Venous Thrombosis: The formation or presence of a blood clot (THROMBUS) within a vein.Thrombosis: Formation and development of a thrombus or blood clot in the blood vessel.Portal Vein: A short thick vein formed by union of the superior mesenteric vein and the splenic vein.Veins: The vessels carrying blood away from the capillary beds.Thrombophlebitis: Inflammation of a vein associated with a blood clot (THROMBUS).Femoral Vein: The vein accompanying the femoral artery in the same sheath; it is a continuation of the popliteal vein and becomes the external iliac vein.Iliac Vein: A vein on either side of the body which is formed by the union of the external and internal iliac veins and passes upward to join with its fellow of the opposite side to form the inferior vena cava.Upper Extremity Deep Vein Thrombosis: DEEP VEIN THROMBOSIS of an upper extremity vein (e.g., AXILLARY VEIN; SUBCLAVIAN VEIN; and JUGULAR VEINS). It is associated with mechanical factors (Upper Extremity Deep Vein Thrombosis, Primary) secondary to other anatomic factors (Upper Extremity Deep Vein Thrombosis, Secondary). Symptoms may include sudden onset of pain, warmth, redness, blueness, and swelling in the arm.Phlebography: Radiographic visualization or recording of a vein after the injection of contrast medium.Mesenteric Veins: Veins which return blood from the intestines; the inferior mesenteric vein empties into the splenic vein, the superior mesenteric vein joins the splenic vein to form the portal vein.Anticoagulants: Agents that prevent clotting.Renal Veins: Short thick veins which return blood from the kidneys to the vena cava.Pulmonary Embolism: Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS.Splenic Vein: Vein formed by the union (at the hilus of the spleen) of several small veins from the stomach, pancreas, spleen and mesentery.Saphenous Vein: The vein which drains the foot and leg.Popliteal Vein: The vein formed by the union of the anterior and posterior tibial veins; it courses through the popliteal space and becomes the femoral vein.Varicose Veins: Enlarged and tortuous VEINS.Subclavian Vein: The continuation of the axillary vein which follows the subclavian artery and then joins the internal jugular vein to form the brachiocephalic vein.Jugular Veins: Veins in the neck which drain the brain, face, and neck into the brachiocephalic or subclavian veins.Sinus Thrombosis, Intracranial: Formation or presence of a blood clot (THROMBUS) in the CRANIAL SINUSES, large endothelium-lined venous channels situated within the SKULL. Intracranial sinuses, also called cranial venous sinuses, include the superior sagittal, cavernous, lateral, petrous sinuses, and many others. Cranial sinus thrombosis can lead to severe HEADACHE; SEIZURE; and other neurological defects.Intracranial Thrombosis: Formation or presence of a blood clot (THROMBUS) in a blood vessel within the SKULL. Intracranial thrombosis can lead to thrombotic occlusions and BRAIN INFARCTION. The majority of the thrombotic occlusions are associated with ATHEROSCLEROSIS.Coronary Thrombosis: Coagulation of blood in any of the CORONARY VESSELS. The presence of a blood clot (THROMBUS) often leads to MYOCARDIAL INFARCTION.Fibrin Fibrinogen Degradation Products: Soluble protein fragments formed by the proteolytic action of plasmin on fibrin or fibrinogen. FDP and their complexes profoundly impair the hemostatic process and are a major cause of hemorrhage in intravascular coagulation and fibrinolysis.Vena Cava, Inferior: The venous trunk which receives blood from the lower extremities and from the pelvic and abdominal organs.Heparin, Low-Molecular-Weight: Heparin fractions with a molecular weight usually between 4000 and 6000 kD. These low-molecular-weight fractions are effective antithrombotic agents. Their administration reduces the risk of hemorrhage, they have a longer half-life, and their platelet interactions are reduced in comparison to unfractionated heparin. They also provide an effective prophylaxis against postoperative major pulmonary embolism.Axillary Vein: The venous trunk of the upper limb; a continuation of the basilar and brachial veins running from the lower border of the teres major muscle to the outer border of the first rib where it becomes the subclavian vein.Thrombophilia: A disorder of HEMOSTASIS in which there is a tendency for the occurrence of THROMBOSIS.Postthrombotic Syndrome: A condition caused by one or more episodes of DEEP VEIN THROMBOSIS, usually the blood clots are lodged in the legs. Clinical features include EDEMA; PAIN; aching; heaviness; and MUSCLE CRAMP in the leg. When severe leg swelling leads to skin breakdown, it is called venous STASIS ULCER.Cerebral Veins: Veins draining the cerebrum.Carotid Artery Thrombosis: Blood clot formation in any part of the CAROTID ARTERIES. This may produce CAROTID STENOSIS or occlusion of the vessel, leading to TRANSIENT ISCHEMIC ATTACK; CEREBRAL INFARCTION; or AMAUROSIS FUGAX.Budd-Chiari Syndrome: A condition in which the hepatic venous outflow is obstructed anywhere from the small HEPATIC VEINS to the junction of the INFERIOR VENA CAVA and the RIGHT ATRIUM. Usually the blockage is extrahepatic and caused by blood clots (THROMBUS) or fibrous webs. Parenchymal FIBROSIS is uncommon.Ultrasonography, Doppler, Duplex: Ultrasonography applying the Doppler effect combined with real-time imaging. The real-time image is created by rapid movement of the ultrasound beam. A powerful advantage of this technique is the ability to estimate the velocity of flow from the Doppler shift frequency.Venous Thromboembolism: Obstruction of a vein or VEINS (embolism) by a blood clot (THROMBUS) in the blood stream.Pulmonary Veins: The veins that return the oxygenated blood from the lungs to the left atrium of the heart.Heparin: A highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from six to twenty thousand. Heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Its function is unknown, but it is used to prevent blood clotting in vivo and vitro, in the form of many different salts.Factor V: Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thrombin in blood coagulation. Factor V accomplishes this by forming a complex with factor Xa, phospholipid, and calcium (prothrombinase complex). Deficiency of factor V leads to Owren's disease.Protein S Deficiency: An autosomal dominant disorder showing decreased levels of plasma protein S antigen or activity, associated with venous thrombosis and pulmonary embolism. PROTEIN S is a vitamin K-dependent plasma protein that inhibits blood clotting by serving as a cofactor for activated PROTEIN C (also a vitamin K-dependent protein), and the clinical manifestations of its deficiency are virtually identical to those of protein C deficiency. Treatment with heparin for acute thrombotic processes is usually followed by maintenance administration of coumarin drugs for the prevention of recurrent thrombosis. (From Harrison's Principles of Internal Medicine, 12th ed, p1511; Wintrobe's Clinical Hematology, 9th ed, p1523)Leg: The inferior part of the lower extremity between the KNEE and the ANKLE.Vena Cava Filters: Mechanical devices inserted in the inferior vena cava that prevent the migration of blood clots from deep venous thrombosis of the leg.Thrombectomy: Surgical removal of an obstructing clot or foreign material from a blood vessel at the point of its formation. Removal of a clot arising from a distant site is called EMBOLECTOMY.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Fibrinolytic Agents: Fibrinolysin or agents that convert plasminogen to FIBRINOLYSIN.Thromboembolism: Obstruction of a blood vessel (embolism) by a blood clot (THROMBUS) in the blood stream.Warfarin: An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.Mesenteric Vascular Occlusion: Obstruction of the flow in the SPLANCHNIC CIRCULATION by ATHEROSCLEROSIS; EMBOLISM; THROMBOSIS; STENOSIS; TRAUMA; and compression or intrinsic pressure from adjacent tumors. Rare causes are drugs, intestinal parasites, and vascular immunoinflammatory diseases such as PERIARTERITIS NODOSA and THROMBOANGIITIS OBLITERANS. (From Juergens et al., Peripheral Vascular Diseases, 5th ed, pp295-6)Hepatic Veins: Veins which drain the liver.Postphlebitic Syndrome: A condition characterized by a chronically swollen limb, often a leg with stasis dermatitis and ulcerations. This syndrome can appear soon after phlebitis or years later. Postphlebitic syndrome is the result of damaged or incompetent venous valves in the limbs. Distended, tortuous VARICOSE VEINS are usually present. Leg pain may occur after long period of standing.Stockings, Compression: Tight coverings for the foot and leg that are worn to aid circulation in the legs, and prevent the formation of EDEMA and DEEP VEIN THROMBOSIS. PNEUMATIC COMPRESSION STOCKINGS serve a similar purpose especially for bedridden patients, and following surgery.Plethysmography, Impedance: Recording changes in electrical impedance between electrodes placed on opposite sides of a part of the body, as a measure of volume changes in the path of the current. (Stedman, 25th ed)Intermittent Pneumatic Compression Devices: Instruments that generate intermittent forces, uniformed or graduated, to facilitate the emptying of VEINS. These devices are used to reduce limb EDEMA and prevent venous THROMBOEMBOLISM, such as deep vein thrombosis in the legs.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Hypertension, Portal: Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.Umbilical Veins: Venous vessels in the umbilical cord. They carry oxygenated, nutrient-rich blood from the mother to the FETUS via the PLACENTA. In humans, there is normally one umbilical vein.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Hemorrhage: Bleeding or escape of blood from a vessel.Activated Protein C Resistance: A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance.Bandages: Material used for wrapping or binding any part of the body.Thrombolytic Therapy: Use of infusions of FIBRINOLYTIC AGENTS to destroy or dissolve thrombi in blood vessels or bypass grafts.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Venous Insufficiency: Impaired venous blood flow or venous return (venous stasis), usually caused by inadequate venous valves. Venous insufficiency often occurs in the legs, and is associated with EDEMA and sometimes with VENOUS STASIS ULCERS at the ankle.Prothrombin: A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa, factor V, phospholipid, and calcium ions. Deficiency of prothrombin leads to hypoprothrombinemia.Sagittal Sinus Thrombosis: Formation or presence of a blood clot (THROMBUS) in the SUPERIOR SAGITTAL SINUS or the inferior sagittal sinus. Sagittal sinus thrombosis can result from infections, hematological disorders, CRANIOCEREBRAL TRAUMA; and NEUROSURGICAL PROCEDURES. Clinical features are primarily related to the increased intracranial pressure causing HEADACHE; NAUSEA; and VOMITING. Severe cases can evolve to SEIZURES or COMA.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Portasystemic Shunt, Surgical: Surgical venous shunt between the portal and systemic circulation to effect decompression of the portal circulation. It is performed primarily in the treatment of bleeding esophageal varices resulting from portal hypertension. Types of shunt include portacaval, splenorenal, mesocaval, splenocaval, left gastric-caval (coronary-caval), portarenal, umbilicorenal, and umbilicocaval.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Lower Extremity: The region of the lower limb in animals, extending from the gluteal region to the FOOT, and including the BUTTOCKS; HIP; and LEG.Ultrasonography, Doppler: Ultrasonography applying the Doppler effect, with frequency-shifted ultrasound reflections produced by moving targets (usually red blood cells) in the bloodstream along the ultrasound axis in direct proportion to the velocity of movement of the targets, to determine both direction and velocity of blood flow. (Stedman, 25th ed)Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Recurrence: The return of a sign, symptom, or disease after a remission.Intracranial Embolism and Thrombosis: Embolism or thrombosis involving blood vessels which supply intracranial structures. Emboli may originate from extracranial or intracranial sources. Thrombosis may occur in arterial or venous structures.Ultrasonography, Doppler, Color: Ultrasonography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image. This type of ultrasonography is well-suited to identifying the location of high-velocity flow (such as in a stenosis) or of mapping the extent of flow in a certain region.Catheterization, Central Venous: Placement of an intravenous CATHETER in the subclavian, jugular, or other central vein.Blood Coagulation: The process of the interaction of BLOOD COAGULATION FACTORS that results in an insoluble FIBRIN clot.Antithrombin III Deficiency: An absence or reduced level of Antithrombin III leading to an increased risk for thrombosis.Enoxaparin: Low-molecular-weight fragment of heparin, having a 4-enopyranosuronate sodium structure at the non-reducing end of the chain. It is prepared by depolymerization of the benzylic ester of porcine mucosal heparin. Therapeutically, it is used as an antithrombotic agent. (From Merck Index, 11th ed)Protein C Deficiency: An absence or deficiency in PROTEIN C which leads to impaired regulation of blood coagulation. It is associated with an increased risk of severe or premature thrombosis. (Stedman's Med. Dict., 26th ed.)Fibrinogen: Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.Antiphospholipid Syndrome: The presence of antibodies directed against phospholipids (ANTIBODIES, ANTIPHOSPHOLIPID). The condition is associated with a variety of diseases, notably systemic lupus erythematosus and other connective tissue diseases, thrombopenia, and arterial or venous thromboses. In pregnancy it can cause abortion. Of the phospholipids, the cardiolipins show markedly elevated levels of anticardiolipin antibodies (ANTIBODIES, ANTICARDIOLIPIN). Present also are high levels of lupus anticoagulant (LUPUS COAGULATION INHIBITOR).Catheterization, Peripheral: Insertion of a catheter into a peripheral artery, vein, or airway for diagnostic or therapeutic purposes.Splenorenal Shunt, Surgical: Anastomosis of splenic vein to renal vein to relieve portal hypertension.Splenectomy: Surgical procedure involving either partial or entire removal of the spleen.Vascular Patency: The degree to which BLOOD VESSELS are not blocked or obstructed.Hemostasis: The process which spontaneously arrests the flow of BLOOD from vessels carrying blood under pressure. It is accomplished by contraction of the vessels, adhesion and aggregation of formed blood elements (eg. ERYTHROCYTE AGGREGATION), and the process of BLOOD COAGULATION.Retinal Vein Occlusion: Blockage of the RETINAL VEIN. Those at high risk for this condition include patients with HYPERTENSION; DIABETES MELLITUS; ATHEROSCLEROSIS; and other CARDIOVASCULAR DISEASES.Esophageal and Gastric Varices: Dilated blood vessels in the ESOPHAGUS or GASTRIC FUNDUS that shunt blood from the portal circulation (PORTAL SYSTEM) to the systemic venous circulation. Often they are observed in individuals with portal hypertension (HYPERTENSION, PORTAL).Pregnancy Complications, Cardiovascular: The co-occurrence of pregnancy and a cardiovascular disease. The disease may precede or follow FERTILIZATION and it may or may not have a deleterious effect on the pregnant woman or FETUS.Ultrasonography: The visualization of deep structures of the body by recording the reflections or echoes of ultrasonic pulses directed into the tissues. Use of ultrasound for imaging or diagnostic purposes employs frequencies ranging from 1.6 to 10 megahertz.Angiography: Radiography of blood vessels after injection of a contrast medium.Liver Transplantation: The transference of a part of or an entire liver from one human or animal to another.Brachiocephalic Veins: Large veins on either side of the root of the neck formed by the junction of the internal jugular and subclavian veins. They drain blood from the head, neck, and upper extremities, and unite to form the superior vena cava.Incidence: The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.Platelet Aggregation Inhibitors: Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.Stents: Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.Acute Disease: Disease having a short and relatively severe course.Fibrin: A protein derived from FIBRINOGEN in the presence of THROMBIN, which forms part of the blood clot.Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Vascular Surgical Procedures: Operative procedures for the treatment of vascular disorders.Fibrinolysis: The natural enzymatic dissolution of FIBRIN.Cavernous Sinus Thrombosis: Formation or presence of a blood clot (THROMBUS) in the CAVERNOUS SINUS of the brain. Infections of the paranasal sinuses and adjacent structures, CRANIOCEREBRAL TRAUMA, and THROMBOPHILIA are associated conditions. Clinical manifestations include dysfunction of cranial nerves III, IV, V, and VI, marked periorbital swelling, chemosis, fever, and visual loss. (From Adams et al., Principles of Neurology, 6th ed, p711)Varicose Ulcer: Skin breakdown or ulceration caused by VARICOSE VEINS in which there is too much hydrostatic pressure in the superficial venous system of the leg. Venous hypertension leads to increased pressure in the capillary bed, transudation of fluid and proteins into the interstitial space, altering blood flow and supply of nutrients to the skin and subcutaneous tissues, and eventual ulceration.Constriction, Pathologic: The condition of an anatomical structure's being constricted beyond normal dimensions.Retinal Vein: Central retinal vein and its tributaries. It runs a short course within the optic nerve and then leaves and empties into the superior ophthalmic vein or cavernous sinus.Hypersplenism: Condition characterized by splenomegaly, some reduction in the number of circulating blood cells in the presence of a normal or hyperactive bone marrow, and the potential for reversal by splenectomy.Nadroparin: A heparin fraction with a mean molecular weight of 4500 daltons. It is isolated from porcine mucosal heparin and used as an antithrombotic agent. (From Merck Index, 11th ed)Graft Occlusion, Vascular: Obstruction of flow in biological or prosthetic vascular grafts.Antibodies, Antiphospholipid: Autoantibodies directed against phospholipids. These antibodies are characteristically found in patients with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; related autoimmune diseases, some non-autoimmune diseases, and also in healthy individuals.Gravity Suits: Double-layered inflatable suits which, when inflated, exert pressure on the lower part of the wearer's body. The suits are used to improve or stabilize the circulatory state, i.e., to prevent hypotension, control hemorrhage, and regulate blood pressure. The suits are also used by pilots under positive acceleration.Blood Coagulation Tests: Laboratory tests for evaluating the individual's clotting mechanism.Azygos Vein: A vein which arises from the right ascending lumbar vein or the vena cava, enters the thorax through the aortic orifice in the diaphragm, and terminates in the superior vena cava.Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.Puerperal Disorders: Disorders or diseases associated with PUERPERIUM, the six-to-eight-week period immediately after PARTURITION in humans.Protein C: A vitamin-K dependent zymogen present in the blood, which, upon activation by thrombin and thrombomodulin exerts anticoagulant properties by inactivating factors Va and VIIIa at the rate-limiting steps of thrombin formation.Portacaval Shunt, Surgical: Surgical portasystemic shunt between the portal vein and inferior vena cava.Antifibrinolytic Agents: Agents that prevent fibrinolysis or lysis of a blood clot or thrombus. Several endogenous antiplasmins are known. The drugs are used to control massive hemorrhage and in other coagulation disorders.Liver Neoplasms: Tumors or cancer of the LIVER.Bleeding Time: Duration of blood flow after skin puncture. This test is used as a measure of capillary and platelet function.Pregnancy Complications, Hematologic: The co-occurrence of pregnancy and a blood disease (HEMATOLOGIC DISEASES) which involves BLOOD CELLS or COAGULATION FACTORS. The hematologic disease may precede or follow FERTILIZATION and it may or may not have a deleterious effect on the pregnant woman or FETUS.Sclerotherapy: Treatment of varicose veins, hemorrhoids, gastric and esophageal varices, and peptic ulcer hemorrhage by injection or infusion of chemical agents which cause localized thrombosis and eventual fibrosis and obliteration of the vessels.Blood Coagulation Disorders: Hemorrhagic and thrombotic disorders that occur as a consequence of abnormalities in blood coagulation due to a variety of factors such as COAGULATION PROTEIN DISORDERS; BLOOD PLATELET DISORDERS; BLOOD PROTEIN DISORDERS or nutritional conditions.Lateral Sinus Thrombosis: Formation or presence of a blood clot (THROMBUS) in the LATERAL SINUSES. This condition is often associated with ear infections (OTITIS MEDIA or MASTOIDITIS) without antibiotic treatment. In developed nations, lateral sinus thrombosis can result from CRANIOCEREBRAL TRAUMA; BRAIN NEOPLASMS; NEUROSURGICAL PROCEDURES; THROMBOPHILIA; and other conditions. Clinical features include HEADACHE; VERTIGO; and increased intracranial pressure.Popliteal Cyst: A SYNOVIAL CYST located in the back of the knee, in the popliteal space arising from the semimembranous bursa or the knee joint.Vascular Malformations: A spectrum of congenital, inherited, or acquired abnormalities in BLOOD VESSELS that can adversely affect the normal blood flow in ARTERIES or VEINS. Most are congenital defects such as abnormal communications between blood vessels (fistula), shunting of arterial blood directly into veins bypassing the CAPILLARIES (arteriovenous malformations), formation of large dilated blood blood-filled vessels (cavernous angioma), and swollen capillaries (capillary telangiectases). In rare cases, vascular malformations can result from trauma or diseases.Thromboplastin: Constituent composed of protein and phospholipid that is widely distributed in many tissues. It serves as a cofactor with factor VIIa to activate factor X in the extrinsic pathway of blood coagulation.Phlebitis: Inflammation of a vein, often a vein in the leg. Phlebitis associated with a blood clot is called (THROMBOPHLEBITIS).Antithrombins: Endogenous factors and drugs that directly inhibit the action of THROMBIN, usually by blocking its enzymatic activity. They are distinguished from INDIRECT THROMBIN INHIBITORS, such as HEPARIN, which act by enhancing the inhibitory effects of antithrombins.Venous Valves: Flaps within the VEINS that allow the blood to flow only in one direction. They are usually in the medium size veins that carry blood to the heart against gravity.Thoracic Outlet Syndrome: A neurovascular syndrome associated with compression of the BRACHIAL PLEXUS; SUBCLAVIAN ARTERY; and SUBCLAVIAN VEIN at the superior thoracic outlet. This may result from a variety of anomalies such as a CERVICAL RIB, anomalous fascial bands, and abnormalities of the origin or insertion of the anterior or medial scalene muscles. Clinical features may include pain in the shoulder and neck region which radiates into the arm, PARESIS or PARALYSIS of brachial plexus innervated muscles, PARESTHESIA, loss of sensation, reduction of arterial pulses in the affected extremity, ISCHEMIA, and EDEMA. (Adams et al., Principles of Neurology, 6th ed, pp214-5).Gastrointestinal Hemorrhage: Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.Portal System: A system of vessels in which blood, after passing through one capillary bed, is conveyed through a second set of capillaries before it returns to the systemic circulation. It pertains especially to the hepatic portal system.Catheters, Indwelling: Catheters designed to be left within an organ or passage for an extended period of time.Superior Sagittal Sinus: The long large endothelium-lined venous channel on the top outer surface of the brain. It receives blood from a vein in the nasal cavity, runs backwards, and gradually increases in size as blood drains from veins of the brain and the DURA MATER. Near the lower back of the CRANIUM, the superior sagittal sinus deviates to one side (usually the right) and continues on as one of the TRANSVERSE SINUSES.Doppler Effect: Changes in the observed frequency of waves (as sound, light, or radio waves) due to the relative motion of source and observer. The effect was named for the 19th century Austrian physicist Johann Christian Doppler.Compression Bandages: Strips of elastic material used to apply pressure to body parts to control EDEMA and aid circulation.Behcet Syndrome: Rare chronic inflammatory disease involving the small blood vessels. It is of unknown etiology and characterized by mucocutaneous ulceration in the mouth and genital region and uveitis with hypopyon. The neuro-ocular form may cause blindness and death. SYNOVITIS; THROMBOPHLEBITIS; gastrointestinal ulcerations; RETINAL VASCULITIS; and OPTIC ATROPHY may occur as well.Ligation: Application of a ligature to tie a vessel or strangulate a part.Hepatic Artery: A branch of the celiac artery that distributes to the stomach, pancreas, duodenum, liver, gallbladder, and greater omentum.Platelet Aggregation: The attachment of PLATELETS to one another. This clumping together can be induced by a number of agents (e.g., THROMBIN; COLLAGEN) and is part of the mechanism leading to the formation of a THROMBUS.Dalteparin: A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.Cranial Sinuses: Large endothelium-lined venous channels situated between the two layers of DURA MATER, the endosteal and the meningeal layers. They are devoid of valves and are parts of the venous system of dura mater. Major cranial sinuses include a postero-superior group (such as superior sagittal, inferior sagittal, straight, transverse, and occipital) and an antero-inferior group (such as cavernous, petrosal, and basilar plexus).Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)Anastomosis, Surgical: Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.Catheterization: Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.Contraceptives, Oral: Compounds, usually hormonal, taken orally in order to block ovulation and prevent the occurrence of pregnancy. The hormones are generally estrogen or progesterone or both.Partial Thromboplastin Time: The time required for the appearance of FIBRIN strands following the mixing of PLASMA with phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides). It is a test of the intrinsic pathway (factors VIII, IX, XI, and XII) and the common pathway (fibrinogen, prothrombin, factors V and X) of BLOOD COAGULATION. It is used as a screening test and to monitor HEPARIN therapy.Drug-Eluting Stents: Stents that are covered with materials that are embedded with chemicals that are gradually released into the surrounding milieu.Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.Arthroplasty, Replacement, Knee: Replacement of the knee joint.Early Ambulation: Procedure to accelerate the ability of a patient to walk or move about by reducing the time to AMBULATION. It is characterized by a shorter period of hospitalization or recumbency than is normally practiced.Arteriovenous Shunt, Surgical: Surgical shunt allowing direct passage of blood from an artery to a vein. (From Dorland, 28th ed)Tissue Plasminogen Activator: A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases.Thrombin Time: Clotting time of PLASMA mixed with a THROMBIN solution. It is a measure of the conversion of FIBRINOGEN to FIBRIN, which is prolonged by AFIBRINOGENEMIA, abnormal fibrinogen, or the presence of inhibitory substances, e.g., fibrin-fibrinogen degradation products, or HEPARIN. BATROXOBIN, a thrombin-like enzyme unaffected by the presence of heparin, may be used in place of thrombin.Protein S: The vitamin K-dependent cofactor of activated PROTEIN C. Together with protein C, it inhibits the action of factors VIIIa and Va. A deficiency in protein S; (PROTEIN S DEFICIENCY); can lead to recurrent venous and arterial thrombosis.Blood Platelets: Non-nucleated disk-shaped cells formed in the megakaryocyte and found in the blood of all mammals. They are mainly involved in blood coagulation.Plasminogen Activators: A heterogeneous group of proteolytic enzymes that convert PLASMINOGEN to FIBRINOLYSIN. They are concentrated in the lysosomes of most cells and in the vascular endothelium, particularly in the vessels of the microcirculation.Predictive Value of Tests: In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.Fusobacterium necrophorum: A species of gram-negative, non-spore-forming bacteria isolated from the natural cavities of man and other animals and from necrotic lesions, abscesses, and blood.Iodine Radioisotopes: Unstable isotopes of iodine that decay or disintegrate emitting radiation. I atoms with atomic weights 117-139, except I 127, are radioactive iodine isotopes.Urokinase-Type Plasminogen Activator: A proteolytic enzyme that converts PLASMINOGEN to FIBRINOLYSIN where the preferential cleavage is between ARGININE and VALINE. It was isolated originally from human URINE, but is found in most tissues of most VERTEBRATES.Prothrombin Time: Clotting time of PLASMA recalcified in the presence of excess TISSUE THROMBOPLASTIN. Factors measured are FIBRINOGEN; PROTHROMBIN; FACTOR V; FACTOR VII; and FACTOR X. It is used for monitoring anticoagulant therapy with COUMARINS.Myeloproliferative Disorders: Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE.Fatal Outcome: Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.Reoperation: A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.Injections, Subcutaneous: Forceful administration under the skin of liquid medication, nutrient, or other fluid through a hollow needle piercing the skin.Antithrombin III: A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.Thrombocythemia, Essential: A clinical syndrome characterized by repeated spontaneous hemorrhages and a remarkable increase in the number of circulating platelets.Rupture, Spontaneous: Tear or break of an organ, vessel or other soft part of the body, occurring in the absence of external force.Case-Control Studies: Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.Portasystemic Shunt, Transjugular Intrahepatic: A type of surgical portasystemic shunt to reduce portal hypertension with associated complications of esophageal varices and ascites. It is performed percutaneously through the jugular vein and involves the creation of an intrahepatic shunt between the hepatic vein and portal vein. The channel is maintained by a metallic stent. The procedure can be performed in patients who have failed sclerotherapy and is an additional option to the surgical techniques of portocaval, mesocaval, and splenorenal shunts. It takes one to three hours to perform. (JAMA 1995;273(23):1824-30)Chi-Square Distribution: A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.Sclerosing Solutions: Chemical agents injected into blood vessels and lymphatic sinuses to shrink or cause localized THROMBOSIS; FIBROSIS, and obliteration of the vessels. This treatment is applied in a number of conditions such as VARICOSE VEINS; HEMORRHOIDS; GASTRIC VARICES; ESOPHAGEAL VARICES; PEPTIC ULCER HEMORRHAGE.Cohort Studies: Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.Serum Globulins: All blood proteins except albumin ( = SERUM ALBUMIN, which is not a globulin) and FIBRINOGEN (which is not in the serum). The serum globulins are subdivided into ALPHA-GLOBULINS; BETA-GLOBULINS; and GAMMA-GLOBULINS on the basis of their electrophoretic mobilities. (From Dorland, 28th ed)Streptokinase: Streptococcal fibrinolysin . An enzyme produced by hemolytic streptococci. It hydrolyzes amide linkages and serves as an activator of plasminogen. It is used in thrombolytic therapy and is used also in mixtures with streptodornase (STREPTODORNASE AND STREPTOKINASE). EC 3.4.-.Lupus Coagulation Inhibitor: An antiphospholipid antibody found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic complications.Platelet Activation: A series of progressive, overlapping events, triggered by exposure of the PLATELETS to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Splenomegaly: Enlargement of the spleen.Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)Vascular Diseases: Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.Splenic Artery: The largest branch of the celiac trunk with distribution to the spleen, pancreas, stomach and greater omentum.Thrombocytopenia: A subnormal level of BLOOD PLATELETS.Flank Pain: Pain emanating from below the RIBS and above the ILIUM.Operative Time: The duration of a surgical procedure in hours and minutes.Liver Circulation: The circulation of BLOOD through the LIVER.Emergency Shelter: Temporary shelter provided in response to a major disaster or emergency.International Normalized Ratio: System established by the World Health Organization and the International Committee on Thrombosis and Hemostasis for monitoring and reporting blood coagulation tests. Under this system, results are standardized using the International Sensitivity Index for the particular test reagent/instrument combination used.Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.Ultrasonography, Interventional: The use of ultrasound to guide minimally invasive surgical procedures such as needle ASPIRATION BIOPSY; DRAINAGE; etc. Its widest application is intravascular ultrasound imaging but it is useful also in urology and intra-abdominal conditions.Fusobacterium Infections: Infections with bacteria of the genus FUSOBACTERIUM.Magnetic Resonance Imaging: Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.Venous Cutdown: Creation of a small incised opening in a vein to permit the passage of a needle or cannula for withdrawal of blood, administration of medication, or in diagnostic or therapeutic catheterization. (Dorland, 28th ed.; Stedman, 26th ed.)Arthroplasty, Replacement, Hip: Replacement of the hip joint.Polycythemia Vera: A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and spleen). In time myelofibrosis occurs.Splanchnic Circulation: The circulation of blood through the BLOOD VESSELS supplying the abdominal VISCERA.Hyperhomocysteinemia: Condition in which the plasma levels of homocysteine and related metabolites are elevated (>13.9 µmol/l). Hyperhomocysteinemia can be familial or acquired. Development of the acquired hyperhomocysteinemia is mostly associated with vitamins B and/or folate deficiency (e.g., PERNICIOUS ANEMIA, vitamin malabsorption). Familial hyperhomocysteinemia often results in a more severe elevation of total homocysteine and excretion into the urine, resulting in HOMOCYSTINURIA. Hyperhomocysteinemia is a risk factor for cardiovascular and neurodegenerative diseases, osteoporotic fractures and complications during pregnancy.Central Cord Syndrome: A syndrome associated with traumatic injury to the cervical or upper thoracic regions of the spinal cord characterized by weakness in the arms with relative sparing of the legs and variable sensory loss. This condition is associated with ischemia, hemorrhage, or necrosis involving the central portions of the spinal cord. Corticospinal fibers destined for the legs are spared due to their more external location in the spinal cord. This clinical pattern may emerge during recovery from spinal shock. Deficits may be transient or permanent.Device Removal: Removal of an implanted therapeutic or prosthetic device.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Radionuclide Imaging: The production of an image obtained by cameras that detect the radioactive emissions of an injected radionuclide as it has distributed differentially throughout tissues in the body. The image obtained from a moving detector is called a scan, while the image obtained from a stationary camera device is called a scintiphotograph.
B. P. Loughridge
Complications of pregnancy
... as a result of a condition known as deep vein thrombosis (DVT). "The clot in Bloom's leg was likely brought on by spending long ... until his sudden death in 2003 after a deep vein thrombosis (DVT) became a pulmonary embolism. David Bloom was born in Edina, ... The Coalition to Prevent Deep-Vein Thrombosis. Retrieved November 27, 2012. Huffington Post: "10 Years Later - Melanie Bloom ...
Stam J (April 2005). "Thrombosis of the cerebral veins and sinuses". The New England Journal of Medicine. 352 (17): 1791-8. ... There are four reasons why this might happen: Thrombosis (obstruction of a blood vessel by a blood clot forming locally) ... Venous thrombosis. Stroke without an obvious explanation is termed "cryptogenic" (of unknown origin); this constitutes 30-40% ... Journal of Thrombosis and Haemostasis. 6 (4): 549-54. PMID 18208534. doi:10.1111/j.1538-7836.2008.02903.x. ...
Deep vein thrombosis: US assessment using vein compression. Radiology 1987;162:191. Cohan, RH; Leder, RA et al. Extravascular ... Postphlebographic thrombosis. Radiology 1981; 140:651. Lensing, A W; Prandoni, P et al. Detection of deep-vein thrombosis by ... Diagnosis of deep-vein thrombosis using duplex ultrasound. Ann Intern Med 1989; III :297. Whittaker, Edmund. A history of the ... Deep veins of the calf: assessment with color Doppler flow imaging. Radiology 1989; 171:481. Polak, JF. Venous thrombosis. In: ...
Deep vein thrombosis (DVT) prophylaxis. DVTs may lead to pulmonary embolism (PE) in knee or hip replacement surgery patients. ... "U.S. FDA Approves Eliquis (apixaban) for the Treatment of Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE), and for the ... It was approved in the U.S. in 2014 for treatment and secondary prophylaxis of deep vein thrombosis (DVT) and pulmonary ... On March 14, 2014, it was approved for the additional use of preventing deep vein thrombosis and pulmonary embolism in people ...
Veins of orbit. Cavernous sinus Cavernous sinus thrombosis Dural venous sinuses Yasuda; et al. (Jun 2008). "Microsurgical ... Superior ophthalmic vein Inferior ophthalmic vein Superficial middle cerebral vein Inferior cerebral vein Sphenoparietal sinus ... There are also connections with the pterygoid plexus of veins via inferior ophthalmic vein, deep facial vein and emissary veins ... Superior and inferior ophthalmic veins Sphenoparietal sinus Superficial middle cerebral veins The veins of exit are to the ...
Factor V Leiden is an important risk factor for venous thromboembolism, that is, deep vein thrombosis or pulmonary embolism. In ... Bauer KA (December 2003). "New pentasaccharides for prophylaxis of deep vein thrombosis: pharmacology". Chest. 124 (6 Suppl): ... further increasing the risk of thrombosis. In fact Factor V Leiden is the most common cause of inherited thrombosis. ... Factor V Leiden increases the risk of venous thrombosis by two known mechanisms. First, activated protein C normally ...
Catastrophic antiphospholipid syndrome
For the treatment of established deep vein thrombosis; central retinal and branch vein thrombosis; priapism; pulmonary ... and thrombosis. A small study compared to ancrod to heparin in preventing thrombosis when given to people undergoing arterial ... It is also indicated for the prevention of deep venous thrombosis after repair of the fractured neck of a femur. For the ... Geraghty, AJ; Welch, K (15 June 2011). "Antithrombotic agents for preventing thrombosis after infrainguinal arterial bypass ...
The patient, a 29 year old lady, was suffering from a renal transplant vein thrombosis and was successfully treated resulting ... Thrombolysis for acute deep vein thrombosis. Cochrane Database Syst Rev. 18; 4: CD002783. Review. Bruen KJ, Ballard JR, Morris ... pulmonary embolism and deep vein thrombosis; it has even been used to restore the blood flow in occluded central venous access ... These buildings housed for many years the Center for Thrombosis and Vascular Research and the VIB Department for Transgene ...
"The origin of deep vein thrombosis: a venographic study." Br J Radiol. 1971 Sep;44(525):653-663. Nicolaides AN, et al. "Venous ... ISBN 978-9963-592-51-7 Nicolaides A. & Sumner D. (1991). Investigations of Patients with Deep Vein Thrombosis and Chronic ... Nicolaides developed a venographic method that demonstrated the soleal veins consistently and the veins of the calf as the site ... stasis and deep-vein thrombosis." Br J Surg. 1972 Sep;59(9):713-717. Description of pneumatic compression devices Archived 5 ...
Primary Budd-Chiari syndrome (75%): thrombosis of the hepatic vein Hepatic vein thrombosis is associated with the following in ... Ultrasound may show obliteration of hepatic veins, thrombosis or stenosis, spiderweb vessels, large collateral vessels, or a ... If all the hepatic veins are blocked, the portal vein can be approached via the intrahepatic part of inferior vena cava, a ... "Hepatic vein thrombosis (Budd-Chiari syndrome)". "The Budd-Chiari syndrome: a review". "Budd-Chiari syndrome: long-term ...
Michael Di Venuto
Homans J. Diseases of the veins. N Engl J Med 1944: 231; 51-60. HOMANS J (January 1954). "Thrombosis of the deep leg veins due ... He described the sign which bears his name in 1944, and reported the first instance of deep venous thrombosis occurring in ... helping to popularise the ligation of the saphenofemoral junction for treatment of varicose veins, and advocating ligation of ... the superficial femoral vein to stop migrating clots causing pulmonary embolus. ...
Cardiovascular & pulmonary physiotherapy
Deep vein thrombosis, or deep venous thrombosis (DVT), is the formation of a blood clot (thrombus) within a deep vein, most ... "Diagnosis and treatment of deep-vein thrombosis". CMAJ. 175 (9): 1087-92. doi:10.1503/cmaj.060366. PMC 1609160 . PMID 17060659 ... Nonspecific signs may include pain, swelling, redness, warmness, and engorged superficial veins. Pulmonary embolism, a ...
Otto Heinrich Warburg
Grant, Brydon (2016-02-02). "Diagnosis of suspected deep vein thrombosis of the lower extremity". UpToDate. Retrieved 2016-02- ... Scarvelis, Dimitrios; Wells, Philip S. (2006-10-24). "Diagnosis and treatment of deep-vein thrombosis". Canadian Medical ... or the dorsiflexion sign is considered a sign of deep vein thrombosis (DVT). It was defined by John Homans in 1941 as ... Baker, W.F. Jr (1998). "Diagnosis of deep venous thrombosis and pulmonary embolism". Med. Clin. North Am. 82 (3, May): 459-476 ...
Denis Parsons Burkitt
Venous diseases include venous thrombosis, chronic venous insufficiency, and varicose veins. Lymphatic diseases include primary ... It also covers arterial thrombosis and embolism; vasculitides; and vasospastic disorders. Naturally, it deals with preventing ... veins and lymphatic vases, and its diseases. In the UK this field is more often termed angiology, and in the United States the ...
It is also implicated in the formation of deep vein thrombosis. As a result of activation, enthothelium releases Weibel-Palade ... Bovill EG, van der Vliet A (2011). "Venous valvular stasis-associated hypoxia and thrombosis: what is the link?". Annu Rev ... López JA, Chen J (2009). "Pathophysiology of venous thrombosis". Thromb Res. 123 (Suppl 4): S30-4. doi:10.1016/S0049-3848(09) ... Thrombosis, and Vascular Biology. 36: 1090-100. doi:10.1161/ATVBAHA.115.306964. PMC 4882253 . PMID 27127201. Alom-Ruiz SP, ...
... complicated by thrombosis of the internal jugular vein, thrombosis of the cerebral veins, and infection of the urogenital and ... Redford ML, Ellis R, Rees CJ (2005). "Fusobacterium necrophorum infection associated with portal vein thrombosis". J Med ... Larsen PD, Chartrand SA, Adickes M (1997). "Fusobacterium necrophorum meningitis associated with cerebral vessel thrombosis". ... researchers agree that this diagnosis should be considered in a septicaemic patient with thrombosis in an unusual site, and ...
These anticoagulants are used to treat patients with deep-vein thrombosis (DVT), pulmonary embolism (PE) and to prevent emboli ... Anticoagulants are often used to treat acute deep vein thrombosis. People using anticoagulants to treat this condition should ... deep vein thrombosis, or both". International Journal of Cardiology. 137 (1): 37-41. doi:10.1016/j.ijcard.2008.06.020. ISSN ... commonly forms an atrial appendage clot Coronary artery disease Deep vein thrombosis - can lead to pulmonary embolism Ischemic ...
About 90% of emboli are from proximal leg deep vein thromboses (DVTs) or pelvic vein thromboses. DVTs are at risk for ... Thrombosis and Vascular Biology. "Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis, ... Together deep vein thrombosis and PE are known as venous thromboembolism (VTE). Efforts to prevent PE include beginning to move ... This involves accessing the venous system by placing a catheter into a vein in the groin and guiding it through the veins by ...
Thomas L. Cleave
Peter H. Lin
Lin, P.H. (2010). "Catheter-directed thrombectomy and thrombolysis for symptomatic lower-extremity deep vein thrombosis". ... His clinical interests primarily involve minimally invasive endovascular therapy of deep vein thrombosis, peripheral arterial ... Lin's research interest is in cellular dysfunction in arterial and venous thrombosis as well as experimental model of ... and thrombolysis in arterial and venous thrombosis research. ...
Hematopoietic stem cell transplantation
The most common severe adverse reactions were pulmonary edema/deep vein thrombosis, splenic rupture, and myocardial infarction ... Blood was drawn peripherally in a majority of patients, but a central line to jugular/subclavian/femoral veins may be used in ... There is now a greater appreciation of the generalized cellular injury and obstruction in hepatic vein sinuses, and hepatic VOD ...
Pulmonary embolism - Simple English Wikipedia, the free encyclopedia
Deep vein thrombosis - a blood clot in a large vein, like a leg vein - is a risk factor for pulmonary embolism ... Having had a deep vein thrombosis (DVT) - a blood clot in a large vein - before ... Journal of Thrombosis and Haemostasis (International Society on Thrombosis and Haemostasis) 9 (4): 867-869. doi:10.1111/j.1538- ... Sometimes a doctor will thread a catheter (a flexible tube) up through a vein and into the lung. Once the doctor finds the clot ...
Wat Phra Dhammakaya
The splenic vein can be affected by thrombosis, presenting some of the characteristics of portal vein thrombosis and portal ... The splenic vein ends in the portal vein, formed when the splenic vein joins the superior mesenteric vein. ... Splenic vein. The splenic vein, here called the "lienal vein", travels from the spleen, above the pancreas, and ends in the ... The splenic vein (formerly the lienal vein) is a blood vessel that drains blood from the spleen, the stomach fundus and part of ...
Cephalic vein thrombosis (blood clot). *Arterial ischemia (shortage of blood supply). *Infection ... The vein is carefully attached to the femoral artery.. *The blood supplies from the graft and the vein leading to the femoral ... The vein is carefully attached to the femoral artery.. *The blood supplies from the flap and the vein leading to the femoral ... A segment of vein going to the patient's groin is "borrowed" to allow easier joining of the graft with the preexisting tissues. ...
APS provokes blood clots (thrombosis) in both arteries and veins as well as pregnancy-related complications such as miscarriage ... In APS patients, the most common venous event is deep vein thrombosis of the lower extremities, and the most common arterial ... A documented episode of arterial, venous, or small vessel thrombosis - other than superficial venous thrombosis - in any tissue ... a) Vascular thrombosis in three or more organs or tissues and. *b) Development of manifestations simultaneously or in less than ...
Հեպարին - Վիքիպեդիա՝ ազատ հանրագիտարան
Heparin, low molecular weight heparin and physical methods for preventing deep vein thrombosis and pulmonary embolism following ... Weitz DS, Weitz JI, Weitz (2010)։ «Update on heparin: what do we need to know?»։ Journal of Thrombosis and Thrombolysis 29 (2 ... Thrombosis Research 126 (6): e409-e417։ ISSN 0049-3848։ PMID 20937523։ doi:10.1016/j.thromres.2010.07.004 ...
Hypertensive kidney disease
Virchow was the first to describe and christen diseases such as leukemia, chordoma, ochronosis, embolism, and thrombosis. He ... that pulmonary thrombi are transported from the veins of the leg and that the blood has the ability to carry such an object. He ... Related to this research, Virchow described the factors contributing to venous thrombosis, Virchow's triad. ... During his six-year period there, he concentrated on his scientific work, including detailed studies on venous thrombosis and ...
Strok bahasa Indonesia, ensiklopedia bebas
Cortical vein thrombosis-dehydration. Puerperium. Infection. Neoplasma dan sejenisnya. *Displasia fibromuskular. *Sindrom ... Hal ini dapat terjadi karena iskemia (berkurangnya aliran darah) dikarenakan oleh penyumbatan (thrombosis, arterial embolism), ... cerebral venous thrombosis, dan spinal cord stroke. ICH lebih lanjut terbagi menjadi parenchymal hemorrhage, hemorrhagic ... cerebral venous sinus thrombosis; stroke saat kehamilan, stroke akibat penggunaan hormon pasca menopause, penggunaan senyawa ...
Chen M, Geng JG (2006). "P-selectin mediates adhesion of leukocytes, platelets, and cancer cells in inflammation, thrombosis, ... to human umbilical vein endothelial cells under flow". Blood. 95 (10): 3146-52. PMID 10807781.. ... Chen M, Geng JG (2006). "P-selectin mediates adhesion of leukocytes, platelets, and cancer cells in inflammation, thrombosis, ...
Fat removal procedures
Clot - Simple English Wikipedia, the free encyclopedia
"Thrombosis. 2013: 640723. doi:10.1155/2013/640723. PMC 3885278. PMID 24455237.. *^ Sanders, Gillian D.; Lowenstern, Angela; ... Sources of these disturbances are either automatic foci, often localized at one of the pulmonary veins, or a small number of ... Examination of the jugular veins may reveal elevated pressure (jugular venous distention). Examination of the lungs may reveal ... minor complications such as the formation of a collection of blood at the site where the catheter goes into the vein (access ...
Thrombosis of the internal jugular vein can be displayed with sonography. Thrombi that have developed recently have low ... The bacteria then invade the peritonsillar blood vessels where they can spread to the internal jugular vein. In this vein, ... The inflammation surrounding the vein and compression of the vein may lead to blood clot formation. Pieces of the potentially ... and in such cases pressure with the ultrasound probe show a non-compressible jugular vein - a sure sign of thrombosis. Also ...
ಟೆಂಪ್ಲೇಟು:Central nervous system navs - ವಿಕಿಪೀಡಿಯ
Vertebral artery dissection
Venous thrombosis /. Thrombophlebitis. *primarily lower limb *Deep vein thrombosis. *abdomen *Hepatic veno-occlusive disease ... From various lines of evidence, it appears that thrombosis and embolism is the predominant problem. ... irregularities in the vessel wall and turbulence increase the risk of thrombosis (the formation of blood clots) and embolism ( ...
People with high levels of factor VIII are at increased risk for deep vein thrombosis and pulmonary embolism. Copper is a ... Fang H, Wang L, Wang H (2007). "The protein structure and effect of factor VIII". Thrombosis Research. 119 (1): 1-13. doi: ... Lavigne-Lissalde G, Schved JF, Granier C, Villard S (October 2005). "Anti-factor VIII antibodies: a 2005 update". Thrombosis ... Antonarakis SE (July 1995). "Molecular genetics of coagulation factor VIII gene and hemophilia A". Thrombosis and Haemostasis. ...
Elice, F; Rodeghiero, F (2012). "Side effects of anti-angiogenic drugs". Thrombosis Research. 129 Suppl 1: 50-3. doi:10.1016/ ... "10-Hydroxy-2-decenoic Acid, a Major Fatty Acid from Royal Jelly, Inhibits VEGF-Induced Angiogenesis in Human Umbilical Vein ... Bruemmer, D. (2012). "Targeting Angiogenesis as Treatment for Obesity". Arteriosclerosis, Thrombosis, and Vascular Biology. 32 ...
Թրոմբոզ - Վիքիպեդիա՝ ազատ հանրագիտարան
Neutrophil Extracellular Traps Promote Deep Vein Thrombosis in Mice.»։ Journal of thrombosis and haemostasis : JTH։ PMID ... Webster GJ; Burroughs AK, Riordan SM (January 2005)։ «Review article: portal vein thrombosis - new insights into aetiology and ... low molecular weight heparin and physical methods for preventing deep vein thrombosis and pulmonary embolism following surgery ... August 2005)։ «Causes and predictors of death in cerebral venous thrombosis»։ Stroke 36 (8): 1720-1725։ PMID 16002765։ doi: ...
Deep Vein Thrombosis & Pulmonary Embolism - Chapter 8 - 2020 Yellow Book | Travelers' Health | CDC
Deep vein thrombosis (DVT) is a condition in which a blood clot develops in the deep veins, most commonly in the lower ... Deep Vein Thrombosis & Pulmonary Embolism. Nimia L. Reyes, Michele G. Beckman, Karon Abe ... The effect of flight-related behaviour on the risk of venous thrombosis after air travel. Br J Haematol. 2009 Feb;144(3):425-9. ... The American College of Chest Physicians published the 9th edition of their Antithrombotic Therapy and Prevention of Thrombosis ...
Recommendations | Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary...
... and deep vein thrombosis (DVT) in people aged 16 and over ... the signs and symptoms of deep vein thrombosis (DVT) and ... Embolism and thrombosis Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or ... Varicose vein surgery. 1.15.8 Be aware that VTE prophylaxis is generally not needed for people undergoing varicose vein surgery ... 1.15.11 If using anti-embolism stockings for people undergoing varicose vein surgery, continue until the person no longer has ...
Deep Vein Thrombosis | DVT | MedlinePlus
... is a blood clot that forms in a vein deep in the body, often in the leg. Learn about the causes, symptoms, and treatments. ... Deep vein thrombosis, or DVT, is a blood clot that forms in a vein deep in the body. Most deep vein clots occur in the lower ... Deep vein thrombosis - discharge (Medical Encyclopedia) Also in Spanish * Deep venous thrombosis (Medical Encyclopedia) Also in ... If the vein swells, the condition is called thrombophlebitis. A deep vein thrombosis can break loose and cause a serious ...
Deep vein thrombosis | The BMJ
Re: Deep vein thrombosis. Figure 1 which shows deep vein thrombosis in the right leg of a patient with leg swelling and ... Re: Deep vein thrombosis. Deep vein thrombosis (DVT) usually starts in the calf but by the time symptoms develop most patients ... Re: Deep vein thrombosis. With regards to the clinical update article Deep Venous Thrombosis by Stubbs et al BMJ 24/02/2018, ... The opportunity to diagnose a deep vein thrombosis. Very motivated by the interesting and didactic article published in BMJ ...
Deep vein thrombosis | The BMJ
Deep vein thrombosis (DVT) commonly affects the lower limb, with clot formation beginning in a deep calf vein and propagating ... Pain, swelling, and redness of the affected limb are common symptoms of deep vein thrombosis (DVT) ... and iliac veins 4%.1 Certain medical conditions listed in box 1 increase the likelihood of clot formation in the deep veins. ... Deep vein thrombosis. BMJ 2018; 360 doi: https://doi.org/10.1136/bmj.k351 (Published 22 February 2018) Cite this as: BMJ 2018; ...
Superficial vein thrombosis - Wikipedia
Superficial vein thrombosis (SVT) is a type of venous thrombosis, or a blood clot in a vein, which forms in a superficial vein ... SVT has a limited clinical significance (in terms of morbidity and mortality) when compared to a deep vein thrombosis (DVT), ... with fondaparinux or enoxaparin is warranted though the benefit for preventing progression of the SVT to a deep vein thrombosis ... Usually there is thrombophlebitis, which is an inflammatory reaction around a thrombosed vein, presenting as a painful ...
Pulmonary Embolism | Deep Vein Thrombosis | MedlinePlus
The cause is usually a blood clot in the leg called deep vein thrombosis. Learn more. ... The cause is usually a blood clot in the leg called a deep vein thrombosis that breaks loose and travels through the ... Using compression stockings to prevent deep vein thrombosis (DVT) *Moving your legs when sitting for long periods of time (such ... Patients Guide to Recovery after Deep Vein Thrombosis or Pulmonary Embolism (American Heart Association) ...
Stop Deep Vein Thrombosis
People who are cooped up during extended periods of travel are at risk for a condition called deep vein thrombosis (DVT) and ... People who are cooped up during extended periods of travel are at risk for a condition called deep vein thrombosis (DVT) and ... People who are cooped up during extended periods of travel are at risk for a condition called deep vein thrombosis (DVT) and ...
deep vein thrombosis - Everything2.com
Deep Vein Thrombosis - Mayo Clinic
Dangers of deep-vein thrombosis
Each year 400,000 Americans develop deep-vein thrombosis (DVT), with approximately half of those cases resulting in a blood ... Each year 400,000 Americans develop deep-vein thrombosis (DVT), with approximately half of those cases resulting in a blood ... Kaufman: DVT refers to the sudden clotting-off of the main veins that drain the legs, arms, abdomen and chest of blood. This ... Kaufman: Unfortunately, almost half of DVT cases are silent, especially if they are small or develop in small veins. The most ...
Deep Vein Thrombosis News, Research
Deep Vein Thrombosis News and Research. RSS Deep vein thrombosis, or DVT, is a blood clot that forms in a vein deep in the body ... Immediate compression therapy could cut risk of complications after deep-vein thrombosis People with deep-vein thrombosis can ... If the vein swells, the condition is called thrombophlebitis. A deep vein thrombosis can break loose and cause a serious ... Research could offer new hope for the prevention, treatment of deep vein thrombosis New University of Birmingham research ...
DVT: How deep vein thrombosis can kill you
What is deep-vein thrombosis (DVT)? - Scientific American
What is deep-vein thrombosis (DVT)?. A new government campaign calls for increased awareness of a killer blood clot. ... Acting Surgeon General Steven Galson issued a call to action this week to make more Americans aware of deep-vein thrombosis, ... Theres warmth to the area because the veins are inflamed. How is DVT diagnosed?. By having a high index of suspicion and ... The things that cause clotting are slow flow of blood, damage to the inside of veins from trauma, like if you were hit in the ...
What are some symptoms of deep vein thrombosis?
deep vein thrombosis (dvt) normally affects just one leg. symptoms include: * unequal swelling, where one leg is larger than ... What are some symptoms of deep vein thrombosis?. ANSWER Deep vein thrombosis (DVT) normally affects just one leg. Symptoms ... What causes deep vein thrombosis (DVT)?. NEXT QUESTION: When is deep vein thrombosis a medical emergency? ...
Deep Vein Thrombosis (DVT): Symptoms, Signs, Causes & Treatment
... and signs of deep vein thrombosis (DVT) and the medications used in treatment. Common symptoms and signs include warm skin, ... Main Article on Deep Vein Thrombosis (DVT) Symptoms and Signs. * Deep Vein Thrombosis. Deep vein thrombosis (DVT) is a blood ... DVT (Deep Vein Thrombosis) and Pulmonary Embolism (PE) Quiz. Take the Deep Vein Thrombosis and Pulmonary Embolism Quiz to learn ... A Visual Guide to Deep Vein Thrombosis. Deep vein thrombosis (DVT) is a dangerous and sometimes fatal blood clot that occurs ...
Deep Vein Thrombosis (DVT) Symptoms, Diagnosis, and Tests
Symptoms of deep vein thrombosis -- a blood clot, often in your leg -- are similar to many other health problems. And half the ... Deep Vein Thrombosis (DVT) Symptoms and Diagnosis. Articles OnDeep Vein Thrombosis. Deep Vein Thrombosis Deep Vein Thrombosis ... American Academy of Orthopaedic Surgeons: "Deep Vein Thrombosis.". American Academy of Family Physicians: "Deep Vein Thrombosis ... Deep vein thrombosis -- a blood clot in a deep vein, often in your leg -- can look like many other health problems. And half ...
Enoxaparin Ups Survival in Cirrhotic Portal Vein Thrombosis
Enoxaparin reduced portal vein thrombosis in patients with advanced cirrhosis, thereby reducing risk for clinical ... Cite this: Enoxaparin Ups Survival in Cirrhotic Portal Vein Thrombosis - Medscape - Nov 15, 2011. ... A new treatment regimen with the low-molecular-weight heparin enoxaparin reduced the incidence of portal vein thrombosis (PVT ... PVT was considered relevant when it was complete or when it involved more than 50% of portal vein diameter and was symptomatic. ...
How to Recognize Deep-Vein Thrombosis | Fox News
... according to the Coalition to Prevent Deep-Vein Thrombosis. While treatment is available, DVT can cause serious disability and ... Deep-vein thrombosis (DVT)��affects approximately 2 million Americans each year, ... While superficial veins are close to the flesh, deep veins are embedded much further below the surface. Deep veins are usually ... Deep-vein thrombosis (DVT)��affects approximately 2 million Americans each year, according to the Coalition to Prevent Deep- ...
Jugular Vein Abnormalities Linked to Venous Sinus Thrombosis
Internal jugular vein abnormalities are a newly identified risk factor for cerebral venous sinus thrombosis, and color Doppler ... Cite this: Jugular Vein Abnormalities Linked to Venous Sinus Thrombosis - Medscape - Jun 07, 2012. ... at its influx into the innominate vein (J1), at the point of the superior thyroid vein influx into the IJV (J2), and at the ... Nineteen (61.3%) patients had annulus stenoses, 9 (29.0%) had hypoplastic IJVs, 2 (6.5%) had a thrombosis in the IJV, and 1 ( ...
Deep Vein Thrombosis Treatment at Home
Treating deep vein thrombosis at home consists of managing it and preventing future clots. Heres what you can do in addition ... Deep vein thrombosis (DVT) is a medical condition that happens when a blood clot forms in a vein. A deep vein blood clot can ... A deep vein thrombosis (DVT) occurs when a blood clot forms in a vein deep inside your body. Learn more about DVT of the upper ... Learn more about the pros and cons of these drugs and the importance of deep vein thrombosis therapy. ...
Hepatic Vein Thrombosis (Budd-Chiari Syndrome)
... is an obstruction in the veins of the liver caused by a blood clot. This condition blocks blood flow from the liver to the ... What is hepatic vein thrombosis?. Hepatic vein thrombosis (HVT) is an obstruction in the hepatic veins of the liver caused by a ... This causes the vein to widen.. Once the vein is wide enough, the surgeon inserts wire mesh into the vein. This holds it open. ... Understanding Hepatic Vein Thrombosis (Budd-Chiari Syndrome). Medically reviewed by Alana Biggers, MD on May 11, 2017. - ...
Deep Vein Thrombosis | Research Center Profiles
Dvt? PE? - Deep Vein Thrombosis - MedHelp
Thrombosis of the cerebral veins and sinuses. - PubMed - NCBI
Thrombosis of the cerebral veins and sinuses.. Stam J1.. Author information. 1. Department of Neurology, Academic Medical ... Thrombosis of the cerebral veins and sinuses. [N Engl J Med. 2005] ... Thrombosis of the cerebral veins and sinuses. [N Engl J Med. 2005] ... Thrombosis of the cerebral veins and sinuses. [N Engl J Med. 2005] ...
Deep vein thrombosis - Wikipedia
Thrombosis associated with the abdominal organs (viscera)-such as portal vein thrombosis, renal vein thrombosis, and Budd- ... Deep vein thrombosis (DVT), is the formation of a blood clot in a deep vein, most commonly the legs. Symptoms may include pain ... including the femoral vein, the popliteal vein, and the iliofemoral vein (as with May-Thurner syndrome). Extensive lower- ... With arterial thrombosis, blood vessel wall damage is required, as it initiates coagulation, but clotting in the veins mostly ...
Blood clot symptoms: Deep vein thrombosis and pulmonary embolism
These can dislodge and cause conditions such as deep vein thrombosis (DVT), heart attack, and stroke. Here, we look at the ... This is a deep vein thrombosis (DVT). According to the CDC, deep vein clots are a serious condition that is underdiagnosed but ... Deep vein thrombosis. (2016, April 27). Retrieved from http://www.nhs.uk/Conditions/Deep-vein-thrombosis/Pages/Introduction. ... A deep vein thrombosis - a clot, usually in a lower leg - is one major cause of pulmonary embolism. It occurs when a DVT ...
Deep Vein Thrombosis Treatment (DVT) | Knight Cardiovascular Institute | OHSU
Common treatment approaches for the management of venous thrombosis (DVT) include medical, open surgical and endovascular ... Deep Vein Thrombosis Treatment (DVT) Common treatment approaches for the management of venous thrombosis (DVT) include medical ... In some cases, a vena cava filter may be inserted into the vena cava (the large vein which returns blood from the body to the ...
dvt and diabetes - Deep Vein Thrombosis - MedHelp
Deep Vein Thrombosis (DVT) | Lab Tests Online
... is the formation of a blood clot in a vein. Learn about risk factors, signs and symptoms, and lab tests associated with DVT. ... DVT (Deep Vein Thrombosis) is the formation of a blood clot in a vein. Most DVTs originate in a deep vein in the calf or thigh ... Deep Vein Thrombosis. OrthoInfo. Available online at https://orthoinfo.aaos.org/en/diseases--conditions/deep-vein-thrombosis. ... Waldron, B. and Moll, S. (2014 April 29). A Patients Guide to Recovery After Deep Vein Thrombosis or Pulmonary Embolism. ...
IncidenceUpper extremity deepPrevent Deep Vein ThromClotsCerebral venous sinThrombophlebitisVena cava2018ThrombusUpper extremity deep vein thromThighCaused by deep vein thromSearchCalfMorbidity and mortaPreventionVenous Sinus ThrombosisPatients with clinically suspectedTreatmentClot in a deep veinPelvisChance of getting a blLower limbBlood clot breaksAxillarySpontaneous thrombosisCommonlyLimbJugular veinLarge veinsCancerRiskCatheterSigns
Upper extremity deep1
Prevent Deep Vein Throm1
- Most deep vein clots occur in the lower leg or thigh. (medlineplus.gov)
- DVT can be very serious because blood clots in your veins can break loose, travel through your bloodstream and get stuck in your lungs. (www.nhs.uk)
- Blood thinners are a part of all DVT treatments, but a new approach is to use catheters and X-ray guidance to dissolve or breakup the clots when they involve the veins of the thigh and/or pelvis. (sheknows.com)
- If, for some reason, you cannot be treated with blood thinners or clot-busting drugs, then a metal device called a vena cava filter can be placed in the main vein that drains the blood from the legs to the heart to trap any clots that might break free and cause a PE. (sheknows.com)
- Venous thromboembolism, a term referring to blood clots in the veins, is a highly prevalent and far-reaching public health problem that can cause disability and death. (news-medical.net)
- Acting Surgeon General Steven Galson issued a ' call to action ' this week to make more Americans aware of deep-vein thrombosis, life-threatening blood clots that occur in the legs or pelvis. (scientificamerican.com)
- Most deep vein clots first form in the thighs and lower legs. (foxnews.com)
- A number of conditions��can cause blood clots to form inside deep veins. (foxnews.com)
- In a paper , published in 2010, it was estimated that blood clots in the veins are "a major public health problem that affects an estimated 300,000-600,000 individuals in the United States each year. (medicalnewstoday.com)
- According to the CDC , deep vein clots are a serious condition that is underdiagnosed but preventable. (medicalnewstoday.com)
- Together, DVT and PE are grouped into VTE (venous thromboembolism), blood clots that form in the body's veins but not arteries. (labtestsonline.org)
- Injury to a vein - injury to the walls of veins from fractures, muscle injuries or other trauma can promote formation of blood clots. (labtestsonline.org)
- Deep vein thrombosis, or DVT, is a medical condition in which blood clots (thrombi) form in deep veins, usually of the calf, thigh or pelvis. (wikihow.com)
- The gene produces an enzyme that, if inhibited via a specific drug therapy, could offer hope to patients prone to deep-vein clots, such as those that sometimes form in the legs during lengthy airplane flights or during recuperation after major surgery. (redorbit.com)
- Wang added that, in some individuals, blood clots tend to form within deep veins. (redorbit.com)
- They found that, when veins were constricted, genetically normal mice -- those able to produce the PAD4 enzyme -- formed clots as expected. (redorbit.com)
- First author Kim Martinod, a graduate student in the Immunology Graduate Program at the Harvard University Medical School, found that, in response to vein constriction, these "rescued" mice now could function normally, forming clots as efficiently as mice with a functioning Pad4 gene, demonstrating that the Pad4 gene did produce a functioning PAD4 enzyme in these white blood cells to regulate blood clotting. (redorbit.com)
- This condition results from blood clots in the veins due to blood pooling in the legs from prolonged inactivity. (cbsnews.com)
- Deep vein thrombosis (DVT) is the formation of blood clots within the deep veins in the body. (northshore.org)
- If your symptoms are severe and not responsive to blood thinners you will be referred to an interventional radiologist who will evaluate you and may offer a minimally invasive procedure to dissolve or suck out the clots from your veins to improve blood flow. (northshore.org)
- Clots can form in superficial veins and in deep veins. (adventisthealthcare.com)
- Blood clots with inflammation in superficial veins (called superficial thrombophlebitis or phlebitis) rarely cause serious problems. (adventisthealthcare.com)
- But clots in deep veins (deep vein thrombosis) require immediate medical care. (adventisthealthcare.com)
- Blood clots most often form in the calf and thigh veins, and less often in the arm veins or pelvic veins. (adventisthealthcare.com)
- This topic focuses on blood clots in the deep veins of the legs , but diagnosis and treatment of DVT in other parts of the body are similar. (adventisthealthcare.com)
- What causes deep vein clots to form? (adventisthealthcare.com)
- Blood clots can form in veins when you are inactive. (adventisthealthcare.com)
- If your doctor suspects that you have DVT, you probably will have an ultrasound test to measure the blood flow through your veins and help find any clots that might be blocking the flow. (adventisthealthcare.com)
- At the same time, a stent can be implanted if the vein is very narrow to help prevent future clots. (holyname.org)
- Everything you need to know about blood clots, also known as deep vein thrombosis. (self.com)
- Deep vein thrombosis (DVT) is a condition where blood clots develop usually in the deep veins of the legs. (medindia.net)
- Blood clots may form when something slows or changes the flow of blood in the veins. (upmc.com)
- This happens most often after years of large deep vein clots. (upmc.com)
- There are many simple steps you can take to help stop blood clots from forming and reduce your risk of deep vein thrombosis. (everydayhealth.com)
- Clots can limit the flow of blood in the veins causing pain and swelling. (nuffieldhealth.com)
- Lovenox (enoxaparin sodium) and Xarelto (rivaroxaban) are blood thinners (anticoagulants) used to prevent blood clots that are sometimes called deep vein thrombosis (DVT), which can lead to blood clots in the lungs. (rxlist.com)
- Being inactive for long hours slows down the blood flow in the veins and clots can form. (targetwoman.com)
- Most deep vein blood clots form in the thigh or lower leg but they can occur in other body parts. (consumerinjurylawyers.com)
- If a patient has a number of risk factors, ultrasound, magnetic resonance imaging (MRI) or venography/phlebography (x-ray that identifies the veins and blood clots) are used to screen for DVT. (gwhospital.com)
- Deep venous thrombosis results in PE when the clots break off, travel up to the lungs and get stuck in the arteries, creating a blockage. (ucsd.edu)
Cerebral venous sin1
- If the vein swells, the condition is called thrombophlebitis. (medlineplus.gov)
- Usually there is thrombophlebitis, which is an inflammatory reaction around a thrombosed vein, presenting as a painful thickening and redness of the skin. (wikipedia.org)
- Pycnogenol prevents venous thrombosis and thrombophlebitis in long-haul flights. (greenmedinfo.com)
- A superficial venous thrombosis (also called phlebitis or superficial thrombophlebitis ) is a blood clot that develops in a vein close to the surface of the skin. (clevelandclinic.org)
- If anticoagulant medicines are not suitable, you may have a filter put into a large vein - the vena cava - in your tummy. (www.nhs.uk)
- Your health care provider inserts a filter inside a large vein called the vena cava. (medlineplus.gov)
- In some cases, a vena cava filter may be inserted into the vena cava (the large vein which returns blood from the body to the heart) of patients who cannot take medication or if blood thinners are not working. (ohsu.edu)
- If you can't take blood thinners or they aren't working, your doctor may recommend putting a filter into your biggest vein, called the vena cava. (rxlist.com)
- In some cases, a filter is placed in the vena cava (the large vein which returns blood from the body to the heart). (hopkinsmedicine.org)
- This is when a filter is inserted inside a large vein called the vena cava. (bmc.org)
- The vena cava is a major vein. (epnet.com)
- stents (small tubes) in the vena cava or pelvic veins open a thrombosed vein and help relieve or prevent leg swelling. (upmc.com)
- Imaging studies are done to provide objective verification of the presence of thrombus in the subclavian vein and may include chest radiography, ultrasonography (US), venography, computed tomography (CT), or magnetic resonance imaging (MRI). (medscape.com)
- Ultrasonography showed a thrombus in the left posterior tibial vein. (cmaj.ca)
- Deep vein thrombosis is a blood clot or thrombus in a deep vein. (hopkinsmedicine.org)
- A blood clot (thrombus) in the deep venous system of the leg leads to deep vein thrombosis (DVT). (medindia.net)
- The process of recanalization of the veins of the lower limbs after an episode of acute deep venous thrombosis is part of the natural evolution of the remodeling of the venous thrombus in patients on anticoagulation with heparin and vitamin K inhibitors. (scielo.br)
- This remodeling involves the complex process of adhesion of thrombus to the wall of the vein, the inflammatory response of the vessel wall leading to organization and subsequent contraction of the thrombus, neovascularization and spontaneous lysis of areas within the thrombus. (scielo.br)
- Deep vein thrombosis (DVT) of the lower extremities (LE) is a serious and potentially fatal disease in which there is acute thrombus formation in deep veins of the LE that can cause partial or total obstruction of the venous lumen. (scielo.br)
- According to the Vascular Disease Foundation , DVT occurs when "a blood clot, or thrombus, develops in the large veins of the legs or pelvic area. (gadling.com)
- A thrombus is a blood clot, and thrombosis is the process of developing a clot. (everydayhealth.com)
- In simple terms, DVT or deep vein thrombosis is the formation of thrombus (blood clot) in one of the large/deep veins in the body, predominantly in the lower limbs (the calf or thigh area). (targetwoman.com)
Upper extremity deep vein throm4
- Upper extremity deep vein thrombosis in a triathlete: Again intense endurance exercise as a thrombogenic risk. (tripdatabase.com)
- Improving the diagnostic management of upper extremity deep vein thrombosis. (tripdatabase.com)
- Essentials The Constans score and D-dimer can rule out upper extremity deep vein thrombosis without imaging. (tripdatabase.com)
- The purpose of this study is to document the long-term outcome or prognosis of patients diagnosed with upper extremity deep-vein thrombosis who are treated with Fragmin (dalteparin sodium injection) for three months. (clinicaltrials.gov)
- The things that cause clotting are slow flow of blood, damage to the inside of veins from trauma, like if you were hit in the mid-thigh area hard enough to irritate the inside of the veins, and hypercoaguable states that can lead to increased risk of clotting. (scientificamerican.com)
- A deep vein blood clot can occur anywhere in the body, but most often forms in the calf or thigh. (healthline.com)
- Most DVTs originate in a deep vein in the calf or thigh, but they can also occur in other parts of the body, such as deep veins in the pelvis, abdomen or arms. (labtestsonline.org)
- Deep vein thrombosis (DVT) is the formation of a blood clot within a deep vein, usually in your lower leg or thigh. (hollandandbarrett.com)
- The clot typically forms in a pelvic, thigh or calf vein that returns blood to the heart and lungs, causing leg pain and swelling. (holyname.org)
- Deep vein thrombosis (DVT) is a blood clot that occurs in a vein within the body - most commonly in the large veins of the thigh or lower leg. (upmc.com)
- Deep vein thrombosis (DVT) mainly affects the large veins in the lower leg and thigh. (upmc.com)
- If at least one of the two tests is positive, patients will undergo CUS of the proximal vein system by investigating at least the common femoral vein at the groin, the superficial femoral vein at the mid thigh and the popliteal vein(s) in the popliteal fossa. (clinicaltrials.gov)
Caused by deep vein throm1
- Deep vein thrombosis (DVT) commonly affects the lower limb, with clot formation beginning in a deep calf vein and propagating proximally. (bmj.com)
- Your calf muscles can act like a secondary heart in a sense, helping to pump the blood in the leg veins back up to your actual heart, but only if they are contracting from some type of exercise on a fairly regular basis. (wikihow.com)
- The most common signs and symptoms of DVT include: swelling, redness and pain in the calf or lower leg (especially along the path of a vein), difficulty weight bearing (especially running), and skin that feels warm or hot to touch. (wikihow.com)
- The two-point method is easy to learn and can be done on virtually any ultrasound scanner, although it does need to be repeated to confirm that any isolated calf deep vein thrombosis missed on the first exam hasn't spread, the researchers said. (medpagetoday.com)
- Whole-leg ultrasonography would hold an advantage only if a course of anticoagulant therapy for isolated calf thrombosis was preferable to repeating two-point ultrasonography seven to 10 days later, he said. (medpagetoday.com)
- In the study, the whole-leg method detected deep vein thrombosis more often than the two-point method (26% versus 22%, difference 4.3%, 95% CI 0.5% to 8.1%), which was entirely accounted for by isolated DVT in the calf. (medpagetoday.com)
- The lack of reduction in venous thromboembolism seen in the study and poor evidence for benefit from other studies suggests that "symptomatic but undiagnosed and untreated isolated calf deep vein thrombosis often has a benign course," he said. (medpagetoday.com)
- Only patients with concomitant likely PTP and positive D-dimer will undergo whole-leg ultrasonography with interrogation of the calf veins. (clinicaltrials.gov)
Morbidity and morta1
Venous Sinus Thrombosis1
Patients with clinically suspected1
- 2 D'Angelo A, D'Alessandro G, Tomassini L, Pittet JL, Dupuy G, Crippa L. Evaluation of a new rapid quantitative D-dimer assay in patients with clinically suspected deep vein thrombosis.Thromb Haemost. (bmj.com)
- A newer treatment involves breaking up and sucking out the clot through a small tube in the vein. (www.nhs.uk)
- People with deep-vein thrombosis can substantially cut their risk of potentially debilitating complications by starting adequate compression therapy in the first twenty-four hours of DVT therapy (known as the acute phase of treatment), suggests a study published today in the journal Blood. (news-medical.net)
- The demand for a more standardized treatment of subclavian vein thrombosis is growing. (medscape.com)
- Linked medical records using administrative healthcare data sets may provide information (eg, readmission rate or level of outpatient services) on the results of treatment of large numbers of patients with subclavian vein thrombosis or significant risk factors (eg, central venous cannulation). (medscape.com)
- Thus, although she was aware of the risk of thrombosis, which initiated her visit to the emergency department, she wanted to stay on estrogen treatment. (cmaj.ca)
- What is the treatment for deep vein thrombosis? (hopkinsmedicine.org)
- A gene associated with both protection against bacterial infection and excessive blood clotting could offer new insights into treatment strategies for deep-vein thrombosis -- the formation of a harmful clot in a deep vein. (redorbit.com)
- Awareness of IJV thrombosis in isolated cervical lymphadenopathy needs high diagnostic suspicion and prompt treatment to avoid fatal complication. (hindawi.com)
- When you have deep vein thrombosis (DVT), the main goal of treatment is to prevent the blood clot from growing or moving to the lungs. (adventisthealthcare.com)
- Pycnogenol may alleviate adverse effects in oncologic treatment, e.g. deep vein thrombosis. (greenmedinfo.com)
- Tampa General Hospital provides treatment for deep vein thrombosis and many other vascular conditions. (tgh.org)
Clot in a deep vein4
- There are many factors that can cause a blood clot in a deep vein. (medicinenet.com)
- Deep vein thrombosis -- a blood clot in a deep vein, often in your leg -- can look like many other health problems. (webmd.com)
- Deep vein thrombosis (DVT), is the formation of a blood clot in a deep vein, most commonly the legs. (wikipedia.org)
- Some things can raise your risk of getting a blood clot in a deep vein. (cdc.gov)
- damage to veins, like that from major trauma such as a broken pelvis. (sheknows.com)
- Most commonly, deep vein thrombosis occurs in a vein of the leg, but it can also occur in other locations such as the pelvis. (medicinenet.com)
- formation of one or more thrombi in the deep veins, usually of the lower extremity or in the pelvis. (drugs.com)
- DVT can also affect the deep veins of the arms, pelvis or abdomen. (targetwoman.com)
- The compression of a large tummy, blood and hormonal changes, increased pressure in the veins in the pelvis and legs make pregnant women vulnerable to DVT. (targetwoman.com)
Chance of getting a bl1
Blood clot breaks1
- In 1884, von Schrötter postulated that this syndrome resulted from occlusive thrombosis of the subclavian and axillary veins. (medscape.com)
- Chronic axillary-subclavian vein thrombosis (ASVT) rarely responds to thrombolytics and generally is better treated either conservatively with warfarin or, if symptoms are severe, with surgical bypass. (medscape.com)
- We report a case of a 38-year-old triathlete with symptoms of an axillary vein thrombosis 48h after a long triathlon competition. (tripdatabase.com)
- [ 1 ] He coined the name gouty phlebitis to describe the spontaneous thrombosis of the veins draining the upper extremity. (medscape.com)
- For example, in cases of venous trauma the predominant factor in development of thrombosis is endothelial injury, whereas in spontaneous thrombosis hypercoagulability and venous stasis are the most important thrombogenic factors. (scielo.br)
- Deep vein thrombosis (DVT) is a condition in which a blood clot develops in the deep veins, most commonly in the lower extremities. (cdc.gov)
- Gel-like clumps of congealed blood can form in one of the veins, most commonly deep in the leg. (medicalnewstoday.com)
- Deep Vein Thrombosis or DVT is commonly known as a blood clot. (brainline.org)
- During long-term venous catheterization of the subclavian vein and internal jugular vein in cancer patients, the risks of complications appear to be similar. (medscape.com)
- However, the risk of mechanical complications via the internal jugular vein appear to be higher. (medscape.com)
- Internal jugular vein (IJV) thrombosis is a rare complication in tuberculous cervical lymphadenopathy. (hindawi.com)
- Cancer can grow in and around veins, causing venous stasis, and can also stimulate increased levels of tissue factor. (wikipedia.org)
- People being treated for cancer and cancer survivors have a higher risk of getting a blood clot in a vein, which can cause serious health problems. (cdc.gov)
- Things that make blood more likely to clot, such as genetic disorders and cancer, are other big triggers for deep-vein thrombosis. (harvard.edu)
- Elevated levels of soluble fibrin or D-dimer indicate high risk of thrombosis.J Thromb Haemost.2006;4:1253-8. (bmj.com)
- The subclavian vein should be avoided for both long- and short-term hemodialysis because the risk of thrombosis is very high. (medscape.com)
- Jobst brochure entitled, Venous Thrombosis in the High-Risk Patient, Form 945 (1987). (google.com)
- Am I at risk of deep vein thrombosis? (netdoctor.co.uk)
- This is minor surgery so you shouldn't be at any extra significant risk of deep vein thrombosis (DVT) with the timescale involved. (netdoctor.co.uk)
- What are the risk factors for deep vein thrombosis? (hopkinsmedicine.org)
- If you are experiencing DVT, the blood clot that is in the vein could break off and travel through your bloodstream, which can put your health at risk. (bmc.org)
- The value of family history as a risk indicator for venous thrombosis. (epnet.com)
- Prolonged sitting on transcontinental airline flights, prolonged car rides subject travelers to an increased risk of clot formation in the legs called "deep vein thrombosis" or DVT . (northshore.org)
- CNN reports that neither dehydration, drinking alcoholic beverages, nor sitting in economy class will increase the risk of DVT (Deep Vein Thrombosis). (smartertravel.com)
- A study conducted by the UK Department for Transport on the health disturbances associated with long hours of travel has now revealed that the risk of developing deep vein thrombosis (DVT) could be greater among long distance travelers. (medindia.net)
- A new study released in today's Annals of Internal Medicine suggests a heightened risk of deep vein thrombosis (DVT) during long-distance travel. (consumerreports.org)
- Surgery and any other injury to the veins are major risk factors for developing DVT, because they slow your blood flow. (everydayhealth.com)
- Fliers beware: Are you at risk for deep vein thrombosis? (gadling.com)
- The company has created this detailed visual based on numerous studies explaining how travelers who are taking long flights are at risk for deep vein thrombosis (DVT) and how they can improve circulation in their legs and feet. (gadling.com)
- We concluded that OC users, and patients with factor V Leiden, the prothrombin G20 120A mutation, and hyperhomocysteinemia are at a significantly increased risk of cerebral vein thrombosis. (greenmedinfo.com)
- Levothyroxine administration is associated with altered fibrinolysis and coagulation, indicating it may increase the risk of venous thrombosis. (greenmedinfo.com)
- The major risk factor for development of DVT is presence of a central venous catheter in which up to 30% of patients may develop venous thrombosis. (clinicaltrials.gov)
- When a clot forms in superficial vein, meaning a vein near the surface of the skin, it is called phlebitis and does not have the risk of embolization. (everydayhealth.com)
- A particular health risk largely associated with frequent air travel is developing DVT or deep vein thrombosis. (targetwoman.com)
- Pregnancy - The increased pressure on veins caused by pregnancy heightens the risk of DVT for up to six weeks after delivery. (tgh.org)
- This procedure is designed to rapidly break up the clot, restore blood flow within the vein, and potentially preserve valve function to minimize the risk of post-thrombotic syndrome (a common condition in which the clot remains in the leg because the patient was treated with anticoagulants alone). (gwhospital.com)
- To do this, they insert a small instrument through a catheter into a vein. (healthline.com)
- During the procedure, a surgeon feeds a catheter into the blocked vein. (healthline.com)
- The catheter has a deflated balloon at its tip, which the surgeon inflates once it's in the vein. (healthline.com)
- Catheter placed in a central vein - this is a tube that is placed into a main vein of the body so that fluids and medications can be administered. (labtestsonline.org)
- However, for short-term catheterization, subclavian vein catheterization is recommended because of the decreased risks of thrombotic complications and catheter colonization by skin flora. (medscape.com)
- Differentiating catheter-associated subclavian vein thrombosis and Paget-von Schrötter syndrome is important because they appear to have different natural histories. (medscape.com)
- Having a catheter in a central vein. (cdc.gov)
- Play media Common signs and symptoms of DVT include pain or tenderness, swelling, warmth, redness or discoloration, and distention of surface veins, although about half of those with the condition have no symptoms. (wikipedia.org)
- The following may be signs and symptoms of a deep vein thrombosis. (medicalnewstoday.com)
- If so, you may be experiencing signs of deep vein thrombosis (DVT). (bmc.org)
- Only about half of the people with deep vein thrombosis show signs or symptoms of the condition. (consumerinjurylawyers.com)
- The signs or symptoms include swelling, tenderness, and redness of the leg affected by a deep vein clot. (consumerinjurylawyers.com)
- During the physical exam, the blood pressure of your heart and lungs will be checked, and your legs assessed for signs of deep venous thrombosis (e.g., swelling of leg or along a vein). (ucsd.edu)