Venous Insufficiency
Varicose Ulcer
Skin breakdown or ulceration caused by VARICOSE VEINS in which there is too much hydrostatic pressure in the superficial venous system of the leg. Venous hypertension leads to increased pressure in the capillary bed, transudation of fluid and proteins into the interstitial space, altering blood flow and supply of nutrients to the skin and subcutaneous tissues, and eventual ulceration.
Venous Pressure
Phlebography
Postphlebitic Syndrome
A condition characterized by a chronically swollen limb, often a leg with stasis dermatitis and ulcerations. This syndrome can appear soon after phlebitis or years later. Postphlebitic syndrome is the result of damaged or incompetent venous valves in the limbs. Distended, tortuous VARICOSE VEINS are usually present. Leg pain may occur after long period of standing.
Chronic Disease
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
Femoral Vein
Adrenal Insufficiency
Ultrasonography, Doppler, Duplex
Gravity Suits
Double-layered inflatable suits which, when inflated, exert pressure on the lower part of the wearer's body. The suits are used to improve or stabilize the circulatory state, i.e., to prevent hypotension, control hemorrhage, and regulate blood pressure. The suits are also used by pilots under positive acceleration.
Leg Ulcer
Azygos Vein
Iliac Vein
Popliteal Vein
Renal Insufficiency
Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
Stockings, Compression
Venous Valves
Exocrine Pancreatic Insufficiency
Jugular Veins
Ultrasonography, Doppler, Color
Ultrasonography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image. This type of ultrasonography is well-suited to identifying the location of high-velocity flow (such as in a stenosis) or of mapping the extent of flow in a certain region.
Placental Insufficiency
Tourniquets
Sclerotherapy
Laser Therapy
Postthrombotic Syndrome
Air
Lower Extremity
Anatomic Variation
Edema
Photoplethysmography
Multiple Sclerosis
An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
Rutin
Periostitis
Inflammation of the periosteum. The condition is generally chronic, and is marked by tenderness and swelling of the bone and an aching pain. Acute periostitis is due to infection, is characterized by diffuse suppuration, severe pain, and constitutional symptoms, and usually results in necrosis. (Dorland, 27th ed)
Ultrasonography, Doppler
Ultrasonography applying the Doppler effect, with frequency-shifted ultrasound reflections produced by moving targets (usually red blood cells) in the bloodstream along the ultrasound axis in direct proportion to the velocity of movement of the targets, to determine both direction and velocity of blood flow. (Stedman, 25th ed)
Severity of Illness Index
Sclerosing Solutions
Chemical agents injected into blood vessels and lymphatic sinuses to shrink or cause localized THROMBOSIS; FIBROSIS, and obliteration of the vessels. This treatment is applied in a number of conditions such as VARICOSE VEINS; HEMORRHOIDS; GASTRIC VARICES; ESOPHAGEAL VARICES; PEPTIC ULCER HEMORRHAGE.
Onychomycosis
Treatment Outcome
Vascular Malformations
A spectrum of congenital, inherited, or acquired abnormalities in BLOOD VESSELS that can adversely affect the normal blood flow in ARTERIES or VEINS. Most are congenital defects such as abnormal communications between blood vessels (fistula), shunting of arterial blood directly into veins bypassing the CAPILLARIES (arteriovenous malformations), formation of large dilated blood blood-filled vessels (cavernous angioma), and swollen capillaries (capillary telangiectases). In rare cases, vascular malformations can result from trauma or diseases.
Constriction, Pathologic
Nursing Assessment
Subcutaneous Tissue
Multiple Sclerosis, Chronic Progressive
A form of multiple sclerosis characterized by a progressive deterioration in neurologic function which is in contrast to the more typical relapsing remitting form. If the clinical course is free of distinct remissions, it is referred to as primary progressive multiple sclerosis. When the progressive decline is punctuated by acute exacerbations, it is referred to as progressive relapsing multiple sclerosis. The term secondary progressive multiple sclerosis is used when relapsing remitting multiple sclerosis evolves into the chronic progressive form. (From Ann Neurol 1994;36 Suppl:S73-S79; Adams et al., Principles of Neurology, 6th ed, pp903-914)
Multiple Sclerosis, Relapsing-Remitting
The most common clinical variant of MULTIPLE SCLEROSIS, characterized by recurrent acute exacerbations of neurologic dysfunction followed by partial or complete recovery. Common clinical manifestations include loss of visual (see OPTIC NEURITIS), motor, sensory, or bladder function. Acute episodes of demyelination may occur at any site in the central nervous system, and commonly involve the optic nerves, spinal cord, brain stem, and cerebellum. (Adams et al., Principles of Neurology, 6th ed, pp903-914)
Vascular Diseases
Foot
Catheterization, Peripheral
Endoscopy
Procedures of applying ENDOSCOPES for disease diagnosis and treatment. Endoscopy involves passing an optical instrument through a small incision in the skin i.e., percutaneous; or through a natural orifice and along natural body pathways such as the digestive tract; and/or through an incision in the wall of a tubular structure or organ, i.e. transluminal, to examine or perform surgery on the interior parts of the body.
Prospective Studies
Primary Ovarian Insufficiency
Cessation of ovarian function after MENARCHE but before the age of 40, without or with OVARIAN FOLLICLE depletion. It is characterized by the presence of OLIGOMENORRHEA or AMENORRHEA, elevated GONADOTROPINS, and low ESTRADIOL levels. It is a state of female HYPERGONADOTROPIC HYPOGONADISM. Etiologies include genetic defects, autoimmune processes, chemotherapy, radiation, and infections.
Pressure
Skin
Hepatic Insufficiency
Follow-Up Studies
Hemodynamics
Retrospective Studies
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Blood Flow Velocity
Addison Disease
An adrenal disease characterized by the progressive destruction of the ADRENAL CORTEX, resulting in insufficient production of ALDOSTERONE and HYDROCORTISONE. Clinical symptoms include ANOREXIA; NAUSEA; WEIGHT LOSS; MUSCLE WEAKNESS; and HYPERPIGMENTATION of the SKIN due to increase in circulating levels of ACTH precursor hormone which stimulates MELANOCYTES.
Risk Factors
Case-Control Studies
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Ultrasonography, Doppler, Transcranial
A non-invasive technique using ultrasound for the measurement of cerebrovascular hemodynamics, particularly cerebral blood flow velocity and cerebral collateral flow. With a high-intensity, low-frequency pulse probe, the intracranial arteries may be studied transtemporally, transorbitally, or from below the foramen magnum.
Respiratory Insufficiency
Postoperative Complications
Aortic Valve Insufficiency
Mid-term results of endoscopic perforator vein interruption for chronic venous insufficiency: lessons learned from the North American subfascial endoscopic perforator surgery registry. The North American Study Group. (1/535)
PURPOSE: The safety, feasibility, and early efficacy of subfascial endoscopic perforator surgery (SEPS) for the treatment of chronic venous insufficiency were established in a preliminary report. The long-term clinical outcome and the late complications after SEPS are as yet undetermined. METHODS: The North American Subfascial Endoscopic Perforator Surgery registry collected information on 148 SEPS procedures that were performed in 17 centers in the United States and Canada between August 1, 1993, and February 15, 1996. The data analysis in this study focused on mid-term outcome in 146 patients. RESULTS: One hundred forty-six patients (79 men and 67 women; mean age, 56 years; range, 27 to 87 years) underwent SEPS. One hundred and one patients (69%) had active ulcers (class 6), and 21 (14%) had healed ulcers (class 5). One hundred and three patients (71%) underwent concomitant venous procedures (stripping, 70; high ligation, 17; varicosity avulsion alone, 16). There were no deaths or pulmonary embolisms. One deep venous thrombosis occurred at 2 months. The follow-up periods averaged 24 months (range, 1 to 53 months). Cumulative ulcer healing at 1 year was 88% (median time to healing, 54 days). Concomitant ablation of superficial reflux and lack of deep venous obstruction predicted ulcer healing (P <.05). Clinical score improved from 8.93 to 3.98 at the last follow-up (P <. 0001). Cumulative ulcer recurrence at 1 year was 16% and at 2 years was 28% (standard error, < 10%). Post-thrombotic limbs had a higher 2-year cumulative recurrence rate (46%) than did those limbs with primary valvular incompetence (20%; P <.05). Twenty-eight of the 122 patients (23%) who had class 5 or class 6 ulcers before surgery had an active ulcer at the last follow-up examination. CONCLUSIONS: The interruption of perforators with ablation of superficial reflux is effective in decreasing the symptoms of chronic venous insufficiency and rapidly healing ulcers. Recurrence or new ulcer development, however, is still significant, particularly in post-thrombotic limbs. The reevaluation of the indications for SEPS is warranted because operations in patients without previous deep vein thrombosis are successful but operations in those patients with deep vein thrombosis are less successful. Operations on patients with deep vein occlusion have poor outcomes. (+info)Bypass graft of an occluded inferior vena cava: report of a case with patency at five years. (2/535)
Venous reconstructive surgery for chronic occlusive disease has evolved slower than its arterial counterpart. Factors intrinsic to the venous system that have been implicated in discouraging experimental and clinical results include enhanced graft thrombogenicity, low velocity of blood flow, and wall collapsibility. 1,2 We present a case of a 24-year-old man with symptomatic occlusion of the inferior vena cava, treated with a prosthetic bypass graft to the supra diaphragmatic cava. The graft was patent 5 years later, and the patient remained asymptomatic. (+info)Endothelial activation response to oral micronised flavonoid therapy in patients with chronic venous disease--a prospective study. (3/535)
BACKGROUND: Endothelial activation is important in the pathogenesis of skin changes due to chronic venous disease (CVD). Purified micronised flavonoid fraction has been used for symptomatic treatment of CVD for a considerable period of time. The exact mode of action of these compounds remains unknown. AIM: To study the effects of micronised purified flavonoidic fraction (Daflon 500 mg, Servier, France) treatment on plasma markers of endothelial activation. MATERIALS AND METHODS: Twenty patients with chronic venous disease were treated for 60 days with DAFLON 500 mg twice daily. Duplex ultrasonography and PPG was used to assess the venous disease. Blood was collected from a foot vein immediately before starting treatment and within 1 week of stopping treatment. Plasma markers of endothelial activation were measured using commercial ELISA kits. RESULTS: Reduction in the level of ICAM-1, 32% (141 ng/ml: 73 ng/ml) and VCAM 29% (1292 ng/ml: 717 ng/ml) was seen. Reduction in plasma lactoferrin (36% decrease, 760 ng/ml: 560 ng/ml) and VW factor occurred in the C4 group only. CONCLUSIONS: Micronised purified flavonoidic fraction treatment for 60 days seems to decrease the levels of some plasma markers of endothelial activation. This could ameliorate the dermatological effects of (CVD). This could also explain some of the pharmacological actions of these compounds. Our study demonstrates the feasibility of using soluble endothelial adhesion molecules as markers for treatment. (+info)Movement-related variation in forces under compression stockings. (4/535)
OBJECTIVES: Compression therapy is widely used in the treatment of venous leg ulcers, but the efficacy of this treatment is variable. Assessment of variation in compression forces associated with movement may help to elucidate the mechanism of action of compression therapy. The aim of this study was to develop and apply a system to investigate forces under compression stockings during movement. METHOD: Three sensors were placed on the medial aspect of the left leg on six healthy volunteers to monitor forces under class 2 (Continental European classification) compression stockings. Data were recorded during dorsiflexion and plantar flexion of the left foot and also during short periods of walking. RESULTS: Changes in pressure were observed, associated with dorsiflexion and plantar flexion of the foot. These changes were dependent on sensor position. Changes in pressure during walking were also position-dependent and of variable duration. CONCLUSIONS: The system enables forces associated with compression therapy to be examined during movement and may thus be of value in further understanding its mechanism of action. Foot movement can be associated with clear changes in pressure under compression stockings and rapid changes in pressure may occur during walking. (+info)Risk factors for erysipelas of the leg (cellulitis): case-control study. (5/535)
OBJECTIVE: To assess risk factors for erysipelas of the leg (cellulitis). DESIGN: Case-control study. SETTING: 7 hospital centres in France. SUBJECTS: 167 patients admitted to hospital for erysipelas of the leg and 294 controls. RESULTS: In multivariate analysis, a disruption of the cutaneous barrier (leg ulcer, wound, fissurated toe-web intertrigo, pressure ulcer, or leg dermatosis) (odds ratio 23.8, 95% confidence interval 10.7 to 52.5), lymphoedema (71.2, 5.6 to 908), venous insufficiency (2.9, 1.0 to 8.7), leg oedema (2.5, 1.2 to 5.1) and being overweight (2.0, 1.1 to 3.7) were independently associated with erysipelas of the leg. No association was observed with diabetes, alcohol, or smoking. Population attributable risk for toe-web intertrigo was 61%. CONCLUSION: This first case-control study highlights the major role of local risk factors (mainly lymphoedema and site of entry) in erysipelas of the leg. From a public health perspective, detecting and treating toe-web intertrigo should be evaluated in the secondary prevention of erysipelas of the leg. (+info)Leukocyte activation in patients with venous insufficiency. (6/535)
PURPOSE: Cell activation may play an important role in the production of venous insufficiency, just as leukocytes participate in the cause of venous ulcer. If activated, monocytes observed on venous endothelium can migrate into the venous wall and produce toxic metabolites and free oxygen radicals that may participate in valve destruction and venous wall weakening. At present, it remains uncertain to what degree leukocytes are actually activated in patients. This study was designed to explore the level of activation and to examine whether patient plasma contains an activator that leads to leukocyte activation of unstimulated naive leukocytes from volunteers without venous insufficiency disease. METHODS: Twenty-one patients (4 men, 17 women), who ranged in age from 34 to 69 years (mean age, 53.2 years), with chronic venous disease were compared with 16 healthy control volunteers (4 men, 12 women), who ranged in age from 18 to 65 years (mean age, 48.4 years). All the patients underwent evaluation with Doppler ultrasound scanning and were classified with the CEAP score.1 Nearly all the patients who smoked or were hypertensive were excluded. The blood types (ABO and Rh) of the controls were matched to the study group. Isolates of patient whole blood, plasma, or leukocytes were incubated with isolates of control whole blood, plasma, or leukocytes to separate actual activation from spontaneously observed activation. The granulocyte activation was measured with nitroblue tetrazolium (NBT) reduction and quantitation of granulocyte pseudopod formation. Hydrogen peroxide production in patient plasma was measured with a recently developed electrode method. RESULTS: Leukocytes from healthy blood and patient plasma had significantly higher NBT-positive granulocyte counts than either patient blood, healthy blood, or patient blood incubated in healthy plasma. In a comparison of patient groups across the CEAP classes, the NBT-positive granulocyte counts were significantly greater in classes 4, 5, and 6 than in classes 2 and 3 (P <.001). Pseudopod formation was significantly greater in mixtures of granulocytes in healthy blood and patient plasma than in all other groups. There was no difference in the level of pseudopod formation in control leukocytes incubated with patient plasma in patients across the CEAP spectrum. The patient plasma produced significantly higher hydrogen peroxide values than did the controls. CONCLUSION: These results suggest that patient plasma may contain an activating factor for granulocytes. The finding that activated neutrophils were fewer in number in patient whole blood than in healthy blood incubated in patient plasma could suggest that activated neutrophils in patients with chronic venous insufficiency might be trapped in the peripheral circulation. It is unknown what factors in the plasma might induce activation of naive neutrophils, but such activators could possibly be important in the pathogenesis of primary venous dysfunction and the development of chronic venous insufficiency. (+info)Prevalence of varicose veins and chronic venous insufficiency in men and women in the general population: Edinburgh Vein Study. (7/535)
STUDY OBJECTIVE: To determine the prevalence of varicose veins and chronic venous insufficiency (CVI) in the general population. DESIGN: Cross sectional survey. SETTING: City of Edinburgh. PARTICIPANTS: Men and women aged 18-64 years selected randomly from age-sex registers of 12 general practices. MAIN RESULTS: In 1566 subjects examined, the age adjusted prevalence of trunk varices was 40% in men and 32% in women (p < or = 0.01). This sex difference was mostly a result of higher prevalence of mild trunk varices in men. More than 80% of all subjects had mild hyphenweb and reticular varices. The age adjusted prevalence of CVI was 9% in men and 7% in women (p < or = 0.05). The prevalence of all categories of varices and of CVI increased with age (p < or = 0.001). No relation was found with social class. CONCLUSIONS: Approximately one third of men and women aged 18-64 years had trunk varices. In contrast with the findings in most previous studies, mainly conducted in the 1960s and 1970s, chronic venous insufficiency and mild varicose veins were more common in men than women. No evidence of bias in the study was found to account for this sex difference. Changes in lifestyle or other factors might be contributing to an alteration in the epidemiology of venous disease. (+info)Prophylactic inferior vena cava filters in trauma patients at high risk: follow-up examination and risk/benefit assessment. (8/535)
PURPOSE: The efficacy of prophylactic inferior vena cava filters in selected trauma patients at high risk has come into question in relation to risk/benefit assessment. To evaluate the usefulness of prophylactic inferior vena cava filters, we reviewed our experience and overall complication rate. METHODS: From February 1991 to April 1998, the trauma registry identified 7333 admissions. One hundred eighty-seven prophylactic inferior vena cava filters were inserted. After the exclusion of 27 trauma-related deaths (none caused by thromboembolism), 160 patients were eligible for the study. The eligible patients were contacted and asked to complete a survey and return for a follow-up examination to include physical examination, Doppler scan study, vena cava duplex scanning, and fluoroscopic examination. The patients' hospital charts were reviewed in detail. The indications for prophylactic inferior vena cava filter insertion included prolonged immobilization with multiple injuries, closed head injury, pelvic fracture, spine fracture, multiple long bone fracture, and attending discretion. RESULTS: Of the 160 eligible patients, 127 were men, the mean age was 40.3 years, and the mean injury severity score was 26.1. The mean day of insertion was hospital day 6. Seventy-five patients (47%) returned for evaluation, with a mean follow-up period of 19.4 months after implantation (range, 7 to 60 months). On survey, patients had leg swelling (n = 27), lower extremity numbness (n = 14), shortness of breath (n = 9), chest pain (n = 7), and skin changes (n = 4). All the survey symptoms appeared to be attributable to patient injuries and not related to prophylactic inferior vena cava filter. Physical examination results revealed edema (n = 12) and skin changes (n = 2). Ten Doppler scan studies had results that were suggestive of venous insufficiency, nine of which had histories of deep vein thrombosis. With duplex scanning, 93% (70 of 75) of the vena cavas were visualized, and all were patent. Only 52% (39 of 75) of the prophylactic inferior vena cava filters were visualized with duplex scanning. All the prophylactic inferior vena cava filters were visualized with fluoroscopy, with no evidence of filter migration. Of the total 187 patients, 24 (12.8%) had deep vein thrombosis develop after prophylactic inferior vena cava filter insertion, including 10 of 75 (13.3%) in the follow-up group, and one patient had a nonfatal pulmonary embolism despite filter placement. Filter insertion complications occurred in 1.6% (three of 187) of patients and included one groin hematoma, one arteriovenous fistula, and one misplacement in the common iliac vein. CONCLUSION: This study's results show that prophylactic inferior vena cava filters can be placed safely with low morbidity and no attributable long-term disabilities. In this patient population with a high risk of pulmonary embolism, prophylactic inferior vena cava filters offered a 99.5% protection rate, with only one of 187 patients having a nonfatal pulmonary embolism. (+info)
Chronic Cerebrospinal Venous Insufficiency (CCSVI) and Multiple Sclerosis (MS): A Critical Review | BenthamScience
Chronic Cerebrospinal Venous Insufficiency (CCSVI) - Page 130 - This Is MS Multiple Sclerosis Community: Knowledge & Support
Chronic Cerebrospinal Venous Insufficiency (CCSVI) - Page 3 - This Is MS Multiple Sclerosis Community: Knowledge & Support
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Help with Edema (swollen ankle/calf)
Help with Edema (swollen ankle/calf)
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Cerebrospinal venous35
- Zaniewski M, Simka M. Biophysics of venous return from the brain from the perspective of the pathophysiology of chronic cerebrospinal venous insufficiency. (medscape.com)
- Extra- and transcranial echo colour Doppler in the diagnosis of chronic cerebrospinal venous insufficiency. (medscape.com)
- Zamboni P, Galeotti R, Menegatti E et al (2009) Chronic cerebrospinal venous insufficiency in patients with multiple sclerosis. (springer.com)
- Zamboni P, Menegatti E, Weinstock-Guttman B et al (2009) The severity of chronic cerebrospinal venous insufficiency in patients with multiple sclerosis is related to altered cerebrospinal fluid dynamics. (springer.com)
- There appears to be no link between chronic cerebrospinal venous insufficiency and multiple sclerosis (MS), in the findings of a new research published in CMAJ (Canadian Medical Association Journal). (medindia.net)
- Chronic cerebrospinal venous insufficiency or CCSVI is a condition in which the blood flow in the veins that drain the central nervous system is obstructed. (medindia.net)
- The present research found no link between CCSVI and MS. 'We detected no link between chronic cerebrospinal venous insufficiency and multiple sclerosis,' reported lead author of the study Dr. Fiona Costello from the department of Clinical Neurosciences and Surgery, University of Calgary, Calgary, Alberta. (medindia.net)
- We also identified several methodologic concerns that challenge the validity of the criteria used to define chronic cerebrospinal venous insufficiency, and in turn we dispute the authenticity of this diagnosis,' she said. (medindia.net)
- HOUSTON - Results of a study using several imaging methods showed that CCSVI (chronic cerebrospinal venous insufficiency) occurs at a low rate in both people with multiple sclerosis (MS) and non-MS volunteers, contrary to some previous studies. (healthcanal.com)
- Doctor Haacke has developed a protocol for detecting the condition cerebrospinal venous insufficiency or CCSVI. (patientslikeme.com)
- this provides a picture of chronic cerebrospinal venous insufficiency (CCSVI) with four different patterns of distribution of stenosis and substitute circle. (bmj.com)
- Posture and the mechanic movement of respiration play a fundamental role in ensuring the correct cerebrospinal venous outflow. (bmj.com)
- 2 In addition, it has been proved that training is mandatory to improve reproducibility of chronic cerebrospinal venous insufficiency (CCSVI) screening. (ajnr.org)
- The aim of this open-label study was to assess extracranial Doppler criteria of chronic cerebrospinal venous insufficiency in multiple sclerosis patients. (nih.gov)
- We found at least two of four extracranial criteria in 63 patients (90.0%), confirming that multiple sclerosis is stronghly associated with chronic cerebrospinal venous insufficiency. (nih.gov)
- Multiple sclerosis is highly correlated with chronic cerebrospinal venous insufficiency. (nih.gov)
- In 2009, Dr. Paolo Zamboni postulated that chronic cerebrospinal venous insufficiency is a cause of MS, an inflammatory disease of the central nervous system that affects people in northern climates in particular. (medicalxpress.com)
- Several recent studies have shown an association between ultrasound-diagnosed chronic cerebrospinal venous insufficiency and MS but results vary widely. (medicalxpress.com)
- Using ultrasound technology and magnetic resonance venography, researchers undertook a study to explore the validity of the theory that chronic cerebrospinal venous insufficiency and MS are linked. (medicalxpress.com)
- A high percentage of patients (58%) and controls (63%) met one or more proposed ultrasound criteria that would help diagnose chronic cerebrospinal venous insufficiency although there were no differences seen between groups. (medicalxpress.com)
- We detected no link between chronic cerebrospinal venous insufficiency and multiple sclerosis ," writes Dr. Fiona Costello, departments of Clinical Neurosciences and Surgery, University of Calgary, Calgary, Alberta, with coauthors. (medicalxpress.com)
- They cite concerns over the diagnosis of chronic cerebrospinal venous insufficiency. (medicalxpress.com)
- A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis. (thisisms.com)
- This thread is to keep track of the research related to the CCSVI -Chronic CerebroSpinal Venous Insufficiency-- in one accessible place. (thisisms.com)
- We would like to comment on the recently published study entitled "Mystery of Chronic Cerebrospinal Venous Insufficiency: Identical Venographic and Ultrasound Findings in Patients with MS and Controls" by McAuliffe and Kermode. (ajnr.org)
- Data were missing about the training of actual investigators concerning chronic cerebrospinal venous insufficiency (CCSVI), keeping in mind that the patients examined were their initial 30 cases. (ajnr.org)
- balloon angioplasty for chronic cerebrospinal venous insufficiency in M.E. (meassociation.org.uk)
- The National Institute for Health and Clinical (NICE) has not issued any guidance on the use of balloon angioplasty for chronic cerebrospinal venous insufficiency for patients with myalgic encephalomyelitis and there are no plans for it to develop guidance on this topic. (meassociation.org.uk)
- The Ontario Health Technology Advisory Committee has undertaken a preliminary evidence review of the safety and effectiveness of endovascular treatments for the proposed condition known as chronic cerebrospinal venous insufficiency in patients with multiple sclerosis and is unable to make any recommendation at this time due to the paucity of available evidence. (hqontario.ca)
- Evidence concerning the prevalence of chronic cerebrospinal venous insufficiency available up to July 2011 was reviewed by the Ontario Health Technology Advisory Committee, and no changes to the May 2010 recommendations were deemed necessary. (hqontario.ca)
- A recent theory proposed that an abnormality in the vein that drains blood from the brain and spinal cord may be associated with MS and that treating this problem might hold promise as a treatment for MS. The abnormality is known as chronic cerebrospinal venous insufficiency. (hqontario.ca)
- This article discusses the biophysical aspects of venous outflow from the brain in healthy individuals and in patients with chronic cerebrospinal venous insufficiency. (eurekaselect.com)
- This may mean that chronic cerebrospinal venous insufficiency may cause the destruction of the delicate nervous tissue of the central nervous system. (eurekaselect.com)
- Maciej Zaniewski and Marian Simka, "Biophysics of Venous Return from the Brain from the Perspective of the Pathophysiology of Chronic Cerebrospinal Venous Insufficiency", Reviews on Recent Clinical Trials (2012) 7: 88. (eurekaselect.com)
- Objective Chronic cerebrospinal venous insufficiency (CCSVI) has been extremely variable, associated with multiple sclerosis in colour-Doppler sonographic studies. (bmj.com)
Ulcers45
- Renner R, Gebhardt C, Simon JC, Seikowski K. Changes in quality of life for patients with chronic venous insufficiency, present or healed leg ulcers. (medscape.com)
- How does venous insufficiency cause nonhealing ulcers? (medscape.com)
- Nonhealing ulcers on the medial part of the ankle are most likely due to underlying venous stasis. (medscape.com)
- See Superficial Venous Insufficiency: Varicose Veins and Venous Ulcers , a Critical Images slideshow, to help identify the common risk factors and features of this condition and its management options. (medscape.com)
- Leg vein malfunction (venous insufficiency) affects 2-5% of Americans, and approximately half a million Americans have stasis ulcers. (reference.com)
- While chronic venous insufficiency is not a serious health threat, it can be painful and disabling if left untreated, causing symptoms such as varicose veins, leg ulcers, swelling, and skin changes. (cooperhealth.org)
- Signs and symptoms of CVI in the leg include the following: Varicose veins Itching (pruritus) Hyperpigmentation Phlebetic lymphedema Chronic swelling of the legs and ankles Venous ulceration CVI in the leg may cause the following: Venous stasis Ulcers. (wikipedia.org)
- If chronic venous insufficiency is left untreated, pain, swelling, and leg ulcers may result. (baycare.org)
- They also can help venous skin ulcers heal. (peacehealth.org)
- Venous insufficiency often occurs in the legs, and is associated with EDEMA and sometimes with VENOUS STASIS ULCERS at the ankle. (harvard.edu)
- Pathophysiology of Chronic Venous Disease and Venous Ulcers. (harvard.edu)
- Venous ulcers in chronic venous insufficiency: King Khalid University Hospital experience. (biomedsearch.com)
- BACKGROUND: The purpose of this study was to identify the anatomical location of the venous disease in C.V.I. patients presented with venous ulcers in addition to discussing the management. (biomedsearch.com)
- RESULTS: Forty eight (48) patients (57 limbs) had Stage III with venous ulcers. (biomedsearch.com)
- Venous ulcers, also referred to as stasis, insufficiency or varicose ulcers, are the result of malfunctioning venous valves causing pressure in the veins to increase . (woundsource.com)
- Venous ulcers will present with shallow but large wounds with irregular margins that typically develop on the lower leg or ankle. (woundsource.com)
- Any condition that causes blood to pool in the veins of the leg is a potential cause of venous ulcers, including varicose veins , deep vein thrombosis , or heart failure . (woundsource.com)
- Most venous ulcers are caused by venous valves that do not properly prevent the backflow of blood, or venous reflux, from deep veins back to the superficial veins located between the skin and muscles. (woundsource.com)
- One of the most typical complications associated with venous insufficiency ulcers is infection of the affected tissue. (woundsource.com)
- In directly treating venous ulcers, the primary goals are keeping the ulcer site infection-free during the healing process and alleviating edema of the site. (woundsource.com)
- In extreme cases, surgical skin grafts can be used in order for abnormally large or painful venous ulcers to properly heal. (woundsource.com)
- In addition to treating the superficial wound and edema, the secondary goal in treating venous ulcers is to alleviate the underlying condition. (woundsource.com)
- Chronic venous insufficiency is a common medical problem, with symptoms ranging from mildly unsightly veins to recurrent skin infections and ulcers that require hospitalization. (nutritionmd.org)
- CVI is defined as morphological and functional abnormalities of the venous system manifested by varicose veins (structural changes in the vein wall), venous leg ulcers, oedema, or skin changes. (hindawi.com)
- Chronic leg ulcers are a serious complication of chronic venous insufficiency. (lymphedemapeople.com)
- People with long-term, untreated venous insufficiency sometimes develop open sores in the skin called venous ulcers. (nyp.org)
- Venous ulcers usually appear just above the ankle on the inside of the leg. (nyp.org)
- If venous insufficiency is not treated, venous ulcers may develop on the lower legs. (nyp.org)
- Doctors treat venous ulcers by working to prevent infection and promote healing of the wound. (nyp.org)
- Many novel treatments, outlined below, are now available to help heal venous ulcers. (nyp.org)
- In addition, compression stockings can help prevent venous ulcers from forming or can help accelerate the healing of an existing ulcer. (nyp.org)
- The ulcers appear to be caused by the prolonged elevation of venous pressure in the leg and the resultant edema. (ahajournals.org)
- The use of this device in the treatment of ulcers due to chronic venous insufficiency is also described. (ahajournals.org)
- About 1% of the total cost of inpatient medical care in Germany is spent on the treatment of venous leg ulcers ( 7 ). (aerzteblatt.de)
- It does seem, however, that the incidence and prevalence of venous leg ulcers are both lower than they were reported to be in the 1970s. (aerzteblatt.de)
- No reliable figures are available for the prevalence or incidence of stage IV PAOD or of leg ulcers of mixed arterial and venous pathogenesis. (aerzteblatt.de)
- Although no precise epidemiological data are available on the frequency of recurrence of chronic wounds, individual studies have shown that both diabetic foot ulcers and venous insufficiency ulcers tend to recur, particularly when peripheral arterial hypoperfusion is also present ( 12 ). (aerzteblatt.de)
- Deep system valve malfunction could be due to prior clots, superficial problems could lead to varicose veins and perforator malfunction could lead to venous ulcers. (healthtap.com)
- Otherwise, CVI can lead to varicose veins [link to new Varicose Veins page] and venous ulcers (skin sores) on the lower legs. (henryford.com)
- Ulcers may develop on the inside of the ankle in people with chronic venous insufficiency. (merckmanuals.com)
- Venous stasis dermatitis consists of reddish brown hyperpigmentation, induration, venous ectasia, lipodermatosclerosis (fibrosing subcutaneous panniculitis), and venous stasis ulcers. (merckmanuals.com)
- Venous ulcers (open sores) can occur when the veins in your legs do not push blood back up to your heart as well as they should. (adam.com)
- Pycnogenol, a standardized extract of French maritime pine bark, has been shown to promote healing of venous ulcers and reduce leg edema and the risk of blood clots during long flights. (lifeextension.com)
- The benefits of horse chestnut for venous health can possibly improve the flow of blood in Chronic Venous Insufficiency (CVI), a disorder characterised by itchiness, varicose veins, swelling, increased leg pigmentation, and ulcers. (tasmanhealth.co.nz)
- This results in tissue breakdown and venous skin ulcers. (medicalrecords.com)
Veins80
- Casian D, Gutsu E, Culiuc V. Surgical treatment of severe chronic venous insufficiency caused by pulsatile varicose veins in a patient with tricuspid regurgitation. (medscape.com)
- Venous insufficiency is a condition in which the veins have problems sending blood from the legs back to the heart. (medlineplus.gov)
- Venous insufficiency is a condition in which the veins fail to return blood efficiently to the heart. (medlineplus.gov)
- In venous insufficiency states, venous blood escapes from its normal antegrade path of flow and refluxes backward down the veins into an already congested leg. (medscape.com)
- Arterial inflow fills the leg veins slowly, and the only source of venous pressure is the hydrostatic pressure of a column of blood as high as the nearest competent valve. (medscape.com)
- In venous insufficiency, after prolonged standing, the veins are completely filled, and all the venous valves float open. (medscape.com)
- First, bicuspid valves in the veins prevent backflow and venous pooling. (medscape.com)
- Venous insufficiency means the veins have trouble with blood flow. (reference.com)
- Chronic venous insufficiency occurs when your leg veins don't allow blood to flow back up to your heart. (reference.com)
- Venous insufficiency is a condition with the body's veins ability to function properly. (reference.com)
- Varicose veins, a condition closely related to venous insufficiency, occur when veins near the surface of the skin are damaged. (epnet.com)
- In the last years, it has been suggested that an abnormal venous drainage due to stenosis or malformation of the internal jugular and/or azygous veins may play a major pathogenetic role in MS. This abnormality called chronic cerebro-spinal venous insufficiency (CCSVI) could result in increased permeability of blood brain barrier, local iron deposition and secondary multifocal inflammation. (springer.com)
- By artificially activating lower leg muscles, venous blood may be effectively ejected from the muscle and adjacent veins. (embs.org)
- A catheter delivers an electrode within a vein for a minimally invasive treatment of varicose veins and venous insufficiency using RF energy. (google.de)
- Venous insufficiency occurs when the veins in the legs do not return blood to the heart and upper body normally. (cardiosmart.org)
- Venous insufficiency means that the valves in the veins have become damaged, allowing blood to flow backward and pool in the leg veins. (cardiosmart.org)
- Pathophysiology of varicose veins and chronic venous insufficiency. (springer.com)
- Chronic venous insufficiency (CVI) results when the veins in the legs no longer pump blood back to the heart effectively. (ucdavis.edu)
- Blood clots can lead to CVI when they block venous blood-flow or when the clot damages the valves in the veins. (ucdavis.edu)
- Chronic venous insufficiency is caused when leg veins cannot pump enough blood back into the heart. (eurekalert.org)
- Venous insufficiency can refer to: Varicose veins Chronic venous insufficiency Venous stasis This disambiguation page lists articles associated with the title Venous insufficiency. (wikipedia.org)
- Common leg vein health issues stemming from chronic venous insufficiency (CVI) include varicose veins, spider veins and deep vein thrombosis. (health24.com)
- Chronic venous insufficiency (CVI) is a medical condition in which blood pools in the veins, straining the walls of the vein. (wikipedia.org)
- It is sometimes called chronic peripheral venous insufficiency and should not be confused with post-thrombotic syndrome in which the deep veins have been damaged by previous deep vein thrombosis. (wikipedia.org)
- Anxiety Depression Inflammation Cellulitis The most common cause of chronic venous insufficiency is reflux of the venous valves of superficial veins. (wikipedia.org)
- According to Widmer classification diagnosis of chronic venous insufficiency is clearly differentiated from varicose veins. (wikipedia.org)
- Chronic venous insufficiency occurs when the leg veins do not allow blood to travel back to the heart. (baycare.org)
- Venous insufficiency is a problem with the flow of blood from the veins of the legs back to the heart. (peacehealth.org)
- In venous insufficiency, the valves in the veins of the leg don't work right. (peacehealth.org)
- Venous insufficiency is sometimes caused by deep vein thrombosis and high blood pressure inside leg veins. (peacehealth.org)
- This venous insufficiency can cause varicose veins, which are enlarged blood vessels - often in the calves, thighs and feet - that may look swollen, bulging or ropey. (sciton.com)
- Professor Paolo Zamboni, a vascular surgeon from the University of Ferrara, Italy, found a link between pressure in the veins, iron deposition, and ulceration in venous disease of the legs. (medindia.net)
- His research showed that venous abnormalities are linked with multiple sclerosis because the veins responsible for blood flow out of the brain and spinal cord of patients with multiple sclerosis were abnormally narrowed or even blocked in some places. (medindia.net)
- Color-Doppler interrogation differentiates partial thrombosis from occlusion, distinguishes deep from superficial venous reflux at saphenofemoral and saphenopopliteal junctions, identifies incompetent perforating veins, and demonstrates recanalization of chronically thrombosed venous segment and collateralization. (clinicaladvisor.com)
- Chronic venous insufficiency is a problem with how your veins are working. (memorialhospitaljax.com)
- Chronic venous insufficiency is caused by higher than normal pressure in the veins and damage to the valves that keep blood flowing toward the heart. (memorialhospitaljax.com)
- The venous system operates at relatively low blood pressure, relying on the contraction and expansion of skeletal muscles to propel blood past the one-way valves in the veins on its way back to the heart. (woundsource.com)
- Venous insufficiency is described as abnormal blood flow through veins that can cause local damage, damage to affected legs, or death . (thefreedictionary.com)
- Cancer obstructing veins in the pelvis area can cause superficial venous insufficiency. (thefreedictionary.com)
- Deep venous insufficiency is commonly caused by thrombophlebitis , causing obstruction of valves that regulate blood flow in veins. (thefreedictionary.com)
- This valvular incompetence will cause an increase in the presence within veins (venous hypertension ). (thefreedictionary.com)
- The most common form of CVI is primary varicose veins due to the insufficiency of the saphenous system. (unboundmedicine.com)
- The venous network in the lower extremities is divided into three systems: superficial, deep, and perforating veins. (unboundmedicine.com)
- Femoro-popliteal veins are evaluated with color and PW Doppler for valvular insufficiency with reflux by performing Valsalva maneuver and calf compression. (unboundmedicine.com)
- The study of the functioning of the venous muscle pump by means of plethysmographic tests allowed us to discover a clearly marked condition in the varicose veins combined with chronic venous deficiency and in the thromboses of the deep veins. (unboundmedicine.com)
- This talk will discuss venous anatomy, the pathophysiology of venous disease and the modern treatment of venous insufficiency and varicose veins. (pri-med.com)
- The venous system of the lower extremities is composed of deep veins that lie within the muscular compartments and superficial veins that lie closer to the skin. (nutritionmd.org)
- Venous insufficiency is a disorder of the deep veins, whereas varicose veins are a disorder of the superficial veins. (nutritionmd.org)
- The development of varicose veins is closely linked to venous insufficiency and can prove to be a painful and aesthetically displeasing condition for many people. (stlouislaserveins.com)
- Chronic venous insufficiency is a condition in which the veins do not efficiently return blood from the legs to the heart, resulting in blood 'pooling' in leg veins. (verywellhealth.com)
- Venous insufficiency is a chronic condition in which blood does not flow normally up through the veins in the legs toward the heart. (nyp.org)
- The incidence of venous insufficiency rises with age, and is also linked to a family history of varicose veins, a sedentary lifestyle, or to jobs that require people to spend many hours on their feet. (nyp.org)
- Venous insufficiency can also be caused by a partial blockage of the veins, for example by a blood clot (a condition called deep vein thrombosis or DVT). (nyp.org)
- Chronic venous insufficiency is when veins do not pump enough oxygen -poor blood back to the heart . (healthtap.com)
- Superficial venous insufficiency is the underlying cause of varicose and spider veins . (healthtap.com)
- Compression stockings can be very useful and actually the primary treatment in those patients with venous insufficiency , whether of the deep veins or the superficial veins. (healthtap.com)
- Venous insufficiency of lower limbs make veins worse? (healthtap.com)
- If you have leg pain, bulging veins and swelling, you could have chronic venous insufficiency, a condition affecting blood flow from leg veins to the heart. (henryford.com)
- Chronic venous insufficiency (CVI) is a condition affecting the veins, which return blood from the body to the heart. (henryford.com)
- redirection of venous flow to the vertebral veins (VVs) occurs in the upright position, with compliant reduction of the CSA of the IJV. (bmj.com)
- Venous return from the lower extremities relies on contraction of calf muscles to push blood from intramuscular (soleal) sinusoids and gastrocnemius veins into and through deep veins. (merckmanuals.com)
- Chronic venous insufficiency occurs when venous obstruction (eg, in DVT ), venous valvular insufficiency, or decreased contraction of muscles surrounding the veins (eg, due to immobility) decrease forward venous flow and increase venous pressure (venous hypertension). (merckmanuals.com)
- In this regard, Daflon would be especially useful for symptomatic relief in patients with functional venous insufficiency who do not have clinical evidence of varicose veins but suffer from symptoms of venous insufficiency. (nih.gov)
- They can signify a more serious problem such as chronic venous insufficiency (CVI)-when veins in the legs become weak and stop working properly. (medstarhealth.org)
- Venous insufficiency can develop even if veins aren't visible on the skin. (medstarhealth.org)
- Throbbing, swollen legs and visible #veins can be a sign of venous insufficiency-when weak veins don't work properly, causing blood to pool in the legs. (medstarhealth.org)
- Your physician will perform a physical exam and review your medical history to determine the severity of your varicose veins and if chronic venous insufficiency (CVI) is present. (templehealth.org)
- Venous insufficiency (VI) is incompetence of the veins that occurs because of dilation, or enlargement, of the veins and dysfunction of their valves. (veindirectory.org)
- Spider veins and varicose veins are common signs of early-stage chronic venous disease. (lifeextension.com)
- Therefore, varicose veins and chronic venous disease should be taken seriously even in the early stages. (lifeextension.com)
- CHIVA , a French acronym for "conservative hemodynamic cure for venous insufficiency," is unique among venous disease treatments in that it preserves rather than destroys superficial veins. (lifeextension.com)
- Chronic venous insufficiency is often a complication of deep vein thrombosis and is caused when the varicose veins in the legs become damaged. (hankeylawoffice.com)
- The specific objectives were to determine which risk factors were associated with deterioration of venous disease and venous reflux, and to ascertain the natural history of asymptomatic venous incompetence in terms of deteriorating to overt trunk varicose veins and chronic venous insufficiency. (bl.uk)
- Importantly, the biophysical analysis of cerebral venous outflow implies that the brain cannot easily compensate for increased peripheral venous resistance (namely, an occlusion of the large extracranial veins draining this organ), either by elevating the pressure gradient or by decreasing the vascular resistance through the recruitment of additional drainage pathways. (eurekaselect.com)
- It has clinically shown to contract the veins and arteries in the lower legs that may help manage the symptoms of Chronic Venous Insufficiency (CVI). (tasmanhealth.co.nz)
- It also provides venous support for haemorrhoids and spider veins. (tasmanhealth.co.nz)
- In venous insufficiency, the valves in the veins have become damaged. (medicalrecords.com)
- Prevalence of varicose veins and chronic venous insufficiency in men and women in the general population: Edinburgh Vein Study. (bmj.com)
- STUDY OBJECTIVE: To determine the prevalence of varicose veins and chronic venous insufficiency (CVI) in the general population. (bmj.com)
- In contrast with the findings in most previous studies, mainly conducted in the 1960s and 1970s, chronic venous insufficiency and mild varicose veins were more common in men than women. (bmj.com)
CCSVI4
- CDMS is strongly associated with CCSVI, a scenario that has not previously been described, characterised by abnormal venous haemodynamics determined by extracranial multiple venous strictures of unknown origin. (bmj.com)
- 1500 examinations for CCSVI research, I have matched 90% of abnormalities to patients with MS. Half of these were post-percutaneous venous angioplasty controls, all of whom submitted to venographic examinations that confirmed CCSVI. (ajnr.org)
- PlacidWay Medical Tourism provides top articles for CCSVI (Chronic Cerebral Spinal Venous Insufficiency), Neurology in France to patients from around the world. (placidway.com)
- Considering that CCSVI is a new entity and has yet to be defined, besides the ultrasound, we have used MDCT angiography to register and evaluate extracranial venous pathway obstruction in patients with MS. 3 MDCT proved to be a very reliable procedure for extracranial venous intraluminal obstruction and extraluminal compression diagnosis. (ajnr.org)
Multiple sclerosis4
- Zamboni P, Menegatti E, Galeotti R et al (2009) The value of cerebral Doppler venous haemodynamics in the assessment of multiple sclerosis. (springer.com)
- Zamboni P (2006) The big idea: iron-dependent inflammation in venous disease and proposed parallels in multiple sclerosis. (springer.com)
- Singh AV, Zamboni P (2009) Anomalous venous blood flow and iron deposition in multiple sclerosis. (springer.com)
- The extracranial venous outflow routes in clinically defined multiple sclerosis (CDMS) have not previously been investigated. (bmj.com)
Vein34
- Gasparis AP, Tsintzilonis S, Labropoulos N. Extraluminal lipoma with common femoral vein obstruction: a cause of chronic venous insufficiency. (medscape.com)
- With long-term (chronic) venous insufficiency, vein walls are weakened and valves are damaged. (medlineplus.gov)
- Dalsing MC, Maleti O. Chronic venous insufficiency: deep vein valve reconstruction. (medlineplus.gov)
- Contact our vein clinic now to get chronic venous insufficiency treatment! (reference.com)
- The electrode radiates high frequency energy towards the vein, and the surrounding venous tissue becomes heated and begins to shrink. (google.de)
- After treating one section of the vein, the catheter and the electrode can be repositioned intraluminally within the vein to treat different sections of the vein until all desired venous sections and valves are repaired and rendered functionally competent. (google.de)
- a plurality of bowable members having sufficient strength to limit the reduction in the diameter of the vein so that the vein remains patent for continued venous function. (google.de)
- Variations in lower limb venous anatomy: implications for US diagnosis of deep vein thrombosis. (springer.com)
- Zamboni P, Gianesini S. Surgical technique for deep venous reflux suppression in femoral vein duplication. (springer.com)
- Prevalence of deep venous reflux in patients with primary superficial vein incompetence. (springer.com)
- Incidence and risk factors for venous reflux in the general population: Edinburgh vein study. (springer.com)
- Zamboni P. Reflux elimination without any ablation or disconnection of the saphenous vein: a hemodynamic model for venous surgery. (springer.com)
- In: Zamboni P., Mendoza E., Gianesini S. (eds) Saphenous Vein-Sparing Strategies in Chronic Venous Disease. (springer.com)
- If the impaired vein function causes significant symptoms, such as swelling and ulcer formation, it is referred to as chronic venous disease. (wikipedia.org)
- Arteriovenous fistula (an abnormal connection or passageway between an artery and a vein) may cause chronic venous insufficiency even with working vein valves. (wikipedia.org)
- Novant Health Vein Specialists is launching a new campaign designed to educate the public about venous insufficiency. (prweb.com)
- Dr. Ray Workman, a leading vein doctor at Novant Health Vein Specialists, cites obesity, inactivity, and standing or sitting in the same position for extended periods of time as key risk factors for venous insufficiency. (prweb.com)
- Novant Health Vein Specialists is utilizing social media to help spread the word about the importance of venous insufficiency prevention. (prweb.com)
- I've been diagnosed with vein insufficiency for several years now. (veindirectory.org)
- Out of these 48 patients, fifteen (15) showed deep venous system involvement with deep vein thrombosis (DVT). (biomedsearch.com)
- Popliteal vein entrapment presenting as deep venous thrombosis and chronic venous insufficiency. (biomedsearch.com)
- PURPOSE: This report describes popliteal vein entrapment in three patients and demonstrates that it may present with manifestations of typical venous disease. (biomedsearch.com)
- Air plethysmography revealed ambulatory venous hypertension, whereas venography demonstrated reflux down to the knee with an extrinsic narrowing at the midpopliteal vein. (biomedsearch.com)
- CONCLUSIONS: The three cases presented demonstrate that popliteal venous entrapment may begin with symptoms of deep vein thrombosis and CVI. (biomedsearch.com)
- Where vein stripping was once a popular choice amongst physicians looking to treat venous insufficiencies, this painful practice is no longer the norm and today, patients have a variety of minimally invasive options to choose from. (stlouislaserveins.com)
- Risk factors for chronic venous insufficiency include a history of deep vein thrombosis in the legs, obesity, and pregnancy. (verywellhealth.com)
- The Henry Ford Vein Center is the only comprehensive program in southeast and south central Michigan for managing venous conditions. (henryford.com)
- This most commonly results from venous reflux due to faulty valve function developing as a long-term sequela of deep vein thrombosis (DVT) and recanalization, and may also develop due to primary valvular incompetence without previous episode(s) of DVT. (bmj.com)
- A simple vein screening and a consultation with one of our specialists can help diagnose venous insufficiency and allow for simple treatments to relieve many of these symptoms. (okheart.com)
- What causes venous insufficiency or vein disease? (okheart.com)
- Oklahoma Heart Hospital's venous disease experts can screen for and treat both superficial and deep vein issues, which sets us apart from many other providers. (okheart.com)
- Contact the Oklahoma Heart Hospital at 405-608-3800 and ask for one of the venous disease experts and schedule a consultation or inquire about vein screening services. (okheart.com)
- Information collected on each subject at a follow-up clinic included lifestyle factors and medical history, height and weight measurement (by means of a questionnaire), clinical examination for classification of venous disease according to the Basle and CEAP systems, and duplex scanning to assess incompetence of venous valves in the deep and superficial systems of ten vein segments in each leg. (bl.uk)
- In Europe, it has long been used as herbal remedy for leg vein health in Chronic Venous Insufficiency (CVI). (tasmanhealth.co.nz)
Doppler9
- A duplex ultrasound (doppler ultrasonography and b-mode) can detect venous obstruction or valvular incompetence as the cause, and is used for planning venous ablation procedures, but it is not necessary in suspected venous insufficiency where surgical intervention is not indicated. (wikipedia.org)
- Your doctor can diagnose venous insufficiency by examining your legs and by using a type of ultrasound test (duplex Doppler) to find out how well blood is flowing in your legs. (peacehealth.org)
- I had the venous doppler test, which revealed reflux. (veindirectory.org)
- Pulsed-Doppler interrogation differentiates venous from arterial flow and documents venous flow pattern and flow direction and timing of duration of venous reflux. (clinicaladvisor.com)
- Compression sonography and color and PW Doppler are systematically employed to assess the absence of deep venous thrombosis. (unboundmedicine.com)
- Diagnosing venous insufficiency generally beings with a thorough exam followed up with a Doppler ultrasound to map blood flow and pinpoint any valve malfunctions or pooling areas. (stlouislaserveins.com)
- Doppler ultrasound was used to investigate venous drainage in 276 people with and without MS. Using the criteria described by Zamboni for the diagnosis of CCVSI, UTHealth researchers found less prevalence of CCVSI than in some previous studies and no statistical difference between those with MS and those without MS. Detailed experience with the other imaging approaches are being readied for publication. (healthcanal.com)
- Sixty-five patients affected by CDMS, and 235 controls composed, respectively, of healthy subjects, healthy subjects older than CDMS patients, patients affected by other neurological diseases and older controls not affected by neurological diseases but scheduled for venography (HAV-C) blindly underwent a combined transcranial and extracranial colour-Doppler high-resolution examination (TCCS-ECD) aimed at detecting at least two of five parameters of anomalous venous outflow. (bmj.com)
- We aimed to evaluate inter-rater agreement in a colour-Doppler sonography venous examination. (bmj.com)
Ulcer10
- Abbade LP, Lastoria S, Rollo Hde A. Venous ulcer: clinical characteristics and risk factors. (medscape.com)
- Ulcer due to venous insufficiency. (medscape.com)
- Chronic venous stasis ulcer. (medscape.com)
- Venous stasis ulcer and surrounding dystrophic tissue. (medscape.com)
- Category 5 is a history of a previously healed venous ulcer. (reference.com)
- Category 6 is an active venous stasis ulcer. (reference.com)
- Malignancy, malignant degeneration being a rare but important complication of venous disease since tumors which develop in the setting of an ulcer tend to be more aggressive. (wikipedia.org)
- CONCLUSIONS: Superficial venous incompetence plays a major role in venous ulcer formation and that location and type of venous disease should be thoroughly investigated as surgical excision of the superficial system leads to a long standing recurrence free period. (biomedsearch.com)
- Whe a venous ulcer begins to develop, stasis dermatitis may be present causing scaling and erythema of the lower extremities. (woundsource.com)
- The base of the ulcer is typically red, can result in a significant amount of exudate depending on the level of infection , and will ooze venous blood when manipulated. (woundsource.com)
Incompetence6
- Venous insufficiency syndromes are most commonly caused by valvular incompetence in the low-pressure superficial venous system (see the image below) but may also be caused by valvular incompetence in the high-pressure deep venous system (or, rarely, both). (medscape.com)
- Surgery for deep venous incompetence. (springer.com)
- Syndromes related to venous insufficiency are caused by valve incompetence. (thefreedictionary.com)
- Chronic venous insufficiency (CVI) is a pathologic condition caused by valvular incompetence, with or without associated venous outflow obstruction, which may affect both the superficial and the deep venous system, causing venous hypertension and stasis. (unboundmedicine.com)
- Causes of chronic venous insufficiency are disorders that result in venous hypertension, usually through venous damage or incompetence of venous valves, as occurs (for example) after DVT. (merckmanuals.com)
- They all had primary venous insufficiency with no venous obstruction, and mixed deep and superficial venous incompetence was found in 64% of the limbs. (nih.gov)
Reflux11
- If this sounds like you, you may be suffering from a common condition called venous insufficiency, also known as venous reflux disease. (reference.com)
- Meissner MH, Manzo RA, Bergelin RO, Markel A, Strandness DE Jr. Deep venous insufficiency: the relationship between lysis and subsequent reflux. (springer.com)
- The most common cause of CVI is superficial venous reflux which is a treatable condition. (wikipedia.org)
- Insufficiency within a venous segment is defined as reflux of more than 0.5 seconds with distal compression. (wikipedia.org)
- Venous plethysmography can assess for reflux and muscle pump dysfunction but the test is laborious and rarely done. (wikipedia.org)
- The evidence supporting treatment of reflux and obstruction in chronic venous disease. (harvard.edu)
- Thirty three (33) patients had venous reflux in the superficial or deep systems without occlusion. (biomedsearch.com)
- One of the most common treatments is compression therapy , which serves to decrease blood vessel diameter and pressure, increasing effectiveness and in turn preventing venous reflux. (woundsource.com)
- Distribution and quantification of venous reflux in lower extremity chronic venous stasis disease wi. (biomedsearch.com)
- The primary stage of the disease is the result of increased and sustained venous hypertension caused mostly by reflux due to incompetent venous valves. (hindawi.com)
- BACKGROUND: The aim of our research has been to verify the role of possible sources of non-saphenous reflux on the appearance of reticular varices and telangiectases, also in points different from the lateral venous system of Albanese, studied by other authors. (minervamedica.it)
Ulceration8
- In patients with early venous insufficiency, progression to overt signs of disease (eg, stasis dermatitis, skin breakdown, and ulceration) can virtually always be prevented with the use of compression hose that provide a pressure gradient of 30-40 mm Hg between foot and knee. (medscape.com)
- Porter M. A case study of venous leg ulceration. (medscape.com)
- Brouse NL, Burnand GJ (1982) The cause of venous ulceration. (springer.com)
- Coleridge Smith PD, Thomas P, Scurr JH, Dormandy JA (1988) Causes of venous ulceration: a new hypothesis. (springer.com)
- Special attention is also given to the treatment of venous ulceration, as well as issues related to venous disease and the elderly. (pri-med.com)
- Chronic venous insufficiency may be complicated by ulceration of the skin of the involved extremity. (ahajournals.org)
- More severe cases exhibit progressive skin changes, venous stasis dermatitis, lipodermatosclerosis, and frank ulceration. (bmj.com)
- Venous ulceration and bleeding are recognized complications. (bmj.com)
Severe chronic venous insuff2
- Tsai S, Dubovoy A, Wainess R. Severe chronic venous insufficiency: magnitude of the problem and consequences. (medscape.com)
- Primary varicosities merge into more severe chronic venous insufficiency. (powershow.com)
Hypertension6
- Under normal conditions, two major mechanisms in the body operate to prevent venous hypertension. (medscape.com)
- History and examination by a clinician for characteristic signs and symptoms are sufficient in many cases in ruling out systemic causes of venous hypertension such as hypervolemia and heart failure. (wikipedia.org)
- The resulting venous hypertension causes blood pooling when it is not as efficiently pumped back towards the heart, otherwise known as venous insufficiency. (woundsource.com)
- Venous hypertension is responsible for most of the symptoms associated with venous disease. (thefreedictionary.com)
- Fluid accumulation in the lower extremities (eg, in right heart failure) can also contribute by causing venous hypertension. (merckmanuals.com)
- While these have been shown to reduce swelling caused by venous hypertension, their effect on venous symptoms is less clear ( 2 ). (acpjc.org)
Thrombosis7
- Deep venous thrombosis (DVT) commonly occurs at these valves, causing irreversible damage to the valve. (medscape.com)
- Recent findings published in the journal of Clinical and Applied Thrombosis/Hematosis show a significant symptom reduction of chronic venous insufficiency (CVI) in patients after supplementing with Pycnogenol® (pic-noj-en-all), an antioxidant plant extract from the bark of the French maritime pine tree. (eurekalert.org)
- Duplex sonography of vascularization of venous thrombosis. (biomedsearch.com)
- When a thrombosis occurs the valves that regulate venous blood flow become thickened and incompetent, rendering them incapable of regulating back flow of blood. (thefreedictionary.com)
- Edema of the affected leg or foot, ulcerations, deep venous thrombosis, pigmentation and pain . (lymphedemapeople.com)
- This condition can predispose to venous thrombosis. (lymphedemapeople.com)
- Postphlebitic (postthrombotic) syndrome is symptomatic chronic venous insufficiency after deep venous thrombosis (DVT). (merckmanuals.com)
Disorders7
- Chronic venous disorders: nonoperative management. (medlineplus.gov)
- In: Venous Disorders of the Legs. (springer.com)
- In a 2017 study published in International Angiology , for example, researchers analyzed 10 previously published studies on the use of Ruscus extract in people with chronic venous disorders. (verywellhealth.com)
- Diosmin is a natural flavonoid applied in vascular system disorders, especially in chronic venous insufficiency (CVI), and it plays a significant part in the alleviation of CVI symptoms. (hindawi.com)
- Venous disorders are divided into acute thromboembolic events or chronic stasis. (powershow.com)
- One of the most common circulatory disorders is venous insufficiency, which is also commonly associated with bilateral leg edema. (veindirectory.org)
- Oxerutin , a mixture of semisynthetic flavonoids derived from rutin, is commonly used in Europe in the treatment of venous disorders. (lifeextension.com)
Superficial venous insufficiency2
- Lattimer CR, Azzam M, Kalodiki E, Makris GC, Geroulakos G. Saphenous pulsation on duplex may be a marker of severe chronic superficial venous insufficiency. (medscape.com)
- Superficial venous insufficiency with skin changes. (medscape.com)
Obstruction3
- Electrical impedance plethysmography (IPG) provides a functional evaluation for outflow obstruction ultrasound (a machine that transmits sound waves) studies can visualize the venous system in certain areas. (thefreedictionary.com)
- The third patient, a 17-year-old male, was seen with severe symptoms of right leg CVI and venous obstruction since 3 years of age. (biomedsearch.com)
- In addition to MDCT, during venous percutaneous angioplasty we measured gradient pressures before and after the venoplasty at various obstruction levels to confirm hemodynamic significance of the diagnosed lesions. (ajnr.org)
Treatments2
- Most cases of CVI can be improved with treatments to the superficial venous system or stenting the deep system. (wikipedia.org)
- Treatments for venous insufficiency are aimed at reducing swelling and improving the return of blood to the heart. (nyp.org)
Ankles2
- Symptoms of venous insufficiency include swollen ankles, tight calves, and an aching or heaviness in the legs. (cardiosmart.org)
- As the condition progresses, people with venous insufficiency develop brown patches and deteriorating (flaking or hardening) skin around the ankles. (nyp.org)
Disease29
- Matic M, Matic A, Djuran V, Gajinov Z, Prcic S, Golusin Z. Frequency of Peripheral Arterial Disease in Patients With Chronic Venous Insufficiency. (medscape.com)
- Venous thromboembolism and other venous disease in the Tecumseh community health study. (medscape.com)
- Venous disease. (medlineplus.gov)
- Updated by: Deepak Sudheendra, MD, RPVI, FSIR, Director of DVT & Complex Venous Disease Program, Assistant Professor of Interventional Radiology & Surgery at the University of Pennsylvania Perelman School of Medicine, with an expertise in Vascular Interventional Radiology & Surgical Critical Care, Philadelphia, PA. (medlineplus.gov)
- However, these terms have been largely abandoned because they do not include another common cause of the disease, the congenital absence of venous valves. (medscape.com)
- 15+ pictures of venous insufficiency to help you understand the stages and classifications of the disease. (reference.com)
- Coleridge Smith PD eds (1993) Microcirculation in Venous Disease. (springer.com)
- Deep Venous Insufficiency (DVI) is a chronic disease that can result in significant morbidity. (reference.com)
- Chronic Venous Disease (CVD) occurs after years of venous disease or abnormality. (reference.com)
- The hemodynamics and diagnosis of venous disease. (springer.com)
- Pain, a feature of venous disease often overlooked and commonly undertreated. (wikipedia.org)
- Sulodexide in venous disease. (harvard.edu)
- Chronic Venous Insufficiency: Novel Management Strategies for an Under-diagnosed Disease Process. (harvard.edu)
- There are several techniques used to diagnose venous disease. (thefreedictionary.com)
- Popliteal venous entrapment must be considered in the differential diagnosis of venous disease in younger patients in whom common predisposing factors are absent. (biomedsearch.com)
- The location of venous obstructions plays a key role in determining the clinical course of the disease. (bmj.com)
- Prescription-strength garments are recommended for anyone with venous disease. (medstarhealth.org)
- Varicosities are a symptom of venous disease, not just a cosmetic problem. (powershow.com)
- The early stages of venous disease may have no symptoms. (lifeextension.com)
- Some potential complications of venous disease, such as DVT, can occur even in people who have no overt signs. (lifeextension.com)
- Multiple clinical trials have demonstrated that oxerutin reduces edema and pain associated with venous disease. (lifeextension.com)
- In order to assign priorities and target interventions properly, authorities need to know which patients with venous disease will progress. (bl.uk)
- Although many epidemiological studies have investigated the prevalence of venous disease, information on deterioration is scarce. (bl.uk)
- The overall aim of this study is to determine the natural history of venous disease in the population and to identify lifestyle and clinical factors related to deterioration which might aid clinical decision making and health services policy. (bl.uk)
- Chronic venous diseases (CVI) are one of the most frequent diseases in populations of industrialized countries, but only a few studies have addressed the burden of disease in the general population. (egms.de)
- Norrie disease gene mutation in a large Costa Rican kindred with a novel phenotype including venous insufficiency. (harvard.edu)
- Rehm HL, Gutiérrez-Espeleta GA, Garcia R, Jiménez G, Khetarpal U, Priest JM, Sims KB, Keats BJ, Morton CC. Norrie disease gene mutation in a large Costa Rican kindred with a novel phenotype including venous insufficiency. (harvard.edu)
- Changes in lifestyle or other factors might be contributing to an alteration in the epidemiology of venous disease. (bmj.com)
- Background: The Chronic Venous Insufficiency Quality of Life Questionnaire (CIVIQ) is a disease-specific instrument to measure the impact of chronic venous insufficiency (CVI) on patients' lives. (eur.nl)
Symptoms of chronic venous insuff3
- What are the symptoms of chronic venous insufficiency? (hopkinsmedicine.org)
- The symptoms of chronic venous insufficiency may seem like other health conditions. (hopkinsmedicine.org)
- The symptoms of chronic venous insufficiency can be subjective and objective. (thefreedictionary.com)
Diagnosis of chronic venous insuff1
- Describe the advantages and disadvantages of this technique for diagnosis of chronic venous insufficiency. (clinicaladvisor.com)
Associated with chronic venous insuff2
- Bryan LJ, Callas PW, Criqui MH, Cushman M. Higher soluble P-selectin is associated with chronic venous insufficiency: the San Diego Population Study. (medscape.com)
- Oligomeric proanthocyanidin complexes (OPCs), which are compounds found in substances such as pine bark extract and grape seed extract , have been found to reduce leg pain and swelling associated with chronic venous insufficiency. (consumerlab.com)
Vascular3
- Fortunately, the vascular and endovascular surgeons at Cooper University Health Care have extensive experience in successfully treating chronic venous insufficiency using today's most advanced techniques. (cooperhealth.org)
- Through their specialized training and experience, our vascular surgeons are uniquely qualified to provide both minimally invasive endovascular approaches as well as traditional open surgical solutions to treat chronic venous insufficiency. (cooperhealth.org)
- Vascular specialists at Henry Ford have advanced training and expertise in treating chronic venous insufficiency (CVI) and other venous diseases. (henryford.com)
Stasis dermatitis1
- Stasis dermatitis, also known as varicose eczema Contact dermatitis, a disrupted epidermal barrier due to venous insufficiency, making patients more susceptible than the general population to contact sensitization and subsequent dermatitis. (wikipedia.org)
Occurs1
- Venous insufficiency occurs when valves are damaged or not functioning properly. (nyp.org)
Decreased venous return1
- Can venous stasis lead to decreased venous return? (healthtap.com)
Edema4
- Inadequate drainage of venous blood from a part, resulting in edema or dermatosis. (dictionary.com)
- Does arterial insufficiency cause edema like chronic venous insufficiency? (healthtap.com)
- Chronic venous insufficiency is impaired venous return, sometimes causing lower extremity discomfort, edema, and skin changes. (merckmanuals.com)
- The intersection of VI (venous insufficiency) and CHF (congestive heart failure) with edema represents an important and challenging area of differentiation. (veindirectory.org)
Compression stockings4
- The most common treatment for venous insufficiency is compression stockings. (nyp.org)
- Compression stockings help with chronic venous insufficiency? (healthtap.com)
- Elevation of the legs periodically during the day and the use of compression stockings may temporarily help the condition, but ultimately venous insufficiency is a mechanical problem that responds to mechanical solutions commonly performed today such as thermal or chemical energy ablation. (veindirectory.org)
- In patients with chronic venous insufficiency, is oral horse chestnut seed extract (HCSE) more effective in treating symptoms than placebo, compression stockings, or other drugs? (acpjc.org)
Lower extremities1
- As functional venous valves are required to provide for efficient blood return from the lower extremities, this condition typically affects the legs. (wikipedia.org)
People with venous insufficiency2
- However, people with venous insufficiency are advised not to use antibiotic creams because they worsen inflammation. (nyp.org)
- In people with venous insufficiency, these valves become defective and no longer close properly. (okheart.com)
Patients with venous insufficiency2
- In general, patients with venous insufficiency should avoid prolonged standing or sitting. (medscape.com)
- The response to therapy with diuretic drugs in patients with venous insufficiency tends to be unsatisfactory. (veindirectory.org)
Blood11
- Over 35 years of research on Pycnogenol® demonstrate the antioxidant's ability to improve blood flow and strengthen venous walls. (eurekalert.org)
- Impaired venous blood flow or venous return (venous stasis), usually caused by inadequate venous valves. (harvard.edu)
- Chronic venous insufficiency (CVI) is poor return of blood from feet and legs back to the heart. (peacehealth.org)
- When people get chronic venous insufficiency after a blood clot, it may be referred to as post-thrombotic syndrome. (memorialhospitaljax.com)
- An individual who presents with venous insufficiency is one who is experiencing a problem related to blood flow. (stlouislaserveins.com)
- In this scenario, venous insufficiency leads to the development of blood clots that have the potential to break free and cause a pulmonary embolism. (stlouislaserveins.com)
- Mild cases of venous insufficiency may be able to be improved by having a patient regularly wear compression garments such as stockings or sleeves that work to promote overall blood flow and reduce swelling. (stlouislaserveins.com)
- The result is the diversion of venous blood through the graft and into the intact contralateral venous system. (lymphedemapeople.com)
- Venous valves direct blood proximally to the heart. (merckmanuals.com)
- Physical activity encourages return of venous blood from the legs back to the heart by activating the pumping action of the muscles. (lifeextension.com)
- Through protecting this key venous proteins, Horse Chestnut is able to maintain its strength and elasticity for improved blood supply to the legs and enhanced venous return to the heart. (tasmanhealth.co.nz)
Ablation5
- The aim of the study is to compare operative treatment, ultrasound guided laser ablation and ultrasound guided foam sclerotherapy in occluding/ablating of insufficiency in great saphenous trunks. (clinicaltrials.gov)
- Mechanochemical Ablation for Treatment of Truncal Venous Insufficiency: A Review of the Current Literature. (harvard.edu)
- I had Venous Ablation 8 months ago and healed fast with no problems until the last few days. (veindirectory.org)
- The risks of venous ablation treatment are very small and the potential benefit to you is significant, so I would recommend you proceed given the symptoms you are experiencing. (veindirectory.org)
- Symptomatic venous insufficiency not improved by wearing compression is best treated by saphenous ablation sooner rather than later. (veindirectory.org)
Surgical1
- Modulation of Circulating Cytokine-Chemokine Profile in Patients Affected by Chronic Venous Insufficiency Undergoing Surgical Hemodynamic Correction," Journal of Immunology Research , vol. 2014, Article ID 473765, 10 pages, 2014. (hindawi.com)
Incidence1
- Occupations involving prolonged standing also increase the incidence of venous insufficiency. (epnet.com)
Arterial insufficiency2
- Skin changes or ulcerations that are localized to the lateral aspect of the ankle are more likely to be related to prior trauma or arterial insufficiency than to pure venous insufficiency. (medscape.com)
- Arterial insufficiency patients do not typically complain of lower extremity swellling. (healthtap.com)
Drainage1
- The drainage through the extracranial venous outflow routes has not previously been investigated in MS patients. (bmj.com)
Treat venous insufficiency2
- Because venous insufficiency is so closely linked to the potential for further medical issues, it's important to have a doctor evaluate, diagnose and treat venous insufficiency as soon as possible. (stlouislaserveins.com)
- 6 options to treat venous insufficiency symptoms. (medstarhealth.org)
Outflow2
- Zamboni P, Consorti G, Galetti R et al (2009) Venous collateral circulation of the extracranial cerebrospinal outflow routes. (springer.com)
- We present the results of a study that evaluated the abnormalities of the cerebral venous outflow in patients with MS using ECD-TCCS and selective venography. (bmj.com)