents that are covered with materials that are embedded with chemicals that are gradually released into the surrounding milieu.

Blood-coagulation factor VIII. Antihemophilic factor that is part of the factor VIII/von Willebrand factor complex. Factor VIII is produced in the liver and acts in the intrinsic pathway of blood coagulation. It serves as a cofactor in factor X activation and this action is markedly enhanced by small amounts of thrombin.

A subnormal level of BLOOD PLATELETS.

Recording of change in the size of a part as modified by the circulation in it.

A spectrum of congenital, inherited, or acquired abnormalities in BLOOD VESSELS that can adversely affect the normal blood flow in ARTERIES or VEINS. Most are congenital defects such as abnormal communications between blood vessels (fistula), shunting of arterial blood directly into veins bypassing the CAPILLARIES (arteriovenous malformations), formation of large dilated blood blood-filled vessels (cavernous angioma), and swollen capillaries (capillary telangiectases). In rare cases, vascular malformations can result from trauma or diseases.

A cell surface glycoprotein of endothelial cells that binds thrombin and serves as a cofactor in the activation of protein C and its regulation of blood coagulation.

An individual having different alleles at one or more loci regarding a specific character.

Fixed drug combinations administered orally for contraceptive purposes.

The condition of an anatomical structure's being constricted beyond normal dimensions.

The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.

Cell adhesion molecule and CD antigen that mediates the adhesion of neutrophils and monocytes to activated platelets and endothelial cells.

Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.

A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and spleen). In time myelofibrosis occurs.

The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)

Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.

Condition in which the plasma levels of homocysteine and related metabolites are elevated (>13.9 µmol/l). Hyperhomocysteinemia can be familial or acquired. Development of the acquired hyperhomocysteinemia is mostly associated with vitamins B and/or folate deficiency (e.g., PERNICIOUS ANEMIA, vitamin malabsorption). Familial hyperhomocysteinemia often results in a more severe elevation of total homocysteine and excretion into the urine, resulting in HOMOCYSTINURIA. Hyperhomocysteinemia is a risk factor for cardiovascular and neurodegenerative diseases, osteoporotic fractures and complications during pregnancy.

A synthetic progestational agent with actions similar to those of PROGESTERONE. This racemic or (+-)-form has about half the potency of the levo form (LEVONORGESTREL). Norgestrel is used as a contraceptive, ovulation inhibitor, and for the control of menstrual disorders and endometriosis.

Enzymes catalyzing the dehydrogenation of secondary amines, introducing a C=N double bond as the primary reaction. In some cases this is later hydrolyzed.

A heterogeneous group of proteolytic enzymes that convert PLASMINOGEN to FIBRINOLYSIN. They are concentrated in the lysosomes of most cells and in the vascular endothelium, particularly in the vessels of the microcirculation.

The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.

Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.

A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.

A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.

A member of the serpin family of proteins. It inhibits both the tissue-type and urokinase-type plasminogen activators.

The venous trunk which returns blood from the head, neck, upper extremities and chest.

A series of progressive, overlapping events, triggered by exposure of the PLATELETS to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.

Operative procedures for the treatment of vascular disorders.

A condition marked by raised intracranial pressure and characterized clinically by HEADACHES; NAUSEA; PAPILLEDEMA, peripheral constriction of the visual fields, transient visual obscurations, and pulsatile TINNITUS. OBESITY is frequently associated with this condition, which primarily affects women between 20 and 44 years of age. Chronic PAPILLEDEMA may lead to optic nerve injury (see OPTIC NERVE DISEASES) and visual loss (see BLINDNESS).

A metallic element, atomic number 49, atomic weight 114.82, symbol In. It is named from its blue line in the spectrum. (From Dorland, 28th ed)

A thiol-containing amino acid formed by a demethylation of METHIONINE.

A medicated adhesive patch placed on the skin to deliver a specific dose of medication into the bloodstream.

An enzyme formed from PROTHROMBIN that converts FIBRINOGEN to FIBRIN.

Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.

Oral contraceptives which owe their effectiveness to synthetic preparations.

A compression of ILIAC VEIN that results in a decreased flow in the vein and in the left LOWER EXTREMITY due to a vascular malformation. It may result in left leg EDEMA, pain, iliofemoral DEEP VENOUS THROMBOSIS and POSTTHROMBOTIC SYNDROME. Compression of the left common ILIAC VEIN by the right common ILIAC ARTERY against the underlying fifth LUMBAR VERTEBRA is the typical underlying malformation.

A fibrin-stabilizing plasma enzyme (TRANSGLUTAMINASES) that is activated by THROMBIN and CALCIUM to form FACTOR XIIIA. It is important for stabilizing the formation of the fibrin polymer (clot) which culminates the coagulation cascade.

A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.

A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)

System established by the World Health Organization and the International Committee on Thrombosis and Hemostasis for monitoring and reporting blood coagulation tests. Under this system, results are standardized using the International Sensitivity Index for the particular test reagent/instrument combination used.

Hemorrhage following any surgical procedure. It may be immediate or delayed and is not restricted to the surgical wound.

Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

A spontaneous diminution or abatement of a disease over time, without formal treatment.

The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Procedure to accelerate the ability of a patient to walk or move about by reducing the time to AMBULATION. It is characterized by a shorter period of hospitalization or recumbency than is normally practiced.

Autosomal recessive inborn error of methionine metabolism usually caused by a deficiency of CYSTATHIONINE BETA-SYNTHASE and associated with elevations of homocysteine in plasma and urine. Clinical features include a tall slender habitus, SCOLIOSIS, arachnodactyly, MUSCLE WEAKNESS, genu varus, thin blond hair, malar flush, lens dislocations, an increased incidence of MENTAL RETARDATION, and a tendency to develop fibrosis of arteries, frequently complicated by CEREBROVASCULAR ACCIDENTS and MYOCARDIAL INFARCTION. (From Adams et al., Principles of Neurology, 6th ed, p979)

Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.

A weight-carrying structure for navigation of the air that is supported either by its own buoyancy or by the dynamic action of the air against its surfaces. (Webster, 1973)

Activated form of factor X that participates in both the intrinsic and extrinsic pathways of blood coagulation. It catalyzes the conversion of prothrombin to thrombin in conjunction with other cofactors.

A thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.

A condition characterized by the recurrence of HEMOGLOBINURIA caused by intravascular HEMOLYSIS. In cases occurring upon cold exposure (paroxysmal cold hemoglobinuria), usually after infections, there is a circulating antibody which is also a cold hemolysin. In cases occurring during or after sleep (paroxysmal nocturnal hemoglobinuria), the clonal hematopoietic stem cells exhibit a global deficiency of cell membrane proteins.

In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.

The space or compartment surrounded by the pelvic girdle (bony pelvis). It is subdivided into the greater pelvis and LESSER PELVIS. The pelvic girdle is formed by the PELVIC BONES and SACRUM.

The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome.

An individual in which both alleles at a given locus are identical.

Forceful administration under the skin of liquid medication, nutrient, or other fluid through a hollow needle piercing the skin.

Inorganic or organic compounds containing trivalent iron.

Hemorrhagic and thrombotic disorders resulting from abnormalities or deficiencies of coagulation proteins.

The giving of drugs, chemicals, or other substances by mouth.

A pharmaceutical preparation containing a mixture of esterified estrogens derived from estrogen sulfates, principally from ESTRONE sulfate. Esterified estrogen content should be 75-85% of the estrone sulfate and 6-15% of the EQUILIN sulfate.

Blockage of an artery due to passage of a clot (THROMBUS) from a systemic vein to a systemic artery without its passing through the lung which acts as a filter to remove blood clots from entering the arterial circulation. Paradoxical embolism occurs when there is a defect that allows a clot to cross directly from the right to the left side of the heart as in the cases of ATRIAL SEPTAL DEFECTS or open FORAMEN OVALE. Once in the arterial circulation, a clot can travel to the brain, block an artery, and cause a STROKE.

Removal of an implanted therapeutic or prosthetic device.

Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.

NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).

Obstruction of flow in biological or prosthetic vascular grafts.

A congenital disorder that is characterized by a triad of capillary malformations (HEMANGIOMA), venous malformations (ARTERIOVENOUS FISTULA), and soft tissue or bony hypertrophy of the limb. This syndrome is caused by mutations in the VG5Q gene which encodes a strong angiogenesis stimulator.

The use of ultrasound to guide minimally invasive surgical procedures such as needle ASPIRATION BIOPSY; DRAINAGE; etc. Its widest application is intravascular ultrasound imaging but it is useful also in urology and intra-abdominal conditions.

New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.

The inferior and superior venae cavae.

Inherited prothrombotic risk factors and cerebral venous thrombosis. (1/2331)

Fifteen patients with cerebral venous thrombosis were ascertained retrospectively. Their case notes were reviewed, and stored or new blood was assayed for factor V Leiden (FVL) mutation, prothrombin gene mutation 20201A, and 5,10 methylene tetrahydrofolate reductase (MTHFR) C677T mutation. A clinical risk factor was identified in 13 patients--the oral contraceptive pill (5), puerperium (1), HRT (1), mastoiditis (1), dehydration (1), lumbar puncture and myelography (1), carcinoma (1), lupus anticoagulant (2). In addition, two patients had the FVL mutation and five (one of whom also had the FVL mutation) were homozygous for the MTHFR mutation. The latter showed a higher than expected frequency compared to 300 healthy controls from South Wales (OR 3.15.95% Cl 1.01-9.83). No patient had the prothrombin 20201A mutation. Two patients died and three had a monocular visual deficit following anticoagulation (13) or thrombolytic (2) treatment, but there was no association between the presence of a primary prothrombotic risk factor and outcome. These results confirm the importance of investigating patients for both clinical predisposing factors and primary prothrombotic states. (+info)

Aetiologies and prognosis of Chinese patients with deep vein thrombosis of the lower extremities. (2/2331)

Deep vein thrombosis (DVT) of the lower extremities is not frequently encountered in Oriental patients. We investigated its aetiology and prognosis in 143 patients (65 males, 78 females), presenting to the National Taiwan University Hospital over 4.3 years, diagnosed by colour Doppler ultrasonography. Swelling and pain of the lower extremities were the most frequent presenting symptoms. The left femoropopliteal veins were more frequently involved than other parts of the lower extremities. In these patients, malignancy with or without intravenous catheterization was the most frequent cause (39 patients, 27%). Other common aetiologies included coagulopathy (29 patients, 20%), immobilization (24 patients, 17%) and catheter-related (13 patients, 9%). No definite aetiology could be determined in 37 patients (26%). During follow-up, 27 patients (19%) died, mostly with malignancy. Pulmonary embolism was noted in 16 patients and was not significantly directly related to death. Compared to similar studies in Caucasian patients, there were significant differences in the aetiology of DVT, with malignancy and coagulopathy more common in these Chinese patients. (+info)

Venous duplex scanning of the leg: range, variability and reproducibility. (3/2331)

Despite the many studies on venous haemodynamics using duplex, only a few evaluated the normal values, variability and reproducibility. Therefore, the range and variability of venous diameter, compressibility, flow and reflux were measured. To obtain normal values, 42 healthy individuals (42 limbs, 714 vein segments) with no history of venous disease were scanned by duplex. To determine the reproducibility the intra-observer variability was measured in 11 healthy individuals (187 vein segments) and the inter-observer variability in 15 healthy individuals (255 vein segments) and 13 patients (169 vein segments) previously diagnosed with deep venous thrombosis. Of the 714 normal vein segments, 708 (99%) were traceable, including the crural veins. Of the traceable vein segments, 675 (95%) were compressible and in 696 (98%) flow was present. Of the 42 common femoral vein segments, in 25 (60%) the reflux duration exceeded 1.0 s, but in the other proximal vein segments the reflux duration was less than 1.0 s (95% confidence interval 3.0-10.0). With the exception of the distal long saphenous vein, in the distal vein segments the reflux duration was less than 0.5 s (95% confidence interval 3.5-8.2). The coefficient of variation of the diameter measurements ranged from 14 to 50% and that of the reflux measurements from 28 to 60%. The kappa-coefficient of the inter-observer variability in the classification of compressibility measurements in the patients was 0. 77 and that of the reflux measurements was 0.86. This study shows that almost all veins were compressible in healthy individuals, except the distal femoral veins. In healthy individuals the duration of reflux of the proximal veins was less than 1.0 s and in the distal veins it was less than 0.5 s. The inter-observer variability of the reflux and compressibility measurements in the patients was good. (+info)

G20210A mutation in prothrombin gene and risk of myocardial infarction, stroke, and venous thrombosis in a large cohort of US men. (4/2331)

BACKGROUND: A single base pair mutation in the prothrombin gene has recently been identified that is associated with increased prothrombin levels. Whether this mutation increases the risks of arterial and venous thrombosis among healthy individuals is controversial. METHODS AND RESULTS: In a prospective cohort of 14 916 men, we determined the prevalence of the G20210A prothrombin gene variant in 833 men who subsequently developed myocardial infarction, stroke, or venous thrombosis (cases) and in 1774 age- and smoking status-matched men who remained free of thrombosis during a 10-year follow-up (control subjects). Gene sequencing was used to confirm mutation status in a subgroup of participants. Overall, carrier rates for the G20210A mutation were similar among case and control subjects; the relative risk of developing any thrombotic event in association with the 20210A allele was 1.05 (95% CI, 0.7 to 1.6; P=0.8). We observed no evidence of association between mutation and myocardial infarction (RR=0.8, P=0.4) or stroke (RR=1.1, P=0.8). For venous thrombosis, a modest nonsignificant increase in risk was observed (RR=1.7, P=0.08) that was smaller in magnitude than that associated with factor V Leiden (RR=3.0, P<0. 001). Nine individuals carried both the prothrombin mutation and factor V Leiden (5 controls and 4 cases). One individual, a control subject, was homozygous for the prothrombin mutation. CONCLUSIONS: In a large cohort of US men, the G20210A prothrombin gene variant was not associated with increased risk of myocardial infarction or stroke. For venous thrombosis, risk estimates associated with the G20210A mutation were smaller in magnitude than risk estimates associated with factor V Leiden. (+info)

Low-molecular-weight heparin in outpatient treatment of DVT. (5/2331)

Patients with a diagnosis of acute deep venous thrombosis have traditionally been hospitalized and treated with unfractionated heparin followed by oral anticoagulation therapy. Several clinical trials have shown that low-molecular-weight heparin is at least as safe and effective as unfractionated heparin in the treatment of uncomplicated deep venous thrombosis. The use of low-molecular-weight heparin in an outpatient program for the management of deep venous thrombosis provides a treatment alternative to hospitalization in selected patients. Use of low-molecular-weight heparin on an outpatient basis requires coordination of care, laboratory monitoring, and patient education and participation in treatment. Overlapping the initiation of warfarin permits long-term anticoagulation. Advantages include a decreased incidence of heparin-induced thrombocytopenia and fewer episodes of bleeding complications. Future clinical trials evaluating the safety and efficacy of low-molecular-weight heparin in the treatment of complicated deep venous thrombosis will further define appropriate indications for use and strategies for outpatient management. (+info)

Right atrial bypass grafting for central venous obstruction associated with dialysis access: another treatment option. (6/2331)

PURPOSE: Central venous obstruction is a common problem in patients with chronic renal failure who undergo maintenance hemodialysis. We studied the use of right atrial bypass grafting in nine cases of central venous obstruction associated with upper extremity venous hypertension. To better understand the options for managing this condition, we discuss the roles of surgery and percutaneous transluminal angioplasty with stent placement. METHODS: All patients had previously undergone placement of bilateral temporary subclavian vein dialysis catheters. Severe arm swelling, graft thrombosis, or graft malfunction developed because of central venous stenosis or obstruction in the absence of alternative access sites. A large-diameter (10 to 16 mm) externally reinforced polytetrafluoroethylene (GoreTex) graft was used to bypass the obstructed vein and was anastomosed to the right atrial appendage. This technique was used to bypass six lesions in the subclavian vein, two lesions at the innominate vein/superior vena caval junction, and one lesion in the distal axillary vein. RESULTS: All patients except one had significant resolution of symptoms without operative mortality. Bypass grafts remained patent, allowing the arteriovenous grafts to provide functional access for 1.5 to 52 months (mean, 15.4 months) after surgery. CONCLUSION: Because no mortality directly resulted from the procedure and the morbidity rate was acceptable, this bypass grafting technique was adequate in maintaining the dialysis access needed by these patients. Because of the magnitude of the procedure, we recommend it only for the occasional patient in whom all other access sites are exhausted and in whom percutaneous dilation and/or stenting has failed. (+info)

Evaluation of lidocaine as an analgesic when added to hypertonic saline for sclerotherapy. (7/2331)

PURPOSE: The efficacy of sclerosing agents for the treatment of telangiectasias and reticular veins is well established. The injection of these agents is often associated with pain, and it is not uncommon for sclerotherapists to include lidocaine with the sclerosants in an attempt to reduce the pain associated with treatment. However, there are concerns that this may reduce the overall efficacy of the treatment because of dilution of the sclerosant. Patient comfort and overall outcome associated with treatment using HS with lidocaine (LIDO) versus that using HS alone was compared. METHODS: Forty-two patients were prospectively entered into the study and randomized blindly to sclerotherapy with 23.4% HS or 19% LIDO. Study subjects and treating physicians were blinded to the injection solution used. Injection sites were chosen for veins ranging in size from 0.1 to 3 mm. Photographs of the area to be treated were taken, and the patients rated their pain. They were then observed at regular intervals for four months, and clinical data was collected. Thirty-five subjects completed the full follow-up period, and photographs of the injected area were taken again. Three investigators blinded to the treatment assignment then evaluated the photographs and scored the treatment efficacy according to a standardized system. RESULTS: In the HS group, 61.9% (13 of 21) patients rated their pain as none or mild, whereas 90.5% (19 of 21) of patients in the LIDO group had no or mild discomfort. This difference is significant, with a P value of.034. There was no difference in the overall efficacy of treatment between the two groups. The groups had similar rates of vein thrombosis and skin necrosis. CONCLUSION: Although lidocaine is often used with sclerosing agents, there are no previous reports in the literature to evaluate its effectiveness in reducing the pain experienced by the patient. In this study, patients receiving LIDO experienced significantly less discomfort at the time of injection than patients who received HS alone. There were no differences in the effectiveness of treatment or in the incidence of complications between the two groups. (+info)

Relief of obstructive pelvic venous symptoms with endoluminal stenting. (8/2331)

PURPOSE: To select patients for percutaneous transluminal stenting of chronic postthrombotic pelvic venous obstructions (CPPVO), we evaluated the clinical symptoms in a cohort of candidates and in a series of successfully treated patients. METHODS: The symptoms of 42 patients (39 women) with CPPVO (38 left iliac; average history, 18 years) were recorded, and the venous anatomy was studied by means of duplex scanning, subtraction venography, and computed tomography or magnetic resonance imaging. Successfully stented patients were controlled by means of duplex scanning and assessment of symptoms. RESULTS: The typical symptoms of CPPVO were reported spontaneously by 24% of patients and uncovered by means of a targeted interview in an additional 47%. Of 42 patients, 15 had venous claudication, four had neurogenic claudication (caused by dilated veins in the spinal canal that arise from the collateral circulation), and 11 had both symptoms. Twelve patients had no specific symptoms. Placement of a stent was found to be technically feasible in 25 patients (60%), was attempted in 14 patients, and was primarily successful in 12 patients. One stent occluded within the first week. All other stents were fully patent after a mean of 15 months (range, 1 to 43 months). Satisfaction was high in the patients who had the typical symptoms, but low in those who lacked them. CONCLUSION: Venous claudication and neurogenic claudication caused by venous collaterals in the spinal canal are typical clinical features of CPPVO. We recommend searching for these symptoms, because recanalization by means of stenting is often feasible and rewarding. (+info)

... cerebral venous sinus thrombosis, renal vein thrombosis, and ovarian vein thrombosis. Superficial venous thromboses cause ... Cerebral venous sinus thrombosis, cavernous sinus thrombosis and jugular vein thrombosis: thrombosis of the veins of the brain ... thrombosis of the hepatic vein) Thrombosis of the hepatic portal system, also known as splanchnic venous thrombosis: Thrombosis ... Venous thrombosis is blockage of a vein caused by a thrombus (blood clot). A common form of venous thrombosis is deep vein ...

https://en.wikipedia.org/wiki/Venous_thrombosis

... (CVST), cerebral venous and sinus thrombosis or cerebral venous thrombosis (CVT), is the ... In cerebral venous thrombosis, blood clots usually form both in the veins of the brain and the venous sinuses. The thrombosis ... Disorders that cause, or increase the risk for systemic venous thrombosis are associated with central venous thromboses. In ... Wikimedia Commons has media related to Cerebral venous sinus thrombosis. "Intracranial venous thrombosis - Patient UK". UCH ...

https://en.wikipedia.org/wiki/Cerebral_venous_sinus_thrombosis

Chronic venous thrombosis and venous insufficiency. In: Peripheral vascular sonography: a practical guide. Baltimore: Williams ... Haimovici, H. Ischemic forms of venous thrombosis: phlegmasia cerulea dolens, venous gangrene. Springfield, IlI: Charles C Tho ... Venous duplex imaging: should it replace hemodynamic tests for deep vein thrombosis? J Vasc Surg 1990; 11:53. Cronan, JJ. ... Diagnostic tests for venous thrombosis. In: Cranley JJ, ed. Vascular surgery. New York: Harper and Row, 1975. Christopoulos, D ...

https://en.wikipedia.org/wiki/Venous_translucence

It is defined by the occlusion of venous blood vessels by blood clots. There are two major types of VTE: deep-vein thrombosis ( ... Venous thromboembolism (VTE) is a common peripheral venous disease. ... "Venous thrombosis". Nature Reviews Disease Primers. 1 (1): 15006. doi:10.1038/nrdp.2015.6. PMID 27189130. S2CID 24689285. Furie ... On the contrary, venous clots are formed much slower, in terms of several days or even weeks. Abnormality of coagulation during ...

https://en.wikipedia.org/wiki/Blood_vessel_disorder

Ameri, A.; Bousser, M. G. (1992-02-01). "Cerebral Venous Thrombosis". Neurologic Clinics. 10 (1): 87-111. doi:10.1016/S0733- ... In 21.4% of cases, ischaemic strokes are caused by thrombosis. A thrombus is a blood clot which forms in a cerebral blood ... Stam, J. (2005-04-28). "Thrombosis of the Cerebral Veins and Sinuses". New England Journal of Medicine. 352 (17): 1791-1798. ... Enhanced platelet activation during MA has been observed which directly increases the risk of developing thrombosis. ...

https://en.wikipedia.org/wiki/Migrainous_infarction

Cerebral Venous Thrombosis". Stroke - Pathophysiology, Diagnosis, and Management (4th ed.). Churchill Livingstone. pp. 301-325 ... The cerebellar veins may be affected by infarction or thrombosis. They may be the draining site of abnormal fistulas. Diagram ... http://neuroangio.org/venous-brain-anatomy/veins-posterior-fossa/ Portal: Anatomy (CS1 maint: date and year, Articles with ...

https://en.wikipedia.org/wiki/Cerebellar_veins

López JA, Chen J (2009). "Pathophysiology of venous thrombosis". Thromb Res. 123 (Suppl 4): S30-4. doi:10.1016/S0049-3848(09) ...

https://en.wikipedia.org/wiki/Thrombogenicity

To date, arrhythmias, renal colic, venous thrombosis, and infections have been documented during space flights. The documented ... Auñón-Chancellor, Serena M.; Pattarini, James M.; Moll, Stephan; Sargsyan, Ashot (2020). "Venous Thrombosis during Spaceflight ...

https://en.wikipedia.org/wiki/Medical_treatment_during_spaceflight

... cerebral venous sinus thrombosis and thrombosis of the splanchnic veins. Cerebral venous sinus thrombosis may cause severe ... Capecchi M, Abbattista M, Martinelli I (October 2018). "Cerebral venous sinus thrombosis". Journal of Thrombosis and ... The Paul Ehrlich Institute has recorded 31 cerebral venous sinus thromboses (CVST) and nine deaths out of 2.7 million ... Other forms of thrombosis, such as the more common pulmonary embolism, may also occur. Arterial thrombosis has also been ...

https://en.wikipedia.org/wiki/Embolic_and_thrombotic_events_after_COVID-19_vaccination

Rosendaal FR, Reitsma PH (July 2009). "Genetics of venous thrombosis". Journal of Thrombosis and Haemostasis. 7 Suppl 1: 301-4 ... A central venous catheter (CVC), also known as a central line(c-line), central venous line, or central venous access catheter, ... venous thrombosis) including upper extremity deep vein thrombosis. It is thought this risk stems from activation of clotting ... "Central venous access sites for the prevention of venous thrombosis, stenosis and infection". The Cochrane Database of ...

https://en.wikipedia.org/wiki/Central_venous_catheter

López JA, Chen J (2009). "Pathophysiology of venous thrombosis". Thrombosis Research. 123 Suppl 4 (Suppl 4): S30-4. doi:10.1016 ... Bovill EG, van der Vliet A (2011). "Venous valvular stasis-associated hypoxia and thrombosis: what is the link?". Annual Review ... It is also implicated in the formation of deep vein thrombosis. As a result of activation, enthothelium releases Weibel-Palade ... Thrombosis, and Vascular Biology. 36 (6): 1090-100. doi:10.1161/ATVBAHA.115.306964. PMC 4882253. PMID 27127201. Alom-Ruiz SP, ...

https://en.wikipedia.org/wiki/Endothelial_activation

Rosendaal FR (2005). "Venous thrombosis: the role of genes, environment, and behavior". Hematology Am. Soc. Hematol. Educ. ... Rosendaal FR, Reitsma PH (July 2009). "Genetics of Venous Thrombosis". J. Thromb. Haemost. 7 Suppl 1: 301-304. doi:10.1111/j. ... Zakai, NA; McClure, LA (October 2011). "Racial differences in venous thromboembolism". Journal of Thrombosis and Haemostasis ( ... Behind non-O blood type and factor V Leiden, prothrombin G20210A is one of the most common genetic risk factors for venous ...

https://en.wikipedia.org/wiki/Prothrombin_G20210A

"Chapter 2: Risk Factors for Venous Thrombosis" (PDF). American Venous Forum. Archived from the original (PDF) on 27 September ... Venous stasis can occur during the long periods of not moving. Thrombosis prevention is also recommended during air travel. ... 2016). "Wells criteria for DVT is a reliable clinical tool to assess the risk of deep venous thrombosis in trauma patients". ... Studies of the pathophysiologic mechanisms for the increased risk of Venous thrombosis embolism or VTE after long-distance ...

https://en.wikipedia.org/wiki/Thrombosis_prevention

Martin, J. P. (May 1944). "Venous Thrombosis in the Central Nervous System". Proc R Soc Med. 37 (7): 383-392. doi:10.1177/ ... Martin, J. P. (5 April 1941). "Cerebral Venous Thrombosis after Childbirth". Br Med J. 1 (4187): 534-535. doi:10.1136/bmj. ... with H. L. Sheehan: Martin, J. P.; Sheehan, H. L. (25 April 1942). "Puerperal Cerebral Thrombosis". Br Med J. 1 (4242): 538-539 ... with H. L. Sheehan: Martin, J. P.; Sheehan, H. L. (8 March 1941). "Primary Thrombosis of Cerebral Veins (following Childbirth ...

https://en.wikipedia.org/wiki/James_Purdon_Martin

Prevention of postoperative deep venous thrombosis. Diagnosis of deep venous thrombosis] , Request PDF". "[Doppler ultrasonic ...

https://en.wikipedia.org/wiki/Paolo_Antonio_Boccasanta

"Contraceptive pills and venous thrombosis". The Cochrane Database of Systematic Reviews (3): CD010813. doi:10.1002/14651858. ... In particular, this can manifest as a deep vein thrombosis or pulmonary embolism. However, the risk with low-dose combined ... as whether the mother is breastfeeding and whether she has other medical conditions including superficial venous thrombosis and ... However, those containing higher doses of estrogen are associated with an increase in venous and arterial thromboembolism. In ...

https://en.wikipedia.org/wiki/Combined_hormonal_contraception

An elevated D-dimer in the elderly population has no predictive value for deep venous thrombosis. Signs and symptoms of DVT in ... Baker, W.F. Jr (1998). "Diagnosis of deep venous thrombosis and pulmonary embolism". Med. Clin. North Am. 82 (3, May): 459-476 ... Urbano, Frank L. (2001). "Review of Clinical Signs: Homans' Sign in the Diagnosis of Deep Venous Thrombosis" (PDF). Hospital ... Urbano, Frank (March 2001). "Homans' Sign in the Diagnosis of Deep Venous Thrombosis" (PDF). Hospital Physician. Archived from ...

https://en.wikipedia.org/wiki/Homans_sign

Sacerdoti D, Serianni G, Gaiani S, Bolognesi M, Bombonato G, Gatta A (March 2007). "Thrombosis of the portal venous system". ... is known as hepatic vein thrombosis or Budd-Chiari syndrome. Portal vein thrombosis causes upper abdominal pain, possibly ... Portal vein thrombosis (PVT) is a vascular disease of the liver that occurs when a blood clot occurs in the hepatic portal vein ... If portal vein thrombosis develops due to pylephlebitis, signs of infection such as fever, chills, or night sweats may be ...

https://en.wikipedia.org/wiki/Portal_vein_thrombosis

It is used in ultrasonography of deep venous thrombosis, wherein absence of vein compressibility is a strong indicator of ... Kearon, Clive; Julian, JA; Newman, TE; Ginsberg, JS (1998). "Noninvasive Diagnosis of Deep Venous Thrombosis". Annals of ... Compression ultrasonography has both high sensitivity and specificity for detecting proximal deep vein thrombosis in ... while ultrasonography of chronic venous insufficiency of the legs focuses on more superficial veins to assist with planning of ...

https://en.wikipedia.org/wiki/Medical_ultrasound

Baglin T (August 2011). "Using the laboratory to predict recurrent venous thrombosis". Int J Lab Hematol. 33 (4): 333-42. doi: ... Kyrle PA, Rosendaal FR, Eichinger S (December 2010). "Risk assessment for recurrent venous thrombosis". Lancet. 376 (9757): ... "From Classical Laboratory Parameters to Novel Biomarkers for the Diagnosis of Venous Thrombosis". Int J Mol Sci. 21 (6): 1920. ... menopausal hormone therapy and risk of venous thrombosis: The Women's Health Initiative". Res Pract Thromb Haemost. 2 (2): 310- ...

https://en.wikipedia.org/wiki/Coagulation_activation_marker

For patients with central venous access, a wide variation in the incidence of vein thrombosis (1 to 66 percent) is reported and ... "Catheter-related upper extremity venous thrombosis". uptodate.com. Retrieved 11 February 2016. (Orphaned articles from March ... Central venous catheters are the primary modality used for delivery of chemotherapeutic agents. The duration of central venous ... "Central Venous Catheters". Webmd. Retrieved 11 February 2016. "Central Venous Catheters". cancer.org. Retrieved 11 February ...

https://en.wikipedia.org/wiki/Vascular_access_for_chemotherapy

"Venous stasis and deep-vein thrombosis." Br J Surg. 1972 Sep;59(9):713-717. Description of pneumatic compression devices ... prevention and management of chronic venous disease, Thrombophilia and Venous Thromboembolism and The prevention of Venous ... 1994). Prevention of Venous Thromboembolism, Med-Orion Publishing. ISBN 978-9963-592-52-4 Belcaro G. et al. (1995). Venous ... He was chairman of the Committee of the American Venous Forum that created the CEAP classification of chronic venous disease. ...

https://en.wikipedia.org/wiki/Andrew_Nicolaides

Clinical examinations revealed cerebral venous thrombosis. He died on 28 July, aged 45. He left a 24-year-old son, whom he had ...

https://en.wikipedia.org/wiki/Rodrigo_Rodrigues_(TV_host)

Kitchens CS (2011). "How I treat superficial venous thrombosis". Blood. 117 (1): 39-44. doi:10.1182/blood-2010-05-286690. PMID ... For example, deep vein thrombosis of the femoral vein can cause pulmonary embolism, with a higher risk when the thrombus is ... The femoral vein is often used to place central venous lines. This is associated with a significant risk of infection. The ... In particular, the femoral vein is clinically a deep vein, where deep vein thrombosis indicates anticoagulant or thrombolytic ...

https://en.wikipedia.org/wiki/Femoral_vein

Kitchens CS (2011). "How I treat superficial venous thrombosis". Blood. 117 (1): 39-44. doi:10.1182/blood-2010-05-286690. PMID ... In particular, the adjacent femoral vein is clinically a deep vein, where deep vein thrombosis indicates anticoagulant or ... which has resulted in patients with femoral thrombosis being denied proper treatment. Therefore, the terms subsartorial artery ...

https://en.wikipedia.org/wiki/Femoral_artery

Recent studies describe the co-occurrence between coeliac disease, in which IBD is common in venous thrombosis. A study of ... Srirajaskanthan R, Winter M, Muller AF (2005). "Venous thrombosis in inflammatory bowel disease". European Journal of ... leg venous thrombosis, and heterozygosity for factor V Leiden". J. Gastroenterol. 37 (9): 761-762. doi:10.1007/s005350200126. ... "The factor V Leiden mutation increases the risk of venous thrombosis in patients with inflammatory bowel disease". ...

https://en.wikipedia.org/wiki/Gluten-sensitive_enteropathy–associated_conditions

Venous thrombosis associated with drainage from the brain (cerebral venous sinus thrombosis), eyes (retinal vein thrombosis), ... renal vein thrombosis), and ovaries (ovarian vein thrombosis) are more unusual forms of venous thrombosis and they are ... Deep vein thrombosis (DVT) is a type of venous thrombosis involving the formation of a blood clot in a deep vein, most commonly ... VTE, along with superficial vein thrombosis, are common types of venous thrombosis. DVT is classified as acute when the clots ...

https://en.wikipedia.org/wiki/Deep_vein_thrombosis

Southwick, FS; Richardson EP, Jr; Swartz, MN (March 1986). "Septic thrombosis of the dural venous sinuses". Medicine. 65 (2): ... This is a rare disorder and can be of two types-septic cavernous thrombosis and aseptic cavernous thrombosis. The most common ... "Guidelines Cavernous sinus thrombosis" (PDF). "Cavernous sinus thrombosis - NHS Choices". www.nhs.uk. NHS Choices. Retrieved 27 ... Cavernous sinus thrombosis (CST) is the formation of a blood clot within the cavernous sinus, a cavity at the base of the brain ...

https://en.wikipedia.org/wiki/Cavernous_sinus_thrombosis

Budd-Chiari syndrome (supra-hepatic venous thrombosis). Her cure was recognised on 31 May 1963. Visited Lourdes: 5 June 1958. ...

https://en.wikipedia.org/wiki/Lourdes_Medical_Bureau

... thrombosis Dural venous sinuses Yasuda; et al. (Jun 2008). "Microsurgical anatomy and approaches to the ... forming a cavernous sinus thrombosis. From there the infection may spread to the dural venous sinuses. Infections may also be ... The cavernous sinus is one of the dural venous sinuses of the head. It is a network of veins that sit in a cavity. It sits on ... bacterial infection causing cavernous sinus thrombosis, aseptic cavernous sinus thrombosis, idiopathic granulomatous disease ( ...

https://en.wikipedia.org/wiki/Cavernous_sinus

452 Portal vein thrombosis 453 Other venous embolism and thrombosis 453.4 Deep vein thrombosis, unspec. 453.41 Deep vein ... thrombosis, proximal 453.42 Deep vein thrombosis, distal 453.9 Venous embolism, unspec. site 454 Varicose veins of lower ... cerebral arteries 434.0 Cerebral thrombosis 434.00 Cerebral thrombosis without cerebral infarction 434.01 Cerebral thrombosis ... aneurysm nonruptured 437.4 Cerebral arteritis 437.5 Moyamoya disease 437.6 Nonpyogenic thrombosis of intracranial venous sinus ...

https://en.wikipedia.org/wiki/List_of_ICD-9_codes_390–459:_diseases_of_the_circulatory_system

... of those with Cushing's syndrome has tendency to develop venous thrombosis. Other factors such as surgery and obesity also ... Occasionally, determining the ACTH levels in various veins in the body by venous catheterization, working towards the pituitary ... increases the chance of getting thrombosis. For more information on the form in horses, see pituitary pars intermedia ...

https://en.wikipedia.org/wiki/Cushing's_syndrome

She said that the risk of a cerebral venous sinus thrombosis blood clot was "potentially as high as one in 100,000, much higher ...

https://en.wikipedia.org/wiki/Shelley_Deeks

... an uncommon severe form of deep venous thrombosis. Phlegmasia alba dolens, resulting in a white appearance of the leg. This ...

https://en.wikipedia.org/wiki/Phlegmasia

In 2010, he published the book Principles of venous hemodynamics detailing hemodynamic concepts of the venous insufficiency and ... In particular, he worked on the criteria of arterial stenosis of limbs and carotids, Carotid pre-thrombosis, the Pressure- ... According to this theory, varicose veins are not, as well as edema and ulcers, the cause of the venous insufficiency, but the ... The CHIVA technique as a treatment of venous insufficiency is now accepted as the standard of care in those situations where it ...

https://en.wikipedia.org/wiki/Claude_Franceschi

Corona-Hernandes syndrome Capillary leak syndrome Capillary leak syndrome with monoclonal gammopathy Capillary venous ... gigantism jaw cysts Cerebral hypoxia Cerebral malformations hypertrichosis claw hands Cerebral palsy Cerebral thrombosis ... Caudal duplication Caudal regression syndrome Causalgia Cavernous hemangioma Cavernous lymphangioma Cavernous sinus thrombosis ...

https://en.wikipedia.org/wiki/List_of_diseases_(C)

A high incidence of thrombosis and venous thromboembolism occurs in people transferred to intensive care units with COVID‑19 ...

https://en.wikipedia.org/wiki/COVID-19

Kalbag R M, Woolf A L (1967) Cerebral Venous Thrombosis, with Special Reference to Primary Aseptic Thrombosis. Oxford, Oxford ... especially cerebral venous thrombosis. Puerperal women are liable to thrombosis, especially thrombophlebitis of the leg and ... Lanska D J, Kryscio R J (2000) Risk factors for peripartum and postpartum stroke and intracranial venous thrombosis. Stroke 31 ... Srinavasan K (1988) Puerperal cerebral venous and arterial thrombosis. Seminars in Neurology 8:222-225. Jack T M (1982) Post- ...

https://en.wikipedia.org/wiki/Postpartum_psychosis

Lippi G, Cervellin G, Franchini M, Favaloro EJ (November 2010). "Biochemical markers for the diagnosis of venous ... thrombosis, and other cardiovascular complications. It is a marker of thrombin generation and indicates hypercoagulability. The ...

https://en.wikipedia.org/wiki/Activated_protein_C–protein_C_inhibitor

Nearly 60% develop phlebitis which often progresses to deep vein thrombosis in more than 50% of patients. The venous ... Atrophie blanche Compression stockings Lipodermatosclerosis Venography Venous stasis Venous ulcer "Chronic Venous Insufficiency ... and ambulatory venous pressures, which provides a global assessment of venous competence. Venous plethysmography can assess for ... Venous ulcers are common and very difficult to treat. Chronic venous ulcers are painful and debilitating. Even with treatment, ...

https://en.wikipedia.org/wiki/Chronic_venous_insufficiency

Death Serious complications include deep vein thrombosis, organ perforation, bleeding, and infection. Death occurs in about one ... Fibro-Lipo-Lymph-Aspiration With a Lymph Vessel Sparing Procedure to Treat Advanced Lymphedema After Multiple Lymphatic-Venous ... "Fibro-Lipo-Lymph-Aspiration With a Lymph Vessel Sparing Procedure to Treat Advanced Lymphedema After Multiple Lymphatic-Venous ... Fibro-Lipo-Lymph-Aspiration With a Lymph Vessel Sparing Procedure to Treat Advanced Lymphedema After Multiple Lymphatic-Venous ...

https://en.wikipedia.org/wiki/Liposuction

... thrombosis and nerve compression syndrome of cranial nerves XI and XII. One death case appeared in the scientific literature, ... Most of the venous problems in MS patients have been reported to be truncular venous malformations, including azygous stenosis ... MS is also more common in women, while venous diseases are more common in men. Venous pathology is commonly associated with ... A similar condition involving the head and neck venous system may cause chronic cerebro-spinal venous insufficiency (CCSVI) and ...

https://en.wikipedia.org/wiki/Chronic_cerebrospinal_venous_insufficiency_controversy

The resulting complications may include suture diastasis, venous sinus thrombosis, and epidural hematoma. In young children, ... or they involve a venous sinus groove or vascular channel. ...

https://en.wikipedia.org/wiki/Skull_fracture

Elliott, C. Gregory (2000). "The Diagnostic Approach to Deep Venous Thrombosis: Diagnostic Tests for Deep Vein Thrombosis". ... but of most importance is the detection of venous thrombosis. The most reliable sign of thrombosis (even when a good image and ... The inability to compress the vein is one of the more reliable indications of venous thrombosis. There is a simplified ... Hollyoak, Maureen; Woodruff, Peter; Muller, Michael; Daunt, Nicholas; Weir, Paula (2001). "Deep venous thrombosis in ...

https://en.wikipedia.org/wiki/Ultrasonography_of_deep_vein_thrombosis

Paris Thrombosis case-control Study". Arteriosclerosis, Thrombosis, and Vascular Biology. 20 (3): 892-8. doi:10.1161/01.ATV. ... regulatory region of the tissue factor gene and the risk of myocardial infarction and venous thromboembolism: the ECTIM and ...

https://en.wikipedia.org/wiki/TATA_box

While an endovascular BCI benefits from avoiding craniotomy for insertion, risks such as clotting and venous thrombosis are ... The procedure is most similar to how venous sinus stents are placed for the treatment of idiopathic intracranial hypertension. ...

https://en.wikipedia.org/wiki/Brain–computer_interface

Additionally, shared dural venous sinuses is usually absent, or, if it is present, negligible. These twins usually undergo ... and dura mater-because separating shared vessels can lead to thrombosis, air embolism, cerebral infarction, and hemorrhage. ... Partial CPT was defined as "lacking substantial shared dural venous sinuses", whereas total CPT "share a large portion of their ... Stone and Goodrich define partial craniopagus twins as lacking substantial shared dural venous sinuses, with limited surface ...

https://en.wikipedia.org/wiki/Craniopagus_twins

Physical findings may include absent breath sounds on one side of the chest, jugular venous distension, and tracheal deviation ... Risk factors include deep vein thrombosis, recent surgery, cancer, and previous thromboembolism. It must always be considered ... Cardiac tamponade presents with dyspnea, tachycardia, elevated jugular venous pressure, and pulsus paradoxus. The gold standard ...

https://en.wikipedia.org/wiki/Shortness_of_breath

Another potentially deadly threat to respiration is deep venous thrombosis (DVT), in which blood forms a clot in immobile limbs ... found to be less likely to develop complete injuries and some complications such as pressure sores and deep vein thrombosis, ...

https://en.wikipedia.org/wiki/Spinal_cord_injury

... venous outflow obstruction (e.g. cerebral venous sinus thrombosis). Nonpenetrating and penetrating cranial trauma can also be ... In addition, venous malformations are associated with hemorrhage. In the elderly population, amyloid angiopathy is associated ... angiopathy Intracranial neoplasm Coagulopathy Hemorrhagic transformation of an ischemic stroke Cerebral venous thrombosis ...

https://en.wikipedia.org/wiki/Intraparenchymal_hemorrhage

Spontaneous venous thromboses occurred in some patients, sometimes accompanied with spontaneous intracranial bleeding in the ...

https://en.wikipedia.org/wiki/TEMPI_syndrome

The path that blood take is as follows: venous blood passes through the vena cava and is moved into the right ventricle of the ... Aird WC (July 2011). "Discovery of the cardiovascular system: from Galen to William Harvey". Journal of Thrombosis and ...

https://en.wikipedia.org/wiki/History_of_medicine

... venous, or small vessel thrombosis - other than superficial venous thrombosis - in any tissue or organ by objective validated ... In APS patients, the most common venous event is deep vein thrombosis of the lower extremities, and the most common arterial ... Based on this statement, Definite CAPS diagnosis requires: a) Vascular thrombosis in three or more organs or tissues and b) ... "Venous thromboembolic diseases: diagnosis, management and thrombophilia testing". www.nice.org.uk. National Institute for ...

https://en.wikipedia.org/wiki/Antiphospholipid_syndrome

Seligsohn U (Jul 2007). "Factor XI in haemostasis and thrombosis: past, present and future". Thrombosis and Haemostasis. 98 (1 ... November 2021). "Milvexian for the Prevention of Venous Thromboembolism". The New England Journal of Medicine. 385 (23): 2161- ... High levels of factor XI have been implicated in thrombosis, although it is uncertain what determines these levels and how ... Walsh PN (Jul 2001). "Roles of platelets and factor XI in the initiation of blood coagulation by thrombin". Thrombosis and ...

https://en.wikipedia.org/wiki/Factor_XI

... which is used for the prevention of blood clots and in the treatment of deep venous thrombosis. Lehmann studied under Torsten ...

https://en.wikipedia.org/wiki/Jörgen_Lehmann

This may lead to complications such as thrombosis. For example patients that have spinal dural fistulas can experience venous ... The external vertebral venous plexuses is also available for the internal vertebral venous plexus to communicate with. Anterior ... There is a very limited availability to research the spinal venous system as a whole, which in turn leads to an even smaller ... One of the few major studies of the venous anatomy was conducted by Armin Thron, which can be seen in his published "Vascular ...

https://en.wikipedia.org/wiki/Anterior_spinal_veins

Their extended circulation time means that they are able to be used for both arterial and venous mapping. Additional uses ... Gadofosveset enhanced MR phlebography for detecting pelvic and deep vein leg thrombosis, Vasa, 2011;40:315-9 Haneder S, ...

https://en.wikipedia.org/wiki/Blood_pool_agent

... venous thromboembolism, thrombosis of vascular access, and tumor progression or recurrence. To avoid side effects, it is ...

https://en.wikipedia.org/wiki/Darbepoetin_alfa

Deep venous thrombosis Disseminated intravascular coagulation Doucas and Kapetanakis pigmented purpura Drug-induced purpura ... Cavernous venous malformation Congenital cartilaginous rest of the neck (cervical accessory tragus, wattle) Congenital erosive ... Venous lake (phlebectasis) Wildervanck syndrome Xanthelasmoidal mastocytosis Zosteriform metastasis Dermatitis is a general ... Venous insufficiency ulceration Waldenström hyperglobulinemic purpura (purpura hyperglobulinemica) Waldenström ...

https://en.wikipedia.org/wiki/List_of_skin_conditions

Mesenteric venous thrombosis (MVT) is a blood clot in one or more of the major veins that drain blood from the intestine. The ... Mesenteric venous thrombosis (MVT) is a blood clot in one or more of the major veins that drain blood from the intestine. The ... Outlook depends on the cause of the thrombosis and any damage to the intestine. Getting treatment for the cause before the ...

https://medlineplus.gov/ency/article/001157.htm

Thrombosis of the venous channels in the brain is an uncommon cause of cerebral infarction relative to arterial disease, but it ... encoded search term (Cerebral Venous Thrombosis) and Cerebral Venous Thrombosis What to Read Next on Medscape ... Increased risk of cerebral venous sinus thrombosis with third- generation oral contraceptives. Cerebral Venous Sinus Thrombosis ... Knowledge of the anatomy of the venous system is essential in evaluating patients with cerebral venous thrombosis (CVT), since ...

https://www.medscape.com/answers/1162804-41818/what-is-the-global-incidence-of-cerebral-venous-thrombosis-cvt

... is a manifestation of venous thromboembolism (VTE). Although most DVT is occult and resolves spontaneously without complication ... Deep venous thrombosis (DVT). The computed tomography venogram shows bilateral deep venous thrombosis (arrows). ... encoded search term (Deep Venous Thrombosis (DVT)) and Deep Venous Thrombosis (DVT) What to Read Next on Medscape ... Determinants of chronic venous disease after acute deep venous thrombosis. J Vasc Surg. 1998 Nov. 28(5):826-33. [QxMD MEDLINE ...

https://emedicine.medscape.com/article/1911303-differential

... venous thrombosis leads to pulmonary embolism, which can be fatal. Persons with an initial venous thrombosis are at increased ... Factor V Leiden and Venous Thrombosis Objectives. alert icon Archived: This Page Is No Longer Being Updated This web page is ... Venous thrombosis is an important cause of morbidity; incidence is low in young people but increases with age to 1% per year in ... Increased risk of venous thrombosis in OC users who are carriers of factor V Leiden mutation. Lancet 1994;344:1453-157. ...

https://www.cdc.gov/genomics/hugenet/CaseStudy/FVL/FVLview.htm

WHO Research Into Global Hazards of Travel Project; World Health Organization (‎World Health OrganizationWorld Health Organization, 2007)‎ ...

https://extranet.who.int/iris/restricted/browse?authority=Venous+Thrombosis&type=mesh

... Headache. 1989 Feb;29(2):82-5. doi: 10.1111/j.1526- ... The association of migraine-like visual phenomena with cerebral venous thrombosis may provide insight into the pathogenesis of ...

https://pubmed.ncbi.nlm.nih.gov/2708040/?dopt=Abstract

MAXIMUM 150 WORDS: Remember: front load your paragraphs! This content should include a strong opening sentence describing the health topic in the Eastern Mediterranean (include key words "Eastern Mediterranean" and health topic name for search engine optimization). You should focus on the issue as it relates to the Region and the magnitude of problem in the region, as well as a brief mention of current situation/problem.. ...

https://www.emro.who.int/health-topics/venous-thrombosis/

... is a manifestation of venous thromboembolism (VTE). Although most DVT is occult and resolves spontaneously without complication ... Deep venous thrombosis (DVT). The computed tomography venogram shows bilateral deep venous thrombosis (arrows). View Media ... Deep venous thrombosis (DVT). The computed tomography venogram shows bilateral deep venous thrombosis (arrows). ... encoded search term (Deep Venous Thrombosis (DVT)) and Deep Venous Thrombosis (DVT) What to Read Next on Medscape ...

https://emedicine.medscape.com/article/1911303-overview

... This site maintained by the Center for Outcomes ... It provides information pertaining to the best practices in preventing deep venous thrombosis and pulmonary embolus. This ... Disciplines with similar materials as Best Practices in Preventing Deep Venous Thrombosis and Pulmonary Embolus ... It provides information pertaining to the best practices in preventing deep venous thrombosis and pulmonary embolus. This ...

https://www.merlot.org/merlot/viewMaterial.htm?id=594581

Unusual venous thrombosis in a 35-year-old man. Ami Schattner. CMAJ January 07, 2014 186 (1) 51-55; DOI: https://doi.org/ ...

https://www.cmaj.ca/content/186/1/51/tab-article-info

Deep venous thrombosis is a prevalent medical problem, with an annual incidence of 80 cases per 100,000 individuals. Can you ... Fast Five Quiz: Can You Detect and Appropriately Treat Deep Venous Thrombosis? - Medscape - May 22, 2015. ... Fast Five Quiz: Can You Detect and Appropriately Treat Deep Venous Thrombosis?. ... The length of anticoagulant therapy depends on the site of thrombosis and on the ongoing presence of risk factors. For the ...

https://reference.medscape.com/viewarticle/845042_5

Thrombosis. Venous Thrombosis. Embolism and Thrombosis. Vascular Diseases. Cardiovascular Diseases. Heparin. Rivaroxaban. ... any thrombosis at a new site including cerebral venous thrombosis in a separate localization from index event ... Study of Rivaroxaban for CeREbral Venous Thrombosis (SECRET). The safety and scientific validity of this study is the ... During the pilot phase, 50 adult patients within 14 days of symptomatic cerebral venous thrombosis diagnosis will be randomized ...

https://www.clinicaltrials.gov/show/NCT03178864

Cases of Cerebral Venous Sinus Thrombosis with Thrombocytopenia after Receipt of the Johnson & Johnson COVID-19 Vaccine ... This COCA Call will present the latest evidence on cerebral venous sinus thrombosis (CVST) with thrombocytopenia associated ... Johnson & Johnson/Janssen COVID-19 Vaccine and Cerebral Venous Sinus Thrombosis with Thrombocytopenia - Update for Clinicians ... Johnson & Johnson/Janssen COVID-19 Vaccine and Cerebral Venous Sinus Thrombosis with Thrombocytopenia - Update for Clinicians ...

https://emergency.cdc.gov/coca/calls/2021/callinfo_041521.asp

There is still some controversy over the best practice for prevention of deep vein thrombosis (DVT) during laparoscopic surgery ... Guidelines for deep venous thrombosis prophylaxis during laparoscopic surgery. Surg Endosc. 2007;21(6):1007-9. ... The overall incidence of clinically evident deep venous thrombosis (DVT) was 1.6% without prophylaxis. Two randomized studies ... Risk assessment as a guide for the prevention of the many faces of venous thromboembolism. Am J Surg. 2010;199(1 Suppl):S3-10. ...

https://www.sages.org/publications/guidelines/guidelines-for-deep-venous-thrombosis-prophylaxis-during-laparoscopic-surgery/

Pearls & Oy-sters: Postdural Puncture Headache, Cerebral Sinus Venous Thrombosis, and Reversible Cerebral Vasoconstriction ... Pearls & Oy-sters: Arteriovenous Malformation With Sinus Thrombosis and Thalamic HemorrhageUnusual Cause of Parkinsonism and ...

https://www.neurology.org/collection/cerebral_venous_thrombosis

... it cannot be used to detect venous thromboembolism (VTE) because of its low positive predictive value (PPV). This study aims to ... i,Objective,/i,. While D-dimer can successfully diagnose venous thrombosis due to its excellent negative predictive value (NPV ... Venous thromboembolism (VTE) which includes deep venous thrombosis (DVT) and pulmonary embolism (PE) is a critical complication ... D-Dimer Combined with Fibrinogen Predicts the Risk of Venous Thrombosis in Fracture Patients. Chaohui Lin. ,1,2Yifan Chen. ,2 ...

https://www.hindawi.com/journals/emi/2020/1930405/

Isolated intracranial hypertension as the only sign of cerebral venous thrombosis. Valérie Biousse, Alain Ameri, Marie-Germaine ... Isolated intracranial hypertension as the only sign of cerebral venous thrombosis. Valérie Biousse, Alain Ameri, Marie-Germaine ... Background: Cerebral venous thrombosis (CVT) is often overlooked when intracranial hypertension (ICH) is isolated, hence ... Conclusions: Central venous thrombosis (CVT) can present with all the classical criteria for idiopathic intracranial ...

https://n.neurology.org/content/53/7/1537?ijkey=7d1071bd10085ec1deec204673130044096a007e&keytype2=tf_ipsecsha

Venous thromboembolism constitutes a clinical spectrum encompassing deep venous thrombosis (DVT) and pulmonary embolism (PE). ... Outpatient Treatment of Deep Venous Thrombosis In Managed Care. March 23, 2021. by Paul Lendner ... Deep Venous Thrombosis: Outpatient Therapy With Low-Molecular-Weight Heparin. *Reimbursement of Enoxaparin for Outpatient ... Reimbursement Strategies in an Outpatient-Based Disease Management Program for the Treatment of Deep Venous Thrombosis in an ...

https://www.managedcaremag.com/supplements/1999/

Ultrasound Assessment and Mapping of the Superficial Venous System * Understanding and Interpreting Spectral Waveforms in the ... Identify acute versus chronic deep vein thrombosis. Describe deep, perforator, and superficial vein anatomy in the lower ... Ultrasound Assessment and Mapping of the Superficial Venous System (Category A version) ...

https://www.iame.com/online-courses/vascular/case-series-lower-extremity-venous-thrombosis

... Jan 1, 2017 , Magazine: ... events following isolated noncatheter-associated upper extremity deep venous thrombosis (non-CA-UEDVT) to better inform future ... Any patient with an indwelling catheter or pacemaker lead at the DVT site and at the time of thrombosis was considered to have ... CITATION J Vasc Surg Venous Lymphat Disord. 2017 Jan;5(1):18-24.e1. doi: 10.1016/j.jvsv.2016.08.002. Epub 2016 Oct 27 ...

https://www.cun.es/en/research/scientific-publications/analysis-noncatheter-associated-upper-extremity-deep-venous-thrombosis-riete-registry

The value of occlusion plethysmography and stress venous pressure in functional diagnosis following leg vein thrombosis]. ... Venous plethysmography in the diagnosis of deep venous thrombosis and postthrombotic venous incompetence. ... Venous occlusion plethysmography for the detection of venous thrombosis.. *[The flow-volume curve. Expression of emptying as a ... Venous stasis and deep vein thrombosis prophylaxis during laparoscopic fundoplication].. *Venous plethysmography in the ...

https://www.unboundmedicine.com/medline/citation/2291275/%5BThe_value_of_occlusion_plethysmography_and_stress_venous_pressure_in_functional_diagnosis_following_leg_vein_thrombosis%5D_

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Centers RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.. ...

https://casereports.bmj.com/content/15/9/e250711.info

Typical MRI imaging features of dural venous sinus thrombosis. The most sensitive MRI sequences without contrast injection for ... Typical MRI imaging features of dural venous sinus thrombosis. The most sensitive MRI sequences without contrast injection for ... Patients with untreated dural venous sinus thrombosis are at risk of developing infarction with the potential of hemorrhagic ... Kalioras E, Dural venous sinus thrombosis. Case study, Radiopaedia.org (Accessed on 01 Dec 2022) https://doi.org/10.53347/rID- ...

https://radiopaedia.org/cases/dural-venous-sinus-thrombosis-22?iframe=true&lang=us

Venous Thrombosis - related terms, definitions and short phrases grouped together in the form of Encyclopedia article. ... Venous thrombosis of the legs is diagnosed by ultrasound. (Web site). High Risk. *Preventing deep venous thrombosis (DVT) is ... MESENTERIC VENOUS THROMBOSIS. D-DIMERS. RECURRENT VENOUS THROMBOSIS. ATHEROSCLEROSIS. SYMPTOMS. HEADACHE. SUPERFICIAL. ARTERIAL ... Rosendaal F. Venous thrombosis: a multicausal disease. (Web site). Portal Venous Thrombosis. *Polycythemia vera should be ...

http://keywen.com/en/VENOUS_THROMBOSIS

intracranial (see also Thrombosis, brain) 434.0. *. venous sinus (any) 325. *. nonpyogenic origin 437.6*. in pregnancy or ... 2015/16 ICD-10-CM I67.6 Nonpyogenic thrombosis of intracranial venous system ... intracranial venous sinus (any) 325. *. late effect - see category 326. *. nonpyogenic 437.6*. in pregnancy or puerperium 671.5 ... intracranial sinus (any) (venous) 325. *. late effect - see category 326. *. nonpyogenic 437.6*. in pregnancy or puerperium ...

http://www.icd9data.com/2015/Volume1/390-459/430-438/437/437.6.htm

https://www.emergency.cdc.gov/coca/calls/2021/callinfo_041521.asp

... was found in two studies to carry a 2-3 fold increased risk of venous thromboembolism relative to other alternative oral ... Venous thrombosis appears to double or triple with use of drospirenone-containing oral contraceptives Rene Gonzalez, Pharm.D. ... The venous thrombotic risk of oral contraceptives, effects of oestrogen dose and progestogen type: results of the MEGA study. ... Drospirenone, found in products such as Yaz® or Yasmin®, was found in two studies to carry a 2-3 fold increased risk of venous ...

http://clotcare.com/yaz_blood_clot_risk.aspx

DVT or Deep Venous Thrombosis) begins by showing a blood clot forming in a lower leg vein. As red blood cells flow through the ... vein, slower moving cells and other blood elements accumulate on the venous valves, creating a stationary blood clot, or ... This 3D medical animation depicting Deep Vein Thrombosis ( ... Deep Vein (Venous) Thrombosis (DVT) and Pulmonary Embolism (PE ... This 3D medical animation depicting Deep Vein Thrombosis (DVT or Deep Venous Thrombosis) begins by showing a blood clot forming ...

https://www.doereport.com/generateexhibit.php?ID=15138&I=

Dural venous sinus abnormalities are clinically important but can potentially be overlooked using various MRI techniques. This ... Dural Venous Sinus Thrombosis Of the 73 patients and 730 venous segments evaluated in this study, there were a total of 13 ... rates for dural venous sinus thrombosis were calculated per venous segment on SE T1-weighted imaging and 3D GRE T1-weighted ... TABLE 2: Interreader Concordance Rates for Dural Venous Sinus Thrombosis by Intrinsic T1 Hyperintensity on Unenhanced Spin-Echo ...

https://www.ajronline.org/doi/10.2214/AJR.12.9095

Management of venous thromboembolism: a clinical practice guideline from the American College of Physicians and the American Academy of Family Physicians. (medscape.com)
Oral rivaroxaban for symptomatic venous thromboembolism. (medscape.com)
Deep venous thrombosis (DVT) is a manifestation of venous thromboembolism (VTE). (medscape.com)
Deep venous thrombosis (DVT) and pulmonary embolism (PE) are manifestations of a single disease entity, namely, venous thromboembolism (VTE). (medscape.com)
Since the publication of the SAGES guidelines for venous thromboembolism (VTE) prophylaxis during laparoscopic surgery in 2007 (1) , the American College of Chest Physicians (ACCP) has published their comprehensive guidelines that address VTE prophylaxis for non-orthopedic surgery patients (2) . (sages.org)
While D-dimer can successfully diagnose venous thrombosis due to its excellent negative predictive value (NPV), it cannot be used to detect venous thromboembolism (VTE) because of its low positive predictive value (PPV). (hindawi.com)
Venous thromboembolism (VTE) which includes deep venous thrombosis (DVT) and pulmonary embolism (PE) is a critical complication of fracture patients. (hindawi.com)
Venous thromboembolism constitutes a clinical spectrum encompassing deep venous thrombosis (DVT) and pulmonary embolism (PE). (managedcaremag.com)
We sought to determine the risk factors for subsequent bleeding and recurrent venous thromboembolism (VTE) events following isolated noncatheter-associated upper extremity deep venous thrombosis (non-CA-UEDVT) to better inform future treatment decisions for this group of patients. (cun.es)
The RIETE registry (Registro Informatizado de Enfermedad TromboEmbólica [Computerized Registry of Patients with Venous Thromboembolism]) is a prospective international registry of patients with objectively confirmed symptomatic VTE. (cun.es)
Hormonal factors and risk of recurrent venous thrombosis: the prevention of recurrent venous thromboembolism trial. (keywen.com)
Drospirenone, found in products such as Yaz® or Yasmin®, was found in two studies to carry a 2-3 fold increased risk of venous thromboembolism relative to other alternative oral contraceptives containing levonorgestrel. (clotcare.com)
Both studies evaluated women between the ages 15-44 who were taking an oral contraceptive containing either levonorgestrel or drospirenone without any major risk factors for venous thromboembolism such as trauma, recent surgery, cancer, and prolonged immobility. (clotcare.com)
Although, the data seem compelling enough to suggest that dropirenone-containing oral contraceptives carry an increased risk of venous thromboembolism versus other oral contraceptives, actual event rates were small for both groups. (clotcare.com)
Risk of venous thromboembolism in users of oral contraceptives containing drospirenone or levonorgestrel: nested case-control study based on UK General Practice Research Database. (clotcare.com)
Risk of non-fatal venous thromboembolism in women using oral contraceptives containing drospirenone compared with women using oral contraceptives containing levonorgestrel: case-control study using United States claims data. (clotcare.com)
Association of venous thromboembolism and clozapine. (pneumotox.com)
In conclusion, venous thromboembolism recurrence rates are low and comparable to lower extremity DVT. (elsevier.com)
Venous thromboembolism (VTE) is a life-threatening cardiovascular syndrome that characterized by the imbalance of hemostasis and thrombosis and the formation of thrombi in the blood vessels. (biomedcentral.com)
Venous thromboembolism (VTE), including deep-vein thrombosis (DVT) and pulmonary embolism (PE), is the third most common acute cardiovascular syndrome and its disease burden is growing as the population and life expectancy expand [ 1 ]. (biomedcentral.com)
Prospective study of gamma' fibrinogen and incident venous thromboembolism: the Longitudinal Investigation of Thromboembolism Etiology (LITE). (cdc.gov)
Introduction: Epidemiological studies generally have not found plasma total fibrinogen to be a risk factor for venous thromboembolism (VTE), but several have reported associations between variants in the fibrinogen gamma gene (FGG) and VTE. (cdc.gov)
The highest estimates of excess cases per million vaccine doses were 7.5 for venous thromboembolism and 1.2 for heart attack. (umn.edu)

This COCA Call will present the latest evidence on cerebral venous sinus thrombosis (CVST) with thrombocytopenia associated with the administration of the Johnson & Johnson/Janssen COVID-19 vaccine. (cdc.gov)
Cerebral venous sinus thrombosis (CVST) is a possible severe complication of AM, with an estimated incidence rate of 0-2.7% [ 3 ]. (biomedcentral.com)
Cerebral venous sinus thrombosis (CVST) is a rare neurovascular disorder with highly variable manifestations and clinical courses. (biomedcentral.com)
Cerebral venous sinus thrombosis (CVST) is a rare neurovascular disorder accounting for approximately 0.5% of strokes, occurring more frequently in young adults [ 1 ]. (biomedcentral.com)
Cerebral venous sinus thrombosis (CVST) is a clot in the venous drainage system of the brain and can present to ophthalmology. (eyewiki.org)
If unfavorable conditions exist, a CVST may lead to increased venous and capillary pressure and a breakdown in the blood brain barrier with resultant vasogenic edema, cytotoxic edema, and hemorrhage. (eyewiki.org)
Cerebral venous sinus thrombosis (CVST) constitutes a small proportion of stroke. (jofem.org)
Cerebral venous sinus thrombosis (CVST) is a rare disease accounting for less than 1% of all strokes. (jofem.org)
The CDC and FDA said in a statement that in the known six cases, "a type of blood clot called cerebral venous sinus thrombosis (CVST) was seen in combination with low levels of blood platelets (thrombocytopenia). (11alive.com)

Coagulation studies, factor V Leiden, and anticardiolipin antibodies in 40 cases of cerebral venous thrombosis. (keywen.com)

For example, cerebral infarction may occur with cortical vein or sagittal sinus thrombosis secondary to tissue congestion with obstruction. (medscape.com)
Lateral sinus thrombosis may be associated with headache and a pseudotumor cerebri-like picture. (medscape.com)
Extension into the jugular bulb may cause jugular foramen syndrome, while cranial nerve palsies may be seen in cavernous sinus thrombosis as a compressive phenomenon. (medscape.com)
Cerebral hemorrhage also may be a presenting feature in patients with venous sinus thrombosis. (medscape.com)
Imaging procedures have led to easier recognition of venous sinus thrombosis (see the images below), offering the opportunity for early therapeutic measures. (medscape.com)
Left lateral sinus thrombosis demonstrated on magnetic resonance venography (MRV). (medscape.com)
CDC recommends pausing the use of the J&J COVID-19 vaccine until the Advisory Committee on Immunization Practices is able to further review these cerebral venous sinus thrombosis cases in the context of thrombocytopenia and assess their potential significance. (cdc.gov)
Typical MRI imaging features of dural venous sinus thrombosis . (radiopaedia.org)
Whereas a T1-weighted sequence with contrast injection is the most sensitive and specific for the imaging diagnosis of dural venous sinus thrombosis. (radiopaedia.org)
Patients with untreated dural venous sinus thrombosis are at risk of developing infarction with the potential of hemorrhagic transformation. (radiopaedia.org)
Dural venous sinus abnormalities are clinically important but can potentially be overlooked using various MRI techniques. (ajronline.org)
This study evaluates the diagnostic accuracy of spin-echo (SE) T1-weighted imaging, 3D gradient-recalled echo (GRE) T1-weighted imaging, and contrast-enhanced MR venography (MRV) for the detection of dural venous sinus thrombosis and transverse sinus (TS) stenosis. (ajronline.org)
Three neuroradiologists each evaluated these 219 total datasets in a randomized blinded fashion for the presence or absence of TS stenosis and for dural venous sinus thrombosis in each of 10 venous sinus segments (730 total segments). (ajronline.org)
Contrast-enhanced 3D GRE T1-weighted imaging is superior to SE T1-weighted imaging for the detection of dural venous sinus thrombosis and TS stenosis but does not substitute for dedicated MRV. (ajronline.org)
Hyperintensity on unenhanced SE T1-weighted imaging is unreliable for the detection of dural venous sinus thrombosis. (ajronline.org)
The clinical diagnosis of dural venous sinus thrombosis is often challenging because of its infrequency (annual incidence of 3-4 cases per 1 million individuals) and variable, nonspecific clinical presentation [ 1 , 2 ]. (ajronline.org)
Prompt diagnosis is crucial because early intervention, including anticoagulation and systemic or catheter-directed thrombolysis, is associated with favorable clinical outcomes, whereas hemorrhagic complications from dural venous sinus thrombosis can result in devastating neurologic outcomes [ 3 , 4 ]. (ajronline.org)
Stenosis of the dural venous sinuses-specifically, transverse sinus (TS) stenosis-has been highly associated with increased intracranial pressure (ICP) in the setting of idiopathic intracranial hypertension (IIH) [ 5 - 7 ]. (ajronline.org)
The diagnosis of IIH requires documentation of elevated opening pressure on lumbar puncture without evidence of other causes of elevated ICP including an intracranial mass lesion, hydrocephalus, and dural venous sinus thrombosis [ 8 ]. (ajronline.org)
Cerebral venous sinus thrombosis in children is a rare but potentially fatal complication of acute mastoiditis, one of the most common pediatric infectious diseases. (biomedcentral.com)
To discuss the possible clinical presentation, microbiology, and management, we here report the case of a child with otogenic cerebral venous sinus thrombosis and perform a literature review starting from 2011. (biomedcentral.com)
Brain computed tomography scan detected right sigmoid and transverse sinus thrombosis, as well as a subperiosteal abscess. (biomedcentral.com)
Cerebral venous sinus thrombosis is a rare but severe complication of acute otitis media and mastoiditis. (biomedcentral.com)
A contrast-enhanced (CE) computed tomography (CT) scan of the head showed bilateral mastoiditis with swelling of the adjacent right soft tissues, multiple abscesses, and a thrombosis of the right sigmoid sinus and of the distal portion of the right transverse sinus (Fig. 1 ). (biomedcentral.com)
Treatment of the sinus thrombosis was initiated on the day after surgery with subcutaneous low molecular weight heparin (LMWH) was administered at the standard dosage of 100 International Units (IU)/kg twice a day, to treat the sinus thrombosis. (biomedcentral.com)
Sagittal sinus thrombosis may present with motor deficits, bilateral deficits, and seizures. (emdocs.net)
Thrombosis of the left transverse sinus can present as aphasia. (emdocs.net)
Thrombosis of the deep venous sinus can cause behavioral symptoms due to lesions in the thalamus. (emdocs.net)
Venous Cerebral Dural Sinus Thromboses is a topic covered in the Johns Hopkins ABX Guide . (hopkinsguides.com)
Johns Hopkins Guide , www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540584/all/Venous_Cerebral_Dural_Sinus_Thromboses. (hopkinsguides.com)
Auwaerter P. Venous Cerebral Dural Sinus Thromboses. (hopkinsguides.com)
IMSEAR at SEARO: Cerebral venous sinus thrombosis in puerperium. (who.int)
Jolly SS, Rai B, Singh N. Cerebral venous sinus thrombosis in puerperium. (who.int)
In most instances, both dural sinus and cortical venous thrombosis occurs simultaneously, with isolation of either being rare due to their effects on one another. (eyewiki.org)
If these arachnoid granulations are disrupted as seen in dural sinus thrombosis, CSF backs up leading to axoplasmic flow stasis with swelling of the optic nerve fiber and optic disc with subsequent venous stasis and extracellular fluid accumulation (i.e., papilledema). (eyewiki.org)
We report the case of a 54-year-old woman in whom thrombosis of the left transverse and sigmoid sinus was diagnosed. (jofem.org)
Of the 10 cases of cerebral venous sinus thrombosis, none were linked to thrombocytopenia (low platelet count). (umn.edu)
Supranuclear oculomotor palsy in cerebral venous sinus thrombosis: a case report. (e-jnc.org)

Of patients evaluated for deep venous thrombosis (DVT) of the lower extremity, only a quarter of them have the disease. (medscape.com)
Haeger K. Problems of acute deep venous thrombosis. (medscape.com)
Systematic lung scans reveal a high frequency of silent pulmonary embolism in patients with proximal deep venous thrombosis. (medscape.com)
Safely ruling out deep venous thrombosis in primary care. (medscape.com)
Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis, and chronic thromboembolic pulmonary hypertension: a scientific statement from the American Heart Association. (medscape.com)
Trends in the incidence of deep vein thrombosis and pulmonary embolism: a 25-year population-based study. (medscape.com)
Useche JN, de Castro AM, Galvis GE, Mantilla RA, Ariza A. Use of US in the evaluation of patients with symptoms of deep venous thrombosis of the lower extremities. (medscape.com)
Deep vein thrombosis of lower extremity: direct intraclot injection of alteplase once daily with systemic anticoagulation--results of pilot study. (medscape.com)
Treatment of symptomatic lower extremity acute deep venous thrombosis: role of mechanical thrombectomy. (medscape.com)
Lower extremity deep venous thrombosis: evaluation with ferumoxytol-enhanced MR imaging and dual-contrast mechanism--preliminary experience. (medscape.com)
The computed tomography venogram shows bilateral deep venous thrombosis (arrows). (medscape.com)
It provides information pertaining to the best practices in preventing deep venous thrombosis and pulmonary embolus. (merlot.org)
Fast Five Quiz: Can You Detect and Appropriately Treat Deep Venous Thrombosis? (medscape.com)
The overall incidence of clinically evident deep venous thrombosis (DVT) was 1.6% without prophylaxis. (sages.org)
Identify acute versus chronic deep vein thrombosis. (iame.com)
In 52 patients with condition after thrombosis of the deep leg veins before discharge from hospital the venous capacity and the venous outflow were measured on the two legs by means of occlusion plethysmography of the veins as well as the percental decrease of the venous pressure during action of the leg muscles by means of phlebodynamometry. (unboundmedicine.com)
Clinical History Symptoms related to protein S deficiency are those associated with deep venous thrombosis (DVT), thrombophlebitis, or pulmonary embolus. (keywen.com)
Deep thrombophlebitis, also known as deep venous thrombosis (DVT), is more serious. (keywen.com)
When thrombophlebitis occurs in a deep vein, a vein that runs deep within muscle tissue, it is called deep venous thrombosis. (keywen.com)
Haeger K. Problems of acute deep venous thrombosis, I: the interpretation of signs and symptoms. (keywen.com)
Venous thrombosis in the leg may occur in the superficial or deep systems of veins. (keywen.com)
ClotCare is a member organization of the Coalition to Prevent Deep Vein Thrombosis. (clotcare.com)
Click here to learn more about the Coalition to Prevent Deep Vein Thrombosis and DVT Awareness Month, which is held each March. (clotcare.com)
These findings were derived from two recent studies published in the British Medical Journal that evaluated the risk of women taking one of these two products and their subsequent risk of developing an idiopathic thromboembolic event, such as a deep vein thrombosis (DVT or a blood clot in the leg) or pulmonary embolism (PE, or a blood clot in the lungs). (clotcare.com)
This 3D medical animation depicting Deep Vein Thrombosis (DVT or Deep Venous Thrombosis) begins by showing a blood clot forming in a lower leg vein. (doereport.com)
The incidence and characterization of deep vein thrombosis following ultrasound-guided foam sclerotherapy in 1000 legs with superficial venous reflux. (ox.ac.uk)
Deep venous segments assessed included common femoral vein, femoral vein, above- and below-knee popliteal veins, gastrocnemius, and tibial veins. (ox.ac.uk)
Pulmonary embolism and deep venous thrombosis / [edited by] Samuel Z. Goldhaber. (who.int)
Objective: Intermittent pneumatic compression (IPC) devices prevent lower-extremity deep venous thrombosis (LEDVT) when used properly, but compliance remains an issue. (utmb.edu)
Deep vein thrombosis is a medical condition in which there is clot formation inside the deep veins of our body. (yesdoct.com)
Certain drugs, insult to deep venous system, recent surgery, decreased or no movement can be the causes that lead to the formation of DVT. (yesdoct.com)
The medical term for blood clots developing in the large veins of the leg or pelvis is deep vein thrombosis (DVT). (cnn.com)
The article summarized the outcome from an actual trial following a postoperative patient death from deep venous thrombosis (DVT)/pulmonary embolism. (aaos.org)
or those with a history of heart attack, stroke, or a prior blood clot in the deep veins of the arms or legs ( deep vein thrombosis ). (medlineplus.gov)
A total of thirty nine patients were admitted for acute coronary syndrome, twenty two patients were admitted for thrombosis-related disorders including deep venous thrombosis and cerebro-vascular accidents and twelve patients were admitted with acute high altitude related illness. (marinemedicalsociety.in)
In addition, polycythemia and increase in blood viscosity result in a demonstrable hypercoagulable state causing Deep Venous Thrombosis (DVT) and stroke. (marinemedicalsociety.in)
[8] Deep Venous Thrombosis (DVT) DVT of calf veins was similarly demonstrated in Pakistani soldiers staying at high altitude for a prolonged period of time. (marinemedicalsociety.in)
The decedent ultimately died from deep venous thrombosis and a pulmonary embolism. (rochestermedicalmalpracticelawyers.net)
We have all heard the warnings about DVT (deep-venous thrombosis) when travelling on long haul flights. (anxietytreat.info)
Subcutaneous unfractionated or low ̶ molecular-weight heparin (LMWH) and thromboguards are often used in the treatment of immobile patients to prevent lower-extremity deep venous thrombosis (DVT) and consequent pulmonary embolism (PE). (medscape.com)

Schaller K, Zillmann U. [The value of occlusion plethysmography and stress venous pressure in functional diagnosis following leg vein thrombosis]. (unboundmedicine.com)
A venous thrombosis is a blood clot that forms within a vein. (keywen.com)
Venous thrombosis is the formation of a thrombus (blood clot) within a vein. (keywen.com)
Venous thrombosis is a known complication in the nephrotic syndrome, with the renal vein being the most frequent site. (keywen.com)
A superficial venous thrombosis is a blood clot in a vein that is close to the surface of the skin. (keywen.com)
As red blood cells flow through the vein, slower moving cells and other blood elements accumulate on the venous valves, creating a stationary blood clot, or thrombus, blocking the blood flow in the vein. (doereport.com)
For patients with ovarian vein thrombosis (OVT), neither the rate of recurrence nor the expected survival are well established. (elsevier.com)
Recurrent thrombosis involved the contralateral ovarian vein, left renal vein, and inferior vena cava. (elsevier.com)
Cortical vein thrombosis presents with motor and sensory deficits, as well as seizure. (emdocs.net)
DVT is defined as venous thrombus forming in a large vein, such as the leg or pelvis, while PE is developed when the thrombus dislodges and spreads through the heart to the pulmonary arteries [ 2 ]. (biomedcentral.com)
Clinical findings of a cortical vein thrombosis depend on the size and extent of the thrombus, location, and nature of collateral supply. (eyewiki.org)
The proposed pathogenesis is as follows: Cortical vein occlusion Increased venous and capillary hydrostatic pressure further blood brain barrier (BBB) disruption Vasogenic edema Intracranial pressure continues to increase Venous/ Capillary rupture and hemorrhage and decreased cerebral perfusion with subsequent ischemia and cytotoxic edema. (eyewiki.org)
Neonatal renal vein thrombosis: role of anticoagulation and thrombolysis-an institutional review. (5minuteconsult.com)
The risk of venous thrombosis, including cerebral vein thrombosis, among women with thrombophilia and oral contraceptive use: a meta-analysis. (bvsalud.org)
2] In the 1950s, Aubaniac used the subclavian vein to insert a central venous catheter (CVC). (medscape.com)
1 Uncommon venous cannulations, such as the catheterization of the great saphenous vein or the popliteal vein (non-central venous lines), have also gained frequency among critically ill patients with COVID-19. (medintensiva.org)
In contrast to hepatic vein thrombosis, formation of a membrane may be an outcome of recurrent thrombosis (Okuda 2001 ). (springeropen.com)

An evaluation of clinical signs in the diagnosis of venous thrombosis. (medscape.com)
SECRET examines the safety of rivaroxaban versus standard-of-care for treatment of symptomatic cerebral venous thrombosis, initiated within 14 days of diagnosis. (clinicaltrials.gov)
During the pilot phase, 50 adult patients within 14 days of symptomatic cerebral venous thrombosis diagnosis will be randomized to receive rivaroxaban 20 mg daily versus standard of care (warfarin or low-molecular weight heparin). (clinicaltrials.gov)
It is used to exclude the diagnosis of venous thrombosis (VTE) because of its excellent negative predictive value (NPV). (hindawi.com)
Headache in early diagnosis of cerebral venous thrombosis: clinical experience in 59 patients. (keywen.com)

Knowledge of the anatomy of the venous system is essential in evaluating patients with cerebral venous thrombosis (CVT), since symptoms associated with the condition are related to the area of thrombosis. (medscape.com)
10 patients again had a venous system without pathologic findings, in 12 patients unchangedly was a complete and in 30 ones in incomplete occlusion. (unboundmedicine.com)
Polycythemia vera should be suspected in patients with elevated hemoglobin or hematocrit levels, splenomegaly, or portal venous thrombosis. (keywen.com)
Because of their fear of recurrent venous thrombosis, patients often become concerned if they develop even minimal exacerbations of symptoms or signs. (keywen.com)
of those 13 patients, nine (23 segments) were thought to have definite thrombosis on contrast-enhanced MRV. (ajronline.org)
Survival, recurrent venous thrombosis rates, and prothrombotic factors were compared to a randomly selected group of 114 female patients with lower extremity venous thrombosis (DVT). (elsevier.com)
During a mean follow-up period of 34.6 ± 44.3 months, three patients suffered three recurrent venous thrombi (event rate: three per 100 patient years of follow-up). (elsevier.com)
Guaranteeing a venous access in critically ill COVID-19 patients may pose a challenge to intensivists who need to strike a balance between optimizing resources and time, minimizing personnel exposure and avoiding equipment contamination/environmental viral spread, while assuring a quick, safe and durable venous line. (medintensiva.org)

Genetic influences such as factor V Leiden play no role of importance in the risk of recurrent venous thrombosis. (keywen.com)
Recurrent venous thrombosis and heparin therapy: an evaluation of the importance of early activated partial thromboplastin times. (keywen.com)

CITATION J Vasc Surg Venous Lymphat Disord . (cun.es)

Important potential causes of headache are pathologic processes involving the dural venous sinuses, the primary outflow pathway of blood from the brain. (ajronline.org)

Thrombosis of the venous channels in the brain is an uncommon cause of cerebral infarction relative to arterial disease, but it is an important consideration because of its potential morbidity. (medscape.com)
If either an arterial or venous thrombosis loses control and starts to travel through the bloodstream, it is called an embolus. (keywen.com)
Dye injection and catheterization is also used to diagnose the presence of arterial and venous thrombosis. (keywen.com)
In 1983, Dr. Graham Hughes described the association between antiphospholipid antibodies and arterial as well as venous thrombosis. (keywen.com)
Thrombosis can occur in blood vessels in any part of the body, and the incidence of venous thrombosis is much higher than that of arterial thrombosis. (medicaltrend.org)

Resistance to activated protein C, for example, has been used as a surrogate for venous thrombosis in women using oral contraceptives. (nih.gov)

Cerebral venous thrombosis (CVT) is often overlooked when intracranial hypertension (ICH) is isolated, hence mimicking idiopathic intracranial hypertension (IIH). (neurology.org)
Central venous thrombosis (CVT) can present with all the classical criteria for idiopathic intracranial hypertension (IIH), including normal brain CT with normal CSF content. (neurology.org)
A thrombosis to the dural sinuses causes a back-up in venous pressure, and may impair this CSF drainage resulting in increased intracranial pressure (e.g. headache, nausea, vomiting, papilledema, and visual problems). (eyewiki.org)

By means of the measuring of the venous pressure still existing obstacles of the outflow of the pelvic and femoral region could be separated from the lower leg and their degree of severity, too, could be quantified. (unboundmedicine.com)
The venous capacity and the venous outflow allowed with sufficient security to delimit the values of the healthy leg from those of the postthrombotic one, whereas a localization of the height and a further quantification of the postthrombotic condition failed. (unboundmedicine.com)
Improved technology of the devices as well as the establishment of venous capacity and venous outflow in one measuring process increase the value of the venous occlusion plethysmography clearly as a non-invasive method which can be carried out by a function-assistant. (unboundmedicine.com)
Nipped in the Budd': hepatic venous outflow obstruction in evolution. (ox.ac.uk)
Budd-Chiari syndrome is defined as a hepatic venous outflow track obstruction of various etiology, which appears at different levels. (springeropen.com)
This syndrome encompasses various hepatic venous outflow blocks, one of which is membranous obstruction of the IVC. (springeropen.com)

A blockage in a central venous catheter. (clevelandclinic.org)

There were no further predisposing factors and mesenteric venous thrombosis was ascribed to oral contraceptives. (keywen.com)
The venous thrombotic risk of oral contraceptives, effects of oestrogen dose and progestogen type: results of the MEGA study. (clotcare.com)
Although many surrogate markers correlate with an outcome, few have been shown to capture the effect of a treatment (for example, oral contraceptives) on the outcome (venous thrombosis). (nih.gov)

Of course, don't be afraid if you have venous thrombosis in the lower extremities. (medicaltrend.org)

Severe venous congestion produces a clinical appearance that can be indistinguishable from the appearance of cellulitis . (medscape.com)
This challenging clinical problem has received new attention since the discovery of certain genetic variants that increase susceptibility to venous thrombosis. (cdc.gov)
What is relevant in clinical practice is the question whether the absence of D-dimers excludes the presence of a venous thrombosis. (keywen.com)
A proper clinical assessment includes a careful evaluation of the patient's signs, symptoms, and risk factors for venous thrombosis. (keywen.com)
Restless legs syndrome appears to be a common overlapping clinical syndrome in people with varicose veins and other chronic venous insufficiency . (mdwiki.org)

Compression has been used for many centuries in the treatment of oedema and other venous and lymphatic disorders of the lower limb. (shockwavetherapymachine.com)

Venous thrombosis may occur with headache and cranial nerve palsies. (keywen.com)

These types of blood clots are called superficial venous thrombosis or phlebitis. (keywen.com)

[ 2 ] and as many as 50% of those with image-documented venous thrombosis lack specific symptoms. (medscape.com)

This section focuses on three common problems of the venous system: varicose veins, venous insufﬁciency, and venous thrombosis. (keywen.com)
[13] Less commonly, but not exceptionally, varicose veins can be due to other causes, such as post-phlebitic obstruction or incontinence, venous and arteriovenous malformations. (mdwiki.org)

Anticardiolipin antibodies and the risk for ischemic stroke and venous thrombosis. (keywen.com)

Several small studies have reported an elevated risk of venous thrombosis (VT) with thrombophilia and oral contraceptive (OCP) use. (bvsalud.org)

Multiple sclerosis and the risk of systemic venous thrombosis: A systematic review. (ox.ac.uk)

Environmental factors that cause vascular injury (e.g., surgery), stasis (e.g., prolonged immobility), or increased coagulability (e.g., hormone use) interact with genetic susceptibility to increase the risk for thrombosis. (cdc.gov)
Increased risk of venous thrombosis in OC users who are carriers of factor V Leiden mutation. (cdc.gov)
The length of anticoagulant therapy depends on the site of thrombosis and on the ongoing presence of risk factors. (medscape.com)
But it can trigger bleeding and that risk outweighs its small benefit in preventing an in-flight venous thrombosis, Dr. Rosendaal says. (keywen.com)
One expert believes the risk of venous thrombosis from air travel is tiny compared with more common causes. (keywen.com)
For people at high risk for thrombosis at home, it is also essential to have an ultrasound examination of the blood vessels every year. (medicaltrend.org)
8] Increasing attention is being paid to preserving central access in children with chronic illness, who often require prolonged or repeated venous access and who are at high risk for venous catheter-related complications that largely derive from elective decisions during catheter insertion and continuing care. (medscape.com)

Venous thrombosis (VT) is a common disorder, according to background information in the article. (keywen.com)
Cerebral venous thrombosis (CVT) is one such disorder as it carries significant morbidity and mortality. (emdocs.net)

This is primarily to rule out the more common secondary pulmonary hypertension related to various left heart conditions or pulmonary venous hypertension-PH classified under WHO group II. (renalandurologynews.com)

The dural sinuses not only act as venous channels, but also contain arachnoid granulations that allow the cerebrospinal fluid (CSF) to drain from the subarachnoid space into the systemic venous system. (eyewiki.org)

Doctors that treat Chronic Venous Embolism Thrombosis Vte in Michigan. (vitadox.com)
[3] Occasionally they result from chronic venous insufficiency . (mdwiki.org)

Anatomy26

Diseases72

Chemicals and Drugs57

Analytical, Diagnostic and Therapeutic Techniques and Equipment61

Phenomena and Processes23

Technology, Industry, Agriculture1

Information Science2

Health Care16

Geographicals2

Inherited prothrombotic risk factors and cerebral venous thrombosis. (1/2331)

Aetiologies and prognosis of Chinese patients with deep vein thrombosis of the lower extremities. (2/2331)

Venous duplex scanning of the leg: range, variability and reproducibility. (3/2331)

G20210A mutation in prothrombin gene and risk of myocardial infarction, stroke, and venous thrombosis in a large cohort of US men. (4/2331)

Low-molecular-weight heparin in outpatient treatment of DVT. (5/2331)

Right atrial bypass grafting for central venous obstruction associated with dialysis access: another treatment option. (6/2331)

Evaluation of lidocaine as an analgesic when added to hypertonic saline for sclerotherapy. (7/2331)

Relief of obstructive pelvic venous symptoms with endoluminal stenting. (8/2331)

Venous Thrombosis

Thrombosis

Thrombophlebitis

Intracranial Thrombosis

Sinus Thrombosis, Intracranial

Phlebography

Iliac Vein

Cerebral Veins

Femoral Vein

Anticoagulants

Pulmonary Embolism

Thrombophilia

Factor V

Coronary Thrombosis

Popliteal Vein

Intracranial Embolism and Thrombosis

Mesenteric Veins

Heparin, Low-Molecular-Weight

Carotid Artery Thrombosis

Sagittal Sinus Thrombosis

Protein S Deficiency

Protein C Deficiency

Prothrombin

Upper Extremity Deep Vein Thrombosis

Vena Cava, Inferior

Postphlebitic Syndrome

Mesenteric Vascular Occlusion

Thromboembolism

Heparin

Ultrasonography, Doppler, Duplex

Activated Protein C Resistance

Postthrombotic Syndrome

Vena Cava Filters

Thrombectomy

Risk Factors

Fibrinolytic Agents

Fibrin Fibrinogen Degradation Products

Venous Thromboembolism

Jugular Veins

Subclavian Vein

Antiphospholipid Syndrome

Blood Coagulation

Catheterization, Peripheral

Stockings, Compression

Axillary Vein

Lateral Sinus Thrombosis

Portal Vein

Protein C

Hemostasis

Thrombolytic Therapy

Warfarin

Renal Veins

Treatment Outcome

Veins

Protein S

Antibodies, Antiphospholipid

Antithrombin III Deficiency

Leg

Retrospective Studies

Lupus Coagulation Inhibitor

Bandages

Fibrinolysis

Budd-Chiari Syndrome

Catheterization, Central Venous

Puerperal Disorders

Follow-Up Studies

Acenocoumarol

Cranial Sinuses

Blood Coagulation Disorders, Inherited

Plethysmography, Impedance

Prospective Studies

Recurrence

Blood Coagulation Tests

Partial Thromboplastin Time

Antibodies, Anticardiolipin

Enoxaparin

Time Factors

Hemorrhage

Case-Control Studies

Fibrinogen